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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KAZN-PRDM2 (FusionGDB2 ID:41288)

Fusion Gene Summary for KAZN-PRDM2

check button Fusion gene summary
Fusion gene informationFusion gene name: KAZN-PRDM2
Fusion gene ID: 41288
HgeneTgene
Gene symbol

KAZN

PRDM2

Gene ID

23254

7799

Gene namekazrin, periplakin interacting proteinPR/SET domain 2
SynonymsC1orf196|KAZHUMHOXY1|KMT8|KMT8A|MTB-ZF|RIZ|RIZ1|RIZ2
Cytomap

1p36.21

1p36.21

Type of geneprotein-codingprotein-coding
DescriptionkazrinPR domain zinc finger protein 2GATA-3 binding protein G3BMTE-binding proteinPR domain 2PR domain containing 2, with ZNF domainPR domain-containing protein 2lysine N-methyltransferase 8retinoblastoma protein-binding zinc finger proteinretinoblastom
Modification date2020031320200313
UniProtAcc

Q674X7

.
Ensembl transtripts involved in fusion geneENST00000361144, ENST00000376030, 
ENST00000400797, ENST00000400798, 
ENST00000422387, ENST00000503743, 
ENST00000235372, ENST00000311066, 
ENST00000343137, ENST00000413440, 
ENST00000502727, ENST00000503842, 
ENST00000505823, ENST00000376048, 
Fusion gene scores* DoF score15 X 11 X 8=132010 X 8 X 4=320
# samples 1811
** MAII scorelog2(18/1320*10)=-2.87446911791614
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/320*10)=-1.5405683813627
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KAZN [Title/Abstract] AND PRDM2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKAZN(15287371)-PRDM2(14142921), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgenePRDM2

GO:0045944

positive regulation of transcription by RNA polymerase II

8654390


check buttonFusion gene breakpoints across KAZN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PRDM2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4THCATCGA-EM-A4FUKAZNchr1

15287371

+PRDM2chr1

14142921

+


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Fusion Gene ORF analysis for KAZN-PRDM2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000361144ENST00000235372KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000361144ENST00000311066KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000361144ENST00000343137KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000361144ENST00000413440KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000361144ENST00000502727KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000361144ENST00000503842KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000361144ENST00000505823KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000376030ENST00000235372KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000376030ENST00000311066KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000376030ENST00000343137KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000376030ENST00000413440KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000376030ENST00000502727KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000376030ENST00000503842KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000376030ENST00000505823KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400797ENST00000235372KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400797ENST00000311066KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400797ENST00000343137KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400797ENST00000413440KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400797ENST00000502727KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400797ENST00000503842KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400797ENST00000505823KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400798ENST00000235372KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400798ENST00000311066KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400798ENST00000343137KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400798ENST00000413440KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400798ENST00000502727KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400798ENST00000503842KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000400798ENST00000505823KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000422387ENST00000235372KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000422387ENST00000311066KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000422387ENST00000343137KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000422387ENST00000413440KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000422387ENST00000502727KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000422387ENST00000503842KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000422387ENST00000505823KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000503743ENST00000235372KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000503743ENST00000311066KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000503743ENST00000343137KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000503743ENST00000413440KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000503743ENST00000502727KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000503743ENST00000503842KAZNchr1

15287371

+PRDM2chr1

14142921

+
5CDS-intronENST00000503743ENST00000505823KAZNchr1

15287371

+PRDM2chr1

14142921

+
In-frameENST00000361144ENST00000376048KAZNchr1

15287371

+PRDM2chr1

14142921

+
In-frameENST00000376030ENST00000376048KAZNchr1

15287371

+PRDM2chr1

14142921

+
In-frameENST00000400797ENST00000376048KAZNchr1

15287371

+PRDM2chr1

14142921

+
In-frameENST00000400798ENST00000376048KAZNchr1

15287371

+PRDM2chr1

14142921

+
In-frameENST00000422387ENST00000376048KAZNchr1

15287371

+PRDM2chr1

14142921

+
In-frameENST00000503743ENST00000376048KAZNchr1

15287371

+PRDM2chr1

14142921

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000376030KAZNchr115287371+ENST00000376048PRDM2chr114142921+2763712150881243
ENST00000503743KAZNchr115287371+ENST00000376048PRDM2chr114142921+2678627137796219
ENST00000422387KAZNchr115287371+ENST00000376048PRDM2chr114142921+2750699137868243
ENST00000361144KAZNchr115287371+ENST00000376048PRDM2chr114142921+26866356031201
ENST00000400798KAZNchr115287371+ENST00000376048PRDM2chr114142921+248843719606195
ENST00000400797KAZNchr115287371+ENST00000376048PRDM2chr114142921+249844716541286122

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000376030ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.0158592870.98414075
ENST00000503743ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.0126870950.98731285
ENST00000422387ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.0135553250.98644465
ENST00000361144ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.156923590.84307635
ENST00000400798ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.58984390.41015613
ENST00000400797ENST00000376048KAZNchr115287371+PRDM2chr114142921+0.175020650.82497936

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Fusion Genomic Features for KAZN-PRDM2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KAZNchr115287371+PRDM2chr114142921+5.20E-050.999948
KAZNchr115287371+PRDM2chr114142921+5.20E-050.999948

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for KAZN-PRDM2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:15287371/chr1:14142921)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KAZN

Q674X7

.
FUNCTION: Component of the cornified envelope of keratinocytes. May be involved in the interplay between adherens junctions and desmosomes. The function in the nucleus is not known. {ECO:0000269|PubMed:15337775}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091052_107401683.0Compositional biasNote=Poly-Ser
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091361_144701683.0Compositional biasNote=Arg/Lys-rich (basic)
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609268_29601683.0Compositional biasNote=Asp/Glu-rich (acidic)
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609933_104901683.0Compositional biasNote=Pro-rich
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581052_1074170227.0Compositional biasNote=Poly-Ser
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581361_1447170227.0Compositional biasNote=Arg/Lys-rich (basic)
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858268_296170227.0Compositional biasNote=Asp/Glu-rich (acidic)
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858933_1049170227.0Compositional biasNote=Pro-rich
TgenePRDM2chr1:15287371chr1:14142921ENST000003110660928_14101683.0DomainSET
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091028_105201683.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609970_97901683.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609985_99801683.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581028_1052170227.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858970_979170227.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858985_998170227.0MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609294_31601683.0RegionNote=Retinoblastoma protein binding
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858294_316170227.0RegionNote=Retinoblastoma protein binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091134_115601683.0Zinc fingerC2H2-type 4
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091162_118501683.0Zinc fingerC2H2-type 5
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091191_121401683.0Zinc fingerC2H2-type 6
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091333_135501683.0Zinc fingerC2H2-type 7%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST00000311066091455_147801683.0Zinc fingerC2H2-type 8%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609360_38201683.0Zinc fingerC2H2-type 1
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609390_41201683.0Zinc fingerC2H2-type 2
TgenePRDM2chr1:15287371chr1:14142921ENST0000031106609483_50601683.0Zinc fingerC2H2-type 3
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581134_1156170227.0Zinc fingerC2H2-type 4
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581162_1185170227.0Zinc fingerC2H2-type 5
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581191_1214170227.0Zinc fingerC2H2-type 6
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581333_1355170227.0Zinc fingerC2H2-type 7%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST00000376048581455_1478170227.0Zinc fingerC2H2-type 8%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858360_382170227.0Zinc fingerC2H2-type 1
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858390_412170227.0Zinc fingerC2H2-type 2
TgenePRDM2chr1:15287371chr1:14142921ENST0000037604858483_506170227.0Zinc fingerC2H2-type 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+2874_256133416.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+21574_256139776.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+2874_25645328.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+2874_25645328.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+2874_256139422.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+3974_256139422.0Coiled coilOntology_term=ECO:0000255
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28375_382133416.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215375_382139776.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28375_38245328.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28375_38245328.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28375_382139422.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39375_382139422.0Compositional biasNote=Poly-Lys
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28446_511133416.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28524_588133416.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28612_679133416.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215446_511139776.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215524_588139776.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215612_679139776.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28446_51145328.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28524_58845328.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28612_67945328.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28446_51145328.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28524_58845328.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28612_67945328.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28446_511139422.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28524_588139422.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28612_679139422.0DomainSAM 3
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39446_511139422.0DomainSAM 1
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39524_588139422.0DomainSAM 2
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39612_679139422.0DomainSAM 3
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101052_107416782095.6666666666665Compositional biasNote=Poly-Ser
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101361_144716782095.6666666666665Compositional biasNote=Arg/Lys-rich (basic)
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710268_29616782095.6666666666665Compositional biasNote=Asp/Glu-rich (acidic)
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710933_104916782095.6666666666665Compositional biasNote=Pro-rich
TgenePRDM2chr1:15287371chr1:14142921ENST0000023537271028_14116782095.6666666666665DomainSET
TgenePRDM2chr1:15287371chr1:14142921ENST000003760485828_141170227.0DomainSET
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101028_105216782095.6666666666665MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710970_97916782095.6666666666665MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710985_99816782095.6666666666665MotifSH3-binding
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710294_31616782095.6666666666665RegionNote=Retinoblastoma protein binding
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101134_115616782095.6666666666665Zinc fingerC2H2-type 4
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101162_118516782095.6666666666665Zinc fingerC2H2-type 5
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101191_121416782095.6666666666665Zinc fingerC2H2-type 6
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101333_135516782095.6666666666665Zinc fingerC2H2-type 7%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST000002353727101455_147816782095.6666666666665Zinc fingerC2H2-type 8%3B atypical
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710360_38216782095.6666666666665Zinc fingerC2H2-type 1
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710390_41216782095.6666666666665Zinc fingerC2H2-type 2
TgenePRDM2chr1:15287371chr1:14142921ENST00000235372710483_50616782095.6666666666665Zinc fingerC2H2-type 3


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Fusion Gene Sequence for KAZN-PRDM2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>41288_41288_1_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000361144_PRDM2_chr1_14142921_ENST00000376048_length(transcript)=2686nt_BP=635nt
AGCCGTTCCCACGTGAGAGGCTCCGCGGCCGAATTCCTCGCGTGCAGCAGGCGCGGACCGCCCGGCGTCCGGCCGGACTGAGAGCCCTGG
TCCGGCGCGCGCCGCCGGCCGGGCGGGAGGCGGGGGCGGGCTCGGCTGCGCCCCGATGCGGCGGCGACCTCCGGGTCTGTGAGCCCGGCG
CGCGCCGTCGGAGCCCCTCGCGCAGCCGCTGGTAGCGTCCCCCCGGGCACCCGGCATGCGGGCGGCCGACTCGGGCTCGTGGGAGCGCGT
CCGCCAGCTCGCGGCGCAGGGCGAGCCGGCGCCTTCCTGCGGGGCGGGGGCCGGGCCCGCGCGGCCCCCGGGACCCGCAGCCTGCGAGCA
GTGCGTGGACGCGGCGGGGCCCGGCGATCGGCCCCGCGCCGGGGTTCCCCGGGTCCGAGCGGATGGCGACTGCAGCCAGCCCGTGCTCCT
GCGGGAAGAAGTGTCGCGGCTCCAGGAGGAAGTTCACCTTCTCCGGCAGATGAAGGAGATGTTGGCGAAGGACCTGGAGGAGTCGCAGGG
CGGCAAGTCCTCTGAGGTCCTCTCGGCCACCGAGCTCAGGGTCCAGCTGGCCCAGAAGGAGCAGGAGCTAGCCAGAGCCAAAGAAGCCTT
GCAGGCTACAGCCTCCGCTTGGCGTCCCGATGCTCTCCACCAGCGGCCCCGTACATCACCAGGCAGTATAGGAAGGTCAAAGCTCCAGCT
GCAGCCCAGTTCCAGGGACCATTCTTCAAAGAGTAGACACTCTGGCTGCTCCCTGACAGCACCTGAAGTGACCTGGAATCAGTGAAGCCA
AAGGGACTGGCAGTCTGCCCTGCAGGGAGTACCGACCTATCCCAGTTGTGTGAGGCTGCGAGAGAAAGGGAGTGCATGTGCGCGCGTGCA
TGTGTGCGTGCGTGTGTGTTCACGTGTTCTCGTGCGGGCGCGTGAGTGGTCTTCAAACGAGGGTCCCGATCCCCGGGGCGGCAGGAAGGG
GGCCGACTCCACGCTGTCCTTTGGGATGATACTTGGATGCAGCTCTTGGGACCGTGTTCTGCAGCCCAGCCTTCCTGTTGGGGTGGGGCC
TCTCCTACTATGCAATTTTTCAAGAGCTCCTTGACCCTGCTTTTTGCTTCTTGAGTTGTCTTTTGCCATTATGGGGACTTTGGTTTGACC
CAGGGGTCAGCCTTAGGAAGGCCTTCAGGAGGAGGCCGAGTTCCCCTTCAGTACCACCCCTCTCTCCCCACCTTCCCTCTCCCGGCAACA
TCTCTGGGAATCAACAGCATATTGACACGTTGGAGCCGAGCCTGAACATGCCCCTCGGCCCCAGCACATGGAAAACCCCCTTCCTTGCCT
AAGGTGTCTGAGTTTCTGGCTCTTGAGGCATTTCCAGACTTGAAATTCTCATCAGTCCATTGCTCTTGAGTCTTTGCAGAGAACCTCAGA
TCAGGTGCACCTGGGAGAAAGACTTTGTCCCCACTTACAGATCTATCTCCTCCCTTGGGAAGGGCAGGGAATGGGGACGGTGTATGGAGG
GGAGGGATCTCCTGCGCCCTTCATTGCCACACTTGGTGGGACCATGAACATCTTTAGTGTCTGAGCTTCTCAAATTAGCTGCAATAGGAA
AAAAACAAATTGGGAAATGAAAAAAAAATGGGAAGATTAAAAAGCACAGGGGGAAGAAGAAGAGATTTCGGAGGCCATCCTGCCAGGGGC
GGACGGGGCTGACTCCTGCTCTCTGGAGGACGGTCAGTCCATGTCTCGGAGAAACGGGTGAGCTGAGCTTGGCGTTTGGACCCAGTTCAG
TGAGGTTCTTGGGTTTTGTGCCTTTGGGGCAGACCCCAGGCAAGGATGTCTGAGACCACTTGGGCGCTGTTTTCTCAGCTCCAATTTCAA
GAGTGAGCTATCAAACCCAGAGCGGAAGGAGGGAGCTCTGATGAGCACGGTTTGTCACACGATAAAGGGATTTTTTTTTTCAGGGCTACT
ACGGTTGATCTTGCAACTCTGTAAATATGTATGTAGACACTTTTAAAAGCACGTATTTATGTCCCTGACTGTAAATGCTCCATTTTTAAA
GTTTTATAACTTGTGTTATTTAATGAGTCAGTCAATCGGCTGCAGTATGGGATCTGATAAGGATCTAGGAGAAGGGTCTCATGCGGACCC
TCACATGGGCAGAAAAATGGTGGTCATTGGCCGACATCACAGTTTTCCTGTTTCCCACCCAGCTAAAAACCGTTGTTTGCTTTAAATTTT
CATAAACTGGAATCCTTTCACCCGCTCCTACAGCTAACCCTCACAAGCATGAAGTGCTGTGGCTGTTCCTTATCCTAATGATGCGCTTTT
GTCCCGTAAATGTTAACACTCATGAAGCATACCCCGGCCTCTCAGTTCTTGAGGGCCTCCCCACCGCAGCAGCAAGGAAAGCTCACGAAC
CCCAAACCTGGCAAGTCACCTGCAGCCCATGGTGAGCTCTGGGAAGTGTGGTTGAGGCCTTGGGGTCACTCCTTTTTTGCATGTGCAAAT
GTGCTGGTCACCCTTCAACGCTCCCAGACGGTCAGGAAAACTGTTCCAATCATGAAAAGGGGGGATGATTTTGTAAAAGTGGCATTTCCT

>41288_41288_1_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000361144_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=201AA_BP=
MLLLGQLDPELGGREDLRGLAALRLLQVLRQHLLHLPEKVNFLLEPRHFFPQEHGLAAVAIRSDPGNPGAGPIAGPRRVHALLAGCGSRG
PRGPGPRPAGRRRLALRRELADALPRARVGRPHAGCPGGRYQRLREGLRRRAPGSQTRRSPPHRGAAEPAPASRPAGGARRTRALSPAGR

--------------------------------------------------------------
>41288_41288_2_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000376030_PRDM2_chr1_14142921_ENST00000376048_length(transcript)=2763nt_BP=712nt
GCGCCCGCCCGCCGGGGTCTCGGCGATCGCTGCTCCTCCTCCTCCTTCTCCTCCTCTTTTTTCTCCTCCGCCTCCTCCCCCCGCCGCCTC
GCCACCGCCGCGGCTAGGGCTGGAGGCGCCGCTGTCATTCCTGTGCCGGAGGAACCGGCGCTGCCGGTGCCTGGGGGTCGGGGCGCGGGC
GAAGCCGGGCCGCGGAGGACACAACAGGTAGAGCCGGGGGTGCCCGGCCGCGCGCCCCCCGCGCATCATGCAGCTCTTTGTCACCTCTCT
CGCCCCCAGGCCAAAATCCTGAGCATGATGGAAGACAATAAGCAGCTCGCGCTCCGCATCGATGGGGCGGTCCAGTCGGCCAGCCAGGAG
GTGACCAACCTGCGAGCCGAACTCACGGCCACCAACCGGAGACTGGCGGAACTGAGCGGCGGCGGCGGCCCCGGCCCGGGCCCGGGAGCC
GCGGCCAGCGCCTCGGCGGCGGGGGACTCGGCGGCGACGAACATGGAGAACCCCCAGCTTGGAGCGCAAGTGCTCCTGCGGGAAGAAGTG
TCGCGGCTCCAGGAGGAAGTTCACCTTCTCCGGCAGATGAAGGAGATGTTGGCGAAGGACCTGGAGGAGTCGCAGGGCGGCAAGTCCTCT
GAGGTCCTCTCGGCCACCGAGCTCAGGGTCCAGCTGGCCCAGAAGGAGCAGGAGCTAGCCAGAGCCAAAGAAGCCTTGCAGGCTACAGCC
TCCGCTTGGCGTCCCGATGCTCTCCACCAGCGGCCCCGTACATCACCAGGCAGTATAGGAAGGTCAAAGCTCCAGCTGCAGCCCAGTTCC
AGGGACCATTCTTCAAAGAGTAGACACTCTGGCTGCTCCCTGACAGCACCTGAAGTGACCTGGAATCAGTGAAGCCAAAGGGACTGGCAG
TCTGCCCTGCAGGGAGTACCGACCTATCCCAGTTGTGTGAGGCTGCGAGAGAAAGGGAGTGCATGTGCGCGCGTGCATGTGTGCGTGCGT
GTGTGTTCACGTGTTCTCGTGCGGGCGCGTGAGTGGTCTTCAAACGAGGGTCCCGATCCCCGGGGCGGCAGGAAGGGGGCCGACTCCACG
CTGTCCTTTGGGATGATACTTGGATGCAGCTCTTGGGACCGTGTTCTGCAGCCCAGCCTTCCTGTTGGGGTGGGGCCTCTCCTACTATGC
AATTTTTCAAGAGCTCCTTGACCCTGCTTTTTGCTTCTTGAGTTGTCTTTTGCCATTATGGGGACTTTGGTTTGACCCAGGGGTCAGCCT
TAGGAAGGCCTTCAGGAGGAGGCCGAGTTCCCCTTCAGTACCACCCCTCTCTCCCCACCTTCCCTCTCCCGGCAACATCTCTGGGAATCA
ACAGCATATTGACACGTTGGAGCCGAGCCTGAACATGCCCCTCGGCCCCAGCACATGGAAAACCCCCTTCCTTGCCTAAGGTGTCTGAGT
TTCTGGCTCTTGAGGCATTTCCAGACTTGAAATTCTCATCAGTCCATTGCTCTTGAGTCTTTGCAGAGAACCTCAGATCAGGTGCACCTG
GGAGAAAGACTTTGTCCCCACTTACAGATCTATCTCCTCCCTTGGGAAGGGCAGGGAATGGGGACGGTGTATGGAGGGGAGGGATCTCCT
GCGCCCTTCATTGCCACACTTGGTGGGACCATGAACATCTTTAGTGTCTGAGCTTCTCAAATTAGCTGCAATAGGAAAAAAACAAATTGG
GAAATGAAAAAAAAATGGGAAGATTAAAAAGCACAGGGGGAAGAAGAAGAGATTTCGGAGGCCATCCTGCCAGGGGCGGACGGGGCTGAC
TCCTGCTCTCTGGAGGACGGTCAGTCCATGTCTCGGAGAAACGGGTGAGCTGAGCTTGGCGTTTGGACCCAGTTCAGTGAGGTTCTTGGG
TTTTGTGCCTTTGGGGCAGACCCCAGGCAAGGATGTCTGAGACCACTTGGGCGCTGTTTTCTCAGCTCCAATTTCAAGAGTGAGCTATCA
AACCCAGAGCGGAAGGAGGGAGCTCTGATGAGCACGGTTTGTCACACGATAAAGGGATTTTTTTTTTCAGGGCTACTACGGTTGATCTTG
CAACTCTGTAAATATGTATGTAGACACTTTTAAAAGCACGTATTTATGTCCCTGACTGTAAATGCTCCATTTTTAAAGTTTTATAACTTG
TGTTATTTAATGAGTCAGTCAATCGGCTGCAGTATGGGATCTGATAAGGATCTAGGAGAAGGGTCTCATGCGGACCCTCACATGGGCAGA
AAAATGGTGGTCATTGGCCGACATCACAGTTTTCCTGTTTCCCACCCAGCTAAAAACCGTTGTTTGCTTTAAATTTTCATAAACTGGAAT
CCTTTCACCCGCTCCTACAGCTAACCCTCACAAGCATGAAGTGCTGTGGCTGTTCCTTATCCTAATGATGCGCTTTTGTCCCGTAAATGT
TAACACTCATGAAGCATACCCCGGCCTCTCAGTTCTTGAGGGCCTCCCCACCGCAGCAGCAAGGAAAGCTCACGAACCCCAAACCTGGCA
AGTCACCTGCAGCCCATGGTGAGCTCTGGGAAGTGTGGTTGAGGCCTTGGGGTCACTCCTTTTTTGCATGTGCAAATGTGCTGGTCACCC
TTCAACGCTCCCAGACGGTCAGGAAAACTGTTCCAATCATGAAAAGGGGGGATGATTTTGTAAAAGTGGCATTTCCTGGTCAGTGGTGGT

>41288_41288_2_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000376030_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=243AA_BP=187
MPVPGGRGAGEAGPRRTQQVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSG
GGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELA

--------------------------------------------------------------
>41288_41288_3_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000400797_PRDM2_chr1_14142921_ENST00000376048_length(transcript)=2498nt_BP=447nt
GCATCAGCAGCTGTCTGCCAGTGTTGACGGAGGGCTCATGGGTGCCAGGCCGCTTGCTGGGGCTTTTTATCTGTCCTCAGGCATTGGCAC
AGCAGCCCTGGGAGATGAATACTATTGTGATCTTCATTCTCCACACAAGGACAGGGAAGTGACGTGCCAGGGTCAAACAACTACCCAAGG
ACAGAGCCAGGATTTGAACCAGGCCATCCAGTTCCAGAACCACTGCTCTTCACTGTCATTGTGGCCATTTTACAGTGCTCCTGCGGGAAG
AAGTGTCGCGGCTCCAGGAGGAAGTTCACCTTCTCCGGCAGATGAAGGAGATGTTGGCGAAGGACCTGGAGGAGTCGCAGGGCGGCAAGT
CCTCTGAGGTCCTCTCGGCCACCGAGCTCAGGGTCCAGCTGGCCCAGAAGGAGCAGGAGCTAGCCAGAGCCAAAGAAGCCTTGCAGGCTA
CAGCCTCCGCTTGGCGTCCCGATGCTCTCCACCAGCGGCCCCGTACATCACCAGGCAGTATAGGAAGGTCAAAGCTCCAGCTGCAGCCCA
GTTCCAGGGACCATTCTTCAAAGAGTAGACACTCTGGCTGCTCCCTGACAGCACCTGAAGTGACCTGGAATCAGTGAAGCCAAAGGGACT
GGCAGTCTGCCCTGCAGGGAGTACCGACCTATCCCAGTTGTGTGAGGCTGCGAGAGAAAGGGAGTGCATGTGCGCGCGTGCATGTGTGCG
TGCGTGTGTGTTCACGTGTTCTCGTGCGGGCGCGTGAGTGGTCTTCAAACGAGGGTCCCGATCCCCGGGGCGGCAGGAAGGGGGCCGACT
CCACGCTGTCCTTTGGGATGATACTTGGATGCAGCTCTTGGGACCGTGTTCTGCAGCCCAGCCTTCCTGTTGGGGTGGGGCCTCTCCTAC
TATGCAATTTTTCAAGAGCTCCTTGACCCTGCTTTTTGCTTCTTGAGTTGTCTTTTGCCATTATGGGGACTTTGGTTTGACCCAGGGGTC
AGCCTTAGGAAGGCCTTCAGGAGGAGGCCGAGTTCCCCTTCAGTACCACCCCTCTCTCCCCACCTTCCCTCTCCCGGCAACATCTCTGGG
AATCAACAGCATATTGACACGTTGGAGCCGAGCCTGAACATGCCCCTCGGCCCCAGCACATGGAAAACCCCCTTCCTTGCCTAAGGTGTC
TGAGTTTCTGGCTCTTGAGGCATTTCCAGACTTGAAATTCTCATCAGTCCATTGCTCTTGAGTCTTTGCAGAGAACCTCAGATCAGGTGC
ACCTGGGAGAAAGACTTTGTCCCCACTTACAGATCTATCTCCTCCCTTGGGAAGGGCAGGGAATGGGGACGGTGTATGGAGGGGAGGGAT
CTCCTGCGCCCTTCATTGCCACACTTGGTGGGACCATGAACATCTTTAGTGTCTGAGCTTCTCAAATTAGCTGCAATAGGAAAAAAACAA
ATTGGGAAATGAAAAAAAAATGGGAAGATTAAAAAGCACAGGGGGAAGAAGAAGAGATTTCGGAGGCCATCCTGCCAGGGGCGGACGGGG
CTGACTCCTGCTCTCTGGAGGACGGTCAGTCCATGTCTCGGAGAAACGGGTGAGCTGAGCTTGGCGTTTGGACCCAGTTCAGTGAGGTTC
TTGGGTTTTGTGCCTTTGGGGCAGACCCCAGGCAAGGATGTCTGAGACCACTTGGGCGCTGTTTTCTCAGCTCCAATTTCAAGAGTGAGC
TATCAAACCCAGAGCGGAAGGAGGGAGCTCTGATGAGCACGGTTTGTCACACGATAAAGGGATTTTTTTTTTCAGGGCTACTACGGTTGA
TCTTGCAACTCTGTAAATATGTATGTAGACACTTTTAAAAGCACGTATTTATGTCCCTGACTGTAAATGCTCCATTTTTAAAGTTTTATA
ACTTGTGTTATTTAATGAGTCAGTCAATCGGCTGCAGTATGGGATCTGATAAGGATCTAGGAGAAGGGTCTCATGCGGACCCTCACATGG
GCAGAAAAATGGTGGTCATTGGCCGACATCACAGTTTTCCTGTTTCCCACCCAGCTAAAAACCGTTGTTTGCTTTAAATTTTCATAAACT
GGAATCCTTTCACCCGCTCCTACAGCTAACCCTCACAAGCATGAAGTGCTGTGGCTGTTCCTTATCCTAATGATGCGCTTTTGTCCCGTA
AATGTTAACACTCATGAAGCATACCCCGGCCTCTCAGTTCTTGAGGGCCTCCCCACCGCAGCAGCAAGGAAAGCTCACGAACCCCAAACC
TGGCAAGTCACCTGCAGCCCATGGTGAGCTCTGGGAAGTGTGGTTGAGGCCTTGGGGTCACTCCTTTTTTGCATGTGCAAATGTGCTGGT
CACCCTTCAACGCTCCCAGACGGTCAGGAAAACTGTTCCAATCATGAAAAGGGGGGATGATTTTGTAAAAGTGGCATTTCCTGGTCAGTG

>41288_41288_3_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000400797_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=122AA_BP=
MPGVCPKGTKPKNLTELGPNAKLSSPVSPRHGLTVLQRAGVSPVRPWQDGLRNLFFFPLCFLIFPFFFHFPICFFPIAANLRSSDTKDVH

--------------------------------------------------------------
>41288_41288_4_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000400798_PRDM2_chr1_14142921_ENST00000376048_length(transcript)=2488nt_BP=437nt
GGGAGAGGGAAGGTCAGGCTTGCCTCCTGTTCACAAGGACAACCTCTGTCTCCCTTGTGGCGGCTTCTATGAAGGTGGGGACTCCAGGCT
TTCTCTCGTCTGCTTTTTGGATGCCTTCAAGAGAGGCCAGTTAGAGGATATCAATTGTGGCAATTCCCCAGAGCCCTCATCAGATGGCAT
TAGCCCGTCATGTGCTGCAGTGGCACCCAGTTTGGAGGAAATTCGGAACCAGAAGAGTGTGACAGTGCTCCTGCGGGAAGAAGTGTCGCG
GCTCCAGGAGGAAGTTCACCTTCTCCGGCAGATGAAGGAGATGTTGGCGAAGGACCTGGAGGAGTCGCAGGGCGGCAAGTCCTCTGAGGT
CCTCTCGGCCACCGAGCTCAGGGTCCAGCTGGCCCAGAAGGAGCAGGAGCTAGCCAGAGCCAAAGAAGCCTTGCAGGCTACAGCCTCCGC
TTGGCGTCCCGATGCTCTCCACCAGCGGCCCCGTACATCACCAGGCAGTATAGGAAGGTCAAAGCTCCAGCTGCAGCCCAGTTCCAGGGA
CCATTCTTCAAAGAGTAGACACTCTGGCTGCTCCCTGACAGCACCTGAAGTGACCTGGAATCAGTGAAGCCAAAGGGACTGGCAGTCTGC
CCTGCAGGGAGTACCGACCTATCCCAGTTGTGTGAGGCTGCGAGAGAAAGGGAGTGCATGTGCGCGCGTGCATGTGTGCGTGCGTGTGTG
TTCACGTGTTCTCGTGCGGGCGCGTGAGTGGTCTTCAAACGAGGGTCCCGATCCCCGGGGCGGCAGGAAGGGGGCCGACTCCACGCTGTC
CTTTGGGATGATACTTGGATGCAGCTCTTGGGACCGTGTTCTGCAGCCCAGCCTTCCTGTTGGGGTGGGGCCTCTCCTACTATGCAATTT
TTCAAGAGCTCCTTGACCCTGCTTTTTGCTTCTTGAGTTGTCTTTTGCCATTATGGGGACTTTGGTTTGACCCAGGGGTCAGCCTTAGGA
AGGCCTTCAGGAGGAGGCCGAGTTCCCCTTCAGTACCACCCCTCTCTCCCCACCTTCCCTCTCCCGGCAACATCTCTGGGAATCAACAGC
ATATTGACACGTTGGAGCCGAGCCTGAACATGCCCCTCGGCCCCAGCACATGGAAAACCCCCTTCCTTGCCTAAGGTGTCTGAGTTTCTG
GCTCTTGAGGCATTTCCAGACTTGAAATTCTCATCAGTCCATTGCTCTTGAGTCTTTGCAGAGAACCTCAGATCAGGTGCACCTGGGAGA
AAGACTTTGTCCCCACTTACAGATCTATCTCCTCCCTTGGGAAGGGCAGGGAATGGGGACGGTGTATGGAGGGGAGGGATCTCCTGCGCC
CTTCATTGCCACACTTGGTGGGACCATGAACATCTTTAGTGTCTGAGCTTCTCAAATTAGCTGCAATAGGAAAAAAACAAATTGGGAAAT
GAAAAAAAAATGGGAAGATTAAAAAGCACAGGGGGAAGAAGAAGAGATTTCGGAGGCCATCCTGCCAGGGGCGGACGGGGCTGACTCCTG
CTCTCTGGAGGACGGTCAGTCCATGTCTCGGAGAAACGGGTGAGCTGAGCTTGGCGTTTGGACCCAGTTCAGTGAGGTTCTTGGGTTTTG
TGCCTTTGGGGCAGACCCCAGGCAAGGATGTCTGAGACCACTTGGGCGCTGTTTTCTCAGCTCCAATTTCAAGAGTGAGCTATCAAACCC
AGAGCGGAAGGAGGGAGCTCTGATGAGCACGGTTTGTCACACGATAAAGGGATTTTTTTTTTCAGGGCTACTACGGTTGATCTTGCAACT
CTGTAAATATGTATGTAGACACTTTTAAAAGCACGTATTTATGTCCCTGACTGTAAATGCTCCATTTTTAAAGTTTTATAACTTGTGTTA
TTTAATGAGTCAGTCAATCGGCTGCAGTATGGGATCTGATAAGGATCTAGGAGAAGGGTCTCATGCGGACCCTCACATGGGCAGAAAAAT
GGTGGTCATTGGCCGACATCACAGTTTTCCTGTTTCCCACCCAGCTAAAAACCGTTGTTTGCTTTAAATTTTCATAAACTGGAATCCTTT
CACCCGCTCCTACAGCTAACCCTCACAAGCATGAAGTGCTGTGGCTGTTCCTTATCCTAATGATGCGCTTTTGTCCCGTAAATGTTAACA
CTCATGAAGCATACCCCGGCCTCTCAGTTCTTGAGGGCCTCCCCACCGCAGCAGCAAGGAAAGCTCACGAACCCCAAACCTGGCAAGTCA
CCTGCAGCCCATGGTGAGCTCTGGGAAGTGTGGTTGAGGCCTTGGGGTCACTCCTTTTTTGCATGTGCAAATGTGCTGGTCACCCTTCAA
CGCTCCCAGACGGTCAGGAAAACTGTTCCAATCATGAAAAGGGGGGATGATTTTGTAAAAGTGGCATTTCCTGGTCAGTGGTGGTCTTCA

>41288_41288_4_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000400798_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=195AA_BP=139
MPPVHKDNLCLPCGGFYEGGDSRLSLVCFLDAFKRGQLEDINCGNSPEPSSDGISPSCAAVAPSLEEIRNQKSVTVLLREEVSRLQEEVH
LLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQATASAWRPDALHQRPRTSPGSIGRSKLQLQPSSRDHSSKSR

--------------------------------------------------------------
>41288_41288_5_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000422387_PRDM2_chr1_14142921_ENST00000376048_length(transcript)=2750nt_BP=699nt
GGGGTCTCGGCGATCGCTGCTCCTCCTCCTCCTTCTCCTCCTCTTTTTTCTCCTCCGCCTCCTCCCCCCGCCGCCTCGCCACCGCCGCGG
CTAGGGCTGGAGGCGCCGCTGTCATTCCTGTGCCGGAGGAACCGGCGCTGCCGGTGCCTGGGGGTCGGGGCGCGGGCGAAGCCGGGCCGC
GGAGGACACAACAGGTAGAGCCGGGGGTGCCCGGCCGCGCGCCCCCCGCGCATCATGCAGCTCTTTGTCACCTCTCTCGCCCCCAGGCCA
AAATCCTGAGCATGATGGAAGACAATAAGCAGCTCGCGCTCCGCATCGATGGGGCGGTCCAGTCGGCCAGCCAGGAGGTGACCAACCTGC
GAGCCGAACTCACGGCCACCAACCGGAGACTGGCGGAACTGAGCGGCGGCGGCGGCCCCGGCCCGGGCCCGGGAGCCGCGGCCAGCGCCT
CGGCGGCGGGGGACTCGGCGGCGACGAACATGGAGAACCCCCAGCTTGGAGCGCAAGTGCTCCTGCGGGAAGAAGTGTCGCGGCTCCAGG
AGGAAGTTCACCTTCTCCGGCAGATGAAGGAGATGTTGGCGAAGGACCTGGAGGAGTCGCAGGGCGGCAAGTCCTCTGAGGTCCTCTCGG
CCACCGAGCTCAGGGTCCAGCTGGCCCAGAAGGAGCAGGAGCTAGCCAGAGCCAAAGAAGCCTTGCAGGCTACAGCCTCCGCTTGGCGTC
CCGATGCTCTCCACCAGCGGCCCCGTACATCACCAGGCAGTATAGGAAGGTCAAAGCTCCAGCTGCAGCCCAGTTCCAGGGACCATTCTT
CAAAGAGTAGACACTCTGGCTGCTCCCTGACAGCACCTGAAGTGACCTGGAATCAGTGAAGCCAAAGGGACTGGCAGTCTGCCCTGCAGG
GAGTACCGACCTATCCCAGTTGTGTGAGGCTGCGAGAGAAAGGGAGTGCATGTGCGCGCGTGCATGTGTGCGTGCGTGTGTGTTCACGTG
TTCTCGTGCGGGCGCGTGAGTGGTCTTCAAACGAGGGTCCCGATCCCCGGGGCGGCAGGAAGGGGGCCGACTCCACGCTGTCCTTTGGGA
TGATACTTGGATGCAGCTCTTGGGACCGTGTTCTGCAGCCCAGCCTTCCTGTTGGGGTGGGGCCTCTCCTACTATGCAATTTTTCAAGAG
CTCCTTGACCCTGCTTTTTGCTTCTTGAGTTGTCTTTTGCCATTATGGGGACTTTGGTTTGACCCAGGGGTCAGCCTTAGGAAGGCCTTC
AGGAGGAGGCCGAGTTCCCCTTCAGTACCACCCCTCTCTCCCCACCTTCCCTCTCCCGGCAACATCTCTGGGAATCAACAGCATATTGAC
ACGTTGGAGCCGAGCCTGAACATGCCCCTCGGCCCCAGCACATGGAAAACCCCCTTCCTTGCCTAAGGTGTCTGAGTTTCTGGCTCTTGA
GGCATTTCCAGACTTGAAATTCTCATCAGTCCATTGCTCTTGAGTCTTTGCAGAGAACCTCAGATCAGGTGCACCTGGGAGAAAGACTTT
GTCCCCACTTACAGATCTATCTCCTCCCTTGGGAAGGGCAGGGAATGGGGACGGTGTATGGAGGGGAGGGATCTCCTGCGCCCTTCATTG
CCACACTTGGTGGGACCATGAACATCTTTAGTGTCTGAGCTTCTCAAATTAGCTGCAATAGGAAAAAAACAAATTGGGAAATGAAAAAAA
AATGGGAAGATTAAAAAGCACAGGGGGAAGAAGAAGAGATTTCGGAGGCCATCCTGCCAGGGGCGGACGGGGCTGACTCCTGCTCTCTGG
AGGACGGTCAGTCCATGTCTCGGAGAAACGGGTGAGCTGAGCTTGGCGTTTGGACCCAGTTCAGTGAGGTTCTTGGGTTTTGTGCCTTTG
GGGCAGACCCCAGGCAAGGATGTCTGAGACCACTTGGGCGCTGTTTTCTCAGCTCCAATTTCAAGAGTGAGCTATCAAACCCAGAGCGGA
AGGAGGGAGCTCTGATGAGCACGGTTTGTCACACGATAAAGGGATTTTTTTTTTCAGGGCTACTACGGTTGATCTTGCAACTCTGTAAAT
ATGTATGTAGACACTTTTAAAAGCACGTATTTATGTCCCTGACTGTAAATGCTCCATTTTTAAAGTTTTATAACTTGTGTTATTTAATGA
GTCAGTCAATCGGCTGCAGTATGGGATCTGATAAGGATCTAGGAGAAGGGTCTCATGCGGACCCTCACATGGGCAGAAAAATGGTGGTCA
TTGGCCGACATCACAGTTTTCCTGTTTCCCACCCAGCTAAAAACCGTTGTTTGCTTTAAATTTTCATAAACTGGAATCCTTTCACCCGCT
CCTACAGCTAACCCTCACAAGCATGAAGTGCTGTGGCTGTTCCTTATCCTAATGATGCGCTTTTGTCCCGTAAATGTTAACACTCATGAA
GCATACCCCGGCCTCTCAGTTCTTGAGGGCCTCCCCACCGCAGCAGCAAGGAAAGCTCACGAACCCCAAACCTGGCAAGTCACCTGCAGC
CCATGGTGAGCTCTGGGAAGTGTGGTTGAGGCCTTGGGGTCACTCCTTTTTTGCATGTGCAAATGTGCTGGTCACCCTTCAACGCTCCCA
GACGGTCAGGAAAACTGTTCCAATCATGAAAAGGGGGGATGATTTTGTAAAAGTGGCATTTCCTGGTCAGTGGTGGTCTTCAAGACGACA

>41288_41288_5_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000422387_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=243AA_BP=187
MPVPGGRGAGEAGPRRTQQVEPGVPGRAPPAHHAALCHLSRPQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSG
GGGPGPGPGAAASASAAGDSAATNMENPQLGAQVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELA

--------------------------------------------------------------
>41288_41288_6_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000503743_PRDM2_chr1_14142921_ENST00000376048_length(transcript)=2678nt_BP=627nt
GGGGTCTCGGCGATCGCTGCTCCTCCTCCTCCTTCTCCTCCTCTTTTTTCTCCTCCGCCTCCTCCCCCCGCCGCCTCGCCACCGCCGCGG
CTAGGGCTGGAGGCGCCGCTGTCATTCCTGTGCCGGAGGAACCGGCGCTGCCGGTGCCTGGGGGTCGGGGCGCGGGCGAAGCCGGGCCGC
GGAGGACACAACAGGCCAAAATCCTGAGCATGATGGAAGACAATAAGCAGCTCGCGCTCCGCATCGATGGGGCGGTCCAGTCGGCCAGCC
AGGAGGTGACCAACCTGCGAGCCGAACTCACGGCCACCAACCGGAGACTGGCGGAACTGAGCGGCGGCGGCGGCCCCGGCCCGGGCCCGG
GAGCCGCGGCCAGCGCCTCGGCGGCGGGGGACTCGGCGGCGACGAACATGGAGAACCCCCAGCTTGGAGCGCAAGTGCTCCTGCGGGAAG
AAGTGTCGCGGCTCCAGGAGGAAGTTCACCTTCTCCGGCAGATGAAGGAGATGTTGGCGAAGGACCTGGAGGAGTCGCAGGGCGGCAAGT
CCTCTGAGGTCCTCTCGGCCACCGAGCTCAGGGTCCAGCTGGCCCAGAAGGAGCAGGAGCTAGCCAGAGCCAAAGAAGCCTTGCAGGCTA
CAGCCTCCGCTTGGCGTCCCGATGCTCTCCACCAGCGGCCCCGTACATCACCAGGCAGTATAGGAAGGTCAAAGCTCCAGCTGCAGCCCA
GTTCCAGGGACCATTCTTCAAAGAGTAGACACTCTGGCTGCTCCCTGACAGCACCTGAAGTGACCTGGAATCAGTGAAGCCAAAGGGACT
GGCAGTCTGCCCTGCAGGGAGTACCGACCTATCCCAGTTGTGTGAGGCTGCGAGAGAAAGGGAGTGCATGTGCGCGCGTGCATGTGTGCG
TGCGTGTGTGTTCACGTGTTCTCGTGCGGGCGCGTGAGTGGTCTTCAAACGAGGGTCCCGATCCCCGGGGCGGCAGGAAGGGGGCCGACT
CCACGCTGTCCTTTGGGATGATACTTGGATGCAGCTCTTGGGACCGTGTTCTGCAGCCCAGCCTTCCTGTTGGGGTGGGGCCTCTCCTAC
TATGCAATTTTTCAAGAGCTCCTTGACCCTGCTTTTTGCTTCTTGAGTTGTCTTTTGCCATTATGGGGACTTTGGTTTGACCCAGGGGTC
AGCCTTAGGAAGGCCTTCAGGAGGAGGCCGAGTTCCCCTTCAGTACCACCCCTCTCTCCCCACCTTCCCTCTCCCGGCAACATCTCTGGG
AATCAACAGCATATTGACACGTTGGAGCCGAGCCTGAACATGCCCCTCGGCCCCAGCACATGGAAAACCCCCTTCCTTGCCTAAGGTGTC
TGAGTTTCTGGCTCTTGAGGCATTTCCAGACTTGAAATTCTCATCAGTCCATTGCTCTTGAGTCTTTGCAGAGAACCTCAGATCAGGTGC
ACCTGGGAGAAAGACTTTGTCCCCACTTACAGATCTATCTCCTCCCTTGGGAAGGGCAGGGAATGGGGACGGTGTATGGAGGGGAGGGAT
CTCCTGCGCCCTTCATTGCCACACTTGGTGGGACCATGAACATCTTTAGTGTCTGAGCTTCTCAAATTAGCTGCAATAGGAAAAAAACAA
ATTGGGAAATGAAAAAAAAATGGGAAGATTAAAAAGCACAGGGGGAAGAAGAAGAGATTTCGGAGGCCATCCTGCCAGGGGCGGACGGGG
CTGACTCCTGCTCTCTGGAGGACGGTCAGTCCATGTCTCGGAGAAACGGGTGAGCTGAGCTTGGCGTTTGGACCCAGTTCAGTGAGGTTC
TTGGGTTTTGTGCCTTTGGGGCAGACCCCAGGCAAGGATGTCTGAGACCACTTGGGCGCTGTTTTCTCAGCTCCAATTTCAAGAGTGAGC
TATCAAACCCAGAGCGGAAGGAGGGAGCTCTGATGAGCACGGTTTGTCACACGATAAAGGGATTTTTTTTTTCAGGGCTACTACGGTTGA
TCTTGCAACTCTGTAAATATGTATGTAGACACTTTTAAAAGCACGTATTTATGTCCCTGACTGTAAATGCTCCATTTTTAAAGTTTTATA
ACTTGTGTTATTTAATGAGTCAGTCAATCGGCTGCAGTATGGGATCTGATAAGGATCTAGGAGAAGGGTCTCATGCGGACCCTCACATGG
GCAGAAAAATGGTGGTCATTGGCCGACATCACAGTTTTCCTGTTTCCCACCCAGCTAAAAACCGTTGTTTGCTTTAAATTTTCATAAACT
GGAATCCTTTCACCCGCTCCTACAGCTAACCCTCACAAGCATGAAGTGCTGTGGCTGTTCCTTATCCTAATGATGCGCTTTTGTCCCGTA
AATGTTAACACTCATGAAGCATACCCCGGCCTCTCAGTTCTTGAGGGCCTCCCCACCGCAGCAGCAAGGAAAGCTCACGAACCCCAAACC
TGGCAAGTCACCTGCAGCCCATGGTGAGCTCTGGGAAGTGTGGTTGAGGCCTTGGGGTCACTCCTTTTTTGCATGTGCAAATGTGCTGGT
CACCCTTCAACGCTCCCAGACGGTCAGGAAAACTGTTCCAATCATGAAAAGGGGGGATGATTTTGTAAAAGTGGCATTTCCTGGTCAGTG

>41288_41288_6_KAZN-PRDM2_KAZN_chr1_15287371_ENST00000503743_PRDM2_chr1_14142921_ENST00000376048_length(amino acids)=219AA_BP=163
MPVPGGRGAGEAGPRRTQQAKILSMMEDNKQLALRIDGAVQSASQEVTNLRAELTATNRRLAELSGGGGPGPGPGAAASASAAGDSAATN
MENPQLGAQVLLREEVSRLQEEVHLLRQMKEMLAKDLEESQGGKSSEVLSATELRVQLAQKEQELARAKEALQATASAWRPDALHQRPRT

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Fusion Gene PPI Analysis for KAZN-PRDM2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneKAZNchr1:15287371chr1:14142921ENST00000361144+28174_333133.33333333333334416.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000376030+215174_333139.33333333333334776.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000400797+28174_33345.333333333333336328.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000400798+28174_33345.333333333333336328.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000422387+28174_333139.33333333333334422.0PPL
HgeneKAZNchr1:15287371chr1:14142921ENST00000503743+39174_333139.33333333333334422.0PPL


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KAZN-PRDM2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KAZN-PRDM2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource