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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:JMJD1C-NEMF (FusionGDB2 ID:40974)

Fusion Gene Summary for JMJD1C-NEMF

check button Fusion gene summary
Fusion gene informationFusion gene name: JMJD1C-NEMF
Fusion gene ID: 40974
HgeneTgene
Gene symbol

JMJD1C

NEMF

Gene ID

221037

9147

Gene namejumonji domain containing 1Cnuclear export mediator factor
SynonymsKDM3C|TRIP-8|TRIP8NY-CO-1|SDCCAG1
Cytomap

10q21.3

14q21.3

Type of geneprotein-codingprotein-coding
Descriptionprobable JmjC domain-containing histone demethylation protein 2CTR-interacting protein 8thyroid hormone receptor interactor 8thyroid receptor-interacting protein 8nuclear export mediator factor NEMFantigen NY-CO-1serologically defined colon cancer antigen 1
Modification date2020031320200313
UniProtAcc

Q15652

O60524

Ensembl transtripts involved in fusion geneENST00000399251, ENST00000399262, 
ENST00000402544, ENST00000542921, 
ENST00000489372, 		ENST00000298310, 
ENST00000382135, ENST00000545773, 
ENST00000546046, ENST00000556925, 
ENST00000556672, 
Fusion gene scores* DoF score29 X 18 X 10=52206 X 8 X 4=192
# samples 319
** MAII scorelog2(31/5220*10)=-4.07370968618301
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/192*10)=-1.09310940439148
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: JMJD1C [Title/Abstract] AND NEMF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointJMJD1C(64936057)-NEMF(50256061), # samples:1
Anticipated loss of major functional domain due to fusion event.JMJD1C-NEMF seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
JMJD1C-NEMF seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
JMJD1C-NEMF seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
JMJD1C-NEMF seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across JMJD1C (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across NEMF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4HB-01AJMJD1Cchr10

64936057

-NEMFchr14

50256061

-


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Fusion Gene ORF analysis for JMJD1C-NEMF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000399251ENST00000298310JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
3UTR-3CDSENST00000399251ENST00000382135JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
3UTR-3CDSENST00000399251ENST00000545773JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
3UTR-5UTRENST00000399251ENST00000546046JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
3UTR-5UTRENST00000399251ENST00000556925JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
3UTR-intronENST00000399251ENST00000556672JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
5CDS-5UTRENST00000399262ENST00000546046JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
5CDS-5UTRENST00000399262ENST00000556925JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
5CDS-5UTRENST00000402544ENST00000546046JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
5CDS-5UTRENST00000402544ENST00000556925JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
5CDS-5UTRENST00000542921ENST00000546046JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
5CDS-5UTRENST00000542921ENST00000556925JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
5CDS-intronENST00000399262ENST00000556672JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
5CDS-intronENST00000402544ENST00000556672JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
5CDS-intronENST00000542921ENST00000556672JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
Frame-shiftENST00000402544ENST00000298310JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
Frame-shiftENST00000402544ENST00000382135JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
Frame-shiftENST00000402544ENST00000545773JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
Frame-shiftENST00000542921ENST00000298310JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
Frame-shiftENST00000542921ENST00000382135JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
Frame-shiftENST00000542921ENST00000545773JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
In-frameENST00000399262ENST00000298310JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
In-frameENST00000399262ENST00000382135JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
In-frameENST00000399262ENST00000545773JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
intron-3CDSENST00000489372ENST00000298310JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
intron-3CDSENST00000489372ENST00000382135JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
intron-3CDSENST00000489372ENST00000545773JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
intron-5UTRENST00000489372ENST00000546046JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
intron-5UTRENST00000489372ENST00000556925JMJD1Cchr10

64936057

-NEMFchr14

50256061

-
intron-intronENST00000489372ENST00000556672JMJD1Cchr10

64936057

-NEMFchr14

50256061

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000399262JMJD1Cchr1064936057-ENST00000298310NEMFchr1450256061-9511762018381532656
ENST00000399262JMJD1Cchr1064936057-ENST00000382135NEMFchr1450256061-8976762018381532656
ENST00000399262JMJD1Cchr1064936057-ENST00000545773NEMFchr1450256061-8976762018381532656

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000399262ENST00000298310JMJD1Cchr1064936057-NEMFchr1450256061-0.0001195110.99988043
ENST00000399262ENST00000382135JMJD1Cchr1064936057-NEMFchr1450256061-0.0001452320.9998548
ENST00000399262ENST00000545773JMJD1Cchr1064936057-NEMFchr1450256061-0.0001452320.9998548

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Fusion Genomic Features for JMJD1C-NEMF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for JMJD1C-NEMF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:64936057/chr14:50256061)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
JMJD1C

Q15652

NEMF

O60524

FUNCTION: Probable histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May be involved in hormone-dependent transcriptional activation, by participating in recruitment to androgen-receptor target genes (By similarity). {ECO:0000250}.FUNCTION: Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875). May indirectly play a role in nuclear export (PubMed:16103875). {ECO:0000269|PubMed:16103875, ECO:0000269|PubMed:25578875}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneJMJD1Cchr10:64936057chr14:50256061ENST00000399251-23252274_24982180477.0DomainJmjC
HgeneJMJD1Cchr10:64936057chr14:50256061ENST00000399251-23252066_20702180477.0MotifNote=LXXLL motif
HgeneJMJD1Cchr10:64936057chr14:50256061ENST00000399262-24262066_207024672541.0MotifNote=LXXLL motif
HgeneJMJD1Cchr10:64936057chr14:50256061ENST00000542921-23252066_207022852359.0MotifNote=LXXLL motif
HgeneJMJD1Cchr10:64936057chr14:50256061ENST00000399251-23251846_18712180477.0Zinc fingerC6-type
HgeneJMJD1Cchr10:64936057chr14:50256061ENST00000399262-24261846_187124672541.0Zinc fingerC6-type
HgeneJMJD1Cchr10:64936057chr14:50256061ENST00000542921-23251846_187122852359.0Zinc fingerC6-type
TgeneNEMFchr10:64936057chr14:50256061ENST0000038213529296_35999277.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST0000038213529483_51499277.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST0000038213529869_89499277.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST000005457732532869_8948571035.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneJMJD1Cchr10:64936057chr14:50256061ENST00000399262-24262274_249824672541.0DomainJmjC
HgeneJMJD1Cchr10:64936057chr14:50256061ENST00000542921-23252274_249822852359.0DomainJmjC
TgeneNEMFchr10:64936057chr14:50256061ENST000002983102633296_3598991077.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST000002983102633483_5148991077.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST000002983102633869_8948991077.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST000005457732532296_3598571035.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST000005457732532483_5148571035.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST000005460462532296_3598781056.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST000005460462532483_5148781056.0Coiled coilOntology_term=ECO:0000255
TgeneNEMFchr10:64936057chr14:50256061ENST000005460462532869_8948781056.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for JMJD1C-NEMF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>40974_40974_1_JMJD1C-NEMF_JMJD1C_chr10_64936057_ENST00000399262_NEMF_chr14_50256061_ENST00000298310_length(transcript)=9511nt_BP=7620nt
CACAAGGCTGCGAATCTGGGAGTCCAAAGGAGTGTTTGCGGGGAGGGCCCGAGGTCGCTGTGTCCGGGGCAGAGCGGCCGGTTCGTCCCG
AGTCTGCGCTCTTTCGGGTCCGCTGCTGTGTCCCGGTCCGCTCTCCTCAGCATGAGCGGCCGGTAGGAGTGAGGTTTCATCGGTTCCCTC
GCACTGGAGGAGGCAGCGGCCGCTTCGGCAGCGACAGCTATGGCGGTAGAGACGCGGGCAGAGCTGGTGGGTAAGCGGTTCCTGTGTGTG
GCGGTCGGCGACGAGGCACGTTCGGAGCGCTGGGAGAGCGGACGCGGCTGGCGAAGCTGGCGAGCGGGGGTCATCCGAGCCGTGTCACAC
AGGGACAGCCGCAATCCGGACCTGGCGGTGTATGTGGAATTTGATGATCTTGAATGGGATAAACGAGAGTGGGTTAAAGTTTATGAAGAT
TTTTCAACTTTCTTGGTGGAATACCACTTAATCTGGGCCAAAAGGAATGACCCTAGCCAGACTCAGGGATCAAAGAGCAAACAGATTCAG
TGGCCTGCATTGACTTTCAAACCTCTGGTTGAAAGAAATATACCCAGTTCAGTCACTGCAGTAGAATTCCTTGTAGATAAGCAACTGGAT
TTTTTAACTGAAGATAGTGCCTTTCAGCCCTACCAGGACGACATAGACAGCCTAAACCCAGTTCTCAGGGACAACCCGCAGCTTCATGAG
GAAGTGAAAGTCTGGGTAAAGGAACAAAAGGTTCAGGAGATTTTTATGCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATAT
AGACAAGACTCTGCCACCCAGTGGTTTACTGGCATAATTACTCATCATGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTA
CTAGAACCACAGAATGTCGATCCTTCTATGGTTCAAATGACCTTTCTAGATGATGTTGTTCACTCTTTGTTAAAAGGTGAAAATATTGGC
ATTACATCACGACGCAGGTCTCGTGCCAATCAAAACGTCAACGCTGTTCACAGCCATTATACACGTGCCCAAGCAAATAGTCCCAGACCA
GCAATGAACTCCCAAGCTGCTGTACCAAAACAGAATACACACCAGCAACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCA
GATAGCAGTATACCAGATGAAGAGAAGATGAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAATCCTAAAGGTAAAAACAAACAC
TTGATGAATAAAAGAAGGAAACCTGAGGAGGATGAAAAGAAACTAAATATGAAAAGACTTCGAACTGACAATGTTTCAGACTTTTCTGAG
AGCAGTGACTCAGAAAATTCAAATAAGAGAATAATAGATAATTCCTCAGAACAGAAGCCAGAGAATGAATTGAAAAATAAAAATACTTCA
AAAATAAATGGAGAAGAAGGAAAACCCCATAATAATGAGAAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATA
CAGGAAGATAAAAAACATGAAGAAGCAGAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAAGATATGATTATTCATTCGTCAGAACAG
TCCACAGTTTCTGATCATAATTCTAATGATTTACTTCCTCAGGAATGCAATATGGATAAAACACATACCATGGAATTGCTACCAAAGGAG
AAGTTTGTATCCAGACCACCCACACCAAAATGTGTTATTGATATTACAAATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGT
ACCTTTGGCCTTCAGACACTTCAGAAAATGGATCCTAATGTTAGTGATTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAACAGCA
AAAAAAGATTCTGACCAGAGCTGGGTCAGTGATGTAGTTAAAGTGGATCTAACCCAATCAAGTGTTACAAATGCTTCTTCAGGAAATGAT
CACTTGAACATGGAAAAAGAGAAGTATGTCTCTTACATTTCTCCTTTAAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGT
CCACCTCCAGAGACTATAAAATCTAAACTTAATACTTCAGTAGATACTCACAAGATAAAATCCAGCCCATCACCTGAAGTTGTTAAACCC
AAAATAACTCATTCTCCTGATTCTGTAAAGTCTAAGGCCACTTATGTGAACAGCCAAGCTACTGGTGAAAGAAGATTGGCAAATAAGATA
GAACATGAGCTATCAAGATGCAGTTTTCATCCAATTCCTACTCGAAGCAGTACATTAGAAACTACAAAGAGTCCTCTTATCATTGATAAA
AATGAGCATTTTACAGTTTACAGAGATCCTGCACTTATTGGGTCAGAAACAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCT
TTTCCTCTTCACTCCTCATCTCATAGAACCTGTTTAAATCCAGGTACCCATCATCCTGCCTTAACTCCTGCACCCCATTTACTAGCCGGA
TCATCTAGTCAAACTCCATTACCTACCATTAACACTCATCCTCTGACTAGTGGTCCACACCATGCTGTTCATCACCCTCATTTACTTCCC
ACTGTGTTACCTGGAGTGCCTACTGCCTCCTTACTTGGTGGCCACCCACGACTAGAGAGTGCTCATGCCAGCAGCTTGAGCCACTTAGCG
CTAGCACACCAGCAACAACAACAGTTGTTACAGCACCAGTCACCTCATCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTT
GGACTTTATCCAATTATTTGGCAGTATCCAAATGGAACACATGCATACTCAGGACTTGGTTTGCCTTCTTCTAAGTGGGTTCACCCAGAA
AATGCAGTTAATGCTGAAGCTTCATTAAGGAGGAATTCTCCCAGTCCTTGGCTACATCAGCCCACCCCTGTGACCTCAGCAGATGGTATT
GGATTACTTAGTCACATTCCTGTCAGACCTTCCAGTGCAGAGCCTCATCGGCCTCTTAAAATTACAGCCCATTCCAGTCCACCATTGACA
AAAACTTTAGTAGATCATCATAAGGAAGAATTAGAAAGAAAAGCTTTTATGGAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAAT
GACCTGGATCTAAATAGGTCACAGACTGGAAAAGATTGTCACTTACATAGGCATTTTGTGGATCCAGTATTAAATCAGTTACAGAGGCCA
CCCCAGGAGACTGGAGAGAGGTTAAACAAATACAAAGAGGAACACCGTCGAATTCTTCAAGAAAGTATTGATGTTGCTCCCTTTACAACT
AAAATCAAGGGACTTGAGGGTGAGAGAGAGAATTATTCCAGAGTGGCATCATCATCTTCCAGTCCTAAAAGCCATATCATCAAACAAGAT
ATGGATGTAGAACGCTCAGTATCAGATCTTTATAAAATGAAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATTG
TCTAATAGTGTGGTCAATGAACCACCAAGATCATACCCATCCAAAGAAGTTTCAAATATTTACGGTGATAAACAGAGTAATGCCCTTGCA
GCGGCAGCAGCTAATCCTCAAACTCTGACTTCATTTATAACATCTCTTTCAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAA
GGTTTAGTAGGCAAGATACCAGAACATCTTCCACATCAGATTGCATCTCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTCCTACC
CATTTGACAGTTTCTTCTACAAATACACTCCGCAGTATGCCTGCATTACATAGAGCACCAGTATTTCACCCACCAATCCATCACAGCCTG
GAAAGAAAGGAAGGCAGCTATAGTAGTCTTTCCCCTCCAACTTTAACTCCGGTGATGCCAGTAAATGCTGGTGGTAAAGTTCAAGAATCA
CAGAAGCCTCCAACTCTAATACCCGAACCAAAAGACTCCCAGGCAAATTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGA
CCTAATAATAACCTCAGCAAAGAGAAAACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCTGCTATGGCATCTGTCATTGTG
CGTCCATCTTCTAGTACAAAAACTGATAGTATGCCAGCAATGCAGTTAGCTTCTAAAGATCGTGTTAGTGAAAGATCTTCAGCTGGGGCA
CATAAAACAGATTGCCTCAAACTAGCAGAAGCCGGAGAAACTGGAAGAATCATTTTGCCAAATGTGAATTCAGACAGTGTTCACACAAAA
TCTGAAAAAAACTTTCAGGCTGTCTCACAGGGCAGTGTTCCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGAT
GTAATCACATCTGCTGCCGATACTACCAGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTCTTTATCAAATACCATTTTGGCCTCT
ACATCATCAGAATGTGTATCTTCAAAAAGTGTCAGTCAGCCAGTGGCTCAAAAACAAGAATGCAAGGTCAGCACCACAGCACCAGTTACA
TTAGCCAGTAGTAAGACAGGAAGTGTTGTTCAACCCAGTTCTGGGTTCTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCA
GCATTGGCTGCAGCTCAGTATAAAAGTAGTAATGCCAGTGAGACTGAACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTTCCT
CTGGATAGCACTGTAATCTGTAGTACAATTAACAAAGCAAACTCTGTAGGAAATGGGCAAGCTTCCCAGACAAGTCAACCAAACTACCAT
ACTAAACTGAAAAAGGCCTGGCTCACCAGACACTCAGAAGAAGATAAAAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAA
ATTATTAAGCCATGTTCTGTCAACTTAATAGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGTAAGATCATAGTTGATAAATAT
GTAAAAGATGATAAAGTCAACAGGAGAAAAGCCAAAAGAACTTATGAATCTGGCTCTGAAAGTGGAGACTCAGATGAAAGTGAAAGCAAG
TCAGAGCAAAGGACTAAAAGACAACCTAAGCCAACTTACAAAAAGAAGCAAAATGATTTGCAAAAGAGAAAAGGTGAAATAGAAGAAGAT
TTGAAACCCAATGGAGTTCTCAGCAGGAGTGCCAAAGAAAGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCA
GTATTGAAAGATTGGCGTAAAGTCAAGAAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCCTGCTGTGAGATAGGGCCTAAT
TTACAAAAGTGTCGAGAATGTAGACTTATTCGCAGTAAAAAAGGAGAAGAACCAGCTCACTCACCAGTATTTTGTAGATTTTACTACTTT
AGACGGTTGTCATTTAGTAAAAACGGAGTAGTTAGAATAGATGGTTTCTCTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGG
ACACATGAAAATTTTGAAGATGATGAACTAGATATAGAGACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAATTAGTA
ACATCTGAAAAAACAGCTTTGTCCTGGGTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCAGTGAGAGGAGTCCGGGAGATGTGTGAT
GCATGTGAAGCAACATTGTTTAACATTCACTGGGTCTGCCAAAAATGTGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGG
AAGAGTTCTAGAGATAAAGAACTATATGCTTGGATGAAGTGTGTGAAGGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATT
ATACCTGGTTCTGTTTTGACAGATCTTCTAGATGCCATGCACACTCTTAGGGAAAAATATGGTATTAAATCCCATTGTCATTGTACTAAC
AAACAGAATTTACAAGTTGGAAATTTTCCTACAATGAATGGTGTATCTCAAGTTTTACAGAATGTTCTTAATCACAGTAATAAAATTTCT
CTGTGCATGCCTGAGTCTCAGCAGCAAAATACTCCTCCGAAGTCTGAGAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGAT
AACAAGTTAACTCCTCCAGAATCCCAGTCACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCCAGAGAGGAAAAAAAAGAAAAC
AAAGAACTTACCCTTGAAAACCAAATTAAAGAAGAAAGAGAACAAGACAACTCTGAATCTCCAAATGGCAGAACATCACCTCTTGTGTCC
CAGAATAATGAACAAGGCTCAACCTTACGGGATTTGCTGACTACAACAGCTGGAAAGCTACGTGTGGGGTCTACAGATGCTGGCATTGCC
TTTGCCCCAGTATATTCAATGGGAGCCCCAAGTAGCAAAAGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTT
GAAAACAAAATTCCACCAAGTAAAACCTCCAAGATAAATGTAAAACCAGAGCTTAAAGAAGAGCCTGAAGAAAGCATAATATCTGCAGTG
GATGAAAATAATAAATTATACAGTGATATACCACATTCTTGGATCTGTGAGAAGCATATTTTATGGCTTAAGGATTATAAGAATAGCAGT
AATTGGAAGCTTTTCAAAGAATGTTGGAAACAAGGACAGCCTGCAGTGGTTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGGAAG
GCGGAATCAATTAGTCTTGATTTTGGAGACCACCAAGCTGATCTCCTGAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTAAGGAA
TTCTGGGATGGTTTTGAAGAAGTTTCAAAACGGCAGAAAAACAAGAGTGGAGAAACAGTTGTTTTAAAATTGAAAGACTGGCCTTCAGGA
GAAGACTTCAAGACTATGATGCCAGCAAGATACGAAGATCTTTTAAAAAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTC
AATTTGGCCTCTCATTTGCCAGGATTTTTTGTACGTCCTGATCTAGGACCCAGGTTGTGCAGTGCCTATGGTGTAGTTGCTGCTAAAGAT
CATGATATAGGAACAACAAATCTCCATATTGAAGTTTCTGATGTTGTAAATATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCATT
CTCTCAAAAGCAGGAATTCTCAAGAAATTTGAGGAAGAAGATTTGGATGACATTTTAAGGAAAAGATTGAAGGACTCAAGTGAAATACCT
GGTGCTCTGTGGCATATTTATGCTGGGAAAGATGTTGACAAGATAAGGGAATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTT
CTACCAGAACATGATCCAATACGTGACCAAAGTTGGTATGTGAACAAAAAGCTCCGTCAAAGGCTGCTTGAAGAATATGGAGTCAGAACC
TGTACTCTTATTCAGTTCCTTGGTGATGCTATTGTTTTGCCAGCGGGAGCACTTCATCAGTCTGCAGGTTCAAACAAAGAAGAAAAAGGG
AAGAAGGGGAAGAAAGGAAAAACAAAGGACGAACCTGTGAAGAAACAGCCCCAGAAACCTAGAGGTGGACAGAGGGTCTCTGACAACATT
AAGAAAGAAACTCCGTTCCTTGAGGTTATAACTCATGAGTTACAAGACTTTGCTGTAGATGATCCACATGATGACAAGGAAGAGCAAGAT
CTGGATCAACAGGGAAATGAGGAAAACCTATTTGATTCTTTGACAGGCCAGCCACATCCTGAAGATGTACTACTGTTTGCCATTCCAATA
TGTGCCCCTTACACCACCATGACAAACTACAAATATAAAGTGAAACTTACTCCTGGAGTGCAGAAAAAGGGAAAAGCTGCAAAAACAGCC
TTGAATAGTTTCATGCATTCCAAAGAAGCAACAGCAAGAGAAAAAGACTTATTCCGCAGCGTAAAGGACACAGATTTATCAAGAAACATT
CCTGGCAAAGTGAAAGTGTCTGCACCCAATCTTCTGAATGTAAAAAGGAAATAGCTGAAATGAAATTCTAAAATATTTGAGAAGAGCCAA
TTTTATAGCCTTTTGGAAGTTCAAAGATGAAAGCACCATGTATCAGGATTTCCGCATTATAAAAATGAACTAAACATTGCCTTGCTATAT
TCACCAAAAGGACTTACTTCTTGTTTTTTCCCAGTTTTATATAGAGGAAACACTGTCTATGATAGGATTTCCAAAAGTATTTGTGGACAG
TTAAATGCTAATTAATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAGTATTCATTTCATGATGTAAAG
AAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTAATATATATATTACAGGCCAAA
TGAACTAAACATTGCCTTGCTATATTCACCAAAAGGACTTAATTCTTGTTTTTTTCCCAGTTTTATATAGAGGAAACACTATGATAGGAT
TTCCTAAAGTATTTGTGGACAGTTAAATGCTAATTATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAG
TATTCATTTCATGATGTAAAGAAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTA
ATATATATATATTATAGGCCAGCTACAAGGGGTTTAAATATTTAGGATTGTGTCTTGAAAACTAAGTATTGGAGTGGATTTTCTTCTGCT
TTCATTGATACTTGTCAGAAAAAAATATTAGACCAAAATGTAAAATATAAGTAATAATTCTCATGACTCAGCTTAATCATTTCTATTCAT
TTGTAGACCTTCAGGTTTGATCTTAATTTTTTCCTTGTAATCTGATTCAGTTCTGTACCATTTTAATTTCCACCTTTAGTAATTAATTAC
CAATATAGCACGTTAGAGTATCTTAACCTATAATACCAGAAGCGCATTTTAGGCTTACCACTAAAGACTCTAACCCACTTTTCCTCTGTC
TCTTAACAGAATGGAAAATGATGTCATCATTATTTCCATTCCTTCATGAGCTATAAAACCTATTAATTAAAAAAAAACTTTTTAATTGAC
TGGACAGCACCTGCCTGTATTCAGCATGACCACTTGCTCCAGCCCCTACACTGAAGCATTAAGGTCAAAGTACTGAACAGTTGTTGGTCC
CTCCACACTTTGTTTTTCCAGCTTCGTCATAATGTGAATATTAATGTTTAAAAAAAAAAACCTTTATTATATTGTATTTACAACACTAGG

>40974_40974_1_JMJD1C-NEMF_JMJD1C_chr10_64936057_ENST00000399262_NEMF_chr14_50256061_ENST00000298310_length(amino acids)=2656AA_BP=2479
MEEAAAASAATAMAVETRAELVGKRFLCVAVGDEARSERWESGRGWRSWRAGVIRAVSHRDSRNPDLAVYVEFDDLEWDKREWVKVYEDF
STFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLRDNPQLHEE
VKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGI
TSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHL
MNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQ
EDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSST
FGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSP
PPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETTKSPLIIDKN
EHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPT
VLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPEN
AVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKND
LDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPKSHIIKQDM
DVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEG
LVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQ
KPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAH
KTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILAST
SSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPL
DSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYV
KDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSV
LKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYDDEAMSLWT
HENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERK
SSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVLNHSNKISL
CMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEEREQDNSESPNGRTSPLVSQ
NNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVD
ENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSIISNANVKEF
WDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDH
DIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVL
PEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIK
KETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKTAL

--------------------------------------------------------------
>40974_40974_2_JMJD1C-NEMF_JMJD1C_chr10_64936057_ENST00000399262_NEMF_chr14_50256061_ENST00000382135_length(transcript)=8976nt_BP=7620nt
CACAAGGCTGCGAATCTGGGAGTCCAAAGGAGTGTTTGCGGGGAGGGCCCGAGGTCGCTGTGTCCGGGGCAGAGCGGCCGGTTCGTCCCG
AGTCTGCGCTCTTTCGGGTCCGCTGCTGTGTCCCGGTCCGCTCTCCTCAGCATGAGCGGCCGGTAGGAGTGAGGTTTCATCGGTTCCCTC
GCACTGGAGGAGGCAGCGGCCGCTTCGGCAGCGACAGCTATGGCGGTAGAGACGCGGGCAGAGCTGGTGGGTAAGCGGTTCCTGTGTGTG
GCGGTCGGCGACGAGGCACGTTCGGAGCGCTGGGAGAGCGGACGCGGCTGGCGAAGCTGGCGAGCGGGGGTCATCCGAGCCGTGTCACAC
AGGGACAGCCGCAATCCGGACCTGGCGGTGTATGTGGAATTTGATGATCTTGAATGGGATAAACGAGAGTGGGTTAAAGTTTATGAAGAT
TTTTCAACTTTCTTGGTGGAATACCACTTAATCTGGGCCAAAAGGAATGACCCTAGCCAGACTCAGGGATCAAAGAGCAAACAGATTCAG
TGGCCTGCATTGACTTTCAAACCTCTGGTTGAAAGAAATATACCCAGTTCAGTCACTGCAGTAGAATTCCTTGTAGATAAGCAACTGGAT
TTTTTAACTGAAGATAGTGCCTTTCAGCCCTACCAGGACGACATAGACAGCCTAAACCCAGTTCTCAGGGACAACCCGCAGCTTCATGAG
GAAGTGAAAGTCTGGGTAAAGGAACAAAAGGTTCAGGAGATTTTTATGCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATAT
AGACAAGACTCTGCCACCCAGTGGTTTACTGGCATAATTACTCATCATGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTA
CTAGAACCACAGAATGTCGATCCTTCTATGGTTCAAATGACCTTTCTAGATGATGTTGTTCACTCTTTGTTAAAAGGTGAAAATATTGGC
ATTACATCACGACGCAGGTCTCGTGCCAATCAAAACGTCAACGCTGTTCACAGCCATTATACACGTGCCCAAGCAAATAGTCCCAGACCA
GCAATGAACTCCCAAGCTGCTGTACCAAAACAGAATACACACCAGCAACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCA
GATAGCAGTATACCAGATGAAGAGAAGATGAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAATCCTAAAGGTAAAAACAAACAC
TTGATGAATAAAAGAAGGAAACCTGAGGAGGATGAAAAGAAACTAAATATGAAAAGACTTCGAACTGACAATGTTTCAGACTTTTCTGAG
AGCAGTGACTCAGAAAATTCAAATAAGAGAATAATAGATAATTCCTCAGAACAGAAGCCAGAGAATGAATTGAAAAATAAAAATACTTCA
AAAATAAATGGAGAAGAAGGAAAACCCCATAATAATGAGAAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATA
CAGGAAGATAAAAAACATGAAGAAGCAGAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAAGATATGATTATTCATTCGTCAGAACAG
TCCACAGTTTCTGATCATAATTCTAATGATTTACTTCCTCAGGAATGCAATATGGATAAAACACATACCATGGAATTGCTACCAAAGGAG
AAGTTTGTATCCAGACCACCCACACCAAAATGTGTTATTGATATTACAAATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGT
ACCTTTGGCCTTCAGACACTTCAGAAAATGGATCCTAATGTTAGTGATTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAACAGCA
AAAAAAGATTCTGACCAGAGCTGGGTCAGTGATGTAGTTAAAGTGGATCTAACCCAATCAAGTGTTACAAATGCTTCTTCAGGAAATGAT
CACTTGAACATGGAAAAAGAGAAGTATGTCTCTTACATTTCTCCTTTAAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGT
CCACCTCCAGAGACTATAAAATCTAAACTTAATACTTCAGTAGATACTCACAAGATAAAATCCAGCCCATCACCTGAAGTTGTTAAACCC
AAAATAACTCATTCTCCTGATTCTGTAAAGTCTAAGGCCACTTATGTGAACAGCCAAGCTACTGGTGAAAGAAGATTGGCAAATAAGATA
GAACATGAGCTATCAAGATGCAGTTTTCATCCAATTCCTACTCGAAGCAGTACATTAGAAACTACAAAGAGTCCTCTTATCATTGATAAA
AATGAGCATTTTACAGTTTACAGAGATCCTGCACTTATTGGGTCAGAAACAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCT
TTTCCTCTTCACTCCTCATCTCATAGAACCTGTTTAAATCCAGGTACCCATCATCCTGCCTTAACTCCTGCACCCCATTTACTAGCCGGA
TCATCTAGTCAAACTCCATTACCTACCATTAACACTCATCCTCTGACTAGTGGTCCACACCATGCTGTTCATCACCCTCATTTACTTCCC
ACTGTGTTACCTGGAGTGCCTACTGCCTCCTTACTTGGTGGCCACCCACGACTAGAGAGTGCTCATGCCAGCAGCTTGAGCCACTTAGCG
CTAGCACACCAGCAACAACAACAGTTGTTACAGCACCAGTCACCTCATCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTT
GGACTTTATCCAATTATTTGGCAGTATCCAAATGGAACACATGCATACTCAGGACTTGGTTTGCCTTCTTCTAAGTGGGTTCACCCAGAA
AATGCAGTTAATGCTGAAGCTTCATTAAGGAGGAATTCTCCCAGTCCTTGGCTACATCAGCCCACCCCTGTGACCTCAGCAGATGGTATT
GGATTACTTAGTCACATTCCTGTCAGACCTTCCAGTGCAGAGCCTCATCGGCCTCTTAAAATTACAGCCCATTCCAGTCCACCATTGACA
AAAACTTTAGTAGATCATCATAAGGAAGAATTAGAAAGAAAAGCTTTTATGGAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAAT
GACCTGGATCTAAATAGGTCACAGACTGGAAAAGATTGTCACTTACATAGGCATTTTGTGGATCCAGTATTAAATCAGTTACAGAGGCCA
CCCCAGGAGACTGGAGAGAGGTTAAACAAATACAAAGAGGAACACCGTCGAATTCTTCAAGAAAGTATTGATGTTGCTCCCTTTACAACT
AAAATCAAGGGACTTGAGGGTGAGAGAGAGAATTATTCCAGAGTGGCATCATCATCTTCCAGTCCTAAAAGCCATATCATCAAACAAGAT
ATGGATGTAGAACGCTCAGTATCAGATCTTTATAAAATGAAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATTG
TCTAATAGTGTGGTCAATGAACCACCAAGATCATACCCATCCAAAGAAGTTTCAAATATTTACGGTGATAAACAGAGTAATGCCCTTGCA
GCGGCAGCAGCTAATCCTCAAACTCTGACTTCATTTATAACATCTCTTTCAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAA
GGTTTAGTAGGCAAGATACCAGAACATCTTCCACATCAGATTGCATCTCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTCCTACC
CATTTGACAGTTTCTTCTACAAATACACTCCGCAGTATGCCTGCATTACATAGAGCACCAGTATTTCACCCACCAATCCATCACAGCCTG
GAAAGAAAGGAAGGCAGCTATAGTAGTCTTTCCCCTCCAACTTTAACTCCGGTGATGCCAGTAAATGCTGGTGGTAAAGTTCAAGAATCA
CAGAAGCCTCCAACTCTAATACCCGAACCAAAAGACTCCCAGGCAAATTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGA
CCTAATAATAACCTCAGCAAAGAGAAAACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCTGCTATGGCATCTGTCATTGTG
CGTCCATCTTCTAGTACAAAAACTGATAGTATGCCAGCAATGCAGTTAGCTTCTAAAGATCGTGTTAGTGAAAGATCTTCAGCTGGGGCA
CATAAAACAGATTGCCTCAAACTAGCAGAAGCCGGAGAAACTGGAAGAATCATTTTGCCAAATGTGAATTCAGACAGTGTTCACACAAAA
TCTGAAAAAAACTTTCAGGCTGTCTCACAGGGCAGTGTTCCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGAT
GTAATCACATCTGCTGCCGATACTACCAGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTCTTTATCAAATACCATTTTGGCCTCT
ACATCATCAGAATGTGTATCTTCAAAAAGTGTCAGTCAGCCAGTGGCTCAAAAACAAGAATGCAAGGTCAGCACCACAGCACCAGTTACA
TTAGCCAGTAGTAAGACAGGAAGTGTTGTTCAACCCAGTTCTGGGTTCTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCA
GCATTGGCTGCAGCTCAGTATAAAAGTAGTAATGCCAGTGAGACTGAACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTTCCT
CTGGATAGCACTGTAATCTGTAGTACAATTAACAAAGCAAACTCTGTAGGAAATGGGCAAGCTTCCCAGACAAGTCAACCAAACTACCAT
ACTAAACTGAAAAAGGCCTGGCTCACCAGACACTCAGAAGAAGATAAAAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAA
ATTATTAAGCCATGTTCTGTCAACTTAATAGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGTAAGATCATAGTTGATAAATAT
GTAAAAGATGATAAAGTCAACAGGAGAAAAGCCAAAAGAACTTATGAATCTGGCTCTGAAAGTGGAGACTCAGATGAAAGTGAAAGCAAG
TCAGAGCAAAGGACTAAAAGACAACCTAAGCCAACTTACAAAAAGAAGCAAAATGATTTGCAAAAGAGAAAAGGTGAAATAGAAGAAGAT
TTGAAACCCAATGGAGTTCTCAGCAGGAGTGCCAAAGAAAGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCA
GTATTGAAAGATTGGCGTAAAGTCAAGAAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCCTGCTGTGAGATAGGGCCTAAT
TTACAAAAGTGTCGAGAATGTAGACTTATTCGCAGTAAAAAAGGAGAAGAACCAGCTCACTCACCAGTATTTTGTAGATTTTACTACTTT
AGACGGTTGTCATTTAGTAAAAACGGAGTAGTTAGAATAGATGGTTTCTCTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGG
ACACATGAAAATTTTGAAGATGATGAACTAGATATAGAGACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAATTAGTA
ACATCTGAAAAAACAGCTTTGTCCTGGGTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCAGTGAGAGGAGTCCGGGAGATGTGTGAT
GCATGTGAAGCAACATTGTTTAACATTCACTGGGTCTGCCAAAAATGTGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGG
AAGAGTTCTAGAGATAAAGAACTATATGCTTGGATGAAGTGTGTGAAGGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATT
ATACCTGGTTCTGTTTTGACAGATCTTCTAGATGCCATGCACACTCTTAGGGAAAAATATGGTATTAAATCCCATTGTCATTGTACTAAC
AAACAGAATTTACAAGTTGGAAATTTTCCTACAATGAATGGTGTATCTCAAGTTTTACAGAATGTTCTTAATCACAGTAATAAAATTTCT
CTGTGCATGCCTGAGTCTCAGCAGCAAAATACTCCTCCGAAGTCTGAGAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGAT
AACAAGTTAACTCCTCCAGAATCCCAGTCACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCCAGAGAGGAAAAAAAAGAAAAC
AAAGAACTTACCCTTGAAAACCAAATTAAAGAAGAAAGAGAACAAGACAACTCTGAATCTCCAAATGGCAGAACATCACCTCTTGTGTCC
CAGAATAATGAACAAGGCTCAACCTTACGGGATTTGCTGACTACAACAGCTGGAAAGCTACGTGTGGGGTCTACAGATGCTGGCATTGCC
TTTGCCCCAGTATATTCAATGGGAGCCCCAAGTAGCAAAAGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTT
GAAAACAAAATTCCACCAAGTAAAACCTCCAAGATAAATGTAAAACCAGAGCTTAAAGAAGAGCCTGAAGAAAGCATAATATCTGCAGTG
GATGAAAATAATAAATTATACAGTGATATACCACATTCTTGGATCTGTGAGAAGCATATTTTATGGCTTAAGGATTATAAGAATAGCAGT
AATTGGAAGCTTTTCAAAGAATGTTGGAAACAAGGACAGCCTGCAGTGGTTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGGAAG
GCGGAATCAATTAGTCTTGATTTTGGAGACCACCAAGCTGATCTCCTGAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTAAGGAA
TTCTGGGATGGTTTTGAAGAAGTTTCAAAACGGCAGAAAAACAAGAGTGGAGAAACAGTTGTTTTAAAATTGAAAGACTGGCCTTCAGGA
GAAGACTTCAAGACTATGATGCCAGCAAGATACGAAGATCTTTTAAAAAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTC
AATTTGGCCTCTCATTTGCCAGGATTTTTTGTACGTCCTGATCTAGGACCCAGGTTGTGCAGTGCCTATGGTGTAGTTGCTGCTAAAGAT
CATGATATAGGAACAACAAATCTCCATATTGAAGTTTCTGATGTTGTAAATATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCATT
CTCTCAAAAGCAGGAATTCTCAAGAAATTTGAGGAAGAAGATTTGGATGACATTTTAAGGAAAAGATTGAAGGACTCAAGTGAAATACCT
GGTGCTCTGTGGCATATTTATGCTGGGAAAGATGTTGACAAGATAAGGGAATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTT
CTACCAGAACATGATCCAATACGTGACCAAAGTTGGTATGTGAACAAAAAGCTCCGTCAAAGGCTGCTTGAAGAATATGGAGTCAGAACC
TGTACTCTTATTCAGTTCCTTGGTGATGCTATTGTTTTGCCAGCGGGAGCACTTCATCAGTCTGCAGGTTCAAACAAAGAAGAAAAAGGG
AAGAAGGGGAAGAAAGGAAAAACAAAGGACGAACCTGTGAAGAAACAGCCCCAGAAACCTAGAGGTGGACAGAGGGTCTCTGACAACATT
AAGAAAGAAACTCCGTTCCTTGAGGTTATAACTCATGAGTTACAAGACTTTGCTGTAGATGATCCACATGATGACAAGGAAGAGCAAGAT
CTGGATCAACAGGGAAATGAGGAAAACCTATTTGATTCTTTGACAGGCCAGCCACATCCTGAAGATGTACTACTGTTTGCCATTCCAATA
TGTGCCCCTTACACCACCATGACAAACTACAAATATAAAGTGAAACTTACTCCTGGAGTGCAGAAAAAGGGAAAAGCTGCAAAAACAGCC
TTGAATAGTTTCATGCATTCCAAAGAAGCAACAGCAAGAGAAAAAGACTTATTCCGCAGCGTAAAGGACACAGATTTATCAAGAAACATT
CCTGGCAAAGTGAAAGTGTCTGCACCCAATCTTCTGAATGTAAAAAGGAAATAGCTGAAATGAAATTCTAAAATATTTGAGAAGAGCCAA
TTTTATAGCCTTTTGGAAGTTCAAAGATGAAAGCACCATGTATCAGGATTTCCGCATTATAAAAATGAACTAAACATTGCCTTGCTATAT
TCACCAAAAGGACTTACTTCTTGTTTTTTCCCAGTTTTATATAGAGGAAACACTGTCTATGATAGGATTTCCAAAAGTATTTGTGGACAG
TTAAATGCTAATTAATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAGTATTCATTTCATGATGTAAAG
AAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTAATATATATATTACAGGCCAAA
TGAACTAAACATTGCCTTGCTATATTCACCAAAAGGACTTAATTCTTGTTTTTTTCCCAGTTTTATATAGAGGAAACACTATGATAGGAT
TTCCTAAAGTATTTGTGGACAGTTAAATGCTAATTATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAG
TATTCATTTCATGATGTAAAGAAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTA
ATATATATATATTATAGGCCAGCTACAAGGGGTTTAAATATTTAGGATTGTGTCTTGAAAACTAAGTATTGGAGTGGATTTTCTTCTGCT

>40974_40974_2_JMJD1C-NEMF_JMJD1C_chr10_64936057_ENST00000399262_NEMF_chr14_50256061_ENST00000382135_length(amino acids)=2656AA_BP=2479
MEEAAAASAATAMAVETRAELVGKRFLCVAVGDEARSERWESGRGWRSWRAGVIRAVSHRDSRNPDLAVYVEFDDLEWDKREWVKVYEDF
STFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLRDNPQLHEE
VKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGI
TSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHL
MNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQ
EDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSST
FGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSP
PPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETTKSPLIIDKN
EHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPT
VLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPEN
AVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKND
LDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPKSHIIKQDM
DVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEG
LVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQ
KPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAH
KTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILAST
SSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPL
DSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYV
KDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSV
LKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYDDEAMSLWT
HENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERK
SSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVLNHSNKISL
CMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEEREQDNSESPNGRTSPLVSQ
NNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVD
ENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSIISNANVKEF
WDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDH
DIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVL
PEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIK
KETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKTAL

--------------------------------------------------------------
>40974_40974_3_JMJD1C-NEMF_JMJD1C_chr10_64936057_ENST00000399262_NEMF_chr14_50256061_ENST00000545773_length(transcript)=8976nt_BP=7620nt
CACAAGGCTGCGAATCTGGGAGTCCAAAGGAGTGTTTGCGGGGAGGGCCCGAGGTCGCTGTGTCCGGGGCAGAGCGGCCGGTTCGTCCCG
AGTCTGCGCTCTTTCGGGTCCGCTGCTGTGTCCCGGTCCGCTCTCCTCAGCATGAGCGGCCGGTAGGAGTGAGGTTTCATCGGTTCCCTC
GCACTGGAGGAGGCAGCGGCCGCTTCGGCAGCGACAGCTATGGCGGTAGAGACGCGGGCAGAGCTGGTGGGTAAGCGGTTCCTGTGTGTG
GCGGTCGGCGACGAGGCACGTTCGGAGCGCTGGGAGAGCGGACGCGGCTGGCGAAGCTGGCGAGCGGGGGTCATCCGAGCCGTGTCACAC
AGGGACAGCCGCAATCCGGACCTGGCGGTGTATGTGGAATTTGATGATCTTGAATGGGATAAACGAGAGTGGGTTAAAGTTTATGAAGAT
TTTTCAACTTTCTTGGTGGAATACCACTTAATCTGGGCCAAAAGGAATGACCCTAGCCAGACTCAGGGATCAAAGAGCAAACAGATTCAG
TGGCCTGCATTGACTTTCAAACCTCTGGTTGAAAGAAATATACCCAGTTCAGTCACTGCAGTAGAATTCCTTGTAGATAAGCAACTGGAT
TTTTTAACTGAAGATAGTGCCTTTCAGCCCTACCAGGACGACATAGACAGCCTAAACCCAGTTCTCAGGGACAACCCGCAGCTTCATGAG
GAAGTGAAAGTCTGGGTAAAGGAACAAAAGGTTCAGGAGATTTTTATGCAAGGTCCTTATTCCTTAAATGGATACAGAGTGAGAGTATAT
AGACAAGACTCTGCCACCCAGTGGTTTACTGGCATAATTACTCATCATGATCTCTTCACCCGCACCATGATCGTTATGAATGATCAGGTA
CTAGAACCACAGAATGTCGATCCTTCTATGGTTCAAATGACCTTTCTAGATGATGTTGTTCACTCTTTGTTAAAAGGTGAAAATATTGGC
ATTACATCACGACGCAGGTCTCGTGCCAATCAAAACGTCAACGCTGTTCACAGCCATTATACACGTGCCCAAGCAAATAGTCCCAGACCA
GCAATGAACTCCCAAGCTGCTGTACCAAAACAGAATACACACCAGCAACAGCAACAAAGAAGTATCCGTCCAAATAAGAGGAAGGGCTCA
GATAGCAGTATACCAGATGAAGAGAAGATGAAGGAGGAAAAATATGATTATATATCACGAGGAGAAAATCCTAAAGGTAAAAACAAACAC
TTGATGAATAAAAGAAGGAAACCTGAGGAGGATGAAAAGAAACTAAATATGAAAAGACTTCGAACTGACAATGTTTCAGACTTTTCTGAG
AGCAGTGACTCAGAAAATTCAAATAAGAGAATAATAGATAATTCCTCAGAACAGAAGCCAGAGAATGAATTGAAAAATAAAAATACTTCA
AAAATAAATGGAGAAGAAGGAAAACCCCATAATAATGAGAAGGCAGGAGAAGAGACCCTAAAAAATAGCCAGCCTCCCTGGGATCAAATA
CAGGAAGATAAAAAACATGAAGAAGCAGAGAAGCGGAAGTCTGTTGACACTCAGCTTCAAGAAGATATGATTATTCATTCGTCAGAACAG
TCCACAGTTTCTGATCATAATTCTAATGATTTACTTCCTCAGGAATGCAATATGGATAAAACACATACCATGGAATTGCTACCAAAGGAG
AAGTTTGTATCCAGACCACCCACACCAAAATGTGTTATTGATATTACAAATGACACTAATTTAGAAAAGGTGGCTCAGGAAAACTCAAGT
ACCTTTGGCCTTCAGACACTTCAGAAAATGGATCCTAATGTTAGTGATTCAAAACACTCTATTGCAAATGCAAAATTCTTGGAAACAGCA
AAAAAAGATTCTGACCAGAGCTGGGTCAGTGATGTAGTTAAAGTGGATCTAACCCAATCAAGTGTTACAAATGCTTCTTCAGGAAATGAT
CACTTGAACATGGAAAAAGAGAAGTATGTCTCTTACATTTCTCCTTTAAGTGCAGTTTCTGTCATGGAAGATAAGCTGCATAAGCGAAGT
CCACCTCCAGAGACTATAAAATCTAAACTTAATACTTCAGTAGATACTCACAAGATAAAATCCAGCCCATCACCTGAAGTTGTTAAACCC
AAAATAACTCATTCTCCTGATTCTGTAAAGTCTAAGGCCACTTATGTGAACAGCCAAGCTACTGGTGAAAGAAGATTGGCAAATAAGATA
GAACATGAGCTATCAAGATGCAGTTTTCATCCAATTCCTACTCGAAGCAGTACATTAGAAACTACAAAGAGTCCTCTTATCATTGATAAA
AATGAGCATTTTACAGTTTACAGAGATCCTGCACTTATTGGGTCAGAAACAGGAGCTAATCATATTTCACCTTTCCTAAGCCAGCATCCT
TTTCCTCTTCACTCCTCATCTCATAGAACCTGTTTAAATCCAGGTACCCATCATCCTGCCTTAACTCCTGCACCCCATTTACTAGCCGGA
TCATCTAGTCAAACTCCATTACCTACCATTAACACTCATCCTCTGACTAGTGGTCCACACCATGCTGTTCATCACCCTCATTTACTTCCC
ACTGTGTTACCTGGAGTGCCTACTGCCTCCTTACTTGGTGGCCACCCACGACTAGAGAGTGCTCATGCCAGCAGCTTGAGCCACTTAGCG
CTAGCACACCAGCAACAACAACAGTTGTTACAGCACCAGTCACCTCATCTTCTTGGACAAGCCCATCCTTCTGCTTCATATAATCAGCTT
GGACTTTATCCAATTATTTGGCAGTATCCAAATGGAACACATGCATACTCAGGACTTGGTTTGCCTTCTTCTAAGTGGGTTCACCCAGAA
AATGCAGTTAATGCTGAAGCTTCATTAAGGAGGAATTCTCCCAGTCCTTGGCTACATCAGCCCACCCCTGTGACCTCAGCAGATGGTATT
GGATTACTTAGTCACATTCCTGTCAGACCTTCCAGTGCAGAGCCTCATCGGCCTCTTAAAATTACAGCCCATTCCAGTCCACCATTGACA
AAAACTTTAGTAGATCATCATAAGGAAGAATTAGAAAGAAAAGCTTTTATGGAACCATTACGGTCTGTTGCATCCACATCAGCCAAAAAT
GACCTGGATCTAAATAGGTCACAGACTGGAAAAGATTGTCACTTACATAGGCATTTTGTGGATCCAGTATTAAATCAGTTACAGAGGCCA
CCCCAGGAGACTGGAGAGAGGTTAAACAAATACAAAGAGGAACACCGTCGAATTCTTCAAGAAAGTATTGATGTTGCTCCCTTTACAACT
AAAATCAAGGGACTTGAGGGTGAGAGAGAGAATTATTCCAGAGTGGCATCATCATCTTCCAGTCCTAAAAGCCATATCATCAAACAAGAT
ATGGATGTAGAACGCTCAGTATCAGATCTTTATAAAATGAAGCACTCAGTGCCTCAGAGTTTACCCCAAAGTAACTATTTCACTACATTG
TCTAATAGTGTGGTCAATGAACCACCAAGATCATACCCATCCAAAGAAGTTTCAAATATTTACGGTGATAAACAGAGTAATGCCCTTGCA
GCGGCAGCAGCTAATCCTCAAACTCTGACTTCATTTATAACATCTCTTTCAAAGCCTCCACCTTTGATTAAACACCAACCAGAAAGTGAA
GGTTTAGTAGGCAAGATACCAGAACATCTTCCACATCAGATTGCATCTCACTCAGTAACAACCTTCAGAAATGATTGTAGGAGTCCTACC
CATTTGACAGTTTCTTCTACAAATACACTCCGCAGTATGCCTGCATTACATAGAGCACCAGTATTTCACCCACCAATCCATCACAGCCTG
GAAAGAAAGGAAGGCAGCTATAGTAGTCTTTCCCCTCCAACTTTAACTCCGGTGATGCCAGTAAATGCTGGTGGTAAAGTTCAAGAATCA
CAGAAGCCTCCAACTCTAATACCCGAACCAAAAGACTCCCAGGCAAATTTTAAGAGTTCTTCAGAACAGAGTTTGACGGAGATGTGGAGA
CCTAATAATAACCTCAGCAAAGAGAAAACTGAATGGCATGTGGAGAAAAGCAGCGGAAAGTTACAGGCTGCTATGGCATCTGTCATTGTG
CGTCCATCTTCTAGTACAAAAACTGATAGTATGCCAGCAATGCAGTTAGCTTCTAAAGATCGTGTTAGTGAAAGATCTTCAGCTGGGGCA
CATAAAACAGATTGCCTCAAACTAGCAGAAGCCGGAGAAACTGGAAGAATCATTTTGCCAAATGTGAATTCAGACAGTGTTCACACAAAA
TCTGAAAAAAACTTTCAGGCTGTCTCACAGGGCAGTGTTCCCAGTTCAGTCATGTCTGCTGTAAATACGATGTGTAATACCAAAACGGAT
GTAATCACATCTGCTGCCGATACTACCAGTGTTTCCAGCTGGGGTGGTTCAGAAGTAATTTCCTCTTTATCAAATACCATTTTGGCCTCT
ACATCATCAGAATGTGTATCTTCAAAAAGTGTCAGTCAGCCAGTGGCTCAAAAACAAGAATGCAAGGTCAGCACCACAGCACCAGTTACA
TTAGCCAGTAGTAAGACAGGAAGTGTTGTTCAACCCAGTTCTGGGTTCTCAGGCACAACTGATTTTATCCATTTAAAAAAGCACAAGGCA
GCATTGGCTGCAGCTCAGTATAAAAGTAGTAATGCCAGTGAGACTGAACCTAATGCTATAAAAAATCAGACACTTTCAGCCTCCCTTCCT
CTGGATAGCACTGTAATCTGTAGTACAATTAACAAAGCAAACTCTGTAGGAAATGGGCAAGCTTCCCAGACAAGTCAACCAAACTACCAT
ACTAAACTGAAAAAGGCCTGGCTCACCAGACACTCAGAAGAAGATAAAAATACTAATAAAATGGAAAATTCAGGGAATTCTGTATCAGAA
ATTATTAAGCCATGTTCTGTCAACTTAATAGCCTCTACATCTAGTGATATACAAAATAGTGTAGATAGTAAGATCATAGTTGATAAATAT
GTAAAAGATGATAAAGTCAACAGGAGAAAAGCCAAAAGAACTTATGAATCTGGCTCTGAAAGTGGAGACTCAGATGAAAGTGAAAGCAAG
TCAGAGCAAAGGACTAAAAGACAACCTAAGCCAACTTACAAAAAGAAGCAAAATGATTTGCAAAAGAGAAAAGGTGAAATAGAAGAAGAT
TTGAAACCCAATGGAGTTCTCAGCAGGAGTGCCAAAGAAAGAAGTAAACTGAAGTTGCAAAGCAACAGTAATACTGGCATTCCTCGTTCA
GTATTGAAAGATTGGCGTAAAGTCAAGAAGCTGAAGCAAACTGGGGAATCCTTTTTACAGGATGACTCCTGCTGTGAGATAGGGCCTAAT
TTACAAAAGTGTCGAGAATGTAGACTTATTCGCAGTAAAAAAGGAGAAGAACCAGCTCACTCACCAGTATTTTGTAGATTTTACTACTTT
AGACGGTTGTCATTTAGTAAAAACGGAGTAGTTAGAATAGATGGTTTCTCTTCTCCTGACCAATATGATGATGAAGCTATGAGTTTGTGG
ACACATGAAAATTTTGAAGATGATGAACTAGATATAGAGACTTCTAAATATATCTTGGATATAATAGGTGATAAGTTCTGTCAATTAGTA
ACATCTGAAAAAACAGCTTTGTCCTGGGTGAAAAAGGATGCCAAAATTGCCTGGAAAAGAGCAGTGAGAGGAGTCCGGGAGATGTGTGAT
GCATGTGAAGCAACATTGTTTAACATTCACTGGGTCTGCCAAAAATGTGGATTTGTGGTCTGCTTAGATTGTTACAAGGCAAAGGAAAGG
AAGAGTTCTAGAGATAAAGAACTATATGCTTGGATGAAGTGTGTGAAGGGACAGCCTCATGATCACAAACATTTAATGCCAACCCAAATT
ATACCTGGTTCTGTTTTGACAGATCTTCTAGATGCCATGCACACTCTTAGGGAAAAATATGGTATTAAATCCCATTGTCATTGTACTAAC
AAACAGAATTTACAAGTTGGAAATTTTCCTACAATGAATGGTGTATCTCAAGTTTTACAGAATGTTCTTAATCACAGTAATAAAATTTCT
CTGTGCATGCCTGAGTCTCAGCAGCAAAATACTCCTCCGAAGTCTGAGAAAAATGGTGGCAGCAGCCCAGAGAGTGATGTAGGCACAGAT
AACAAGTTAACTCCTCCAGAATCCCAGTCACCACTGCACTGGTTAGCAGATCTTGCAGAGCAAAAAGCCAGAGAGGAAAAAAAAGAAAAC
AAAGAACTTACCCTTGAAAACCAAATTAAAGAAGAAAGAGAACAAGACAACTCTGAATCTCCAAATGGCAGAACATCACCTCTTGTGTCC
CAGAATAATGAACAAGGCTCAACCTTACGGGATTTGCTGACTACAACAGCTGGAAAGCTACGTGTGGGGTCTACAGATGCTGGCATTGCC
TTTGCCCCAGTATATTCAATGGGAGCCCCAAGTAGCAAAAGTGGACGGACTATGCCTAACATTCTTGATGACATAATTGCTTCAGTTGTT
GAAAACAAAATTCCACCAAGTAAAACCTCCAAGATAAATGTAAAACCAGAGCTTAAAGAAGAGCCTGAAGAAAGCATAATATCTGCAGTG
GATGAAAATAATAAATTATACAGTGATATACCACATTCTTGGATCTGTGAGAAGCATATTTTATGGCTTAAGGATTATAAGAATAGCAGT
AATTGGAAGCTTTTCAAAGAATGTTGGAAACAAGGACAGCCTGCAGTGGTTTCTGGTGTGCATAAGAAAATGAACATTAGCCTATGGAAG
GCGGAATCAATTAGTCTTGATTTTGGAGACCACCAAGCTGATCTCCTGAACTGCAAAGATAGCATCATTTCAAATGCCAATGTTAAGGAA
TTCTGGGATGGTTTTGAAGAAGTTTCAAAACGGCAGAAAAACAAGAGTGGAGAAACAGTTGTTTTAAAATTGAAAGACTGGCCTTCAGGA
GAAGACTTCAAGACTATGATGCCAGCAAGATACGAAGATCTTTTAAAAAGTCTGCCATTGCCAGAATATTGTAATCCAGAAGGAAAATTC
AATTTGGCCTCTCATTTGCCAGGATTTTTTGTACGTCCTGATCTAGGACCCAGGTTGTGCAGTGCCTATGGTGTAGTTGCTGCTAAAGAT
CATGATATAGGAACAACAAATCTCCATATTGAAGTTTCTGATGTTGTAAATATACTAGTTTATGTTGGCATAGCAAAAGGAAATGGCATT
CTCTCAAAAGCAGGAATTCTCAAGAAATTTGAGGAAGAAGATTTGGATGACATTTTAAGGAAAAGATTGAAGGACTCAAGTGAAATACCT
GGTGCTCTGTGGCATATTTATGCTGGGAAAGATGTTGACAAGATAAGGGAATTTCTTCAAAAGATTTCAAAAGAACAAGGCCTTGAAGTT
CTACCAGAACATGATCCAATACGTGACCAAAGTTGGTATGTGAACAAAAAGCTCCGTCAAAGGCTGCTTGAAGAATATGGAGTCAGAACC
TGTACTCTTATTCAGTTCCTTGGTGATGCTATTGTTTTGCCAGCGGGAGCACTTCATCAGTCTGCAGGTTCAAACAAAGAAGAAAAAGGG
AAGAAGGGGAAGAAAGGAAAAACAAAGGACGAACCTGTGAAGAAACAGCCCCAGAAACCTAGAGGTGGACAGAGGGTCTCTGACAACATT
AAGAAAGAAACTCCGTTCCTTGAGGTTATAACTCATGAGTTACAAGACTTTGCTGTAGATGATCCACATGATGACAAGGAAGAGCAAGAT
CTGGATCAACAGGGAAATGAGGAAAACCTATTTGATTCTTTGACAGGCCAGCCACATCCTGAAGATGTACTACTGTTTGCCATTCCAATA
TGTGCCCCTTACACCACCATGACAAACTACAAATATAAAGTGAAACTTACTCCTGGAGTGCAGAAAAAGGGAAAAGCTGCAAAAACAGCC
TTGAATAGTTTCATGCATTCCAAAGAAGCAACAGCAAGAGAAAAAGACTTATTCCGCAGCGTAAAGGACACAGATTTATCAAGAAACATT
CCTGGCAAAGTGAAAGTGTCTGCACCCAATCTTCTGAATGTAAAAAGGAAATAGCTGAAATGAAATTCTAAAATATTTGAGAAGAGCCAA
TTTTATAGCCTTTTGGAAGTTCAAAGATGAAAGCACCATGTATCAGGATTTCCGCATTATAAAAATGAACTAAACATTGCCTTGCTATAT
TCACCAAAAGGACTTACTTCTTGTTTTTTCCCAGTTTTATATAGAGGAAACACTGTCTATGATAGGATTTCCAAAAGTATTTGTGGACAG
TTAAATGCTAATTAATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAGTATTCATTTCATGATGTAAAG
AAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTAATATATATATTACAGGCCAAA
TGAACTAAACATTGCCTTGCTATATTCACCAAAAGGACTTAATTCTTGTTTTTTTCCCAGTTTTATATAGAGGAAACACTATGATAGGAT
TTCCTAAAGTATTTGTGGACAGTTAAATGCTAATTATATACATCTGTAGTTATTCTACATTTTCTTGAAATTTGGGAGGTTAATACCAAG
TATTCATTTCATGATGTAAAGAAACTGAACAGTGAAGTGGCTTGATTGCTTAAACTATTGACTTGGTAAGTCTACTGTATATAACATCTA
ATATATATATATTATAGGCCAGCTACAAGGGGTTTAAATATTTAGGATTGTGTCTTGAAAACTAAGTATTGGAGTGGATTTTCTTCTGCT

>40974_40974_3_JMJD1C-NEMF_JMJD1C_chr10_64936057_ENST00000399262_NEMF_chr14_50256061_ENST00000545773_length(amino acids)=2656AA_BP=2479
MEEAAAASAATAMAVETRAELVGKRFLCVAVGDEARSERWESGRGWRSWRAGVIRAVSHRDSRNPDLAVYVEFDDLEWDKREWVKVYEDF
STFLVEYHLIWAKRNDPSQTQGSKSKQIQWPALTFKPLVERNIPSSVTAVEFLVDKQLDFLTEDSAFQPYQDDIDSLNPVLRDNPQLHEE
VKVWVKEQKVQEIFMQGPYSLNGYRVRVYRQDSATQWFTGIITHHDLFTRTMIVMNDQVLEPQNVDPSMVQMTFLDDVVHSLLKGENIGI
TSRRRSRANQNVNAVHSHYTRAQANSPRPAMNSQAAVPKQNTHQQQQQRSIRPNKRKGSDSSIPDEEKMKEEKYDYISRGENPKGKNKHL
MNKRRKPEEDEKKLNMKRLRTDNVSDFSESSDSENSNKRIIDNSSEQKPENELKNKNTSKINGEEGKPHNNEKAGEETLKNSQPPWDQIQ
EDKKHEEAEKRKSVDTQLQEDMIIHSSEQSTVSDHNSNDLLPQECNMDKTHTMELLPKEKFVSRPPTPKCVIDITNDTNLEKVAQENSST
FGLQTLQKMDPNVSDSKHSIANAKFLETAKKDSDQSWVSDVVKVDLTQSSVTNASSGNDHLNMEKEKYVSYISPLSAVSVMEDKLHKRSP
PPETIKSKLNTSVDTHKIKSSPSPEVVKPKITHSPDSVKSKATYVNSQATGERRLANKIEHELSRCSFHPIPTRSSTLETTKSPLIIDKN
EHFTVYRDPALIGSETGANHISPFLSQHPFPLHSSSHRTCLNPGTHHPALTPAPHLLAGSSSQTPLPTINTHPLTSGPHHAVHHPHLLPT
VLPGVPTASLLGGHPRLESAHASSLSHLALAHQQQQQLLQHQSPHLLGQAHPSASYNQLGLYPIIWQYPNGTHAYSGLGLPSSKWVHPEN
AVNAEASLRRNSPSPWLHQPTPVTSADGIGLLSHIPVRPSSAEPHRPLKITAHSSPPLTKTLVDHHKEELERKAFMEPLRSVASTSAKND
LDLNRSQTGKDCHLHRHFVDPVLNQLQRPPQETGERLNKYKEEHRRILQESIDVAPFTTKIKGLEGERENYSRVASSSSSPKSHIIKQDM
DVERSVSDLYKMKHSVPQSLPQSNYFTTLSNSVVNEPPRSYPSKEVSNIYGDKQSNALAAAAANPQTLTSFITSLSKPPPLIKHQPESEG
LVGKIPEHLPHQIASHSVTTFRNDCRSPTHLTVSSTNTLRSMPALHRAPVFHPPIHHSLERKEGSYSSLSPPTLTPVMPVNAGGKVQESQ
KPPTLIPEPKDSQANFKSSSEQSLTEMWRPNNNLSKEKTEWHVEKSSGKLQAAMASVIVRPSSSTKTDSMPAMQLASKDRVSERSSAGAH
KTDCLKLAEAGETGRIILPNVNSDSVHTKSEKNFQAVSQGSVPSSVMSAVNTMCNTKTDVITSAADTTSVSSWGGSEVISSLSNTILAST
SSECVSSKSVSQPVAQKQECKVSTTAPVTLASSKTGSVVQPSSGFSGTTDFIHLKKHKAALAAAQYKSSNASETEPNAIKNQTLSASLPL
DSTVICSTINKANSVGNGQASQTSQPNYHTKLKKAWLTRHSEEDKNTNKMENSGNSVSEIIKPCSVNLIASTSSDIQNSVDSKIIVDKYV
KDDKVNRRKAKRTYESGSESGDSDESESKSEQRTKRQPKPTYKKKQNDLQKRKGEIEEDLKPNGVLSRSAKERSKLKLQSNSNTGIPRSV
LKDWRKVKKLKQTGESFLQDDSCCEIGPNLQKCRECRLIRSKKGEEPAHSPVFCRFYYFRRLSFSKNGVVRIDGFSSPDQYDDEAMSLWT
HENFEDDELDIETSKYILDIIGDKFCQLVTSEKTALSWVKKDAKIAWKRAVRGVREMCDACEATLFNIHWVCQKCGFVVCLDCYKAKERK
SSRDKELYAWMKCVKGQPHDHKHLMPTQIIPGSVLTDLLDAMHTLREKYGIKSHCHCTNKQNLQVGNFPTMNGVSQVLQNVLNHSNKISL
CMPESQQQNTPPKSEKNGGSSPESDVGTDNKLTPPESQSPLHWLADLAEQKAREEKKENKELTLENQIKEEREQDNSESPNGRTSPLVSQ
NNEQGSTLRDLLTTTAGKLRVGSTDAGIAFAPVYSMGAPSSKSGRTMPNILDDIIASVVENKIPPSKTSKINVKPELKEEPEESIISAVD
ENNKLYSDIPHSWICEKHILWLKDYKNSSNWKLFKECWKQGQPAVVSGVHKKMNISLWKAESISLDFGDHQADLLNCKDSIISNANVKEF
WDGFEEVSKRQKNKSGETVVLKLKDWPSGEDFKTMMPARYEDLLKSLPLPEYCNPEGKFNLASHLPGFFVRPDLGPRLCSAYGVVAAKDH
DIGTTNLHIEVSDVVNILVYVGIAKGNGILSKAGILKKFEEEDLDDILRKRLKDSSEIPGALWHIYAGKDVDKIREFLQKISKEQGLEVL
PEHDPIRDQSWYVNKKLRQRLLEEYGVRTCTLIQFLGDAIVLPAGALHQSAGSNKEEKGKKGKKGKTKDEPVKKQPQKPRGGQRVSDNIK
KETPFLEVITHELQDFAVDDPHDDKEEQDLDQQGNEENLFDSLTGQPHPEDVLLFAIPICAPYTTMTNYKYKVKLTPGVQKKGKAAKTAL

--------------------------------------------------------------

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Fusion Gene PPI Analysis for JMJD1C-NEMF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for JMJD1C-NEMF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for JMJD1C-NEMF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource