FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:KAT6A-IKBKB (FusionGDB2 ID:41207)

Fusion Gene Summary for KAT6A-IKBKB

check button Fusion gene summary
Fusion gene informationFusion gene name: KAT6A-IKBKB
Fusion gene ID: 41207
HgeneTgene
Gene symbol

KAT6A

IKBKB

Gene ID

7994

3551

Gene namelysine acetyltransferase 6Ainhibitor of nuclear factor kappa B kinase subunit beta
SynonymsARTHS|MOZ|MRD32|MYST-3|MYST3|RUNXBP2|ZC2HC6A|ZNF220IKK-beta|IKK2|IKKB|IMD15|IMD15A|IMD15B|NFKBIKB
Cytomap

8p11.21

8p11.21

Type of geneprotein-codingprotein-coding
Descriptionhistone acetyltransferase KAT6AK(lysine) acetyltransferase 6AMOZ, YBF2/SAS3, SAS2 and TIP60 protein 3MYST histone acetyltransferase (monocytic leukemia) 3histone acetyltransferase MYST3monocytic leukemia zinc finger proteinrunt-related transcriptioninhibitor of nuclear factor kappa-B kinase subunit betaI-kappa-B kinase 2I-kappa-B-kinase betainhibitor of kappa light polypeptide gene enhancer in B-cells, kinase betanuclear factor NF-kappa-B inhibitor kinase beta
Modification date2020031320200313
UniProtAcc

Q92794

O14920

Ensembl transtripts involved in fusion geneENST00000265713, ENST00000396930, 
ENST00000406337, ENST00000485568, 
ENST00000379708, ENST00000416505, 
ENST00000518983, ENST00000519735, 
ENST00000520835, ENST00000522147, 
ENST00000522785, ENST00000520810, 
Fusion gene scores* DoF score26 X 32 X 13=1081611 X 14 X 4=616
# samples 4214
** MAII scorelog2(42/10816*10)=-4.68663391861606
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/616*10)=-2.13750352374993
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KAT6A [Title/Abstract] AND IKBKB [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKAT6A(41905896)-IKBKB(42146152), # samples:3
KAT6A(41905896)-IKBKB(42162705), # samples:3
Anticipated loss of major functional domain due to fusion event.KAT6A-IKBKB seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
KAT6A-IKBKB seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
KAT6A-IKBKB seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
KAT6A-IKBKB seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
KAT6A-IKBKB seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
KAT6A-IKBKB seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
KAT6A-IKBKB seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKAT6A

GO:0006473

protein acetylation

23431171

HgeneKAT6A

GO:0016573

histone acetylation

11742995|17925393

HgeneKAT6A

GO:0030099

myeloid cell differentiation

11742995

HgeneKAT6A

GO:0043966

histone H3 acetylation

16387653

HgeneKAT6A

GO:0045892

negative regulation of transcription, DNA-templated

11742995

HgeneKAT6A

GO:0045893

positive regulation of transcription, DNA-templated

11742995|11965546|18794358

TgeneIKBKB

GO:0006468

protein phosphorylation

15084260|20434986

TgeneIKBKB

GO:0018105

peptidyl-serine phosphorylation

21399639

TgeneIKBKB

GO:0042325

regulation of phosphorylation

26212789

TgeneIKBKB

GO:0045944

positive regulation of transcription by RNA polymerase II

23091055|23453807

TgeneIKBKB

GO:0051092

positive regulation of NF-kappaB transcription factor activity

15790681

TgeneIKBKB

GO:0071356

cellular response to tumor necrosis factor

23091055


check buttonFusion gene breakpoints across KAT6A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across IKBKB (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A06T-01AKAT6Achr8

41905896

-IKBKBchr8

42146152

+
ChimerDB4BRCATCGA-A8-A06T-01AKAT6Achr8

41905896

-IKBKBchr8

42147674

+
ChimerDB4BRCATCGA-A8-A06TKAT6Achr8

41905895

-IKBKBchr8

42146151

+
ChimerDB4BRCATCGA-AO-A03P-01AKAT6Achr8

41905896

-IKBKBchr8

42162705

+
ChiTaRS5.0N/AAA502963KAT6Achr8

41890458

+IKBKBchr8

42169467

+


Top

Fusion Gene ORF analysis for KAT6A-IKBKB

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000265713ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000265713ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000265713ENST00000379708KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000265713ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000265713ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000265713ENST00000416505KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000265713ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000265713ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000265713ENST00000518983KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000265713ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000265713ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000265713ENST00000519735KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000265713ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000265713ENST00000520835KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000265713ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000265713ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000265713ENST00000522147KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000265713ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000265713ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000265713ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000265713ENST00000522785KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000265713ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000396930ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000396930ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000396930ENST00000379708KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000396930ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000396930ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000396930ENST00000416505KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000396930ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000396930ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000396930ENST00000518983KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000396930ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000396930ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000396930ENST00000519735KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000396930ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000396930ENST00000520835KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000396930ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000396930ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000396930ENST00000522147KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000396930ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000396930ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000396930ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000396930ENST00000522785KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000396930ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000406337ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000406337ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000406337ENST00000379708KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000406337ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000406337ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000406337ENST00000416505KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000406337ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000406337ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000406337ENST00000518983KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000406337ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000406337ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000406337ENST00000519735KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000406337ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000406337ENST00000520835KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000406337ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000406337ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000406337ENST00000522147KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000406337ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000406337ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000406337ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000406337ENST00000522785KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000406337ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000485568ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000485568ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000485568ENST00000379708KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000485568ENST00000379708KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000485568ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000485568ENST00000416505KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000485568ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000485568ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000485568ENST00000518983KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000485568ENST00000518983KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000485568ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000485568ENST00000519735KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000485568ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000485568ENST00000520835KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000485568ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000485568ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000485568ENST00000522147KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000485568ENST00000522147KAT6Achr8

41905896

-IKBKBchr8

42162705

+
5CDS-intronENST00000485568ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42146152

+
5CDS-intronENST00000485568ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42147674

+
5CDS-intronENST00000485568ENST00000522785KAT6Achr8

41905895

-IKBKBchr8

42146151

+
5CDS-intronENST00000485568ENST00000522785KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000265713ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000265713ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000265713ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000265713ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000265713ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000265713ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000265713ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000265713ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000396930ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000396930ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000396930ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000396930ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000396930ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000396930ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000396930ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000396930ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000406337ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000406337ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000406337ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42146152

+
Frame-shiftENST00000406337ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000406337ENST00000520810KAT6Achr8

41905895

-IKBKBchr8

42146151

+
Frame-shiftENST00000406337ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000485568ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000485568ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000485568ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000485568ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000485568ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000485568ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42162705

+
Frame-shiftENST00000485568ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42147674

+
Frame-shiftENST00000485568ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42162705

+
In-frameENST00000265713ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42146152

+
In-frameENST00000265713ENST00000520810KAT6Achr8

41905895

-IKBKBchr8

42146151

+
In-frameENST00000396930ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42146152

+
In-frameENST00000396930ENST00000520810KAT6Achr8

41905895

-IKBKBchr8

42146151

+
In-frameENST00000406337ENST00000416505KAT6Achr8

41905896

-IKBKBchr8

42162705

+
In-frameENST00000406337ENST00000519735KAT6Achr8

41905896

-IKBKBchr8

42162705

+
In-frameENST00000406337ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42162705

+
In-frameENST00000406337ENST00000520835KAT6Achr8

41905896

-IKBKBchr8

42162705

+
In-frameENST00000485568ENST00000520810KAT6Achr8

41905896

-IKBKBchr8

42146152

+
In-frameENST00000485568ENST00000520810KAT6Achr8

41905895

-IKBKBchr8

42146151

+
intron-intronENST00000265713ENST00000379708KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000265713ENST00000416505KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000265713ENST00000518983KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000265713ENST00000519735KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000265713ENST00000520810KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000265713ENST00000520835KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000265713ENST00000522147KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000265713ENST00000522785KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000396930ENST00000379708KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000396930ENST00000416505KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000396930ENST00000518983KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000396930ENST00000519735KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000396930ENST00000520810KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000396930ENST00000520835KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000396930ENST00000522147KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000396930ENST00000522785KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000406337ENST00000379708KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000406337ENST00000416505KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000406337ENST00000518983KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000406337ENST00000519735KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000406337ENST00000520810KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000406337ENST00000520835KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000406337ENST00000522147KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000406337ENST00000522785KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000485568ENST00000379708KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000485568ENST00000416505KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000485568ENST00000518983KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000485568ENST00000519735KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000485568ENST00000520810KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000485568ENST00000520835KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000485568ENST00000522147KAT6Achr8

41890458

+IKBKBchr8

42169467

+
intron-intronENST00000485568ENST00000522785KAT6Achr8

41890458

+IKBKBchr8

42169467

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265713KAT6Achr841905896-ENST00000520810IKBKBchr842146152+380710124123177921
ENST00000396930KAT6Achr841905896-ENST00000520810IKBKBchr842146152+393911445443309921
ENST00000485568KAT6Achr841905896-ENST00000520810IKBKBchr842146152+380710124123177921
ENST00000406337KAT6Achr841905896-ENST00000520810IKBKBchr842162705+3612110011682982604
ENST00000406337KAT6Achr841905896-ENST00000416505IKBKBchr842162705+3136110011682982604
ENST00000406337KAT6Achr841905896-ENST00000519735IKBKBchr842162705+170811005001150216
ENST00000406337KAT6Achr841905896-ENST00000520835IKBKBchr842162705+3068110011682982604
ENST00000265713KAT6Achr841905895-ENST00000520810IKBKBchr842146151+380710124123177921
ENST00000396930KAT6Achr841905895-ENST00000520810IKBKBchr842146151+393911445443309921
ENST00000485568KAT6Achr841905895-ENST00000520810IKBKBchr842146151+380710124123177921

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265713ENST00000520810KAT6Achr841905896-IKBKBchr842146152+0.0014153620.9985846
ENST00000396930ENST00000520810KAT6Achr841905896-IKBKBchr842146152+0.0013823720.99861765
ENST00000485568ENST00000520810KAT6Achr841905896-IKBKBchr842146152+0.0014153620.9985846
ENST00000406337ENST00000520810KAT6Achr841905896-IKBKBchr842162705+0.007814720.9921853
ENST00000406337ENST00000416505KAT6Achr841905896-IKBKBchr842162705+0.0099499190.9900501
ENST00000406337ENST00000519735KAT6Achr841905896-IKBKBchr842162705+0.0018739250.9981261
ENST00000406337ENST00000520835KAT6Achr841905896-IKBKBchr842162705+0.0098456260.9901544
ENST00000265713ENST00000520810KAT6Achr841905895-IKBKBchr842146151+0.0014153620.9985846
ENST00000396930ENST00000520810KAT6Achr841905895-IKBKBchr842146151+0.0013823720.99861765
ENST00000485568ENST00000520810KAT6Achr841905895-IKBKBchr842146151+0.0014153620.9985846

Top

Fusion Genomic Features for KAT6A-IKBKB


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KAT6Achr841905895-IKBKBchr842146151+1.67E-060.99999833
KAT6Achr841905895-IKBKBchr842146151+1.67E-060.99999833
KAT6Achr841905895-IKBKBchr842147673+1.65E-060.99999833
KAT6Achr841905895-IKBKBchr842162704+2.74E-101
KAT6Achr841905895-IKBKBchr842146151+1.67E-060.99999833
KAT6Achr841905895-IKBKBchr842146151+1.67E-060.99999833
KAT6Achr841905895-IKBKBchr842147673+1.65E-060.99999833
KAT6Achr841905895-IKBKBchr842162704+2.74E-101

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for KAT6A-IKBKB


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr8:41905896/chr8:42146152)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KAT6A

Q92794

IKBKB

O14920

FUNCTION: Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML. {ECO:0000269|PubMed:11742995, ECO:0000269|PubMed:11965546, ECO:0000269|PubMed:12771199, ECO:0000269|PubMed:16387653, ECO:0000269|PubMed:17925393, ECO:0000269|PubMed:23431171}.FUNCTION: Serine kinase that plays an essential role in the NF-kappa-B signaling pathway which is activated by multiple stimuli such as inflammatory cytokines, bacterial or viral products, DNA damages or other cellular stresses (PubMed:30337470). Acts as part of the canonical IKK complex in the conventional pathway of NF-kappa-B activation. Phosphorylates inhibitors of NF-kappa-B on 2 critical serine residues. These modifications allow polyubiquitination of the inhibitors and subsequent degradation by the proteasome. In turn, free NF-kappa-B is translocated into the nucleus and activates the transcription of hundreds of genes involved in immune response, growth control, or protection against apoptosis. In addition to the NF-kappa-B inhibitors, phosphorylates several other components of the signaling pathway including NEMO/IKBKG, NF-kappa-B subunits RELA and NFKB1, as well as IKK-related kinases TBK1 and IKBKE (PubMed:11297557, PubMed:20410276). IKK-related kinase phosphorylations may prevent the overproduction of inflammatory mediators since they exert a negative regulation on canonical IKKs. Phosphorylates FOXO3, mediating the TNF-dependent inactivation of this pro-apoptotic transcription factor (PubMed:15084260). Also phosphorylates other substrates including NCOA3, BCL10 and IRS1 (PubMed:17213322). Within the nucleus, acts as an adapter protein for NFKBIA degradation in UV-induced NF-kappa-B activation (PubMed:11297557). Phosphorylates RIPK1 at 'Ser-25' which represses its kinase activity and consequently prevents TNF-mediated RIPK1-dependent cell death (By similarity). Phosphorylates the C-terminus of IRF5, stimulating IRF5 homodimerization and translocation into the nucleus (PubMed:25326418). {ECO:0000250|UniProtKB:O88351, ECO:0000269|PubMed:11297557, ECO:0000269|PubMed:15084260, ECO:0000269|PubMed:17213322, ECO:0000269|PubMed:19716809, ECO:0000269|PubMed:20410276, ECO:0000269|PubMed:20434986, ECO:0000269|PubMed:20797629, ECO:0000269|PubMed:21138416, ECO:0000269|PubMed:25326418, ECO:0000269|PubMed:30337470}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-21795_1712002005.0DomainH15
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-31895_1712002005.0DomainH15
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-31895_1712002005.0DomainH15
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-21795_1712002005.0DomainH15
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-31895_1712002005.0DomainH15
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-31895_1712002005.0DomainH15
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-21795_1712002005.0DomainH15
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-31895_1712002005.0DomainH15
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-31895_1712002005.0DomainH15
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171_1442002005.0RegionNote=Required for activation of RUNX1-1
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-21752_1662002005.0RegionNote=Required for nuclear localization
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181_1442002005.0RegionNote=Required for activation of RUNX1-1
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-31852_1662002005.0RegionNote=Required for nuclear localization
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181_1442002005.0RegionNote=Required for activation of RUNX1-1
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-31852_1662002005.0RegionNote=Required for nuclear localization
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171_1442002005.0RegionNote=Required for activation of RUNX1-1
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-21752_1662002005.0RegionNote=Required for nuclear localization
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181_1442002005.0RegionNote=Required for activation of RUNX1-1
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-31852_1662002005.0RegionNote=Required for nuclear localization
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181_1442002005.0RegionNote=Required for activation of RUNX1-1
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-31852_1662002005.0RegionNote=Required for nuclear localization
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171_1442002005.0RegionNote=Required for activation of RUNX1-1
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-21752_1662002005.0RegionNote=Required for nuclear localization
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181_1442002005.0RegionNote=Required for activation of RUNX1-1
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-31852_1662002005.0RegionNote=Required for nuclear localization
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181_1442002005.0RegionNote=Required for activation of RUNX1-1
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-31852_1662002005.0RegionNote=Required for nuclear localization
TgeneIKBKBchr8:41905895chr8:42146151ENST0000041650502115_3000698.0DomainProtein kinase
TgeneIKBKBchr8:41905896chr8:42146152ENST0000041650502115_3000698.0DomainProtein kinase
TgeneIKBKBchr8:41905895chr8:42146151ENST0000041650502121_290698.0Nucleotide bindingATP
TgeneIKBKBchr8:41905896chr8:42146152ENST0000041650502121_290698.0Nucleotide bindingATP
TgeneIKBKBchr8:41905895chr8:42146151ENST00000416505021458_4790698.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905895chr8:42146151ENST00000416505021737_7420698.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905895chr8:42146151ENST0000051973519458_47935257.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905895chr8:42146151ENST0000051973519737_74235257.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905895chr8:42146151ENST00000520810122458_47935757.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905895chr8:42146151ENST00000520810122737_74235757.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905895chr8:42146151ENST00000520835021458_47933755.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905895chr8:42146151ENST00000520835021737_74233755.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905896chr8:42146152ENST00000416505021458_4790698.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905896chr8:42146152ENST00000416505021737_7420698.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905896chr8:42146152ENST0000051973519458_47935257.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905896chr8:42146152ENST0000051973519737_74235257.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905896chr8:42146152ENST00000520810122458_47935757.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905896chr8:42146152ENST00000520810122737_74235757.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905896chr8:42146152ENST00000520835021458_47933755.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905896chr8:42146152ENST00000520835021737_74233755.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905896chr8:42162705ENST00000416505321458_47970698.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905896chr8:42162705ENST00000416505321737_74270698.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905896chr8:42162705ENST0000051973549458_479129257.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905896chr8:42162705ENST0000051973549737_742129257.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905896chr8:42162705ENST00000520810422458_479129757.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905896chr8:42162705ENST00000520810422737_742129757.0RegionNote=NEMO-binding
TgeneIKBKBchr8:41905896chr8:42162705ENST00000520835321458_479127755.0RegionNote=Leucine-zipper
TgeneIKBKBchr8:41905896chr8:42162705ENST00000520835321737_742127755.0RegionNote=NEMO-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171019_10262002005.0Compositional biasNote=Poly-Arg
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171069_10782002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171147_11502002005.0Compositional biasNote=Poly-Lys
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171221_12422002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171267_13022002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171411_14142002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171593_15972002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171643_17042002005.0Compositional biasNote=Gln/Pro-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171897_19772002005.0Compositional biasNote=Met-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217371_3792002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217788_8012002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217989_9952002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181019_10262002005.0Compositional biasNote=Poly-Arg
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181069_10782002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181147_11502002005.0Compositional biasNote=Poly-Lys
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181221_12422002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181267_13022002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181411_14142002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181593_15972002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181643_17042002005.0Compositional biasNote=Gln/Pro-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181897_19772002005.0Compositional biasNote=Met-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318371_3792002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318788_8012002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318989_9952002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181019_10262002005.0Compositional biasNote=Poly-Arg
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181069_10782002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181147_11502002005.0Compositional biasNote=Poly-Lys
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181221_12422002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181267_13022002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181411_14142002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181593_15972002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181643_17042002005.0Compositional biasNote=Gln/Pro-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181897_19772002005.0Compositional biasNote=Met-rich
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318371_3792002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318788_8012002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318989_9952002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171019_10262002005.0Compositional biasNote=Poly-Arg
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171069_10782002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171147_11502002005.0Compositional biasNote=Poly-Lys
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171221_12422002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171267_13022002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171411_14142002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171593_15972002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171643_17042002005.0Compositional biasNote=Gln/Pro-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171897_19772002005.0Compositional biasNote=Met-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217371_3792002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217788_8012002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217989_9952002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181019_10262002005.0Compositional biasNote=Poly-Arg
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181069_10782002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181147_11502002005.0Compositional biasNote=Poly-Lys
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181221_12422002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181267_13022002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181411_14142002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181593_15972002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181643_17042002005.0Compositional biasNote=Gln/Pro-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181897_19772002005.0Compositional biasNote=Met-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318371_3792002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318788_8012002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318989_9952002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181019_10262002005.0Compositional biasNote=Poly-Arg
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181069_10782002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181147_11502002005.0Compositional biasNote=Poly-Lys
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181221_12422002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181267_13022002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181411_14142002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181593_15972002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181643_17042002005.0Compositional biasNote=Gln/Pro-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181897_19772002005.0Compositional biasNote=Met-rich
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318371_3792002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318788_8012002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318989_9952002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171019_10262002005.0Compositional biasNote=Poly-Arg
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171069_10782002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171147_11502002005.0Compositional biasNote=Poly-Lys
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171221_12422002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171267_13022002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171411_14142002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171593_15972002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171643_17042002005.0Compositional biasNote=Gln/Pro-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171897_19772002005.0Compositional biasNote=Met-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217371_3792002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217788_8012002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217989_9952002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181019_10262002005.0Compositional biasNote=Poly-Arg
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181069_10782002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181147_11502002005.0Compositional biasNote=Poly-Lys
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181221_12422002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181267_13022002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181411_14142002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181593_15972002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181643_17042002005.0Compositional biasNote=Gln/Pro-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181897_19772002005.0Compositional biasNote=Met-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318371_3792002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318788_8012002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318989_9952002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181019_10262002005.0Compositional biasNote=Poly-Arg
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181069_10782002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181147_11502002005.0Compositional biasNote=Poly-Lys
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181221_12422002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181267_13022002005.0Compositional biasNote=Glu-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181411_14142002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181593_15972002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181643_17042002005.0Compositional biasNote=Gln/Pro-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181897_19772002005.0Compositional biasNote=Met-rich
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318371_3792002005.0Compositional biasNote=Poly-Ser
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318788_8012002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318989_9952002005.0Compositional biasNote=Poly-Glu
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217504_7782002005.0DomainMYST-type HAT
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318504_7782002005.0DomainMYST-type HAT
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318504_7782002005.0DomainMYST-type HAT
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217504_7782002005.0DomainMYST-type HAT
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318504_7782002005.0DomainMYST-type HAT
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318504_7782002005.0DomainMYST-type HAT
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217504_7782002005.0DomainMYST-type HAT
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318504_7782002005.0DomainMYST-type HAT
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318504_7782002005.0DomainMYST-type HAT
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171913_19482002005.0RegionNote=Required for activation of RUNX1-2
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217488_7782002005.0RegionNote=Catalytic
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217645_6492002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217654_6602002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181913_19482002005.0RegionNote=Required for activation of RUNX1-2
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318488_7782002005.0RegionNote=Catalytic
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318645_6492002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318654_6602002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181913_19482002005.0RegionNote=Required for activation of RUNX1-2
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318488_7782002005.0RegionNote=Catalytic
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318645_6492002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318654_6602002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171913_19482002005.0RegionNote=Required for activation of RUNX1-2
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217488_7782002005.0RegionNote=Catalytic
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217645_6492002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217654_6602002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181913_19482002005.0RegionNote=Required for activation of RUNX1-2
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318488_7782002005.0RegionNote=Catalytic
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318645_6492002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318654_6602002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181913_19482002005.0RegionNote=Required for activation of RUNX1-2
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318488_7782002005.0RegionNote=Catalytic
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318645_6492002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318654_6602002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171913_19482002005.0RegionNote=Required for activation of RUNX1-2
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217488_7782002005.0RegionNote=Catalytic
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217645_6492002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217654_6602002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181913_19482002005.0RegionNote=Required for activation of RUNX1-2
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318488_7782002005.0RegionNote=Catalytic
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318645_6492002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318654_6602002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181913_19482002005.0RegionNote=Required for activation of RUNX1-2
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318488_7782002005.0RegionNote=Catalytic
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318645_6492002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318654_6602002005.0RegionAcetyl-CoA binding
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217206_2652002005.0Zinc fingerPHD-type 1
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217259_3132002005.0Zinc fingerPHD-type 2
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217537_5622002005.0Zinc fingerC2HC MYST-type
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318206_2652002005.0Zinc fingerPHD-type 1
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318259_3132002005.0Zinc fingerPHD-type 2
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318537_5622002005.0Zinc fingerC2HC MYST-type
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318206_2652002005.0Zinc fingerPHD-type 1
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318259_3132002005.0Zinc fingerPHD-type 2
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318537_5622002005.0Zinc fingerC2HC MYST-type
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217206_2652002005.0Zinc fingerPHD-type 1
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217259_3132002005.0Zinc fingerPHD-type 2
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217537_5622002005.0Zinc fingerC2HC MYST-type
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318206_2652002005.0Zinc fingerPHD-type 1
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318259_3132002005.0Zinc fingerPHD-type 2
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318537_5622002005.0Zinc fingerC2HC MYST-type
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318206_2652002005.0Zinc fingerPHD-type 1
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318259_3132002005.0Zinc fingerPHD-type 2
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318537_5622002005.0Zinc fingerC2HC MYST-type
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217206_2652002005.0Zinc fingerPHD-type 1
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217259_3132002005.0Zinc fingerPHD-type 2
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217537_5622002005.0Zinc fingerC2HC MYST-type
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318206_2652002005.0Zinc fingerPHD-type 1
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318259_3132002005.0Zinc fingerPHD-type 2
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318537_5622002005.0Zinc fingerC2HC MYST-type
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318206_2652002005.0Zinc fingerPHD-type 1
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318259_3132002005.0Zinc fingerPHD-type 2
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318537_5622002005.0Zinc fingerC2HC MYST-type
TgeneIKBKBchr8:41905895chr8:42146151ENST000005197351915_30035257.0DomainProtein kinase
TgeneIKBKBchr8:41905895chr8:42146151ENST0000052081012215_30035757.0DomainProtein kinase
TgeneIKBKBchr8:41905895chr8:42146151ENST0000052083502115_30033755.0DomainProtein kinase
TgeneIKBKBchr8:41905896chr8:42146152ENST000005197351915_30035257.0DomainProtein kinase
TgeneIKBKBchr8:41905896chr8:42146152ENST0000052081012215_30035757.0DomainProtein kinase
TgeneIKBKBchr8:41905896chr8:42146152ENST0000052083502115_30033755.0DomainProtein kinase
TgeneIKBKBchr8:41905896chr8:42162705ENST0000041650532115_30070698.0DomainProtein kinase
TgeneIKBKBchr8:41905896chr8:42162705ENST000005197354915_300129257.0DomainProtein kinase
TgeneIKBKBchr8:41905896chr8:42162705ENST0000052081042215_300129757.0DomainProtein kinase
TgeneIKBKBchr8:41905896chr8:42162705ENST0000052083532115_300127755.0DomainProtein kinase
TgeneIKBKBchr8:41905895chr8:42146151ENST000005197351921_2935257.0Nucleotide bindingATP
TgeneIKBKBchr8:41905895chr8:42146151ENST0000052081012221_2935757.0Nucleotide bindingATP
TgeneIKBKBchr8:41905895chr8:42146151ENST0000052083502121_2933755.0Nucleotide bindingATP
TgeneIKBKBchr8:41905896chr8:42146152ENST000005197351921_2935257.0Nucleotide bindingATP
TgeneIKBKBchr8:41905896chr8:42146152ENST0000052081012221_2935757.0Nucleotide bindingATP
TgeneIKBKBchr8:41905896chr8:42146152ENST0000052083502121_2933755.0Nucleotide bindingATP
TgeneIKBKBchr8:41905896chr8:42162705ENST0000041650532121_2970698.0Nucleotide bindingATP
TgeneIKBKBchr8:41905896chr8:42162705ENST000005197354921_29129257.0Nucleotide bindingATP
TgeneIKBKBchr8:41905896chr8:42162705ENST0000052081042221_29129757.0Nucleotide bindingATP
TgeneIKBKBchr8:41905896chr8:42162705ENST0000052083532121_29127755.0Nucleotide bindingATP


Top

Fusion Gene Sequence for KAT6A-IKBKB


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>41207_41207_1_KAT6A-IKBKB_KAT6A_chr8_41905895_ENST00000265713_IKBKB_chr8_42146151_ENST00000520810_length(transcript)=3807nt_BP=1012nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGCA
TAAGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGAGTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTG
AGAAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTTGGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAA
GGAGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTTCCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTAC
TCAGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTTCACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGAT
TTTGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGA
TCGTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGA
TCCTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGAT
AAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGC
ATTATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGA
TGGACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCT
TCTTCCACATGAAAAGGATAAGGAAACAGGTGAGCAGATTGCCATCAAGCAGTGCCGGCAGGAGCTCAGCCCCCGGAACCGAGAGCGGTG
GTGCCTGGAGATCCAGATCATGAGAAGGCTGACCCACCCCAATGTGGTGGCTGCCCGAGATGTCCCTGAGGGGATGCAGAACTTGGCGCC
CAATGACCTGCCCCTGCTGGCCATGGAGTACTGCCAAGGAGGAGATCTCCGGAAGTACCTGAACCAGTTTGAGAACTGCTGTGGTCTGCG
GGAAGGTGCCATCCTCACCTTGCTGAGTGACATTGCCTCTGCGCTTAGATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCC
AGAAAACATCGTCCTGCAGCAAGGAGAACAGAGGTTAATACACAAAATTATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCT
TTGCACATCATTCGTGGGGACCCTGCAGTACCTGGCCCCAGAGCTACTGGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTT
CGGCACCCTGGCCTTTGAGTGCATCACGGGCTTCCGGCCCTTCCTCCCCAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAA
GAGTGAGGTGGACATTGTTGTTAGCGAAGACTTGAATGGAACGGTGAAGTTTTCAAGCTCTTTACCCTACCCCAATAATCTTAACAGTGT
CCTGGCTGAGCGACTGGAGAAGTGGCTGCAACTGATGCTGATGTGGCACCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGG
CTGCTTCAAGGCCCTGGATGACATCTTAAACTTAAAGCTGGTTCATATCTTGAACATGGTCACGGGCACCATCCACACCTACCCTGTGAC
AGAGGATGAGAGTCTGCAGAGCTTGAAGGCCAGAATCCAACAGGACACGGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGG
CCTGGCGTTGATCCCCGATAAGCCTGCCACTCAGTGTATTTCAGACGGCAAGTTAAATGAGGGCCACACATTGGACATGGATCTTGTTTT
TCTCTTTGACAACAGTAAAATCACCTATGAGACTCAGATCTCCCCACGGCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAA
GAGGAATCTCGCCTTCTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTGGCACAGCATCCAGACCCTGAAGGAAGATTGCAACCGGCTGCA
GCAGGGACAGCGAGCCGCCATGATGAATCTCCTCCGAAACAACAGCTGCCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCA
GCTCAAGGCCAAGTTGGATTTCTTCAAAACCAGCATCCAGATTGACCTGGAGAAGTACAGCGAGCAAACCGAGTTTGGGATCACATCAGA
TAAACTGCTGCTGGCCTGGAGGGAAATGGAGCAGGCTGTGGAGCTCTGTGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGAT
GGCTCTGCAGACCGACATTGTGGACTTACAGAGGAGCCCCATGGGCCGGAAGCAGGGGGGAACGCTGGACGACCTAGAGGAGCAAGCAAG
GGAGCTGTACAGGAGACTAAGGGAAAAACCTCGAGACCAGCGAACTGAGGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAAT
TCAGAGCTTCGAGAAGAAAGTGCGAGTGATCTATACGCAGCTCAGTAAAACTGTGGTTTGCAAGCAGAAGGCGCTGGAACTGTTGCCCAA
GGTGGAAGAGGTGGTGAGCTTAATGAATGAGGATGAGAAGACTGTTGTCCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCT
GAAGATTGCTTGTAGCAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGATAGCATGAATGCCTCTCGACTTAGCCAGCCTGGGCAGCTGAT
GTCTCAGCCCTCCACGGCCTCCAACAGCTTACCTGAGCCAGCCAAGAAGAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCT
GCTAGAAAATGCCATACAGGACACTGTGAGGGAACAAGACCAGAGTTTCACGGCCCTAGACTGGAGCTGGTTACAGACGGAAGAAGAAGA
GCACAGCTGCCTGGAGCAGGCCTCATGATGTGGGGGGACTCGACCCCCTGACATGGGGCAGCCCATAGCAGGCCTTGTGCAGTGGGGGGA
CTCGACCCCCTGACATGGGGCTGCCTGGAGCAGGCCGCGTGACGTGGGGCTGCCTGGCCGCGGCTCTCACATGGTGGTTCCTGCTGCACT
GATGGCCCAGGGGTCTCTGGTATCCAGATGGAGCTCTCGCTTCCTCAGCAGCTGTGACTTTCACCCAGGACCCAGGACGCAGCCCTCCGT
GGGCACTGCCGGCGCCTTGTCTGCACACTGGAGGTCCTCCATTACAGAGGCCCAGCGCACATCGCTGGCCCCACAAACGTTCAGGGGTAC
AGCCATGGCAGCTCCTTCCTCTGCCGTGAGAAAAGTGCTTGGAGTACGGTTTGCCACACACGTGACTGGACAGTGTCCAATTCAAATCTT
TCAGGGCAGAGTCCGAGCAGCGCTTGGTGACAGCCTGTCCTCTCCTGCTCTCCAAAGGCCCTGCTCCCTGTCCTCTCTCACTTTACAGCT
TGTGTTTCTTCTGGATTCAGCTTCTCCTAAACAGACAGTTTAATTATAGTTGCGGCCTGGCCCCATCCTCACTTCCTCTTTTTATTTCAC

>41207_41207_1_KAT6A-IKBKB_KAT6A_chr8_41905895_ENST00000265713_IKBKB_chr8_42146151_ENST00000520810_length(amino acids)=921AA_BP=188
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKDPDNPGRIALPKPRNHGK
LDNKQNVDWNKLIKRAVEGLAESGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE
SCESLSCLPPVSLLPHEKDKETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLR
KYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLE
QQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHP
RQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGK
LNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCL
SKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRK
QGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVR
LQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFT

--------------------------------------------------------------
>41207_41207_2_KAT6A-IKBKB_KAT6A_chr8_41905895_ENST00000396930_IKBKB_chr8_42146151_ENST00000520810_length(transcript)=3939nt_BP=1144nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGAT
TCTTTCTACTAATCCAGATACTTGTTGAAGTGCTGACTAGTTTCTTGGGGAAAGATGTCAAGGAAGAGTTGAAATTCCTAGACTGGTGAG
CAGAGATTGCGGAGTACAGAATAGCCATCACCCACTCTGGCATAAGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGA
GTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTGAGAAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTT
GGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAAGGAGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTT
CCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTACTCAGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTT
CACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTTTGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGA
AGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGATCGTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAAC
AATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGATCCTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGG
AAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGATAAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAA
AAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCATTATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATT
GGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGATGGACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAA
AGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCTTCTTCCACATGAAAAGGATAAGGAAACAGGTGAGCAGATTGCCATCAA
GCAGTGCCGGCAGGAGCTCAGCCCCCGGAACCGAGAGCGGTGGTGCCTGGAGATCCAGATCATGAGAAGGCTGACCCACCCCAATGTGGT
GGCTGCCCGAGATGTCCCTGAGGGGATGCAGAACTTGGCGCCCAATGACCTGCCCCTGCTGGCCATGGAGTACTGCCAAGGAGGAGATCT
CCGGAAGTACCTGAACCAGTTTGAGAACTGCTGTGGTCTGCGGGAAGGTGCCATCCTCACCTTGCTGAGTGACATTGCCTCTGCGCTTAG
ATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCCAGAAAACATCGTCCTGCAGCAAGGAGAACAGAGGTTAATACACAAAAT
TATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCTTTGCACATCATTCGTGGGGACCCTGCAGTACCTGGCCCCAGAGCTACT
GGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTTCGGCACCCTGGCCTTTGAGTGCATCACGGGCTTCCGGCCCTTCCTCCC
CAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAAGAGTGAGGTGGACATTGTTGTTAGCGAAGACTTGAATGGAACGGTGAA
GTTTTCAAGCTCTTTACCCTACCCCAATAATCTTAACAGTGTCCTGGCTGAGCGACTGGAGAAGTGGCTGCAACTGATGCTGATGTGGCA
CCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGGCTGCTTCAAGGCCCTGGATGACATCTTAAACTTAAAGCTGGTTCATAT
CTTGAACATGGTCACGGGCACCATCCACACCTACCCTGTGACAGAGGATGAGAGTCTGCAGAGCTTGAAGGCCAGAATCCAACAGGACAC
GGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGGCCTGGCGTTGATCCCCGATAAGCCTGCCACTCAGTGTATTTCAGACGG
CAAGTTAAATGAGGGCCACACATTGGACATGGATCTTGTTTTTCTCTTTGACAACAGTAAAATCACCTATGAGACTCAGATCTCCCCACG
GCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAAGAGGAATCTCGCCTTCTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTG
GCACAGCATCCAGACCCTGAAGGAAGATTGCAACCGGCTGCAGCAGGGACAGCGAGCCGCCATGATGAATCTCCTCCGAAACAACAGCTG
CCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCAGCTCAAGGCCAAGTTGGATTTCTTCAAAACCAGCATCCAGATTGACCT
GGAGAAGTACAGCGAGCAAACCGAGTTTGGGATCACATCAGATAAACTGCTGCTGGCCTGGAGGGAAATGGAGCAGGCTGTGGAGCTCTG
TGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGATGGCTCTGCAGACCGACATTGTGGACTTACAGAGGAGCCCCATGGGCCG
GAAGCAGGGGGGAACGCTGGACGACCTAGAGGAGCAAGCAAGGGAGCTGTACAGGAGACTAAGGGAAAAACCTCGAGACCAGCGAACTGA
GGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAATTCAGAGCTTCGAGAAGAAAGTGCGAGTGATCTATACGCAGCTCAGTAA
AACTGTGGTTTGCAAGCAGAAGGCGCTGGAACTGTTGCCCAAGGTGGAAGAGGTGGTGAGCTTAATGAATGAGGATGAGAAGACTGTTGT
CCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCTGAAGATTGCTTGTAGCAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGA
TAGCATGAATGCCTCTCGACTTAGCCAGCCTGGGCAGCTGATGTCTCAGCCCTCCACGGCCTCCAACAGCTTACCTGAGCCAGCCAAGAA
GAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCTGCTAGAAAATGCCATACAGGACACTGTGAGGGAACAAGACCAGAGTTT
CACGGCCCTAGACTGGAGCTGGTTACAGACGGAAGAAGAAGAGCACAGCTGCCTGGAGCAGGCCTCATGATGTGGGGGGACTCGACCCCC
TGACATGGGGCAGCCCATAGCAGGCCTTGTGCAGTGGGGGGACTCGACCCCCTGACATGGGGCTGCCTGGAGCAGGCCGCGTGACGTGGG
GCTGCCTGGCCGCGGCTCTCACATGGTGGTTCCTGCTGCACTGATGGCCCAGGGGTCTCTGGTATCCAGATGGAGCTCTCGCTTCCTCAG
CAGCTGTGACTTTCACCCAGGACCCAGGACGCAGCCCTCCGTGGGCACTGCCGGCGCCTTGTCTGCACACTGGAGGTCCTCCATTACAGA
GGCCCAGCGCACATCGCTGGCCCCACAAACGTTCAGGGGTACAGCCATGGCAGCTCCTTCCTCTGCCGTGAGAAAAGTGCTTGGAGTACG
GTTTGCCACACACGTGACTGGACAGTGTCCAATTCAAATCTTTCAGGGCAGAGTCCGAGCAGCGCTTGGTGACAGCCTGTCCTCTCCTGC
TCTCCAAAGGCCCTGCTCCCTGTCCTCTCTCACTTTACAGCTTGTGTTTCTTCTGGATTCAGCTTCTCCTAAACAGACAGTTTAATTATA

>41207_41207_2_KAT6A-IKBKB_KAT6A_chr8_41905895_ENST00000396930_IKBKB_chr8_42146151_ENST00000520810_length(amino acids)=921AA_BP=188
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKDPDNPGRIALPKPRNHGK
LDNKQNVDWNKLIKRAVEGLAESGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE
SCESLSCLPPVSLLPHEKDKETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLR
KYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLE
QQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHP
RQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGK
LNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCL
SKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRK
QGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVR
LQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFT

--------------------------------------------------------------
>41207_41207_3_KAT6A-IKBKB_KAT6A_chr8_41905895_ENST00000485568_IKBKB_chr8_42146151_ENST00000520810_length(transcript)=3807nt_BP=1012nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGCA
TAAGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGAGTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTG
AGAAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTTGGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAA
GGAGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTTCCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTAC
TCAGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTTCACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGAT
TTTGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGA
TCGTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGA
TCCTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGAT
AAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGC
ATTATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGA
TGGACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCT
TCTTCCACATGAAAAGGATAAGGAAACAGGTGAGCAGATTGCCATCAAGCAGTGCCGGCAGGAGCTCAGCCCCCGGAACCGAGAGCGGTG
GTGCCTGGAGATCCAGATCATGAGAAGGCTGACCCACCCCAATGTGGTGGCTGCCCGAGATGTCCCTGAGGGGATGCAGAACTTGGCGCC
CAATGACCTGCCCCTGCTGGCCATGGAGTACTGCCAAGGAGGAGATCTCCGGAAGTACCTGAACCAGTTTGAGAACTGCTGTGGTCTGCG
GGAAGGTGCCATCCTCACCTTGCTGAGTGACATTGCCTCTGCGCTTAGATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCC
AGAAAACATCGTCCTGCAGCAAGGAGAACAGAGGTTAATACACAAAATTATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCT
TTGCACATCATTCGTGGGGACCCTGCAGTACCTGGCCCCAGAGCTACTGGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTT
CGGCACCCTGGCCTTTGAGTGCATCACGGGCTTCCGGCCCTTCCTCCCCAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAA
GAGTGAGGTGGACATTGTTGTTAGCGAAGACTTGAATGGAACGGTGAAGTTTTCAAGCTCTTTACCCTACCCCAATAATCTTAACAGTGT
CCTGGCTGAGCGACTGGAGAAGTGGCTGCAACTGATGCTGATGTGGCACCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGG
CTGCTTCAAGGCCCTGGATGACATCTTAAACTTAAAGCTGGTTCATATCTTGAACATGGTCACGGGCACCATCCACACCTACCCTGTGAC
AGAGGATGAGAGTCTGCAGAGCTTGAAGGCCAGAATCCAACAGGACACGGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGG
CCTGGCGTTGATCCCCGATAAGCCTGCCACTCAGTGTATTTCAGACGGCAAGTTAAATGAGGGCCACACATTGGACATGGATCTTGTTTT
TCTCTTTGACAACAGTAAAATCACCTATGAGACTCAGATCTCCCCACGGCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAA
GAGGAATCTCGCCTTCTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTGGCACAGCATCCAGACCCTGAAGGAAGATTGCAACCGGCTGCA
GCAGGGACAGCGAGCCGCCATGATGAATCTCCTCCGAAACAACAGCTGCCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCA
GCTCAAGGCCAAGTTGGATTTCTTCAAAACCAGCATCCAGATTGACCTGGAGAAGTACAGCGAGCAAACCGAGTTTGGGATCACATCAGA
TAAACTGCTGCTGGCCTGGAGGGAAATGGAGCAGGCTGTGGAGCTCTGTGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGAT
GGCTCTGCAGACCGACATTGTGGACTTACAGAGGAGCCCCATGGGCCGGAAGCAGGGGGGAACGCTGGACGACCTAGAGGAGCAAGCAAG
GGAGCTGTACAGGAGACTAAGGGAAAAACCTCGAGACCAGCGAACTGAGGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAAT
TCAGAGCTTCGAGAAGAAAGTGCGAGTGATCTATACGCAGCTCAGTAAAACTGTGGTTTGCAAGCAGAAGGCGCTGGAACTGTTGCCCAA
GGTGGAAGAGGTGGTGAGCTTAATGAATGAGGATGAGAAGACTGTTGTCCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCT
GAAGATTGCTTGTAGCAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGATAGCATGAATGCCTCTCGACTTAGCCAGCCTGGGCAGCTGAT
GTCTCAGCCCTCCACGGCCTCCAACAGCTTACCTGAGCCAGCCAAGAAGAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCT
GCTAGAAAATGCCATACAGGACACTGTGAGGGAACAAGACCAGAGTTTCACGGCCCTAGACTGGAGCTGGTTACAGACGGAAGAAGAAGA
GCACAGCTGCCTGGAGCAGGCCTCATGATGTGGGGGGACTCGACCCCCTGACATGGGGCAGCCCATAGCAGGCCTTGTGCAGTGGGGGGA
CTCGACCCCCTGACATGGGGCTGCCTGGAGCAGGCCGCGTGACGTGGGGCTGCCTGGCCGCGGCTCTCACATGGTGGTTCCTGCTGCACT
GATGGCCCAGGGGTCTCTGGTATCCAGATGGAGCTCTCGCTTCCTCAGCAGCTGTGACTTTCACCCAGGACCCAGGACGCAGCCCTCCGT
GGGCACTGCCGGCGCCTTGTCTGCACACTGGAGGTCCTCCATTACAGAGGCCCAGCGCACATCGCTGGCCCCACAAACGTTCAGGGGTAC
AGCCATGGCAGCTCCTTCCTCTGCCGTGAGAAAAGTGCTTGGAGTACGGTTTGCCACACACGTGACTGGACAGTGTCCAATTCAAATCTT
TCAGGGCAGAGTCCGAGCAGCGCTTGGTGACAGCCTGTCCTCTCCTGCTCTCCAAAGGCCCTGCTCCCTGTCCTCTCTCACTTTACAGCT
TGTGTTTCTTCTGGATTCAGCTTCTCCTAAACAGACAGTTTAATTATAGTTGCGGCCTGGCCCCATCCTCACTTCCTCTTTTTATTTCAC

>41207_41207_3_KAT6A-IKBKB_KAT6A_chr8_41905895_ENST00000485568_IKBKB_chr8_42146151_ENST00000520810_length(amino acids)=921AA_BP=188
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKDPDNPGRIALPKPRNHGK
LDNKQNVDWNKLIKRAVEGLAESGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE
SCESLSCLPPVSLLPHEKDKETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLR
KYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLE
QQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHP
RQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGK
LNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCL
SKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRK
QGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVR
LQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFT

--------------------------------------------------------------
>41207_41207_4_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000265713_IKBKB_chr8_42146152_ENST00000520810_length(transcript)=3807nt_BP=1012nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGCA
TAAGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGAGTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTG
AGAAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTTGGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAA
GGAGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTTCCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTAC
TCAGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTTCACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGAT
TTTGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGA
TCGTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGA
TCCTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGAT
AAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGC
ATTATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGA
TGGACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCT
TCTTCCACATGAAAAGGATAAGGAAACAGGTGAGCAGATTGCCATCAAGCAGTGCCGGCAGGAGCTCAGCCCCCGGAACCGAGAGCGGTG
GTGCCTGGAGATCCAGATCATGAGAAGGCTGACCCACCCCAATGTGGTGGCTGCCCGAGATGTCCCTGAGGGGATGCAGAACTTGGCGCC
CAATGACCTGCCCCTGCTGGCCATGGAGTACTGCCAAGGAGGAGATCTCCGGAAGTACCTGAACCAGTTTGAGAACTGCTGTGGTCTGCG
GGAAGGTGCCATCCTCACCTTGCTGAGTGACATTGCCTCTGCGCTTAGATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCC
AGAAAACATCGTCCTGCAGCAAGGAGAACAGAGGTTAATACACAAAATTATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCT
TTGCACATCATTCGTGGGGACCCTGCAGTACCTGGCCCCAGAGCTACTGGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTT
CGGCACCCTGGCCTTTGAGTGCATCACGGGCTTCCGGCCCTTCCTCCCCAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAA
GAGTGAGGTGGACATTGTTGTTAGCGAAGACTTGAATGGAACGGTGAAGTTTTCAAGCTCTTTACCCTACCCCAATAATCTTAACAGTGT
CCTGGCTGAGCGACTGGAGAAGTGGCTGCAACTGATGCTGATGTGGCACCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGG
CTGCTTCAAGGCCCTGGATGACATCTTAAACTTAAAGCTGGTTCATATCTTGAACATGGTCACGGGCACCATCCACACCTACCCTGTGAC
AGAGGATGAGAGTCTGCAGAGCTTGAAGGCCAGAATCCAACAGGACACGGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGG
CCTGGCGTTGATCCCCGATAAGCCTGCCACTCAGTGTATTTCAGACGGCAAGTTAAATGAGGGCCACACATTGGACATGGATCTTGTTTT
TCTCTTTGACAACAGTAAAATCACCTATGAGACTCAGATCTCCCCACGGCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAA
GAGGAATCTCGCCTTCTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTGGCACAGCATCCAGACCCTGAAGGAAGATTGCAACCGGCTGCA
GCAGGGACAGCGAGCCGCCATGATGAATCTCCTCCGAAACAACAGCTGCCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCA
GCTCAAGGCCAAGTTGGATTTCTTCAAAACCAGCATCCAGATTGACCTGGAGAAGTACAGCGAGCAAACCGAGTTTGGGATCACATCAGA
TAAACTGCTGCTGGCCTGGAGGGAAATGGAGCAGGCTGTGGAGCTCTGTGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGAT
GGCTCTGCAGACCGACATTGTGGACTTACAGAGGAGCCCCATGGGCCGGAAGCAGGGGGGAACGCTGGACGACCTAGAGGAGCAAGCAAG
GGAGCTGTACAGGAGACTAAGGGAAAAACCTCGAGACCAGCGAACTGAGGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAAT
TCAGAGCTTCGAGAAGAAAGTGCGAGTGATCTATACGCAGCTCAGTAAAACTGTGGTTTGCAAGCAGAAGGCGCTGGAACTGTTGCCCAA
GGTGGAAGAGGTGGTGAGCTTAATGAATGAGGATGAGAAGACTGTTGTCCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCT
GAAGATTGCTTGTAGCAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGATAGCATGAATGCCTCTCGACTTAGCCAGCCTGGGCAGCTGAT
GTCTCAGCCCTCCACGGCCTCCAACAGCTTACCTGAGCCAGCCAAGAAGAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCT
GCTAGAAAATGCCATACAGGACACTGTGAGGGAACAAGACCAGAGTTTCACGGCCCTAGACTGGAGCTGGTTACAGACGGAAGAAGAAGA
GCACAGCTGCCTGGAGCAGGCCTCATGATGTGGGGGGACTCGACCCCCTGACATGGGGCAGCCCATAGCAGGCCTTGTGCAGTGGGGGGA
CTCGACCCCCTGACATGGGGCTGCCTGGAGCAGGCCGCGTGACGTGGGGCTGCCTGGCCGCGGCTCTCACATGGTGGTTCCTGCTGCACT
GATGGCCCAGGGGTCTCTGGTATCCAGATGGAGCTCTCGCTTCCTCAGCAGCTGTGACTTTCACCCAGGACCCAGGACGCAGCCCTCCGT
GGGCACTGCCGGCGCCTTGTCTGCACACTGGAGGTCCTCCATTACAGAGGCCCAGCGCACATCGCTGGCCCCACAAACGTTCAGGGGTAC
AGCCATGGCAGCTCCTTCCTCTGCCGTGAGAAAAGTGCTTGGAGTACGGTTTGCCACACACGTGACTGGACAGTGTCCAATTCAAATCTT
TCAGGGCAGAGTCCGAGCAGCGCTTGGTGACAGCCTGTCCTCTCCTGCTCTCCAAAGGCCCTGCTCCCTGTCCTCTCTCACTTTACAGCT
TGTGTTTCTTCTGGATTCAGCTTCTCCTAAACAGACAGTTTAATTATAGTTGCGGCCTGGCCCCATCCTCACTTCCTCTTTTTATTTCAC

>41207_41207_4_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000265713_IKBKB_chr8_42146152_ENST00000520810_length(amino acids)=921AA_BP=188
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKDPDNPGRIALPKPRNHGK
LDNKQNVDWNKLIKRAVEGLAESGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE
SCESLSCLPPVSLLPHEKDKETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLR
KYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLE
QQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHP
RQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGK
LNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCL
SKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRK
QGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVR
LQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFT

--------------------------------------------------------------
>41207_41207_5_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000396930_IKBKB_chr8_42146152_ENST00000520810_length(transcript)=3939nt_BP=1144nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGAT
TCTTTCTACTAATCCAGATACTTGTTGAAGTGCTGACTAGTTTCTTGGGGAAAGATGTCAAGGAAGAGTTGAAATTCCTAGACTGGTGAG
CAGAGATTGCGGAGTACAGAATAGCCATCACCCACTCTGGCATAAGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGA
GTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTGAGAAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTT
GGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAAGGAGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTT
CCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTACTCAGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTT
CACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTTTGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGA
AGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGATCGTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAAC
AATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGATCCTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGG
AAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGATAAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAA
AAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCATTATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATT
GGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGATGGACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAA
AGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCTTCTTCCACATGAAAAGGATAAGGAAACAGGTGAGCAGATTGCCATCAA
GCAGTGCCGGCAGGAGCTCAGCCCCCGGAACCGAGAGCGGTGGTGCCTGGAGATCCAGATCATGAGAAGGCTGACCCACCCCAATGTGGT
GGCTGCCCGAGATGTCCCTGAGGGGATGCAGAACTTGGCGCCCAATGACCTGCCCCTGCTGGCCATGGAGTACTGCCAAGGAGGAGATCT
CCGGAAGTACCTGAACCAGTTTGAGAACTGCTGTGGTCTGCGGGAAGGTGCCATCCTCACCTTGCTGAGTGACATTGCCTCTGCGCTTAG
ATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCCAGAAAACATCGTCCTGCAGCAAGGAGAACAGAGGTTAATACACAAAAT
TATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCTTTGCACATCATTCGTGGGGACCCTGCAGTACCTGGCCCCAGAGCTACT
GGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTTCGGCACCCTGGCCTTTGAGTGCATCACGGGCTTCCGGCCCTTCCTCCC
CAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAAGAGTGAGGTGGACATTGTTGTTAGCGAAGACTTGAATGGAACGGTGAA
GTTTTCAAGCTCTTTACCCTACCCCAATAATCTTAACAGTGTCCTGGCTGAGCGACTGGAGAAGTGGCTGCAACTGATGCTGATGTGGCA
CCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGGCTGCTTCAAGGCCCTGGATGACATCTTAAACTTAAAGCTGGTTCATAT
CTTGAACATGGTCACGGGCACCATCCACACCTACCCTGTGACAGAGGATGAGAGTCTGCAGAGCTTGAAGGCCAGAATCCAACAGGACAC
GGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGGCCTGGCGTTGATCCCCGATAAGCCTGCCACTCAGTGTATTTCAGACGG
CAAGTTAAATGAGGGCCACACATTGGACATGGATCTTGTTTTTCTCTTTGACAACAGTAAAATCACCTATGAGACTCAGATCTCCCCACG
GCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAAGAGGAATCTCGCCTTCTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTG
GCACAGCATCCAGACCCTGAAGGAAGATTGCAACCGGCTGCAGCAGGGACAGCGAGCCGCCATGATGAATCTCCTCCGAAACAACAGCTG
CCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCAGCTCAAGGCCAAGTTGGATTTCTTCAAAACCAGCATCCAGATTGACCT
GGAGAAGTACAGCGAGCAAACCGAGTTTGGGATCACATCAGATAAACTGCTGCTGGCCTGGAGGGAAATGGAGCAGGCTGTGGAGCTCTG
TGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGATGGCTCTGCAGACCGACATTGTGGACTTACAGAGGAGCCCCATGGGCCG
GAAGCAGGGGGGAACGCTGGACGACCTAGAGGAGCAAGCAAGGGAGCTGTACAGGAGACTAAGGGAAAAACCTCGAGACCAGCGAACTGA
GGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAATTCAGAGCTTCGAGAAGAAAGTGCGAGTGATCTATACGCAGCTCAGTAA
AACTGTGGTTTGCAAGCAGAAGGCGCTGGAACTGTTGCCCAAGGTGGAAGAGGTGGTGAGCTTAATGAATGAGGATGAGAAGACTGTTGT
CCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCTGAAGATTGCTTGTAGCAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGA
TAGCATGAATGCCTCTCGACTTAGCCAGCCTGGGCAGCTGATGTCTCAGCCCTCCACGGCCTCCAACAGCTTACCTGAGCCAGCCAAGAA
GAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCTGCTAGAAAATGCCATACAGGACACTGTGAGGGAACAAGACCAGAGTTT
CACGGCCCTAGACTGGAGCTGGTTACAGACGGAAGAAGAAGAGCACAGCTGCCTGGAGCAGGCCTCATGATGTGGGGGGACTCGACCCCC
TGACATGGGGCAGCCCATAGCAGGCCTTGTGCAGTGGGGGGACTCGACCCCCTGACATGGGGCTGCCTGGAGCAGGCCGCGTGACGTGGG
GCTGCCTGGCCGCGGCTCTCACATGGTGGTTCCTGCTGCACTGATGGCCCAGGGGTCTCTGGTATCCAGATGGAGCTCTCGCTTCCTCAG
CAGCTGTGACTTTCACCCAGGACCCAGGACGCAGCCCTCCGTGGGCACTGCCGGCGCCTTGTCTGCACACTGGAGGTCCTCCATTACAGA
GGCCCAGCGCACATCGCTGGCCCCACAAACGTTCAGGGGTACAGCCATGGCAGCTCCTTCCTCTGCCGTGAGAAAAGTGCTTGGAGTACG
GTTTGCCACACACGTGACTGGACAGTGTCCAATTCAAATCTTTCAGGGCAGAGTCCGAGCAGCGCTTGGTGACAGCCTGTCCTCTCCTGC
TCTCCAAAGGCCCTGCTCCCTGTCCTCTCTCACTTTACAGCTTGTGTTTCTTCTGGATTCAGCTTCTCCTAAACAGACAGTTTAATTATA

>41207_41207_5_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000396930_IKBKB_chr8_42146152_ENST00000520810_length(amino acids)=921AA_BP=188
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKDPDNPGRIALPKPRNHGK
LDNKQNVDWNKLIKRAVEGLAESGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE
SCESLSCLPPVSLLPHEKDKETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLR
KYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLE
QQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHP
RQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGK
LNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCL
SKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRK
QGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVR
LQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFT

--------------------------------------------------------------
>41207_41207_6_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000406337_IKBKB_chr8_42162705_ENST00000416505_length(transcript)=3136nt_BP=1100nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGAT
TCTTTCTACTAATCCAGATACTTGTTGAAGTGCTGACTAGTTTCTTGGGGAAAGATGTCAAGGAAGAGTTGAAATTCCTAGACTGGCATA
AGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGAGTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTGAG
AAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTTGGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAAGG
AGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTTCCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTACTC
AGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTTCACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTT
TGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGATC
GTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGATC
CTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGATAA
AGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCAT
TATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGATG
GACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCTTC
TTCCACATGAAAAGGATAAGCCTCTGCGCTTAGATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCCAGAAAACATCGTCCT
GCAGCAAGGAGAACAGAGGTTAATACACAAAATTATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCTTTGCACATCATTCGT
GGGGACCCTGCAGTACCTGGCCCCAGAGCTACTGGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTTCGGCACCCTGGCCTT
TGAGTGCATCACGGGCTTCCGGCCCTTCCTCCCCAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAAGAGTGAGGTGGACAT
TGTTGTTAGCGAAGACTTGAATGGAACGGTGAAGTTTTCAAGCTCTTTACCCTACCCCAATAATCTTAACAGTGTCCTGGCTGAGCGACT
GGAGAAGTGGCTGCAACTGATGCTGATGTGGCACCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGGCTGCTTCAAGGCCCT
GGATGACATCTTAAACTTAAAGCTGGTTCATATCTTGAACATGGTCACGGGCACCATCCACACCTACCCTGTGACAGAGGATGAGAGTCT
GCAGAGCTTGAAGGCCAGAATCCAACAGGACACGGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGGCCTGGCGTTGATCCC
CGATAAGCCTGCCACTCAGTGTATTTCAGACGGCAAGTTAAATGAGGGCCACACATTGGACATGGATCTTGTTTTTCTCTTTGACAACAG
TAAAATCACCTATGAGACTCAGATCTCCCCACGGCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAAGAGGAATCTCGCCTT
CTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTGGCACAGCATCCAGACCCTGAAGGAAGATTGCAACCGGCTGCAGCAGGGACAGCGAGC
CGCCATGATGAATCTCCTCCGAAACAACAGCTGCCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCAGCTCAAGGCCAAGTT
GGATTTCTTCAAAACCAGCATCCAGATTGACCTGGAGAAGTACAGCGAGCAAACCGAGTTTGGGATCACATCAGATAAACTGCTGCTGGC
CTGGAGGGAAATGGAGCAGGCTGTGGAGCTCTGTGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGATGGCTCTGCAGACCGA
CATTGTGGACTTACAGAGGAGCCCCATGGGCCGGAAGCAGGGGGGAACGCTGGACGACCTAGAGGAGCAAGCAAGGGAGCTGTACAGGAG
ACTAAGGGAAAAACCTCGAGACCAGCGAACTGAGGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAATTCAGAGCTTCGAGAA
GAAAGTGCGAGTGATCTATACGCAGCTCAGTAAAACTGTGGTTTGCAAGCAGAAGGCGCTGGAACTGTTGCCCAAGGTGGAAGAGGTGGT
GAGCTTAATGAATGAGGATGAGAAGACTGTTGTCCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCTGAAGATTGCTTGTAG
CAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGATAGCATGAATGCCTCTCGACTTAGCCAGCCTGGGCAGCTGATGTCTCAGCCCTCCAC
GGCCTCCAACAGCTTACCTGAGCCAGCCAAGAAGAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCTGCTAGAAAATGCCAT
ACAGGACACTGTGAGGGAACAAGACCAGAGTTTCACGGCCCTAGACTGGAGCTGGTTACAGACGGAAGAAGAAGAGCACAGCTGCCTGGA
GCAGGCCTCATGATGTGGGGGGACTCGACCCCCTGACATGGGGCAGCCCATAGCAGGCCTTGTGCAGTGGGGGGACTCGACCCCCTGACA

>41207_41207_6_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000406337_IKBKB_chr8_42162705_ENST00000416505_length(amino acids)=604AA_BP=
MQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVD
IVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDES
LQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLA
FFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLL
AWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFE
KKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPS

--------------------------------------------------------------
>41207_41207_7_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000406337_IKBKB_chr8_42162705_ENST00000519735_length(transcript)=1708nt_BP=1100nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGAT
TCTTTCTACTAATCCAGATACTTGTTGAAGTGCTGACTAGTTTCTTGGGGAAAGATGTCAAGGAAGAGTTGAAATTCCTAGACTGGCATA
AGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGAGTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTGAG
AAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTTGGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAAGG
AGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTTCCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTACTC
AGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTTCACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTT
TGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGATC
GTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGATC
CTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGATAA
AGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCAT
TATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGATG
GACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCTTC
TTCCACATGAAAAGGATAAGCCTCTGCGCTTAGATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCCAGAAAACATCGTCCT
GCAGCAAGGAGAACAGAGGTTAATACACAAAATTATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCTTTGCACATCATTCGT
GGGGACCCTGCAGTACCTGGCCCCAGAGCTACTGGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTTCGGCACCCTGGCCTT
TGAGTGCATCACGGGCTTCCGGCCCTTCCTCCCCAACTGGCAGCCCGTGCAGTGCGTAAGAATGTGGCCGGGTACAGTGGCTCACTCCTG
TAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCAGTTGAGGCCAGCAGTTCCAGACCAGCCTGGCCAACATGGCAAAACCCTGTCT
CTACTAAAAACCCTAGCCAGGTGTGGTGGCGGGCGCCTGTAATCCCAGCTACTCGGAAGGCTGAGGTGGGAGAATTGCTTAAACCCAGGA

>41207_41207_7_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000406337_IKBKB_chr8_42162705_ENST00000519735_length(amino acids)=216AA_BP=200
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKDPDNPGRIALPKPRNHGK
LDNKQNVDWNKLIKRAVEGLAESGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE

--------------------------------------------------------------
>41207_41207_8_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000406337_IKBKB_chr8_42162705_ENST00000520810_length(transcript)=3612nt_BP=1100nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGAT
TCTTTCTACTAATCCAGATACTTGTTGAAGTGCTGACTAGTTTCTTGGGGAAAGATGTCAAGGAAGAGTTGAAATTCCTAGACTGGCATA
AGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGAGTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTGAG
AAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTTGGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAAGG
AGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTTCCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTACTC
AGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTTCACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTT
TGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGATC
GTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGATC
CTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGATAA
AGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCAT
TATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGATG
GACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCTTC
TTCCACATGAAAAGGATAAGCCTCTGCGCTTAGATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCCAGAAAACATCGTCCT
GCAGCAAGGAGAACAGAGGTTAATACACAAAATTATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCTTTGCACATCATTCGT
GGGGACCCTGCAGTACCTGGCCCCAGAGCTACTGGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTTCGGCACCCTGGCCTT
TGAGTGCATCACGGGCTTCCGGCCCTTCCTCCCCAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAAGAGTGAGGTGGACAT
TGTTGTTAGCGAAGACTTGAATGGAACGGTGAAGTTTTCAAGCTCTTTACCCTACCCCAATAATCTTAACAGTGTCCTGGCTGAGCGACT
GGAGAAGTGGCTGCAACTGATGCTGATGTGGCACCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGGCTGCTTCAAGGCCCT
GGATGACATCTTAAACTTAAAGCTGGTTCATATCTTGAACATGGTCACGGGCACCATCCACACCTACCCTGTGACAGAGGATGAGAGTCT
GCAGAGCTTGAAGGCCAGAATCCAACAGGACACGGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGGCCTGGCGTTGATCCC
CGATAAGCCTGCCACTCAGTGTATTTCAGACGGCAAGTTAAATGAGGGCCACACATTGGACATGGATCTTGTTTTTCTCTTTGACAACAG
TAAAATCACCTATGAGACTCAGATCTCCCCACGGCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAAGAGGAATCTCGCCTT
CTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTGGCACAGCATCCAGACCCTGAAGGAAGATTGCAACCGGCTGCAGCAGGGACAGCGAGC
CGCCATGATGAATCTCCTCCGAAACAACAGCTGCCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCAGCTCAAGGCCAAGTT
GGATTTCTTCAAAACCAGCATCCAGATTGACCTGGAGAAGTACAGCGAGCAAACCGAGTTTGGGATCACATCAGATAAACTGCTGCTGGC
CTGGAGGGAAATGGAGCAGGCTGTGGAGCTCTGTGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGATGGCTCTGCAGACCGA
CATTGTGGACTTACAGAGGAGCCCCATGGGCCGGAAGCAGGGGGGAACGCTGGACGACCTAGAGGAGCAAGCAAGGGAGCTGTACAGGAG
ACTAAGGGAAAAACCTCGAGACCAGCGAACTGAGGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAATTCAGAGCTTCGAGAA
GAAAGTGCGAGTGATCTATACGCAGCTCAGTAAAACTGTGGTTTGCAAGCAGAAGGCGCTGGAACTGTTGCCCAAGGTGGAAGAGGTGGT
GAGCTTAATGAATGAGGATGAGAAGACTGTTGTCCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCTGAAGATTGCTTGTAG
CAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGATAGCATGAATGCCTCTCGACTTAGCCAGCCTGGGCAGCTGATGTCTCAGCCCTCCAC
GGCCTCCAACAGCTTACCTGAGCCAGCCAAGAAGAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCTGCTAGAAAATGCCAT
ACAGGACACTGTGAGGGAACAAGACCAGAGTTTCACGGCCCTAGACTGGAGCTGGTTACAGACGGAAGAAGAAGAGCACAGCTGCCTGGA
GCAGGCCTCATGATGTGGGGGGACTCGACCCCCTGACATGGGGCAGCCCATAGCAGGCCTTGTGCAGTGGGGGGACTCGACCCCCTGACA
TGGGGCTGCCTGGAGCAGGCCGCGTGACGTGGGGCTGCCTGGCCGCGGCTCTCACATGGTGGTTCCTGCTGCACTGATGGCCCAGGGGTC
TCTGGTATCCAGATGGAGCTCTCGCTTCCTCAGCAGCTGTGACTTTCACCCAGGACCCAGGACGCAGCCCTCCGTGGGCACTGCCGGCGC
CTTGTCTGCACACTGGAGGTCCTCCATTACAGAGGCCCAGCGCACATCGCTGGCCCCACAAACGTTCAGGGGTACAGCCATGGCAGCTCC
TTCCTCTGCCGTGAGAAAAGTGCTTGGAGTACGGTTTGCCACACACGTGACTGGACAGTGTCCAATTCAAATCTTTCAGGGCAGAGTCCG
AGCAGCGCTTGGTGACAGCCTGTCCTCTCCTGCTCTCCAAAGGCCCTGCTCCCTGTCCTCTCTCACTTTACAGCTTGTGTTTCTTCTGGA
TTCAGCTTCTCCTAAACAGACAGTTTAATTATAGTTGCGGCCTGGCCCCATCCTCACTTCCTCTTTTTATTTCACTGCTGCTAAAATTGT

>41207_41207_8_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000406337_IKBKB_chr8_42162705_ENST00000520810_length(amino acids)=604AA_BP=
MQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVD
IVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDES
LQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLA
FFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLL
AWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFE
KKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPS

--------------------------------------------------------------
>41207_41207_9_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000406337_IKBKB_chr8_42162705_ENST00000520835_length(transcript)=3068nt_BP=1100nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGAT
TCTTTCTACTAATCCAGATACTTGTTGAAGTGCTGACTAGTTTCTTGGGGAAAGATGTCAAGGAAGAGTTGAAATTCCTAGACTGGCATA
AGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGAGTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTGAG
AAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTTGGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAAGG
AGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTTCCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTACTC
AGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTTCACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGATTT
TGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGATC
GTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGATC
CTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGATAA
AGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGCAT
TATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGATG
GACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCTTC
TTCCACATGAAAAGGATAAGCCTCTGCGCTTAGATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCCAGAAAACATCGTCCT
GCAGCAAGGAGAACAGAGGTTAATACACAAAATTATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCTTTGCACATCATTCGT
GGGGACCCTGCAGTACCTGGCCCCAGAGCTACTGGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTTCGGCACCCTGGCCTT
TGAGTGCATCACGGGCTTCCGGCCCTTCCTCCCCAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAAGAGTGAGGTGGACAT
TGTTGTTAGCGAAGACTTGAATGGAACGGTGAAGTTTTCAAGCTCTTTACCCTACCCCAATAATCTTAACAGTGTCCTGGCTGAGCGACT
GGAGAAGTGGCTGCAACTGATGCTGATGTGGCACCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGGCTGCTTCAAGGCCCT
GGATGACATCTTAAACTTAAAGCTGGTTCATATCTTGAACATGGTCACGGGCACCATCCACACCTACCCTGTGACAGAGGATGAGAGTCT
GCAGAGCTTGAAGGCCAGAATCCAACAGGACACGGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGGCCTGGCGTTGATCCC
CGATAAGCCTGCCACTCAGTGTATTTCAGACGGCAAGTTAAATGAGGGCCACACATTGGACATGGATCTTGTTTTTCTCTTTGACAACAG
TAAAATCACCTATGAGACTCAGATCTCCCCACGGCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAAGAGGAATCTCGCCTT
CTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTGGCACAGCATCCAGACCCTGAAGGAAGATTGCAACCGGCTGCAGCAGGGACAGCGAGC
CGCCATGATGAATCTCCTCCGAAACAACAGCTGCCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCAGCTCAAGGCCAAGTT
GGATTTCTTCAAAACCAGCATCCAGATTGACCTGGAGAAGTACAGCGAGCAAACCGAGTTTGGGATCACATCAGATAAACTGCTGCTGGC
CTGGAGGGAAATGGAGCAGGCTGTGGAGCTCTGTGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGATGGCTCTGCAGACCGA
CATTGTGGACTTACAGAGGAGCCCCATGGGCCGGAAGCAGGGGGGAACGCTGGACGACCTAGAGGAGCAAGCAAGGGAGCTGTACAGGAG
ACTAAGGGAAAAACCTCGAGACCAGCGAACTGAGGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAATTCAGAGCTTCGAGAA
GAAAGTGCGAGTGATCTATACGCAGCTCAGTAAAACTGTGGTTTGCAAGCAGAAGGCGCTGGAACTGTTGCCCAAGGTGGAAGAGGTGGT
GAGCTTAATGAATGAGGATGAGAAGACTGTTGTCCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCTGAAGATTGCTTGTAG
CAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGATAGCATGAATGCCTCTCGACTTAGCCAGCCTGGGCAGCTGATGTCTCAGCCCTCCAC
GGCCTCCAACAGCTTACCTGAGCCAGCCAAGAAGAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCTGCTAGAAAATGCCAT
ACAGGACACTGTGAGGGAACAAGACCAGAGTTTCACGGCCCTAGACTGGAGCTGGTTACAGACGGAAGAAGAAGAGCACAGCTGCCTGGA
GCAGGCCTCATGATGTGGGGGGACTCGACCCCCTGACATGGGGCAGCCCATAGCAGGCCTTGTGCAGTGGGGGGACTCGACCCCCTGACA

>41207_41207_9_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000406337_IKBKB_chr8_42162705_ENST00000520835_length(amino acids)=604AA_BP=
MQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVD
IVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDES
LQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGKLNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLA
FFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLL
AWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFE
KKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPS

--------------------------------------------------------------
>41207_41207_10_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000485568_IKBKB_chr8_42146152_ENST00000520810_length(transcript)=3807nt_BP=1012nt
ACTGTCTCCAAGATGGCGGCCGTGTCAGTTTGGGGCATCTCCGCGGTCCGGCCCGGGGCCCCGGGATCTCGGCTGTCCTTCCTCCCGGCA
TAAGATGCACATTTTTCTGCTCTGGAGCCGGGAATGAAATATTCTTGAGTTCTTACAACTTTATGACGAGACCCATGTGTGGTGCTATTG
AGAAATTCATTGGGAAGTTGGAAGACATTTCAATCAACAGGTTGTTTTGGTTTCTATAGTACAATTGGGGTGGCATTCTGTTTTGTGAAA
GGAGGAAGGACTTAGGCCAGAAAACTCATATGCTATGGTTAACTGGTTCCCAGCCTCCGAGAATCTTGTTTTCCATGGTGTAAAACTTAC
TCAGCATCAGGATAAGGGATAACGACTCTATGGATATACAGAATCCTTCACCATGGTAAAACTCGCAAACCCGCTTTATACTGAGTGGAT
TTTGGAGGCCATCAAAAAAGTGAAAAAGCAGAAACAGCGTCCTTCAGAAGAAAGGATATGCAATGCTGTGTCTTCATCCCATGGCTTGGA
TCGTAAAACTGTTTTAGAACAATTGGAGTTGAGTGTTAAAGATGGAACAATTTTAAAAGTCTCAAATAAAGGACTCAATTCCTATAAAGA
TCCTGATAATCCTGGGCGAATAGCACTTCCTAAGCCTCGGAACCATGGAAAATTGGATAATAAACAAAATGTGGATTGGAATAAACTGAT
AAAGCGGGCAGTTGAGGGCTTGGCAGAGTCTGGTGGCTCAACTTTGAAAAGCATTGAACGTTTTTTGAAAGGTCAGAAGGATGTGTCTGC
ATTATTCGGAGGCAGTGCTGCCTCTGGCTTTCACCAGCAGTTACGATTGGCTATCAAACGTGCCATTGGCCACGGCAGACTCCTTAAAGA
TGGACCTCTTTATCGGCTCAACACTAAAGCAACCAACGTGGATGGGAAAGAGAGTTGTGAGTCTCTTTCCTGTTTACCTCCAGTGTCCCT
TCTTCCACATGAAAAGGATAAGGAAACAGGTGAGCAGATTGCCATCAAGCAGTGCCGGCAGGAGCTCAGCCCCCGGAACCGAGAGCGGTG
GTGCCTGGAGATCCAGATCATGAGAAGGCTGACCCACCCCAATGTGGTGGCTGCCCGAGATGTCCCTGAGGGGATGCAGAACTTGGCGCC
CAATGACCTGCCCCTGCTGGCCATGGAGTACTGCCAAGGAGGAGATCTCCGGAAGTACCTGAACCAGTTTGAGAACTGCTGTGGTCTGCG
GGAAGGTGCCATCCTCACCTTGCTGAGTGACATTGCCTCTGCGCTTAGATACCTTCATGAAAACAGAATCATCCATCGGGATCTAAAGCC
AGAAAACATCGTCCTGCAGCAAGGAGAACAGAGGTTAATACACAAAATTATTGACCTAGGATATGCCAAGGAGCTGGATCAGGGCAGTCT
TTGCACATCATTCGTGGGGACCCTGCAGTACCTGGCCCCAGAGCTACTGGAGCAGCAGAAGTACACAGTGACCGTCGACTACTGGAGCTT
CGGCACCCTGGCCTTTGAGTGCATCACGGGCTTCCGGCCCTTCCTCCCCAACTGGCAGCCCGTGCAGTGGCATTCAAAAGTGCGGCAGAA
GAGTGAGGTGGACATTGTTGTTAGCGAAGACTTGAATGGAACGGTGAAGTTTTCAAGCTCTTTACCCTACCCCAATAATCTTAACAGTGT
CCTGGCTGAGCGACTGGAGAAGTGGCTGCAACTGATGCTGATGTGGCACCCCCGACAGAGGGGCACGGATCCCACGTATGGGCCCAATGG
CTGCTTCAAGGCCCTGGATGACATCTTAAACTTAAAGCTGGTTCATATCTTGAACATGGTCACGGGCACCATCCACACCTACCCTGTGAC
AGAGGATGAGAGTCTGCAGAGCTTGAAGGCCAGAATCCAACAGGACACGGGCATCCCAGAGGAGGACCAGGAGCTGCTGCAGGAAGCGGG
CCTGGCGTTGATCCCCGATAAGCCTGCCACTCAGTGTATTTCAGACGGCAAGTTAAATGAGGGCCACACATTGGACATGGATCTTGTTTT
TCTCTTTGACAACAGTAAAATCACCTATGAGACTCAGATCTCCCCACGGCCCCAACCTGAAAGTGTCAGCTGTATCCTTCAAGAGCCCAA
GAGGAATCTCGCCTTCTTCCAGCTGAGGAAGGTGTGGGGCCAGGTCTGGCACAGCATCCAGACCCTGAAGGAAGATTGCAACCGGCTGCA
GCAGGGACAGCGAGCCGCCATGATGAATCTCCTCCGAAACAACAGCTGCCTCTCCAAAATGAAGAATTCCATGGCTTCCATGTCTCAGCA
GCTCAAGGCCAAGTTGGATTTCTTCAAAACCAGCATCCAGATTGACCTGGAGAAGTACAGCGAGCAAACCGAGTTTGGGATCACATCAGA
TAAACTGCTGCTGGCCTGGAGGGAAATGGAGCAGGCTGTGGAGCTCTGTGGGCGGGAGAACGAAGTGAAACTCCTGGTAGAACGGATGAT
GGCTCTGCAGACCGACATTGTGGACTTACAGAGGAGCCCCATGGGCCGGAAGCAGGGGGGAACGCTGGACGACCTAGAGGAGCAAGCAAG
GGAGCTGTACAGGAGACTAAGGGAAAAACCTCGAGACCAGCGAACTGAGGGTGACAGTCAGGAAATGGTACGGCTGCTGCTTCAGGCAAT
TCAGAGCTTCGAGAAGAAAGTGCGAGTGATCTATACGCAGCTCAGTAAAACTGTGGTTTGCAAGCAGAAGGCGCTGGAACTGTTGCCCAA
GGTGGAAGAGGTGGTGAGCTTAATGAATGAGGATGAGAAGACTGTTGTCCGGCTGCAGGAGAAGCGGCAGAAGGAGCTCTGGAATCTCCT
GAAGATTGCTTGTAGCAAGGTCCGTGGTCCTGTCAGTGGAAGCCCGGATAGCATGAATGCCTCTCGACTTAGCCAGCCTGGGCAGCTGAT
GTCTCAGCCCTCCACGGCCTCCAACAGCTTACCTGAGCCAGCCAAGAAGAGTGAAGAACTGGTGGCTGAAGCACATAACCTCTGCACCCT
GCTAGAAAATGCCATACAGGACACTGTGAGGGAACAAGACCAGAGTTTCACGGCCCTAGACTGGAGCTGGTTACAGACGGAAGAAGAAGA
GCACAGCTGCCTGGAGCAGGCCTCATGATGTGGGGGGACTCGACCCCCTGACATGGGGCAGCCCATAGCAGGCCTTGTGCAGTGGGGGGA
CTCGACCCCCTGACATGGGGCTGCCTGGAGCAGGCCGCGTGACGTGGGGCTGCCTGGCCGCGGCTCTCACATGGTGGTTCCTGCTGCACT
GATGGCCCAGGGGTCTCTGGTATCCAGATGGAGCTCTCGCTTCCTCAGCAGCTGTGACTTTCACCCAGGACCCAGGACGCAGCCCTCCGT
GGGCACTGCCGGCGCCTTGTCTGCACACTGGAGGTCCTCCATTACAGAGGCCCAGCGCACATCGCTGGCCCCACAAACGTTCAGGGGTAC
AGCCATGGCAGCTCCTTCCTCTGCCGTGAGAAAAGTGCTTGGAGTACGGTTTGCCACACACGTGACTGGACAGTGTCCAATTCAAATCTT
TCAGGGCAGAGTCCGAGCAGCGCTTGGTGACAGCCTGTCCTCTCCTGCTCTCCAAAGGCCCTGCTCCCTGTCCTCTCTCACTTTACAGCT
TGTGTTTCTTCTGGATTCAGCTTCTCCTAAACAGACAGTTTAATTATAGTTGCGGCCTGGCCCCATCCTCACTTCCTCTTTTTATTTCAC

>41207_41207_10_KAT6A-IKBKB_KAT6A_chr8_41905896_ENST00000485568_IKBKB_chr8_42146152_ENST00000520810_length(amino acids)=921AA_BP=188
MVKLANPLYTEWILEAIKKVKKQKQRPSEERICNAVSSSHGLDRKTVLEQLELSVKDGTILKVSNKGLNSYKDPDNPGRIALPKPRNHGK
LDNKQNVDWNKLIKRAVEGLAESGGSTLKSIERFLKGQKDVSALFGGSAASGFHQQLRLAIKRAIGHGRLLKDGPLYRLNTKATNVDGKE
SCESLSCLPPVSLLPHEKDKETGEQIAIKQCRQELSPRNRERWCLEIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLR
KYLNQFENCCGLREGAILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCTSFVGTLQYLAPELLE
QQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSEVDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHP
RQRGTDPTYGPNGCFKALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLALIPDKPATQCISDGK
LNEGHTLDMDLVFLFDNSKITYETQISPRPQPESVSCILQEPKRNLAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCL
SKMKNSMASMSQQLKAKLDFFKTSIQIDLEKYSEQTEFGITSDKLLLAWREMEQAVELCGRENEVKLLVERMMALQTDIVDLQRSPMGRK
QGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQSFEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVR
LQEKRQKELWNLLKIACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLENAIQDTVREQDQSFT

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for KAT6A-IKBKB


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217144_664200.02005.0PML
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171517_1741200.02005.0PML
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318144_664200.02005.0PML
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181517_1741200.02005.0PML
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318144_664200.02005.0PML
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181517_1741200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217144_664200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171517_1741200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318144_664200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181517_1741200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318144_664200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181517_1741200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217144_664200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171517_1741200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318144_664200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181517_1741200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318144_664200.02005.0PML
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181517_1741200.02005.0PML
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-217312_664200.02005.0RUNX1-1
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-318312_664200.02005.0RUNX1-1
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-318312_664200.02005.0RUNX1-1
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-217312_664200.02005.0RUNX1-1
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-318312_664200.02005.0RUNX1-1
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-318312_664200.02005.0RUNX1-1
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-217312_664200.02005.0RUNX1-1
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-318312_664200.02005.0RUNX1-1
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-318312_664200.02005.0RUNX1-1
HgeneKAT6Achr8:41905895chr8:42146151ENST00000265713-2171517_1642200.02005.0RUNX1-2
HgeneKAT6Achr8:41905895chr8:42146151ENST00000396930-3181517_1642200.02005.0RUNX1-2
HgeneKAT6Achr8:41905895chr8:42146151ENST00000406337-3181517_1642200.02005.0RUNX1-2
HgeneKAT6Achr8:41905896chr8:42146152ENST00000265713-2171517_1642200.02005.0RUNX1-2
HgeneKAT6Achr8:41905896chr8:42146152ENST00000396930-3181517_1642200.02005.0RUNX1-2
HgeneKAT6Achr8:41905896chr8:42146152ENST00000406337-3181517_1642200.02005.0RUNX1-2
HgeneKAT6Achr8:41905896chr8:42162705ENST00000265713-2171517_1642200.02005.0RUNX1-2
HgeneKAT6Achr8:41905896chr8:42162705ENST00000396930-3181517_1642200.02005.0RUNX1-2
HgeneKAT6Achr8:41905896chr8:42162705ENST00000406337-3181517_1642200.02005.0RUNX1-2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for KAT6A-IKBKB


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for KAT6A-IKBKB


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource