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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:JARID2-HIVEP1 (FusionGDB2 ID:40888)

Fusion Gene Summary for JARID2-HIVEP1

check button Fusion gene summary
Fusion gene informationFusion gene name: JARID2-HIVEP1
Fusion gene ID: 40888
HgeneTgene
Gene symbol

JARID2

HIVEP1

Gene ID

3720

3096

Gene namejumonji and AT-rich interaction domain containing 2HIVEP zinc finger 1
SynonymsJMJCIRIP|CRYBP1|GAAP|MBP-1|PRDII-BF1|Schnurri-1|ZAS1|ZNF40|ZNF40A
Cytomap

6p22.3

6p24.1

Type of geneprotein-codingprotein-coding
Descriptionprotein Jumonjijumonji homologjumonji, AT rich interactive domain 2jumonji-like proteinjumonji/ARID domain-containing protein 2zinc finger protein 40cirhin interaction proteingate keeper of apoptosis-activating proteinhuman immunodeficiency virus type I enhancer binding protein 1major histocompatibility complex binding protein 1positive regulatory domain II binding factor 1
Modification date2020031320200313
UniProtAcc

Q92833

P15822

Ensembl transtripts involved in fusion geneENST00000474854, ENST00000341776, 
ENST00000397311, ENST00000541660, 
ENST00000379388, ENST00000484210, 
ENST00000541134, 
Fusion gene scores* DoF score17 X 5 X 11=9357 X 8 X 2=112
# samples 188
** MAII scorelog2(18/935*10)=-2.37696945844532
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/112*10)=-0.485426827170242
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: JARID2 [Title/Abstract] AND HIVEP1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointJARID2(15501640)-HIVEP1(12129992), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneHIVEP1

GO:0000122

negative regulation of transcription by RNA polymerase II

17008448

TgeneHIVEP1

GO:0030509

BMP signaling pathway

17008448

TgeneHIVEP1

GO:0045944

positive regulation of transcription by RNA polymerase II

17008448


check buttonFusion gene breakpoints across JARID2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across HIVEP1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-DK-AA76-01AJARID2chr6

15501640

-HIVEP1chr6

12129992

+


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Fusion Gene ORF analysis for JARID2-HIVEP1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000474854ENST00000379388JARID2chr6

15501640

-HIVEP1chr6

12129992

+
3UTR-intronENST00000474854ENST00000484210JARID2chr6

15501640

-HIVEP1chr6

12129992

+
3UTR-intronENST00000474854ENST00000541134JARID2chr6

15501640

-HIVEP1chr6

12129992

+
5CDS-intronENST00000341776ENST00000484210JARID2chr6

15501640

-HIVEP1chr6

12129992

+
5CDS-intronENST00000341776ENST00000541134JARID2chr6

15501640

-HIVEP1chr6

12129992

+
5CDS-intronENST00000397311ENST00000484210JARID2chr6

15501640

-HIVEP1chr6

12129992

+
5CDS-intronENST00000397311ENST00000541134JARID2chr6

15501640

-HIVEP1chr6

12129992

+
5CDS-intronENST00000541660ENST00000484210JARID2chr6

15501640

-HIVEP1chr6

12129992

+
5CDS-intronENST00000541660ENST00000541134JARID2chr6

15501640

-HIVEP1chr6

12129992

+
In-frameENST00000341776ENST00000379388JARID2chr6

15501640

-HIVEP1chr6

12129992

+
In-frameENST00000397311ENST00000379388JARID2chr6

15501640

-HIVEP1chr6

12129992

+
In-frameENST00000541660ENST00000379388JARID2chr6

15501640

-HIVEP1chr6

12129992

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000341776JARID2chr615501640-ENST00000379388HIVEP1chr612129992+5312269223247731513
ENST00000397311JARID2chr615501640-ENST00000379388HIVEP1chr612129992+507624561745371506
ENST00000541660JARID2chr615501640-ENST00000379388HIVEP1chr612129992+504724276345081481

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000341776ENST00000379388JARID2chr615501640-HIVEP1chr612129992+0.0023786430.99762136
ENST00000397311ENST00000379388JARID2chr615501640-HIVEP1chr612129992+0.0034830440.99651694
ENST00000541660ENST00000379388JARID2chr615501640-HIVEP1chr612129992+0.0022139260.99778605

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Fusion Genomic Features for JARID2-HIVEP1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for JARID2-HIVEP1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:15501640/chr6:12129992)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
JARID2

Q92833

HIVEP1

P15822

FUNCTION: Regulator of histone methyltransferase complexes that plays an essential role in embryonic development, including heart and liver development, neural tube fusion process and hematopoiesis (PubMed:20075857). Acts as an accessory subunit for the core PRC2 (Polycomb repressive complex 2) complex, which mediates histone H3K27 (H3K27me3) trimethylation on chromatin (PubMed:20075857, PubMed:29499137, PubMed:31959557). Binds DNA and mediates the recruitment of the PRC2 complex to target genes in embryonic stem cells, thereby playing a key role in stem cell differentiation and normal embryonic development (PubMed:20075857). In cardiac cells, it is required to repress expression of cyclin-D1 (CCND1) by activating methylation of 'Lys-9' of histone H3 (H3K9me) by the GLP1/EHMT1 and G9a/EHMT2 histone methyltransferases (By similarity). Also acts as a transcriptional repressor of ANF via its interaction with GATA4 and NKX2-5 (By similarity). Participates in the negative regulation of cell proliferation signaling (By similarity). Does not have histone demethylase activity (By similarity). {ECO:0000250|UniProtKB:Q62315, ECO:0000269|PubMed:20075857, ECO:0000269|PubMed:29499137, ECO:0000269|PubMed:31959557}.FUNCTION: This protein specifically binds to the DNA sequence 5'-GGGACTTTCC-3' which is found in the enhancer elements of numerous viral promoters such as those of SV40, CMV, or HIV-1. In addition, related sequences are found in the enhancer elements of a number of cellular promoters, including those of the class I MHC, interleukin-2 receptor, and interferon-beta genes. It may act in T-cell activation. Involved in activating HIV-1 gene expression. Isoform 2 and isoform 3 also bind to the IPCS (IRF1 and p53 common sequence) DNA sequence in the promoter region of interferon regulatory factor 1 and p53 genes and are involved in transcription regulation of these genes. Isoform 2 does not activate HIV-1 gene expression. Isoform 2 and isoform 3 may be involved in apoptosis.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneJARID2chr6:15501640chr6:12129992ENST00000341776-818557_5988161247.0DomainJmjN
HgeneJARID2chr6:15501640chr6:12129992ENST00000341776-818621_7138161247.0DomainARID
HgeneJARID2chr6:15501640chr6:12129992ENST00000397311-818557_5986441075.0DomainJmjN
HgeneJARID2chr6:15501640chr6:12129992ENST00000341776-818104_1108161247.0MotifNuclear localization signal
HgeneJARID2chr6:15501640chr6:12129992ENST00000397311-818104_1106441075.0MotifNuclear localization signal
TgeneHIVEP1chr6:15501640chr6:12129992ENST00000379388392088_211020252719.0Zinc fingerC2H2-type 3
TgeneHIVEP1chr6:15501640chr6:12129992ENST00000379388392116_214020252719.0Zinc fingerC2H2-type 4

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneJARID2chr6:15501640chr6:12129992ENST00000341776-8181234_12468161247.0Compositional biasNote=Poly-Ser
HgeneJARID2chr6:15501640chr6:12129992ENST00000397311-8181234_12466441075.0Compositional biasNote=Poly-Ser
HgeneJARID2chr6:15501640chr6:12129992ENST00000341776-818884_10488161247.0DomainJmjC
HgeneJARID2chr6:15501640chr6:12129992ENST00000397311-818621_7136441075.0DomainARID
HgeneJARID2chr6:15501640chr6:12129992ENST00000397311-818884_10486441075.0DomainJmjC
HgeneJARID2chr6:15501640chr6:12129992ENST00000341776-818874_8788161247.0MotifNote=GSGFP motif
HgeneJARID2chr6:15501640chr6:12129992ENST00000397311-818874_8786441075.0MotifNote=GSGFP motif
TgeneHIVEP1chr6:15501640chr6:12129992ENST0000037938839803_80620252719.0Compositional biasNote=Poly-Ser
TgeneHIVEP1chr6:15501640chr6:12129992ENST0000037938839406_42820252719.0Zinc fingerC2H2-type 1
TgeneHIVEP1chr6:15501640chr6:12129992ENST0000037938839434_45620252719.0Zinc fingerC2H2-type 2
TgeneHIVEP1chr6:15501640chr6:12129992ENST0000037938839956_98620252719.0Zinc fingerCCHC HIVEP-type


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Fusion Gene Sequence for JARID2-HIVEP1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>40888_40888_1_JARID2-HIVEP1_JARID2_chr6_15501640_ENST00000341776_HIVEP1_chr6_12129992_ENST00000379388_length(transcript)=5312nt_BP=2692nt
GTTTTACTAAAGTGAATTTTTTTTTGTTTGCTTCGTTCGTCTTTGGCTCTTTTTTTTTCCTTCCCAATTTCGGATTTATTTCAAGGCGAA
TCTGGCTTTGGGGGAAGAGGAAGAAAAGTCGGATTACAAGATCAACCACCACCAACAACAATAAAAACCACCAGGATATTTTTTTGCAAA
TTTCTGACGGCTTTAAATTCATGAAGCAATTGTCCCCTTTTGCAATCAGCATTTGGATCTCAGAATGAGCAAGGAAAGACCCAAGAGGAA
TATCATTCAGAAGAAATACGATGACAGTGATGGGATTCCGTGGTCAGAAGAACGGGTGGTACGTAAAGTCCTTTATTTGTCTCTGAAGGA
GTTCAAGAATTCCCAGAAGAGGCAGCATGCGGAAGGCATTGCTGGGAGCCTGAAAACTGTGAATGGGCTCCTTGGTAATGACCAGTCTAA
GGGATTAGGACCAGCATCAGAACAGTCAGAGAATGAAAAGGACGATGCATCCCAAGTGTCCTCCACTAGCAACGATGTTAGTTCTTCAGA
TTTTGAAGAAGGGCCGTCGAGGAAAAGGCCCAGGCTGCAAGCACAAAGGAAGTTTGCTCAGTCTCAGCCGAATAGTCCCAGCACAACTCC
AGTAAAGATAGTGGAGCCATTGCTACCCCCTCCAGCTACTCAGATATCAGACCTCTCTAAAAGGAAGCCTAAGACAGAAGATTTTCTTAC
CTTTCTCTGCCTTCGAGGTTCTCCTGCGCTGCCCAACAGCATGGTGTATTTTGGAAGCTCTCAGGATGAGGAGGAAGTCGAGGAGGAAGA
TGATGAGACAGAAGACGTCAAAACAGCCACCAACAATGCTTCATCTTCATGCCAGTCGACCCCCAGGAAAGGAAAAACCCACAAACATGT
TCACAACGGGCATGTTTTCAATGGTTCCAGCAGGTCAACACGGGAGAAGGAACCTGTTCAAAAACACAAAAGCAAAGAGGCCACTCCCGC
AAAGGAGAAGCACAGCGATCACCGGGCTGACAGCCGCCGGGAGCAGGCTTCAGCTAACCACCCCGCAGCGGCCCCCTCCACGGGTTCCTC
GGCCAAGGGGCTTGCTGCCACCCATCACCACCCCCCTCTGCATCGGTCGGCTCAGGACTTACGGAAACAGGTTTCTAAGGTAAACGGAGT
CACTCGAATGTCATCTCTGGGTGCAGGTGTAACCAGTGCCAAAAAGATGCGCGAGGTCAGACCTTCACCATCCAAAACTGTGAAGTACAC
TGCCACGGTGACGAAGGGGGCTGTCACATACACCAAAGCCAAGAGAGAACTGGTCAAGGACACCAAACCCAATCACCACAAGCCCAGTTC
CGCTGTCAACCACACAATCTCAGGGAAAACTGAAAGTAGCAATGCAAAAACCCGCAAACAGGTGCTATCCCTCGGGGGGGCGTCCAAGTC
CACTGGGCCCGCCGTCAATGGCCTCAAGGTCAGTGGCAGGTTGAACCCAAAGTCATGCACTAAGGAGGTGGGGGGGCGGCAGCTGCGGGA
GGGCCTGCAGCTGCGGGAGGGGCTGCGGAACTCCAAGAGGAGACTGGAAGAGGCACACCAGGCGGAGAAGCCGCAGTCGCCCCCCAAGAA
GATGAAAGGGGCGGCTGGCCCCGCCGAAGGCCCTGGCAAGAAGGCCCCGGCCGAGAGAGGTCTGCTGAACGGACACGTGAAGAAGGAAGT
GCCGGAGCGCAGTCTGGAGAGGAATCGGCCGAAGCGGGCCACGGCCGGGAAGAGCACGCCAGGCAGACAAGCACATGGCAAGGCGGACAG
CGCCTCCTGTGAAAATCGTTCTACCTCGCAACCGGAGTCCGTGCACAAGCCGCAGGACTCGGGCAAGGCCGAGAAGGGCGGCGGCAAGGC
CGGGTGGGCGGCCATGGACGAGATCCCCGTCCTCAGGCCCTCCGCCAAGGAGTTCCACGATCCGCTCATCTACATCGAGTCGGTCCGCGC
TCAGGTGGAGAAGTTCGGGATGTGCAGGGTGATCCCCCCTCCGGACTGGCGGCCCGAGTGCAAGCTCAACGATGAGATGCGGTTTGTCAC
GCAGATTCAGCACATCCACAAGCTGGGCCGGCGCTGGGGCCCCAACGTGCAGCGGCTGGCCTGCATCAAGAAGCACCTCAAATCTCAGGG
CATCACCATGGACGAGCTCCCGCTCATAGGGGGCTGTGAGCTCGACCTGGCCTGCTTTTTCCGGCTGATTAATGAGATGGGCGGCATGCA
GCAAGTGACTGACCTCAAAAAATGGAACAAACTAGCAGACATGCTGCGCATCCCCAGAACTGCCCAGGACCGGCTGGCCAAGCTGCAGGA
GGCCTACTGCCAGTACCTACTCTCCTACGACTCCCTGTCCCCAGAGGAGCACCGGCGGCTGGAGAAGGAGGTGCTGATGGAGAAGGAGAT
CCTGGAGAAGCGCAAGGGGCCGCTGGAAGGCCACACAGAGAACGACCACCACAAGTTCCACCCTCTGCCCCGCTTCGAGCCCAAGAATGG
GCTCATCCACGGCGTGGCCCCCAGGAACGGCTTCCGCAGCAAGCTCAAGGAGGTGGGCCAGGCCCAGTTGAAGACTGGCCGGCGGCGACT
CTTCGCTCAGGAAAAAGAAGTGGTCAAGGAAGAGGAGGAGGACAAAGGCGTCCTCAATGACTTCCACAAGTGCATCTATAAGAGAGCATT
AGGTAATCAAAAGTCCACAGTAGTTGAATTCAGCAATAAAGATGCCTCTGAAATTAACAGTGAGCAAGATAAAGAAAATTCCTTAATCAA
AAGTGAACCAAGAAGAATTAAAATATTTGATGGAGGATATAAGTCAAATGAAGAGTATGTATATGTCCGAGGCAGGGGAAGAGGAAAATA
CATTTGTGAAGAATGTGGAATACGTTGTAAGAAACCTAGCATGTTAAAGAAACACATACGAACCCATACAGATGTCCGCCCCTACCACTG
CACTTACTGTAACTTCTCCTTTAAGACTAAAGGAAATCTGACAAAACACATGAAGTCCAAGGCACATAGCAAGAAATGTGTGGATTTAGG
CGTCTCAGTAGGTTTAATAGATGAACAGGATACAGAAGAATCAGATGAAAAACAGAGATTCAGTTATGAGCGATCTGGATATGATCTTGA
AGAATCTGATGGCCCAGATGAGGATGACAATGAAAATGAAGACGATGATGAGGACAGCCAGGCTGAATCAGTCCTGTCAGCCACACCCTC
AGTCACAGCTAGCCCGCAGCACCTTCCATCTAGAAGTAGCCTTCAGGACCCTGTGAGTACTGACGAGGATGTCAGGATCACCGATTGCTT
TTCTGGGGTACACACGGACCCAATGGACGTTCTGCCCAGGGCGCTGCTCACCAGAATGACTGTCCTGAGCACAGCACAGTCTGACTACAA
TAGGAAGACACTCTCTCCGGGGAAGGCCAGGCAGCGTGCTGCGAGAGATGAAAACGACACAATTCCGTCTGTAGACACTTCCAGGTCCCC
GTGTCATCAGATGTCTGTGGACTACCCTGAGTCAGAAGAAATTCTGAGAAGTTCTATGGCAGGAAAAGCTGTTGCTATAACACAGAGCCC
ATCATCTGTAAGACTTCCTCCTGCTGCAGCTGAGCACAGCCCCCAGACAGCAGCGGGGATGCCTTCTGTGGCCTCACCACATCCTGACCC
TCAAGAACAGAAGCAGCAAATAACTCTACAGCCGACTCCAGGCTTGCCTTCTCCCCACACTCATTTGTTTAGCCACCTTCCTTTGCATTC
CCAGCAGCAATCGAGGACACCTTATAATATGGTTCCAGTTGGGGGGATCCATGTGGTACCTGCTGGCCTCACATACTCCACGTTTGTGCC
CCTTCAGGCTGGACCAGTGCAGCTCACGATCCCTGCTGTCAGTGTCGTTCACAGAACTTTGGGTACTCATAGGAATACGGTCACAGAAGT
GTCTGGCACTACAAACCCTGCTGGAGTGGCTGAATTAAGCAGTGTTGTGCCATGTATTCCTATCGGCCAAATCCGCGTGCCAGGCCTTCA
GAACCTAAGTACCCCAGGCTTGCAGTCACTCCCCTCGTTAAGCATGGAAACCGTCAATATTGTAGGCCTAGCCAATACAAATATGGCCCC
ACAAGTCCATCCACCAGGACTGGCTCTGAATGCTGTCGGACTGCAGGTTCTGACTGCAAACCCTTCATCACAAAGCAGCCCCGCCCCTCA
GGCACACATTCCAGGTCTCCAGATCTTGAACATAGCATTGCCCACCTTAATCCCCTCAGTCAGTCAAGTAGCCGTTGATGCACAGGGAGC
TCCAGAAATGCCAGCTTCCCAAAGCAAAGCATGCGAGACACAACCCAAGCAGACTTCTGTAGCCAGCGCAAACCAGGTCAGCAGGACCGA
GTCTCCTCAGGGGTTACCTACAGTCCAGCGGGAAAATGCAAAAAAAGTTCTGAATCCACCTGCCCCTGCAGGTGACCATGCAAGGCTTGA
TGGCCTGAGTAAAATGGACACAGAGAAGGCTGCCTCGGCAAATCACGTGAAGCCCAAGCCTGAACTCACTTCCATACAGGGCCAACCAGC
GTCCACGTCACAACCTCTGCTGAAGGCACATTCTGAAGTTTTTACAAAGCCCTCAGGCCAGCAGACTCTCTCTCCAGACAGACAGGTTCC
CAGGCCCACAGCACTACCGCGGAGGCAGCCCACTGTGCACTTCAGCGACGTGAGCAGCGATGATGACGAGGACAGGCTTGTGATAGCAAC
CTGATGGATTTTATTTTTTATTTGCTTTTTTTTTATATAACACTTAAAGGTTTCTTTGAAAACCCTCCTTTCCTTAAAGCACATTTTTCT
GACATAAACTCATGACTAATCTTTGTGCAATCATGAACTTTTGACCAATAATTGTTGTTTTGTGTCAGCTCCAGCCATTTTTGTACATGT
TGTATAGACAATTGTGCCTTTTAGGAGCTTTATGTTTAGAAACTGTACAGATTGTTGAATATCTATATACATAAAAATATATTATATATG
TATATGAAAACCAGGTAGTTATTTGTGTTTAGTAAGGAAAACCTGTCAAATAAATCAAATGATTAAATTATATGTTCCACTGTTGAATAT
AAATTTTATGGCTATGGGGCAGAGTTTCTGTGTATAAATTAGTATGTAAACTCCATATTTATTGTATTCATATTAGTCTTTGAAAATGGG
TCTGTCCTCCTTGTGTAAGACAGTAACTTTACACTTCAGACAGATTTTCTGTGTTATGAAATGTTTCAGTAAAATATTGTTTACTGACTT

>40888_40888_1_JARID2-HIVEP1_JARID2_chr6_15501640_ENST00000341776_HIVEP1_chr6_12129992_ENST00000379388_length(amino acids)=1513AA_BP=820
MDLRMSKERPKRNIIQKKYDDSDGIPWSEERVVRKVLYLSLKEFKNSQKRQHAEGIAGSLKTVNGLLGNDQSKGLGPASEQSENEKDDAS
QVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYF
GSSQDEEEVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRREQAS
ANHPAAAPSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKGAVTYTKAKREL
VKDTKPNHHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKRRLEE
AHQAEKPQSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENRSTSQPESVHKP
QDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQ
RLACIKKHLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEH
RRLEKEVLMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEEDKGV
LNDFHKCIYKRALGNQKSTVVEFSNKDASEINSEQDKENSLIKSEPRRIKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLKK
HIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLGVSVGLIDEQDTEESDEKQRFSYERSGYDLEESDGPDEDDNENEDDDE
DSQAESVLSATPSVTASPQHLPSRSSLQDPVSTDEDVRITDCFSGVHTDPMDVLPRALLTRMTVLSTAQSDYNRKTLSPGKARQRAARDE
NDTIPSVDTSRSPCHQMSVDYPESEEILRSSMAGKAVAITQSPSSVRLPPAAAEHSPQTAAGMPSVASPHPDPQEQKQQITLQPTPGLPS
PHTHLFSHLPLHSQQQSRTPYNMVPVGGIHVVPAGLTYSTFVPLQAGPVQLTIPAVSVVHRTLGTHRNTVTEVSGTTNPAGVAELSSVVP
CIPIGQIRVPGLQNLSTPGLQSLPSLSMETVNIVGLANTNMAPQVHPPGLALNAVGLQVLTANPSSQSSPAPQAHIPGLQILNIALPTLI
PSVSQVAVDAQGAPEMPASQSKACETQPKQTSVASANQVSRTESPQGLPTVQRENAKKVLNPPAPAGDHARLDGLSKMDTEKAASANHVK

--------------------------------------------------------------
>40888_40888_2_JARID2-HIVEP1_JARID2_chr6_15501640_ENST00000397311_HIVEP1_chr6_12129992_ENST00000379388_length(transcript)=5076nt_BP=2456nt
GAAGATGCGCTCGGCCTCTGCCTTCCGCTCCGGAGCGTCGCGCTTCCCACCAGGATGACAGTGATGGGATTCCGTGGTCAGAAGAACGGG
TGGTACGTAAAGTCCTTTATTTGTCTCTGAAGGAGTTCAAGAATTCCCAGAAGAGGCAGCATGCGGAAGGCATTGCTGGGAGCCTGAAAA
CTGTGAATGGGCTCCTTGGTAATGACCAGTCTAAGGGATTAGGACCAGCATCAGAACAGTCAGAGAATGAAAAGGACGATGCATCCCAAG
TGTCCTCCACTAGCAACGATGTTAGTTCTTCAGATTTTGAAGAAGGGCCGTCGAGGAAAAGGCCCAGGCTGCAAGCACAAAGGAAGTTTG
CTCAGTCTCAGCCGAATAGTCCCAGCACAACTCCAGTAAAGATAGTGGAGCCATTGCTACCCCCTCCAGCTACTCAGATATCAGACCTCT
CTAAAAGGAAGCCTAAGACAGAAGATTTTCTTACCTTTCTCTGCCTTCGAGGTTCTCCTGCGCTGCCCAACAGCATGGTGTATTTTGGAA
GCTCTCAGGATGAGGAGGAAGTCGAGGAGGAAGATGATGAGACAGAAGACGTCAAAACAGCCACCAACAATGCTTCATCTTCATGCCAGT
CGACCCCCAGGAAAGGAAAAACCCACAAACATGTTCACAACGGGCATGTTTTCAATGGTTCCAGCAGGTCAACACGGGAGAAGGAACCTG
TTCAAAAACACAAAAGCAAAGAGGCCACTCCCGCAAAGGAGAAGCACAGCGATCACCGGGCTGACAGCCGCCGGGAGCAGGCTTCAGCTA
ACCACCCCGCAGCGGCCCCCTCCACGGGTTCCTCGGCCAAGGGGCTTGCTGCCACCCATCACCACCCCCCTCTGCATCGGTCGGCTCAGG
ACTTACGGAAACAGGTTTCTAAGGTAAACGGAGTCACTCGAATGTCATCTCTGGGTGCAGGTGTAACCAGTGCCAAAAAGATGCGCGAGG
TCAGACCTTCACCATCCAAAACTGTGAAGTACACTGCCACGGTGACGAAGGGGGCTGTCACATACACCAAAGCCAAGAGAGAACTGGTCA
AGGACACCAAACCCAATCACCACAAGCCCAGTTCCGCTGTCAACCACACAATCTCAGGGAAAACTGAAAGTAGCAATGCAAAAACCCGCA
AACAGGTGCTATCCCTCGGGGGGGCGTCCAAGTCCACTGGGCCCGCCGTCAATGGCCTCAAGGTCAGTGGCAGGTTGAACCCAAAGTCAT
GCACTAAGGAGGTGGGGGGGCGGCAGCTGCGGGAGGGCCTGCAGCTGCGGGAGGGGCTGCGGAACTCCAAGAGGAGACTGGAAGAGGCAC
ACCAGGCGGAGAAGCCGCAGTCGCCCCCCAAGAAGATGAAAGGGGCGGCTGGCCCCGCCGAAGGCCCTGGCAAGAAGGCCCCGGCCGAGA
GAGGTCTGCTGAACGGACACGTGAAGAAGGAAGTGCCGGAGCGCAGTCTGGAGAGGAATCGGCCGAAGCGGGCCACGGCCGGGAAGAGCA
CGCCAGGCAGACAAGCACATGGCAAGGCGGACAGCGCCTCCTGTGAAAATCGTTCTACCTCGCAACCGGAGTCCGTGCACAAGCCGCAGG
ACTCGGGCAAGGCCGAGAAGGGCGGCGGCAAGGCCGGGTGGGCGGCCATGGACGAGATCCCCGTCCTCAGGCCCTCCGCCAAGGAGTTCC
ACGATCCGCTCATCTACATCGAGTCGGTCCGCGCTCAGGTGGAGAAGTTCGGGATGTGCAGGGTGATCCCCCCTCCGGACTGGCGGCCCG
AGTGCAAGCTCAACGATGAGATGCGGTTTGTCACGCAGATTCAGCACATCCACAAGCTGGGCCGGCGCTGGGGCCCCAACGTGCAGCGGC
TGGCCTGCATCAAGAAGCACCTCAAATCTCAGGGCATCACCATGGACGAGCTCCCGCTCATAGGGGGCTGTGAGCTCGACCTGGCCTGCT
TTTTCCGGCTGATTAATGAGATGGGCGGCATGCAGCAAGTGACTGACCTCAAAAAATGGAACAAACTAGCAGACATGCTGCGCATCCCCA
GAACTGCCCAGGACCGGCTGGCCAAGCTGCAGGAGGCCTACTGCCAGTACCTACTCTCCTACGACTCCCTGTCCCCAGAGGAGCACCGGC
GGCTGGAGAAGGAGGTGCTGATGGAGAAGGAGATCCTGGAGAAGCGCAAGGGGCCGCTGGAAGGCCACACAGAGAACGACCACCACAAGT
TCCACCCTCTGCCCCGCTTCGAGCCCAAGAATGGGCTCATCCACGGCGTGGCCCCCAGGAACGGCTTCCGCAGCAAGCTCAAGGAGGTGG
GCCAGGCCCAGTTGAAGACTGGCCGGCGGCGACTCTTCGCTCAGGAAAAAGAAGTGGTCAAGGAAGAGGAGGAGGACAAAGGCGTCCTCA
ATGACTTCCACAAGTGCATCTATAAGAGAGCATTAGGTAATCAAAAGTCCACAGTAGTTGAATTCAGCAATAAAGATGCCTCTGAAATTA
ACAGTGAGCAAGATAAAGAAAATTCCTTAATCAAAAGTGAACCAAGAAGAATTAAAATATTTGATGGAGGATATAAGTCAAATGAAGAGT
ATGTATATGTCCGAGGCAGGGGAAGAGGAAAATACATTTGTGAAGAATGTGGAATACGTTGTAAGAAACCTAGCATGTTAAAGAAACACA
TACGAACCCATACAGATGTCCGCCCCTACCACTGCACTTACTGTAACTTCTCCTTTAAGACTAAAGGAAATCTGACAAAACACATGAAGT
CCAAGGCACATAGCAAGAAATGTGTGGATTTAGGCGTCTCAGTAGGTTTAATAGATGAACAGGATACAGAAGAATCAGATGAAAAACAGA
GATTCAGTTATGAGCGATCTGGATATGATCTTGAAGAATCTGATGGCCCAGATGAGGATGACAATGAAAATGAAGACGATGATGAGGACA
GCCAGGCTGAATCAGTCCTGTCAGCCACACCCTCAGTCACAGCTAGCCCGCAGCACCTTCCATCTAGAAGTAGCCTTCAGGACCCTGTGA
GTACTGACGAGGATGTCAGGATCACCGATTGCTTTTCTGGGGTACACACGGACCCAATGGACGTTCTGCCCAGGGCGCTGCTCACCAGAA
TGACTGTCCTGAGCACAGCACAGTCTGACTACAATAGGAAGACACTCTCTCCGGGGAAGGCCAGGCAGCGTGCTGCGAGAGATGAAAACG
ACACAATTCCGTCTGTAGACACTTCCAGGTCCCCGTGTCATCAGATGTCTGTGGACTACCCTGAGTCAGAAGAAATTCTGAGAAGTTCTA
TGGCAGGAAAAGCTGTTGCTATAACACAGAGCCCATCATCTGTAAGACTTCCTCCTGCTGCAGCTGAGCACAGCCCCCAGACAGCAGCGG
GGATGCCTTCTGTGGCCTCACCACATCCTGACCCTCAAGAACAGAAGCAGCAAATAACTCTACAGCCGACTCCAGGCTTGCCTTCTCCCC
ACACTCATTTGTTTAGCCACCTTCCTTTGCATTCCCAGCAGCAATCGAGGACACCTTATAATATGGTTCCAGTTGGGGGGATCCATGTGG
TACCTGCTGGCCTCACATACTCCACGTTTGTGCCCCTTCAGGCTGGACCAGTGCAGCTCACGATCCCTGCTGTCAGTGTCGTTCACAGAA
CTTTGGGTACTCATAGGAATACGGTCACAGAAGTGTCTGGCACTACAAACCCTGCTGGAGTGGCTGAATTAAGCAGTGTTGTGCCATGTA
TTCCTATCGGCCAAATCCGCGTGCCAGGCCTTCAGAACCTAAGTACCCCAGGCTTGCAGTCACTCCCCTCGTTAAGCATGGAAACCGTCA
ATATTGTAGGCCTAGCCAATACAAATATGGCCCCACAAGTCCATCCACCAGGACTGGCTCTGAATGCTGTCGGACTGCAGGTTCTGACTG
CAAACCCTTCATCACAAAGCAGCCCCGCCCCTCAGGCACACATTCCAGGTCTCCAGATCTTGAACATAGCATTGCCCACCTTAATCCCCT
CAGTCAGTCAAGTAGCCGTTGATGCACAGGGAGCTCCAGAAATGCCAGCTTCCCAAAGCAAAGCATGCGAGACACAACCCAAGCAGACTT
CTGTAGCCAGCGCAAACCAGGTCAGCAGGACCGAGTCTCCTCAGGGGTTACCTACAGTCCAGCGGGAAAATGCAAAAAAAGTTCTGAATC
CACCTGCCCCTGCAGGTGACCATGCAAGGCTTGATGGCCTGAGTAAAATGGACACAGAGAAGGCTGCCTCGGCAAATCACGTGAAGCCCA
AGCCTGAACTCACTTCCATACAGGGCCAACCAGCGTCCACGTCACAACCTCTGCTGAAGGCACATTCTGAAGTTTTTACAAAGCCCTCAG
GCCAGCAGACTCTCTCTCCAGACAGACAGGTTCCCAGGCCCACAGCACTACCGCGGAGGCAGCCCACTGTGCACTTCAGCGACGTGAGCA
GCGATGATGACGAGGACAGGCTTGTGATAGCAACCTGATGGATTTTATTTTTTATTTGCTTTTTTTTTATATAACACTTAAAGGTTTCTT
TGAAAACCCTCCTTTCCTTAAAGCACATTTTTCTGACATAAACTCATGACTAATCTTTGTGCAATCATGAACTTTTGACCAATAATTGTT
GTTTTGTGTCAGCTCCAGCCATTTTTGTACATGTTGTATAGACAATTGTGCCTTTTAGGAGCTTTATGTTTAGAAACTGTACAGATTGTT
GAATATCTATATACATAAAAATATATTATATATGTATATGAAAACCAGGTAGTTATTTGTGTTTAGTAAGGAAAACCTGTCAAATAAATC
AAATGATTAAATTATATGTTCCACTGTTGAATATAAATTTTATGGCTATGGGGCAGAGTTTCTGTGTATAAATTAGTATGTAAACTCCAT
ATTTATTGTATTCATATTAGTCTTTGAAAATGGGTCTGTCCTCCTTGTGTAAGACAGTAACTTTACACTTCAGACAGATTTTCTGTGTTA

>40888_40888_2_JARID2-HIVEP1_JARID2_chr6_15501640_ENST00000397311_HIVEP1_chr6_12129992_ENST00000379388_length(amino acids)=1506AA_BP=813
MPSAPERRASHQDDSDGIPWSEERVVRKVLYLSLKEFKNSQKRQHAEGIAGSLKTVNGLLGNDQSKGLGPASEQSENEKDDASQVSSTSN
DVSSSDFEEGPSRKRPRLQAQRKFAQSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEE
EVEEEDDETEDVKTATNNASSSCQSTPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRREQASANHPAAA
PSTGSSAKGLAATHHHPPLHRSAQDLRKQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPN
HHKPSSAVNHTISGKTESSNAKTRKQVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKRRLEEAHQAEKP
QSPPKKMKGAAGPAEGPGKKAPAERGLLNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAE
KGGGKAGWAAMDEIPVLRPSAKEFHDPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKK
HLKSQGITMDELPLIGGCELDLACFFRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEV
LMEKEILEKRKGPLEGHTENDHHKFHPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEEDKGVLNDFHKC
IYKRALGNQKSTVVEFSNKDASEINSEQDKENSLIKSEPRRIKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTD
VRPYHCTYCNFSFKTKGNLTKHMKSKAHSKKCVDLGVSVGLIDEQDTEESDEKQRFSYERSGYDLEESDGPDEDDNENEDDDEDSQAESV
LSATPSVTASPQHLPSRSSLQDPVSTDEDVRITDCFSGVHTDPMDVLPRALLTRMTVLSTAQSDYNRKTLSPGKARQRAARDENDTIPSV
DTSRSPCHQMSVDYPESEEILRSSMAGKAVAITQSPSSVRLPPAAAEHSPQTAAGMPSVASPHPDPQEQKQQITLQPTPGLPSPHTHLFS
HLPLHSQQQSRTPYNMVPVGGIHVVPAGLTYSTFVPLQAGPVQLTIPAVSVVHRTLGTHRNTVTEVSGTTNPAGVAELSSVVPCIPIGQI
RVPGLQNLSTPGLQSLPSLSMETVNIVGLANTNMAPQVHPPGLALNAVGLQVLTANPSSQSSPAPQAHIPGLQILNIALPTLIPSVSQVA
VDAQGAPEMPASQSKACETQPKQTSVASANQVSRTESPQGLPTVQRENAKKVLNPPAPAGDHARLDGLSKMDTEKAASANHVKPKPELTS

--------------------------------------------------------------
>40888_40888_3_JARID2-HIVEP1_JARID2_chr6_15501640_ENST00000541660_HIVEP1_chr6_12129992_ENST00000379388_length(transcript)=5047nt_BP=2427nt
AAGTGCTCCGGAGCCTGCCTCACTGCGCTCTTCCTCCCTCCCTCCCTCTGTCCTTCTTCCTCTCTGTCTCTCTGCAATGATCCGGCTCTG
AGGATGGCTGCTCCACGGGTCTGTCAGGTGCAGTTTTTGGTGGCTTATCTTGAGGAACCTGGGATAGAAGGGCTCCTTGGTAATGACCAG
TCTAAGGGATTAGGACCAGCATCAGAACAGTCAGAGAATGAAAAGGACGATGCATCCCAAGTGTCCTCCACTAGCAACGATGTTAGTTCT
TCAGATTTTGAAGAAGGGCCGTCGAGGAAAAGGCCCAGGCTGCAAGCACAAAGGAAGTTTGCTCAGTCTCAGCCGAATAGTCCCAGCACA
ACTCCAGTAAAGATAGTGGAGCCATTGCTACCCCCTCCAGCTACTCAGATATCAGACCTCTCTAAAAGGAAGCCTAAGACAGAAGATTTT
CTTACCTTTCTCTGCCTTCGAGGTTCTCCTGCGCTGCCCAACAGCATGGTGTATTTTGGAAGCTCTCAGGATGAGGAGGAAGTCGAGGAG
GAAGATGATGAGACAGAAGACGTCAAAACAGCCACCAACAATGCTTCATCTTCATGCCAGTCGACCCCCAGGAAAGGAAAAACCCACAAA
CATGTTCACAACGGGCATGTTTTCAATGGTTCCAGCAGGTCAACACGGGAGAAGGAACCTGTTCAAAAACACAAAAGCAAAGAGGCCACT
CCCGCAAAGGAGAAGCACAGCGATCACCGGGCTGACAGCCGCCGGGAGCAGGCTTCAGCTAACCACCCCGCAGCGGCCCCCTCCACGGGT
TCCTCGGCCAAGGGGCTTGCTGCCACCCATCACCACCCCCCTCTGCATCGGTCGGCTCAGGACTTACGGAAACAGGTTTCTAAGGTAAAC
GGAGTCACTCGAATGTCATCTCTGGGTGCAGGTGTAACCAGTGCCAAAAAGATGCGCGAGGTCAGACCTTCACCATCCAAAACTGTGAAG
TACACTGCCACGGTGACGAAGGGGGCTGTCACATACACCAAAGCCAAGAGAGAACTGGTCAAGGACACCAAACCCAATCACCACAAGCCC
AGTTCCGCTGTCAACCACACAATCTCAGGGAAAACTGAAAGTAGCAATGCAAAAACCCGCAAACAGGTGCTATCCCTCGGGGGGGCGTCC
AAGTCCACTGGGCCCGCCGTCAATGGCCTCAAGGTCAGTGGCAGGTTGAACCCAAAGTCATGCACTAAGGAGGTGGGGGGGCGGCAGCTG
CGGGAGGGCCTGCAGCTGCGGGAGGGGCTGCGGAACTCCAAGAGGAGACTGGAAGAGGCACACCAGGCGGAGAAGCCGCAGTCGCCCCCC
AAGAAGATGAAAGGGGCGGCTGGCCCCGCCGAAGGCCCTGGCAAGAAGGCCCCGGCCGAGAGAGGTCTGCTGAACGGACACGTGAAGAAG
GAAGTGCCGGAGCGCAGTCTGGAGAGGAATCGGCCGAAGCGGGCCACGGCCGGGAAGAGCACGCCAGGCAGACAAGCACATGGCAAGGCG
GACAGCGCCTCCTGTGAAAATCGTTCTACCTCGCAACCGGAGTCCGTGCACAAGCCGCAGGACTCGGGCAAGGCCGAGAAGGGCGGCGGC
AAGGCCGGGTGGGCGGCCATGGACGAGATCCCCGTCCTCAGGCCCTCCGCCAAGGAGTTCCACGATCCGCTCATCTACATCGAGTCGGTC
CGCGCTCAGGTGGAGAAGTTCGGGATGTGCAGGGTGATCCCCCCTCCGGACTGGCGGCCCGAGTGCAAGCTCAACGATGAGATGCGGTTT
GTCACGCAGATTCAGCACATCCACAAGCTGGGCCGGCGCTGGGGCCCCAACGTGCAGCGGCTGGCCTGCATCAAGAAGCACCTCAAATCT
CAGGGCATCACCATGGACGAGCTCCCGCTCATAGGGGGCTGTGAGCTCGACCTGGCCTGCTTTTTCCGGCTGATTAATGAGATGGGCGGC
ATGCAGCAAGTGACTGACCTCAAAAAATGGAACAAACTAGCAGACATGCTGCGCATCCCCAGAACTGCCCAGGACCGGCTGGCCAAGCTG
CAGGAGGCCTACTGCCAGTACCTACTCTCCTACGACTCCCTGTCCCCAGAGGAGCACCGGCGGCTGGAGAAGGAGGTGCTGATGGAGAAG
GAGATCCTGGAGAAGCGCAAGGGGCCGCTGGAAGGCCACACAGAGAACGACCACCACAAGTTCCACCCTCTGCCCCGCTTCGAGCCCAAG
AATGGGCTCATCCACGGCGTGGCCCCCAGGAACGGCTTCCGCAGCAAGCTCAAGGAGGTGGGCCAGGCCCAGTTGAAGACTGGCCGGCGG
CGACTCTTCGCTCAGGAAAAAGAAGTGGTCAAGGAAGAGGAGGAGGACAAAGGCGTCCTCAATGACTTCCACAAGTGCATCTATAAGAGA
GCATTAGGTAATCAAAAGTCCACAGTAGTTGAATTCAGCAATAAAGATGCCTCTGAAATTAACAGTGAGCAAGATAAAGAAAATTCCTTA
ATCAAAAGTGAACCAAGAAGAATTAAAATATTTGATGGAGGATATAAGTCAAATGAAGAGTATGTATATGTCCGAGGCAGGGGAAGAGGA
AAATACATTTGTGAAGAATGTGGAATACGTTGTAAGAAACCTAGCATGTTAAAGAAACACATACGAACCCATACAGATGTCCGCCCCTAC
CACTGCACTTACTGTAACTTCTCCTTTAAGACTAAAGGAAATCTGACAAAACACATGAAGTCCAAGGCACATAGCAAGAAATGTGTGGAT
TTAGGCGTCTCAGTAGGTTTAATAGATGAACAGGATACAGAAGAATCAGATGAAAAACAGAGATTCAGTTATGAGCGATCTGGATATGAT
CTTGAAGAATCTGATGGCCCAGATGAGGATGACAATGAAAATGAAGACGATGATGAGGACAGCCAGGCTGAATCAGTCCTGTCAGCCACA
CCCTCAGTCACAGCTAGCCCGCAGCACCTTCCATCTAGAAGTAGCCTTCAGGACCCTGTGAGTACTGACGAGGATGTCAGGATCACCGAT
TGCTTTTCTGGGGTACACACGGACCCAATGGACGTTCTGCCCAGGGCGCTGCTCACCAGAATGACTGTCCTGAGCACAGCACAGTCTGAC
TACAATAGGAAGACACTCTCTCCGGGGAAGGCCAGGCAGCGTGCTGCGAGAGATGAAAACGACACAATTCCGTCTGTAGACACTTCCAGG
TCCCCGTGTCATCAGATGTCTGTGGACTACCCTGAGTCAGAAGAAATTCTGAGAAGTTCTATGGCAGGAAAAGCTGTTGCTATAACACAG
AGCCCATCATCTGTAAGACTTCCTCCTGCTGCAGCTGAGCACAGCCCCCAGACAGCAGCGGGGATGCCTTCTGTGGCCTCACCACATCCT
GACCCTCAAGAACAGAAGCAGCAAATAACTCTACAGCCGACTCCAGGCTTGCCTTCTCCCCACACTCATTTGTTTAGCCACCTTCCTTTG
CATTCCCAGCAGCAATCGAGGACACCTTATAATATGGTTCCAGTTGGGGGGATCCATGTGGTACCTGCTGGCCTCACATACTCCACGTTT
GTGCCCCTTCAGGCTGGACCAGTGCAGCTCACGATCCCTGCTGTCAGTGTCGTTCACAGAACTTTGGGTACTCATAGGAATACGGTCACA
GAAGTGTCTGGCACTACAAACCCTGCTGGAGTGGCTGAATTAAGCAGTGTTGTGCCATGTATTCCTATCGGCCAAATCCGCGTGCCAGGC
CTTCAGAACCTAAGTACCCCAGGCTTGCAGTCACTCCCCTCGTTAAGCATGGAAACCGTCAATATTGTAGGCCTAGCCAATACAAATATG
GCCCCACAAGTCCATCCACCAGGACTGGCTCTGAATGCTGTCGGACTGCAGGTTCTGACTGCAAACCCTTCATCACAAAGCAGCCCCGCC
CCTCAGGCACACATTCCAGGTCTCCAGATCTTGAACATAGCATTGCCCACCTTAATCCCCTCAGTCAGTCAAGTAGCCGTTGATGCACAG
GGAGCTCCAGAAATGCCAGCTTCCCAAAGCAAAGCATGCGAGACACAACCCAAGCAGACTTCTGTAGCCAGCGCAAACCAGGTCAGCAGG
ACCGAGTCTCCTCAGGGGTTACCTACAGTCCAGCGGGAAAATGCAAAAAAAGTTCTGAATCCACCTGCCCCTGCAGGTGACCATGCAAGG
CTTGATGGCCTGAGTAAAATGGACACAGAGAAGGCTGCCTCGGCAAATCACGTGAAGCCCAAGCCTGAACTCACTTCCATACAGGGCCAA
CCAGCGTCCACGTCACAACCTCTGCTGAAGGCACATTCTGAAGTTTTTACAAAGCCCTCAGGCCAGCAGACTCTCTCTCCAGACAGACAG
GTTCCCAGGCCCACAGCACTACCGCGGAGGCAGCCCACTGTGCACTTCAGCGACGTGAGCAGCGATGATGACGAGGACAGGCTTGTGATA
GCAACCTGATGGATTTTATTTTTTATTTGCTTTTTTTTTATATAACACTTAAAGGTTTCTTTGAAAACCCTCCTTTCCTTAAAGCACATT
TTTCTGACATAAACTCATGACTAATCTTTGTGCAATCATGAACTTTTGACCAATAATTGTTGTTTTGTGTCAGCTCCAGCCATTTTTGTA
CATGTTGTATAGACAATTGTGCCTTTTAGGAGCTTTATGTTTAGAAACTGTACAGATTGTTGAATATCTATATACATAAAAATATATTAT
ATATGTATATGAAAACCAGGTAGTTATTTGTGTTTAGTAAGGAAAACCTGTCAAATAAATCAAATGATTAAATTATATGTTCCACTGTTG
AATATAAATTTTATGGCTATGGGGCAGAGTTTCTGTGTATAAATTAGTATGTAAACTCCATATTTATTGTATTCATATTAGTCTTTGAAA
ATGGGTCTGTCCTCCTTGTGTAAGACAGTAACTTTACACTTCAGACAGATTTTCTGTGTTATGAAATGTTTCAGTAAAATATTGTTTACT

>40888_40888_3_JARID2-HIVEP1_JARID2_chr6_15501640_ENST00000541660_HIVEP1_chr6_12129992_ENST00000379388_length(amino acids)=1481AA_BP=788
MSLCNDPALRMAAPRVCQVQFLVAYLEEPGIEGLLGNDQSKGLGPASEQSENEKDDASQVSSTSNDVSSSDFEEGPSRKRPRLQAQRKFA
QSQPNSPSTTPVKIVEPLLPPPATQISDLSKRKPKTEDFLTFLCLRGSPALPNSMVYFGSSQDEEEVEEEDDETEDVKTATNNASSSCQS
TPRKGKTHKHVHNGHVFNGSSRSTREKEPVQKHKSKEATPAKEKHSDHRADSRREQASANHPAAAPSTGSSAKGLAATHHHPPLHRSAQD
LRKQVSKVNGVTRMSSLGAGVTSAKKMREVRPSPSKTVKYTATVTKGAVTYTKAKRELVKDTKPNHHKPSSAVNHTISGKTESSNAKTRK
QVLSLGGASKSTGPAVNGLKVSGRLNPKSCTKEVGGRQLREGLQLREGLRNSKRRLEEAHQAEKPQSPPKKMKGAAGPAEGPGKKAPAER
GLLNGHVKKEVPERSLERNRPKRATAGKSTPGRQAHGKADSASCENRSTSQPESVHKPQDSGKAEKGGGKAGWAAMDEIPVLRPSAKEFH
DPLIYIESVRAQVEKFGMCRVIPPPDWRPECKLNDEMRFVTQIQHIHKLGRRWGPNVQRLACIKKHLKSQGITMDELPLIGGCELDLACF
FRLINEMGGMQQVTDLKKWNKLADMLRIPRTAQDRLAKLQEAYCQYLLSYDSLSPEEHRRLEKEVLMEKEILEKRKGPLEGHTENDHHKF
HPLPRFEPKNGLIHGVAPRNGFRSKLKEVGQAQLKTGRRRLFAQEKEVVKEEEEDKGVLNDFHKCIYKRALGNQKSTVVEFSNKDASEIN
SEQDKENSLIKSEPRRIKIFDGGYKSNEEYVYVRGRGRGKYICEECGIRCKKPSMLKKHIRTHTDVRPYHCTYCNFSFKTKGNLTKHMKS
KAHSKKCVDLGVSVGLIDEQDTEESDEKQRFSYERSGYDLEESDGPDEDDNENEDDDEDSQAESVLSATPSVTASPQHLPSRSSLQDPVS
TDEDVRITDCFSGVHTDPMDVLPRALLTRMTVLSTAQSDYNRKTLSPGKARQRAARDENDTIPSVDTSRSPCHQMSVDYPESEEILRSSM
AGKAVAITQSPSSVRLPPAAAEHSPQTAAGMPSVASPHPDPQEQKQQITLQPTPGLPSPHTHLFSHLPLHSQQQSRTPYNMVPVGGIHVV
PAGLTYSTFVPLQAGPVQLTIPAVSVVHRTLGTHRNTVTEVSGTTNPAGVAELSSVVPCIPIGQIRVPGLQNLSTPGLQSLPSLSMETVN
IVGLANTNMAPQVHPPGLALNAVGLQVLTANPSSQSSPAPQAHIPGLQILNIALPTLIPSVSQVAVDAQGAPEMPASQSKACETQPKQTS
VASANQVSRTESPQGLPTVQRENAKKVLNPPAPAGDHARLDGLSKMDTEKAASANHVKPKPELTSIQGQPASTSQPLLKAHSEVFTKPSG

--------------------------------------------------------------

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Fusion Gene PPI Analysis for JARID2-HIVEP1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for JARID2-HIVEP1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for JARID2-HIVEP1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource