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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ITGAV-FAM171B (FusionGDB2 ID:40489)

Fusion Gene Summary for ITGAV-FAM171B

check button Fusion gene summary
Fusion gene informationFusion gene name: ITGAV-FAM171B
Fusion gene ID: 40489
HgeneTgene
Gene symbol

ITGAV

FAM171B

Gene ID

3685

165215

Gene nameintegrin subunit alpha Vfamily with sequence similarity 171 member B
SynonymsCD51|MSK8|VNRA|VTNRKIAA1946
Cytomap

2q32.1

2q32.1

Type of geneprotein-codingprotein-coding
Descriptionintegrin alpha-Vantigen identified by monoclonal antibody L230integrin alphaVbeta3integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)vitronectin receptor subunit alphaprotein FAM171B
Modification date2020031320200313
UniProtAcc

P06756

Q6P995

Ensembl transtripts involved in fusion geneENST00000261023, ENST00000374907, 
ENST00000433736, ENST00000474571, 
ENST00000304698, 
Fusion gene scores* DoF score11 X 9 X 8=7924 X 5 X 4=80
# samples 137
** MAII scorelog2(13/792*10)=-2.60698880705116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/80*10)=-0.192645077942396
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ITGAV [Title/Abstract] AND FAM171B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointITGAV(187498101)-FAM171B(187604955), # samples:1
ITGAV(187466878)-FAM171B(187604955), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneITGAV

GO:0007155

cell adhesion

10218736

HgeneITGAV

GO:0008284

positive regulation of cell proliferation

19578119

HgeneITGAV

GO:0033627

cell adhesion mediated by integrin

12807887|17158881

HgeneITGAV

GO:0034446

substrate adhesion-dependent cell spreading

24658351

HgeneITGAV

GO:0045785

positive regulation of cell adhesion

10708943

HgeneITGAV

GO:0050764

regulation of phagocytosis

10570297

HgeneITGAV

GO:0070588

calcium ion transmembrane transport

18395422

HgeneITGAV

GO:1901388

regulation of transforming growth factor beta activation

22278742

HgeneITGAV

GO:2000536

negative regulation of entry of bacterium into host cell

10570297


check buttonFusion gene breakpoints across ITGAV (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across FAM171B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-CG-4438-01AITGAVchr2

187498101

+FAM171Bchr2

187604955

+
ChimerDB4STADTCGA-MX-A666-01AITGAVchr2

187466878

+FAM171Bchr2

187604955

+


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Fusion Gene ORF analysis for ITGAV-FAM171B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000261023ENST00000304698ITGAVchr2

187498101

+FAM171Bchr2

187604955

+
In-frameENST00000261023ENST00000304698ITGAVchr2

187466878

+FAM171Bchr2

187604955

+
In-frameENST00000374907ENST00000304698ITGAVchr2

187466878

+FAM171Bchr2

187604955

+
In-frameENST00000433736ENST00000304698ITGAVchr2

187498101

+FAM171Bchr2

187604955

+
In-frameENST00000433736ENST00000304698ITGAVchr2

187466878

+FAM171Bchr2

187604955

+
intron-3CDSENST00000374907ENST00000304698ITGAVchr2

187498101

+FAM171Bchr2

187604955

+
intron-3CDSENST00000474571ENST00000304698ITGAVchr2

187498101

+FAM171Bchr2

187604955

+
intron-3CDSENST00000474571ENST00000304698ITGAVchr2

187466878

+FAM171Bchr2

187604955

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000261023ITGAVchr2187498101+ENST00000304698FAM171Bchr2187604955+62839054931471032
ENST00000433736ITGAVchr2187498101+ENST00000304698FAM171Bchr2187604955+60016231302865911
ENST00000261023ITGAVchr2187466878+ENST00000304698FAM171Bchr2187604955+5968590492832927
ENST00000374907ITGAVchr2187466878+ENST00000304698FAM171Bchr2187604955+5953575342817927
ENST00000433736ITGAVchr2187466878+ENST00000304698FAM171Bchr2187604955+56863081302550806

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000261023ENST00000304698ITGAVchr2187498101+FAM171Bchr2187604955+0.0001294780.99987054
ENST00000433736ENST00000304698ITGAVchr2187498101+FAM171Bchr2187604955+3.85E-050.9999615
ENST00000261023ENST00000304698ITGAVchr2187466878+FAM171Bchr2187604955+0.0003026510.9996973
ENST00000374907ENST00000304698ITGAVchr2187466878+FAM171Bchr2187604955+0.0003025770.99969745
ENST00000433736ENST00000304698ITGAVchr2187466878+FAM171Bchr2187604955+6.95E-050.9999305

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Fusion Genomic Features for ITGAV-FAM171B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ITGAVchr2187466878+FAM171Bchr2187604954+0.0001388680.9998611
ITGAVchr2187498101+FAM171Bchr2187604954+2.23E-050.9999777
ITGAVchr2187466878+FAM171Bchr2187604954+0.0001388680.9998611
ITGAVchr2187498101+FAM171Bchr2187604954+2.23E-050.9999777

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ITGAV-FAM171B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:187498101/chr2:187604955)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ITGAV

P06756

FAM171B

Q6P995

FUNCTION: The alpha-V (ITGAV) integrins are receptors for vitronectin, cytotactin, fibronectin, fibrinogen, laminin, matrix metalloproteinase-2, osteopontin, osteomodulin, prothrombin, thrombospondin and vWF. They recognize the sequence R-G-D in a wide array of ligands. ITGAV:ITGB3 binds to fractalkine (CX3CL1) and may act as its coreceptor in CX3CR1-dependent fractalkine signaling (PubMed:23125415). ITGAV:ITGB3 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGAV:ITGB3 binds to FGF1 and this binding is essential for FGF1 signaling (PubMed:18441324). ITGAV:ITGB3 binds to FGF2 and this binding is essential for FGF2 signaling (PubMed:28302677). ITGAV:ITGB3 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:19578119). ITGAV:ITGB3 binds to IGF2 and this binding is essential for IGF2 signaling (PubMed:28873464). ITGAV:ITGB3 binds to IL1B and this binding is essential for IL1B signaling (PubMed:29030430). ITGAV:ITGB3 binds to PLA2G2A via a site (site 2) which is distinct from the classical ligand-binding site (site 1) and this induces integrin conformational changes and enhanced ligand binding to site 1 (PubMed:18635536, PubMed:25398877). ITGAV:ITGB3 and ITGAV:ITGB6 act as a receptor for fibrillin-1 (FBN1) and mediate R-G-D-dependent cell adhesion to FBN1 (PubMed:12807887, PubMed:17158881). Integrin alpha-V/beta-6 or alpha-V/beta-8 (ITGAV:ITGB6 or ITGAV:ITGB8) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation (PubMed:15184403, PubMed:22278742, PubMed:28117447). ITGAV:ITGB3 act as a receptor for CD40LG (PubMed:31331973). {ECO:0000269|PubMed:12807887, ECO:0000269|PubMed:15184403, ECO:0000269|PubMed:17158881, ECO:0000269|PubMed:18441324, ECO:0000269|PubMed:18635536, ECO:0000269|PubMed:19578119, ECO:0000269|PubMed:20682778, ECO:0000269|PubMed:22278742, ECO:0000269|PubMed:23125415, ECO:0000269|PubMed:25398877, ECO:0000269|PubMed:28117447, ECO:0000269|PubMed:28302677, ECO:0000269|PubMed:28873464, ECO:0000269|PubMed:29030430, ECO:0000269|PubMed:31331973}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB5 acts as a receptor for Adenovirus type C. {ECO:0000269|PubMed:20615244}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB5 and ITGAV:ITGB3 act as receptors for Coxsackievirus A9 and B1. {ECO:0000269|PubMed:15194773, ECO:0000269|PubMed:7519807, ECO:0000269|PubMed:9426447}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB3 acts as a receptor for Herpes virus 8/HHV-8. {ECO:0000269|PubMed:18045938}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB6 acts as a receptor for herpes simplex 1/HHV-1. {ECO:0000269|PubMed:24367260}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB3 acts as a receptor for Human parechovirus 1. {ECO:0000269|PubMed:11160695}.; FUNCTION: (Microbial infection) Integrin ITGAV:ITGB3 acts as a receptor for West nile virus. {ECO:0000269|PubMed:23658209}.; FUNCTION: (Microbial infection) In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions. {ECO:0000269|PubMed:10397733}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+23032_981051049.0RepeatFG-GAP 1
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+22832_981051013.0RepeatFG-GAP 1
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630109_1702101049.0RepeatFG-GAP 2
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+63032_982101049.0RepeatFG-GAP 1
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+63032_981641003.0RepeatFG-GAP 1
TgeneFAM171Bchr2:187466878chr2:187604955ENST0000030469808375_82679827.0Topological domainCytoplasmic
TgeneFAM171Bchr2:187498101chr2:187604955ENST0000030469808375_82679827.0Topological domainCytoplasmic
TgeneFAM171Bchr2:187466878chr2:187604955ENST0000030469808354_37479827.0TransmembraneHelical
TgeneFAM171Bchr2:187498101chr2:187604955ENST0000030469808354_37479827.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230260_2681051049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230314_3221051049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230379_3871051049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230443_4511051049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228260_2681051013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228314_3221051013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228379_3871051013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228443_4511051013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230260_268591003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230314_322591003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230379_387591003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230443_451591003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630260_2682101049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630314_3222101049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630379_3872101049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630443_4512101049.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128260_26801013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128314_32201013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128379_38701013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128443_45101013.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630260_2681641003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630314_3221641003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630379_3871641003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630443_4511641003.0Calcium bindingOntology_term=ECO:0000255,ECO:0000269
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+2301019_10231051049.0MotifNote=GFFKR motif
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+2281019_10231051013.0MotifNote=GFFKR motif
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+2301019_1023591003.0MotifNote=GFFKR motif
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+6301019_10232101049.0MotifNote=GFFKR motif
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+1281019_102301013.0MotifNote=GFFKR motif
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+6301019_10231641003.0MotifNote=GFFKR motif
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230109_1701051049.0RepeatFG-GAP 2
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230173_2251051049.0RepeatFG-GAP 3
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230237_2911051049.0RepeatFG-GAP 4
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230292_3571051049.0RepeatFG-GAP 5
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230358_4151051049.0RepeatFG-GAP 6
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230419_4821051049.0RepeatFG-GAP 7
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228109_1701051013.0RepeatFG-GAP 2
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228173_2251051013.0RepeatFG-GAP 3
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228237_2911051013.0RepeatFG-GAP 4
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228292_3571051013.0RepeatFG-GAP 5
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228358_4151051013.0RepeatFG-GAP 6
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228419_4821051013.0RepeatFG-GAP 7
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230109_170591003.0RepeatFG-GAP 2
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230173_225591003.0RepeatFG-GAP 3
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230237_291591003.0RepeatFG-GAP 4
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230292_357591003.0RepeatFG-GAP 5
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+23032_98591003.0RepeatFG-GAP 1
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230358_415591003.0RepeatFG-GAP 6
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230419_482591003.0RepeatFG-GAP 7
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630173_2252101049.0RepeatFG-GAP 3
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630237_2912101049.0RepeatFG-GAP 4
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630292_3572101049.0RepeatFG-GAP 5
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630358_4152101049.0RepeatFG-GAP 6
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630419_4822101049.0RepeatFG-GAP 7
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128109_17001013.0RepeatFG-GAP 2
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128173_22501013.0RepeatFG-GAP 3
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128237_29101013.0RepeatFG-GAP 4
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128292_35701013.0RepeatFG-GAP 5
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+12832_9801013.0RepeatFG-GAP 1
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128358_41501013.0RepeatFG-GAP 6
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128419_48201013.0RepeatFG-GAP 7
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630109_1701641003.0RepeatFG-GAP 2
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630173_2251641003.0RepeatFG-GAP 3
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630237_2911641003.0RepeatFG-GAP 4
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630292_3571641003.0RepeatFG-GAP 5
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630358_4151641003.0RepeatFG-GAP 6
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630419_4821641003.0RepeatFG-GAP 7
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+2301017_10481051049.0Topological domainCytoplasmic
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+23031_9921051049.0Topological domainExtracellular
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+2281017_10481051013.0Topological domainCytoplasmic
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+22831_9921051013.0Topological domainExtracellular
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+2301017_1048591003.0Topological domainCytoplasmic
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+23031_992591003.0Topological domainExtracellular
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+6301017_10482101049.0Topological domainCytoplasmic
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+63031_9922101049.0Topological domainExtracellular
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+1281017_104801013.0Topological domainCytoplasmic
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+12831_99201013.0Topological domainExtracellular
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+6301017_10481641003.0Topological domainCytoplasmic
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+63031_9921641003.0Topological domainExtracellular
HgeneITGAVchr2:187466878chr2:187604955ENST00000261023+230993_10161051049.0TransmembraneHelical
HgeneITGAVchr2:187466878chr2:187604955ENST00000374907+228993_10161051013.0TransmembraneHelical
HgeneITGAVchr2:187466878chr2:187604955ENST00000433736+230993_1016591003.0TransmembraneHelical
HgeneITGAVchr2:187498101chr2:187604955ENST00000261023+630993_10162101049.0TransmembraneHelical
HgeneITGAVchr2:187498101chr2:187604955ENST00000374907+128993_101601013.0TransmembraneHelical
HgeneITGAVchr2:187498101chr2:187604955ENST00000433736+630993_10161641003.0TransmembraneHelical
TgeneFAM171Bchr2:187466878chr2:187604955ENST000003046980843_5879827.0Compositional biasNote=Gln-rich
TgeneFAM171Bchr2:187498101chr2:187604955ENST000003046980843_5879827.0Compositional biasNote=Gln-rich
TgeneFAM171Bchr2:187466878chr2:187604955ENST000003046980833_35379827.0Topological domainExtracellular
TgeneFAM171Bchr2:187498101chr2:187604955ENST000003046980833_35379827.0Topological domainExtracellular


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Fusion Gene Sequence for ITGAV-FAM171B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>40489_40489_1_ITGAV-FAM171B_ITGAV_chr2_187466878_ENST00000261023_FAM171B_chr2_187604955_ENST00000304698_length(transcript)=5968nt_BP=590nt
CCTCAGACGCTGCGTGGAGCGGCGGAGCCGGAGGGAAGCAAAGGACCGTCTGCGCTGCTGTCCCCGCCCCGCGCGCTCTGCGCCCCTCGT
CCCTGGCGGTCGCTCCGAAGCTCAGCCCTCTTGCCTGCCCCGGAGCTGTCCCGGGCTAGCCGAGAAGAGAGCGGCCGGCAAGTTTGGGCG
CGCGCAGGCGGCGGGCCGCGGGCACTGGGCGCCTCGCTGGGGCGGGGGGAGGTGGCTACCGCTCCCGGCTTGGCGTCCCGCGCGCACTTC
GGCGATGGCTTTTCCGCCGCGGCGACGGCTGCGCCTCGGTCCCCGCGGCCTCCCGCTTCTTCTCTCGGGACTCCTGCTACCTCTGTGCCG
CGCCTTCAACCTAGACGTGGACAGTCCTGCCGAGTACTCTGGCCCCGAGGGAAGTTACTTCGGCTTCGCCGTGGATTTCTTCGTGCCCAG
CGCGTCTTCCCGGATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATG
TGACTGGTCTTCTACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGTGTCTGTATTTATGTTGAAAGTCCAGGTGAATGACATCAT
CAGTCGTCAGTACCTGAGCCAAGCAGTTGTAGAAGTGTTTGTAAACTACACGAAGACAAATTCCACAGTAACTAAAAGCAATGGAGCAGT
GCTGATAAAAGTACCCTACAAATTAGGACTTAGTTTAACTATTATTGCTTACAAAGATGGCTACGTGTTGACCCCTCTGCCTTGGAAAAC
CAGAAGAATGCCAATATATTCATCAGTTACACTTTCACTGTTCCCGCAAAGCCAAGCAAATATATGGCTATTTGAAGACACTGTTTTAAT
TACTGGAAAATTAGCTGATGCCAAGTCTCAACCAAGTGTTCAGTTTTCAAAAGCCTTAATTAAACTTCCTGACAACCATCATATTAGCAA
CGTTACTGGCTATCTTACAGTTCTACAACAGTTTTTGAAAGTGGACAATTTTCTGCATACAACTGGAATTACTCTCAATAAACCAGGTTT
TGAAAACATTGAATTGACTCCTCTTGCTGCAATATGTGTGAAAATATATTCTGGAGGAAAAGAACTAAAGGTCAATGGCTCTATTCAAGT
TTCTCTTCCTCTTCTACGTCTGAATGATATAAGTGCAGGGGATCGCATACCTGCTTGGACATTTGATATGAACACAGGTGCTTGGGTAAA
TCATGGTCGGGGAATGGTCAAGGAACATAACAATCATTTAATCTGGACATATGATGCACCACATTTGGGGTACTGGATAGCAGCTCCACT
TCCAGGAACTAGAGGTTCAGGTATAAATGAAGATTCCAAGGACATAACTGCCTACCACACAGTGTTTCTTACAGCCATATTAGGAGGAAC
AATAGTCATTGTCATTGGATTTTTTGCTGTACTACTTTGTTATTGCAGGGACAAGTGTGGTACTCCACAGAAAAGAGAAAGAAATATCAC
TAAACTTGAGGTCCTCAAGAGAGACCAGACAACTTCAACAACACACATAAATCATATCAGTACAGTTAAAGTTGCATTAAAAGCTGAGGA
CAAGTCGCAGTTATTCAATGCCAAAAACTCCTCATATAGTCCTCAGAAAAAGGAACCATCAAAGGCAGAAACAGAAGAAAGAGTTTCCAT
GGTAAAAACTCGGGACGATTTTAAAATCTACAATGAAGATGTTTCATTTCTATCAGTCAATCAAAATAATTACTCAAGAAACCCAACACA
GTCTTTGGAGCCCAATGTAGGGTCCAAACAACCTAAACATATTAACAACAATCTATCTTCATCTCTAGGTGATGCTCAAGATGAAAAGAG
GTATCTCACAGGTAATGAGGAGGCGTATGGGCGTTCCCATATTCCTGAACAGCTTATGCATATTTACAGCCAACCCATTGCCATCCTTCA
AACATCTGACCTTTTCTCCACACCGGAACAATTACATACTGCTAAGTCAGCTACTTTGCCAAGAAAGGGACAGTTAGTCTATGGCCAATT
GATGGAACCAGTAAATCGAGAGAACTTTACGCAGACCTTGCCCAAAATGCCAATTCATTCTCATGCACAGCCCCCAGATGCCAGGGAAGA
GGATATCATACTTGAAGGTCAACAGAGCCTGCCATCCCAGGCTTCAGATTGGAGCCGATACTCAAGCAGCTTACTGGAATCCGTCTCTGT
TCCTGGAACACTAAATGAGGCTGTTGTAATGACTCCATTTTCATCGGAACTTCAAGGAATTTCAGAACAGACCCTCCTGGAGCTGTCCAA
AGGAAAGCCCTCCCCGCATCCCAGAGCCTGGTTTGTGTCTCTTGATGGAAAGCCAGTTGCACAAGTGAGGCACTCCTTTATAGACCTGAA
AAAGGGCAAGAGAACCCAGAGCAATGACACCAGTCTGGACTCTGGGGTGGACATGAATGAGCTTCACTCAAGTAGAAAGCTCGAGAGGGA
GAAAACATTCATCAAAAGCATGCATCAGCCCAAGATCCTTTACTTAGAAGATTTAGACCTAAGCAGCAGTGAGAGTGGAACCACCGTCTG
TTCCCCTGAGGACCCAGCTTTAAGGCACATCCTAGATGGAGGGAGTGGAGTGATCATGGAGCACCCTGGAGAAGAGTCGCCAGGAAGGAA
AAGCACTGTTGAAGATTTTGAAGCTAATACATCCCCCACTAAAAGAAGGGGCAGACCACCACTAGCCAAAAGAGATAGCAAGACTAACAT
CTGGAAGAAGCGAGAGGAACGCCCACTGATTCCCATAAATTAACTCCAATGGGGATTGTGTGTCTGCTGTCTCGTGCTGTTTATTCTTGC
TTCTTGTTGTAAATTGCAGTACGAACTTAAGAAAATGAGACTGAGCAATCTCATGGTTCTTGGACATGTCTCAAGCAGAGTAAATGGTAA
TTCAGTAATCAGAGAGAAAGATACCAAGGAATGCTTTTTCTGGCCTATTCATTTATTTTTGGGTGATGAATTTACAGTATCTAAGTTTTC
AAAATGTAAAATAGCTTCAAGATGTTAGTTATCTGAAAATGTTGCTCAGCCAGCCAGTTTGGCCTTGACTCTCTTAAGAATAACAGTGAA
ATATATACTCCTCAAGTTGCCTCCAAAAATGTTGCCTCTACCATGGTGACTACCCCATGGAACATTTAGAAACAAAACTGACTTCAGGCA
TCATATTATTTTAAATGTTACTATTACGTCTTCTTCTGCCTATACTTAAAAATAACTTGATAAATGACTTGGACTGATGTTACTCTGGAG
TTATCACAAAGAAAATGTTGTTTGGTCTTTAAAGAGCATGTGTATTGTATCATCCCAAACGTAAATCCTACATTTATATAAGATGGGCAA
GAAGCTACTTGGTCATTAGAGAGGGAGACACCAGCTCTTTGGTTGTTTTTGGATATAACTTTACAAAATAAGTAAGATGTTAATTTAGAA
ATTTGAGAAATTAATGCTCTAATACTGAGTTTTTATTTAAAAATTATTTTTTCTTCCCCTCAACAATGAAGCAAGCTTAGCTGTCAAGGG
AAACTTTTTACAAATCTGAAAAAAACAATCTATGACTTTGGTTTAAGGCTCACTGATACTTTTAGGCTAAATTGGTTTTAATATATTTCT
TCTATTCTAAAAACCTGAACTCAGTCACTTAAAGGCTATGAAATTTAAAAAAAAAGTCGATGTGAAAGTTTCTTTTGAACACTAAAATAA
AATATGTGCAGATAAAATATACATTGATTTGTTTTTCTTAAATGTTGATGAGAAGAAAAAGAGATGCCATTTTCCTGAGGCTCAAAAATA
CCTTCAGGATAGTTGTATATCCAGTTATTGATTTTCTTAAAAGATGTGTAAGGAAAACAGTTTCAATTTCAGGGGAAAAGTAAAAGTTTT
TCCCTAAGTCACTTAAAGCCTTTGCAACTTCTTTTTTCAGTTTTGTAAGTAATATATCTATGTTCTTTTCATTATAGCAAGCATTCAATG
TGAACAACTTTTTAATTAACTCTGAATTACCATTCATACATCCTAAAAATAAAAGCTCGTTATTCATTAAAATCAACTGATCCCATTTTT
CTTAAAATTTCCCTGAAGGCAAATGTCTGAAGCACCTTTCCCTTGTGGGGGTAAAAATCCTAAATTGCTTTATTTTTCATTCCCTCCTAT
TCAACATGGGAGCAGCATAGAGACCCAAACCATGTAAACAAGTTCAGTGAACCAAAACAGCCACATTAGCTTCAGTAAAATTATAGCTAG
ATGTGCAATTTTTTCCTCCAACTTCTAACGTGTCAAATAACCTTCCTACTGTTCTGTGTTAACTGAAAGAACATAAAGACCCTAGGCAAA
TATTTGCTATATATTACCCCAATCCATAGAAGAAATAATGTTTTGGGTAATACCTAGGCTTCCTTTTTTTTTTTTTTTTTTTTTTTTTAG
TGATAAGGCTCATAACAATTAATTAGAGAAGGCTTCTTATTGGTCTTACACAGAAAGATACATCAAAAGCAGCATGACTCAAAATGATTT
GGAAAAGGTTAAAGTTAGTGCTCTGCTGAAGTGCCTTTGATATAGACTTGCATTATTAGAAGGATATAACATCTTTTTTAAGTGTGCATT
TTCTTTCAGTTAACCAAATTAAACAGATGTGCAGTTTTATTAAAAATATAGACCTAGTGTTTCATGTTGGAACAATAAATATTGCATGTG
AGTAGTATTTCTTGTTTTTTGAATACAGTATATATTGATAAATTGTTTATGTTGGAATGAAGTTAGAAACTATATAGCAAAACATTATAT
TTTAAGTGTTTATTTTTCCCACCTTTAAATAAAAATGTTTCATCTCAGCTTGGTAATGAAATACACATATTGGTATAAGGGTATACCATT
CAGGTATGCCACTTATTTTATTCATTTTTGTGTAAGGGAAATGAGATGATGTATCCCAAGGGCTTTTCTAGAACTACTTGTTTGCTTTCA
GAATAAAACCTTATTATTTTTTACACTGCACATGCTGTTCTCAATTGGTAATTATAGGCAATTTATCTTTTCTAATGATCAAAAGAGTGT
GACTTCTCATTTGTGAGTAGTTCACAAATTTCCTGTTAAAAAGCTGAAACCATCTACTTTTTCTTAACCCAAGTGATAATAAACAATATT
CACAACTTTCTTAAATTTTTAAATTGAAAACCAAGGTTTTTTCAAATATAAACCTAGATGATTTTGGTCACAAATTGTTAACATTTGTCG
ATCCTTTGTATATACTTTGGATATATATTAAAGGCAAAACTATCTCTTGACTAACTGATGGATTCATTTACTAAAGCACAGCTGTATGTA
TTTTTGAATACATATTATGATCTTGAGACTTTATAAATCAATTTTTATGACTTTATGCAGTTGTATAGGGATTATGCCCTTTCAGTTCTA
TAGGGATTATGCCCTTTTATAATACATAATATACCACAGAGATTACAAATGTTGAGGAATGAAAGCACTTCTTTGCTTTGGCAATCATTT
TCAGACCACTATGTGTTTGAATCCTCTGGTATCAATACGTATTATAGGGTTTTAGAGATCTGTGGGTCAAATGATGTCCCTCAAAACTTC
CTAAAAAGGTGAAGCTCAAAGTCACACATTCTTATAAGGCGCATGAGTTTCTCATTTTCCCATGTACGAGCATTGTAAAGGAATTCAGCT
GTATTAATTTCTATTTCAGATCTAGAATTGACATTTTGCCTTCTTGTTTCCAGGTGTTTCTATTTTTTGTATTCTTTCAGAGAAATCTCA
TATTTCGGTGTATTTATTGCTGTTACTACTATATTTACTGCTGAAAACTGTAACAACCTGAAGATTTGTAAAATGTTAAACATAGTTCAT

>40489_40489_1_ITGAV-FAM171B_ITGAV_chr2_187466878_ENST00000261023_FAM171B_chr2_187604955_ENST00000304698_length(amino acids)=927AA_BP=1
MRCCPRPARSAPLVPGGRSEAQPSCLPRSCPGLAEKRAAGKFGRAQAAGRGHWAPRWGGGRWLPLPAWRPARTSAMAFPPRRRLRLGPRG
LPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDAT
VSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQ
SQANIWLFEDTVLITGKLADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFENIELTPLAAICVKIY
SGGKELKVNGSIQVSLPLLRLNDISAGDRIPAWTFDMNTGAWVNHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRGSGINEDSKDIT
AYHTVFLTAILGGTIVIVIGFFAVLLCYCRDKCGTPQKRERNITKLEVLKRDQTTSTTHINHISTVKVALKAEDKSQLFNAKNSSYSPQK
KEPSKAETEERVSMVKTRDDFKIYNEDVSFLSVNQNNYSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPE
QLMHIYSQPIAILQTSDLFSTPEQLHTAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPIHSHAQPPDAREEDIILEGQQSLPSQASD
WSRYSSSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGV
DMNELHSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGSGVIMEHPGEESPGRKSTVEDFEANTSPTKRR

--------------------------------------------------------------
>40489_40489_2_ITGAV-FAM171B_ITGAV_chr2_187466878_ENST00000374907_FAM171B_chr2_187604955_ENST00000304698_length(transcript)=5953nt_BP=575nt
GGAGCGGCGGAGCCGGAGGGAAGCAAAGGACCGTCTGCGCTGCTGTCCCCGCCCCGCGCGCTCTGCGCCCCTCGTCCCTGGCGGTCGCTC
CGAAGCTCAGCCCTCTTGCCTGCCCCGGAGCTGTCCCGGGCTAGCCGAGAAGAGAGCGGCCGGCAAGTTTGGGCGCGCGCAGGCGGCGGG
CCGCGGGCACTGGGCGCCTCGCTGGGGCGGGGGGAGGTGGCTACCGCTCCCGGCTTGGCGTCCCGCGCGCACTTCGGCGATGGCTTTTCC
GCCGCGGCGACGGCTGCGCCTCGGTCCCCGCGGCCTCCCGCTTCTTCTCTCGGGACTCCTGCTACCTCTGTGCCGCGCCTTCAACCTAGA
CGTGGACAGTCCTGCCGAGTACTCTGGCCCCGAGGGAAGTTACTTCGGCTTCGCCGTGGATTTCTTCGTGCCCAGCGCGTCTTCCCGGAT
GTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTCTAC
CCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGTGTCTGTATTTATGTTGAAAGTCCAGGTGAATGACATCATCAGTCGTCAGTACCT
GAGCCAAGCAGTTGTAGAAGTGTTTGTAAACTACACGAAGACAAATTCCACAGTAACTAAAAGCAATGGAGCAGTGCTGATAAAAGTACC
CTACAAATTAGGACTTAGTTTAACTATTATTGCTTACAAAGATGGCTACGTGTTGACCCCTCTGCCTTGGAAAACCAGAAGAATGCCAAT
ATATTCATCAGTTACACTTTCACTGTTCCCGCAAAGCCAAGCAAATATATGGCTATTTGAAGACACTGTTTTAATTACTGGAAAATTAGC
TGATGCCAAGTCTCAACCAAGTGTTCAGTTTTCAAAAGCCTTAATTAAACTTCCTGACAACCATCATATTAGCAACGTTACTGGCTATCT
TACAGTTCTACAACAGTTTTTGAAAGTGGACAATTTTCTGCATACAACTGGAATTACTCTCAATAAACCAGGTTTTGAAAACATTGAATT
GACTCCTCTTGCTGCAATATGTGTGAAAATATATTCTGGAGGAAAAGAACTAAAGGTCAATGGCTCTATTCAAGTTTCTCTTCCTCTTCT
ACGTCTGAATGATATAAGTGCAGGGGATCGCATACCTGCTTGGACATTTGATATGAACACAGGTGCTTGGGTAAATCATGGTCGGGGAAT
GGTCAAGGAACATAACAATCATTTAATCTGGACATATGATGCACCACATTTGGGGTACTGGATAGCAGCTCCACTTCCAGGAACTAGAGG
TTCAGGTATAAATGAAGATTCCAAGGACATAACTGCCTACCACACAGTGTTTCTTACAGCCATATTAGGAGGAACAATAGTCATTGTCAT
TGGATTTTTTGCTGTACTACTTTGTTATTGCAGGGACAAGTGTGGTACTCCACAGAAAAGAGAAAGAAATATCACTAAACTTGAGGTCCT
CAAGAGAGACCAGACAACTTCAACAACACACATAAATCATATCAGTACAGTTAAAGTTGCATTAAAAGCTGAGGACAAGTCGCAGTTATT
CAATGCCAAAAACTCCTCATATAGTCCTCAGAAAAAGGAACCATCAAAGGCAGAAACAGAAGAAAGAGTTTCCATGGTAAAAACTCGGGA
CGATTTTAAAATCTACAATGAAGATGTTTCATTTCTATCAGTCAATCAAAATAATTACTCAAGAAACCCAACACAGTCTTTGGAGCCCAA
TGTAGGGTCCAAACAACCTAAACATATTAACAACAATCTATCTTCATCTCTAGGTGATGCTCAAGATGAAAAGAGGTATCTCACAGGTAA
TGAGGAGGCGTATGGGCGTTCCCATATTCCTGAACAGCTTATGCATATTTACAGCCAACCCATTGCCATCCTTCAAACATCTGACCTTTT
CTCCACACCGGAACAATTACATACTGCTAAGTCAGCTACTTTGCCAAGAAAGGGACAGTTAGTCTATGGCCAATTGATGGAACCAGTAAA
TCGAGAGAACTTTACGCAGACCTTGCCCAAAATGCCAATTCATTCTCATGCACAGCCCCCAGATGCCAGGGAAGAGGATATCATACTTGA
AGGTCAACAGAGCCTGCCATCCCAGGCTTCAGATTGGAGCCGATACTCAAGCAGCTTACTGGAATCCGTCTCTGTTCCTGGAACACTAAA
TGAGGCTGTTGTAATGACTCCATTTTCATCGGAACTTCAAGGAATTTCAGAACAGACCCTCCTGGAGCTGTCCAAAGGAAAGCCCTCCCC
GCATCCCAGAGCCTGGTTTGTGTCTCTTGATGGAAAGCCAGTTGCACAAGTGAGGCACTCCTTTATAGACCTGAAAAAGGGCAAGAGAAC
CCAGAGCAATGACACCAGTCTGGACTCTGGGGTGGACATGAATGAGCTTCACTCAAGTAGAAAGCTCGAGAGGGAGAAAACATTCATCAA
AAGCATGCATCAGCCCAAGATCCTTTACTTAGAAGATTTAGACCTAAGCAGCAGTGAGAGTGGAACCACCGTCTGTTCCCCTGAGGACCC
AGCTTTAAGGCACATCCTAGATGGAGGGAGTGGAGTGATCATGGAGCACCCTGGAGAAGAGTCGCCAGGAAGGAAAAGCACTGTTGAAGA
TTTTGAAGCTAATACATCCCCCACTAAAAGAAGGGGCAGACCACCACTAGCCAAAAGAGATAGCAAGACTAACATCTGGAAGAAGCGAGA
GGAACGCCCACTGATTCCCATAAATTAACTCCAATGGGGATTGTGTGTCTGCTGTCTCGTGCTGTTTATTCTTGCTTCTTGTTGTAAATT
GCAGTACGAACTTAAGAAAATGAGACTGAGCAATCTCATGGTTCTTGGACATGTCTCAAGCAGAGTAAATGGTAATTCAGTAATCAGAGA
GAAAGATACCAAGGAATGCTTTTTCTGGCCTATTCATTTATTTTTGGGTGATGAATTTACAGTATCTAAGTTTTCAAAATGTAAAATAGC
TTCAAGATGTTAGTTATCTGAAAATGTTGCTCAGCCAGCCAGTTTGGCCTTGACTCTCTTAAGAATAACAGTGAAATATATACTCCTCAA
GTTGCCTCCAAAAATGTTGCCTCTACCATGGTGACTACCCCATGGAACATTTAGAAACAAAACTGACTTCAGGCATCATATTATTTTAAA
TGTTACTATTACGTCTTCTTCTGCCTATACTTAAAAATAACTTGATAAATGACTTGGACTGATGTTACTCTGGAGTTATCACAAAGAAAA
TGTTGTTTGGTCTTTAAAGAGCATGTGTATTGTATCATCCCAAACGTAAATCCTACATTTATATAAGATGGGCAAGAAGCTACTTGGTCA
TTAGAGAGGGAGACACCAGCTCTTTGGTTGTTTTTGGATATAACTTTACAAAATAAGTAAGATGTTAATTTAGAAATTTGAGAAATTAAT
GCTCTAATACTGAGTTTTTATTTAAAAATTATTTTTTCTTCCCCTCAACAATGAAGCAAGCTTAGCTGTCAAGGGAAACTTTTTACAAAT
CTGAAAAAAACAATCTATGACTTTGGTTTAAGGCTCACTGATACTTTTAGGCTAAATTGGTTTTAATATATTTCTTCTATTCTAAAAACC
TGAACTCAGTCACTTAAAGGCTATGAAATTTAAAAAAAAAGTCGATGTGAAAGTTTCTTTTGAACACTAAAATAAAATATGTGCAGATAA
AATATACATTGATTTGTTTTTCTTAAATGTTGATGAGAAGAAAAAGAGATGCCATTTTCCTGAGGCTCAAAAATACCTTCAGGATAGTTG
TATATCCAGTTATTGATTTTCTTAAAAGATGTGTAAGGAAAACAGTTTCAATTTCAGGGGAAAAGTAAAAGTTTTTCCCTAAGTCACTTA
AAGCCTTTGCAACTTCTTTTTTCAGTTTTGTAAGTAATATATCTATGTTCTTTTCATTATAGCAAGCATTCAATGTGAACAACTTTTTAA
TTAACTCTGAATTACCATTCATACATCCTAAAAATAAAAGCTCGTTATTCATTAAAATCAACTGATCCCATTTTTCTTAAAATTTCCCTG
AAGGCAAATGTCTGAAGCACCTTTCCCTTGTGGGGGTAAAAATCCTAAATTGCTTTATTTTTCATTCCCTCCTATTCAACATGGGAGCAG
CATAGAGACCCAAACCATGTAAACAAGTTCAGTGAACCAAAACAGCCACATTAGCTTCAGTAAAATTATAGCTAGATGTGCAATTTTTTC
CTCCAACTTCTAACGTGTCAAATAACCTTCCTACTGTTCTGTGTTAACTGAAAGAACATAAAGACCCTAGGCAAATATTTGCTATATATT
ACCCCAATCCATAGAAGAAATAATGTTTTGGGTAATACCTAGGCTTCCTTTTTTTTTTTTTTTTTTTTTTTTTAGTGATAAGGCTCATAA
CAATTAATTAGAGAAGGCTTCTTATTGGTCTTACACAGAAAGATACATCAAAAGCAGCATGACTCAAAATGATTTGGAAAAGGTTAAAGT
TAGTGCTCTGCTGAAGTGCCTTTGATATAGACTTGCATTATTAGAAGGATATAACATCTTTTTTAAGTGTGCATTTTCTTTCAGTTAACC
AAATTAAACAGATGTGCAGTTTTATTAAAAATATAGACCTAGTGTTTCATGTTGGAACAATAAATATTGCATGTGAGTAGTATTTCTTGT
TTTTTGAATACAGTATATATTGATAAATTGTTTATGTTGGAATGAAGTTAGAAACTATATAGCAAAACATTATATTTTAAGTGTTTATTT
TTCCCACCTTTAAATAAAAATGTTTCATCTCAGCTTGGTAATGAAATACACATATTGGTATAAGGGTATACCATTCAGGTATGCCACTTA
TTTTATTCATTTTTGTGTAAGGGAAATGAGATGATGTATCCCAAGGGCTTTTCTAGAACTACTTGTTTGCTTTCAGAATAAAACCTTATT
ATTTTTTACACTGCACATGCTGTTCTCAATTGGTAATTATAGGCAATTTATCTTTTCTAATGATCAAAAGAGTGTGACTTCTCATTTGTG
AGTAGTTCACAAATTTCCTGTTAAAAAGCTGAAACCATCTACTTTTTCTTAACCCAAGTGATAATAAACAATATTCACAACTTTCTTAAA
TTTTTAAATTGAAAACCAAGGTTTTTTCAAATATAAACCTAGATGATTTTGGTCACAAATTGTTAACATTTGTCGATCCTTTGTATATAC
TTTGGATATATATTAAAGGCAAAACTATCTCTTGACTAACTGATGGATTCATTTACTAAAGCACAGCTGTATGTATTTTTGAATACATAT
TATGATCTTGAGACTTTATAAATCAATTTTTATGACTTTATGCAGTTGTATAGGGATTATGCCCTTTCAGTTCTATAGGGATTATGCCCT
TTTATAATACATAATATACCACAGAGATTACAAATGTTGAGGAATGAAAGCACTTCTTTGCTTTGGCAATCATTTTCAGACCACTATGTG
TTTGAATCCTCTGGTATCAATACGTATTATAGGGTTTTAGAGATCTGTGGGTCAAATGATGTCCCTCAAAACTTCCTAAAAAGGTGAAGC
TCAAAGTCACACATTCTTATAAGGCGCATGAGTTTCTCATTTTCCCATGTACGAGCATTGTAAAGGAATTCAGCTGTATTAATTTCTATT
TCAGATCTAGAATTGACATTTTGCCTTCTTGTTTCCAGGTGTTTCTATTTTTTGTATTCTTTCAGAGAAATCTCATATTTCGGTGTATTT
ATTGCTGTTACTACTATATTTACTGCTGAAAACTGTAACAACCTGAAGATTTGTAAAATGTTAAACATAGTTCATTAAAAATAATAAAAT

>40489_40489_2_ITGAV-FAM171B_ITGAV_chr2_187466878_ENST00000374907_FAM171B_chr2_187604955_ENST00000304698_length(amino acids)=927AA_BP=1
MRCCPRPARSAPLVPGGRSEAQPSCLPRSCPGLAEKRAAGKFGRAQAAGRGHWAPRWGGGRWLPLPAWRPARTSAMAFPPRRRLRLGPRG
LPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDAT
VSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQ
SQANIWLFEDTVLITGKLADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFENIELTPLAAICVKIY
SGGKELKVNGSIQVSLPLLRLNDISAGDRIPAWTFDMNTGAWVNHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRGSGINEDSKDIT
AYHTVFLTAILGGTIVIVIGFFAVLLCYCRDKCGTPQKRERNITKLEVLKRDQTTSTTHINHISTVKVALKAEDKSQLFNAKNSSYSPQK
KEPSKAETEERVSMVKTRDDFKIYNEDVSFLSVNQNNYSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPE
QLMHIYSQPIAILQTSDLFSTPEQLHTAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPIHSHAQPPDAREEDIILEGQQSLPSQASD
WSRYSSSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGV
DMNELHSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGSGVIMEHPGEESPGRKSTVEDFEANTSPTKRR

--------------------------------------------------------------
>40489_40489_3_ITGAV-FAM171B_ITGAV_chr2_187466878_ENST00000433736_FAM171B_chr2_187604955_ENST00000304698_length(transcript)=5686nt_BP=308nt
CTTTGTAGCTCCTGGAGATTCAATTCTTTCTTGCCAGGGTCTTTCTACCTCTGCCTCACATATTCCCTCCATCTCTTCATTCCACTTCCC
TCATCCCCACCCCCCACTCCCCTCCATCCTCAATACACAAATGCTCCTAGGCACCCTCCTTCTGATCCTGTACATCTTAATGTTGTGCCG
GATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTC
TACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGTGTCTGTATTTATGTTGAAAGTCCAGGTGAATGACATCATCAGTCGTCAGTA
CCTGAGCCAAGCAGTTGTAGAAGTGTTTGTAAACTACACGAAGACAAATTCCACAGTAACTAAAAGCAATGGAGCAGTGCTGATAAAAGT
ACCCTACAAATTAGGACTTAGTTTAACTATTATTGCTTACAAAGATGGCTACGTGTTGACCCCTCTGCCTTGGAAAACCAGAAGAATGCC
AATATATTCATCAGTTACACTTTCACTGTTCCCGCAAAGCCAAGCAAATATATGGCTATTTGAAGACACTGTTTTAATTACTGGAAAATT
AGCTGATGCCAAGTCTCAACCAAGTGTTCAGTTTTCAAAAGCCTTAATTAAACTTCCTGACAACCATCATATTAGCAACGTTACTGGCTA
TCTTACAGTTCTACAACAGTTTTTGAAAGTGGACAATTTTCTGCATACAACTGGAATTACTCTCAATAAACCAGGTTTTGAAAACATTGA
ATTGACTCCTCTTGCTGCAATATGTGTGAAAATATATTCTGGAGGAAAAGAACTAAAGGTCAATGGCTCTATTCAAGTTTCTCTTCCTCT
TCTACGTCTGAATGATATAAGTGCAGGGGATCGCATACCTGCTTGGACATTTGATATGAACACAGGTGCTTGGGTAAATCATGGTCGGGG
AATGGTCAAGGAACATAACAATCATTTAATCTGGACATATGATGCACCACATTTGGGGTACTGGATAGCAGCTCCACTTCCAGGAACTAG
AGGTTCAGGTATAAATGAAGATTCCAAGGACATAACTGCCTACCACACAGTGTTTCTTACAGCCATATTAGGAGGAACAATAGTCATTGT
CATTGGATTTTTTGCTGTACTACTTTGTTATTGCAGGGACAAGTGTGGTACTCCACAGAAAAGAGAAAGAAATATCACTAAACTTGAGGT
CCTCAAGAGAGACCAGACAACTTCAACAACACACATAAATCATATCAGTACAGTTAAAGTTGCATTAAAAGCTGAGGACAAGTCGCAGTT
ATTCAATGCCAAAAACTCCTCATATAGTCCTCAGAAAAAGGAACCATCAAAGGCAGAAACAGAAGAAAGAGTTTCCATGGTAAAAACTCG
GGACGATTTTAAAATCTACAATGAAGATGTTTCATTTCTATCAGTCAATCAAAATAATTACTCAAGAAACCCAACACAGTCTTTGGAGCC
CAATGTAGGGTCCAAACAACCTAAACATATTAACAACAATCTATCTTCATCTCTAGGTGATGCTCAAGATGAAAAGAGGTATCTCACAGG
TAATGAGGAGGCGTATGGGCGTTCCCATATTCCTGAACAGCTTATGCATATTTACAGCCAACCCATTGCCATCCTTCAAACATCTGACCT
TTTCTCCACACCGGAACAATTACATACTGCTAAGTCAGCTACTTTGCCAAGAAAGGGACAGTTAGTCTATGGCCAATTGATGGAACCAGT
AAATCGAGAGAACTTTACGCAGACCTTGCCCAAAATGCCAATTCATTCTCATGCACAGCCCCCAGATGCCAGGGAAGAGGATATCATACT
TGAAGGTCAACAGAGCCTGCCATCCCAGGCTTCAGATTGGAGCCGATACTCAAGCAGCTTACTGGAATCCGTCTCTGTTCCTGGAACACT
AAATGAGGCTGTTGTAATGACTCCATTTTCATCGGAACTTCAAGGAATTTCAGAACAGACCCTCCTGGAGCTGTCCAAAGGAAAGCCCTC
CCCGCATCCCAGAGCCTGGTTTGTGTCTCTTGATGGAAAGCCAGTTGCACAAGTGAGGCACTCCTTTATAGACCTGAAAAAGGGCAAGAG
AACCCAGAGCAATGACACCAGTCTGGACTCTGGGGTGGACATGAATGAGCTTCACTCAAGTAGAAAGCTCGAGAGGGAGAAAACATTCAT
CAAAAGCATGCATCAGCCCAAGATCCTTTACTTAGAAGATTTAGACCTAAGCAGCAGTGAGAGTGGAACCACCGTCTGTTCCCCTGAGGA
CCCAGCTTTAAGGCACATCCTAGATGGAGGGAGTGGAGTGATCATGGAGCACCCTGGAGAAGAGTCGCCAGGAAGGAAAAGCACTGTTGA
AGATTTTGAAGCTAATACATCCCCCACTAAAAGAAGGGGCAGACCACCACTAGCCAAAAGAGATAGCAAGACTAACATCTGGAAGAAGCG
AGAGGAACGCCCACTGATTCCCATAAATTAACTCCAATGGGGATTGTGTGTCTGCTGTCTCGTGCTGTTTATTCTTGCTTCTTGTTGTAA
ATTGCAGTACGAACTTAAGAAAATGAGACTGAGCAATCTCATGGTTCTTGGACATGTCTCAAGCAGAGTAAATGGTAATTCAGTAATCAG
AGAGAAAGATACCAAGGAATGCTTTTTCTGGCCTATTCATTTATTTTTGGGTGATGAATTTACAGTATCTAAGTTTTCAAAATGTAAAAT
AGCTTCAAGATGTTAGTTATCTGAAAATGTTGCTCAGCCAGCCAGTTTGGCCTTGACTCTCTTAAGAATAACAGTGAAATATATACTCCT
CAAGTTGCCTCCAAAAATGTTGCCTCTACCATGGTGACTACCCCATGGAACATTTAGAAACAAAACTGACTTCAGGCATCATATTATTTT
AAATGTTACTATTACGTCTTCTTCTGCCTATACTTAAAAATAACTTGATAAATGACTTGGACTGATGTTACTCTGGAGTTATCACAAAGA
AAATGTTGTTTGGTCTTTAAAGAGCATGTGTATTGTATCATCCCAAACGTAAATCCTACATTTATATAAGATGGGCAAGAAGCTACTTGG
TCATTAGAGAGGGAGACACCAGCTCTTTGGTTGTTTTTGGATATAACTTTACAAAATAAGTAAGATGTTAATTTAGAAATTTGAGAAATT
AATGCTCTAATACTGAGTTTTTATTTAAAAATTATTTTTTCTTCCCCTCAACAATGAAGCAAGCTTAGCTGTCAAGGGAAACTTTTTACA
AATCTGAAAAAAACAATCTATGACTTTGGTTTAAGGCTCACTGATACTTTTAGGCTAAATTGGTTTTAATATATTTCTTCTATTCTAAAA
ACCTGAACTCAGTCACTTAAAGGCTATGAAATTTAAAAAAAAAGTCGATGTGAAAGTTTCTTTTGAACACTAAAATAAAATATGTGCAGA
TAAAATATACATTGATTTGTTTTTCTTAAATGTTGATGAGAAGAAAAAGAGATGCCATTTTCCTGAGGCTCAAAAATACCTTCAGGATAG
TTGTATATCCAGTTATTGATTTTCTTAAAAGATGTGTAAGGAAAACAGTTTCAATTTCAGGGGAAAAGTAAAAGTTTTTCCCTAAGTCAC
TTAAAGCCTTTGCAACTTCTTTTTTCAGTTTTGTAAGTAATATATCTATGTTCTTTTCATTATAGCAAGCATTCAATGTGAACAACTTTT
TAATTAACTCTGAATTACCATTCATACATCCTAAAAATAAAAGCTCGTTATTCATTAAAATCAACTGATCCCATTTTTCTTAAAATTTCC
CTGAAGGCAAATGTCTGAAGCACCTTTCCCTTGTGGGGGTAAAAATCCTAAATTGCTTTATTTTTCATTCCCTCCTATTCAACATGGGAG
CAGCATAGAGACCCAAACCATGTAAACAAGTTCAGTGAACCAAAACAGCCACATTAGCTTCAGTAAAATTATAGCTAGATGTGCAATTTT
TTCCTCCAACTTCTAACGTGTCAAATAACCTTCCTACTGTTCTGTGTTAACTGAAAGAACATAAAGACCCTAGGCAAATATTTGCTATAT
ATTACCCCAATCCATAGAAGAAATAATGTTTTGGGTAATACCTAGGCTTCCTTTTTTTTTTTTTTTTTTTTTTTTTAGTGATAAGGCTCA
TAACAATTAATTAGAGAAGGCTTCTTATTGGTCTTACACAGAAAGATACATCAAAAGCAGCATGACTCAAAATGATTTGGAAAAGGTTAA
AGTTAGTGCTCTGCTGAAGTGCCTTTGATATAGACTTGCATTATTAGAAGGATATAACATCTTTTTTAAGTGTGCATTTTCTTTCAGTTA
ACCAAATTAAACAGATGTGCAGTTTTATTAAAAATATAGACCTAGTGTTTCATGTTGGAACAATAAATATTGCATGTGAGTAGTATTTCT
TGTTTTTTGAATACAGTATATATTGATAAATTGTTTATGTTGGAATGAAGTTAGAAACTATATAGCAAAACATTATATTTTAAGTGTTTA
TTTTTCCCACCTTTAAATAAAAATGTTTCATCTCAGCTTGGTAATGAAATACACATATTGGTATAAGGGTATACCATTCAGGTATGCCAC
TTATTTTATTCATTTTTGTGTAAGGGAAATGAGATGATGTATCCCAAGGGCTTTTCTAGAACTACTTGTTTGCTTTCAGAATAAAACCTT
ATTATTTTTTACACTGCACATGCTGTTCTCAATTGGTAATTATAGGCAATTTATCTTTTCTAATGATCAAAAGAGTGTGACTTCTCATTT
GTGAGTAGTTCACAAATTTCCTGTTAAAAAGCTGAAACCATCTACTTTTTCTTAACCCAAGTGATAATAAACAATATTCACAACTTTCTT
AAATTTTTAAATTGAAAACCAAGGTTTTTTCAAATATAAACCTAGATGATTTTGGTCACAAATTGTTAACATTTGTCGATCCTTTGTATA
TACTTTGGATATATATTAAAGGCAAAACTATCTCTTGACTAACTGATGGATTCATTTACTAAAGCACAGCTGTATGTATTTTTGAATACA
TATTATGATCTTGAGACTTTATAAATCAATTTTTATGACTTTATGCAGTTGTATAGGGATTATGCCCTTTCAGTTCTATAGGGATTATGC
CCTTTTATAATACATAATATACCACAGAGATTACAAATGTTGAGGAATGAAAGCACTTCTTTGCTTTGGCAATCATTTTCAGACCACTAT
GTGTTTGAATCCTCTGGTATCAATACGTATTATAGGGTTTTAGAGATCTGTGGGTCAAATGATGTCCCTCAAAACTTCCTAAAAAGGTGA
AGCTCAAAGTCACACATTCTTATAAGGCGCATGAGTTTCTCATTTTCCCATGTACGAGCATTGTAAAGGAATTCAGCTGTATTAATTTCT
ATTTCAGATCTAGAATTGACATTTTGCCTTCTTGTTTCCAGGTGTTTCTATTTTTTGTATTCTTTCAGAGAAATCTCATATTTCGGTGTA
TTTATTGCTGTTACTACTATATTTACTGCTGAAAACTGTAACAACCTGAAGATTTGTAAAATGTTAAACATAGTTCATTAAAAATAATAA

>40489_40489_3_ITGAV-FAM171B_ITGAV_chr2_187466878_ENST00000433736_FAM171B_chr2_187604955_ENST00000304698_length(amino acids)=806AA_BP=0
MLLGTLLLILYILMLCRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATVSVFMLKVQVNDIISRQYLSQAVVEVFVNYT
KTNSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSK
ALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFENIELTPLAAICVKIYSGGKELKVNGSIQVSLPLLRLNDISAGDRIP
AWTFDMNTGAWVNHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRGSGINEDSKDITAYHTVFLTAILGGTIVIVIGFFAVLLCYCRD
KCGTPQKRERNITKLEVLKRDQTTSTTHINHISTVKVALKAEDKSQLFNAKNSSYSPQKKEPSKAETEERVSMVKTRDDFKIYNEDVSFL
SVNQNNYSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPEQLMHIYSQPIAILQTSDLFSTPEQLHTAKSA
TLPRKGQLVYGQLMEPVNRENFTQTLPKMPIHSHAQPPDAREEDIILEGQQSLPSQASDWSRYSSSLLESVSVPGTLNEAVVMTPFSSEL
QGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNELHSSRKLEREKTFIKSMHQPKILYLED

--------------------------------------------------------------
>40489_40489_4_ITGAV-FAM171B_ITGAV_chr2_187498101_ENST00000261023_FAM171B_chr2_187604955_ENST00000304698_length(transcript)=6283nt_BP=905nt
CCTCAGACGCTGCGTGGAGCGGCGGAGCCGGAGGGAAGCAAAGGACCGTCTGCGCTGCTGTCCCCGCCCCGCGCGCTCTGCGCCCCTCGT
CCCTGGCGGTCGCTCCGAAGCTCAGCCCTCTTGCCTGCCCCGGAGCTGTCCCGGGCTAGCCGAGAAGAGAGCGGCCGGCAAGTTTGGGCG
CGCGCAGGCGGCGGGCCGCGGGCACTGGGCGCCTCGCTGGGGCGGGGGGAGGTGGCTACCGCTCCCGGCTTGGCGTCCCGCGCGCACTTC
GGCGATGGCTTTTCCGCCGCGGCGACGGCTGCGCCTCGGTCCCCGCGGCCTCCCGCTTCTTCTCTCGGGACTCCTGCTACCTCTGTGCCG
CGCCTTCAACCTAGACGTGGACAGTCCTGCCGAGTACTCTGGCCCCGAGGGAAGTTACTTCGGCTTCGCCGTGGATTTCTTCGTGCCCAG
CGCGTCTTCCCGGATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATG
TGACTGGTCTTCTACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAA
GTCCCATCAGTGGTTTGGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAA
ACAGGAGCGAGAGCCTGTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACAAGATATTGATGC
TGATGGACAGGGATTTTGTCAAGGAGGATTCAGCATTGATTTTACTAAAGCTGACAGAGTACTTCTTGGTGGTCCTGGTAGCTTTTATTG
GCAAGTGTCTGTATTTATGTTGAAAGTCCAGGTGAATGACATCATCAGTCGTCAGTACCTGAGCCAAGCAGTTGTAGAAGTGTTTGTAAA
CTACACGAAGACAAATTCCACAGTAACTAAAAGCAATGGAGCAGTGCTGATAAAAGTACCCTACAAATTAGGACTTAGTTTAACTATTAT
TGCTTACAAAGATGGCTACGTGTTGACCCCTCTGCCTTGGAAAACCAGAAGAATGCCAATATATTCATCAGTTACACTTTCACTGTTCCC
GCAAAGCCAAGCAAATATATGGCTATTTGAAGACACTGTTTTAATTACTGGAAAATTAGCTGATGCCAAGTCTCAACCAAGTGTTCAGTT
TTCAAAAGCCTTAATTAAACTTCCTGACAACCATCATATTAGCAACGTTACTGGCTATCTTACAGTTCTACAACAGTTTTTGAAAGTGGA
CAATTTTCTGCATACAACTGGAATTACTCTCAATAAACCAGGTTTTGAAAACATTGAATTGACTCCTCTTGCTGCAATATGTGTGAAAAT
ATATTCTGGAGGAAAAGAACTAAAGGTCAATGGCTCTATTCAAGTTTCTCTTCCTCTTCTACGTCTGAATGATATAAGTGCAGGGGATCG
CATACCTGCTTGGACATTTGATATGAACACAGGTGCTTGGGTAAATCATGGTCGGGGAATGGTCAAGGAACATAACAATCATTTAATCTG
GACATATGATGCACCACATTTGGGGTACTGGATAGCAGCTCCACTTCCAGGAACTAGAGGTTCAGGTATAAATGAAGATTCCAAGGACAT
AACTGCCTACCACACAGTGTTTCTTACAGCCATATTAGGAGGAACAATAGTCATTGTCATTGGATTTTTTGCTGTACTACTTTGTTATTG
CAGGGACAAGTGTGGTACTCCACAGAAAAGAGAAAGAAATATCACTAAACTTGAGGTCCTCAAGAGAGACCAGACAACTTCAACAACACA
CATAAATCATATCAGTACAGTTAAAGTTGCATTAAAAGCTGAGGACAAGTCGCAGTTATTCAATGCCAAAAACTCCTCATATAGTCCTCA
GAAAAAGGAACCATCAAAGGCAGAAACAGAAGAAAGAGTTTCCATGGTAAAAACTCGGGACGATTTTAAAATCTACAATGAAGATGTTTC
ATTTCTATCAGTCAATCAAAATAATTACTCAAGAAACCCAACACAGTCTTTGGAGCCCAATGTAGGGTCCAAACAACCTAAACATATTAA
CAACAATCTATCTTCATCTCTAGGTGATGCTCAAGATGAAAAGAGGTATCTCACAGGTAATGAGGAGGCGTATGGGCGTTCCCATATTCC
TGAACAGCTTATGCATATTTACAGCCAACCCATTGCCATCCTTCAAACATCTGACCTTTTCTCCACACCGGAACAATTACATACTGCTAA
GTCAGCTACTTTGCCAAGAAAGGGACAGTTAGTCTATGGCCAATTGATGGAACCAGTAAATCGAGAGAACTTTACGCAGACCTTGCCCAA
AATGCCAATTCATTCTCATGCACAGCCCCCAGATGCCAGGGAAGAGGATATCATACTTGAAGGTCAACAGAGCCTGCCATCCCAGGCTTC
AGATTGGAGCCGATACTCAAGCAGCTTACTGGAATCCGTCTCTGTTCCTGGAACACTAAATGAGGCTGTTGTAATGACTCCATTTTCATC
GGAACTTCAAGGAATTTCAGAACAGACCCTCCTGGAGCTGTCCAAAGGAAAGCCCTCCCCGCATCCCAGAGCCTGGTTTGTGTCTCTTGA
TGGAAAGCCAGTTGCACAAGTGAGGCACTCCTTTATAGACCTGAAAAAGGGCAAGAGAACCCAGAGCAATGACACCAGTCTGGACTCTGG
GGTGGACATGAATGAGCTTCACTCAAGTAGAAAGCTCGAGAGGGAGAAAACATTCATCAAAAGCATGCATCAGCCCAAGATCCTTTACTT
AGAAGATTTAGACCTAAGCAGCAGTGAGAGTGGAACCACCGTCTGTTCCCCTGAGGACCCAGCTTTAAGGCACATCCTAGATGGAGGGAG
TGGAGTGATCATGGAGCACCCTGGAGAAGAGTCGCCAGGAAGGAAAAGCACTGTTGAAGATTTTGAAGCTAATACATCCCCCACTAAAAG
AAGGGGCAGACCACCACTAGCCAAAAGAGATAGCAAGACTAACATCTGGAAGAAGCGAGAGGAACGCCCACTGATTCCCATAAATTAACT
CCAATGGGGATTGTGTGTCTGCTGTCTCGTGCTGTTTATTCTTGCTTCTTGTTGTAAATTGCAGTACGAACTTAAGAAAATGAGACTGAG
CAATCTCATGGTTCTTGGACATGTCTCAAGCAGAGTAAATGGTAATTCAGTAATCAGAGAGAAAGATACCAAGGAATGCTTTTTCTGGCC
TATTCATTTATTTTTGGGTGATGAATTTACAGTATCTAAGTTTTCAAAATGTAAAATAGCTTCAAGATGTTAGTTATCTGAAAATGTTGC
TCAGCCAGCCAGTTTGGCCTTGACTCTCTTAAGAATAACAGTGAAATATATACTCCTCAAGTTGCCTCCAAAAATGTTGCCTCTACCATG
GTGACTACCCCATGGAACATTTAGAAACAAAACTGACTTCAGGCATCATATTATTTTAAATGTTACTATTACGTCTTCTTCTGCCTATAC
TTAAAAATAACTTGATAAATGACTTGGACTGATGTTACTCTGGAGTTATCACAAAGAAAATGTTGTTTGGTCTTTAAAGAGCATGTGTAT
TGTATCATCCCAAACGTAAATCCTACATTTATATAAGATGGGCAAGAAGCTACTTGGTCATTAGAGAGGGAGACACCAGCTCTTTGGTTG
TTTTTGGATATAACTTTACAAAATAAGTAAGATGTTAATTTAGAAATTTGAGAAATTAATGCTCTAATACTGAGTTTTTATTTAAAAATT
ATTTTTTCTTCCCCTCAACAATGAAGCAAGCTTAGCTGTCAAGGGAAACTTTTTACAAATCTGAAAAAAACAATCTATGACTTTGGTTTA
AGGCTCACTGATACTTTTAGGCTAAATTGGTTTTAATATATTTCTTCTATTCTAAAAACCTGAACTCAGTCACTTAAAGGCTATGAAATT
TAAAAAAAAAGTCGATGTGAAAGTTTCTTTTGAACACTAAAATAAAATATGTGCAGATAAAATATACATTGATTTGTTTTTCTTAAATGT
TGATGAGAAGAAAAAGAGATGCCATTTTCCTGAGGCTCAAAAATACCTTCAGGATAGTTGTATATCCAGTTATTGATTTTCTTAAAAGAT
GTGTAAGGAAAACAGTTTCAATTTCAGGGGAAAAGTAAAAGTTTTTCCCTAAGTCACTTAAAGCCTTTGCAACTTCTTTTTTCAGTTTTG
TAAGTAATATATCTATGTTCTTTTCATTATAGCAAGCATTCAATGTGAACAACTTTTTAATTAACTCTGAATTACCATTCATACATCCTA
AAAATAAAAGCTCGTTATTCATTAAAATCAACTGATCCCATTTTTCTTAAAATTTCCCTGAAGGCAAATGTCTGAAGCACCTTTCCCTTG
TGGGGGTAAAAATCCTAAATTGCTTTATTTTTCATTCCCTCCTATTCAACATGGGAGCAGCATAGAGACCCAAACCATGTAAACAAGTTC
AGTGAACCAAAACAGCCACATTAGCTTCAGTAAAATTATAGCTAGATGTGCAATTTTTTCCTCCAACTTCTAACGTGTCAAATAACCTTC
CTACTGTTCTGTGTTAACTGAAAGAACATAAAGACCCTAGGCAAATATTTGCTATATATTACCCCAATCCATAGAAGAAATAATGTTTTG
GGTAATACCTAGGCTTCCTTTTTTTTTTTTTTTTTTTTTTTTTAGTGATAAGGCTCATAACAATTAATTAGAGAAGGCTTCTTATTGGTC
TTACACAGAAAGATACATCAAAAGCAGCATGACTCAAAATGATTTGGAAAAGGTTAAAGTTAGTGCTCTGCTGAAGTGCCTTTGATATAG
ACTTGCATTATTAGAAGGATATAACATCTTTTTTAAGTGTGCATTTTCTTTCAGTTAACCAAATTAAACAGATGTGCAGTTTTATTAAAA
ATATAGACCTAGTGTTTCATGTTGGAACAATAAATATTGCATGTGAGTAGTATTTCTTGTTTTTTGAATACAGTATATATTGATAAATTG
TTTATGTTGGAATGAAGTTAGAAACTATATAGCAAAACATTATATTTTAAGTGTTTATTTTTCCCACCTTTAAATAAAAATGTTTCATCT
CAGCTTGGTAATGAAATACACATATTGGTATAAGGGTATACCATTCAGGTATGCCACTTATTTTATTCATTTTTGTGTAAGGGAAATGAG
ATGATGTATCCCAAGGGCTTTTCTAGAACTACTTGTTTGCTTTCAGAATAAAACCTTATTATTTTTTACACTGCACATGCTGTTCTCAAT
TGGTAATTATAGGCAATTTATCTTTTCTAATGATCAAAAGAGTGTGACTTCTCATTTGTGAGTAGTTCACAAATTTCCTGTTAAAAAGCT
GAAACCATCTACTTTTTCTTAACCCAAGTGATAATAAACAATATTCACAACTTTCTTAAATTTTTAAATTGAAAACCAAGGTTTTTTCAA
ATATAAACCTAGATGATTTTGGTCACAAATTGTTAACATTTGTCGATCCTTTGTATATACTTTGGATATATATTAAAGGCAAAACTATCT
CTTGACTAACTGATGGATTCATTTACTAAAGCACAGCTGTATGTATTTTTGAATACATATTATGATCTTGAGACTTTATAAATCAATTTT
TATGACTTTATGCAGTTGTATAGGGATTATGCCCTTTCAGTTCTATAGGGATTATGCCCTTTTATAATACATAATATACCACAGAGATTA
CAAATGTTGAGGAATGAAAGCACTTCTTTGCTTTGGCAATCATTTTCAGACCACTATGTGTTTGAATCCTCTGGTATCAATACGTATTAT
AGGGTTTTAGAGATCTGTGGGTCAAATGATGTCCCTCAAAACTTCCTAAAAAGGTGAAGCTCAAAGTCACACATTCTTATAAGGCGCATG
AGTTTCTCATTTTCCCATGTACGAGCATTGTAAAGGAATTCAGCTGTATTAATTTCTATTTCAGATCTAGAATTGACATTTTGCCTTCTT
GTTTCCAGGTGTTTCTATTTTTTGTATTCTTTCAGAGAAATCTCATATTTCGGTGTATTTATTGCTGTTACTACTATATTTACTGCTGAA

>40489_40489_4_ITGAV-FAM171B_ITGAV_chr2_187498101_ENST00000261023_FAM171B_chr2_187604955_ENST00000304698_length(amino acids)=1032AA_BP=1
MRCCPRPARSAPLVPGGRSEAQPSCLPRSCPGLAEKRAAGKFGRAQAAGRGHWAPRWGGGRWLPLPAWRPARTSAMAFPPRRRLRLGPRG
LPLLLSGLLLPLCRAFNLDVDSPAEYSGPEGSYFGFAVDFFVPSASSRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDAT
GNRDYAKDDPLEFKSHQWFGASVRSKQDKILACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTK
ADRVLLGGPGSFYWQVSVFMLKVQVNDIISRQYLSQAVVEVFVNYTKTNSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTR
RMPIYSSVTLSLFPQSQANIWLFEDTVLITGKLADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFE
NIELTPLAAICVKIYSGGKELKVNGSIQVSLPLLRLNDISAGDRIPAWTFDMNTGAWVNHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLP
GTRGSGINEDSKDITAYHTVFLTAILGGTIVIVIGFFAVLLCYCRDKCGTPQKRERNITKLEVLKRDQTTSTTHINHISTVKVALKAEDK
SQLFNAKNSSYSPQKKEPSKAETEERVSMVKTRDDFKIYNEDVSFLSVNQNNYSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRY
LTGNEEAYGRSHIPEQLMHIYSQPIAILQTSDLFSTPEQLHTAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPIHSHAQPPDAREED
IILEGQQSLPSQASDWSRYSSSLLESVSVPGTLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKK
GKRTQSNDTSLDSGVDMNELHSSRKLEREKTFIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGSGVIMEHPGEESPGRKS

--------------------------------------------------------------
>40489_40489_5_ITGAV-FAM171B_ITGAV_chr2_187498101_ENST00000433736_FAM171B_chr2_187604955_ENST00000304698_length(transcript)=6001nt_BP=623nt
CTTTGTAGCTCCTGGAGATTCAATTCTTTCTTGCCAGGGTCTTTCTACCTCTGCCTCACATATTCCCTCCATCTCTTCATTCCACTTCCC
TCATCCCCACCCCCCACTCCCCTCCATCCTCAATACACAAATGCTCCTAGGCACCCTCCTTCTGATCCTGTACATCTTAATGTTGTGCCG
GATGTTTCTTCTCGTGGGAGCTCCCAAAGCAAACACCACCCAGCCTGGGATTGTGGAAGGAGGGCAGGTCCTCAAATGTGACTGGTCTTC
TACCCGCCGGTGCCAGCCAATTGAATTTGATGCAACAGGCAATAGAGATTATGCCAAGGATGATCCATTGGAATTTAAGTCCCATCAGTG
GTTTGGAGCATCTGTGAGGTCGAAACAGGATAAAATTTTGGCCTGTGCCCCATTGTACCATTGGAGAACTGAGATGAAACAGGAGCGAGA
GCCTGTTGGAACATGCTTTCTTCAAGATGGAACAAAGACTGTTGAGTATGCTCCATGTAGATCACAAGATATTGATGCTGATGGACAGGG
ATTTTGTCAAGGAGGATTCAGCATTGATTTTACTAAAGCTGACAGAGTACTTCTTGGTGGTCCTGGTAGCTTTTATTGGCAAGTGTCTGT
ATTTATGTTGAAAGTCCAGGTGAATGACATCATCAGTCGTCAGTACCTGAGCCAAGCAGTTGTAGAAGTGTTTGTAAACTACACGAAGAC
AAATTCCACAGTAACTAAAAGCAATGGAGCAGTGCTGATAAAAGTACCCTACAAATTAGGACTTAGTTTAACTATTATTGCTTACAAAGA
TGGCTACGTGTTGACCCCTCTGCCTTGGAAAACCAGAAGAATGCCAATATATTCATCAGTTACACTTTCACTGTTCCCGCAAAGCCAAGC
AAATATATGGCTATTTGAAGACACTGTTTTAATTACTGGAAAATTAGCTGATGCCAAGTCTCAACCAAGTGTTCAGTTTTCAAAAGCCTT
AATTAAACTTCCTGACAACCATCATATTAGCAACGTTACTGGCTATCTTACAGTTCTACAACAGTTTTTGAAAGTGGACAATTTTCTGCA
TACAACTGGAATTACTCTCAATAAACCAGGTTTTGAAAACATTGAATTGACTCCTCTTGCTGCAATATGTGTGAAAATATATTCTGGAGG
AAAAGAACTAAAGGTCAATGGCTCTATTCAAGTTTCTCTTCCTCTTCTACGTCTGAATGATATAAGTGCAGGGGATCGCATACCTGCTTG
GACATTTGATATGAACACAGGTGCTTGGGTAAATCATGGTCGGGGAATGGTCAAGGAACATAACAATCATTTAATCTGGACATATGATGC
ACCACATTTGGGGTACTGGATAGCAGCTCCACTTCCAGGAACTAGAGGTTCAGGTATAAATGAAGATTCCAAGGACATAACTGCCTACCA
CACAGTGTTTCTTACAGCCATATTAGGAGGAACAATAGTCATTGTCATTGGATTTTTTGCTGTACTACTTTGTTATTGCAGGGACAAGTG
TGGTACTCCACAGAAAAGAGAAAGAAATATCACTAAACTTGAGGTCCTCAAGAGAGACCAGACAACTTCAACAACACACATAAATCATAT
CAGTACAGTTAAAGTTGCATTAAAAGCTGAGGACAAGTCGCAGTTATTCAATGCCAAAAACTCCTCATATAGTCCTCAGAAAAAGGAACC
ATCAAAGGCAGAAACAGAAGAAAGAGTTTCCATGGTAAAAACTCGGGACGATTTTAAAATCTACAATGAAGATGTTTCATTTCTATCAGT
CAATCAAAATAATTACTCAAGAAACCCAACACAGTCTTTGGAGCCCAATGTAGGGTCCAAACAACCTAAACATATTAACAACAATCTATC
TTCATCTCTAGGTGATGCTCAAGATGAAAAGAGGTATCTCACAGGTAATGAGGAGGCGTATGGGCGTTCCCATATTCCTGAACAGCTTAT
GCATATTTACAGCCAACCCATTGCCATCCTTCAAACATCTGACCTTTTCTCCACACCGGAACAATTACATACTGCTAAGTCAGCTACTTT
GCCAAGAAAGGGACAGTTAGTCTATGGCCAATTGATGGAACCAGTAAATCGAGAGAACTTTACGCAGACCTTGCCCAAAATGCCAATTCA
TTCTCATGCACAGCCCCCAGATGCCAGGGAAGAGGATATCATACTTGAAGGTCAACAGAGCCTGCCATCCCAGGCTTCAGATTGGAGCCG
ATACTCAAGCAGCTTACTGGAATCCGTCTCTGTTCCTGGAACACTAAATGAGGCTGTTGTAATGACTCCATTTTCATCGGAACTTCAAGG
AATTTCAGAACAGACCCTCCTGGAGCTGTCCAAAGGAAAGCCCTCCCCGCATCCCAGAGCCTGGTTTGTGTCTCTTGATGGAAAGCCAGT
TGCACAAGTGAGGCACTCCTTTATAGACCTGAAAAAGGGCAAGAGAACCCAGAGCAATGACACCAGTCTGGACTCTGGGGTGGACATGAA
TGAGCTTCACTCAAGTAGAAAGCTCGAGAGGGAGAAAACATTCATCAAAAGCATGCATCAGCCCAAGATCCTTTACTTAGAAGATTTAGA
CCTAAGCAGCAGTGAGAGTGGAACCACCGTCTGTTCCCCTGAGGACCCAGCTTTAAGGCACATCCTAGATGGAGGGAGTGGAGTGATCAT
GGAGCACCCTGGAGAAGAGTCGCCAGGAAGGAAAAGCACTGTTGAAGATTTTGAAGCTAATACATCCCCCACTAAAAGAAGGGGCAGACC
ACCACTAGCCAAAAGAGATAGCAAGACTAACATCTGGAAGAAGCGAGAGGAACGCCCACTGATTCCCATAAATTAACTCCAATGGGGATT
GTGTGTCTGCTGTCTCGTGCTGTTTATTCTTGCTTCTTGTTGTAAATTGCAGTACGAACTTAAGAAAATGAGACTGAGCAATCTCATGGT
TCTTGGACATGTCTCAAGCAGAGTAAATGGTAATTCAGTAATCAGAGAGAAAGATACCAAGGAATGCTTTTTCTGGCCTATTCATTTATT
TTTGGGTGATGAATTTACAGTATCTAAGTTTTCAAAATGTAAAATAGCTTCAAGATGTTAGTTATCTGAAAATGTTGCTCAGCCAGCCAG
TTTGGCCTTGACTCTCTTAAGAATAACAGTGAAATATATACTCCTCAAGTTGCCTCCAAAAATGTTGCCTCTACCATGGTGACTACCCCA
TGGAACATTTAGAAACAAAACTGACTTCAGGCATCATATTATTTTAAATGTTACTATTACGTCTTCTTCTGCCTATACTTAAAAATAACT
TGATAAATGACTTGGACTGATGTTACTCTGGAGTTATCACAAAGAAAATGTTGTTTGGTCTTTAAAGAGCATGTGTATTGTATCATCCCA
AACGTAAATCCTACATTTATATAAGATGGGCAAGAAGCTACTTGGTCATTAGAGAGGGAGACACCAGCTCTTTGGTTGTTTTTGGATATA
ACTTTACAAAATAAGTAAGATGTTAATTTAGAAATTTGAGAAATTAATGCTCTAATACTGAGTTTTTATTTAAAAATTATTTTTTCTTCC
CCTCAACAATGAAGCAAGCTTAGCTGTCAAGGGAAACTTTTTACAAATCTGAAAAAAACAATCTATGACTTTGGTTTAAGGCTCACTGAT
ACTTTTAGGCTAAATTGGTTTTAATATATTTCTTCTATTCTAAAAACCTGAACTCAGTCACTTAAAGGCTATGAAATTTAAAAAAAAAGT
CGATGTGAAAGTTTCTTTTGAACACTAAAATAAAATATGTGCAGATAAAATATACATTGATTTGTTTTTCTTAAATGTTGATGAGAAGAA
AAAGAGATGCCATTTTCCTGAGGCTCAAAAATACCTTCAGGATAGTTGTATATCCAGTTATTGATTTTCTTAAAAGATGTGTAAGGAAAA
CAGTTTCAATTTCAGGGGAAAAGTAAAAGTTTTTCCCTAAGTCACTTAAAGCCTTTGCAACTTCTTTTTTCAGTTTTGTAAGTAATATAT
CTATGTTCTTTTCATTATAGCAAGCATTCAATGTGAACAACTTTTTAATTAACTCTGAATTACCATTCATACATCCTAAAAATAAAAGCT
CGTTATTCATTAAAATCAACTGATCCCATTTTTCTTAAAATTTCCCTGAAGGCAAATGTCTGAAGCACCTTTCCCTTGTGGGGGTAAAAA
TCCTAAATTGCTTTATTTTTCATTCCCTCCTATTCAACATGGGAGCAGCATAGAGACCCAAACCATGTAAACAAGTTCAGTGAACCAAAA
CAGCCACATTAGCTTCAGTAAAATTATAGCTAGATGTGCAATTTTTTCCTCCAACTTCTAACGTGTCAAATAACCTTCCTACTGTTCTGT
GTTAACTGAAAGAACATAAAGACCCTAGGCAAATATTTGCTATATATTACCCCAATCCATAGAAGAAATAATGTTTTGGGTAATACCTAG
GCTTCCTTTTTTTTTTTTTTTTTTTTTTTTTAGTGATAAGGCTCATAACAATTAATTAGAGAAGGCTTCTTATTGGTCTTACACAGAAAG
ATACATCAAAAGCAGCATGACTCAAAATGATTTGGAAAAGGTTAAAGTTAGTGCTCTGCTGAAGTGCCTTTGATATAGACTTGCATTATT
AGAAGGATATAACATCTTTTTTAAGTGTGCATTTTCTTTCAGTTAACCAAATTAAACAGATGTGCAGTTTTATTAAAAATATAGACCTAG
TGTTTCATGTTGGAACAATAAATATTGCATGTGAGTAGTATTTCTTGTTTTTTGAATACAGTATATATTGATAAATTGTTTATGTTGGAA
TGAAGTTAGAAACTATATAGCAAAACATTATATTTTAAGTGTTTATTTTTCCCACCTTTAAATAAAAATGTTTCATCTCAGCTTGGTAAT
GAAATACACATATTGGTATAAGGGTATACCATTCAGGTATGCCACTTATTTTATTCATTTTTGTGTAAGGGAAATGAGATGATGTATCCC
AAGGGCTTTTCTAGAACTACTTGTTTGCTTTCAGAATAAAACCTTATTATTTTTTACACTGCACATGCTGTTCTCAATTGGTAATTATAG
GCAATTTATCTTTTCTAATGATCAAAAGAGTGTGACTTCTCATTTGTGAGTAGTTCACAAATTTCCTGTTAAAAAGCTGAAACCATCTAC
TTTTTCTTAACCCAAGTGATAATAAACAATATTCACAACTTTCTTAAATTTTTAAATTGAAAACCAAGGTTTTTTCAAATATAAACCTAG
ATGATTTTGGTCACAAATTGTTAACATTTGTCGATCCTTTGTATATACTTTGGATATATATTAAAGGCAAAACTATCTCTTGACTAACTG
ATGGATTCATTTACTAAAGCACAGCTGTATGTATTTTTGAATACATATTATGATCTTGAGACTTTATAAATCAATTTTTATGACTTTATG
CAGTTGTATAGGGATTATGCCCTTTCAGTTCTATAGGGATTATGCCCTTTTATAATACATAATATACCACAGAGATTACAAATGTTGAGG
AATGAAAGCACTTCTTTGCTTTGGCAATCATTTTCAGACCACTATGTGTTTGAATCCTCTGGTATCAATACGTATTATAGGGTTTTAGAG
ATCTGTGGGTCAAATGATGTCCCTCAAAACTTCCTAAAAAGGTGAAGCTCAAAGTCACACATTCTTATAAGGCGCATGAGTTTCTCATTT
TCCCATGTACGAGCATTGTAAAGGAATTCAGCTGTATTAATTTCTATTTCAGATCTAGAATTGACATTTTGCCTTCTTGTTTCCAGGTGT
TTCTATTTTTTGTATTCTTTCAGAGAAATCTCATATTTCGGTGTATTTATTGCTGTTACTACTATATTTACTGCTGAAAACTGTAACAAC

>40489_40489_5_ITGAV-FAM171B_ITGAV_chr2_187498101_ENST00000433736_FAM171B_chr2_187604955_ENST00000304698_length(amino acids)=911AA_BP=0
MLLGTLLLILYILMLCRMFLLVGAPKANTTQPGIVEGGQVLKCDWSSTRRCQPIEFDATGNRDYAKDDPLEFKSHQWFGASVRSKQDKIL
ACAPLYHWRTEMKQEREPVGTCFLQDGTKTVEYAPCRSQDIDADGQGFCQGGFSIDFTKADRVLLGGPGSFYWQVSVFMLKVQVNDIISR
QYLSQAVVEVFVNYTKTNSTVTKSNGAVLIKVPYKLGLSLTIIAYKDGYVLTPLPWKTRRMPIYSSVTLSLFPQSQANIWLFEDTVLITG
KLADAKSQPSVQFSKALIKLPDNHHISNVTGYLTVLQQFLKVDNFLHTTGITLNKPGFENIELTPLAAICVKIYSGGKELKVNGSIQVSL
PLLRLNDISAGDRIPAWTFDMNTGAWVNHGRGMVKEHNNHLIWTYDAPHLGYWIAAPLPGTRGSGINEDSKDITAYHTVFLTAILGGTIV
IVIGFFAVLLCYCRDKCGTPQKRERNITKLEVLKRDQTTSTTHINHISTVKVALKAEDKSQLFNAKNSSYSPQKKEPSKAETEERVSMVK
TRDDFKIYNEDVSFLSVNQNNYSRNPTQSLEPNVGSKQPKHINNNLSSSLGDAQDEKRYLTGNEEAYGRSHIPEQLMHIYSQPIAILQTS
DLFSTPEQLHTAKSATLPRKGQLVYGQLMEPVNRENFTQTLPKMPIHSHAQPPDAREEDIILEGQQSLPSQASDWSRYSSSLLESVSVPG
TLNEAVVMTPFSSELQGISEQTLLELSKGKPSPHPRAWFVSLDGKPVAQVRHSFIDLKKGKRTQSNDTSLDSGVDMNELHSSRKLEREKT
FIKSMHQPKILYLEDLDLSSSESGTTVCSPEDPALRHILDGGSGVIMEHPGEESPGRKSTVEDFEANTSPTKRRGRPPLAKRDSKTNIWK

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Fusion Gene PPI Analysis for ITGAV-FAM171B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ITGAV-FAM171B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ITGAV-FAM171B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource