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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ITGA9-CTDSPL (FusionGDB2 ID:40464)

Fusion Gene Summary for ITGA9-CTDSPL

check button Fusion gene summary
Fusion gene informationFusion gene name: ITGA9-CTDSPL
Fusion gene ID: 40464
HgeneTgene
Gene symbol

ITGA9

CTDSPL

Gene ID

3680

10217

Gene nameintegrin subunit alpha 9CTD small phosphatase like
SynonymsALPHA-RLC|ITGA4L|RLCC3orf8|HYA22|PSR1|RBSP3|SCP3
Cytomap

3p22.2

3p22.2

Type of geneprotein-codingprotein-coding
Descriptionintegrin alpha-9integrin alpha-RLCCTD small phosphatase-like proteinCTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-likeCTDSP-likeNIF-like proteinNLI-interacting factor 1RB protein serine phosphatase from chromosome 3carboxy-terminal domain RNA poly
Modification date2020031320200313
UniProtAcc.

Q05D32

Ensembl transtripts involved in fusion geneENST00000264741, ENST00000422441, 
ENST00000310189, ENST00000273179, 
ENST00000443503, 
Fusion gene scores* DoF score12 X 8 X 10=96010 X 10 X 5=500
# samples 1313
** MAII scorelog2(13/960*10)=-2.88452278258006
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/500*10)=-1.94341647163363
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ITGA9 [Title/Abstract] AND CTDSPL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointCTDSPL(37903769)-ITGA9(37774203), # samples:2
ITGA9(37523098)-CTDSPL(37988548), # samples:1
ITGA9(37670827)-CTDSPL(37988548), # samples:1
Anticipated loss of major functional domain due to fusion event.CTDSPL-ITGA9 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
CTDSPL-ITGA9 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ITGA9-CTDSPL seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
ITGA9-CTDSPL seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ITGA9 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CTDSPL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AC-A2BK-01AITGA9chr3

37523098

+CTDSPLchr3

37988548

+
ChimerDB4LUSCTCGA-NC-A5HI-01AITGA9chr3

37670827

+CTDSPLchr3

37988548

+


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Fusion Gene ORF analysis for ITGA9-CTDSPL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000264741ENST00000310189ITGA9chr3

37523098

+CTDSPLchr3

37988548

+
5CDS-intronENST00000264741ENST00000310189ITGA9chr3

37670827

+CTDSPLchr3

37988548

+
5CDS-intronENST00000422441ENST00000310189ITGA9chr3

37523098

+CTDSPLchr3

37988548

+
5CDS-intronENST00000422441ENST00000310189ITGA9chr3

37670827

+CTDSPLchr3

37988548

+
Frame-shiftENST00000264741ENST00000273179ITGA9chr3

37670827

+CTDSPLchr3

37988548

+
Frame-shiftENST00000264741ENST00000443503ITGA9chr3

37670827

+CTDSPLchr3

37988548

+
Frame-shiftENST00000422441ENST00000273179ITGA9chr3

37670827

+CTDSPLchr3

37988548

+
Frame-shiftENST00000422441ENST00000443503ITGA9chr3

37670827

+CTDSPLchr3

37988548

+
In-frameENST00000264741ENST00000273179ITGA9chr3

37523098

+CTDSPLchr3

37988548

+
In-frameENST00000264741ENST00000443503ITGA9chr3

37523098

+CTDSPLchr3

37988548

+
In-frameENST00000422441ENST00000273179ITGA9chr3

37523098

+CTDSPLchr3

37988548

+
In-frameENST00000422441ENST00000443503ITGA9chr3

37523098

+CTDSPLchr3

37988548

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000264741ITGA9chr337523098+ENST00000443503CTDSPLchr337988548+51218002501518422
ENST00000264741ITGA9chr337523098+ENST00000273179CTDSPLchr337988548+51548002501551433
ENST00000422441ITGA9chr337523098+ENST00000443503CTDSPLchr337988548+51258042541522422
ENST00000422441ITGA9chr337523098+ENST00000273179CTDSPLchr337988548+51588042541555433

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000264741ENST00000443503ITGA9chr337523098+CTDSPLchr337988548+0.0004897410.9995103
ENST00000264741ENST00000273179ITGA9chr337523098+CTDSPLchr337988548+0.0006001150.9993999
ENST00000422441ENST00000443503ITGA9chr337523098+CTDSPLchr337988548+0.0004895230.9995105
ENST00000422441ENST00000273179ITGA9chr337523098+CTDSPLchr337988548+0.0006001820.9993998

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Fusion Genomic Features for ITGA9-CTDSPL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ITGA9chr337523098+CTDSPLchr337988547+0.0021178830.99788207
ITGA9chr337670827+CTDSPLchr337988547+0.0008268310.9991731
ITGA9chr337523098+CTDSPLchr337988547+0.0021178830.99788207
ITGA9chr337670827+CTDSPLchr337988547+0.0008268310.9991731

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ITGA9-CTDSPL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:37903769/chr3:37774203)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CTDSPL

Q05D32

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Probable phosphatase. {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428111_1741811036.0RepeatFG-GAP 2
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+42835_961811036.0RepeatFG-GAP 1
TgeneCTDSPLchr3:37523098chr3:37988548ENST0000027317908102_26026277.0DomainFCP1 homology
TgeneCTDSPLchr3:37523098chr3:37988548ENST0000044350307102_26026266.0DomainFCP1 homology

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428312_3201811036.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428373_3811811036.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428435_4431811036.0Calcium bindingOntology_term=ECO:0000255
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+4281005_10091811036.0MotifNote=GFFKR motif
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428182_2321811036.0RepeatFG-GAP 3
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428233_2891811036.0RepeatFG-GAP 4
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428290_3491811036.0RepeatFG-GAP 5
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428351_4081811036.0RepeatFG-GAP 6
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428411_4741811036.0RepeatFG-GAP 7
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+4281003_10351811036.0Topological domainCytoplasmic
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+42830_9811811036.0Topological domainExtracellular
HgeneITGA9chr3:37523098chr3:37988548ENST00000264741+428982_10021811036.0TransmembraneHelical


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Fusion Gene Sequence for ITGA9-CTDSPL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>40464_40464_1_ITGA9-CTDSPL_ITGA9_chr3_37523098_ENST00000264741_CTDSPL_chr3_37988548_ENST00000273179_length(transcript)=5154nt_BP=800nt
CCGGCCCGGGACCCGCTCGCGCAGACTTCTCGGGCGGACTGAGGACGCCGCCGCTCGGGGCCGCCCCTGTGCTCGCCTTCAGCGCCCGCT
CAGCCCGCCGTCCGCGCCCCGGTGGCGGGCCCGACGCCCGCATTCCGCCCGTGTCCAGGCGCAGAGCTCCCGCCCCGGGGAGCTTCCTGG
CCGTCGGCGGGCCCCGCGGCCCGCGCGCTCGGCGCCCTGCTCGCCGGGCAGAGGGGAAGGCGGCGGCCGGCTGGGGATGGGCGGCCCGGC
TGCGCCGAGGGGCGCCGGGAGGCTCCGCGCGCTGCTGCTGGCGCTGGTGGTCGCGGGGATCCCCGCGGGCGCCTACAACCTCGACCCGCA
GCGCCCCGTGCACTTCCAGGGCCCCGCTGACTCGTTCTTCGGCTACGCAGTTCTGGAGCATTTCCACGACAACACGCGCTGGGTCCTTGT
GGGCGCACCAAAGGCAGATTCCAAATACAGCCCTTCAGTGAAGTCTCCTGGGGCTGTGTTTAAGTGCCGTGTTCACACCAACCCTGACCG
GAGATGCACCGAACTGGACATGGCTCGAGGGAAGAATCGGGGCACGTCCTGCGGAAAGACCTGCCGGGAAGACCGCGATGATGAGTGGAT
GGGGGTGAGCCTGGCCCGACAGCCCAAGGCTGATGGCCGTGTGTTGGCCTGTGCTCATCGCTGGAAGAACATCTACTATGAAGCCGACCA
CATCCTACCCCATGGCTTCTGCTACATCATCCCCTCCAACCTCCAGGCCAAAGGCAGGACGCTGATCCCTTGCTATGAAGCCTCCCAGTG
CAACGTCAGCTTAAAGAAGCAGAGGAGCCGCAGCATCCTTAGCTCCTTCTTCTGCTGCTTCCGTGATTACAATGTGGAGGCCCCTCCACC
CAGCAGCCCCAGTGTGCTTCCGCCACTGGTGGAGGAGAATGGTGGGCTTCAGAAGGGTGACCAGAGGCAGGTCATTCCCATACCAAGTCC
ACCAGCTAAGTACCTTCTTCCAGAGGTGACGGTGCTTGACTATGGAAAGAAATGTGTGGTCATTGATTTAGATGAAACATTGGTGCACAG
TTCGTTTAAGCCTATTAGTAATGCTGATTTTATTGTTCCGGTTGAAATCGATGGAACTATACATCAGGTGTATGTGCTGAAGCGGCCACA
TGTGGACGAGTTCCTCCAGAGGATGGGGCAGCTTTTTGAATGTGTGCTCTTTACTGCCAGCTTGGCCAAGTATGCAGACCCTGTGGCTGA
CCTCCTAGACCGCTGGGGTGTGTTCCGGGCCCGGCTCTTCAGAGAATCATGTGTTTTTCATCGTGGGAACTACGTGAAGGACCTGAGTCG
CCTTGGGCGGGAGCTGAGCAAAGTGATCATTGTTGACAATTCCCCTGCCTCATACATCTTCCATCCTGAGAATGCAGTGCCTGTGCAGTC
CTGGTTCGATGACATGACGGACACGGAGCTGCTGGACCTCATCCCCTTCTTTGAGGGCCTGAGCCGGGAGGACGACGTGTACAGCATGCT
GCACAGACTCTGCAATAGGTAGCCCTGGCCTCTGCCTGCCTCCCGCCTGTGCACTCTGGAACCTCTGGCCTCAGGGGACCTGCCTGTCCT
CAGCTCCCTGGGAGCTGAAAGTGAGGATACTCCGTGCTCCAGGCCACAGGGTGAATGTGGCCATGCCTACCTGTTTTGTTTTTTTAAGAA
CAGAAACAACTATTTTAAAAGAACTCTTTTAAGAAATTTCATAAAGGGACATGCATTTTACTGGGTTTGCTTTTCTTAAAACATACCAAA
AAAGAAAAAAATAGAAAAAAAAAAAAAAAAAGCTTGATCTCTATCAGACTTCCTTTCAACTGTCCTCCCCTCCAAGCAGACCACCTGTCC
CCTTCTATCCCAGCTCAGAGCAGCTGACCCAACTCAGAATCTCTTTCCTACAGGATGAAGTGCCTTTTGAATGTTATTTTAAGCCGAGAG
TTAATTTTTCTACACAACATATTTCCAGACATCTTTTAGTCTTTTATTGTCTTAGATACTATAAGAAGATGAACATGACAATTTTCTAGA
ACCTGGTAGCGTGTGTGTGTGTGGCGGGGGGTGCTGAGGGAGGGGAGTGAGTCACAGGAGCCTGTCCCCCAACAGGTGTGACTGCTCTGA
CAACCTGTGGCATGCTGCAGGGTCAGGCTCCTGATAGGAGGATTTCATGACTATGTCATTGTCTCCACTCATTTTTGACCCAGTTTGGAA
TGTATCTGCAATTGTGTGGCTCAACACTTTAGGAAACAATAGATTATTTTATATTATTATTTCTGATGGTGACAAGTTTGTCTTGAGGTC
ACATTTTCTCCTTGAAAAGTGACATCCTGTCACTTCTGCTCTCACACTACTGCCATACATTTGTGTTTTTTGTTGTTATTGTTTGGGTAG
AGCAGTTACAAGAAACCCTAAAACCCTTGGATATAAAAGAAATCTGTTTATTGATTTTTAAATCTTTCCTTTCCAAAAGCTGGATACACA
TGGAGCTGTTTGGGAATTTTCCTTGCTGCTACCGCGCTGCCACCAAATGGAATTGACCAGCGGCTGTTACACTGTTCTTTGCCACTGTGC
CTATGCTCAGAATATGCTCACTGCTAAGCTACAAACTCGGACAGGGTCAGAAACAGAGGTGTCCCATCCCATTGCAGCCTCCACCACCTG
TAACCCCTTCCTGGCATTGGCCACTGAAGGGTACAAAGGCAAAAGGACCACAGCACCACTTAGGTGTAGCATGGATTTTAAACTGCAGTC
AGTATCAGATCCTGTTTGATAAATAAGCTGACTGTTCTCTCTTGAGAACCTGTGGCCTCAACCAGCCACCAAGCTGATGTGGCCCAAGTC
CATCTCTTGGTCTTCTCCTTTGAAGCACAGCCTATTTCTGAGCCAAGGGTTGGGGAAGCCTGTCTAGATGTGGGACTCATTGCCCCAAAC
CAGGGAGAGGAAGAGCTCCCACAGGGAGAGCCCAGGCTCTCTTTGCAGCCTTTCCCAGTTTGGTGTTTAAGCAGTGCCATGTTCCTTGTT
TGACAACAAGACAGTCTGTAAAGTATTGCTCTTAAAAACAATTAAAAAGAACCCTTTCATATTGGCACCATTGCCTTAGTCCTCTGTGGG
TTGGTCTTCAGCCAGCATTCTGGTGGGAGTGACTGGCATTAACAAGACTGGAAATCGGGGGTCAAAGTAAAATATCTTTGTTTTGCTTTC
ATTCACAAAGTAATGAAGCCAGCTGCCAATTACATCCTCCCAACAGCACTTTGGTCTGTGGACTGCTGTGTGAATATTCAGAAGGGAAGT
AAGTATTCAGGGGGTAAACAGGTCTCCCAGCATTCTGAGTGTTCCAAACCAGTAATCCACATGCCAATTCAAATAGAACAGCCCCTTGCT
AGATATTACCACAGATAATGACAGTTACATGGTAGAACTGCCCATGCCACAAATATTTATTTGGAAAAGTAGTCATTAAATGAACCCACT
GCCTTAAATGTCTTGAATGTTGCAGTCAAGTGTCTGTCATGTGTTGATATCCACACAGAATTAGGCCCTAATGAGAGCCTTAGACCCTCA
ACCATGCCCCCTTCGTTGGCATCACAGGGCCTTATTTGGAAGAGCGGGCAAAGAGGATGGAAATCATAAAATATTTCATGGGAATCGAAC
CTAGGGATAGTGCTCCACTTCTGACGATGGAGTGAAGACACTTGGCAGACTTGAGCCAGACACTTCACCTAGTAGTTCCTGAAACTGTGA
GCACCACTGCACTAAGCCAGTGCGGAGCTGTTAGGGACGGGCCCAGCTCCTGCACCACGGACACAGAATGTCTGGAGAGGGCCAGCAGGC
CCTCTGAGGGTTCTGGAATCTGTGCACCTTATTTGACCACACTCCAAAATTCTGTTTTTATTTTAACCCTTGAATCTGCTTTATGTACAT
AATCAAAATATCTATATCTATATCTATATCTATATCTATATATTTTTAATCATCTACATGTAAATGAAGCAATAGAATTCTAACATAAGG
CCAAGAAATGAGACGAATGTTTGGGGTTTATGTTTTTTAAGGTAAATACGGGTATTGTTTTTAATTATTACCATGTATTAAATTGTGGGC
TTTGAAACCTAATGAAACCTGTTAGCCACTTCTCTGTGCCATATACTTCCCATGTTACCAAAATACCCCCAACTCTTTAGCCAAAAGAGA
ACCCTGACCTCCTGAGTTTCCATGCTCCTTTCTGTACCAGGTTTAAATGTAGTCTTCTGGAGAAGTATTTTTGACATTGAGCTCTGGGAC
AGGACACCTTGGGTTTGTGGACTGCAGCCCACTATGATGTTATTACTTCTCTGGCCAGGCCTCCAGTGGAAGTGCACAGGCACTCCCAAT
GTTGTTAATGCTCTGTCTTCCATTTGTTCTGGAATCCTACGTGTTGGTCTGTGGTTCCATGCATTAGCTGTTTGTAAATAATGCATTTGC
ATACTGAAAAAGGAATGCCACCTGCCACAGTTGATGGTGAGGAAGCTCCTTTGACGTGGTGCAATTTTGATGAGATGTCTCTGGGGACAC
GAGGATGCCCTAATGATGCTGACTTGTCATGGTTGCAGCATTTGAACTTTTGGTGTTAAAAAAAAAAACCTGTAAGTCTGTAACCTGGCA
ACATTTTACAACCCTGTATTTTTAAAGATGGCTTTCTAATAAAAAATCCAGAACCACACAGCCCTATGGTCAAACAATCCTACGTTTGTG
CCTCTGCTTTTAAAGGTGCTGTGCTGGACAGTTGGCATGCCAGGGTTCGAGAAGAGTGAATGGCTTGACGTACTTGCAGTTAACTGTGCA
AAATTGGCTGGCTGCCTCTGTTCCTACTGTACTGTAACTTTGATCATGTCTGTTCCTGTTCCATTCTCCCAGGAGCTTCTCTGCAGACTG
ACACACCCTCCCCCACCCCGGGTAGTGGAGATGCTGGTGTCTGGGTAGTCATGGATTTCTGCTGGACATTTGAATGTGATAAACAATCCA
GCATTACTTAGGAAATGCTACATGCGGAATGTGCACGTTTCCAGGGGCGAGTATTGTCAATCAAAAGGTTTGCAATGATTTCCTTCCTGC

>40464_40464_1_ITGA9-CTDSPL_ITGA9_chr3_37523098_ENST00000264741_CTDSPL_chr3_37988548_ENST00000273179_length(amino acids)=433AA_BP=1
MGMGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCR
VHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIP
CYEASQCNVSLKKQRSRSILSSFFCCFRDYNVEAPPPSSPSVLPPLVEENGGLQKGDQRQVIPIPSPPAKYLLPEVTVLDYGKKCVVIDL
DETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGN

--------------------------------------------------------------
>40464_40464_2_ITGA9-CTDSPL_ITGA9_chr3_37523098_ENST00000264741_CTDSPL_chr3_37988548_ENST00000443503_length(transcript)=5121nt_BP=800nt
CCGGCCCGGGACCCGCTCGCGCAGACTTCTCGGGCGGACTGAGGACGCCGCCGCTCGGGGCCGCCCCTGTGCTCGCCTTCAGCGCCCGCT
CAGCCCGCCGTCCGCGCCCCGGTGGCGGGCCCGACGCCCGCATTCCGCCCGTGTCCAGGCGCAGAGCTCCCGCCCCGGGGAGCTTCCTGG
CCGTCGGCGGGCCCCGCGGCCCGCGCGCTCGGCGCCCTGCTCGCCGGGCAGAGGGGAAGGCGGCGGCCGGCTGGGGATGGGCGGCCCGGC
TGCGCCGAGGGGCGCCGGGAGGCTCCGCGCGCTGCTGCTGGCGCTGGTGGTCGCGGGGATCCCCGCGGGCGCCTACAACCTCGACCCGCA
GCGCCCCGTGCACTTCCAGGGCCCCGCTGACTCGTTCTTCGGCTACGCAGTTCTGGAGCATTTCCACGACAACACGCGCTGGGTCCTTGT
GGGCGCACCAAAGGCAGATTCCAAATACAGCCCTTCAGTGAAGTCTCCTGGGGCTGTGTTTAAGTGCCGTGTTCACACCAACCCTGACCG
GAGATGCACCGAACTGGACATGGCTCGAGGGAAGAATCGGGGCACGTCCTGCGGAAAGACCTGCCGGGAAGACCGCGATGATGAGTGGAT
GGGGGTGAGCCTGGCCCGACAGCCCAAGGCTGATGGCCGTGTGTTGGCCTGTGCTCATCGCTGGAAGAACATCTACTATGAAGCCGACCA
CATCCTACCCCATGGCTTCTGCTACATCATCCCCTCCAACCTCCAGGCCAAAGGCAGGACGCTGATCCCTTGCTATGAAGCCTCCCAGTG
CAACGTCAGCTTAAAGAAGCAGAGGAGCCGCAGCATCCTTAGCTCCTTCTTCTGCTGCTTCCGTGATTACAATGTGGAGGCCCCTCCACC
CAGCAGCCCCAGTGTGCTTCCGCCACTGGTGGAGGAGAATGGTGGGCTTCAGAAGCCACCAGCTAAGTACCTTCTTCCAGAGGTGACGGT
GCTTGACTATGGAAAGAAATGTGTGGTCATTGATTTAGATGAAACATTGGTGCACAGTTCGTTTAAGCCTATTAGTAATGCTGATTTTAT
TGTTCCGGTTGAAATCGATGGAACTATACATCAGGTGTATGTGCTGAAGCGGCCACATGTGGACGAGTTCCTCCAGAGGATGGGGCAGCT
TTTTGAATGTGTGCTCTTTACTGCCAGCTTGGCCAAGTATGCAGACCCTGTGGCTGACCTCCTAGACCGCTGGGGTGTGTTCCGGGCCCG
GCTCTTCAGAGAATCATGTGTTTTTCATCGTGGGAACTACGTGAAGGACCTGAGTCGCCTTGGGCGGGAGCTGAGCAAAGTGATCATTGT
TGACAATTCCCCTGCCTCATACATCTTCCATCCTGAGAATGCAGTGCCTGTGCAGTCCTGGTTCGATGACATGACGGACACGGAGCTGCT
GGACCTCATCCCCTTCTTTGAGGGCCTGAGCCGGGAGGACGACGTGTACAGCATGCTGCACAGACTCTGCAATAGGTAGCCCTGGCCTCT
GCCTGCCTCCCGCCTGTGCACTCTGGAACCTCTGGCCTCAGGGGACCTGCCTGTCCTCAGCTCCCTGGGAGCTGAAAGTGAGGATACTCC
GTGCTCCAGGCCACAGGGTGAATGTGGCCATGCCTACCTGTTTTGTTTTTTTAAGAACAGAAACAACTATTTTAAAAGAACTCTTTTAAG
AAATTTCATAAAGGGACATGCATTTTACTGGGTTTGCTTTTCTTAAAACATACCAAAAAAGAAAAAAATAGAAAAAAAAAAAAAAAAAGC
TTGATCTCTATCAGACTTCCTTTCAACTGTCCTCCCCTCCAAGCAGACCACCTGTCCCCTTCTATCCCAGCTCAGAGCAGCTGACCCAAC
TCAGAATCTCTTTCCTACAGGATGAAGTGCCTTTTGAATGTTATTTTAAGCCGAGAGTTAATTTTTCTACACAACATATTTCCAGACATC
TTTTAGTCTTTTATTGTCTTAGATACTATAAGAAGATGAACATGACAATTTTCTAGAACCTGGTAGCGTGTGTGTGTGTGGCGGGGGGTG
CTGAGGGAGGGGAGTGAGTCACAGGAGCCTGTCCCCCAACAGGTGTGACTGCTCTGACAACCTGTGGCATGCTGCAGGGTCAGGCTCCTG
ATAGGAGGATTTCATGACTATGTCATTGTCTCCACTCATTTTTGACCCAGTTTGGAATGTATCTGCAATTGTGTGGCTCAACACTTTAGG
AAACAATAGATTATTTTATATTATTATTTCTGATGGTGACAAGTTTGTCTTGAGGTCACATTTTCTCCTTGAAAAGTGACATCCTGTCAC
TTCTGCTCTCACACTACTGCCATACATTTGTGTTTTTTGTTGTTATTGTTTGGGTAGAGCAGTTACAAGAAACCCTAAAACCCTTGGATA
TAAAAGAAATCTGTTTATTGATTTTTAAATCTTTCCTTTCCAAAAGCTGGATACACATGGAGCTGTTTGGGAATTTTCCTTGCTGCTACC
GCGCTGCCACCAAATGGAATTGACCAGCGGCTGTTACACTGTTCTTTGCCACTGTGCCTATGCTCAGAATATGCTCACTGCTAAGCTACA
AACTCGGACAGGGTCAGAAACAGAGGTGTCCCATCCCATTGCAGCCTCCACCACCTGTAACCCCTTCCTGGCATTGGCCACTGAAGGGTA
CAAAGGCAAAAGGACCACAGCACCACTTAGGTGTAGCATGGATTTTAAACTGCAGTCAGTATCAGATCCTGTTTGATAAATAAGCTGACT
GTTCTCTCTTGAGAACCTGTGGCCTCAACCAGCCACCAAGCTGATGTGGCCCAAGTCCATCTCTTGGTCTTCTCCTTTGAAGCACAGCCT
ATTTCTGAGCCAAGGGTTGGGGAAGCCTGTCTAGATGTGGGACTCATTGCCCCAAACCAGGGAGAGGAAGAGCTCCCACAGGGAGAGCCC
AGGCTCTCTTTGCAGCCTTTCCCAGTTTGGTGTTTAAGCAGTGCCATGTTCCTTGTTTGACAACAAGACAGTCTGTAAAGTATTGCTCTT
AAAAACAATTAAAAAGAACCCTTTCATATTGGCACCATTGCCTTAGTCCTCTGTGGGTTGGTCTTCAGCCAGCATTCTGGTGGGAGTGAC
TGGCATTAACAAGACTGGAAATCGGGGGTCAAAGTAAAATATCTTTGTTTTGCTTTCATTCACAAAGTAATGAAGCCAGCTGCCAATTAC
ATCCTCCCAACAGCACTTTGGTCTGTGGACTGCTGTGTGAATATTCAGAAGGGAAGTAAGTATTCAGGGGGTAAACAGGTCTCCCAGCAT
TCTGAGTGTTCCAAACCAGTAATCCACATGCCAATTCAAATAGAACAGCCCCTTGCTAGATATTACCACAGATAATGACAGTTACATGGT
AGAACTGCCCATGCCACAAATATTTATTTGGAAAAGTAGTCATTAAATGAACCCACTGCCTTAAATGTCTTGAATGTTGCAGTCAAGTGT
CTGTCATGTGTTGATATCCACACAGAATTAGGCCCTAATGAGAGCCTTAGACCCTCAACCATGCCCCCTTCGTTGGCATCACAGGGCCTT
ATTTGGAAGAGCGGGCAAAGAGGATGGAAATCATAAAATATTTCATGGGAATCGAACCTAGGGATAGTGCTCCACTTCTGACGATGGAGT
GAAGACACTTGGCAGACTTGAGCCAGACACTTCACCTAGTAGTTCCTGAAACTGTGAGCACCACTGCACTAAGCCAGTGCGGAGCTGTTA
GGGACGGGCCCAGCTCCTGCACCACGGACACAGAATGTCTGGAGAGGGCCAGCAGGCCCTCTGAGGGTTCTGGAATCTGTGCACCTTATT
TGACCACACTCCAAAATTCTGTTTTTATTTTAACCCTTGAATCTGCTTTATGTACATAATCAAAATATCTATATCTATATCTATATCTAT
ATCTATATATTTTTAATCATCTACATGTAAATGAAGCAATAGAATTCTAACATAAGGCCAAGAAATGAGACGAATGTTTGGGGTTTATGT
TTTTTAAGGTAAATACGGGTATTGTTTTTAATTATTACCATGTATTAAATTGTGGGCTTTGAAACCTAATGAAACCTGTTAGCCACTTCT
CTGTGCCATATACTTCCCATGTTACCAAAATACCCCCAACTCTTTAGCCAAAAGAGAACCCTGACCTCCTGAGTTTCCATGCTCCTTTCT
GTACCAGGTTTAAATGTAGTCTTCTGGAGAAGTATTTTTGACATTGAGCTCTGGGACAGGACACCTTGGGTTTGTGGACTGCAGCCCACT
ATGATGTTATTACTTCTCTGGCCAGGCCTCCAGTGGAAGTGCACAGGCACTCCCAATGTTGTTAATGCTCTGTCTTCCATTTGTTCTGGA
ATCCTACGTGTTGGTCTGTGGTTCCATGCATTAGCTGTTTGTAAATAATGCATTTGCATACTGAAAAAGGAATGCCACCTGCCACAGTTG
ATGGTGAGGAAGCTCCTTTGACGTGGTGCAATTTTGATGAGATGTCTCTGGGGACACGAGGATGCCCTAATGATGCTGACTTGTCATGGT
TGCAGCATTTGAACTTTTGGTGTTAAAAAAAAAAACCTGTAAGTCTGTAACCTGGCAACATTTTACAACCCTGTATTTTTAAAGATGGCT
TTCTAATAAAAAATCCAGAACCACACAGCCCTATGGTCAAACAATCCTACGTTTGTGCCTCTGCTTTTAAAGGTGCTGTGCTGGACAGTT
GGCATGCCAGGGTTCGAGAAGAGTGAATGGCTTGACGTACTTGCAGTTAACTGTGCAAAATTGGCTGGCTGCCTCTGTTCCTACTGTACT
GTAACTTTGATCATGTCTGTTCCTGTTCCATTCTCCCAGGAGCTTCTCTGCAGACTGACACACCCTCCCCCACCCCGGGTAGTGGAGATG
CTGGTGTCTGGGTAGTCATGGATTTCTGCTGGACATTTGAATGTGATAAACAATCCAGCATTACTTAGGAAATGCTACATGCGGAATGTG

>40464_40464_2_ITGA9-CTDSPL_ITGA9_chr3_37523098_ENST00000264741_CTDSPL_chr3_37988548_ENST00000443503_length(amino acids)=422AA_BP=1
MGMGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCR
VHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIP
CYEASQCNVSLKKQRSRSILSSFFCCFRDYNVEAPPPSSPSVLPPLVEENGGLQKPPAKYLLPEVTVLDYGKKCVVIDLDETLVHSSFKP
ISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRE

--------------------------------------------------------------
>40464_40464_3_ITGA9-CTDSPL_ITGA9_chr3_37523098_ENST00000422441_CTDSPL_chr3_37988548_ENST00000273179_length(transcript)=5158nt_BP=804nt
CCGCCCGGCCCGGGACCCGCTCGCGCAGACTTCTCGGGCGGACTGAGGACGCCGCCGCTCGGGGCCGCCCCTGTGCTCGCCTTCAGCGCC
CGCTCAGCCCGCCGTCCGCGCCCCGGTGGCGGGCCCGACGCCCGCATTCCGCCCGTGTCCAGGCGCAGAGCTCCCGCCCCGGGGAGCTTC
CTGGCCGTCGGCGGGCCCCGCGGCCCGCGCGCTCGGCGCCCTGCTCGCCGGGCAGAGGGGAAGGCGGCGGCCGGCTGGGGATGGGCGGCC
CGGCTGCGCCGAGGGGCGCCGGGAGGCTCCGCGCGCTGCTGCTGGCGCTGGTGGTCGCGGGGATCCCCGCGGGCGCCTACAACCTCGACC
CGCAGCGCCCCGTGCACTTCCAGGGCCCCGCTGACTCGTTCTTCGGCTACGCAGTTCTGGAGCATTTCCACGACAACACGCGCTGGGTCC
TTGTGGGCGCACCAAAGGCAGATTCCAAATACAGCCCTTCAGTGAAGTCTCCTGGGGCTGTGTTTAAGTGCCGTGTTCACACCAACCCTG
ACCGGAGATGCACCGAACTGGACATGGCTCGAGGGAAGAATCGGGGCACGTCCTGCGGAAAGACCTGCCGGGAAGACCGCGATGATGAGT
GGATGGGGGTGAGCCTGGCCCGACAGCCCAAGGCTGATGGCCGTGTGTTGGCCTGTGCTCATCGCTGGAAGAACATCTACTATGAAGCCG
ACCACATCCTACCCCATGGCTTCTGCTACATCATCCCCTCCAACCTCCAGGCCAAAGGCAGGACGCTGATCCCTTGCTATGAAGCCTCCC
AGTGCAACGTCAGCTTAAAGAAGCAGAGGAGCCGCAGCATCCTTAGCTCCTTCTTCTGCTGCTTCCGTGATTACAATGTGGAGGCCCCTC
CACCCAGCAGCCCCAGTGTGCTTCCGCCACTGGTGGAGGAGAATGGTGGGCTTCAGAAGGGTGACCAGAGGCAGGTCATTCCCATACCAA
GTCCACCAGCTAAGTACCTTCTTCCAGAGGTGACGGTGCTTGACTATGGAAAGAAATGTGTGGTCATTGATTTAGATGAAACATTGGTGC
ACAGTTCGTTTAAGCCTATTAGTAATGCTGATTTTATTGTTCCGGTTGAAATCGATGGAACTATACATCAGGTGTATGTGCTGAAGCGGC
CACATGTGGACGAGTTCCTCCAGAGGATGGGGCAGCTTTTTGAATGTGTGCTCTTTACTGCCAGCTTGGCCAAGTATGCAGACCCTGTGG
CTGACCTCCTAGACCGCTGGGGTGTGTTCCGGGCCCGGCTCTTCAGAGAATCATGTGTTTTTCATCGTGGGAACTACGTGAAGGACCTGA
GTCGCCTTGGGCGGGAGCTGAGCAAAGTGATCATTGTTGACAATTCCCCTGCCTCATACATCTTCCATCCTGAGAATGCAGTGCCTGTGC
AGTCCTGGTTCGATGACATGACGGACACGGAGCTGCTGGACCTCATCCCCTTCTTTGAGGGCCTGAGCCGGGAGGACGACGTGTACAGCA
TGCTGCACAGACTCTGCAATAGGTAGCCCTGGCCTCTGCCTGCCTCCCGCCTGTGCACTCTGGAACCTCTGGCCTCAGGGGACCTGCCTG
TCCTCAGCTCCCTGGGAGCTGAAAGTGAGGATACTCCGTGCTCCAGGCCACAGGGTGAATGTGGCCATGCCTACCTGTTTTGTTTTTTTA
AGAACAGAAACAACTATTTTAAAAGAACTCTTTTAAGAAATTTCATAAAGGGACATGCATTTTACTGGGTTTGCTTTTCTTAAAACATAC
CAAAAAAGAAAAAAATAGAAAAAAAAAAAAAAAAAGCTTGATCTCTATCAGACTTCCTTTCAACTGTCCTCCCCTCCAAGCAGACCACCT
GTCCCCTTCTATCCCAGCTCAGAGCAGCTGACCCAACTCAGAATCTCTTTCCTACAGGATGAAGTGCCTTTTGAATGTTATTTTAAGCCG
AGAGTTAATTTTTCTACACAACATATTTCCAGACATCTTTTAGTCTTTTATTGTCTTAGATACTATAAGAAGATGAACATGACAATTTTC
TAGAACCTGGTAGCGTGTGTGTGTGTGGCGGGGGGTGCTGAGGGAGGGGAGTGAGTCACAGGAGCCTGTCCCCCAACAGGTGTGACTGCT
CTGACAACCTGTGGCATGCTGCAGGGTCAGGCTCCTGATAGGAGGATTTCATGACTATGTCATTGTCTCCACTCATTTTTGACCCAGTTT
GGAATGTATCTGCAATTGTGTGGCTCAACACTTTAGGAAACAATAGATTATTTTATATTATTATTTCTGATGGTGACAAGTTTGTCTTGA
GGTCACATTTTCTCCTTGAAAAGTGACATCCTGTCACTTCTGCTCTCACACTACTGCCATACATTTGTGTTTTTTGTTGTTATTGTTTGG
GTAGAGCAGTTACAAGAAACCCTAAAACCCTTGGATATAAAAGAAATCTGTTTATTGATTTTTAAATCTTTCCTTTCCAAAAGCTGGATA
CACATGGAGCTGTTTGGGAATTTTCCTTGCTGCTACCGCGCTGCCACCAAATGGAATTGACCAGCGGCTGTTACACTGTTCTTTGCCACT
GTGCCTATGCTCAGAATATGCTCACTGCTAAGCTACAAACTCGGACAGGGTCAGAAACAGAGGTGTCCCATCCCATTGCAGCCTCCACCA
CCTGTAACCCCTTCCTGGCATTGGCCACTGAAGGGTACAAAGGCAAAAGGACCACAGCACCACTTAGGTGTAGCATGGATTTTAAACTGC
AGTCAGTATCAGATCCTGTTTGATAAATAAGCTGACTGTTCTCTCTTGAGAACCTGTGGCCTCAACCAGCCACCAAGCTGATGTGGCCCA
AGTCCATCTCTTGGTCTTCTCCTTTGAAGCACAGCCTATTTCTGAGCCAAGGGTTGGGGAAGCCTGTCTAGATGTGGGACTCATTGCCCC
AAACCAGGGAGAGGAAGAGCTCCCACAGGGAGAGCCCAGGCTCTCTTTGCAGCCTTTCCCAGTTTGGTGTTTAAGCAGTGCCATGTTCCT
TGTTTGACAACAAGACAGTCTGTAAAGTATTGCTCTTAAAAACAATTAAAAAGAACCCTTTCATATTGGCACCATTGCCTTAGTCCTCTG
TGGGTTGGTCTTCAGCCAGCATTCTGGTGGGAGTGACTGGCATTAACAAGACTGGAAATCGGGGGTCAAAGTAAAATATCTTTGTTTTGC
TTTCATTCACAAAGTAATGAAGCCAGCTGCCAATTACATCCTCCCAACAGCACTTTGGTCTGTGGACTGCTGTGTGAATATTCAGAAGGG
AAGTAAGTATTCAGGGGGTAAACAGGTCTCCCAGCATTCTGAGTGTTCCAAACCAGTAATCCACATGCCAATTCAAATAGAACAGCCCCT
TGCTAGATATTACCACAGATAATGACAGTTACATGGTAGAACTGCCCATGCCACAAATATTTATTTGGAAAAGTAGTCATTAAATGAACC
CACTGCCTTAAATGTCTTGAATGTTGCAGTCAAGTGTCTGTCATGTGTTGATATCCACACAGAATTAGGCCCTAATGAGAGCCTTAGACC
CTCAACCATGCCCCCTTCGTTGGCATCACAGGGCCTTATTTGGAAGAGCGGGCAAAGAGGATGGAAATCATAAAATATTTCATGGGAATC
GAACCTAGGGATAGTGCTCCACTTCTGACGATGGAGTGAAGACACTTGGCAGACTTGAGCCAGACACTTCACCTAGTAGTTCCTGAAACT
GTGAGCACCACTGCACTAAGCCAGTGCGGAGCTGTTAGGGACGGGCCCAGCTCCTGCACCACGGACACAGAATGTCTGGAGAGGGCCAGC
AGGCCCTCTGAGGGTTCTGGAATCTGTGCACCTTATTTGACCACACTCCAAAATTCTGTTTTTATTTTAACCCTTGAATCTGCTTTATGT
ACATAATCAAAATATCTATATCTATATCTATATCTATATCTATATATTTTTAATCATCTACATGTAAATGAAGCAATAGAATTCTAACAT
AAGGCCAAGAAATGAGACGAATGTTTGGGGTTTATGTTTTTTAAGGTAAATACGGGTATTGTTTTTAATTATTACCATGTATTAAATTGT
GGGCTTTGAAACCTAATGAAACCTGTTAGCCACTTCTCTGTGCCATATACTTCCCATGTTACCAAAATACCCCCAACTCTTTAGCCAAAA
GAGAACCCTGACCTCCTGAGTTTCCATGCTCCTTTCTGTACCAGGTTTAAATGTAGTCTTCTGGAGAAGTATTTTTGACATTGAGCTCTG
GGACAGGACACCTTGGGTTTGTGGACTGCAGCCCACTATGATGTTATTACTTCTCTGGCCAGGCCTCCAGTGGAAGTGCACAGGCACTCC
CAATGTTGTTAATGCTCTGTCTTCCATTTGTTCTGGAATCCTACGTGTTGGTCTGTGGTTCCATGCATTAGCTGTTTGTAAATAATGCAT
TTGCATACTGAAAAAGGAATGCCACCTGCCACAGTTGATGGTGAGGAAGCTCCTTTGACGTGGTGCAATTTTGATGAGATGTCTCTGGGG
ACACGAGGATGCCCTAATGATGCTGACTTGTCATGGTTGCAGCATTTGAACTTTTGGTGTTAAAAAAAAAAACCTGTAAGTCTGTAACCT
GGCAACATTTTACAACCCTGTATTTTTAAAGATGGCTTTCTAATAAAAAATCCAGAACCACACAGCCCTATGGTCAAACAATCCTACGTT
TGTGCCTCTGCTTTTAAAGGTGCTGTGCTGGACAGTTGGCATGCCAGGGTTCGAGAAGAGTGAATGGCTTGACGTACTTGCAGTTAACTG
TGCAAAATTGGCTGGCTGCCTCTGTTCCTACTGTACTGTAACTTTGATCATGTCTGTTCCTGTTCCATTCTCCCAGGAGCTTCTCTGCAG
ACTGACACACCCTCCCCCACCCCGGGTAGTGGAGATGCTGGTGTCTGGGTAGTCATGGATTTCTGCTGGACATTTGAATGTGATAAACAA
TCCAGCATTACTTAGGAAATGCTACATGCGGAATGTGCACGTTTCCAGGGGCGAGTATTGTCAATCAAAAGGTTTGCAATGATTTCCTTC

>40464_40464_3_ITGA9-CTDSPL_ITGA9_chr3_37523098_ENST00000422441_CTDSPL_chr3_37988548_ENST00000273179_length(amino acids)=433AA_BP=1
MGMGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCR
VHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIP
CYEASQCNVSLKKQRSRSILSSFFCCFRDYNVEAPPPSSPSVLPPLVEENGGLQKGDQRQVIPIPSPPAKYLLPEVTVLDYGKKCVVIDL
DETLVHSSFKPISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGN

--------------------------------------------------------------
>40464_40464_4_ITGA9-CTDSPL_ITGA9_chr3_37523098_ENST00000422441_CTDSPL_chr3_37988548_ENST00000443503_length(transcript)=5125nt_BP=804nt
CCGCCCGGCCCGGGACCCGCTCGCGCAGACTTCTCGGGCGGACTGAGGACGCCGCCGCTCGGGGCCGCCCCTGTGCTCGCCTTCAGCGCC
CGCTCAGCCCGCCGTCCGCGCCCCGGTGGCGGGCCCGACGCCCGCATTCCGCCCGTGTCCAGGCGCAGAGCTCCCGCCCCGGGGAGCTTC
CTGGCCGTCGGCGGGCCCCGCGGCCCGCGCGCTCGGCGCCCTGCTCGCCGGGCAGAGGGGAAGGCGGCGGCCGGCTGGGGATGGGCGGCC
CGGCTGCGCCGAGGGGCGCCGGGAGGCTCCGCGCGCTGCTGCTGGCGCTGGTGGTCGCGGGGATCCCCGCGGGCGCCTACAACCTCGACC
CGCAGCGCCCCGTGCACTTCCAGGGCCCCGCTGACTCGTTCTTCGGCTACGCAGTTCTGGAGCATTTCCACGACAACACGCGCTGGGTCC
TTGTGGGCGCACCAAAGGCAGATTCCAAATACAGCCCTTCAGTGAAGTCTCCTGGGGCTGTGTTTAAGTGCCGTGTTCACACCAACCCTG
ACCGGAGATGCACCGAACTGGACATGGCTCGAGGGAAGAATCGGGGCACGTCCTGCGGAAAGACCTGCCGGGAAGACCGCGATGATGAGT
GGATGGGGGTGAGCCTGGCCCGACAGCCCAAGGCTGATGGCCGTGTGTTGGCCTGTGCTCATCGCTGGAAGAACATCTACTATGAAGCCG
ACCACATCCTACCCCATGGCTTCTGCTACATCATCCCCTCCAACCTCCAGGCCAAAGGCAGGACGCTGATCCCTTGCTATGAAGCCTCCC
AGTGCAACGTCAGCTTAAAGAAGCAGAGGAGCCGCAGCATCCTTAGCTCCTTCTTCTGCTGCTTCCGTGATTACAATGTGGAGGCCCCTC
CACCCAGCAGCCCCAGTGTGCTTCCGCCACTGGTGGAGGAGAATGGTGGGCTTCAGAAGCCACCAGCTAAGTACCTTCTTCCAGAGGTGA
CGGTGCTTGACTATGGAAAGAAATGTGTGGTCATTGATTTAGATGAAACATTGGTGCACAGTTCGTTTAAGCCTATTAGTAATGCTGATT
TTATTGTTCCGGTTGAAATCGATGGAACTATACATCAGGTGTATGTGCTGAAGCGGCCACATGTGGACGAGTTCCTCCAGAGGATGGGGC
AGCTTTTTGAATGTGTGCTCTTTACTGCCAGCTTGGCCAAGTATGCAGACCCTGTGGCTGACCTCCTAGACCGCTGGGGTGTGTTCCGGG
CCCGGCTCTTCAGAGAATCATGTGTTTTTCATCGTGGGAACTACGTGAAGGACCTGAGTCGCCTTGGGCGGGAGCTGAGCAAAGTGATCA
TTGTTGACAATTCCCCTGCCTCATACATCTTCCATCCTGAGAATGCAGTGCCTGTGCAGTCCTGGTTCGATGACATGACGGACACGGAGC
TGCTGGACCTCATCCCCTTCTTTGAGGGCCTGAGCCGGGAGGACGACGTGTACAGCATGCTGCACAGACTCTGCAATAGGTAGCCCTGGC
CTCTGCCTGCCTCCCGCCTGTGCACTCTGGAACCTCTGGCCTCAGGGGACCTGCCTGTCCTCAGCTCCCTGGGAGCTGAAAGTGAGGATA
CTCCGTGCTCCAGGCCACAGGGTGAATGTGGCCATGCCTACCTGTTTTGTTTTTTTAAGAACAGAAACAACTATTTTAAAAGAACTCTTT
TAAGAAATTTCATAAAGGGACATGCATTTTACTGGGTTTGCTTTTCTTAAAACATACCAAAAAAGAAAAAAATAGAAAAAAAAAAAAAAA
AAGCTTGATCTCTATCAGACTTCCTTTCAACTGTCCTCCCCTCCAAGCAGACCACCTGTCCCCTTCTATCCCAGCTCAGAGCAGCTGACC
CAACTCAGAATCTCTTTCCTACAGGATGAAGTGCCTTTTGAATGTTATTTTAAGCCGAGAGTTAATTTTTCTACACAACATATTTCCAGA
CATCTTTTAGTCTTTTATTGTCTTAGATACTATAAGAAGATGAACATGACAATTTTCTAGAACCTGGTAGCGTGTGTGTGTGTGGCGGGG
GGTGCTGAGGGAGGGGAGTGAGTCACAGGAGCCTGTCCCCCAACAGGTGTGACTGCTCTGACAACCTGTGGCATGCTGCAGGGTCAGGCT
CCTGATAGGAGGATTTCATGACTATGTCATTGTCTCCACTCATTTTTGACCCAGTTTGGAATGTATCTGCAATTGTGTGGCTCAACACTT
TAGGAAACAATAGATTATTTTATATTATTATTTCTGATGGTGACAAGTTTGTCTTGAGGTCACATTTTCTCCTTGAAAAGTGACATCCTG
TCACTTCTGCTCTCACACTACTGCCATACATTTGTGTTTTTTGTTGTTATTGTTTGGGTAGAGCAGTTACAAGAAACCCTAAAACCCTTG
GATATAAAAGAAATCTGTTTATTGATTTTTAAATCTTTCCTTTCCAAAAGCTGGATACACATGGAGCTGTTTGGGAATTTTCCTTGCTGC
TACCGCGCTGCCACCAAATGGAATTGACCAGCGGCTGTTACACTGTTCTTTGCCACTGTGCCTATGCTCAGAATATGCTCACTGCTAAGC
TACAAACTCGGACAGGGTCAGAAACAGAGGTGTCCCATCCCATTGCAGCCTCCACCACCTGTAACCCCTTCCTGGCATTGGCCACTGAAG
GGTACAAAGGCAAAAGGACCACAGCACCACTTAGGTGTAGCATGGATTTTAAACTGCAGTCAGTATCAGATCCTGTTTGATAAATAAGCT
GACTGTTCTCTCTTGAGAACCTGTGGCCTCAACCAGCCACCAAGCTGATGTGGCCCAAGTCCATCTCTTGGTCTTCTCCTTTGAAGCACA
GCCTATTTCTGAGCCAAGGGTTGGGGAAGCCTGTCTAGATGTGGGACTCATTGCCCCAAACCAGGGAGAGGAAGAGCTCCCACAGGGAGA
GCCCAGGCTCTCTTTGCAGCCTTTCCCAGTTTGGTGTTTAAGCAGTGCCATGTTCCTTGTTTGACAACAAGACAGTCTGTAAAGTATTGC
TCTTAAAAACAATTAAAAAGAACCCTTTCATATTGGCACCATTGCCTTAGTCCTCTGTGGGTTGGTCTTCAGCCAGCATTCTGGTGGGAG
TGACTGGCATTAACAAGACTGGAAATCGGGGGTCAAAGTAAAATATCTTTGTTTTGCTTTCATTCACAAAGTAATGAAGCCAGCTGCCAA
TTACATCCTCCCAACAGCACTTTGGTCTGTGGACTGCTGTGTGAATATTCAGAAGGGAAGTAAGTATTCAGGGGGTAAACAGGTCTCCCA
GCATTCTGAGTGTTCCAAACCAGTAATCCACATGCCAATTCAAATAGAACAGCCCCTTGCTAGATATTACCACAGATAATGACAGTTACA
TGGTAGAACTGCCCATGCCACAAATATTTATTTGGAAAAGTAGTCATTAAATGAACCCACTGCCTTAAATGTCTTGAATGTTGCAGTCAA
GTGTCTGTCATGTGTTGATATCCACACAGAATTAGGCCCTAATGAGAGCCTTAGACCCTCAACCATGCCCCCTTCGTTGGCATCACAGGG
CCTTATTTGGAAGAGCGGGCAAAGAGGATGGAAATCATAAAATATTTCATGGGAATCGAACCTAGGGATAGTGCTCCACTTCTGACGATG
GAGTGAAGACACTTGGCAGACTTGAGCCAGACACTTCACCTAGTAGTTCCTGAAACTGTGAGCACCACTGCACTAAGCCAGTGCGGAGCT
GTTAGGGACGGGCCCAGCTCCTGCACCACGGACACAGAATGTCTGGAGAGGGCCAGCAGGCCCTCTGAGGGTTCTGGAATCTGTGCACCT
TATTTGACCACACTCCAAAATTCTGTTTTTATTTTAACCCTTGAATCTGCTTTATGTACATAATCAAAATATCTATATCTATATCTATAT
CTATATCTATATATTTTTAATCATCTACATGTAAATGAAGCAATAGAATTCTAACATAAGGCCAAGAAATGAGACGAATGTTTGGGGTTT
ATGTTTTTTAAGGTAAATACGGGTATTGTTTTTAATTATTACCATGTATTAAATTGTGGGCTTTGAAACCTAATGAAACCTGTTAGCCAC
TTCTCTGTGCCATATACTTCCCATGTTACCAAAATACCCCCAACTCTTTAGCCAAAAGAGAACCCTGACCTCCTGAGTTTCCATGCTCCT
TTCTGTACCAGGTTTAAATGTAGTCTTCTGGAGAAGTATTTTTGACATTGAGCTCTGGGACAGGACACCTTGGGTTTGTGGACTGCAGCC
CACTATGATGTTATTACTTCTCTGGCCAGGCCTCCAGTGGAAGTGCACAGGCACTCCCAATGTTGTTAATGCTCTGTCTTCCATTTGTTC
TGGAATCCTACGTGTTGGTCTGTGGTTCCATGCATTAGCTGTTTGTAAATAATGCATTTGCATACTGAAAAAGGAATGCCACCTGCCACA
GTTGATGGTGAGGAAGCTCCTTTGACGTGGTGCAATTTTGATGAGATGTCTCTGGGGACACGAGGATGCCCTAATGATGCTGACTTGTCA
TGGTTGCAGCATTTGAACTTTTGGTGTTAAAAAAAAAAACCTGTAAGTCTGTAACCTGGCAACATTTTACAACCCTGTATTTTTAAAGAT
GGCTTTCTAATAAAAAATCCAGAACCACACAGCCCTATGGTCAAACAATCCTACGTTTGTGCCTCTGCTTTTAAAGGTGCTGTGCTGGAC
AGTTGGCATGCCAGGGTTCGAGAAGAGTGAATGGCTTGACGTACTTGCAGTTAACTGTGCAAAATTGGCTGGCTGCCTCTGTTCCTACTG
TACTGTAACTTTGATCATGTCTGTTCCTGTTCCATTCTCCCAGGAGCTTCTCTGCAGACTGACACACCCTCCCCCACCCCGGGTAGTGGA
GATGCTGGTGTCTGGGTAGTCATGGATTTCTGCTGGACATTTGAATGTGATAAACAATCCAGCATTACTTAGGAAATGCTACATGCGGAA

>40464_40464_4_ITGA9-CTDSPL_ITGA9_chr3_37523098_ENST00000422441_CTDSPL_chr3_37988548_ENST00000443503_length(amino acids)=422AA_BP=1
MGMGGPAAPRGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVLVGAPKADSKYSPSVKSPGAVFKCR
VHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSLARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIP
CYEASQCNVSLKKQRSRSILSSFFCCFRDYNVEAPPPSSPSVLPPLVEENGGLQKPPAKYLLPEVTVLDYGKKCVVIDLDETLVHSSFKP
ISNADFIVPVEIDGTIHQVYVLKRPHVDEFLQRMGQLFECVLFTASLAKYADPVADLLDRWGVFRARLFRESCVFHRGNYVKDLSRLGRE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ITGA9-CTDSPL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ITGA9-CTDSPL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ITGA9-CTDSPL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource