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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KIAA0319L-CLSPN (FusionGDB2 ID:42090)

Fusion Gene Summary for KIAA0319L-CLSPN

check button Fusion gene summary
Fusion gene informationFusion gene name: KIAA0319L-CLSPN
Fusion gene ID: 42090
HgeneTgene
Gene symbol

KIAA0319L

CLSPN

Gene ID

79932

63967

Gene nameKIAA0319 likeclaspin
SynonymsAAVR|AAVRL-
Cytomap

1p34.3

1p34.3

Type of geneprotein-codingprotein-coding
Descriptiondyslexia-associated protein KIAA0319-like proteinAAV receptorAAV receptor likeadeno-associated virus receptorpolycystic kidney disease 1-relatedclaspinclaspin homolog
Modification date2020031320200322
UniProtAcc

Q8IZA0

Q9HAW4

Ensembl transtripts involved in fusion geneENST00000325722, ENST00000485551, 
ENST00000373266, 		ENST00000318121, 
ENST00000373220, ENST00000466308, 
ENST00000520551, ENST00000251195, 
Fusion gene scores* DoF score19 X 14 X 13=34586 X 7 X 6=252
# samples 288
** MAII scorelog2(28/3458*10)=-3.62643913669732
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/252*10)=-1.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KIAA0319L [Title/Abstract] AND CLSPN [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKIAA0319L(35936464)-CLSPN(36230927), # samples:2
Anticipated loss of major functional domain due to fusion event.KIAA0319L-CLSPN seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
KIAA0319L-CLSPN seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCLSPN

GO:0000076

DNA replication checkpoint

12766152

TgeneCLSPN

GO:0007095

mitotic G2 DNA damage checkpoint

18662541

TgeneCLSPN

GO:0018105

peptidyl-serine phosphorylation

16885022

TgeneCLSPN

GO:0032147

activation of protein kinase activity

16885022


check buttonFusion gene breakpoints across KIAA0319L (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CLSPN (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LIHCTCGA-5C-A9VG-01AKIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
ChimerDB4LUSCTCGA-66-2737-01AKIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
ChimerDB4STADTCGA-BR-A4QI-01AKIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
ChimerDB4STADTCGA-BR-A4QI-01AKIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-


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Fusion Gene ORF analysis for KIAA0319L-CLSPN

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000325722ENST00000318121KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
5CDS-intronENST00000325722ENST00000318121KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
5CDS-intronENST00000325722ENST00000318121KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
5CDS-intronENST00000325722ENST00000318121KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
5CDS-intronENST00000325722ENST00000373220KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
5CDS-intronENST00000325722ENST00000373220KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
5CDS-intronENST00000325722ENST00000373220KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
5CDS-intronENST00000325722ENST00000373220KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
5CDS-intronENST00000325722ENST00000466308KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
5CDS-intronENST00000325722ENST00000466308KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
5CDS-intronENST00000325722ENST00000466308KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
5CDS-intronENST00000325722ENST00000466308KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
5CDS-intronENST00000325722ENST00000520551KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
5CDS-intronENST00000325722ENST00000520551KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
5CDS-intronENST00000325722ENST00000520551KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
5CDS-intronENST00000325722ENST00000520551KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
5UTR-3CDSENST00000485551ENST00000251195KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
5UTR-intronENST00000485551ENST00000318121KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
5UTR-intronENST00000485551ENST00000373220KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
5UTR-intronENST00000485551ENST00000466308KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
5UTR-intronENST00000485551ENST00000520551KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
Frame-shiftENST00000325722ENST00000251195KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
Frame-shiftENST00000325722ENST00000251195KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
Frame-shiftENST00000325722ENST00000251195KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
In-frameENST00000325722ENST00000251195KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-3CDSENST00000373266ENST00000251195KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
intron-3CDSENST00000373266ENST00000251195KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-3CDSENST00000373266ENST00000251195KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-3CDSENST00000373266ENST00000251195KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
intron-3CDSENST00000485551ENST00000251195KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-3CDSENST00000485551ENST00000251195KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-3CDSENST00000485551ENST00000251195KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
intron-intronENST00000373266ENST00000318121KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
intron-intronENST00000373266ENST00000318121KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-intronENST00000373266ENST00000318121KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-intronENST00000373266ENST00000318121KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
intron-intronENST00000373266ENST00000373220KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
intron-intronENST00000373266ENST00000373220KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-intronENST00000373266ENST00000373220KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-intronENST00000373266ENST00000373220KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
intron-intronENST00000373266ENST00000466308KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
intron-intronENST00000373266ENST00000466308KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-intronENST00000373266ENST00000466308KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-intronENST00000373266ENST00000466308KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
intron-intronENST00000373266ENST00000520551KIAA0319Lchr1

35936464

-CLSPNchr1

36230927

-
intron-intronENST00000373266ENST00000520551KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-intronENST00000373266ENST00000520551KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-intronENST00000373266ENST00000520551KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
intron-intronENST00000485551ENST00000318121KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-intronENST00000485551ENST00000318121KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-intronENST00000485551ENST00000318121KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
intron-intronENST00000485551ENST00000373220KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-intronENST00000485551ENST00000373220KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-intronENST00000485551ENST00000373220KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
intron-intronENST00000485551ENST00000466308KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-intronENST00000485551ENST00000466308KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-intronENST00000485551ENST00000466308KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-
intron-intronENST00000485551ENST00000520551KIAA0319Lchr1

36019950

-CLSPNchr1

36204994

+
intron-intronENST00000485551ENST00000520551KIAA0319Lchr1

36019951

-CLSPNchr1

36219537

-
intron-intronENST00000485551ENST00000520551KIAA0319Lchr1

36019951

-CLSPNchr1

36228922

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000325722KIAA0319Lchr136019950-ENST00000251195CLSPNchr136204994+177037710411448135

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000325722ENST00000251195KIAA0319Lchr136019950-CLSPNchr136204994+0.032087320.9679127

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Fusion Genomic Features for KIAA0319L-CLSPN


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KIAA0319L-CLSPN


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:35936464/chr1:36230927)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KIAA0319L

Q8IZA0

CLSPN

Q9HAW4

FUNCTION: Possible role in axon guidance through interaction with RTN4R. {ECO:0000269|PubMed:20697954}.; FUNCTION: (Microbial infection) Acts as a receptor for adeno-associated virus and is involved in adeno-associated virus infection through endocytosis system. {ECO:0000269|PubMed:26814968}.FUNCTION: Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR-dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S-phase chromatin following formation of the pre-replication complex (pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks. {ECO:0000269|PubMed:12766152, ECO:0000269|PubMed:15096610, ECO:0000269|PubMed:15190204, ECO:0000269|PubMed:15226314, ECO:0000269|PubMed:15707391}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-2211_29471050.0Topological domainCytoplasmic
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-22130_50471050.0TransmembraneHelical
TgeneCLSPNchr1:36019950chr1:36204994ENST00000251195025162_19601333.0Coiled coilOntology_term=ECO:0000255
TgeneCLSPNchr1:36019950chr1:36204994ENST00000251195025592_68101333.0Coiled coilOntology_term=ECO:0000255
TgeneCLSPNchr1:36019950chr1:36204994ENST00000318121025162_19601340.0Coiled coilOntology_term=ECO:0000255
TgeneCLSPNchr1:36019950chr1:36204994ENST00000318121025592_68101340.0Coiled coilOntology_term=ECO:0000255
TgeneCLSPNchr1:36019950chr1:36204994ENST00000373220024162_19601276.0Coiled coilOntology_term=ECO:0000255
TgeneCLSPNchr1:36019950chr1:36204994ENST00000373220024592_68101276.0Coiled coilOntology_term=ECO:0000255
TgeneCLSPNchr1:36019950chr1:36204994ENST00000251195025910_91901333.0RepeatNote=CKB motif 1
TgeneCLSPNchr1:36019950chr1:36204994ENST00000251195025939_94801333.0RepeatNote=CKB motif 2
TgeneCLSPNchr1:36019950chr1:36204994ENST00000251195025976_98501333.0RepeatNote=CKB motif 3
TgeneCLSPNchr1:36019950chr1:36204994ENST00000318121025910_91901340.0RepeatNote=CKB motif 1
TgeneCLSPNchr1:36019950chr1:36204994ENST00000318121025939_94801340.0RepeatNote=CKB motif 2
TgeneCLSPNchr1:36019950chr1:36204994ENST00000318121025976_98501340.0RepeatNote=CKB motif 3
TgeneCLSPNchr1:36019950chr1:36204994ENST00000373220024910_91901276.0RepeatNote=CKB motif 1
TgeneCLSPNchr1:36019950chr1:36204994ENST00000373220024939_94801276.0RepeatNote=CKB motif 2
TgeneCLSPNchr1:36019950chr1:36204994ENST00000373220024976_98501276.0RepeatNote=CKB motif 3

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-221312_401471050.0DomainPKD 1
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-221409_498471050.0DomainPKD 2
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-22149_127471050.0DomainMANSC
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-221504_594471050.0DomainPKD 3
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-221600_688471050.0DomainPKD 4
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-221694_785471050.0DomainPKD 5
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-22151_932471050.0Topological domainExtracellular
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-221954_1049471050.0Topological domainCytoplasmic
HgeneKIAA0319Lchr1:36019950chr1:36204994ENST00000325722-221933_953471050.0TransmembraneHelical


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Fusion Gene Sequence for KIAA0319L-CLSPN


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42090_42090_1_KIAA0319L-CLSPN_KIAA0319L_chr1_36019950_ENST00000325722_CLSPN_chr1_36204994_ENST00000251195_length(transcript)=1770nt_BP=377nt
AGGAGGCGGTGTTTCCGGCCGCCGTCGCTGTCCAGGGAGGCTGAGGCGAGAGGTAGCTGTCCGGGTGGGGAGCCCGCACTACCTTCTTCC
TCTTCCTCCTCCTCCTCCGGGTGAGGGGAGCGAAGGTTGGGGGTCCCCGAGCCCATGGACCAGGAGGAGGCGGAGGCCGCCGAGAGCCGG
GGCCCCGCTATGTGGCCCTGAGCCCCGTGTACTGGTTCTGCCTGTCTGGAGGGCCATGGAGAAGAGGCTGGGAGTCAAGCCAAATCCTGC
TTCCTGGATTTTATCAGGATATTATTGGCAGACATCTGCGAAGTGGTTGAGAAGCCTGTACCTGTTTTATACTTGCTTTTGCTTCAGCGT
TCTGTGGTTGTCAACAGAAGATCCCAGAGAAGGACTCTGACTGGCTCACCTGGAGTGGAGCTCCTATCCCTGGATTCTTCAGGCTTTCAT
TTGACCCACATGGTTAAGCTGGGAGAGACAGAGTCCAAAGAGAGGCGGAGAAGGGCTATTCTGGGCAGAACAAACAATTGATGACTTTAT
GGCTCTGTGGTCTGGGCAGAACTGCATAACCCTAGATCACCAAAGCTGAGAGCCTTTAGGAGTGAGGATTTGGGCCAGGCATGGTGGCTC
ACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGTGGGTGGATCACAAGGTCAGGAGATCAAGACCAACCTGACCAACATGGTGAAACCC
CATCTCTACTAAAAATACAAAAATTAGCTGACGTGATGCATGCACCTGTAATCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTG
AACCCGGGAGGTGGAGGTTGCGGTGAGCCGAGATTGCGCCACTGCACTCCAGCCTAGGCGACAGAGCGAGACTCCATCTCAAAAAAAAAA
AAAAAAAAAAAAAAAGTGAGGATTTGGGTCACCCCAGGCTGAAGGCCAGGGGAACCTGAAGTGGATAAGGGAAGGGAGAAGACTTAGGCC
ACAGGATCTGATGTAGAAATGGGGCTGACGTCTCCACCTGTATTTTCTTAGCTGGAGGAGTGTGCAAAGTTTGAATTACTTCTGCCTTCT
CCTTCTTATTTCCTTTTCCCTTTTAAAATAGTCATCATAATCATAAAAATTTCTTTTCCAGTGAAGACAGGCTCACTGCTAAACCAGCCC
AAAGCTGTGCTTCAGAAACTGGCTGCTCTCTCTGACCATAACCCCAGTGCTCCTCGAAATTCAAGAAACTTTGTCTTTCATACACTTTCT
CCTGTCAAGGCTGAGGCGGCAAAGGAATCGTCTAAGTCTCAGCCAGTCGCCCTATGGTTATTCAGGAATCAAAGTCTTTGCTCAGAAATC
CTTTTGAAGCCATCAGACCAGGAAGTGCTCAACAGGCACAGCAGGGGAAAATTACAGCTGAAGAAGAAGAAGAAATTGGGGAGGACAGTC
AGTTTATGATACTGGCCAAGAAAGTTACAGCCAAAGCACTGCAGAAGAATGATGATGCTTCCCAGATGGACTTGTTCCACAGAGACTCTG
ATGATGATCAGACTGAAGAACAGCTTGATGAGTCAGAAGCCAGGTGGAGGAAGGAGCGAATTGAACGAGAGCAGTGGCTTCGGGACATGG
AAAACTATGTTGGATGATGATAAGCGACAGCTACGTTTATACCAAGAGAGGTACCTTGCTGATGGGGATCTGCACAGCGATGGTCCTGGG

>42090_42090_1_KIAA0319L-CLSPN_KIAA0319L_chr1_36019950_ENST00000325722_CLSPN_chr1_36204994_ENST00000251195_length(amino acids)=135AA_BP=
MEECAKFELLLPSPSYFLFPFKIVIIIIKISFPVKTGSLLNQPKAVLQKLAALSDHNPSAPRNSRNFVFHTLSPVKAEAAKESSKSQPVA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for KIAA0319L-CLSPN


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KIAA0319L-CLSPN


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KIAA0319L-CLSPN


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource