FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:KATNA1-PPP2R1A (FusionGDB2 ID:41258)

Fusion Gene Summary for KATNA1-PPP2R1A

check button Fusion gene summary
Fusion gene informationFusion gene name: KATNA1-PPP2R1A
Fusion gene ID: 41258
HgeneTgene
Gene symbol

KATNA1

PPP2R1A

Gene ID

11104

5518

Gene namekatanin catalytic subunit A1protein phosphatase 2 scaffold subunit Aalpha
Synonyms-MRD36|PP2A-Aalpha|PP2AA|PP2AAALPHA|PR65A
Cytomap

6q25.1

19q13.41

Type of geneprotein-codingprotein-coding
Descriptionkatanin p60 ATPase-containing subunit A1katanin p60 (ATPase containing) subunit A 1katanin p60 subunit A1p60 kataninserine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoformPP2A subunit A isoform PR65-alphaPP2A subunit A isoform R1-alphamedium tumor antigen-associated 61 KDA proteinprotein phosphatase 2 (formerly 2A), regulatory subunit A (P
Modification date2020031520200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000335643, ENST00000335647, 
ENST00000367411, ENST00000494504, 
ENST00000462990, ENST00000473455, 
ENST00000477989, ENST00000322088, 
ENST00000444322, 
Fusion gene scores* DoF score3 X 6 X 2=3610 X 12 X 4=480
# samples 412
** MAII scorelog2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(12/480*10)=-2
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KATNA1 [Title/Abstract] AND PPP2R1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKATNA1(149922730)-PPP2R1A(52719782), # samples:3
Anticipated loss of major functional domain due to fusion event.KATNA1-PPP2R1A seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
KATNA1-PPP2R1A seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF.
KATNA1-PPP2R1A seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
KATNA1-PPP2R1A seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePPP2R1A

GO:0007059

chromosome segregation

16580887


check buttonFusion gene breakpoints across KATNA1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PPP2R1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A08I-01AKATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
ChimerDB4BRCATCGA-A8-A08I-01AKATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
ChimerDB4BRCATCGA-A8-A08IKATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
ChimerDB4BRCATCGA-A8-A08IKATNA1chr6

149924403

-PPP2R1Achr19

52719781

+


Top

Fusion Gene ORF analysis for KATNA1-PPP2R1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000335643ENST00000462990KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000335643ENST00000462990KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000335643ENST00000473455KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000335643ENST00000473455KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000335643ENST00000477989KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000335643ENST00000477989KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000335647ENST00000462990KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000335647ENST00000462990KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000335647ENST00000462990KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000335647ENST00000462990KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000335647ENST00000473455KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000335647ENST00000473455KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000335647ENST00000473455KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000335647ENST00000473455KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000335647ENST00000477989KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000335647ENST00000477989KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000335647ENST00000477989KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000335647ENST00000477989KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000367411ENST00000462990KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000367411ENST00000462990KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000367411ENST00000462990KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000367411ENST00000462990KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000367411ENST00000473455KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000367411ENST00000473455KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000367411ENST00000473455KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000367411ENST00000473455KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000367411ENST00000477989KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000367411ENST00000477989KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5CDS-intronENST00000367411ENST00000477989KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5CDS-intronENST00000367411ENST00000477989KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5UTR-3CDSENST00000494504ENST00000322088KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5UTR-3CDSENST00000494504ENST00000322088KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5UTR-3CDSENST00000494504ENST00000322088KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5UTR-3CDSENST00000494504ENST00000322088KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5UTR-3CDSENST00000494504ENST00000444322KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5UTR-3CDSENST00000494504ENST00000444322KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5UTR-3CDSENST00000494504ENST00000444322KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5UTR-3CDSENST00000494504ENST00000444322KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5UTR-intronENST00000494504ENST00000462990KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5UTR-intronENST00000494504ENST00000462990KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5UTR-intronENST00000494504ENST00000462990KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5UTR-intronENST00000494504ENST00000462990KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5UTR-intronENST00000494504ENST00000473455KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5UTR-intronENST00000494504ENST00000473455KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5UTR-intronENST00000494504ENST00000473455KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5UTR-intronENST00000494504ENST00000473455KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
5UTR-intronENST00000494504ENST00000477989KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
5UTR-intronENST00000494504ENST00000477989KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
5UTR-intronENST00000494504ENST00000477989KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
5UTR-intronENST00000494504ENST00000477989KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
Frame-shiftENST00000335643ENST00000322088KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
Frame-shiftENST00000335643ENST00000322088KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
Frame-shiftENST00000335643ENST00000444322KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
Frame-shiftENST00000335643ENST00000444322KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
Frame-shiftENST00000367411ENST00000322088KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
Frame-shiftENST00000367411ENST00000322088KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
Frame-shiftENST00000367411ENST00000322088KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
Frame-shiftENST00000367411ENST00000322088KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
Frame-shiftENST00000367411ENST00000444322KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
Frame-shiftENST00000367411ENST00000444322KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
Frame-shiftENST00000367411ENST00000444322KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
Frame-shiftENST00000367411ENST00000444322KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
In-frameENST00000335647ENST00000322088KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
In-frameENST00000335647ENST00000322088KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
In-frameENST00000335647ENST00000322088KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
In-frameENST00000335647ENST00000322088KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
In-frameENST00000335647ENST00000444322KATNA1chr6

149922730

-PPP2R1Achr19

52719782

+
In-frameENST00000335647ENST00000444322KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
In-frameENST00000335647ENST00000444322KATNA1chr6

149922729

-PPP2R1Achr19

52719781

+
In-frameENST00000335647ENST00000444322KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
intron-3CDSENST00000335643ENST00000322088KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
intron-3CDSENST00000335643ENST00000322088KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
intron-3CDSENST00000335643ENST00000444322KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
intron-3CDSENST00000335643ENST00000444322KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
intron-intronENST00000335643ENST00000462990KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
intron-intronENST00000335643ENST00000462990KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
intron-intronENST00000335643ENST00000473455KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
intron-intronENST00000335643ENST00000473455KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+
intron-intronENST00000335643ENST00000477989KATNA1chr6

149924404

-PPP2R1Achr19

52719782

+
intron-intronENST00000335643ENST00000477989KATNA1chr6

149924403

-PPP2R1Achr19

52719781

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000335647KATNA1chr6149922730-ENST00000322088PPP2R1Achr1952719782+3163933391709556
ENST00000335647KATNA1chr6149922730-ENST00000444322PPP2R1Achr1952719782+1965933391709556
ENST00000335647KATNA1chr6149922729-ENST00000322088PPP2R1Achr1952719781+3163933391709556
ENST00000335647KATNA1chr6149922729-ENST00000444322PPP2R1Achr1952719781+1965933391709556
ENST00000335647KATNA1chr6149924403-ENST00000322088PPP2R1Achr1952719781+3004774391550503
ENST00000335647KATNA1chr6149924403-ENST00000444322PPP2R1Achr1952719781+1806774391550503
ENST00000335647KATNA1chr6149924404-ENST00000322088PPP2R1Achr1952719782+3004774391550503
ENST00000335647KATNA1chr6149924404-ENST00000444322PPP2R1Achr1952719782+1806774391550503

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000335647ENST00000322088KATNA1chr6149922730-PPP2R1Achr1952719782+0.0005375870.9994624
ENST00000335647ENST00000444322KATNA1chr6149922730-PPP2R1Achr1952719782+0.0009279820.99907196
ENST00000335647ENST00000322088KATNA1chr6149922729-PPP2R1Achr1952719781+0.0005375870.9994624
ENST00000335647ENST00000444322KATNA1chr6149922729-PPP2R1Achr1952719781+0.0009279820.99907196
ENST00000335647ENST00000322088KATNA1chr6149924403-PPP2R1Achr1952719781+0.0003945520.9996055
ENST00000335647ENST00000444322KATNA1chr6149924403-PPP2R1Achr1952719781+0.0006758040.9993242
ENST00000335647ENST00000322088KATNA1chr6149924404-PPP2R1Achr1952719782+0.0003945520.9996055
ENST00000335647ENST00000444322KATNA1chr6149924404-PPP2R1Achr1952719782+0.0006758040.9993242

Top

Fusion Genomic Features for KATNA1-PPP2R1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KATNA1chr6149922729-PPP2R1Achr1952719781+3.27E-131
KATNA1chr6149922729-PPP2R1Achr1952719781+3.27E-131
KATNA1chr6149924403-PPP2R1Achr1952719781+1.19E-111
KATNA1chr6149924403-PPP2R1Achr1952719781+1.19E-111
KATNA1chr6149922729-PPP2R1Achr1952719781+3.27E-131
KATNA1chr6149922729-PPP2R1Achr1952719781+3.27E-131
KATNA1chr6149924403-PPP2R1Achr1952719781+1.19E-111
KATNA1chr6149924403-PPP2R1Achr1952719781+1.19E-111

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for KATNA1-PPP2R1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr6:149922730/chr19:52719782)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKATNA1chr6:149922729chr19:52719781ENST00000335647-610249_256296492.0Nucleotide bindingATP
HgeneKATNA1chr6:149922729chr19:52719781ENST00000367411-711249_256296492.0Nucleotide bindingATP
HgeneKATNA1chr6:149922730chr19:52719782ENST00000335647-610249_256296492.0Nucleotide bindingATP
HgeneKATNA1chr6:149922730chr19:52719782ENST00000367411-711249_256296492.0Nucleotide bindingATP
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715400_589331590.0RegionNote=PP2A subunit C binding
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715400_589331590.0RegionNote=PP2A subunit C binding
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715400_589331590.0RegionNote=PP2A subunit C binding
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715400_589331590.0RegionNote=PP2A subunit C binding
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715361_399331590.0RepeatNote=HEAT 10
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715400_438331590.0RepeatNote=HEAT 11
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715439_477331590.0RepeatNote=HEAT 12
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715478_516331590.0RepeatNote=HEAT 13
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715517_555331590.0RepeatNote=HEAT 14
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715556_589331590.0RepeatNote=HEAT 15
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715361_399331590.0RepeatNote=HEAT 10
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715400_438331590.0RepeatNote=HEAT 11
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715439_477331590.0RepeatNote=HEAT 12
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715478_516331590.0RepeatNote=HEAT 13
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715517_555331590.0RepeatNote=HEAT 14
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715556_589331590.0RepeatNote=HEAT 15
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715361_399331590.0RepeatNote=HEAT 10
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715400_438331590.0RepeatNote=HEAT 11
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715439_477331590.0RepeatNote=HEAT 12
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715478_516331590.0RepeatNote=HEAT 13
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715517_555331590.0RepeatNote=HEAT 14
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715556_589331590.0RepeatNote=HEAT 15
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715361_399331590.0RepeatNote=HEAT 10
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715400_438331590.0RepeatNote=HEAT 11
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715439_477331590.0RepeatNote=HEAT 12
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715478_516331590.0RepeatNote=HEAT 13
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715517_555331590.0RepeatNote=HEAT 14
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715556_589331590.0RepeatNote=HEAT 15

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKATNA1chr6:149922729chr19:52719781ENST00000335643-58249_256220312.0Nucleotide bindingATP
HgeneKATNA1chr6:149922730chr19:52719782ENST00000335643-58249_256220312.0Nucleotide bindingATP
HgeneKATNA1chr6:149924403chr19:52719781ENST00000335643-18249_2560312.0Nucleotide bindingATP
HgeneKATNA1chr6:149924403chr19:52719781ENST00000335647-510249_256243492.0Nucleotide bindingATP
HgeneKATNA1chr6:149924403chr19:52719781ENST00000367411-611249_256243492.0Nucleotide bindingATP
HgeneKATNA1chr6:149924404chr19:52719782ENST00000335643-18249_2560312.0Nucleotide bindingATP
HgeneKATNA1chr6:149924404chr19:52719782ENST00000335647-510249_256243492.0Nucleotide bindingATP
HgeneKATNA1chr6:149924404chr19:52719782ENST00000367411-611249_256243492.0Nucleotide bindingATP
TgenePPP2R1Achr6:149922729chr19:52719781ENST0000032208871547_321331590.0RegionNote=Polyoma small and medium T antigens Binding
TgenePPP2R1Achr6:149922729chr19:52719781ENST0000032208871585_239331590.0RegionNote=SV40 small T antigen binding
TgenePPP2R1Achr6:149922729chr19:52719781ENST000003220887158_399331590.0RegionNote=PP2A subunit B binding
TgenePPP2R1Achr6:149922730chr19:52719782ENST0000032208871547_321331590.0RegionNote=Polyoma small and medium T antigens Binding
TgenePPP2R1Achr6:149922730chr19:52719782ENST0000032208871585_239331590.0RegionNote=SV40 small T antigen binding
TgenePPP2R1Achr6:149922730chr19:52719782ENST000003220887158_399331590.0RegionNote=PP2A subunit B binding
TgenePPP2R1Achr6:149924403chr19:52719781ENST0000032208871547_321331590.0RegionNote=Polyoma small and medium T antigens Binding
TgenePPP2R1Achr6:149924403chr19:52719781ENST0000032208871585_239331590.0RegionNote=SV40 small T antigen binding
TgenePPP2R1Achr6:149924403chr19:52719781ENST000003220887158_399331590.0RegionNote=PP2A subunit B binding
TgenePPP2R1Achr6:149924404chr19:52719782ENST0000032208871547_321331590.0RegionNote=Polyoma small and medium T antigens Binding
TgenePPP2R1Achr6:149924404chr19:52719782ENST0000032208871585_239331590.0RegionNote=SV40 small T antigen binding
TgenePPP2R1Achr6:149924404chr19:52719782ENST000003220887158_399331590.0RegionNote=PP2A subunit B binding
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715124_161331590.0RepeatNote=HEAT 4
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715162_200331590.0RepeatNote=HEAT 5
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715201_239331590.0RepeatNote=HEAT 6
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715240_278331590.0RepeatNote=HEAT 7
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715279_321331590.0RepeatNote=HEAT 8
TgenePPP2R1Achr6:149922729chr19:52719781ENST00000322088715322_360331590.0RepeatNote=HEAT 9
TgenePPP2R1Achr6:149922729chr19:52719781ENST0000032208871547_84331590.0RepeatNote=HEAT 2
TgenePPP2R1Achr6:149922729chr19:52719781ENST0000032208871585_123331590.0RepeatNote=HEAT 3
TgenePPP2R1Achr6:149922729chr19:52719781ENST000003220887158_46331590.0RepeatNote=HEAT 1
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715124_161331590.0RepeatNote=HEAT 4
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715162_200331590.0RepeatNote=HEAT 5
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715201_239331590.0RepeatNote=HEAT 6
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715240_278331590.0RepeatNote=HEAT 7
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715279_321331590.0RepeatNote=HEAT 8
TgenePPP2R1Achr6:149922730chr19:52719782ENST00000322088715322_360331590.0RepeatNote=HEAT 9
TgenePPP2R1Achr6:149922730chr19:52719782ENST0000032208871547_84331590.0RepeatNote=HEAT 2
TgenePPP2R1Achr6:149922730chr19:52719782ENST0000032208871585_123331590.0RepeatNote=HEAT 3
TgenePPP2R1Achr6:149922730chr19:52719782ENST000003220887158_46331590.0RepeatNote=HEAT 1
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715124_161331590.0RepeatNote=HEAT 4
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715162_200331590.0RepeatNote=HEAT 5
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715201_239331590.0RepeatNote=HEAT 6
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715240_278331590.0RepeatNote=HEAT 7
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715279_321331590.0RepeatNote=HEAT 8
TgenePPP2R1Achr6:149924403chr19:52719781ENST00000322088715322_360331590.0RepeatNote=HEAT 9
TgenePPP2R1Achr6:149924403chr19:52719781ENST0000032208871547_84331590.0RepeatNote=HEAT 2
TgenePPP2R1Achr6:149924403chr19:52719781ENST0000032208871585_123331590.0RepeatNote=HEAT 3
TgenePPP2R1Achr6:149924403chr19:52719781ENST000003220887158_46331590.0RepeatNote=HEAT 1
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715124_161331590.0RepeatNote=HEAT 4
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715162_200331590.0RepeatNote=HEAT 5
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715201_239331590.0RepeatNote=HEAT 6
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715240_278331590.0RepeatNote=HEAT 7
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715279_321331590.0RepeatNote=HEAT 8
TgenePPP2R1Achr6:149924404chr19:52719782ENST00000322088715322_360331590.0RepeatNote=HEAT 9
TgenePPP2R1Achr6:149924404chr19:52719782ENST0000032208871547_84331590.0RepeatNote=HEAT 2
TgenePPP2R1Achr6:149924404chr19:52719782ENST0000032208871585_123331590.0RepeatNote=HEAT 3
TgenePPP2R1Achr6:149924404chr19:52719782ENST000003220887158_46331590.0RepeatNote=HEAT 1


Top

Fusion Gene Sequence for KATNA1-PPP2R1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>41258_41258_1_KATNA1-PPP2R1A_KATNA1_chr6_149922729_ENST00000335647_PPP2R1A_chr19_52719781_ENST00000322088_length(transcript)=3163nt_BP=933nt
TAAAGTGTTTCTTTTTTTCTTCTTCTTTTTAGCTTACAGTTGAACATGAGTCTTCTTATGATTAGTGAGAATGTAAAATTGGCTCGTGAA
TATGCATTGCTGGGAAACTATGACTCTGCGATGGTCTATTATCAGGGAGTTCTTGACCAAATGAACAAGTATCTGTACTCAGTCAAAGAT
ACATACCTCCAGCAGAAATGGCAACAGGTTTGGCAGGAAATAAATGTGGAAGCTAAACATGTTAAAGATATCATGAAAACACTAGAGAGC
TTTAAACTGGACAGCACTCCCTTGAAAGCGGCACAGCATGACCTTCCAGCTTCTGAGGGAGAAGTCTGGTCCATGCCTGTACCTGTTGAA
CGAAGACCCTCACCAGGACCTAGAAAACGCCAATCTTCTCAGTACAGTGACCCTAAATCACATGGTAATCGTCCAAGTACAACTGTCAGA
GTTCACCGTTCATCTGCACAGAATGTTCACAATGACAGAGGGAAAGCTGTTCGTTGTCGTGAAAAGAAAGAACAGAATAAAGGAAGAGAG
GAAAAGAACAAATCACCTGCTGCAGTAACAGAACCAGAGACAAATAAATTTGATAGTACCGGATATGATAAAGACTTAGTAGAAGCTTTG
GAAAGAGATATAATTTCCCAGAATCCCAATGTTCGATGGGATGATATCGCTGATTTAGTAGAAGCTAAAAAGTTGCTTAAGGAAGCCGTA
GTGTTACCAATGTGGATGCCCGAATTCTTTAAGGGCATTAGGAGACCATGGAAAGGAGTACTGATGGTCGGCCCACCTGGCACGGGGAAG
ACGCTCCTTGCTAAAGCAGTAGCTACAGAATGCAAGACAACATTCTTCAATGTCTCTTCATCAACTTTGACTTCCAAATACAGAGGAGAA
TCTGAGAAGCTTGTTCGTCTTCTGTTTGAAATGGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCTGCCCTGGCCTCAGTCATCATG
GGTCTCTCTCCCATCTTGGGCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTGAAGGATGAGTGCCCTGAGGTA
CGGCTGAACATCATCTCTAACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCCCTGCTCCCTGCCATTGTGGAG
CTGGCTGAGGACGCCAAGTGGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAGCTGGGAGTGGAGTTCTTTGAT
GAGAAACTTAACTCCTTGTGCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACCAGCAACCTGAAGAAGCTAGTG
GAAAAGTTTGGGAAGGAGTGGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCCAACTACCTGCACCGCATGACT
ACGCTCTTCTGCATCAATGTGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCCACGGTTCTGCGCATGGCTGGG
GACCCGGTTGCCAATGTCCGCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAACAGCACCTTGCAGAGTGAAGTC
AAGCCCATCCTAGAGAAGCTGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTGACTGTTCTGTCTCTCGCCTGA
TGCTGGAAGAGGAGCAAACACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGAGACACTGGGGGGCCTTTGGCT
GTCACTCCCTGTGCATGGTCTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGGGAAGATGTCTCACTGTCCACC
TCCCAACGGGCTAGGGGAGCACGGGGTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCCACGTCAGGGAGAGATGTGAGC
ATCCCGGGTCACTGGATCCTGCTGCTGTAATGGGAACCCCTCCCCCATTTACTTCTCCACCTCCCGTCCTCCCCATCATTGGTTTTTTTT
TGTGTGTCAACTGTGCCGTTTTTATTTTATTCCTTTTATTTTCCCCCTTTTCACAGAGAAATAAAGGTCTAGAAGTAGTTGGTCCTCTGG
CCTTAGTCATCAGCTTGGAGGAGGGGGCACCACCCCAGAGCCACAACATCTGCGCTTTTCTCTGGAGAAGATCTTGTTACAGGACCCATT
ATACCCCTATGTCCCGAAAGAATACTCTGGGGATCCCCCCAGGAGTGCTGCTGGCCTTTGGGGTAGAGGGTCCATGAGGTGCTCTGGGTG
GTGTCCTGTAGTGCAGTTCAGATTCATAGATGTCGGCCGAGTATTTGGGGGGTTAAGAGCAGGTGCCTTGGAACCAGACTGCCTGGGTCC
AAATTGTGGCTCCTTCAGTTAATAGACGTGTGACTAGGAGTAGCTTGTTAAGTCTTTATGAGCTCAGTTTTGTATTGTGTAAAATGAGAG
TTACAGTAATACCTAGATTGCAGGGTGGGTGGCGAGGACCAAGTGAATTAGTACCTGGAAAGTGTGTAACAGTTTCAACATGAGAAGTAC
ACAACATGAGAAGCAGAGTTAGCTGTACATTGCCAGAGAACCCCCTGTGGGCCATTTCCTGTGTTCTTGAAGAAGACTTGGGCTTGGACC
CTGTCCCCAGGAGGTCTCAGAGTAATCAGGACGGTACTAGGGAGAGAACTGTGGCAAGATAGATCAGTTATCTCGGTATCTATTCTCCCC
TTCCTAATGTAGAAGCTCTGATTTTTAACTGGGCAGATGACTACATGGATTCAAGGTATTTTCCTAGTGTCTCTTGAAATTAGGTGTGGT
ATTGTGACCAAATTCTAGCCAAAAAGATGTTGAACAGAAGTGGTATATGCAGCTTCTAGGAAGTGTTCTTAAGGGGGAAGGCGTCATCCC
CCACCTTTCCTCCTTCCTGCACTCTGGAATGTGGACCAGATGGCTGGAGTAGGAGCTGCCACCTGGGGCCAGAAAATGATCTTAGGCGTG
AAGGTCAAGTAAGGCAGGACAAGAGAGAAGGAGCCTGCCTCCCCGAGGCTGTGAAGAGCCATGCCAGTACTGTCACCTGGGAGAATTAAA

>41258_41258_1_KATNA1-PPP2R1A_KATNA1_chr6_149922729_ENST00000335647_PPP2R1A_chr19_52719781_ENST00000322088_length(amino acids)=556AA_BP=298
MNMSLLMISENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSVKDTYLQQKWQQVWQEINVEAKHVKDIMKTLESFKLDSTPLKAAQH
DLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHNDRGKAVRCREKKEQNKGREEKNKSPAAVTEPE
TNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKT
TFFNVSSSTLTSKYRGESEKLVRLLFEMELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNE
VIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATII
PKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDV

--------------------------------------------------------------
>41258_41258_2_KATNA1-PPP2R1A_KATNA1_chr6_149922729_ENST00000335647_PPP2R1A_chr19_52719781_ENST00000444322_length(transcript)=1965nt_BP=933nt
TAAAGTGTTTCTTTTTTTCTTCTTCTTTTTAGCTTACAGTTGAACATGAGTCTTCTTATGATTAGTGAGAATGTAAAATTGGCTCGTGAA
TATGCATTGCTGGGAAACTATGACTCTGCGATGGTCTATTATCAGGGAGTTCTTGACCAAATGAACAAGTATCTGTACTCAGTCAAAGAT
ACATACCTCCAGCAGAAATGGCAACAGGTTTGGCAGGAAATAAATGTGGAAGCTAAACATGTTAAAGATATCATGAAAACACTAGAGAGC
TTTAAACTGGACAGCACTCCCTTGAAAGCGGCACAGCATGACCTTCCAGCTTCTGAGGGAGAAGTCTGGTCCATGCCTGTACCTGTTGAA
CGAAGACCCTCACCAGGACCTAGAAAACGCCAATCTTCTCAGTACAGTGACCCTAAATCACATGGTAATCGTCCAAGTACAACTGTCAGA
GTTCACCGTTCATCTGCACAGAATGTTCACAATGACAGAGGGAAAGCTGTTCGTTGTCGTGAAAAGAAAGAACAGAATAAAGGAAGAGAG
GAAAAGAACAAATCACCTGCTGCAGTAACAGAACCAGAGACAAATAAATTTGATAGTACCGGATATGATAAAGACTTAGTAGAAGCTTTG
GAAAGAGATATAATTTCCCAGAATCCCAATGTTCGATGGGATGATATCGCTGATTTAGTAGAAGCTAAAAAGTTGCTTAAGGAAGCCGTA
GTGTTACCAATGTGGATGCCCGAATTCTTTAAGGGCATTAGGAGACCATGGAAAGGAGTACTGATGGTCGGCCCACCTGGCACGGGGAAG
ACGCTCCTTGCTAAAGCAGTAGCTACAGAATGCAAGACAACATTCTTCAATGTCTCTTCATCAACTTTGACTTCCAAATACAGAGGAGAA
TCTGAGAAGCTTGTTCGTCTTCTGTTTGAAATGGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCTGCCCTGGCCTCAGTCATCATG
GGTCTCTCTCCCATCTTGGGCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTGAAGGATGAGTGCCCTGAGGTA
CGGCTGAACATCATCTCTAACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCCCTGCTCCCTGCCATTGTGGAG
CTGGCTGAGGACGCCAAGTGGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAGCTGGGAGTGGAGTTCTTTGAT
GAGAAACTTAACTCCTTGTGCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACCAGCAACCTGAAGAAGCTAGTG
GAAAAGTTTGGGAAGGAGTGGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCCAACTACCTGCACCGCATGACT
ACGCTCTTCTGCATCAATGTGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCCACGGTTCTGCGCATGGCTGGG
GACCCGGTTGCCAATGTCCGCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAACAGCACCTTGCAGAGTGAAGTC
AAGCCCATCCTAGAGAAGCTGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTGACTGTTCTGTCTCTCGCCTGA
TGCTGGAAGAGGAGCAAACACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGAGACACTGGGGGGCCTTTGGCT
GTCACTCCCTGTGCATGGTCTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGGGAAGATGTCTCACTGTCCACC

>41258_41258_2_KATNA1-PPP2R1A_KATNA1_chr6_149922729_ENST00000335647_PPP2R1A_chr19_52719781_ENST00000444322_length(amino acids)=556AA_BP=298
MNMSLLMISENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSVKDTYLQQKWQQVWQEINVEAKHVKDIMKTLESFKLDSTPLKAAQH
DLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHNDRGKAVRCREKKEQNKGREEKNKSPAAVTEPE
TNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKT
TFFNVSSSTLTSKYRGESEKLVRLLFEMELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNE
VIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATII
PKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDV

--------------------------------------------------------------
>41258_41258_3_KATNA1-PPP2R1A_KATNA1_chr6_149922730_ENST00000335647_PPP2R1A_chr19_52719782_ENST00000322088_length(transcript)=3163nt_BP=933nt
TAAAGTGTTTCTTTTTTTCTTCTTCTTTTTAGCTTACAGTTGAACATGAGTCTTCTTATGATTAGTGAGAATGTAAAATTGGCTCGTGAA
TATGCATTGCTGGGAAACTATGACTCTGCGATGGTCTATTATCAGGGAGTTCTTGACCAAATGAACAAGTATCTGTACTCAGTCAAAGAT
ACATACCTCCAGCAGAAATGGCAACAGGTTTGGCAGGAAATAAATGTGGAAGCTAAACATGTTAAAGATATCATGAAAACACTAGAGAGC
TTTAAACTGGACAGCACTCCCTTGAAAGCGGCACAGCATGACCTTCCAGCTTCTGAGGGAGAAGTCTGGTCCATGCCTGTACCTGTTGAA
CGAAGACCCTCACCAGGACCTAGAAAACGCCAATCTTCTCAGTACAGTGACCCTAAATCACATGGTAATCGTCCAAGTACAACTGTCAGA
GTTCACCGTTCATCTGCACAGAATGTTCACAATGACAGAGGGAAAGCTGTTCGTTGTCGTGAAAAGAAAGAACAGAATAAAGGAAGAGAG
GAAAAGAACAAATCACCTGCTGCAGTAACAGAACCAGAGACAAATAAATTTGATAGTACCGGATATGATAAAGACTTAGTAGAAGCTTTG
GAAAGAGATATAATTTCCCAGAATCCCAATGTTCGATGGGATGATATCGCTGATTTAGTAGAAGCTAAAAAGTTGCTTAAGGAAGCCGTA
GTGTTACCAATGTGGATGCCCGAATTCTTTAAGGGCATTAGGAGACCATGGAAAGGAGTACTGATGGTCGGCCCACCTGGCACGGGGAAG
ACGCTCCTTGCTAAAGCAGTAGCTACAGAATGCAAGACAACATTCTTCAATGTCTCTTCATCAACTTTGACTTCCAAATACAGAGGAGAA
TCTGAGAAGCTTGTTCGTCTTCTGTTTGAAATGGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCTGCCCTGGCCTCAGTCATCATG
GGTCTCTCTCCCATCTTGGGCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTGAAGGATGAGTGCCCTGAGGTA
CGGCTGAACATCATCTCTAACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCCCTGCTCCCTGCCATTGTGGAG
CTGGCTGAGGACGCCAAGTGGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAGCTGGGAGTGGAGTTCTTTGAT
GAGAAACTTAACTCCTTGTGCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACCAGCAACCTGAAGAAGCTAGTG
GAAAAGTTTGGGAAGGAGTGGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCCAACTACCTGCACCGCATGACT
ACGCTCTTCTGCATCAATGTGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCCACGGTTCTGCGCATGGCTGGG
GACCCGGTTGCCAATGTCCGCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAACAGCACCTTGCAGAGTGAAGTC
AAGCCCATCCTAGAGAAGCTGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTGACTGTTCTGTCTCTCGCCTGA
TGCTGGAAGAGGAGCAAACACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGAGACACTGGGGGGCCTTTGGCT
GTCACTCCCTGTGCATGGTCTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGGGAAGATGTCTCACTGTCCACC
TCCCAACGGGCTAGGGGAGCACGGGGTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCCACGTCAGGGAGAGATGTGAGC
ATCCCGGGTCACTGGATCCTGCTGCTGTAATGGGAACCCCTCCCCCATTTACTTCTCCACCTCCCGTCCTCCCCATCATTGGTTTTTTTT
TGTGTGTCAACTGTGCCGTTTTTATTTTATTCCTTTTATTTTCCCCCTTTTCACAGAGAAATAAAGGTCTAGAAGTAGTTGGTCCTCTGG
CCTTAGTCATCAGCTTGGAGGAGGGGGCACCACCCCAGAGCCACAACATCTGCGCTTTTCTCTGGAGAAGATCTTGTTACAGGACCCATT
ATACCCCTATGTCCCGAAAGAATACTCTGGGGATCCCCCCAGGAGTGCTGCTGGCCTTTGGGGTAGAGGGTCCATGAGGTGCTCTGGGTG
GTGTCCTGTAGTGCAGTTCAGATTCATAGATGTCGGCCGAGTATTTGGGGGGTTAAGAGCAGGTGCCTTGGAACCAGACTGCCTGGGTCC
AAATTGTGGCTCCTTCAGTTAATAGACGTGTGACTAGGAGTAGCTTGTTAAGTCTTTATGAGCTCAGTTTTGTATTGTGTAAAATGAGAG
TTACAGTAATACCTAGATTGCAGGGTGGGTGGCGAGGACCAAGTGAATTAGTACCTGGAAAGTGTGTAACAGTTTCAACATGAGAAGTAC
ACAACATGAGAAGCAGAGTTAGCTGTACATTGCCAGAGAACCCCCTGTGGGCCATTTCCTGTGTTCTTGAAGAAGACTTGGGCTTGGACC
CTGTCCCCAGGAGGTCTCAGAGTAATCAGGACGGTACTAGGGAGAGAACTGTGGCAAGATAGATCAGTTATCTCGGTATCTATTCTCCCC
TTCCTAATGTAGAAGCTCTGATTTTTAACTGGGCAGATGACTACATGGATTCAAGGTATTTTCCTAGTGTCTCTTGAAATTAGGTGTGGT
ATTGTGACCAAATTCTAGCCAAAAAGATGTTGAACAGAAGTGGTATATGCAGCTTCTAGGAAGTGTTCTTAAGGGGGAAGGCGTCATCCC
CCACCTTTCCTCCTTCCTGCACTCTGGAATGTGGACCAGATGGCTGGAGTAGGAGCTGCCACCTGGGGCCAGAAAATGATCTTAGGCGTG
AAGGTCAAGTAAGGCAGGACAAGAGAGAAGGAGCCTGCCTCCCCGAGGCTGTGAAGAGCCATGCCAGTACTGTCACCTGGGAGAATTAAA

>41258_41258_3_KATNA1-PPP2R1A_KATNA1_chr6_149922730_ENST00000335647_PPP2R1A_chr19_52719782_ENST00000322088_length(amino acids)=556AA_BP=298
MNMSLLMISENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSVKDTYLQQKWQQVWQEINVEAKHVKDIMKTLESFKLDSTPLKAAQH
DLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHNDRGKAVRCREKKEQNKGREEKNKSPAAVTEPE
TNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKT
TFFNVSSSTLTSKYRGESEKLVRLLFEMELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNE
VIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATII
PKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDV

--------------------------------------------------------------
>41258_41258_4_KATNA1-PPP2R1A_KATNA1_chr6_149922730_ENST00000335647_PPP2R1A_chr19_52719782_ENST00000444322_length(transcript)=1965nt_BP=933nt
TAAAGTGTTTCTTTTTTTCTTCTTCTTTTTAGCTTACAGTTGAACATGAGTCTTCTTATGATTAGTGAGAATGTAAAATTGGCTCGTGAA
TATGCATTGCTGGGAAACTATGACTCTGCGATGGTCTATTATCAGGGAGTTCTTGACCAAATGAACAAGTATCTGTACTCAGTCAAAGAT
ACATACCTCCAGCAGAAATGGCAACAGGTTTGGCAGGAAATAAATGTGGAAGCTAAACATGTTAAAGATATCATGAAAACACTAGAGAGC
TTTAAACTGGACAGCACTCCCTTGAAAGCGGCACAGCATGACCTTCCAGCTTCTGAGGGAGAAGTCTGGTCCATGCCTGTACCTGTTGAA
CGAAGACCCTCACCAGGACCTAGAAAACGCCAATCTTCTCAGTACAGTGACCCTAAATCACATGGTAATCGTCCAAGTACAACTGTCAGA
GTTCACCGTTCATCTGCACAGAATGTTCACAATGACAGAGGGAAAGCTGTTCGTTGTCGTGAAAAGAAAGAACAGAATAAAGGAAGAGAG
GAAAAGAACAAATCACCTGCTGCAGTAACAGAACCAGAGACAAATAAATTTGATAGTACCGGATATGATAAAGACTTAGTAGAAGCTTTG
GAAAGAGATATAATTTCCCAGAATCCCAATGTTCGATGGGATGATATCGCTGATTTAGTAGAAGCTAAAAAGTTGCTTAAGGAAGCCGTA
GTGTTACCAATGTGGATGCCCGAATTCTTTAAGGGCATTAGGAGACCATGGAAAGGAGTACTGATGGTCGGCCCACCTGGCACGGGGAAG
ACGCTCCTTGCTAAAGCAGTAGCTACAGAATGCAAGACAACATTCTTCAATGTCTCTTCATCAACTTTGACTTCCAAATACAGAGGAGAA
TCTGAGAAGCTTGTTCGTCTTCTGTTTGAAATGGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCTGCCCTGGCCTCAGTCATCATG
GGTCTCTCTCCCATCTTGGGCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTGAAGGATGAGTGCCCTGAGGTA
CGGCTGAACATCATCTCTAACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCCCTGCTCCCTGCCATTGTGGAG
CTGGCTGAGGACGCCAAGTGGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAGCTGGGAGTGGAGTTCTTTGAT
GAGAAACTTAACTCCTTGTGCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACCAGCAACCTGAAGAAGCTAGTG
GAAAAGTTTGGGAAGGAGTGGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCCAACTACCTGCACCGCATGACT
ACGCTCTTCTGCATCAATGTGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCCACGGTTCTGCGCATGGCTGGG
GACCCGGTTGCCAATGTCCGCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAACAGCACCTTGCAGAGTGAAGTC
AAGCCCATCCTAGAGAAGCTGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTGACTGTTCTGTCTCTCGCCTGA
TGCTGGAAGAGGAGCAAACACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGAGACACTGGGGGGCCTTTGGCT
GTCACTCCCTGTGCATGGTCTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGGGAAGATGTCTCACTGTCCACC

>41258_41258_4_KATNA1-PPP2R1A_KATNA1_chr6_149922730_ENST00000335647_PPP2R1A_chr19_52719782_ENST00000444322_length(amino acids)=556AA_BP=298
MNMSLLMISENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSVKDTYLQQKWQQVWQEINVEAKHVKDIMKTLESFKLDSTPLKAAQH
DLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHNDRGKAVRCREKKEQNKGREEKNKSPAAVTEPE
TNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPWKGVLMVGPPGTGKTLLAKAVATECKT
TFFNVSSSTLTSKYRGESEKLVRLLFEMELVSDANQHVKSALASVIMGLSPILGKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNE
VIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSLCMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATII
PKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANVRFNVAKSLQKIGPILDNSTLQSEVKPILEKLTQDQDV

--------------------------------------------------------------
>41258_41258_5_KATNA1-PPP2R1A_KATNA1_chr6_149924403_ENST00000335647_PPP2R1A_chr19_52719781_ENST00000322088_length(transcript)=3004nt_BP=774nt
TAAAGTGTTTCTTTTTTTCTTCTTCTTTTTAGCTTACAGTTGAACATGAGTCTTCTTATGATTAGTGAGAATGTAAAATTGGCTCGTGAA
TATGCATTGCTGGGAAACTATGACTCTGCGATGGTCTATTATCAGGGAGTTCTTGACCAAATGAACAAGTATCTGTACTCAGTCAAAGAT
ACATACCTCCAGCAGAAATGGCAACAGGTTTGGCAGGAAATAAATGTGGAAGCTAAACATGTTAAAGATATCATGAAAACACTAGAGAGC
TTTAAACTGGACAGCACTCCCTTGAAAGCGGCACAGCATGACCTTCCAGCTTCTGAGGGAGAAGTCTGGTCCATGCCTGTACCTGTTGAA
CGAAGACCCTCACCAGGACCTAGAAAACGCCAATCTTCTCAGTACAGTGACCCTAAATCACATGGTAATCGTCCAAGTACAACTGTCAGA
GTTCACCGTTCATCTGCACAGAATGTTCACAATGACAGAGGGAAAGCTGTTCGTTGTCGTGAAAAGAAAGAACAGAATAAAGGAAGAGAG
GAAAAGAACAAATCACCTGCTGCAGTAACAGAACCAGAGACAAATAAATTTGATAGTACCGGATATGATAAAGACTTAGTAGAAGCTTTG
GAAAGAGATATAATTTCCCAGAATCCCAATGTTCGATGGGATGATATCGCTGATTTAGTAGAAGCTAAAAAGTTGCTTAAGGAAGCCGTA
GTGTTACCAATGTGGATGCCCGAATTCTTTAAGGGCATTAGGAGACCATGGAAAGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCT
GCCCTGGCCTCAGTCATCATGGGTCTCTCTCCCATCTTGGGCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTG
AAGGATGAGTGCCCTGAGGTACGGCTGAACATCATCTCTAACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCC
CTGCTCCCTGCCATTGTGGAGCTGGCTGAGGACGCCAAGTGGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAG
CTGGGAGTGGAGTTCTTTGATGAGAAACTTAACTCCTTGTGCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACC
AGCAACCTGAAGAAGCTAGTGGAAAAGTTTGGGAAGGAGTGGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCC
AACTACCTGCACCGCATGACTACGCTCTTCTGCATCAATGTGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCC
ACGGTTCTGCGCATGGCTGGGGACCCGGTTGCCAATGTCCGCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAAC
AGCACCTTGCAGAGTGAAGTCAAGCCCATCCTAGAGAAGCTGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTG
ACTGTTCTGTCTCTCGCCTGATGCTGGAAGAGGAGCAAACACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGA
GACACTGGGGGGCCTTTGGCTGTCACTCCCTGTGCATGGTCTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGG
GAAGATGTCTCACTGTCCACCTCCCAACGGGCTAGGGGAGCACGGGGTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCC
ACGTCAGGGAGAGATGTGAGCATCCCGGGTCACTGGATCCTGCTGCTGTAATGGGAACCCCTCCCCCATTTACTTCTCCACCTCCCGTCC
TCCCCATCATTGGTTTTTTTTTGTGTGTCAACTGTGCCGTTTTTATTTTATTCCTTTTATTTTCCCCCTTTTCACAGAGAAATAAAGGTC
TAGAAGTAGTTGGTCCTCTGGCCTTAGTCATCAGCTTGGAGGAGGGGGCACCACCCCAGAGCCACAACATCTGCGCTTTTCTCTGGAGAA
GATCTTGTTACAGGACCCATTATACCCCTATGTCCCGAAAGAATACTCTGGGGATCCCCCCAGGAGTGCTGCTGGCCTTTGGGGTAGAGG
GTCCATGAGGTGCTCTGGGTGGTGTCCTGTAGTGCAGTTCAGATTCATAGATGTCGGCCGAGTATTTGGGGGGTTAAGAGCAGGTGCCTT
GGAACCAGACTGCCTGGGTCCAAATTGTGGCTCCTTCAGTTAATAGACGTGTGACTAGGAGTAGCTTGTTAAGTCTTTATGAGCTCAGTT
TTGTATTGTGTAAAATGAGAGTTACAGTAATACCTAGATTGCAGGGTGGGTGGCGAGGACCAAGTGAATTAGTACCTGGAAAGTGTGTAA
CAGTTTCAACATGAGAAGTACACAACATGAGAAGCAGAGTTAGCTGTACATTGCCAGAGAACCCCCTGTGGGCCATTTCCTGTGTTCTTG
AAGAAGACTTGGGCTTGGACCCTGTCCCCAGGAGGTCTCAGAGTAATCAGGACGGTACTAGGGAGAGAACTGTGGCAAGATAGATCAGTT
ATCTCGGTATCTATTCTCCCCTTCCTAATGTAGAAGCTCTGATTTTTAACTGGGCAGATGACTACATGGATTCAAGGTATTTTCCTAGTG
TCTCTTGAAATTAGGTGTGGTATTGTGACCAAATTCTAGCCAAAAAGATGTTGAACAGAAGTGGTATATGCAGCTTCTAGGAAGTGTTCT
TAAGGGGGAAGGCGTCATCCCCCACCTTTCCTCCTTCCTGCACTCTGGAATGTGGACCAGATGGCTGGAGTAGGAGCTGCCACCTGGGGC
CAGAAAATGATCTTAGGCGTGAAGGTCAAGTAAGGCAGGACAAGAGAGAAGGAGCCTGCCTCCCCGAGGCTGTGAAGAGCCATGCCAGTA

>41258_41258_5_KATNA1-PPP2R1A_KATNA1_chr6_149924403_ENST00000335647_PPP2R1A_chr19_52719781_ENST00000322088_length(amino acids)=503AA_BP=245
MNMSLLMISENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSVKDTYLQQKWQQVWQEINVEAKHVKDIMKTLESFKLDSTPLKAAQH
DLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHNDRGKAVRCREKKEQNKGREEKNKSPAAVTEPE
TNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPWKELVSDANQHVKSALASVIMGLSPIL
GKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSL
CMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANV

--------------------------------------------------------------
>41258_41258_6_KATNA1-PPP2R1A_KATNA1_chr6_149924403_ENST00000335647_PPP2R1A_chr19_52719781_ENST00000444322_length(transcript)=1806nt_BP=774nt
TAAAGTGTTTCTTTTTTTCTTCTTCTTTTTAGCTTACAGTTGAACATGAGTCTTCTTATGATTAGTGAGAATGTAAAATTGGCTCGTGAA
TATGCATTGCTGGGAAACTATGACTCTGCGATGGTCTATTATCAGGGAGTTCTTGACCAAATGAACAAGTATCTGTACTCAGTCAAAGAT
ACATACCTCCAGCAGAAATGGCAACAGGTTTGGCAGGAAATAAATGTGGAAGCTAAACATGTTAAAGATATCATGAAAACACTAGAGAGC
TTTAAACTGGACAGCACTCCCTTGAAAGCGGCACAGCATGACCTTCCAGCTTCTGAGGGAGAAGTCTGGTCCATGCCTGTACCTGTTGAA
CGAAGACCCTCACCAGGACCTAGAAAACGCCAATCTTCTCAGTACAGTGACCCTAAATCACATGGTAATCGTCCAAGTACAACTGTCAGA
GTTCACCGTTCATCTGCACAGAATGTTCACAATGACAGAGGGAAAGCTGTTCGTTGTCGTGAAAAGAAAGAACAGAATAAAGGAAGAGAG
GAAAAGAACAAATCACCTGCTGCAGTAACAGAACCAGAGACAAATAAATTTGATAGTACCGGATATGATAAAGACTTAGTAGAAGCTTTG
GAAAGAGATATAATTTCCCAGAATCCCAATGTTCGATGGGATGATATCGCTGATTTAGTAGAAGCTAAAAAGTTGCTTAAGGAAGCCGTA
GTGTTACCAATGTGGATGCCCGAATTCTTTAAGGGCATTAGGAGACCATGGAAAGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCT
GCCCTGGCCTCAGTCATCATGGGTCTCTCTCCCATCTTGGGCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTG
AAGGATGAGTGCCCTGAGGTACGGCTGAACATCATCTCTAACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCC
CTGCTCCCTGCCATTGTGGAGCTGGCTGAGGACGCCAAGTGGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAG
CTGGGAGTGGAGTTCTTTGATGAGAAACTTAACTCCTTGTGCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACC
AGCAACCTGAAGAAGCTAGTGGAAAAGTTTGGGAAGGAGTGGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCC
AACTACCTGCACCGCATGACTACGCTCTTCTGCATCAATGTGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCC
ACGGTTCTGCGCATGGCTGGGGACCCGGTTGCCAATGTCCGCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAAC
AGCACCTTGCAGAGTGAAGTCAAGCCCATCCTAGAGAAGCTGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTG
ACTGTTCTGTCTCTCGCCTGATGCTGGAAGAGGAGCAAACACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGA
GACACTGGGGGGCCTTTGGCTGTCACTCCCTGTGCATGGTCTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGG
GAAGATGTCTCACTGTCCACCTCCCAACGGGCTAGGGGAGCACGGGGTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCC

>41258_41258_6_KATNA1-PPP2R1A_KATNA1_chr6_149924403_ENST00000335647_PPP2R1A_chr19_52719781_ENST00000444322_length(amino acids)=503AA_BP=245
MNMSLLMISENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSVKDTYLQQKWQQVWQEINVEAKHVKDIMKTLESFKLDSTPLKAAQH
DLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHNDRGKAVRCREKKEQNKGREEKNKSPAAVTEPE
TNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPWKELVSDANQHVKSALASVIMGLSPIL
GKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSL
CMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANV

--------------------------------------------------------------
>41258_41258_7_KATNA1-PPP2R1A_KATNA1_chr6_149924404_ENST00000335647_PPP2R1A_chr19_52719782_ENST00000322088_length(transcript)=3004nt_BP=774nt
TAAAGTGTTTCTTTTTTTCTTCTTCTTTTTAGCTTACAGTTGAACATGAGTCTTCTTATGATTAGTGAGAATGTAAAATTGGCTCGTGAA
TATGCATTGCTGGGAAACTATGACTCTGCGATGGTCTATTATCAGGGAGTTCTTGACCAAATGAACAAGTATCTGTACTCAGTCAAAGAT
ACATACCTCCAGCAGAAATGGCAACAGGTTTGGCAGGAAATAAATGTGGAAGCTAAACATGTTAAAGATATCATGAAAACACTAGAGAGC
TTTAAACTGGACAGCACTCCCTTGAAAGCGGCACAGCATGACCTTCCAGCTTCTGAGGGAGAAGTCTGGTCCATGCCTGTACCTGTTGAA
CGAAGACCCTCACCAGGACCTAGAAAACGCCAATCTTCTCAGTACAGTGACCCTAAATCACATGGTAATCGTCCAAGTACAACTGTCAGA
GTTCACCGTTCATCTGCACAGAATGTTCACAATGACAGAGGGAAAGCTGTTCGTTGTCGTGAAAAGAAAGAACAGAATAAAGGAAGAGAG
GAAAAGAACAAATCACCTGCTGCAGTAACAGAACCAGAGACAAATAAATTTGATAGTACCGGATATGATAAAGACTTAGTAGAAGCTTTG
GAAAGAGATATAATTTCCCAGAATCCCAATGTTCGATGGGATGATATCGCTGATTTAGTAGAAGCTAAAAAGTTGCTTAAGGAAGCCGTA
GTGTTACCAATGTGGATGCCCGAATTCTTTAAGGGCATTAGGAGACCATGGAAAGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCT
GCCCTGGCCTCAGTCATCATGGGTCTCTCTCCCATCTTGGGCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTG
AAGGATGAGTGCCCTGAGGTACGGCTGAACATCATCTCTAACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCC
CTGCTCCCTGCCATTGTGGAGCTGGCTGAGGACGCCAAGTGGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAG
CTGGGAGTGGAGTTCTTTGATGAGAAACTTAACTCCTTGTGCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACC
AGCAACCTGAAGAAGCTAGTGGAAAAGTTTGGGAAGGAGTGGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCC
AACTACCTGCACCGCATGACTACGCTCTTCTGCATCAATGTGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCC
ACGGTTCTGCGCATGGCTGGGGACCCGGTTGCCAATGTCCGCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAAC
AGCACCTTGCAGAGTGAAGTCAAGCCCATCCTAGAGAAGCTGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTG
ACTGTTCTGTCTCTCGCCTGATGCTGGAAGAGGAGCAAACACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGA
GACACTGGGGGGCCTTTGGCTGTCACTCCCTGTGCATGGTCTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGG
GAAGATGTCTCACTGTCCACCTCCCAACGGGCTAGGGGAGCACGGGGTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCC
ACGTCAGGGAGAGATGTGAGCATCCCGGGTCACTGGATCCTGCTGCTGTAATGGGAACCCCTCCCCCATTTACTTCTCCACCTCCCGTCC
TCCCCATCATTGGTTTTTTTTTGTGTGTCAACTGTGCCGTTTTTATTTTATTCCTTTTATTTTCCCCCTTTTCACAGAGAAATAAAGGTC
TAGAAGTAGTTGGTCCTCTGGCCTTAGTCATCAGCTTGGAGGAGGGGGCACCACCCCAGAGCCACAACATCTGCGCTTTTCTCTGGAGAA
GATCTTGTTACAGGACCCATTATACCCCTATGTCCCGAAAGAATACTCTGGGGATCCCCCCAGGAGTGCTGCTGGCCTTTGGGGTAGAGG
GTCCATGAGGTGCTCTGGGTGGTGTCCTGTAGTGCAGTTCAGATTCATAGATGTCGGCCGAGTATTTGGGGGGTTAAGAGCAGGTGCCTT
GGAACCAGACTGCCTGGGTCCAAATTGTGGCTCCTTCAGTTAATAGACGTGTGACTAGGAGTAGCTTGTTAAGTCTTTATGAGCTCAGTT
TTGTATTGTGTAAAATGAGAGTTACAGTAATACCTAGATTGCAGGGTGGGTGGCGAGGACCAAGTGAATTAGTACCTGGAAAGTGTGTAA
CAGTTTCAACATGAGAAGTACACAACATGAGAAGCAGAGTTAGCTGTACATTGCCAGAGAACCCCCTGTGGGCCATTTCCTGTGTTCTTG
AAGAAGACTTGGGCTTGGACCCTGTCCCCAGGAGGTCTCAGAGTAATCAGGACGGTACTAGGGAGAGAACTGTGGCAAGATAGATCAGTT
ATCTCGGTATCTATTCTCCCCTTCCTAATGTAGAAGCTCTGATTTTTAACTGGGCAGATGACTACATGGATTCAAGGTATTTTCCTAGTG
TCTCTTGAAATTAGGTGTGGTATTGTGACCAAATTCTAGCCAAAAAGATGTTGAACAGAAGTGGTATATGCAGCTTCTAGGAAGTGTTCT
TAAGGGGGAAGGCGTCATCCCCCACCTTTCCTCCTTCCTGCACTCTGGAATGTGGACCAGATGGCTGGAGTAGGAGCTGCCACCTGGGGC
CAGAAAATGATCTTAGGCGTGAAGGTCAAGTAAGGCAGGACAAGAGAGAAGGAGCCTGCCTCCCCGAGGCTGTGAAGAGCCATGCCAGTA

>41258_41258_7_KATNA1-PPP2R1A_KATNA1_chr6_149924404_ENST00000335647_PPP2R1A_chr19_52719782_ENST00000322088_length(amino acids)=503AA_BP=245
MNMSLLMISENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSVKDTYLQQKWQQVWQEINVEAKHVKDIMKTLESFKLDSTPLKAAQH
DLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHNDRGKAVRCREKKEQNKGREEKNKSPAAVTEPE
TNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPWKELVSDANQHVKSALASVIMGLSPIL
GKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSL
CMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANV

--------------------------------------------------------------
>41258_41258_8_KATNA1-PPP2R1A_KATNA1_chr6_149924404_ENST00000335647_PPP2R1A_chr19_52719782_ENST00000444322_length(transcript)=1806nt_BP=774nt
TAAAGTGTTTCTTTTTTTCTTCTTCTTTTTAGCTTACAGTTGAACATGAGTCTTCTTATGATTAGTGAGAATGTAAAATTGGCTCGTGAA
TATGCATTGCTGGGAAACTATGACTCTGCGATGGTCTATTATCAGGGAGTTCTTGACCAAATGAACAAGTATCTGTACTCAGTCAAAGAT
ACATACCTCCAGCAGAAATGGCAACAGGTTTGGCAGGAAATAAATGTGGAAGCTAAACATGTTAAAGATATCATGAAAACACTAGAGAGC
TTTAAACTGGACAGCACTCCCTTGAAAGCGGCACAGCATGACCTTCCAGCTTCTGAGGGAGAAGTCTGGTCCATGCCTGTACCTGTTGAA
CGAAGACCCTCACCAGGACCTAGAAAACGCCAATCTTCTCAGTACAGTGACCCTAAATCACATGGTAATCGTCCAAGTACAACTGTCAGA
GTTCACCGTTCATCTGCACAGAATGTTCACAATGACAGAGGGAAAGCTGTTCGTTGTCGTGAAAAGAAAGAACAGAATAAAGGAAGAGAG
GAAAAGAACAAATCACCTGCTGCAGTAACAGAACCAGAGACAAATAAATTTGATAGTACCGGATATGATAAAGACTTAGTAGAAGCTTTG
GAAAGAGATATAATTTCCCAGAATCCCAATGTTCGATGGGATGATATCGCTGATTTAGTAGAAGCTAAAAAGTTGCTTAAGGAAGCCGTA
GTGTTACCAATGTGGATGCCCGAATTCTTTAAGGGCATTAGGAGACCATGGAAAGAGCTGGTGTCCGATGCCAACCAACATGTCAAGTCT
GCCCTGGCCTCAGTCATCATGGGTCTCTCTCCCATCTTGGGCAAAGACAACACCATCGAGCACCTCTTGCCCCTCTTCCTGGCTCAGCTG
AAGGATGAGTGCCCTGAGGTACGGCTGAACATCATCTCTAACCTGGACTGTGTGAACGAGGTGATTGGCATCCGGCAGCTGTCCCAGTCC
CTGCTCCCTGCCATTGTGGAGCTGGCTGAGGACGCCAAGTGGCGGGTGCGGCTGGCCATCATTGAGTACATGCCCCTCCTGGCTGGACAG
CTGGGAGTGGAGTTCTTTGATGAGAAACTTAACTCCTTGTGCATGGCCTGGCTTGTGGATCATGTATATGCCATCCGCGAGGCAGCCACC
AGCAACCTGAAGAAGCTAGTGGAAAAGTTTGGGAAGGAGTGGGCCCATGCCACAATCATCCCCAAGGTCTTGGCCATGTCCGGAGACCCC
AACTACCTGCACCGCATGACTACGCTCTTCTGCATCAATGTGCTGTCTGAGGTCTGTGGGCAGGACATCACCACCAAGCACATGCTACCC
ACGGTTCTGCGCATGGCTGGGGACCCGGTTGCCAATGTCCGCTTCAATGTGGCCAAGTCTCTGCAGAAGATAGGGCCCATCCTGGACAAC
AGCACCTTGCAGAGTGAAGTCAAGCCCATCCTAGAGAAGCTGACCCAGGACCAGGATGTGGACGTCAAATACTTTGCCCAGGAGGCTCTG
ACTGTTCTGTCTCTCGCCTGATGCTGGAAGAGGAGCAAACACTGGCCTCTGGTGTCCACCCTCCAACCCCCACAAGTCCCTCTTTGGGGA
GACACTGGGGGGCCTTTGGCTGTCACTCCCTGTGCATGGTCTGACCCCAGGCCCCTTCCCCCAGCACGGTTCCTCCTCTCCCCAGCCTGG
GAAGATGTCTCACTGTCCACCTCCCAACGGGCTAGGGGAGCACGGGGTTGGACAGGACAGTGACCTTGGGAGGAAGGGGCTACTCCGCCC

>41258_41258_8_KATNA1-PPP2R1A_KATNA1_chr6_149924404_ENST00000335647_PPP2R1A_chr19_52719782_ENST00000444322_length(amino acids)=503AA_BP=245
MNMSLLMISENVKLAREYALLGNYDSAMVYYQGVLDQMNKYLYSVKDTYLQQKWQQVWQEINVEAKHVKDIMKTLESFKLDSTPLKAAQH
DLPASEGEVWSMPVPVERRPSPGPRKRQSSQYSDPKSHGNRPSTTVRVHRSSAQNVHNDRGKAVRCREKKEQNKGREEKNKSPAAVTEPE
TNKFDSTGYDKDLVEALERDIISQNPNVRWDDIADLVEAKKLLKEAVVLPMWMPEFFKGIRRPWKELVSDANQHVKSALASVIMGLSPIL
GKDNTIEHLLPLFLAQLKDECPEVRLNIISNLDCVNEVIGIRQLSQSLLPAIVELAEDAKWRVRLAIIEYMPLLAGQLGVEFFDEKLNSL
CMAWLVDHVYAIREAATSNLKKLVEKFGKEWAHATIIPKVLAMSGDPNYLHRMTTLFCINVLSEVCGQDITTKHMLPTVLRMAGDPVANV

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for KATNA1-PPP2R1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneKATNA1chr6:149922729chr19:52719781ENST00000335643-581_75220.0312.0dynein and NDEL1
HgeneKATNA1chr6:149922729chr19:52719781ENST00000335647-6101_75296.0492.0dynein and NDEL1
HgeneKATNA1chr6:149922729chr19:52719781ENST00000367411-7111_75296.0492.0dynein and NDEL1
HgeneKATNA1chr6:149922730chr19:52719782ENST00000335643-581_75220.0312.0dynein and NDEL1
HgeneKATNA1chr6:149922730chr19:52719782ENST00000335647-6101_75296.0492.0dynein and NDEL1
HgeneKATNA1chr6:149922730chr19:52719782ENST00000367411-7111_75296.0492.0dynein and NDEL1
HgeneKATNA1chr6:149924403chr19:52719781ENST00000335647-5101_75243.0492.0dynein and NDEL1
HgeneKATNA1chr6:149924403chr19:52719781ENST00000367411-6111_75243.0492.0dynein and NDEL1
HgeneKATNA1chr6:149924404chr19:52719782ENST00000335647-5101_75243.0492.0dynein and NDEL1
HgeneKATNA1chr6:149924404chr19:52719782ENST00000367411-6111_75243.0492.0dynein and NDEL1
HgeneKATNA1chr6:149922729chr19:52719781ENST00000335643-581_29220.0312.0KATNB1
HgeneKATNA1chr6:149922729chr19:52719781ENST00000335647-6101_29296.0492.0KATNB1
HgeneKATNA1chr6:149922729chr19:52719781ENST00000367411-7111_29296.0492.0KATNB1
HgeneKATNA1chr6:149922730chr19:52719782ENST00000335643-581_29220.0312.0KATNB1
HgeneKATNA1chr6:149922730chr19:52719782ENST00000335647-6101_29296.0492.0KATNB1
HgeneKATNA1chr6:149922730chr19:52719782ENST00000367411-7111_29296.0492.0KATNB1
HgeneKATNA1chr6:149924403chr19:52719781ENST00000335647-5101_29243.0492.0KATNB1
HgeneKATNA1chr6:149924403chr19:52719781ENST00000367411-6111_29243.0492.0KATNB1
HgeneKATNA1chr6:149924404chr19:52719782ENST00000335647-5101_29243.0492.0KATNB1
HgeneKATNA1chr6:149924404chr19:52719782ENST00000367411-6111_29243.0492.0KATNB1
HgeneKATNA1chr6:149922729chr19:52719781ENST00000335643-581_185220.0312.0microtubules
HgeneKATNA1chr6:149922729chr19:52719781ENST00000335647-6101_185296.0492.0microtubules
HgeneKATNA1chr6:149922729chr19:52719781ENST00000367411-7111_185296.0492.0microtubules
HgeneKATNA1chr6:149922730chr19:52719782ENST00000335643-581_185220.0312.0microtubules
HgeneKATNA1chr6:149922730chr19:52719782ENST00000335647-6101_185296.0492.0microtubules
HgeneKATNA1chr6:149922730chr19:52719782ENST00000367411-7111_185296.0492.0microtubules
HgeneKATNA1chr6:149924403chr19:52719781ENST00000335647-5101_185243.0492.0microtubules
HgeneKATNA1chr6:149924403chr19:52719781ENST00000367411-6111_185243.0492.0microtubules
HgeneKATNA1chr6:149924404chr19:52719782ENST00000335647-5101_185243.0492.0microtubules
HgeneKATNA1chr6:149924404chr19:52719782ENST00000367411-6111_185243.0492.0microtubules


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneKATNA1chr6:149924403chr19:52719781ENST00000335643-181_750312.0dynein and NDEL1
HgeneKATNA1chr6:149924404chr19:52719782ENST00000335643-181_750312.0dynein and NDEL1
HgeneKATNA1chr6:149924403chr19:52719781ENST00000335643-181_290312.0KATNB1
HgeneKATNA1chr6:149924404chr19:52719782ENST00000335643-181_290312.0KATNB1
HgeneKATNA1chr6:149924403chr19:52719781ENST00000335643-181_1850312.0microtubules
HgeneKATNA1chr6:149924404chr19:52719782ENST00000335643-181_1850312.0microtubules


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for KATNA1-PPP2R1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for KATNA1-PPP2R1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource