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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:IWS1-CCNY (FusionGDB2 ID:40796)

Fusion Gene Summary for IWS1-CCNY

check button Fusion gene summary
Fusion gene informationFusion gene name: IWS1-CCNY
Fusion gene ID: 40796
HgeneTgene
Gene symbol

IWS1

CCNY

Gene ID

55677

219771

Gene nameinteracts with SUPT6H, CTD assembly factor 1cyclin Y
Synonyms-C10orf9|CBCP1|CCNX|CFP1
Cytomap

2q14.3

10p11.21

Type of geneprotein-codingprotein-coding
Descriptionprotein IWS1 homologIWS1 homologIWS1, SUPT6H interacting proteinIWS1-like proteininteracts with Spt6cyclin-Ycyc-Ycyclin box protein 1cyclin fold protein 1cyclin-Xcyclin-box carrying protein 1
Modification date2020031320200313
UniProtAcc

Q96ST2

P0C7X3

Ensembl transtripts involved in fusion geneENST00000295321, ENST00000455721, 
ENST00000486662, 		ENST00000492478, 
ENST00000265375, ENST00000339497, 
ENST00000374704, ENST00000374706, 
Fusion gene scores* DoF score6 X 7 X 3=1268 X 9 X 5=360
# samples 710
** MAII scorelog2(7/126*10)=-0.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/360*10)=-1.84799690655495
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: IWS1 [Title/Abstract] AND CCNY [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointIWS1(128281252)-CCNY(35805451), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCCNY

GO:0000086

G2/M transition of mitotic cell cycle

20059949

TgeneCCNY

GO:0045737

positive regulation of cyclin-dependent protein serine/threonine kinase activity

19524571|20059949

TgeneCCNY

GO:0060828

regulation of canonical Wnt signaling pathway

20059949


check buttonFusion gene breakpoints across IWS1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CCNY (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-8059-01AIWS1chr2

128281252

-CCNYchr10

35805451

+


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Fusion Gene ORF analysis for IWS1-CCNY

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000295321ENST00000492478IWS1chr2

128281252

-CCNYchr10

35805451

+
5CDS-3UTRENST00000455721ENST00000492478IWS1chr2

128281252

-CCNYchr10

35805451

+
In-frameENST00000295321ENST00000265375IWS1chr2

128281252

-CCNYchr10

35805451

+
In-frameENST00000295321ENST00000339497IWS1chr2

128281252

-CCNYchr10

35805451

+
In-frameENST00000295321ENST00000374704IWS1chr2

128281252

-CCNYchr10

35805451

+
In-frameENST00000295321ENST00000374706IWS1chr2

128281252

-CCNYchr10

35805451

+
In-frameENST00000455721ENST00000265375IWS1chr2

128281252

-CCNYchr10

35805451

+
In-frameENST00000455721ENST00000339497IWS1chr2

128281252

-CCNYchr10

35805451

+
In-frameENST00000455721ENST00000374704IWS1chr2

128281252

-CCNYchr10

35805451

+
In-frameENST00000455721ENST00000374706IWS1chr2

128281252

-CCNYchr10

35805451

+
intron-3CDSENST00000486662ENST00000265375IWS1chr2

128281252

-CCNYchr10

35805451

+
intron-3CDSENST00000486662ENST00000339497IWS1chr2

128281252

-CCNYchr10

35805451

+
intron-3CDSENST00000486662ENST00000374704IWS1chr2

128281252

-CCNYchr10

35805451

+
intron-3CDSENST00000486662ENST00000374706IWS1chr2

128281252

-CCNYchr10

35805451

+
intron-3UTRENST00000486662ENST00000492478IWS1chr2

128281252

-CCNYchr10

35805451

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000295321IWS1chr2128281252-ENST00000374706CCNYchr1035805451+39264102601171303
ENST00000295321IWS1chr2128281252-ENST00000265375CCNYchr1035805451+39144102601171303
ENST00000295321IWS1chr2128281252-ENST00000339497CCNYchr1035805451+39144102601171303
ENST00000295321IWS1chr2128281252-ENST00000374704CCNYchr1035805451+39264102601171303
ENST00000455721IWS1chr2128281252-ENST00000374706CCNYchr1035805451+37322163977324
ENST00000455721IWS1chr2128281252-ENST00000265375CCNYchr1035805451+37202163977324
ENST00000455721IWS1chr2128281252-ENST00000339497CCNYchr1035805451+37202163977324
ENST00000455721IWS1chr2128281252-ENST00000374704CCNYchr1035805451+37322163977324

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000295321ENST00000374706IWS1chr2128281252-CCNYchr1035805451+0.0007409050.99925905
ENST00000295321ENST00000265375IWS1chr2128281252-CCNYchr1035805451+0.0007186290.99928135
ENST00000295321ENST00000339497IWS1chr2128281252-CCNYchr1035805451+0.0007186290.99928135
ENST00000295321ENST00000374704IWS1chr2128281252-CCNYchr1035805451+0.0007409050.99925905
ENST00000455721ENST00000374706IWS1chr2128281252-CCNYchr1035805451+0.0001934430.9998066
ENST00000455721ENST00000265375IWS1chr2128281252-CCNYchr1035805451+0.0001885590.9998115
ENST00000455721ENST00000339497IWS1chr2128281252-CCNYchr1035805451+0.0001885590.9998115
ENST00000455721ENST00000374704IWS1chr2128281252-CCNYchr1035805451+0.0001934430.9998066

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Fusion Genomic Features for IWS1-CCNY


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
IWS1chr2128281251-CCNYchr1035805450+1.83E-050.99998164
IWS1chr2128281251-CCNYchr1035805450+1.83E-050.99998164

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for IWS1-CCNY


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:128281252/chr10:35805451)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
IWS1

Q96ST2

CCNY

P0C7X3

FUNCTION: Transcription factor which plays a key role in defining the composition of the RNA polymerase II (RNAPII) elongation complex and in modulating the production of mature mRNA transcripts. Acts as an assembly factor to recruit various factors to the RNAPII elongation complex and is recruited to the complex via binding to the transcription elongation factor SUPT6H bound to the C-terminal domain (CTD) of the RNAPII subunit RPB1 (POLR2A). The SUPT6H:IWS1:CTD complex recruits mRNA export factors (ALYREF/THOC4, EXOSC10) as well as histone modifying enzymes (such as SETD2) to ensure proper mRNA splicing, efficient mRNA export and elongation-coupled H3K36 methylation, a signature chromatin mark of active transcription. {ECO:0000269|PubMed:17184735, ECO:0000269|PubMed:17234882, ECO:0000269|PubMed:19141475}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCCNYchr2:128281252chr10:35805451ENST00000265375210143_26534288.0DomainNote=Cyclin N-terminal
TgeneCCNYchr2:128281252chr10:35805451ENST0000033949719143_26563317.0DomainNote=Cyclin N-terminal
TgeneCCNYchr2:128281252chr10:35805451ENST00000374704210143_26588342.0DomainNote=Cyclin N-terminal
TgeneCCNYchr2:128281252chr10:35805451ENST00000374706412143_26534288.0DomainNote=Cyclin N-terminal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneIWS1chr2:128281252chr10:35805451ENST00000295321-21483_50950820.0Compositional biasNote=Glu-rich
HgeneIWS1chr2:128281252chr10:35805451ENST00000295321-214614_69250820.0DomainTFIIS N-terminal
HgeneIWS1chr2:128281252chr10:35805451ENST00000295321-214469_49550820.0MotifIntegrase domain-binding motif (IBM)
HgeneIWS1chr2:128281252chr10:35805451ENST00000295321-214235_29650820.0RegionNote=3 X approximate tandem repeats
HgeneIWS1chr2:128281252chr10:35805451ENST00000295321-214235_26050820.0RepeatNote=1
HgeneIWS1chr2:128281252chr10:35805451ENST00000295321-214261_28650820.0RepeatNote=2
HgeneIWS1chr2:128281252chr10:35805451ENST00000295321-214287_29650820.0RepeatNote=3%3B half-length


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Fusion Gene Sequence for IWS1-CCNY


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>40796_40796_1_IWS1-CCNY_IWS1_chr2_128281252_ENST00000295321_CCNY_chr10_35805451_ENST00000265375_length(transcript)=3914nt_BP=410nt
GGTGCTTCTAGGAAGTAGAACGCCGGCTCGCATGCCTGCCCGCCCGCCAGCCTGCCGGGTACGGCCTTTTCCGCCGGGGCTTCCAGGTCA
AAGAATTCGCCTTTGCCGCTACCGCTTTCTTACCCTCCGCACCCGTTAAGTTCTCCGGTCGGGCGGCAGTCTCTGAACACTTAGCCGCGC
CATCCGGGGTCACACCGCCTGGAAGGAGGTGACGGGGGCGGCGCGGGGCGCGGACACTCCCCGCTGAGAGTCCGCCTGCCATGGACTCGG
AATATTACAGCGGCGACCAGTCAGATGATGGTGGTGCTACCCCAGTACAGGATGAACGGGATTCAGGGTCAGACGGTGAGGATGATGTAA
ATGAGCAACACTCCGGATCAGACACTGGAAGTGTAGAACGTCATTCAGAGCATCCTCCAGGACAAATAGCAAGGAAATACAGTTCCTGCT
CCACCATTTTCCTAGATGATAGCACAGTCAGTCAACCAAACCTCAAGTATACAATTAAATGTGTCGCTCTTGCAATATATTATCACATCA
AAAACAGGGACCCAGATGGAAGGATGCTCTTAGATATTTTTGATGAAAATCTTCACCCTCTTTCGAAATCCGAAGTGCCACCAGATTATG
ACAAACACAACCCAGAGCAGAAGCAGATTTACCGGTTCGTTCGGACACTGTTCAGTGCTGCTCAGCTGACGGCTGAATGTGCCATCGTCA
CCCTGGTGTACCTTGAAAGACTTTTAACATACGCAGAGATAGATATCTGTCCGGCCAACTGGAAGCGGATTGTTTTAGGGGCGATCCTGC
TGGCCTCCAAGGTGTGGGATGACCAGGCTGTATGGAATGTGGATTACTGCCAGATCCTGAAAGACATCACGGTGGAGGACATGAACGAGC
TAGAGCGACAGTTTCTTGAATTGCTGCAGTTCAACATCAATGTTCCTTCCAGTGTCTATGCCAAGTATTATTTTGATCTTCGTTCTCTGG
CAGAAGCGAACAACCTGAGCTTTCCCTTGGAGCCCCTGAGCAGGGAGAGGGCTCACAAGCTTGAGGCCATCTCTCGCCTCTGCGAGGACA
AGTACAAGGACCTAAGAAGATCCGCGAGGAAGCGCTCAGCCAGTGCAGACAACCTGACTCTGCCCCGGTGGTCCCCAGCCATCATCTCTT
AACTACGGAGGCCCGCCGGAGGCCACACCATCCCTTAGTTTCTCCTTTAGTTTGAGAAAAGACAGACTTGGGGTGGGTTTGTTTTTGTTT
TTTCTTTCCTTTTCTTTTTTTACGCATAGCTCCGTCAAGCTGCCTGGATGAGCGCCCATGCAGCAAGGCTTGGAGGAAGCGTCAGTGCCC
TGGAGATCCCAGCTCGCTCTCCCCACTGTCAGCAACAGCACTTCCTTCGTGGAGGAAGTGGACTCGAATCCTGGAGGAGGAAATAAAGGG
AAAGGGAAGTCGTGGAGAGGCAGGGAAAATGGTTAAGCAGCCCGGCCCTCTGGAGTCCCCATGGGGGCGGTAGCTGAAGTTGGCGAGCGC
AGCGGTGGATGCAGAGCTGGCTGCACCCAGGGCTGGGCCAGTGTGTCCTGTAAGACTTCTTGCATTCCTTCTGCTGCTTTTTTGGGATGG
GGGTATTTTTGTTCATTTGTTTTTGCCCTGTTTTGATTTTGGTCCCACAGAGCAGGGGATGTAGTTTGTACCCACCATGGCGCAGACTTC
CAAATAAATAGTACTGGTCATTTCTCTCTGCACTATTTCTGCGCGCTGTCTTCTGAGCTTTCTTCCTCACCAGTGGGCTGTGCTTGTTCC
ATTTCTGTACACCCTTATTTTATACCGTTTTTCTTCAACAATGGCGAAATTGACTGTAGTGCTGAACCAAAAGTATCCCTTTCCCTCCTT
ATTCCTCACCCCAAGAACATTCTAGATCACATGGGTGCTTGTGCCTTCCGATTTTCTTGCATTTGTTTTTTTCCTGACCTGAAGTTGTTG
TTACAAAATCAGTCAGACTTTGTGGGCTGAAGGACACGGTGCAGCAGAGGGTGTCCCTGTGAGAGTTCTGCAGAGTGCTGGGCATGTGCC
TGGAACTACCGAGTAGGAGCCATTTCTTTGTACCCCTGCCTAATCCATTCCTCTCCTTCCAAGTCCATTGTTGCAAGCAATATTCTTCTC
AATTTTTATATGTTTACTTTAAATCAAAGTTAGTCTATTTGTATAAAATTTTTAAAAAATCTAAAAGAAAAAGAAAAAAAACAAGGGTGG
GTTGGGTATTCCAGTGGGAAGATCATTGAAGGGAAAAATGTTACTATTTACTGAGGTATTTTTCACAGAATGATTGAATTAAAAAAAACT
CAACTTGCATTTTCATTGTGGGTGCTTAGAGAAGTTCTACAAAATTCAAACTGTGAAGGTTTATGCTTCATTAATTATGACCATACTTTT
TCATTTTCTGACGATCCCTGATTTCCTTATGGACTCAATAAGAATCTTTTATATCAAGTAAAATGAAAGTTGATGATAGAATATCAAATA
GTGAATTTGATATGAAATCTAAGAGTGTGAGTCACTTGCATATGTAATGCTTTGGGTTTTTGCATATTTTCTTAGGTCACAGTGACAGGT
TTCTGAGTTGTTTCCCTTTTCAAGTCTCTGGGAGGCCAGTGGCAGCAGCAGGTCTGTGTTTCACCTTCTTCCCATGTGAGCTTGGAAAAC
TTTGGCATCTTAATTAGTCTTGAATCATACACCTGATCCCCAAACATTGCCTGCTCTCAATGAAACATGCTTTGGAAATGGAAGGGACTC
AGAAAGTCGAAATCCCAAGAACTCCAAGCCAAAAGTGTTAGGTTTTAGTGAAATTTGTGTCAGGTATAAGCATACCTGTTTGGGCCAGAA
TTATTATCACAGCCTTTCTGACCCAAACTTTCAAAAGCAAATAAACAGCATATAAAACGTTAATTATCTTTCCATTGTAATTGTGATGAT
CTACTCTGTATGGGTACCAAAATCACCTTCTCTCTTCAAGTCAAAGTTGAATTTAGAACTTTGAATACAGGTCAAAAAATGTAGAAAATA
TCATTTTATATTCCCTAATCTATATAGCTGAAAAAGGGTTGTATTTTCTTAGCTGAATATGAATACCTCTTAAACATAAATTAGTTCCTC
TCCAGTGAAGTATCTTATTTTACCAATCCATTTCAGGAAAGAGGTTCTGCTGCCGTAAAGGCAGAAATTTTATTTTTATCCCTTTTATTT
GAATGAGAGATTTGAAAATCGAATTATGTAAATATTTCAATGCATCTGCTATTATTTTGTGGAGTTTATTAAACTACTTTAAAAAAATTG
TATAGTCTATTTATTGTATGTATGTACATACAGTCTGATACCTAAAATTTAAAGTGGATTCCATAAAACCAGACTCAAGTCTTGTTTAGA
CTACTGAATACTGTTTTAGCCTGTGCCCTGGATTCTACCTCTGTATAGGAAAATTTTCCATATTCATTAATTAGTGTTGATCTGTATTAA
TTGGTTATGTTTCTTGCACTAAGGATGTTTAAAACTCCGCTGTAAGTGTAGATTTTAGTTTTACTGGCAGGATGAATCACTTGACACATA
GGTAGATACTTGAGGTTCATTTTCTTTTCTTTTTCTACATGATGATGAATAGTTATGTTTTCTTCTCTGATTTGTTCAAAGTTTGCCAAA
AGAAAACACAAAACCAGTACAGTACTTACTGATAAATCGTAGTGACTGTAATTTGTTTGTAAGGCGAATTAATGCTCTACAATTAAAGCT
GGATTACTATTGAGGAACACATTGTCTTAGTGTAGTTTTTGAATGGAAAGTTTTTGTCATTAAGGATGAAGGAAACGACACAATTTGTTA

>40796_40796_1_IWS1-CCNY_IWS1_chr2_128281252_ENST00000295321_CCNY_chr10_35805451_ENST00000265375_length(amino acids)=303AA_BP=50
MDSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSEHPPGQIARKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIY
YHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLG
AILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAHKLEAISRL

--------------------------------------------------------------
>40796_40796_2_IWS1-CCNY_IWS1_chr2_128281252_ENST00000295321_CCNY_chr10_35805451_ENST00000339497_length(transcript)=3914nt_BP=410nt
GGTGCTTCTAGGAAGTAGAACGCCGGCTCGCATGCCTGCCCGCCCGCCAGCCTGCCGGGTACGGCCTTTTCCGCCGGGGCTTCCAGGTCA
AAGAATTCGCCTTTGCCGCTACCGCTTTCTTACCCTCCGCACCCGTTAAGTTCTCCGGTCGGGCGGCAGTCTCTGAACACTTAGCCGCGC
CATCCGGGGTCACACCGCCTGGAAGGAGGTGACGGGGGCGGCGCGGGGCGCGGACACTCCCCGCTGAGAGTCCGCCTGCCATGGACTCGG
AATATTACAGCGGCGACCAGTCAGATGATGGTGGTGCTACCCCAGTACAGGATGAACGGGATTCAGGGTCAGACGGTGAGGATGATGTAA
ATGAGCAACACTCCGGATCAGACACTGGAAGTGTAGAACGTCATTCAGAGCATCCTCCAGGACAAATAGCAAGGAAATACAGTTCCTGCT
CCACCATTTTCCTAGATGATAGCACAGTCAGTCAACCAAACCTCAAGTATACAATTAAATGTGTCGCTCTTGCAATATATTATCACATCA
AAAACAGGGACCCAGATGGAAGGATGCTCTTAGATATTTTTGATGAAAATCTTCACCCTCTTTCGAAATCCGAAGTGCCACCAGATTATG
ACAAACACAACCCAGAGCAGAAGCAGATTTACCGGTTCGTTCGGACACTGTTCAGTGCTGCTCAGCTGACGGCTGAATGTGCCATCGTCA
CCCTGGTGTACCTTGAAAGACTTTTAACATACGCAGAGATAGATATCTGTCCGGCCAACTGGAAGCGGATTGTTTTAGGGGCGATCCTGC
TGGCCTCCAAGGTGTGGGATGACCAGGCTGTATGGAATGTGGATTACTGCCAGATCCTGAAAGACATCACGGTGGAGGACATGAACGAGC
TAGAGCGACAGTTTCTTGAATTGCTGCAGTTCAACATCAATGTTCCTTCCAGTGTCTATGCCAAGTATTATTTTGATCTTCGTTCTCTGG
CAGAAGCGAACAACCTGAGCTTTCCCTTGGAGCCCCTGAGCAGGGAGAGGGCTCACAAGCTTGAGGCCATCTCTCGCCTCTGCGAGGACA
AGTACAAGGACCTAAGAAGATCCGCGAGGAAGCGCTCAGCCAGTGCAGACAACCTGACTCTGCCCCGGTGGTCCCCAGCCATCATCTCTT
AACTACGGAGGCCCGCCGGAGGCCACACCATCCCTTAGTTTCTCCTTTAGTTTGAGAAAAGACAGACTTGGGGTGGGTTTGTTTTTGTTT
TTTCTTTCCTTTTCTTTTTTTACGCATAGCTCCGTCAAGCTGCCTGGATGAGCGCCCATGCAGCAAGGCTTGGAGGAAGCGTCAGTGCCC
TGGAGATCCCAGCTCGCTCTCCCCACTGTCAGCAACAGCACTTCCTTCGTGGAGGAAGTGGACTCGAATCCTGGAGGAGGAAATAAAGGG
AAAGGGAAGTCGTGGAGAGGCAGGGAAAATGGTTAAGCAGCCCGGCCCTCTGGAGTCCCCATGGGGGCGGTAGCTGAAGTTGGCGAGCGC
AGCGGTGGATGCAGAGCTGGCTGCACCCAGGGCTGGGCCAGTGTGTCCTGTAAGACTTCTTGCATTCCTTCTGCTGCTTTTTTGGGATGG
GGGTATTTTTGTTCATTTGTTTTTGCCCTGTTTTGATTTTGGTCCCACAGAGCAGGGGATGTAGTTTGTACCCACCATGGCGCAGACTTC
CAAATAAATAGTACTGGTCATTTCTCTCTGCACTATTTCTGCGCGCTGTCTTCTGAGCTTTCTTCCTCACCAGTGGGCTGTGCTTGTTCC
ATTTCTGTACACCCTTATTTTATACCGTTTTTCTTCAACAATGGCGAAATTGACTGTAGTGCTGAACCAAAAGTATCCCTTTCCCTCCTT
ATTCCTCACCCCAAGAACATTCTAGATCACATGGGTGCTTGTGCCTTCCGATTTTCTTGCATTTGTTTTTTTCCTGACCTGAAGTTGTTG
TTACAAAATCAGTCAGACTTTGTGGGCTGAAGGACACGGTGCAGCAGAGGGTGTCCCTGTGAGAGTTCTGCAGAGTGCTGGGCATGTGCC
TGGAACTACCGAGTAGGAGCCATTTCTTTGTACCCCTGCCTAATCCATTCCTCTCCTTCCAAGTCCATTGTTGCAAGCAATATTCTTCTC
AATTTTTATATGTTTACTTTAAATCAAAGTTAGTCTATTTGTATAAAATTTTTAAAAAATCTAAAAGAAAAAGAAAAAAAACAAGGGTGG
GTTGGGTATTCCAGTGGGAAGATCATTGAAGGGAAAAATGTTACTATTTACTGAGGTATTTTTCACAGAATGATTGAATTAAAAAAAACT
CAACTTGCATTTTCATTGTGGGTGCTTAGAGAAGTTCTACAAAATTCAAACTGTGAAGGTTTATGCTTCATTAATTATGACCATACTTTT
TCATTTTCTGACGATCCCTGATTTCCTTATGGACTCAATAAGAATCTTTTATATCAAGTAAAATGAAAGTTGATGATAGAATATCAAATA
GTGAATTTGATATGAAATCTAAGAGTGTGAGTCACTTGCATATGTAATGCTTTGGGTTTTTGCATATTTTCTTAGGTCACAGTGACAGGT
TTCTGAGTTGTTTCCCTTTTCAAGTCTCTGGGAGGCCAGTGGCAGCAGCAGGTCTGTGTTTCACCTTCTTCCCATGTGAGCTTGGAAAAC
TTTGGCATCTTAATTAGTCTTGAATCATACACCTGATCCCCAAACATTGCCTGCTCTCAATGAAACATGCTTTGGAAATGGAAGGGACTC
AGAAAGTCGAAATCCCAAGAACTCCAAGCCAAAAGTGTTAGGTTTTAGTGAAATTTGTGTCAGGTATAAGCATACCTGTTTGGGCCAGAA
TTATTATCACAGCCTTTCTGACCCAAACTTTCAAAAGCAAATAAACAGCATATAAAACGTTAATTATCTTTCCATTGTAATTGTGATGAT
CTACTCTGTATGGGTACCAAAATCACCTTCTCTCTTCAAGTCAAAGTTGAATTTAGAACTTTGAATACAGGTCAAAAAATGTAGAAAATA
TCATTTTATATTCCCTAATCTATATAGCTGAAAAAGGGTTGTATTTTCTTAGCTGAATATGAATACCTCTTAAACATAAATTAGTTCCTC
TCCAGTGAAGTATCTTATTTTACCAATCCATTTCAGGAAAGAGGTTCTGCTGCCGTAAAGGCAGAAATTTTATTTTTATCCCTTTTATTT
GAATGAGAGATTTGAAAATCGAATTATGTAAATATTTCAATGCATCTGCTATTATTTTGTGGAGTTTATTAAACTACTTTAAAAAAATTG
TATAGTCTATTTATTGTATGTATGTACATACAGTCTGATACCTAAAATTTAAAGTGGATTCCATAAAACCAGACTCAAGTCTTGTTTAGA
CTACTGAATACTGTTTTAGCCTGTGCCCTGGATTCTACCTCTGTATAGGAAAATTTTCCATATTCATTAATTAGTGTTGATCTGTATTAA
TTGGTTATGTTTCTTGCACTAAGGATGTTTAAAACTCCGCTGTAAGTGTAGATTTTAGTTTTACTGGCAGGATGAATCACTTGACACATA
GGTAGATACTTGAGGTTCATTTTCTTTTCTTTTTCTACATGATGATGAATAGTTATGTTTTCTTCTCTGATTTGTTCAAAGTTTGCCAAA
AGAAAACACAAAACCAGTACAGTACTTACTGATAAATCGTAGTGACTGTAATTTGTTTGTAAGGCGAATTAATGCTCTACAATTAAAGCT
GGATTACTATTGAGGAACACATTGTCTTAGTGTAGTTTTTGAATGGAAAGTTTTTGTCATTAAGGATGAAGGAAACGACACAATTTGTTA

>40796_40796_2_IWS1-CCNY_IWS1_chr2_128281252_ENST00000295321_CCNY_chr10_35805451_ENST00000339497_length(amino acids)=303AA_BP=50
MDSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSEHPPGQIARKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIY
YHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLG
AILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAHKLEAISRL

--------------------------------------------------------------
>40796_40796_3_IWS1-CCNY_IWS1_chr2_128281252_ENST00000295321_CCNY_chr10_35805451_ENST00000374704_length(transcript)=3926nt_BP=410nt
GGTGCTTCTAGGAAGTAGAACGCCGGCTCGCATGCCTGCCCGCCCGCCAGCCTGCCGGGTACGGCCTTTTCCGCCGGGGCTTCCAGGTCA
AAGAATTCGCCTTTGCCGCTACCGCTTTCTTACCCTCCGCACCCGTTAAGTTCTCCGGTCGGGCGGCAGTCTCTGAACACTTAGCCGCGC
CATCCGGGGTCACACCGCCTGGAAGGAGGTGACGGGGGCGGCGCGGGGCGCGGACACTCCCCGCTGAGAGTCCGCCTGCCATGGACTCGG
AATATTACAGCGGCGACCAGTCAGATGATGGTGGTGCTACCCCAGTACAGGATGAACGGGATTCAGGGTCAGACGGTGAGGATGATGTAA
ATGAGCAACACTCCGGATCAGACACTGGAAGTGTAGAACGTCATTCAGAGCATCCTCCAGGACAAATAGCAAGGAAATACAGTTCCTGCT
CCACCATTTTCCTAGATGATAGCACAGTCAGTCAACCAAACCTCAAGTATACAATTAAATGTGTCGCTCTTGCAATATATTATCACATCA
AAAACAGGGACCCAGATGGAAGGATGCTCTTAGATATTTTTGATGAAAATCTTCACCCTCTTTCGAAATCCGAAGTGCCACCAGATTATG
ACAAACACAACCCAGAGCAGAAGCAGATTTACCGGTTCGTTCGGACACTGTTCAGTGCTGCTCAGCTGACGGCTGAATGTGCCATCGTCA
CCCTGGTGTACCTTGAAAGACTTTTAACATACGCAGAGATAGATATCTGTCCGGCCAACTGGAAGCGGATTGTTTTAGGGGCGATCCTGC
TGGCCTCCAAGGTGTGGGATGACCAGGCTGTATGGAATGTGGATTACTGCCAGATCCTGAAAGACATCACGGTGGAGGACATGAACGAGC
TAGAGCGACAGTTTCTTGAATTGCTGCAGTTCAACATCAATGTTCCTTCCAGTGTCTATGCCAAGTATTATTTTGATCTTCGTTCTCTGG
CAGAAGCGAACAACCTGAGCTTTCCCTTGGAGCCCCTGAGCAGGGAGAGGGCTCACAAGCTTGAGGCCATCTCTCGCCTCTGCGAGGACA
AGTACAAGGACCTAAGAAGATCCGCGAGGAAGCGCTCAGCCAGTGCAGACAACCTGACTCTGCCCCGGTGGTCCCCAGCCATCATCTCTT
AACTACGGAGGCCCGCCGGAGGCCACACCATCCCTTAGTTTCTCCTTTAGTTTGAGAAAAGACAGACTTGGGGTGGGTTTGTTTTTGTTT
TTTCTTTCCTTTTCTTTTTTTACGCATAGCTCCGTCAAGCTGCCTGGATGAGCGCCCATGCAGCAAGGCTTGGAGGAAGCGTCAGTGCCC
TGGAGATCCCAGCTCGCTCTCCCCACTGTCAGCAACAGCACTTCCTTCGTGGAGGAAGTGGACTCGAATCCTGGAGGAGGAAATAAAGGG
AAAGGGAAGTCGTGGAGAGGCAGGGAAAATGGTTAAGCAGCCCGGCCCTCTGGAGTCCCCATGGGGGCGGTAGCTGAAGTTGGCGAGCGC
AGCGGTGGATGCAGAGCTGGCTGCACCCAGGGCTGGGCCAGTGTGTCCTGTAAGACTTCTTGCATTCCTTCTGCTGCTTTTTTGGGATGG
GGGTATTTTTGTTCATTTGTTTTTGCCCTGTTTTGATTTTGGTCCCACAGAGCAGGGGATGTAGTTTGTACCCACCATGGCGCAGACTTC
CAAATAAATAGTACTGGTCATTTCTCTCTGCACTATTTCTGCGCGCTGTCTTCTGAGCTTTCTTCCTCACCAGTGGGCTGTGCTTGTTCC
ATTTCTGTACACCCTTATTTTATACCGTTTTTCTTCAACAATGGCGAAATTGACTGTAGTGCTGAACCAAAAGTATCCCTTTCCCTCCTT
ATTCCTCACCCCAAGAACATTCTAGATCACATGGGTGCTTGTGCCTTCCGATTTTCTTGCATTTGTTTTTTTCCTGACCTGAAGTTGTTG
TTACAAAATCAGTCAGACTTTGTGGGCTGAAGGACACGGTGCAGCAGAGGGTGTCCCTGTGAGAGTTCTGCAGAGTGCTGGGCATGTGCC
TGGAACTACCGAGTAGGAGCCATTTCTTTGTACCCCTGCCTAATCCATTCCTCTCCTTCCAAGTCCATTGTTGCAAGCAATATTCTTCTC
AATTTTTATATGTTTACTTTAAATCAAAGTTAGTCTATTTGTATAAAATTTTTAAAAAATCTAAAAGAAAAAGAAAAAAAACAAGGGTGG
GTTGGGTATTCCAGTGGGAAGATCATTGAAGGGAAAAATGTTACTATTTACTGAGGTATTTTTCACAGAATGATTGAATTAAAAAAAACT
CAACTTGCATTTTCATTGTGGGTGCTTAGAGAAGTTCTACAAAATTCAAACTGTGAAGGTTTATGCTTCATTAATTATGACCATACTTTT
TCATTTTCTGACGATCCCTGATTTCCTTATGGACTCAATAAGAATCTTTTATATCAAGTAAAATGAAAGTTGATGATAGAATATCAAATA
GTGAATTTGATATGAAATCTAAGAGTGTGAGTCACTTGCATATGTAATGCTTTGGGTTTTTGCATATTTTCTTAGGTCACAGTGACAGGT
TTCTGAGTTGTTTCCCTTTTCAAGTCTCTGGGAGGCCAGTGGCAGCAGCAGGTCTGTGTTTCACCTTCTTCCCATGTGAGCTTGGAAAAC
TTTGGCATCTTAATTAGTCTTGAATCATACACCTGATCCCCAAACATTGCCTGCTCTCAATGAAACATGCTTTGGAAATGGAAGGGACTC
AGAAAGTCGAAATCCCAAGAACTCCAAGCCAAAAGTGTTAGGTTTTAGTGAAATTTGTGTCAGGTATAAGCATACCTGTTTGGGCCAGAA
TTATTATCACAGCCTTTCTGACCCAAACTTTCAAAAGCAAATAAACAGCATATAAAACGTTAATTATCTTTCCATTGTAATTGTGATGAT
CTACTCTGTATGGGTACCAAAATCACCTTCTCTCTTCAAGTCAAAGTTGAATTTAGAACTTTGAATACAGGTCAAAAAATGTAGAAAATA
TCATTTTATATTCCCTAATCTATATAGCTGAAAAAGGGTTGTATTTTCTTAGCTGAATATGAATACCTCTTAAACATAAATTAGTTCCTC
TCCAGTGAAGTATCTTATTTTACCAATCCATTTCAGGAAAGAGGTTCTGCTGCCGTAAAGGCAGAAATTTTATTTTTATCCCTTTTATTT
GAATGAGAGATTTGAAAATCGAATTATGTAAATATTTCAATGCATCTGCTATTATTTTGTGGAGTTTATTAAACTACTTTAAAAAAATTG
TATAGTCTATTTATTGTATGTATGTACATACAGTCTGATACCTAAAATTTAAAGTGGATTCCATAAAACCAGACTCAAGTCTTGTTTAGA
CTACTGAATACTGTTTTAGCCTGTGCCCTGGATTCTACCTCTGTATAGGAAAATTTTCCATATTCATTAATTAGTGTTGATCTGTATTAA
TTGGTTATGTTTCTTGCACTAAGGATGTTTAAAACTCCGCTGTAAGTGTAGATTTTAGTTTTACTGGCAGGATGAATCACTTGACACATA
GGTAGATACTTGAGGTTCATTTTCTTTTCTTTTTCTACATGATGATGAATAGTTATGTTTTCTTCTCTGATTTGTTCAAAGTTTGCCAAA
AGAAAACACAAAACCAGTACAGTACTTACTGATAAATCGTAGTGACTGTAATTTGTTTGTAAGGCGAATTAATGCTCTACAATTAAAGCT
GGATTACTATTGAGGAACACATTGTCTTAGTGTAGTTTTTGAATGGAAAGTTTTTGTCATTAAGGATGAAGGAAACGACACAATTTGTTA

>40796_40796_3_IWS1-CCNY_IWS1_chr2_128281252_ENST00000295321_CCNY_chr10_35805451_ENST00000374704_length(amino acids)=303AA_BP=50
MDSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSEHPPGQIARKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIY
YHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLG
AILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAHKLEAISRL

--------------------------------------------------------------
>40796_40796_4_IWS1-CCNY_IWS1_chr2_128281252_ENST00000295321_CCNY_chr10_35805451_ENST00000374706_length(transcript)=3926nt_BP=410nt
GGTGCTTCTAGGAAGTAGAACGCCGGCTCGCATGCCTGCCCGCCCGCCAGCCTGCCGGGTACGGCCTTTTCCGCCGGGGCTTCCAGGTCA
AAGAATTCGCCTTTGCCGCTACCGCTTTCTTACCCTCCGCACCCGTTAAGTTCTCCGGTCGGGCGGCAGTCTCTGAACACTTAGCCGCGC
CATCCGGGGTCACACCGCCTGGAAGGAGGTGACGGGGGCGGCGCGGGGCGCGGACACTCCCCGCTGAGAGTCCGCCTGCCATGGACTCGG
AATATTACAGCGGCGACCAGTCAGATGATGGTGGTGCTACCCCAGTACAGGATGAACGGGATTCAGGGTCAGACGGTGAGGATGATGTAA
ATGAGCAACACTCCGGATCAGACACTGGAAGTGTAGAACGTCATTCAGAGCATCCTCCAGGACAAATAGCAAGGAAATACAGTTCCTGCT
CCACCATTTTCCTAGATGATAGCACAGTCAGTCAACCAAACCTCAAGTATACAATTAAATGTGTCGCTCTTGCAATATATTATCACATCA
AAAACAGGGACCCAGATGGAAGGATGCTCTTAGATATTTTTGATGAAAATCTTCACCCTCTTTCGAAATCCGAAGTGCCACCAGATTATG
ACAAACACAACCCAGAGCAGAAGCAGATTTACCGGTTCGTTCGGACACTGTTCAGTGCTGCTCAGCTGACGGCTGAATGTGCCATCGTCA
CCCTGGTGTACCTTGAAAGACTTTTAACATACGCAGAGATAGATATCTGTCCGGCCAACTGGAAGCGGATTGTTTTAGGGGCGATCCTGC
TGGCCTCCAAGGTGTGGGATGACCAGGCTGTATGGAATGTGGATTACTGCCAGATCCTGAAAGACATCACGGTGGAGGACATGAACGAGC
TAGAGCGACAGTTTCTTGAATTGCTGCAGTTCAACATCAATGTTCCTTCCAGTGTCTATGCCAAGTATTATTTTGATCTTCGTTCTCTGG
CAGAAGCGAACAACCTGAGCTTTCCCTTGGAGCCCCTGAGCAGGGAGAGGGCTCACAAGCTTGAGGCCATCTCTCGCCTCTGCGAGGACA
AGTACAAGGACCTAAGAAGATCCGCGAGGAAGCGCTCAGCCAGTGCAGACAACCTGACTCTGCCCCGGTGGTCCCCAGCCATCATCTCTT
AACTACGGAGGCCCGCCGGAGGCCACACCATCCCTTAGTTTCTCCTTTAGTTTGAGAAAAGACAGACTTGGGGTGGGTTTGTTTTTGTTT
TTTCTTTCCTTTTCTTTTTTTACGCATAGCTCCGTCAAGCTGCCTGGATGAGCGCCCATGCAGCAAGGCTTGGAGGAAGCGTCAGTGCCC
TGGAGATCCCAGCTCGCTCTCCCCACTGTCAGCAACAGCACTTCCTTCGTGGAGGAAGTGGACTCGAATCCTGGAGGAGGAAATAAAGGG
AAAGGGAAGTCGTGGAGAGGCAGGGAAAATGGTTAAGCAGCCCGGCCCTCTGGAGTCCCCATGGGGGCGGTAGCTGAAGTTGGCGAGCGC
AGCGGTGGATGCAGAGCTGGCTGCACCCAGGGCTGGGCCAGTGTGTCCTGTAAGACTTCTTGCATTCCTTCTGCTGCTTTTTTGGGATGG
GGGTATTTTTGTTCATTTGTTTTTGCCCTGTTTTGATTTTGGTCCCACAGAGCAGGGGATGTAGTTTGTACCCACCATGGCGCAGACTTC
CAAATAAATAGTACTGGTCATTTCTCTCTGCACTATTTCTGCGCGCTGTCTTCTGAGCTTTCTTCCTCACCAGTGGGCTGTGCTTGTTCC
ATTTCTGTACACCCTTATTTTATACCGTTTTTCTTCAACAATGGCGAAATTGACTGTAGTGCTGAACCAAAAGTATCCCTTTCCCTCCTT
ATTCCTCACCCCAAGAACATTCTAGATCACATGGGTGCTTGTGCCTTCCGATTTTCTTGCATTTGTTTTTTTCCTGACCTGAAGTTGTTG
TTACAAAATCAGTCAGACTTTGTGGGCTGAAGGACACGGTGCAGCAGAGGGTGTCCCTGTGAGAGTTCTGCAGAGTGCTGGGCATGTGCC
TGGAACTACCGAGTAGGAGCCATTTCTTTGTACCCCTGCCTAATCCATTCCTCTCCTTCCAAGTCCATTGTTGCAAGCAATATTCTTCTC
AATTTTTATATGTTTACTTTAAATCAAAGTTAGTCTATTTGTATAAAATTTTTAAAAAATCTAAAAGAAAAAGAAAAAAAACAAGGGTGG
GTTGGGTATTCCAGTGGGAAGATCATTGAAGGGAAAAATGTTACTATTTACTGAGGTATTTTTCACAGAATGATTGAATTAAAAAAAACT
CAACTTGCATTTTCATTGTGGGTGCTTAGAGAAGTTCTACAAAATTCAAACTGTGAAGGTTTATGCTTCATTAATTATGACCATACTTTT
TCATTTTCTGACGATCCCTGATTTCCTTATGGACTCAATAAGAATCTTTTATATCAAGTAAAATGAAAGTTGATGATAGAATATCAAATA
GTGAATTTGATATGAAATCTAAGAGTGTGAGTCACTTGCATATGTAATGCTTTGGGTTTTTGCATATTTTCTTAGGTCACAGTGACAGGT
TTCTGAGTTGTTTCCCTTTTCAAGTCTCTGGGAGGCCAGTGGCAGCAGCAGGTCTGTGTTTCACCTTCTTCCCATGTGAGCTTGGAAAAC
TTTGGCATCTTAATTAGTCTTGAATCATACACCTGATCCCCAAACATTGCCTGCTCTCAATGAAACATGCTTTGGAAATGGAAGGGACTC
AGAAAGTCGAAATCCCAAGAACTCCAAGCCAAAAGTGTTAGGTTTTAGTGAAATTTGTGTCAGGTATAAGCATACCTGTTTGGGCCAGAA
TTATTATCACAGCCTTTCTGACCCAAACTTTCAAAAGCAAATAAACAGCATATAAAACGTTAATTATCTTTCCATTGTAATTGTGATGAT
CTACTCTGTATGGGTACCAAAATCACCTTCTCTCTTCAAGTCAAAGTTGAATTTAGAACTTTGAATACAGGTCAAAAAATGTAGAAAATA
TCATTTTATATTCCCTAATCTATATAGCTGAAAAAGGGTTGTATTTTCTTAGCTGAATATGAATACCTCTTAAACATAAATTAGTTCCTC
TCCAGTGAAGTATCTTATTTTACCAATCCATTTCAGGAAAGAGGTTCTGCTGCCGTAAAGGCAGAAATTTTATTTTTATCCCTTTTATTT
GAATGAGAGATTTGAAAATCGAATTATGTAAATATTTCAATGCATCTGCTATTATTTTGTGGAGTTTATTAAACTACTTTAAAAAAATTG
TATAGTCTATTTATTGTATGTATGTACATACAGTCTGATACCTAAAATTTAAAGTGGATTCCATAAAACCAGACTCAAGTCTTGTTTAGA
CTACTGAATACTGTTTTAGCCTGTGCCCTGGATTCTACCTCTGTATAGGAAAATTTTCCATATTCATTAATTAGTGTTGATCTGTATTAA
TTGGTTATGTTTCTTGCACTAAGGATGTTTAAAACTCCGCTGTAAGTGTAGATTTTAGTTTTACTGGCAGGATGAATCACTTGACACATA
GGTAGATACTTGAGGTTCATTTTCTTTTCTTTTTCTACATGATGATGAATAGTTATGTTTTCTTCTCTGATTTGTTCAAAGTTTGCCAAA
AGAAAACACAAAACCAGTACAGTACTTACTGATAAATCGTAGTGACTGTAATTTGTTTGTAAGGCGAATTAATGCTCTACAATTAAAGCT
GGATTACTATTGAGGAACACATTGTCTTAGTGTAGTTTTTGAATGGAAAGTTTTTGTCATTAAGGATGAAGGAAACGACACAATTTGTTA

>40796_40796_4_IWS1-CCNY_IWS1_chr2_128281252_ENST00000295321_CCNY_chr10_35805451_ENST00000374706_length(amino acids)=303AA_BP=50
MDSEYYSGDQSDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSEHPPGQIARKYSSCSTIFLDDSTVSQPNLKYTIKCVALAIY
YHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLERLLTYAEIDICPANWKRIVLG
AILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNLSFPLEPLSRERAHKLEAISRL

--------------------------------------------------------------
>40796_40796_5_IWS1-CCNY_IWS1_chr2_128281252_ENST00000455721_CCNY_chr10_35805451_ENST00000265375_length(transcript)=3720nt_BP=216nt
ATTTTGGCCCCAGCGGTGCTTCTAGGAAGTAGAACGCCGGCTCGCATGCCTGCCCGCCCGCCAGCCTGCCGGGTACGGCCTTTTCCGCCG
GGGCTTCCAGATGATGGTGGTGCTACCCCAGTACAGGATGAACGGGATTCAGGGTCAGACGGTGAGGATGATGTAAATGAGCAACACTCC
GGATCAGACACTGGAAGTGTAGAACGTCATTCAGAGCATCCTCCAGGACAAATAGCAAGGAAATACAGTTCCTGCTCCACCATTTTCCTA
GATGATAGCACAGTCAGTCAACCAAACCTCAAGTATACAATTAAATGTGTCGCTCTTGCAATATATTATCACATCAAAAACAGGGACCCA
GATGGAAGGATGCTCTTAGATATTTTTGATGAAAATCTTCACCCTCTTTCGAAATCCGAAGTGCCACCAGATTATGACAAACACAACCCA
GAGCAGAAGCAGATTTACCGGTTCGTTCGGACACTGTTCAGTGCTGCTCAGCTGACGGCTGAATGTGCCATCGTCACCCTGGTGTACCTT
GAAAGACTTTTAACATACGCAGAGATAGATATCTGTCCGGCCAACTGGAAGCGGATTGTTTTAGGGGCGATCCTGCTGGCCTCCAAGGTG
TGGGATGACCAGGCTGTATGGAATGTGGATTACTGCCAGATCCTGAAAGACATCACGGTGGAGGACATGAACGAGCTAGAGCGACAGTTT
CTTGAATTGCTGCAGTTCAACATCAATGTTCCTTCCAGTGTCTATGCCAAGTATTATTTTGATCTTCGTTCTCTGGCAGAAGCGAACAAC
CTGAGCTTTCCCTTGGAGCCCCTGAGCAGGGAGAGGGCTCACAAGCTTGAGGCCATCTCTCGCCTCTGCGAGGACAAGTACAAGGACCTA
AGAAGATCCGCGAGGAAGCGCTCAGCCAGTGCAGACAACCTGACTCTGCCCCGGTGGTCCCCAGCCATCATCTCTTAACTACGGAGGCCC
GCCGGAGGCCACACCATCCCTTAGTTTCTCCTTTAGTTTGAGAAAAGACAGACTTGGGGTGGGTTTGTTTTTGTTTTTTCTTTCCTTTTC
TTTTTTTACGCATAGCTCCGTCAAGCTGCCTGGATGAGCGCCCATGCAGCAAGGCTTGGAGGAAGCGTCAGTGCCCTGGAGATCCCAGCT
CGCTCTCCCCACTGTCAGCAACAGCACTTCCTTCGTGGAGGAAGTGGACTCGAATCCTGGAGGAGGAAATAAAGGGAAAGGGAAGTCGTG
GAGAGGCAGGGAAAATGGTTAAGCAGCCCGGCCCTCTGGAGTCCCCATGGGGGCGGTAGCTGAAGTTGGCGAGCGCAGCGGTGGATGCAG
AGCTGGCTGCACCCAGGGCTGGGCCAGTGTGTCCTGTAAGACTTCTTGCATTCCTTCTGCTGCTTTTTTGGGATGGGGGTATTTTTGTTC
ATTTGTTTTTGCCCTGTTTTGATTTTGGTCCCACAGAGCAGGGGATGTAGTTTGTACCCACCATGGCGCAGACTTCCAAATAAATAGTAC
TGGTCATTTCTCTCTGCACTATTTCTGCGCGCTGTCTTCTGAGCTTTCTTCCTCACCAGTGGGCTGTGCTTGTTCCATTTCTGTACACCC
TTATTTTATACCGTTTTTCTTCAACAATGGCGAAATTGACTGTAGTGCTGAACCAAAAGTATCCCTTTCCCTCCTTATTCCTCACCCCAA
GAACATTCTAGATCACATGGGTGCTTGTGCCTTCCGATTTTCTTGCATTTGTTTTTTTCCTGACCTGAAGTTGTTGTTACAAAATCAGTC
AGACTTTGTGGGCTGAAGGACACGGTGCAGCAGAGGGTGTCCCTGTGAGAGTTCTGCAGAGTGCTGGGCATGTGCCTGGAACTACCGAGT
AGGAGCCATTTCTTTGTACCCCTGCCTAATCCATTCCTCTCCTTCCAAGTCCATTGTTGCAAGCAATATTCTTCTCAATTTTTATATGTT
TACTTTAAATCAAAGTTAGTCTATTTGTATAAAATTTTTAAAAAATCTAAAAGAAAAAGAAAAAAAACAAGGGTGGGTTGGGTATTCCAG
TGGGAAGATCATTGAAGGGAAAAATGTTACTATTTACTGAGGTATTTTTCACAGAATGATTGAATTAAAAAAAACTCAACTTGCATTTTC
ATTGTGGGTGCTTAGAGAAGTTCTACAAAATTCAAACTGTGAAGGTTTATGCTTCATTAATTATGACCATACTTTTTCATTTTCTGACGA
TCCCTGATTTCCTTATGGACTCAATAAGAATCTTTTATATCAAGTAAAATGAAAGTTGATGATAGAATATCAAATAGTGAATTTGATATG
AAATCTAAGAGTGTGAGTCACTTGCATATGTAATGCTTTGGGTTTTTGCATATTTTCTTAGGTCACAGTGACAGGTTTCTGAGTTGTTTC
CCTTTTCAAGTCTCTGGGAGGCCAGTGGCAGCAGCAGGTCTGTGTTTCACCTTCTTCCCATGTGAGCTTGGAAAACTTTGGCATCTTAAT
TAGTCTTGAATCATACACCTGATCCCCAAACATTGCCTGCTCTCAATGAAACATGCTTTGGAAATGGAAGGGACTCAGAAAGTCGAAATC
CCAAGAACTCCAAGCCAAAAGTGTTAGGTTTTAGTGAAATTTGTGTCAGGTATAAGCATACCTGTTTGGGCCAGAATTATTATCACAGCC
TTTCTGACCCAAACTTTCAAAAGCAAATAAACAGCATATAAAACGTTAATTATCTTTCCATTGTAATTGTGATGATCTACTCTGTATGGG
TACCAAAATCACCTTCTCTCTTCAAGTCAAAGTTGAATTTAGAACTTTGAATACAGGTCAAAAAATGTAGAAAATATCATTTTATATTCC
CTAATCTATATAGCTGAAAAAGGGTTGTATTTTCTTAGCTGAATATGAATACCTCTTAAACATAAATTAGTTCCTCTCCAGTGAAGTATC
TTATTTTACCAATCCATTTCAGGAAAGAGGTTCTGCTGCCGTAAAGGCAGAAATTTTATTTTTATCCCTTTTATTTGAATGAGAGATTTG
AAAATCGAATTATGTAAATATTTCAATGCATCTGCTATTATTTTGTGGAGTTTATTAAACTACTTTAAAAAAATTGTATAGTCTATTTAT
TGTATGTATGTACATACAGTCTGATACCTAAAATTTAAAGTGGATTCCATAAAACCAGACTCAAGTCTTGTTTAGACTACTGAATACTGT
TTTAGCCTGTGCCCTGGATTCTACCTCTGTATAGGAAAATTTTCCATATTCATTAATTAGTGTTGATCTGTATTAATTGGTTATGTTTCT
TGCACTAAGGATGTTTAAAACTCCGCTGTAAGTGTAGATTTTAGTTTTACTGGCAGGATGAATCACTTGACACATAGGTAGATACTTGAG
GTTCATTTTCTTTTCTTTTTCTACATGATGATGAATAGTTATGTTTTCTTCTCTGATTTGTTCAAAGTTTGCCAAAAGAAAACACAAAAC
CAGTACAGTACTTACTGATAAATCGTAGTGACTGTAATTTGTTTGTAAGGCGAATTAATGCTCTACAATTAAAGCTGGATTACTATTGAG
GAACACATTGTCTTAGTGTAGTTTTTGAATGGAAAGTTTTTGTCATTAAGGATGAAGGAAACGACACAATTTGTTACTTTAATTTTATAT

>40796_40796_5_IWS1-CCNY_IWS1_chr2_128281252_ENST00000455721_CCNY_chr10_35805451_ENST00000265375_length(amino acids)=324AA_BP=71
MAPAVLLGSRTPARMPARPPACRVRPFPPGLPDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSEHPPGQIARKYSSCSTIFLD
DSTVSQPNLKYTIKCVALAIYYHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLE
RLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNL

--------------------------------------------------------------
>40796_40796_6_IWS1-CCNY_IWS1_chr2_128281252_ENST00000455721_CCNY_chr10_35805451_ENST00000339497_length(transcript)=3720nt_BP=216nt
ATTTTGGCCCCAGCGGTGCTTCTAGGAAGTAGAACGCCGGCTCGCATGCCTGCCCGCCCGCCAGCCTGCCGGGTACGGCCTTTTCCGCCG
GGGCTTCCAGATGATGGTGGTGCTACCCCAGTACAGGATGAACGGGATTCAGGGTCAGACGGTGAGGATGATGTAAATGAGCAACACTCC
GGATCAGACACTGGAAGTGTAGAACGTCATTCAGAGCATCCTCCAGGACAAATAGCAAGGAAATACAGTTCCTGCTCCACCATTTTCCTA
GATGATAGCACAGTCAGTCAACCAAACCTCAAGTATACAATTAAATGTGTCGCTCTTGCAATATATTATCACATCAAAAACAGGGACCCA
GATGGAAGGATGCTCTTAGATATTTTTGATGAAAATCTTCACCCTCTTTCGAAATCCGAAGTGCCACCAGATTATGACAAACACAACCCA
GAGCAGAAGCAGATTTACCGGTTCGTTCGGACACTGTTCAGTGCTGCTCAGCTGACGGCTGAATGTGCCATCGTCACCCTGGTGTACCTT
GAAAGACTTTTAACATACGCAGAGATAGATATCTGTCCGGCCAACTGGAAGCGGATTGTTTTAGGGGCGATCCTGCTGGCCTCCAAGGTG
TGGGATGACCAGGCTGTATGGAATGTGGATTACTGCCAGATCCTGAAAGACATCACGGTGGAGGACATGAACGAGCTAGAGCGACAGTTT
CTTGAATTGCTGCAGTTCAACATCAATGTTCCTTCCAGTGTCTATGCCAAGTATTATTTTGATCTTCGTTCTCTGGCAGAAGCGAACAAC
CTGAGCTTTCCCTTGGAGCCCCTGAGCAGGGAGAGGGCTCACAAGCTTGAGGCCATCTCTCGCCTCTGCGAGGACAAGTACAAGGACCTA
AGAAGATCCGCGAGGAAGCGCTCAGCCAGTGCAGACAACCTGACTCTGCCCCGGTGGTCCCCAGCCATCATCTCTTAACTACGGAGGCCC
GCCGGAGGCCACACCATCCCTTAGTTTCTCCTTTAGTTTGAGAAAAGACAGACTTGGGGTGGGTTTGTTTTTGTTTTTTCTTTCCTTTTC
TTTTTTTACGCATAGCTCCGTCAAGCTGCCTGGATGAGCGCCCATGCAGCAAGGCTTGGAGGAAGCGTCAGTGCCCTGGAGATCCCAGCT
CGCTCTCCCCACTGTCAGCAACAGCACTTCCTTCGTGGAGGAAGTGGACTCGAATCCTGGAGGAGGAAATAAAGGGAAAGGGAAGTCGTG
GAGAGGCAGGGAAAATGGTTAAGCAGCCCGGCCCTCTGGAGTCCCCATGGGGGCGGTAGCTGAAGTTGGCGAGCGCAGCGGTGGATGCAG
AGCTGGCTGCACCCAGGGCTGGGCCAGTGTGTCCTGTAAGACTTCTTGCATTCCTTCTGCTGCTTTTTTGGGATGGGGGTATTTTTGTTC
ATTTGTTTTTGCCCTGTTTTGATTTTGGTCCCACAGAGCAGGGGATGTAGTTTGTACCCACCATGGCGCAGACTTCCAAATAAATAGTAC
TGGTCATTTCTCTCTGCACTATTTCTGCGCGCTGTCTTCTGAGCTTTCTTCCTCACCAGTGGGCTGTGCTTGTTCCATTTCTGTACACCC
TTATTTTATACCGTTTTTCTTCAACAATGGCGAAATTGACTGTAGTGCTGAACCAAAAGTATCCCTTTCCCTCCTTATTCCTCACCCCAA
GAACATTCTAGATCACATGGGTGCTTGTGCCTTCCGATTTTCTTGCATTTGTTTTTTTCCTGACCTGAAGTTGTTGTTACAAAATCAGTC
AGACTTTGTGGGCTGAAGGACACGGTGCAGCAGAGGGTGTCCCTGTGAGAGTTCTGCAGAGTGCTGGGCATGTGCCTGGAACTACCGAGT
AGGAGCCATTTCTTTGTACCCCTGCCTAATCCATTCCTCTCCTTCCAAGTCCATTGTTGCAAGCAATATTCTTCTCAATTTTTATATGTT
TACTTTAAATCAAAGTTAGTCTATTTGTATAAAATTTTTAAAAAATCTAAAAGAAAAAGAAAAAAAACAAGGGTGGGTTGGGTATTCCAG
TGGGAAGATCATTGAAGGGAAAAATGTTACTATTTACTGAGGTATTTTTCACAGAATGATTGAATTAAAAAAAACTCAACTTGCATTTTC
ATTGTGGGTGCTTAGAGAAGTTCTACAAAATTCAAACTGTGAAGGTTTATGCTTCATTAATTATGACCATACTTTTTCATTTTCTGACGA
TCCCTGATTTCCTTATGGACTCAATAAGAATCTTTTATATCAAGTAAAATGAAAGTTGATGATAGAATATCAAATAGTGAATTTGATATG
AAATCTAAGAGTGTGAGTCACTTGCATATGTAATGCTTTGGGTTTTTGCATATTTTCTTAGGTCACAGTGACAGGTTTCTGAGTTGTTTC
CCTTTTCAAGTCTCTGGGAGGCCAGTGGCAGCAGCAGGTCTGTGTTTCACCTTCTTCCCATGTGAGCTTGGAAAACTTTGGCATCTTAAT
TAGTCTTGAATCATACACCTGATCCCCAAACATTGCCTGCTCTCAATGAAACATGCTTTGGAAATGGAAGGGACTCAGAAAGTCGAAATC
CCAAGAACTCCAAGCCAAAAGTGTTAGGTTTTAGTGAAATTTGTGTCAGGTATAAGCATACCTGTTTGGGCCAGAATTATTATCACAGCC
TTTCTGACCCAAACTTTCAAAAGCAAATAAACAGCATATAAAACGTTAATTATCTTTCCATTGTAATTGTGATGATCTACTCTGTATGGG
TACCAAAATCACCTTCTCTCTTCAAGTCAAAGTTGAATTTAGAACTTTGAATACAGGTCAAAAAATGTAGAAAATATCATTTTATATTCC
CTAATCTATATAGCTGAAAAAGGGTTGTATTTTCTTAGCTGAATATGAATACCTCTTAAACATAAATTAGTTCCTCTCCAGTGAAGTATC
TTATTTTACCAATCCATTTCAGGAAAGAGGTTCTGCTGCCGTAAAGGCAGAAATTTTATTTTTATCCCTTTTATTTGAATGAGAGATTTG
AAAATCGAATTATGTAAATATTTCAATGCATCTGCTATTATTTTGTGGAGTTTATTAAACTACTTTAAAAAAATTGTATAGTCTATTTAT
TGTATGTATGTACATACAGTCTGATACCTAAAATTTAAAGTGGATTCCATAAAACCAGACTCAAGTCTTGTTTAGACTACTGAATACTGT
TTTAGCCTGTGCCCTGGATTCTACCTCTGTATAGGAAAATTTTCCATATTCATTAATTAGTGTTGATCTGTATTAATTGGTTATGTTTCT
TGCACTAAGGATGTTTAAAACTCCGCTGTAAGTGTAGATTTTAGTTTTACTGGCAGGATGAATCACTTGACACATAGGTAGATACTTGAG
GTTCATTTTCTTTTCTTTTTCTACATGATGATGAATAGTTATGTTTTCTTCTCTGATTTGTTCAAAGTTTGCCAAAAGAAAACACAAAAC
CAGTACAGTACTTACTGATAAATCGTAGTGACTGTAATTTGTTTGTAAGGCGAATTAATGCTCTACAATTAAAGCTGGATTACTATTGAG
GAACACATTGTCTTAGTGTAGTTTTTGAATGGAAAGTTTTTGTCATTAAGGATGAAGGAAACGACACAATTTGTTACTTTAATTTTATAT

>40796_40796_6_IWS1-CCNY_IWS1_chr2_128281252_ENST00000455721_CCNY_chr10_35805451_ENST00000339497_length(amino acids)=324AA_BP=71
MAPAVLLGSRTPARMPARPPACRVRPFPPGLPDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSEHPPGQIARKYSSCSTIFLD
DSTVSQPNLKYTIKCVALAIYYHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLE
RLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNL

--------------------------------------------------------------
>40796_40796_7_IWS1-CCNY_IWS1_chr2_128281252_ENST00000455721_CCNY_chr10_35805451_ENST00000374704_length(transcript)=3732nt_BP=216nt
ATTTTGGCCCCAGCGGTGCTTCTAGGAAGTAGAACGCCGGCTCGCATGCCTGCCCGCCCGCCAGCCTGCCGGGTACGGCCTTTTCCGCCG
GGGCTTCCAGATGATGGTGGTGCTACCCCAGTACAGGATGAACGGGATTCAGGGTCAGACGGTGAGGATGATGTAAATGAGCAACACTCC
GGATCAGACACTGGAAGTGTAGAACGTCATTCAGAGCATCCTCCAGGACAAATAGCAAGGAAATACAGTTCCTGCTCCACCATTTTCCTA
GATGATAGCACAGTCAGTCAACCAAACCTCAAGTATACAATTAAATGTGTCGCTCTTGCAATATATTATCACATCAAAAACAGGGACCCA
GATGGAAGGATGCTCTTAGATATTTTTGATGAAAATCTTCACCCTCTTTCGAAATCCGAAGTGCCACCAGATTATGACAAACACAACCCA
GAGCAGAAGCAGATTTACCGGTTCGTTCGGACACTGTTCAGTGCTGCTCAGCTGACGGCTGAATGTGCCATCGTCACCCTGGTGTACCTT
GAAAGACTTTTAACATACGCAGAGATAGATATCTGTCCGGCCAACTGGAAGCGGATTGTTTTAGGGGCGATCCTGCTGGCCTCCAAGGTG
TGGGATGACCAGGCTGTATGGAATGTGGATTACTGCCAGATCCTGAAAGACATCACGGTGGAGGACATGAACGAGCTAGAGCGACAGTTT
CTTGAATTGCTGCAGTTCAACATCAATGTTCCTTCCAGTGTCTATGCCAAGTATTATTTTGATCTTCGTTCTCTGGCAGAAGCGAACAAC
CTGAGCTTTCCCTTGGAGCCCCTGAGCAGGGAGAGGGCTCACAAGCTTGAGGCCATCTCTCGCCTCTGCGAGGACAAGTACAAGGACCTA
AGAAGATCCGCGAGGAAGCGCTCAGCCAGTGCAGACAACCTGACTCTGCCCCGGTGGTCCCCAGCCATCATCTCTTAACTACGGAGGCCC
GCCGGAGGCCACACCATCCCTTAGTTTCTCCTTTAGTTTGAGAAAAGACAGACTTGGGGTGGGTTTGTTTTTGTTTTTTCTTTCCTTTTC
TTTTTTTACGCATAGCTCCGTCAAGCTGCCTGGATGAGCGCCCATGCAGCAAGGCTTGGAGGAAGCGTCAGTGCCCTGGAGATCCCAGCT
CGCTCTCCCCACTGTCAGCAACAGCACTTCCTTCGTGGAGGAAGTGGACTCGAATCCTGGAGGAGGAAATAAAGGGAAAGGGAAGTCGTG
GAGAGGCAGGGAAAATGGTTAAGCAGCCCGGCCCTCTGGAGTCCCCATGGGGGCGGTAGCTGAAGTTGGCGAGCGCAGCGGTGGATGCAG
AGCTGGCTGCACCCAGGGCTGGGCCAGTGTGTCCTGTAAGACTTCTTGCATTCCTTCTGCTGCTTTTTTGGGATGGGGGTATTTTTGTTC
ATTTGTTTTTGCCCTGTTTTGATTTTGGTCCCACAGAGCAGGGGATGTAGTTTGTACCCACCATGGCGCAGACTTCCAAATAAATAGTAC
TGGTCATTTCTCTCTGCACTATTTCTGCGCGCTGTCTTCTGAGCTTTCTTCCTCACCAGTGGGCTGTGCTTGTTCCATTTCTGTACACCC
TTATTTTATACCGTTTTTCTTCAACAATGGCGAAATTGACTGTAGTGCTGAACCAAAAGTATCCCTTTCCCTCCTTATTCCTCACCCCAA
GAACATTCTAGATCACATGGGTGCTTGTGCCTTCCGATTTTCTTGCATTTGTTTTTTTCCTGACCTGAAGTTGTTGTTACAAAATCAGTC
AGACTTTGTGGGCTGAAGGACACGGTGCAGCAGAGGGTGTCCCTGTGAGAGTTCTGCAGAGTGCTGGGCATGTGCCTGGAACTACCGAGT
AGGAGCCATTTCTTTGTACCCCTGCCTAATCCATTCCTCTCCTTCCAAGTCCATTGTTGCAAGCAATATTCTTCTCAATTTTTATATGTT
TACTTTAAATCAAAGTTAGTCTATTTGTATAAAATTTTTAAAAAATCTAAAAGAAAAAGAAAAAAAACAAGGGTGGGTTGGGTATTCCAG
TGGGAAGATCATTGAAGGGAAAAATGTTACTATTTACTGAGGTATTTTTCACAGAATGATTGAATTAAAAAAAACTCAACTTGCATTTTC
ATTGTGGGTGCTTAGAGAAGTTCTACAAAATTCAAACTGTGAAGGTTTATGCTTCATTAATTATGACCATACTTTTTCATTTTCTGACGA
TCCCTGATTTCCTTATGGACTCAATAAGAATCTTTTATATCAAGTAAAATGAAAGTTGATGATAGAATATCAAATAGTGAATTTGATATG
AAATCTAAGAGTGTGAGTCACTTGCATATGTAATGCTTTGGGTTTTTGCATATTTTCTTAGGTCACAGTGACAGGTTTCTGAGTTGTTTC
CCTTTTCAAGTCTCTGGGAGGCCAGTGGCAGCAGCAGGTCTGTGTTTCACCTTCTTCCCATGTGAGCTTGGAAAACTTTGGCATCTTAAT
TAGTCTTGAATCATACACCTGATCCCCAAACATTGCCTGCTCTCAATGAAACATGCTTTGGAAATGGAAGGGACTCAGAAAGTCGAAATC
CCAAGAACTCCAAGCCAAAAGTGTTAGGTTTTAGTGAAATTTGTGTCAGGTATAAGCATACCTGTTTGGGCCAGAATTATTATCACAGCC
TTTCTGACCCAAACTTTCAAAAGCAAATAAACAGCATATAAAACGTTAATTATCTTTCCATTGTAATTGTGATGATCTACTCTGTATGGG
TACCAAAATCACCTTCTCTCTTCAAGTCAAAGTTGAATTTAGAACTTTGAATACAGGTCAAAAAATGTAGAAAATATCATTTTATATTCC
CTAATCTATATAGCTGAAAAAGGGTTGTATTTTCTTAGCTGAATATGAATACCTCTTAAACATAAATTAGTTCCTCTCCAGTGAAGTATC
TTATTTTACCAATCCATTTCAGGAAAGAGGTTCTGCTGCCGTAAAGGCAGAAATTTTATTTTTATCCCTTTTATTTGAATGAGAGATTTG
AAAATCGAATTATGTAAATATTTCAATGCATCTGCTATTATTTTGTGGAGTTTATTAAACTACTTTAAAAAAATTGTATAGTCTATTTAT
TGTATGTATGTACATACAGTCTGATACCTAAAATTTAAAGTGGATTCCATAAAACCAGACTCAAGTCTTGTTTAGACTACTGAATACTGT
TTTAGCCTGTGCCCTGGATTCTACCTCTGTATAGGAAAATTTTCCATATTCATTAATTAGTGTTGATCTGTATTAATTGGTTATGTTTCT
TGCACTAAGGATGTTTAAAACTCCGCTGTAAGTGTAGATTTTAGTTTTACTGGCAGGATGAATCACTTGACACATAGGTAGATACTTGAG
GTTCATTTTCTTTTCTTTTTCTACATGATGATGAATAGTTATGTTTTCTTCTCTGATTTGTTCAAAGTTTGCCAAAAGAAAACACAAAAC
CAGTACAGTACTTACTGATAAATCGTAGTGACTGTAATTTGTTTGTAAGGCGAATTAATGCTCTACAATTAAAGCTGGATTACTATTGAG
GAACACATTGTCTTAGTGTAGTTTTTGAATGGAAAGTTTTTGTCATTAAGGATGAAGGAAACGACACAATTTGTTACTTTAATTTTATAT

>40796_40796_7_IWS1-CCNY_IWS1_chr2_128281252_ENST00000455721_CCNY_chr10_35805451_ENST00000374704_length(amino acids)=324AA_BP=71
MAPAVLLGSRTPARMPARPPACRVRPFPPGLPDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSEHPPGQIARKYSSCSTIFLD
DSTVSQPNLKYTIKCVALAIYYHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLE
RLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNL

--------------------------------------------------------------
>40796_40796_8_IWS1-CCNY_IWS1_chr2_128281252_ENST00000455721_CCNY_chr10_35805451_ENST00000374706_length(transcript)=3732nt_BP=216nt
ATTTTGGCCCCAGCGGTGCTTCTAGGAAGTAGAACGCCGGCTCGCATGCCTGCCCGCCCGCCAGCCTGCCGGGTACGGCCTTTTCCGCCG
GGGCTTCCAGATGATGGTGGTGCTACCCCAGTACAGGATGAACGGGATTCAGGGTCAGACGGTGAGGATGATGTAAATGAGCAACACTCC
GGATCAGACACTGGAAGTGTAGAACGTCATTCAGAGCATCCTCCAGGACAAATAGCAAGGAAATACAGTTCCTGCTCCACCATTTTCCTA
GATGATAGCACAGTCAGTCAACCAAACCTCAAGTATACAATTAAATGTGTCGCTCTTGCAATATATTATCACATCAAAAACAGGGACCCA
GATGGAAGGATGCTCTTAGATATTTTTGATGAAAATCTTCACCCTCTTTCGAAATCCGAAGTGCCACCAGATTATGACAAACACAACCCA
GAGCAGAAGCAGATTTACCGGTTCGTTCGGACACTGTTCAGTGCTGCTCAGCTGACGGCTGAATGTGCCATCGTCACCCTGGTGTACCTT
GAAAGACTTTTAACATACGCAGAGATAGATATCTGTCCGGCCAACTGGAAGCGGATTGTTTTAGGGGCGATCCTGCTGGCCTCCAAGGTG
TGGGATGACCAGGCTGTATGGAATGTGGATTACTGCCAGATCCTGAAAGACATCACGGTGGAGGACATGAACGAGCTAGAGCGACAGTTT
CTTGAATTGCTGCAGTTCAACATCAATGTTCCTTCCAGTGTCTATGCCAAGTATTATTTTGATCTTCGTTCTCTGGCAGAAGCGAACAAC
CTGAGCTTTCCCTTGGAGCCCCTGAGCAGGGAGAGGGCTCACAAGCTTGAGGCCATCTCTCGCCTCTGCGAGGACAAGTACAAGGACCTA
AGAAGATCCGCGAGGAAGCGCTCAGCCAGTGCAGACAACCTGACTCTGCCCCGGTGGTCCCCAGCCATCATCTCTTAACTACGGAGGCCC
GCCGGAGGCCACACCATCCCTTAGTTTCTCCTTTAGTTTGAGAAAAGACAGACTTGGGGTGGGTTTGTTTTTGTTTTTTCTTTCCTTTTC
TTTTTTTACGCATAGCTCCGTCAAGCTGCCTGGATGAGCGCCCATGCAGCAAGGCTTGGAGGAAGCGTCAGTGCCCTGGAGATCCCAGCT
CGCTCTCCCCACTGTCAGCAACAGCACTTCCTTCGTGGAGGAAGTGGACTCGAATCCTGGAGGAGGAAATAAAGGGAAAGGGAAGTCGTG
GAGAGGCAGGGAAAATGGTTAAGCAGCCCGGCCCTCTGGAGTCCCCATGGGGGCGGTAGCTGAAGTTGGCGAGCGCAGCGGTGGATGCAG
AGCTGGCTGCACCCAGGGCTGGGCCAGTGTGTCCTGTAAGACTTCTTGCATTCCTTCTGCTGCTTTTTTGGGATGGGGGTATTTTTGTTC
ATTTGTTTTTGCCCTGTTTTGATTTTGGTCCCACAGAGCAGGGGATGTAGTTTGTACCCACCATGGCGCAGACTTCCAAATAAATAGTAC
TGGTCATTTCTCTCTGCACTATTTCTGCGCGCTGTCTTCTGAGCTTTCTTCCTCACCAGTGGGCTGTGCTTGTTCCATTTCTGTACACCC
TTATTTTATACCGTTTTTCTTCAACAATGGCGAAATTGACTGTAGTGCTGAACCAAAAGTATCCCTTTCCCTCCTTATTCCTCACCCCAA
GAACATTCTAGATCACATGGGTGCTTGTGCCTTCCGATTTTCTTGCATTTGTTTTTTTCCTGACCTGAAGTTGTTGTTACAAAATCAGTC
AGACTTTGTGGGCTGAAGGACACGGTGCAGCAGAGGGTGTCCCTGTGAGAGTTCTGCAGAGTGCTGGGCATGTGCCTGGAACTACCGAGT
AGGAGCCATTTCTTTGTACCCCTGCCTAATCCATTCCTCTCCTTCCAAGTCCATTGTTGCAAGCAATATTCTTCTCAATTTTTATATGTT
TACTTTAAATCAAAGTTAGTCTATTTGTATAAAATTTTTAAAAAATCTAAAAGAAAAAGAAAAAAAACAAGGGTGGGTTGGGTATTCCAG
TGGGAAGATCATTGAAGGGAAAAATGTTACTATTTACTGAGGTATTTTTCACAGAATGATTGAATTAAAAAAAACTCAACTTGCATTTTC
ATTGTGGGTGCTTAGAGAAGTTCTACAAAATTCAAACTGTGAAGGTTTATGCTTCATTAATTATGACCATACTTTTTCATTTTCTGACGA
TCCCTGATTTCCTTATGGACTCAATAAGAATCTTTTATATCAAGTAAAATGAAAGTTGATGATAGAATATCAAATAGTGAATTTGATATG
AAATCTAAGAGTGTGAGTCACTTGCATATGTAATGCTTTGGGTTTTTGCATATTTTCTTAGGTCACAGTGACAGGTTTCTGAGTTGTTTC
CCTTTTCAAGTCTCTGGGAGGCCAGTGGCAGCAGCAGGTCTGTGTTTCACCTTCTTCCCATGTGAGCTTGGAAAACTTTGGCATCTTAAT
TAGTCTTGAATCATACACCTGATCCCCAAACATTGCCTGCTCTCAATGAAACATGCTTTGGAAATGGAAGGGACTCAGAAAGTCGAAATC
CCAAGAACTCCAAGCCAAAAGTGTTAGGTTTTAGTGAAATTTGTGTCAGGTATAAGCATACCTGTTTGGGCCAGAATTATTATCACAGCC
TTTCTGACCCAAACTTTCAAAAGCAAATAAACAGCATATAAAACGTTAATTATCTTTCCATTGTAATTGTGATGATCTACTCTGTATGGG
TACCAAAATCACCTTCTCTCTTCAAGTCAAAGTTGAATTTAGAACTTTGAATACAGGTCAAAAAATGTAGAAAATATCATTTTATATTCC
CTAATCTATATAGCTGAAAAAGGGTTGTATTTTCTTAGCTGAATATGAATACCTCTTAAACATAAATTAGTTCCTCTCCAGTGAAGTATC
TTATTTTACCAATCCATTTCAGGAAAGAGGTTCTGCTGCCGTAAAGGCAGAAATTTTATTTTTATCCCTTTTATTTGAATGAGAGATTTG
AAAATCGAATTATGTAAATATTTCAATGCATCTGCTATTATTTTGTGGAGTTTATTAAACTACTTTAAAAAAATTGTATAGTCTATTTAT
TGTATGTATGTACATACAGTCTGATACCTAAAATTTAAAGTGGATTCCATAAAACCAGACTCAAGTCTTGTTTAGACTACTGAATACTGT
TTTAGCCTGTGCCCTGGATTCTACCTCTGTATAGGAAAATTTTCCATATTCATTAATTAGTGTTGATCTGTATTAATTGGTTATGTTTCT
TGCACTAAGGATGTTTAAAACTCCGCTGTAAGTGTAGATTTTAGTTTTACTGGCAGGATGAATCACTTGACACATAGGTAGATACTTGAG
GTTCATTTTCTTTTCTTTTTCTACATGATGATGAATAGTTATGTTTTCTTCTCTGATTTGTTCAAAGTTTGCCAAAAGAAAACACAAAAC
CAGTACAGTACTTACTGATAAATCGTAGTGACTGTAATTTGTTTGTAAGGCGAATTAATGCTCTACAATTAAAGCTGGATTACTATTGAG
GAACACATTGTCTTAGTGTAGTTTTTGAATGGAAAGTTTTTGTCATTAAGGATGAAGGAAACGACACAATTTGTTACTTTAATTTTATAT

>40796_40796_8_IWS1-CCNY_IWS1_chr2_128281252_ENST00000455721_CCNY_chr10_35805451_ENST00000374706_length(amino acids)=324AA_BP=71
MAPAVLLGSRTPARMPARPPACRVRPFPPGLPDDGGATPVQDERDSGSDGEDDVNEQHSGSDTGSVERHSEHPPGQIARKYSSCSTIFLD
DSTVSQPNLKYTIKCVALAIYYHIKNRDPDGRMLLDIFDENLHPLSKSEVPPDYDKHNPEQKQIYRFVRTLFSAAQLTAECAIVTLVYLE
RLLTYAEIDICPANWKRIVLGAILLASKVWDDQAVWNVDYCQILKDITVEDMNELERQFLELLQFNINVPSSVYAKYYFDLRSLAEANNL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for IWS1-CCNY


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneIWS1chr2:128281252chr10:35805451ENST00000295321-214523_81950.0820.0SUPT6H and ALYREF


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for IWS1-CCNY


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for IWS1-CCNY


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource