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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KAT6B-SDF4 (FusionGDB2 ID:41243)

Fusion Gene Summary for KAT6B-SDF4

check button Fusion gene summary
Fusion gene informationFusion gene name: KAT6B-SDF4
Fusion gene ID: 41243
HgeneTgene
Gene symbol

KAT6B

SDF4

Gene ID

23522

51150

Gene namelysine acetyltransferase 6Bstromal cell derived factor 4
SynonymsGTPTS|MORF|MOZ2|MYST4|ZC2HC6B|qkf|querkopfCab45|SDF-4
Cytomap

10q22.2

1p36.33

Type of geneprotein-codingprotein-coding
Descriptionhistone acetyltransferase KAT6BK(lysine) acetyltransferase 6BMOZ, YBF2/SAS3, SAS2 and TIP60 protein 4MOZ-related factorMYST histone acetyltransferase (monocytic leukemia) 4MYST-4histone acetyltransferase MORFhistone acetyltransferase MOZ2histone a45 kDa calcium-binding protein
Modification date2020031320200313
UniProtAcc

Q8WYB5

.
Ensembl transtripts involved in fusion geneENST00000287239, ENST00000372711, 
ENST00000372714, ENST00000372724, 
ENST00000372725, ENST00000490365, 
ENST00000459994, ENST00000263741, 
ENST00000360001, ENST00000545427, 
Fusion gene scores* DoF score23 X 21 X 10=48307 X 6 X 5=210
# samples 328
** MAII scorelog2(32/4830*10)=-3.91587937883577
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/210*10)=-1.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KAT6B [Title/Abstract] AND SDF4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKAT6B(76788745)-SDF4(1164117), # samples:1
Anticipated loss of major functional domain due to fusion event.KAT6B-SDF4 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
KAT6B-SDF4 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
KAT6B-SDF4 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
KAT6B-SDF4 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKAT6B

GO:0016573

histone acetylation

11965546

HgeneKAT6B

GO:0043966

histone H3 acetylation

16387653

HgeneKAT6B

GO:0045892

negative regulation of transcription, DNA-templated

10497217

HgeneKAT6B

GO:0045893

positive regulation of transcription, DNA-templated

10497217|11965546


check buttonFusion gene breakpoints across KAT6B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SDF4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChiTaRS5.0N/ABE938394KAT6Bchr10

76788745

+SDF4chr1

1164117

+


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Fusion Gene ORF analysis for KAT6B-SDF4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000287239ENST00000459994KAT6Bchr10

76788745

+SDF4chr1

1164117

+
5CDS-5UTRENST00000372711ENST00000459994KAT6Bchr10

76788745

+SDF4chr1

1164117

+
5CDS-5UTRENST00000372714ENST00000459994KAT6Bchr10

76788745

+SDF4chr1

1164117

+
5CDS-5UTRENST00000372724ENST00000459994KAT6Bchr10

76788745

+SDF4chr1

1164117

+
5CDS-5UTRENST00000372725ENST00000459994KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000287239ENST00000263741KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000287239ENST00000360001KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000287239ENST00000545427KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000372711ENST00000263741KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000372711ENST00000360001KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000372711ENST00000545427KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000372724ENST00000263741KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000372724ENST00000360001KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000372724ENST00000545427KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000372725ENST00000263741KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000372725ENST00000360001KAT6Bchr10

76788745

+SDF4chr1

1164117

+
Frame-shiftENST00000372725ENST00000545427KAT6Bchr10

76788745

+SDF4chr1

1164117

+
In-frameENST00000372714ENST00000263741KAT6Bchr10

76788745

+SDF4chr1

1164117

+
In-frameENST00000372714ENST00000360001KAT6Bchr10

76788745

+SDF4chr1

1164117

+
In-frameENST00000372714ENST00000545427KAT6Bchr10

76788745

+SDF4chr1

1164117

+
intron-3CDSENST00000490365ENST00000263741KAT6Bchr10

76788745

+SDF4chr1

1164117

+
intron-3CDSENST00000490365ENST00000360001KAT6Bchr10

76788745

+SDF4chr1

1164117

+
intron-3CDSENST00000490365ENST00000545427KAT6Bchr10

76788745

+SDF4chr1

1164117

+
intron-5UTRENST00000490365ENST00000459994KAT6Bchr10

76788745

+SDF4chr1

1164117

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000372714KAT6Bchr1076788745+ENST00000360001SDF4chr11164117+7030539339334071004
ENST00000372714KAT6Bchr1076788745+ENST00000263741SDF4chr11164117+7123539339334071004
ENST00000372714KAT6Bchr1076788745+ENST00000545427SDF4chr11164117+5946539339334071004

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000372714ENST00000360001KAT6Bchr1076788745+SDF4chr11164117+0.0025206620.9974794
ENST00000372714ENST00000263741KAT6Bchr1076788745+SDF4chr11164117+0.0025342530.9974657
ENST00000372714ENST00000545427KAT6Bchr1076788745+SDF4chr11164117+0.0023153770.9976846

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Fusion Genomic Features for KAT6B-SDF4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KAT6B-SDF4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:76788745/chr1:1164117)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KAT6B

Q8WYB5

.
FUNCTION: Histone acetyltransferase which may be involved in both positive and negative regulation of transcription. Required for RUNX2-dependent transcriptional activation. May be involved in cerebral cortex development. Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. {ECO:0000269|PubMed:10497217, ECO:0000269|PubMed:11965546, ECO:0000269|PubMed:16387653}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107111_1220349.0Calcium binding1
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107150_1610349.0Calcium binding2
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107209_2200349.0Calcium binding3
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107246_2570349.0Calcium binding4
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107291_3020349.0Calcium binding5
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107327_3380349.0Calcium binding6
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107111_1220363.0Calcium binding1
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107150_1610363.0Calcium binding2
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107209_2200363.0Calcium binding3
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107246_2570363.0Calcium binding4
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107291_3020363.0Calcium binding5
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107327_3380363.0Calcium binding6
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705111_1220203.0Calcium binding1
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705150_1610203.0Calcium binding2
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705209_2200203.0Calcium binding3
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705246_2570203.0Calcium binding4
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705291_3020203.0Calcium binding5
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705327_3380203.0Calcium binding6
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107137_1720349.0DomainEF-hand 2
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107197_2320349.0DomainEF-hand 3
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107233_2680349.0DomainEF-hand 4
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107278_3130349.0DomainEF-hand 5
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107314_3490349.0DomainEF-hand 6
TgeneSDF4chr10:76788745chr1:1164117ENST000002637410798_1330349.0DomainEF-hand 1
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107137_1720363.0DomainEF-hand 2
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107197_2320363.0DomainEF-hand 3
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107233_2680363.0DomainEF-hand 4
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107278_3130363.0DomainEF-hand 5
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107314_3490363.0DomainEF-hand 6
TgeneSDF4chr10:76788745chr1:1164117ENST000003600010798_1330363.0DomainEF-hand 1
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705137_1720203.0DomainEF-hand 2
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705197_2320203.0DomainEF-hand 3
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705233_2680203.0DomainEF-hand 4
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705278_3130203.0DomainEF-hand 5
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705314_3490203.0DomainEF-hand 6
TgeneSDF4chr10:76788745chr1:1164117ENST000005454270598_1330203.0DomainEF-hand 1
TgeneSDF4chr10:76788745chr1:1164117ENST0000026374107309_3620349.0RegionNecessary for intracellular retention in Golgi apparatus lumen
TgeneSDF4chr10:76788745chr1:1164117ENST0000036000107309_3620363.0RegionNecessary for intracellular retention in Golgi apparatus lumen
TgeneSDF4chr10:76788745chr1:1164117ENST0000054542705309_3620203.0RegionNecessary for intracellular retention in Golgi apparatus lumen

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+1181070_110402074.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+1181204_120702074.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+1181351_137302074.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+1181409_141702074.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+1181594_176302074.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+1181961_206102074.0Compositional biasNote=Met-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118492_53302074.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118521_52402074.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118599_60502074.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+1171070_110401891.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+1171204_120701891.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+1171351_137301891.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+1171409_141701891.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+1171594_176301891.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+1171961_206101891.0Compositional biasNote=Met-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117492_53301891.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117521_52401891.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117599_60501891.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+1171070_110401782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+1171204_120701782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+1171351_137301782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+1171409_141701782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+1171594_176301782.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+1171961_206101782.0Compositional biasNote=Met-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117492_53301782.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117521_52401782.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117599_60501782.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+1181070_110401782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+1181204_120701782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+1181351_137301782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+1181409_141701782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+1181594_176301782.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+1181961_206101782.0Compositional biasNote=Met-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118492_53301782.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118521_52401782.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118599_60501782.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+1171070_110401782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+1171204_120701782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+1171351_137301782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+1171409_141701782.0Compositional biasNote=Poly-Glu
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+1171594_176301782.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+1171961_206101782.0Compositional biasNote=Met-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117492_53301782.0Compositional biasNote=Ser-rich
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117521_52401782.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117599_60501782.0Compositional biasNote=Poly-Ser
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118103_17602074.0DomainH15
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118715_98902074.0DomainMYST-type HAT
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117103_17601891.0DomainH15
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117715_98901891.0DomainMYST-type HAT
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117103_17601782.0DomainH15
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117715_98901782.0DomainMYST-type HAT
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118103_17601782.0DomainH15
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118715_98901782.0DomainMYST-type HAT
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117103_17601782.0DomainH15
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117715_98901782.0DomainMYST-type HAT
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118361_71702074.0RegionNote=Negatively regulates HAT activity
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118718_100802074.0RegionNote=Catalytic
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118856_86002074.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118865_87102074.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117361_71701891.0RegionNote=Negatively regulates HAT activity
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117718_100801891.0RegionNote=Catalytic
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117856_86001891.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117865_87101891.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117361_71701782.0RegionNote=Negatively regulates HAT activity
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117718_100801782.0RegionNote=Catalytic
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117856_86001782.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117865_87101782.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118361_71701782.0RegionNote=Negatively regulates HAT activity
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118718_100801782.0RegionNote=Catalytic
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118856_86001782.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118865_87101782.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117361_71701782.0RegionNote=Negatively regulates HAT activity
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117718_100801782.0RegionNote=Catalytic
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117856_86001782.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117865_87101782.0RegionAcetyl-CoA binding
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118213_27202074.0Zinc fingerPHD-type 1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118269_32002074.0Zinc fingerPHD-type 2
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118748_77302074.0Zinc fingerC2HC MYST-type
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117213_27201891.0Zinc fingerPHD-type 1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117269_32001891.0Zinc fingerPHD-type 2
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117748_77301891.0Zinc fingerC2HC MYST-type
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117213_27201782.0Zinc fingerPHD-type 1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117269_32001782.0Zinc fingerPHD-type 2
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117748_77301782.0Zinc fingerC2HC MYST-type
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118213_27201782.0Zinc fingerPHD-type 1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118269_32001782.0Zinc fingerPHD-type 2
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118748_77301782.0Zinc fingerC2HC MYST-type
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117213_27201782.0Zinc fingerPHD-type 1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117269_32001782.0Zinc fingerPHD-type 2
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117748_77301782.0Zinc fingerC2HC MYST-type


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Fusion Gene Sequence for KAT6B-SDF4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>41243_41243_1_KAT6B-SDF4_KAT6B_chr10_76788745_ENST00000372714_SDF4_chr1_1164117_ENST00000263741_length(transcript)=7123nt_BP=5393nt
ACAAAATGGCGGCGGCTTAGCTCCTACCCCTGGCGGCGGCGGCAGCGGTGGCGGAGGCGACGGCACCTCCTCCAGGCGGCAGCCGCAGTT
TCTCAGGCAGCGGCAGCGCCCCCGGCAGGCGCGGTGGCGGTGGCGCGCAGCCAGGTCTTGATTTCCCAGTTAAAGATGTTCTTCACCCGA
ATGCAGTCTTTCCTGTTGGTAAAATAAGACAACCATCAACATTGCCTGTTTGTCTGCTTTTGAATCTCTTAAGGATGGATGTTTGTAAGA
TGTTGCTTAATACAGTCTGGAATACTCTGTCCATTTGTTGAATTGTAAATGACTTTCAAATGTGCAAGTTCTGTTAAATACAAAGAGAAC
CTCTATGGGTAACTTTTGTGTTGAAGAAGTCATTTGTCAACCATGGTAAAACTTGCAAACCCACTTTATACAGAGTGGATTCTTGAAGCT
ATACAGAAAATAAAAAAGCAAAAGCAAAGGCCCTCTGAAGAGAGAATCTGCCATGCGGTCAGTACTTCCCATGGGTTGGATAAGAAGACA
GTCTCTGAACAGCTGGAACTCAGTGTTCAGGATGGCTCAGTTCTCAAAGTCACCAACAAAGGCCTTGCCTCCTATAAGGACCCAGACAAC
CCTGGGCGCTTTTCATCAGTTAAACCAGGCACTTTTCCTAAGTCAGCCAAGGGGTCTAGAGGATCATGTAATGATCTCCGCAATGTGGAT
TGGAATAAACTTTTAAGGAGAGCAATTGAAGGACTTGAGGAGCCGAATGGCTCCTCCCTGAAGAACATAGAGAAGTATCTCAGAAGTCAA
AGTGATCTCACAAGCACCACCAACAACCCAGCCTTTCAGCAGCGGCTGCGACTGGGGGCCAAACGCGCTGTGAATAATGGGAGGTTACTG
AAAGACGGACCGCAGTACAGGGTCAATTATGGGAGCTTAGATGGCAAAGGGGCACCTCAGTATCCCAGTGCATTCCCATCCTCGCTCCCA
CCTGTCAGCCTTCTACCCCATGAGAAAGACCAGCCCCGTGCTGATCCCATTCCAATATGTAGCTTCTGTTTGGGGACTAAAGAATCAAAT
CGTGAAAAGAAACCAGAAGAACTCCTCTCTTGTGCAGATTGTGGCAGTAGTGGACACCCATCCTGTTTGAAATTTTGTCCTGAATTAACA
ACAAATGTAAAGGCCTTAAGGTGGCAGTGCATCGAATGCAAGACATGCAGTGCCTGTAGAGTCCAAGGCAGAAATGCTGATAATATGCTT
TTTTGTGATTCCTGTGATAGAGGATTTCATATGGAATGCTGTGACCCACCACTTTCCAGAATGCCAAAAGGGATGTGGATTTGCCAAGTC
TGCAGACCAAAGAAAAAGGGAAGAAAACTACTTCATGAGAAAGCTGCACAAATAAAACGACGATATGCAAAACCCATTGGACGACCGAAA
AATAAATTAAAGCAACGATTGTTGTCTGTAACCAGTGATGAAGGATCCATGAATGCATTCACAGGAAGGGGGTCACCTGATACTGAAATA
AAAATAAACATCAAACAAGAAAGTGCAGATGTAAATGTGATTGGAAACAAGGATGTCGTTACTGAAGAGGATTTGGATGTTTTTAAGCAG
GCCCAGGAACTTTCTTGGGAGAAAATAGAGTGTGAGAGTGGGGTGGAAGACTGTGGCCGGTACCCTTCTGTGATTGAATTTGGTAAATAT
GAAATCCAAACCTGGTACTCCTCGCCTTACCCACAGGAATATGCAAGATTACCAAAGCTTTACCTGTGTGAATTCTGTCTTAAATATATG
AAAAGTAAAAATATTTTGCTAAGACACTCCAAGAAGTGTGGATGGTTTCATCCTCCAGCAAATGAAATTTACCGAAGGAAAGACCTTTCA
GTATTTGAGGTTGATGGGAATATGAGCAAAATTTATTGCCAAAACCTTTGCTTGTTAGCCAAGCTCTTCCTGGACCACAAAACGTTGTAT
TATGATGTCGAGCCATTCCTTTTTTATGTCCTTACAAAAAATGATGAAAAGGGCTGTCATCTGGTTGGATACTTCTCTAAGGAAAAGCTT
TGCCAGCAGAAGTATAATGTCTCCTGCATAATGATCATGCCCCAGCACCAAAGGCAAGGATTTGGACGGTTTCTCATTGATTTCAGCTAT
TTGCTTTCTAGAAGAGAAGGCCAAGCAGGGTCTCCTGAAAAGCCTCTCTCCGATCTGGGCCGTCTCTCCTACCTGGCATATTGGAAGAGC
GTCATCTTGGAGTATCTCTACCACCACCATGAGAGGCACATCAGCATCAAGGCAATTAGCAGAGCGACGGGCATGTGCCCACATGACATT
GCCACCACTCTGCAGCACCTCCACATGATCGACAAGAGAGATGGCAGATTTGTCATCATTAGACGGGAAAAGTTGATATTGAGCCACATG
GAAAAGCTGAAAACCTGTTCCAGAGCCAATGAACTTGATCCAGACAGTCTGAGGTGGACCCCAATTTTAATTTCTAATGCTGCAGTGTCT
GAAGAAGAGCGAGAAGCTGAGAAAGAGGCTGAGCGGCTAATGGAACAAGCTAGCTGCTGGGAGAAGGAGGAACAAGAAATCCTGTCAACT
AGAGCTAACAGTAGGCAATCACCTGCAAAAGTACAATCGAAAAATAAATATTTGCATTCCCCGGAGAGCCGGCCAGTCACAGGGGAGCGA
GGGCAGCTGCTGGAGCTGTCTAAAGAGAGCAGTGAAGAAGAAGAGGAGGAGGAGGACGAGGAGGAGGAAGAAGAGGAGGAAGAAGAGGAA
GAGGATGAAGAGGAGGAAGAAGAGGAAGAAGAAGAAGAAGAAGAAGAAAATATTCAAAGCTCTCCCCCAAGATTGACGAAACCACAGTCA
GTTGCCATAAAGAGAAAGAGGCCTTTTGTACTAAAGAAGAAAAGGGGTCGTAAACGCAGGAGGATCAACAGCAGTGTAACAACAGAGACC
ATTTCAGAGACGACAGAAGTACTGAATGAGCCCTTTGACAACTCAGATGAAGAGAGGCCAATGCCACAGCTGGAGCCTACCTGTGAGATT
GAAGTGGAGGAAGATGGCAGGAAGCCAGTCCTGAGAAAAGCATTCCAGCATCAGCCTGGGAAGAAAAGACAAACAGAGGAAGAGGAAGGA
AAAGACAATCATTGCTTCAAGAATGCTGACCCTTGTAGAAAGAAAAAGAGGAACCAGAAATCTCCACGGAAAAAGAAGACTCTGCACGTT
TGGATGATCACGAAGAGGAGGAGGAAGAGGATGAAGAGCCATCCCACAACGAGGACCATGATGCCGATGACGAGGATGACAGCCACATGG
AGTCTGCCGAAGTGGAGAAGGAAGAGCTGCCCAGAGAAAGCTTCAAAGAAGTACTGGAAAACCAGGAGACTTTTTTAGACCTTAATGTGC
AGCCTGGTCACTCGAACCCAGAGGTCTTAATGGACTGTGGCGTCGACCTGACAGCTTCTTGTAACAGTGAGCCCAAGGAGCTTGCTGGGG
ACCCTGAAGCTGTACCCGAATCTGACGAGGAGCCACCCCCAGGAGAACAGGCACAGAAGCAGGACCAAAAGAACAGCAAGGAAGTCGATA
CAGAGTTCAAAGAGGGAAACCCAGCAACCATGGAAATCGACTCTGAGACTGTCCAGGCCGTTCAGTCTTTGACCCAGGAGAGCAGCGAAC
AGGACGACACCTTTCAGGATTGTGCCGAGACTCAAGAGGCCTGTAGAAGCCTACAGAACTACACCCGTGCAGACCAAAGTCCACAGATTG
CCACCACGCTCGACGATTGCCAACAGTCGGACCACAGTAGCCCAGTTTCATCCGTCCACTCCCATCCTGGCCAGTCCGTACGTTCTGTCA
ACAGCCCAAGTGTCCCTGCTCTGGAAAACAGCTACGCCCAAATCAGCCCAGATCAAAGTGCCATCTCAGTGCCATCTCTGCAGAACATGG
AAACCAGTCCCATGATGGATGTCCCATCAGTTTCAGATCATTCACAGCAAGTCGTAGACAGTGGATTTAGTGACCTGGGCAGTATCGAGA
GCACAACTGAGAACTACGAAAACCCAAGCAGCTACGATTCTACTATGGGAGGCAGCATCTGTGGAAACGGCTCTTCACAGAACAGCTGCT
CCTATAGCAACCTCACCTCCAGCAGTCTGACACAGAGCAGCTGTGCTGTCACCCAGCAGATGTCCAACATCAGCGGGAGCTGCAGCATGC
TGCAGCAAACCAGCATCAGCTCCCCTCCGACCTGCAGCGTCAAGTCTCCTCAAGGCTGTGTGGTGGAGAGGCCTCCGAGCAGCAGCCAGC
AGCTGGCTCAGTGCAGCATGGCTGCTAACTTCACCCCACCCATGCAGCTGGCTGAAATCCCCGAGACGAGCAACGCCAACATTGGCTTAT
ACGAGCGAATGGGTCAGAGTGATTTTGGGGCTGGGCATTACCCGCAGCCGTCAGCCACCTTCAGCCTTGCCAAACTGCAGCAGTTAACTA
ATACACTTATTGATCATTCATTGCCTTACAGCCATTCCGCTGCTGTGACTTCCTATGCAAACAGTGCCTCTTTGTCCACACCATTAAGTA
ACACAGGGCTTGTTCAACTTTCTCAGTCTCCACACTCCGTCCCTGGGGGACCCCAAGCACAAGCTACCATGACCCCACCCCCCAACCTGA
CTCCTCCTCCAATGAATCTGCCGCCGCCTCTTTTGCAACGGAACATGGCTGCATCAAATATTGGCATCTCTCACAGCCAAAGACTGCAAA
CCCAGATTGCCAGCAAGGGCCACATCTCCATGAGAACCAAGTCAGCGTCTCTGTCACCAGCCGCTGCCACCCATCAGTCACAAATCTATG
GGCGCTCCCAGACTGTAGCCATGCAGGGTCCTGCACGGACTTTAACGATGCAAAGAGGCATGAACATGAGTGTGAACCTGATGCCAGCGC
CAGCCTACAATGTCAACTCTGTGAACATGAACATGAACACTCTCAACGCCATGAATGGGTACAGCATGTCCCAGCCAATGATGAACAGTG
GCTACCACAGCAATCATGGCTATATGAATCAAACGCCCCAATACCCTATGCAGATGCAGATGGGCATGATGGGCACCCAGCCATATGCCC
AGCAGCCAATGCAGACCCCACCCCACGGTAACATGATGTACACGGCCCCCGGACATCACGGCTACATGAACACAGGCATGTCCAAACAGT
CTCTCAATGGCTCCTACATGAGAAGGTAGACAACGTGGGCAGTCCACAAAACCTACGGGGCATCACTATTGGATTGATCTGCACAAATAC
CTTTGAAGAGTACGATTTCAAAACCAGCAATTGGTGTGAATGCAAAAACATTTGTTGGCACCATTTATTTAAAAAAAAAAAAAAACGTGC
CCACACTCCCGCTGCAGCCAATAGGCACCTTAAATAGCCACTTCGTGCGGCTGGCCGCGGAGCTCGGAGGGGGAAAGGCGACGCTGACCT
GTGCCCCGCTCGCCCGCAGAGCTACATGGACCCCATGAACGAGTACAACGCGCTGAACGAGGCCAAGCAGATGATCGCCGTCGCCGACGA
GAACCAGAACCACCACCTGGAGCCCGAGGAGGTGCTCAAGTACAGCGAGTTCTTCACGGGCAGCAAGCTGGTGGACTACGCGCGCAGCGT
GCACGAGGAGTTTTGAGCGCCCGGCCGCGCCCCGCGCCGCCCCCCACGCACCACCGGGGCGGCCTCGCGGGTGACTCCGGGCTCCGTGGC
TGTCCCGGACCCCACCTCTTCCCTGCCGCCCGCCACCGGCCGACCGACCGCGGCTGCCCCAGTTGATGAGCGGCGTGTCCCCTCTGCAGC
GCGCACCCCGGCGGGGCTTTGGCTGTGACGCGGTCGGGGCGCGGGGCTGGGCTGTGGCCCCGCGGCGCCGCCTCCTCCCTGGTCCCTCGA
AATCGTGGCATCTCACTTCTGAGAACGAAATCTCGCTTCAGTCACTCTGCCGAAGGCGCTGACGGCATCGCGGCCGGAACCTCTGGGCCC
GGCCCCTCCCAGGGCCGCCGCTCCGTGGGAAAAAACAGCTCCTCCATTTCCTTGAAAACTGAACGATTATTAAAAATAGATTAAACTTCG
CTGGAAATGAGTAGCCAGGAAGTTCAGGGGAGGGTGCCGGGTCCTTCCCGGGCCTGGCGTGTCGGAGCCACCCAGGTCCCGCAGCTGCCG
CTGAGAAAATGCAAATATTTGTTGTGACAAGAATCACATACATTTACTTTAAATATAACCAGGACGGTGACAAGCAGCTCTCTGTGCCCG
AGTTCATCTCCCTGCCCGTGGGCACCGTGGAGAACCAGCAGGGCCAGGACATTGACGACAACTGGGTGAAAGACAGAAAAAAGGAGTTTG
AGGAGCTCATTGACTCCAACCACGACGGCATCGTGACCGCCGAGGAGCTGGAGCACAGGAAGTCCTGGAGAACCTGAAGGACCGCTGGTA
CCAGGCGGACAGCCCCCCTGCAGACCTGCTGCTGACGGAGGAGGAGTTCCTGTCGTTCCTCCACCCCGAGCACAGCCGGGGAATGCTCAG
GTTCATGGTGAAGGAGATCGTCCGGGACCTGGGTCACGTGTCTTGGGACGAGTATAAGGTGAAGTTTTTGGCGAGTAAAGGCCATAGCGA
GAAGGAGGTTGCCGACGCCATCAGGCTCAACGAGGAACTCAAAGTGGATGAGGAAAGGTGGATGTGAACACTGACCGGAAGATCAGTGCC
AAGGAGATGCAGCGCTGGATCATGGAGAAGACGGCCGAGCACTTCCAGGAGGCCATGGAGGAGAGCAAGACACACTTCCGCGCCGTGGAC
CCTGACGGGGACGTCCGTGCTGCCTCTGGCTCCTGGGGGCAGTCCTTCTGATGGACGCGTCTGCACGGCCTGCCAACCACTCGTCCACTC
GAGAGAGAGTAGCCAACAGGGAGGAGAATGAGATCCTGCCCCCAGACCACCTGAACGGGGTGAAGCTGGAGATGGACGGGCACCTCAATC
GCGGCTTCCACCAGGAGGTCTTCCTAGGCAAGGACCTGGGTGGCTTTGATGAGGACGCGGAGCCGCGGCGGAGCCGGAGGAAGCTGATGG

>41243_41243_1_KAT6B-SDF4_KAT6B_chr10_76788745_ENST00000372714_SDF4_chr1_1164117_ENST00000263741_length(amino acids)=1004AA_BP=
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYHHHE
RHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAE
RLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE
EEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVL
RKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRKKKRNQKSPRKKKTLHVWMITKRRRKRMKSHPTTRTMMPMTRMTATWSLPKWRRKSCP

--------------------------------------------------------------
>41243_41243_2_KAT6B-SDF4_KAT6B_chr10_76788745_ENST00000372714_SDF4_chr1_1164117_ENST00000360001_length(transcript)=7030nt_BP=5393nt
ACAAAATGGCGGCGGCTTAGCTCCTACCCCTGGCGGCGGCGGCAGCGGTGGCGGAGGCGACGGCACCTCCTCCAGGCGGCAGCCGCAGTT
TCTCAGGCAGCGGCAGCGCCCCCGGCAGGCGCGGTGGCGGTGGCGCGCAGCCAGGTCTTGATTTCCCAGTTAAAGATGTTCTTCACCCGA
ATGCAGTCTTTCCTGTTGGTAAAATAAGACAACCATCAACATTGCCTGTTTGTCTGCTTTTGAATCTCTTAAGGATGGATGTTTGTAAGA
TGTTGCTTAATACAGTCTGGAATACTCTGTCCATTTGTTGAATTGTAAATGACTTTCAAATGTGCAAGTTCTGTTAAATACAAAGAGAAC
CTCTATGGGTAACTTTTGTGTTGAAGAAGTCATTTGTCAACCATGGTAAAACTTGCAAACCCACTTTATACAGAGTGGATTCTTGAAGCT
ATACAGAAAATAAAAAAGCAAAAGCAAAGGCCCTCTGAAGAGAGAATCTGCCATGCGGTCAGTACTTCCCATGGGTTGGATAAGAAGACA
GTCTCTGAACAGCTGGAACTCAGTGTTCAGGATGGCTCAGTTCTCAAAGTCACCAACAAAGGCCTTGCCTCCTATAAGGACCCAGACAAC
CCTGGGCGCTTTTCATCAGTTAAACCAGGCACTTTTCCTAAGTCAGCCAAGGGGTCTAGAGGATCATGTAATGATCTCCGCAATGTGGAT
TGGAATAAACTTTTAAGGAGAGCAATTGAAGGACTTGAGGAGCCGAATGGCTCCTCCCTGAAGAACATAGAGAAGTATCTCAGAAGTCAA
AGTGATCTCACAAGCACCACCAACAACCCAGCCTTTCAGCAGCGGCTGCGACTGGGGGCCAAACGCGCTGTGAATAATGGGAGGTTACTG
AAAGACGGACCGCAGTACAGGGTCAATTATGGGAGCTTAGATGGCAAAGGGGCACCTCAGTATCCCAGTGCATTCCCATCCTCGCTCCCA
CCTGTCAGCCTTCTACCCCATGAGAAAGACCAGCCCCGTGCTGATCCCATTCCAATATGTAGCTTCTGTTTGGGGACTAAAGAATCAAAT
CGTGAAAAGAAACCAGAAGAACTCCTCTCTTGTGCAGATTGTGGCAGTAGTGGACACCCATCCTGTTTGAAATTTTGTCCTGAATTAACA
ACAAATGTAAAGGCCTTAAGGTGGCAGTGCATCGAATGCAAGACATGCAGTGCCTGTAGAGTCCAAGGCAGAAATGCTGATAATATGCTT
TTTTGTGATTCCTGTGATAGAGGATTTCATATGGAATGCTGTGACCCACCACTTTCCAGAATGCCAAAAGGGATGTGGATTTGCCAAGTC
TGCAGACCAAAGAAAAAGGGAAGAAAACTACTTCATGAGAAAGCTGCACAAATAAAACGACGATATGCAAAACCCATTGGACGACCGAAA
AATAAATTAAAGCAACGATTGTTGTCTGTAACCAGTGATGAAGGATCCATGAATGCATTCACAGGAAGGGGGTCACCTGATACTGAAATA
AAAATAAACATCAAACAAGAAAGTGCAGATGTAAATGTGATTGGAAACAAGGATGTCGTTACTGAAGAGGATTTGGATGTTTTTAAGCAG
GCCCAGGAACTTTCTTGGGAGAAAATAGAGTGTGAGAGTGGGGTGGAAGACTGTGGCCGGTACCCTTCTGTGATTGAATTTGGTAAATAT
GAAATCCAAACCTGGTACTCCTCGCCTTACCCACAGGAATATGCAAGATTACCAAAGCTTTACCTGTGTGAATTCTGTCTTAAATATATG
AAAAGTAAAAATATTTTGCTAAGACACTCCAAGAAGTGTGGATGGTTTCATCCTCCAGCAAATGAAATTTACCGAAGGAAAGACCTTTCA
GTATTTGAGGTTGATGGGAATATGAGCAAAATTTATTGCCAAAACCTTTGCTTGTTAGCCAAGCTCTTCCTGGACCACAAAACGTTGTAT
TATGATGTCGAGCCATTCCTTTTTTATGTCCTTACAAAAAATGATGAAAAGGGCTGTCATCTGGTTGGATACTTCTCTAAGGAAAAGCTT
TGCCAGCAGAAGTATAATGTCTCCTGCATAATGATCATGCCCCAGCACCAAAGGCAAGGATTTGGACGGTTTCTCATTGATTTCAGCTAT
TTGCTTTCTAGAAGAGAAGGCCAAGCAGGGTCTCCTGAAAAGCCTCTCTCCGATCTGGGCCGTCTCTCCTACCTGGCATATTGGAAGAGC
GTCATCTTGGAGTATCTCTACCACCACCATGAGAGGCACATCAGCATCAAGGCAATTAGCAGAGCGACGGGCATGTGCCCACATGACATT
GCCACCACTCTGCAGCACCTCCACATGATCGACAAGAGAGATGGCAGATTTGTCATCATTAGACGGGAAAAGTTGATATTGAGCCACATG
GAAAAGCTGAAAACCTGTTCCAGAGCCAATGAACTTGATCCAGACAGTCTGAGGTGGACCCCAATTTTAATTTCTAATGCTGCAGTGTCT
GAAGAAGAGCGAGAAGCTGAGAAAGAGGCTGAGCGGCTAATGGAACAAGCTAGCTGCTGGGAGAAGGAGGAACAAGAAATCCTGTCAACT
AGAGCTAACAGTAGGCAATCACCTGCAAAAGTACAATCGAAAAATAAATATTTGCATTCCCCGGAGAGCCGGCCAGTCACAGGGGAGCGA
GGGCAGCTGCTGGAGCTGTCTAAAGAGAGCAGTGAAGAAGAAGAGGAGGAGGAGGACGAGGAGGAGGAAGAAGAGGAGGAAGAAGAGGAA
GAGGATGAAGAGGAGGAAGAAGAGGAAGAAGAAGAAGAAGAAGAAGAAAATATTCAAAGCTCTCCCCCAAGATTGACGAAACCACAGTCA
GTTGCCATAAAGAGAAAGAGGCCTTTTGTACTAAAGAAGAAAAGGGGTCGTAAACGCAGGAGGATCAACAGCAGTGTAACAACAGAGACC
ATTTCAGAGACGACAGAAGTACTGAATGAGCCCTTTGACAACTCAGATGAAGAGAGGCCAATGCCACAGCTGGAGCCTACCTGTGAGATT
GAAGTGGAGGAAGATGGCAGGAAGCCAGTCCTGAGAAAAGCATTCCAGCATCAGCCTGGGAAGAAAAGACAAACAGAGGAAGAGGAAGGA
AAAGACAATCATTGCTTCAAGAATGCTGACCCTTGTAGAAAGAAAAAGAGGAACCAGAAATCTCCACGGAAAAAGAAGACTCTGCACGTT
TGGATGATCACGAAGAGGAGGAGGAAGAGGATGAAGAGCCATCCCACAACGAGGACCATGATGCCGATGACGAGGATGACAGCCACATGG
AGTCTGCCGAAGTGGAGAAGGAAGAGCTGCCCAGAGAAAGCTTCAAAGAAGTACTGGAAAACCAGGAGACTTTTTTAGACCTTAATGTGC
AGCCTGGTCACTCGAACCCAGAGGTCTTAATGGACTGTGGCGTCGACCTGACAGCTTCTTGTAACAGTGAGCCCAAGGAGCTTGCTGGGG
ACCCTGAAGCTGTACCCGAATCTGACGAGGAGCCACCCCCAGGAGAACAGGCACAGAAGCAGGACCAAAAGAACAGCAAGGAAGTCGATA
CAGAGTTCAAAGAGGGAAACCCAGCAACCATGGAAATCGACTCTGAGACTGTCCAGGCCGTTCAGTCTTTGACCCAGGAGAGCAGCGAAC
AGGACGACACCTTTCAGGATTGTGCCGAGACTCAAGAGGCCTGTAGAAGCCTACAGAACTACACCCGTGCAGACCAAAGTCCACAGATTG
CCACCACGCTCGACGATTGCCAACAGTCGGACCACAGTAGCCCAGTTTCATCCGTCCACTCCCATCCTGGCCAGTCCGTACGTTCTGTCA
ACAGCCCAAGTGTCCCTGCTCTGGAAAACAGCTACGCCCAAATCAGCCCAGATCAAAGTGCCATCTCAGTGCCATCTCTGCAGAACATGG
AAACCAGTCCCATGATGGATGTCCCATCAGTTTCAGATCATTCACAGCAAGTCGTAGACAGTGGATTTAGTGACCTGGGCAGTATCGAGA
GCACAACTGAGAACTACGAAAACCCAAGCAGCTACGATTCTACTATGGGAGGCAGCATCTGTGGAAACGGCTCTTCACAGAACAGCTGCT
CCTATAGCAACCTCACCTCCAGCAGTCTGACACAGAGCAGCTGTGCTGTCACCCAGCAGATGTCCAACATCAGCGGGAGCTGCAGCATGC
TGCAGCAAACCAGCATCAGCTCCCCTCCGACCTGCAGCGTCAAGTCTCCTCAAGGCTGTGTGGTGGAGAGGCCTCCGAGCAGCAGCCAGC
AGCTGGCTCAGTGCAGCATGGCTGCTAACTTCACCCCACCCATGCAGCTGGCTGAAATCCCCGAGACGAGCAACGCCAACATTGGCTTAT
ACGAGCGAATGGGTCAGAGTGATTTTGGGGCTGGGCATTACCCGCAGCCGTCAGCCACCTTCAGCCTTGCCAAACTGCAGCAGTTAACTA
ATACACTTATTGATCATTCATTGCCTTACAGCCATTCCGCTGCTGTGACTTCCTATGCAAACAGTGCCTCTTTGTCCACACCATTAAGTA
ACACAGGGCTTGTTCAACTTTCTCAGTCTCCACACTCCGTCCCTGGGGGACCCCAAGCACAAGCTACCATGACCCCACCCCCCAACCTGA
CTCCTCCTCCAATGAATCTGCCGCCGCCTCTTTTGCAACGGAACATGGCTGCATCAAATATTGGCATCTCTCACAGCCAAAGACTGCAAA
CCCAGATTGCCAGCAAGGGCCACATCTCCATGAGAACCAAGTCAGCGTCTCTGTCACCAGCCGCTGCCACCCATCAGTCACAAATCTATG
GGCGCTCCCAGACTGTAGCCATGCAGGGTCCTGCACGGACTTTAACGATGCAAAGAGGCATGAACATGAGTGTGAACCTGATGCCAGCGC
CAGCCTACAATGTCAACTCTGTGAACATGAACATGAACACTCTCAACGCCATGAATGGGTACAGCATGTCCCAGCCAATGATGAACAGTG
GCTACCACAGCAATCATGGCTATATGAATCAAACGCCCCAATACCCTATGCAGATGCAGATGGGCATGATGGGCACCCAGCCATATGCCC
AGCAGCCAATGCAGACCCCACCCCACGGTAACATGATGTACACGGCCCCCGGACATCACGGCTACATGAACACAGGCATGTCCAAACAGT
CTCTCAATGGCTCCTACATGAGAAGGTAGACAACGTGGGCAGTCCACAAAACCTACGGGGCATCACTATTGGATTGATCTGCACAAATAC
CTTTGAAGAGTACGATTTCAAAACCAGCAATTGGTGTGAATGCAAAAACATTTGTTGGCACCATTTATTTAAAAAAAAAAAAAAGCTACA
TGGACCCCATGAACGAGTACAACGCGCTGAACGAGGCCAAGCAGATGATCGCCGTCGCCGACGAGAACCAGAACCACCACCTGGAGCCCG
AGGAGGTGCTCAAGTACAGCGAGTTCTTCACGGGCAGCAAGCTGGTGGACTACGCGCGCAGCGTGCACGAGGAGTTTTGAGCGCCCGGCC
GCGCCCCGCGCCGCCCCCCACGCACCACCGGGGCGGCCTCGCGGGTGACTCCGGGCTCCGTGGCTGTCCCGGACCCCACCTCTTCCCTGC
CGCCCGCCACCGGCCGACCGACCGCGGCTGCCCCAGTTGATGAGCGGCGTGTCCCCTCTGCAGCGCGCACCCCGGCGGGGCTTTGGCTGT
GACGCGGTCGGGGCGCGGGGCTGGGCTGTGGCCCCGCGGCGCCGCCTCCTCCCTGGTCCCTCGAAATCGTGGCATCTCACTTCTGAGAAC
GAAATCTCGCTTCAGTCACTCTGCCGAAGGCGCTGACGGCATCGCGGCCGGAACCTCTGGGCCCGGCCCCTCCCAGGGCCGCCGCTCCGT
GGGAAAAAACAGCTCCTCCATTTCCTTGAAAACTGAACGATTATTAAAAATAGATTAAACTTCGCTGGAAATGAGTAGCCAGGAAGTTCA
GGGGAGGGTGCCGGGTCCTTCCCGGGCCTGGCGTGTCGGAGCCACCCAGGTCCCGCAGCTGCCGCTGAGAAAATGCAAATATTTGTTGTG
ACAAGAATCACATACATTTACTTTAAATATAGTTGCCTTTTTTGGTCAGCTTCAACCAGGACGGTGACAAGCAGCTCTCTGTGCCCGAGT
TCATCTCCCTGCCCGTGGGCACCGTGGAGAACCAGCAGGGCCAGGACATTGACGACAACTGGGTGAAAGACAGAAAAAAGGAGTTTGAGG
AGCTCATTGACTCCAACCACGACGGCATCGTGACCGCCGAGGAGCTGGAGCACAGGAAGTCCTGGAGAACCTGAAGGACCGCTGGTACCA
GGCGGACAGCCCCCCTGCAGACCTGCTGCTGACGGAGGAGGAGTTCCTGTCGTTCCTCCACCCCGAGCACAGCCGGGGAATGCTCAGGTT
CATGGTGAAGGAGATCGTCCGGGACCTGGGTCACGTGTCTTGGGACGAGTATAAGGTGAAGTTTTTGGCGAGTAAAGGCCATAGCGAGAA
GGAGGTTGCCGACGCCATCAGGCTCAACGAGGAACTCAAAGTGGATGAGGAAAGGTGGATGTGAACACTGACCGGAAGATCAGTGCCAAG
GAGATGCAGCGCTGGATCATGGAGAAGACGGCCGAGCACTTCCAGGAGGCCATGGAGGAGAGCAAGACACACTTCCGCGCCGTGGACCCT
GACGGGGACGTCCGTGCTGCCTCTGGCTCCTGGGGGCAGTCCTTCTGATGGACGCGTCTGCACGGCCTGCCAACCACTCGTCCACTCGAG
AGAGAGTAGCCAACAGGGAGGAGAATGAGATCCTGCCCCCAGACCACCTGAACGGGGTGAAGCTGGAGATGGACGGGCACCTCAATCGCG
GCTTCCACCAGGAGGTCTTCCTAGGCAAGGACCTGGGTGGCTTTGATGAGGACGCGGAGCCGCGGCGGAGCCGGAGGAAGCTGATGGTCA

>41243_41243_2_KAT6B-SDF4_KAT6B_chr10_76788745_ENST00000372714_SDF4_chr1_1164117_ENST00000360001_length(amino acids)=1004AA_BP=
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYHHHE
RHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAE
RLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE
EEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVL
RKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRKKKRNQKSPRKKKTLHVWMITKRRRKRMKSHPTTRTMMPMTRMTATWSLPKWRRKSCP

--------------------------------------------------------------
>41243_41243_3_KAT6B-SDF4_KAT6B_chr10_76788745_ENST00000372714_SDF4_chr1_1164117_ENST00000545427_length(transcript)=5946nt_BP=5393nt
ACAAAATGGCGGCGGCTTAGCTCCTACCCCTGGCGGCGGCGGCAGCGGTGGCGGAGGCGACGGCACCTCCTCCAGGCGGCAGCCGCAGTT
TCTCAGGCAGCGGCAGCGCCCCCGGCAGGCGCGGTGGCGGTGGCGCGCAGCCAGGTCTTGATTTCCCAGTTAAAGATGTTCTTCACCCGA
ATGCAGTCTTTCCTGTTGGTAAAATAAGACAACCATCAACATTGCCTGTTTGTCTGCTTTTGAATCTCTTAAGGATGGATGTTTGTAAGA
TGTTGCTTAATACAGTCTGGAATACTCTGTCCATTTGTTGAATTGTAAATGACTTTCAAATGTGCAAGTTCTGTTAAATACAAAGAGAAC
CTCTATGGGTAACTTTTGTGTTGAAGAAGTCATTTGTCAACCATGGTAAAACTTGCAAACCCACTTTATACAGAGTGGATTCTTGAAGCT
ATACAGAAAATAAAAAAGCAAAAGCAAAGGCCCTCTGAAGAGAGAATCTGCCATGCGGTCAGTACTTCCCATGGGTTGGATAAGAAGACA
GTCTCTGAACAGCTGGAACTCAGTGTTCAGGATGGCTCAGTTCTCAAAGTCACCAACAAAGGCCTTGCCTCCTATAAGGACCCAGACAAC
CCTGGGCGCTTTTCATCAGTTAAACCAGGCACTTTTCCTAAGTCAGCCAAGGGGTCTAGAGGATCATGTAATGATCTCCGCAATGTGGAT
TGGAATAAACTTTTAAGGAGAGCAATTGAAGGACTTGAGGAGCCGAATGGCTCCTCCCTGAAGAACATAGAGAAGTATCTCAGAAGTCAA
AGTGATCTCACAAGCACCACCAACAACCCAGCCTTTCAGCAGCGGCTGCGACTGGGGGCCAAACGCGCTGTGAATAATGGGAGGTTACTG
AAAGACGGACCGCAGTACAGGGTCAATTATGGGAGCTTAGATGGCAAAGGGGCACCTCAGTATCCCAGTGCATTCCCATCCTCGCTCCCA
CCTGTCAGCCTTCTACCCCATGAGAAAGACCAGCCCCGTGCTGATCCCATTCCAATATGTAGCTTCTGTTTGGGGACTAAAGAATCAAAT
CGTGAAAAGAAACCAGAAGAACTCCTCTCTTGTGCAGATTGTGGCAGTAGTGGACACCCATCCTGTTTGAAATTTTGTCCTGAATTAACA
ACAAATGTAAAGGCCTTAAGGTGGCAGTGCATCGAATGCAAGACATGCAGTGCCTGTAGAGTCCAAGGCAGAAATGCTGATAATATGCTT
TTTTGTGATTCCTGTGATAGAGGATTTCATATGGAATGCTGTGACCCACCACTTTCCAGAATGCCAAAAGGGATGTGGATTTGCCAAGTC
TGCAGACCAAAGAAAAAGGGAAGAAAACTACTTCATGAGAAAGCTGCACAAATAAAACGACGATATGCAAAACCCATTGGACGACCGAAA
AATAAATTAAAGCAACGATTGTTGTCTGTAACCAGTGATGAAGGATCCATGAATGCATTCACAGGAAGGGGGTCACCTGATACTGAAATA
AAAATAAACATCAAACAAGAAAGTGCAGATGTAAATGTGATTGGAAACAAGGATGTCGTTACTGAAGAGGATTTGGATGTTTTTAAGCAG
GCCCAGGAACTTTCTTGGGAGAAAATAGAGTGTGAGAGTGGGGTGGAAGACTGTGGCCGGTACCCTTCTGTGATTGAATTTGGTAAATAT
GAAATCCAAACCTGGTACTCCTCGCCTTACCCACAGGAATATGCAAGATTACCAAAGCTTTACCTGTGTGAATTCTGTCTTAAATATATG
AAAAGTAAAAATATTTTGCTAAGACACTCCAAGAAGTGTGGATGGTTTCATCCTCCAGCAAATGAAATTTACCGAAGGAAAGACCTTTCA
GTATTTGAGGTTGATGGGAATATGAGCAAAATTTATTGCCAAAACCTTTGCTTGTTAGCCAAGCTCTTCCTGGACCACAAAACGTTGTAT
TATGATGTCGAGCCATTCCTTTTTTATGTCCTTACAAAAAATGATGAAAAGGGCTGTCATCTGGTTGGATACTTCTCTAAGGAAAAGCTT
TGCCAGCAGAAGTATAATGTCTCCTGCATAATGATCATGCCCCAGCACCAAAGGCAAGGATTTGGACGGTTTCTCATTGATTTCAGCTAT
TTGCTTTCTAGAAGAGAAGGCCAAGCAGGGTCTCCTGAAAAGCCTCTCTCCGATCTGGGCCGTCTCTCCTACCTGGCATATTGGAAGAGC
GTCATCTTGGAGTATCTCTACCACCACCATGAGAGGCACATCAGCATCAAGGCAATTAGCAGAGCGACGGGCATGTGCCCACATGACATT
GCCACCACTCTGCAGCACCTCCACATGATCGACAAGAGAGATGGCAGATTTGTCATCATTAGACGGGAAAAGTTGATATTGAGCCACATG
GAAAAGCTGAAAACCTGTTCCAGAGCCAATGAACTTGATCCAGACAGTCTGAGGTGGACCCCAATTTTAATTTCTAATGCTGCAGTGTCT
GAAGAAGAGCGAGAAGCTGAGAAAGAGGCTGAGCGGCTAATGGAACAAGCTAGCTGCTGGGAGAAGGAGGAACAAGAAATCCTGTCAACT
AGAGCTAACAGTAGGCAATCACCTGCAAAAGTACAATCGAAAAATAAATATTTGCATTCCCCGGAGAGCCGGCCAGTCACAGGGGAGCGA
GGGCAGCTGCTGGAGCTGTCTAAAGAGAGCAGTGAAGAAGAAGAGGAGGAGGAGGACGAGGAGGAGGAAGAAGAGGAGGAAGAAGAGGAA
GAGGATGAAGAGGAGGAAGAAGAGGAAGAAGAAGAAGAAGAAGAAGAAAATATTCAAAGCTCTCCCCCAAGATTGACGAAACCACAGTCA
GTTGCCATAAAGAGAAAGAGGCCTTTTGTACTAAAGAAGAAAAGGGGTCGTAAACGCAGGAGGATCAACAGCAGTGTAACAACAGAGACC
ATTTCAGAGACGACAGAAGTACTGAATGAGCCCTTTGACAACTCAGATGAAGAGAGGCCAATGCCACAGCTGGAGCCTACCTGTGAGATT
GAAGTGGAGGAAGATGGCAGGAAGCCAGTCCTGAGAAAAGCATTCCAGCATCAGCCTGGGAAGAAAAGACAAACAGAGGAAGAGGAAGGA
AAAGACAATCATTGCTTCAAGAATGCTGACCCTTGTAGAAAGAAAAAGAGGAACCAGAAATCTCCACGGAAAAAGAAGACTCTGCACGTT
TGGATGATCACGAAGAGGAGGAGGAAGAGGATGAAGAGCCATCCCACAACGAGGACCATGATGCCGATGACGAGGATGACAGCCACATGG
AGTCTGCCGAAGTGGAGAAGGAAGAGCTGCCCAGAGAAAGCTTCAAAGAAGTACTGGAAAACCAGGAGACTTTTTTAGACCTTAATGTGC
AGCCTGGTCACTCGAACCCAGAGGTCTTAATGGACTGTGGCGTCGACCTGACAGCTTCTTGTAACAGTGAGCCCAAGGAGCTTGCTGGGG
ACCCTGAAGCTGTACCCGAATCTGACGAGGAGCCACCCCCAGGAGAACAGGCACAGAAGCAGGACCAAAAGAACAGCAAGGAAGTCGATA
CAGAGTTCAAAGAGGGAAACCCAGCAACCATGGAAATCGACTCTGAGACTGTCCAGGCCGTTCAGTCTTTGACCCAGGAGAGCAGCGAAC
AGGACGACACCTTTCAGGATTGTGCCGAGACTCAAGAGGCCTGTAGAAGCCTACAGAACTACACCCGTGCAGACCAAAGTCCACAGATTG
CCACCACGCTCGACGATTGCCAACAGTCGGACCACAGTAGCCCAGTTTCATCCGTCCACTCCCATCCTGGCCAGTCCGTACGTTCTGTCA
ACAGCCCAAGTGTCCCTGCTCTGGAAAACAGCTACGCCCAAATCAGCCCAGATCAAAGTGCCATCTCAGTGCCATCTCTGCAGAACATGG
AAACCAGTCCCATGATGGATGTCCCATCAGTTTCAGATCATTCACAGCAAGTCGTAGACAGTGGATTTAGTGACCTGGGCAGTATCGAGA
GCACAACTGAGAACTACGAAAACCCAAGCAGCTACGATTCTACTATGGGAGGCAGCATCTGTGGAAACGGCTCTTCACAGAACAGCTGCT
CCTATAGCAACCTCACCTCCAGCAGTCTGACACAGAGCAGCTGTGCTGTCACCCAGCAGATGTCCAACATCAGCGGGAGCTGCAGCATGC
TGCAGCAAACCAGCATCAGCTCCCCTCCGACCTGCAGCGTCAAGTCTCCTCAAGGCTGTGTGGTGGAGAGGCCTCCGAGCAGCAGCCAGC
AGCTGGCTCAGTGCAGCATGGCTGCTAACTTCACCCCACCCATGCAGCTGGCTGAAATCCCCGAGACGAGCAACGCCAACATTGGCTTAT
ACGAGCGAATGGGTCAGAGTGATTTTGGGGCTGGGCATTACCCGCAGCCGTCAGCCACCTTCAGCCTTGCCAAACTGCAGCAGTTAACTA
ATACACTTATTGATCATTCATTGCCTTACAGCCATTCCGCTGCTGTGACTTCCTATGCAAACAGTGCCTCTTTGTCCACACCATTAAGTA
ACACAGGGCTTGTTCAACTTTCTCAGTCTCCACACTCCGTCCCTGGGGGACCCCAAGCACAAGCTACCATGACCCCACCCCCCAACCTGA
CTCCTCCTCCAATGAATCTGCCGCCGCCTCTTTTGCAACGGAACATGGCTGCATCAAATATTGGCATCTCTCACAGCCAAAGACTGCAAA
CCCAGATTGCCAGCAAGGGCCACATCTCCATGAGAACCAAGTCAGCGTCTCTGTCACCAGCCGCTGCCACCCATCAGTCACAAATCTATG
GGCGCTCCCAGACTGTAGCCATGCAGGGTCCTGCACGGACTTTAACGATGCAAAGAGGCATGAACATGAGTGTGAACCTGATGCCAGCGC
CAGCCTACAATGTCAACTCTGTGAACATGAACATGAACACTCTCAACGCCATGAATGGGTACAGCATGTCCCAGCCAATGATGAACAGTG
GCTACCACAGCAATCATGGCTATATGAATCAAACGCCCCAATACCCTATGCAGATGCAGATGGGCATGATGGGCACCCAGCCATATGCCC
AGCAGCCAATGCAGACCCCACCCCACGGTAACATGATGTACACGGCCCCCGGACATCACGGCTACATGAACACAGGCATGTCCAAACAGT
CTCTCAATGGCTCCTACATGAGAAGGTAGACAACGTGGGCAGTCCACAAAACCTACGGGGCATCACTATTGGATTGATCTGCACAAATAC
CTTTGAAGAGTACGATTTCAAAACCAGCAATTGGTGTGAATGCAAAAACATTTGTTGGCACCATTTATTTAAAAAAAAAAAAAGACATGG
CCCACCTGGACCTAGAGCTCTGTGAGTCACGTGTCTTGGGACGAGTATAAGGTGAAGTTTTTGGCGAGTAAAGGCCATAGCGAGAAGGAG
GTTGCCGACGCCATCAGGCTCAACGAGGAACTCAAAGTGGATGAGGAAAGGTGGATGTGAACACTGACCGGAAGATCAGTGCCAAGGAGA
TGCAGCGCTGGATCATGGAGAAGACGGCCGAGCACTTCCAGGAGGCCATGGAGGAGAGCAAGACACACTTCCGCGCCGTGGACCCTGACG
GGGACGTCCGTGCTGCCTCTGGCTCCTGGGGGCAGTCCTTCTGATGGACGCGTCTGCACGGCCTGCCAACCACTCGTCCACTCGAGAGAG
AGTAGCCAACAGGGAGGAGAATGAGATCCTGCCCCCAGACCACCTGAACGGGGTGAAGCTGGAGATGGACGGGCACCTCAATCGCGGCTT
CCACCAGGAGGTCTTCCTAGGCAAGGACCTGGGTGGCTTTGATGAGGACGCGGAGCCGCGGCGGAGCCGGAGGAAGCTGATGGTCATCTT

>41243_41243_3_KAT6B-SDF4_KAT6B_chr10_76788745_ENST00000372714_SDF4_chr1_1164117_ENST00000545427_length(amino acids)=1004AA_BP=
MSTMVKLANPLYTEWILEAIQKIKKQKQRPSEERICHAVSTSHGLDKKTVSEQLELSVQDGSVLKVTNKGLASYKDPDNPGRFSSVKPGT
FPKSAKGSRGSCNDLRNVDWNKLLRRAIEGLEEPNGSSLKNIEKYLRSQSDLTSTTNNPAFQQRLRLGAKRAVNNGRLLKDGPQYRVNYG
SLDGKGAPQYPSAFPSSLPPVSLLPHEKDQPRADPIPICSFCLGTKESNREKKPEELLSCADCGSSGHPSCLKFCPELTTNVKALRWQCI
ECKTCSACRVQGRNADNMLFCDSCDRGFHMECCDPPLSRMPKGMWICQVCRPKKKGRKLLHEKAAQIKRRYAKPIGRPKNKLKQRLLSVT
SDEGSMNAFTGRGSPDTEIKINIKQESADVNVIGNKDVVTEEDLDVFKQAQELSWEKIECESGVEDCGRYPSVIEFGKYEIQTWYSSPYP
QEYARLPKLYLCEFCLKYMKSKNILLRHSKKCGWFHPPANEIYRRKDLSVFEVDGNMSKIYCQNLCLLAKLFLDHKTLYYDVEPFLFYVL
TKNDEKGCHLVGYFSKEKLCQQKYNVSCIMIMPQHQRQGFGRFLIDFSYLLSRREGQAGSPEKPLSDLGRLSYLAYWKSVILEYLYHHHE
RHISIKAISRATGMCPHDIATTLQHLHMIDKRDGRFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAE
RLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEE
EEEEENIQSSPPRLTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEIEVEEDGRKPVL
RKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRKKKRNQKSPRKKKTLHVWMITKRRRKRMKSHPTTRTMMPMTRMTATWSLPKWRRKSCP

--------------------------------------------------------------

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Fusion Gene PPI Analysis for KAT6B-SDF4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+118752_100802074.0BRPF1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+117752_100801891.0BRPF1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+117752_100801782.0BRPF1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+118752_100801782.0BRPF1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+117752_100801782.0BRPF1
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000287239+1181560_207302074.0RUNX1 and RUNX2
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372711+1171560_207301891.0RUNX1 and RUNX2
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372714+1171560_207301782.0RUNX1 and RUNX2
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372724+1181560_207301782.0RUNX1 and RUNX2
HgeneKAT6Bchr10:76788745chr1:1164117ENST00000372725+1171560_207301782.0RUNX1 and RUNX2


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KAT6B-SDF4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KAT6B-SDF4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource