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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KIAA0586-SLC38A6 (FusionGDB2 ID:42158)

Fusion Gene Summary for KIAA0586-SLC38A6

check button Fusion gene summary
Fusion gene informationFusion gene name: KIAA0586-SLC38A6
Fusion gene ID: 42158
HgeneTgene
Gene symbol

KIAA0586

SLC38A6

Gene ID

9786

145389

Gene nameKIAA0586solute carrier family 38 member 6
SynonymsJBTS23|SRTD14|Talpid3NAT-1|SNAT6
Cytomap

14q23.1

14q23.1

Type of geneprotein-codingprotein-coding
Descriptionprotein TALPID3probable sodium-coupled neutral amino acid transporter 6N system amino acid transporter NAT-1N-system amino acid transporter 1Na(+)-coupled neutral amino acid transporter 6
Modification date2020032020200313
UniProtAcc

Q9BVV6

Q8IZM9

Ensembl transtripts involved in fusion geneENST00000261244, ENST00000354386, 
ENST00000423743, ENST00000556134, 
ENST00000538571, 		ENST00000554304, 
ENST00000267488, ENST00000354886, 
ENST00000456840, 
Fusion gene scores* DoF score5 X 5 X 4=1004 X 4 X 3=48
# samples 65
** MAII scorelog2(6/100*10)=-0.736965594166206
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: KIAA0586 [Title/Abstract] AND SLC38A6 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKIAA0586(58899175)-SLC38A6(61512785), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across KIAA0586 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC38A6 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-BR-A4PD-01AKIAA0586chr14

58899175

+SLC38A6chr14

61512785

+


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Fusion Gene ORF analysis for KIAA0586-SLC38A6

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000261244ENST00000554304KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
5CDS-intronENST00000354386ENST00000554304KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
5CDS-intronENST00000423743ENST00000554304KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
5CDS-intronENST00000556134ENST00000554304KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000261244ENST00000267488KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000261244ENST00000354886KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000261244ENST00000456840KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000354386ENST00000267488KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000354386ENST00000354886KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000354386ENST00000456840KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000423743ENST00000267488KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000423743ENST00000354886KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000423743ENST00000456840KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000556134ENST00000267488KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000556134ENST00000354886KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
In-frameENST00000556134ENST00000456840KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
intron-3CDSENST00000538571ENST00000267488KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
intron-3CDSENST00000538571ENST00000354886KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
intron-3CDSENST00000538571ENST00000456840KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+
intron-intronENST00000538571ENST00000554304KIAA0586chr14

58899175

+SLC38A6chr14

61512785

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000354386KIAA0586chr1458899175+ENST00000354886SLC38A6chr1461512785+14526902441431395
ENST00000354386KIAA0586chr1458899175+ENST00000267488SLC38A6chr1461512785+14386902441236330
ENST00000354386KIAA0586chr1458899175+ENST00000456840SLC38A6chr1461512785+14576902441398384
ENST00000556134KIAA0586chr1458899175+ENST00000354886SLC38A6chr1461512785+14016391691380403
ENST00000556134KIAA0586chr1458899175+ENST00000267488SLC38A6chr1461512785+13876391691185338
ENST00000556134KIAA0586chr1458899175+ENST00000456840SLC38A6chr1461512785+14066391691347392
ENST00000423743KIAA0586chr1458899175+ENST00000354886SLC38A6chr1461512785+11754131351154339
ENST00000423743KIAA0586chr1458899175+ENST00000267488SLC38A6chr1461512785+1161413135959274
ENST00000423743KIAA0586chr1458899175+ENST00000456840SLC38A6chr1461512785+11804131351121328
ENST00000261244KIAA0586chr1458899175+ENST00000354886SLC38A6chr1461512785+14476852751426383
ENST00000261244KIAA0586chr1458899175+ENST00000267488SLC38A6chr1461512785+14336852751231318
ENST00000261244KIAA0586chr1458899175+ENST00000456840SLC38A6chr1461512785+14526852751393372

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000354386ENST00000354886KIAA0586chr1458899175+SLC38A6chr1461512785+0.0024656040.9975344
ENST00000354386ENST00000267488KIAA0586chr1458899175+SLC38A6chr1461512785+0.0017781330.9982218
ENST00000354386ENST00000456840KIAA0586chr1458899175+SLC38A6chr1461512785+0.0014984970.99850154
ENST00000556134ENST00000354886KIAA0586chr1458899175+SLC38A6chr1461512785+0.001465470.99853456
ENST00000556134ENST00000267488KIAA0586chr1458899175+SLC38A6chr1461512785+0.0013946790.9986053
ENST00000556134ENST00000456840KIAA0586chr1458899175+SLC38A6chr1461512785+0.0007642330.99923575
ENST00000423743ENST00000354886KIAA0586chr1458899175+SLC38A6chr1461512785+0.0030977630.9969022
ENST00000423743ENST00000267488KIAA0586chr1458899175+SLC38A6chr1461512785+0.0026380660.99736196
ENST00000423743ENST00000456840KIAA0586chr1458899175+SLC38A6chr1461512785+0.0014595940.9985404
ENST00000261244ENST00000354886KIAA0586chr1458899175+SLC38A6chr1461512785+0.0015841690.9984158
ENST00000261244ENST00000267488KIAA0586chr1458899175+SLC38A6chr1461512785+0.0014803920.9985196
ENST00000261244ENST00000456840KIAA0586chr1458899175+SLC38A6chr1461512785+0.0010012490.9989987

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Fusion Genomic Features for KIAA0586-SLC38A6


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KIAA0586chr1458899175+SLC38A6chr1461512784+0.0008936860.99910635
KIAA0586chr1458899175+SLC38A6chr1461512784+0.0008936860.99910635

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for KIAA0586-SLC38A6


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr14:58899175/chr14:61512785)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KIAA0586

Q9BVV6

SLC38A6

Q8IZM9

FUNCTION: Required for ciliogenesis and sonic hedgehog/SHH signaling. Required for the centrosomal recruitment of RAB8A and for the targeting of centriole satellite proteins to centrosomes such as of PCM1. May play a role in early ciliogenesis in the disappearance of centriolar satellites that preceeds ciliary vesicle formation (PubMed:24421332). Involved in regulation of cell intracellular organization. Involved in regulation of cell polarity (By similarity). Required for asymmetrical localization of CEP120 to daughter centrioles (By similarity). {ECO:0000250|UniProtKB:E9PV87, ECO:0000250|UniProtKB:Q1G7G9, ECO:0000269|PubMed:24421332}.FUNCTION: Probable sodium-dependent amino acid/proton antiporter, could be a neuronal transporter for glutamate. {ECO:0000250|UniProtKB:G3UVW3}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneSLC38A6chr14:58899175chr14:61512785ENST000002674881016288_308274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000002674881016327_347274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000002674881016371_391274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000002674881016394_414274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000002674881016431_451274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000003548861017288_308274522.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000003548861017327_347274522.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000003548861017371_391274522.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000003548861017394_414274522.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000003548861017431_451274522.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000261244+430182_2231361473.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000261244+430467_5011361473.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000354386+534182_2231481645.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000354386+534467_5011481645.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000423743+432182_223511505.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000423743+432467_501511505.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000556134+532182_2231211534.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000556134+532467_5011211534.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000261244+4301180_11871361473.0Compositional biasNote=Poly-Pro
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000261244+430247_2501361473.0Compositional biasNote=Poly-Gln
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000354386+5341180_11871481645.0Compositional biasNote=Poly-Pro
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000354386+534247_2501481645.0Compositional biasNote=Poly-Gln
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000423743+4321180_1187511505.0Compositional biasNote=Poly-Pro
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000423743+432247_250511505.0Compositional biasNote=Poly-Gln
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000556134+5321180_11871211534.0Compositional biasNote=Poly-Pro
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000556134+532247_2501211534.0Compositional biasNote=Poly-Gln
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000261244+430467_5541361473.0RegionRequired for centrosomal localization
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000354386+534467_5541481645.0RegionRequired for centrosomal localization
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000423743+432467_554511505.0RegionRequired for centrosomal localization
HgeneKIAA0586chr14:58899175chr14:61512785ENST00000556134+532467_5541211534.0RegionRequired for centrosomal localization
TgeneSLC38A6chr14:58899175chr14:61512785ENST000002674881016111_131274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000002674881016170_190274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000002674881016191_211274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000002674881016250_270274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST00000267488101642_62274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST00000267488101685_105274457.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000003548861017111_131274522.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000003548861017170_190274522.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000003548861017191_211274522.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST000003548861017250_270274522.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST00000354886101742_62274522.0TransmembraneHelical
TgeneSLC38A6chr14:58899175chr14:61512785ENST00000354886101785_105274522.0TransmembraneHelical


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Fusion Gene Sequence for KIAA0586-SLC38A6


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42158_42158_1_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000261244_SLC38A6_chr14_61512785_ENST00000267488_length(transcript)=1433nt_BP=685nt
GGTTATTGTTGCTCCTGTGGCCATTCTCTTGTCATCCCCACTTTCACATTTTGGCGTGGTGTATTAATAGACTGAGTGGGATTAATGGGT
AAATATGACTTTATAGTCAGCTCTAATCCTGGATTCAATATCAGAATTTAGATTTTCAGCTTTGTGGATGTTCGACATTTTAAAAACAGT
TATTGCAAAGAGGTGAAAATTTTGTTCTGAAGTCTTAAGGAAACAGAGAAAGTTTTTCCGTCCTTAAGTGTGGGACTTGTTTTGTGACCA
ACAATATGAAAGGCTCTGAGGTCAGCTTGGAGAAGAAAAAAAAGATTAAGATGCCAGTGAAGAGACTTCGTGAGGTAGTTTCTCAAAATC
ATGGAGATCATTTGGTTTTGCTGAAAGATGAGTTGCCCTGTGTTCCTCCGGCATTGTCTGCAAATAAACGTCTTCCTGTTGGAACGGGGA
CTAGTTTGAATGGAACATCACGTGGTTCATCAGACTTAACTTCTGCTAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGTGTCAG
AAAGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGATAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACATCTTCA
TTTCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTTAAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTACCAATA
CAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAA
AAGGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCCTCTAA
TCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCAC
TCAATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATGTTTGA
TTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGATTTTCTGTCATGGAAAAAGCTTGGGGCATTCGTTTTGCTCATCT
TTGGAATTTTGGTTGGGAATTTTAGTTTAGCACTCATCATTTTTGATTGGATTAATAAATAAAAGAAATATTTTCCTACTTCTTACAAGA
ATAATATACCCCTAGTTGCAAGAATGAATTATTCCGGAAGACACCCTGGATGAAAAATAACATTTTAATAAAAATTATTAACAGAAAAGC

>42158_42158_1_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000261244_SLC38A6_chr14_61512785_ENST00000267488_length(amino acids)=318AA_BP=0
MKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSDLTSARNCYQPLLENPMVSES
DFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLKQNPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKG
YSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIF

--------------------------------------------------------------
>42158_42158_2_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000261244_SLC38A6_chr14_61512785_ENST00000354886_length(transcript)=1447nt_BP=685nt
GGTTATTGTTGCTCCTGTGGCCATTCTCTTGTCATCCCCACTTTCACATTTTGGCGTGGTGTATTAATAGACTGAGTGGGATTAATGGGT
AAATATGACTTTATAGTCAGCTCTAATCCTGGATTCAATATCAGAATTTAGATTTTCAGCTTTGTGGATGTTCGACATTTTAAAAACAGT
TATTGCAAAGAGGTGAAAATTTTGTTCTGAAGTCTTAAGGAAACAGAGAAAGTTTTTCCGTCCTTAAGTGTGGGACTTGTTTTGTGACCA
ACAATATGAAAGGCTCTGAGGTCAGCTTGGAGAAGAAAAAAAAGATTAAGATGCCAGTGAAGAGACTTCGTGAGGTAGTTTCTCAAAATC
ATGGAGATCATTTGGTTTTGCTGAAAGATGAGTTGCCCTGTGTTCCTCCGGCATTGTCTGCAAATAAACGTCTTCCTGTTGGAACGGGGA
CTAGTTTGAATGGAACATCACGTGGTTCATCAGACTTAACTTCTGCTAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGTGTCAG
AAAGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGATAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACATCTTCA
TTTCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTTAAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTACCAATA
CAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAA
AAGGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCCTCTAA
TCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCAC
TCAATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATGTTTGA
TTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGATTTTCTGTCATGGAAAAAGCTTGGGGGTCTCATTCTGTCGCACA
GGTTGGCGTGCAGTGGTGTGATCTCAGCTCATTGCAACCTCTGCCTCCCGGACTCAAGCAATCCTCCCACCTCAGCCTCCAGAGTAGCTG
AGACTACAGGAAGAGATACCATGGAGATGTGCACCCAGAGGAAAGGCCACGCAAGGACACAGCAAGAAGGCAACTGTTTACAAGCCAAGG
GAAGAGGCCTCAGGAGAACCAAACGTGTCCACACCTTGATCTTGCACTTCCCAACCTCCAGAACTGTGAGCAAATAAATGATGTTGTTTA

>42158_42158_2_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000261244_SLC38A6_chr14_61512785_ENST00000354886_length(amino acids)=383AA_BP=0
MKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSDLTSARNCYQPLLENPMVSES
DFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLKQNPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKG
YSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIF
IFPGLFYLKLSREDFLSWKKLGGLILSHRLACSGVISAHCNLCLPDSSNPPTSASRVAETTGRDTMEMCTQRKGHARTQQEGNCLQAKGR

--------------------------------------------------------------
>42158_42158_3_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000261244_SLC38A6_chr14_61512785_ENST00000456840_length(transcript)=1452nt_BP=685nt
GGTTATTGTTGCTCCTGTGGCCATTCTCTTGTCATCCCCACTTTCACATTTTGGCGTGGTGTATTAATAGACTGAGTGGGATTAATGGGT
AAATATGACTTTATAGTCAGCTCTAATCCTGGATTCAATATCAGAATTTAGATTTTCAGCTTTGTGGATGTTCGACATTTTAAAAACAGT
TATTGCAAAGAGGTGAAAATTTTGTTCTGAAGTCTTAAGGAAACAGAGAAAGTTTTTCCGTCCTTAAGTGTGGGACTTGTTTTGTGACCA
ACAATATGAAAGGCTCTGAGGTCAGCTTGGAGAAGAAAAAAAAGATTAAGATGCCAGTGAAGAGACTTCGTGAGGTAGTTTCTCAAAATC
ATGGAGATCATTTGGTTTTGCTGAAAGATGAGTTGCCCTGTGTTCCTCCGGCATTGTCTGCAAATAAACGTCTTCCTGTTGGAACGGGGA
CTAGTTTGAATGGAACATCACGTGGTTCATCAGACTTAACTTCTGCTAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGTGTCAG
AAAGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGATAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACATCTTCA
TTTCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTTAAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTACCAATA
CAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAA
AAGGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCCTCTAA
TCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCAC
TCAATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATGTTTGA
TTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGATTTTCTGTCATGGAAAAAGCTTGGGGGTCTCATTCTGTCGCACA
GGTTGGCGTGCAGTGGTGTGATCTCAGCTCATTGCAACCTCTGCCTCCCGGACTCAAGCAATCCTCCCACCTCAGCCTCCAGAGTAGCTG
AGACTACAGAAAAGGAAGAGATACCATGGAGATGTGCACCCAGAGGAAAGGCCACGCAAGGACACAGCAAGAAGGCAACTGTTTACAAGC
CAAGGGAAGAGGCCTCAGGAGAACCAAACGTGTCCACACCTTGATCTTGCACTTCCCAACCTCCAGAACTGTGAGCAAATAAATGATGTT

>42158_42158_3_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000261244_SLC38A6_chr14_61512785_ENST00000456840_length(amino acids)=372AA_BP=0
MKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSDLTSARNCYQPLLENPMVSES
DFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLKQNPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKG
YSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIF
IFPGLFYLKLSREDFLSWKKLGGLILSHRLACSGVISAHCNLCLPDSSNPPTSASRVAETTEKEEIPWRCAPRGKATQGHSKKATVYKPR

--------------------------------------------------------------
>42158_42158_4_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000354386_SLC38A6_chr14_61512785_ENST00000267488_length(transcript)=1438nt_BP=690nt
AATTTACCTAATCCCACGTCCCTAACGGTCTTCGGAAGCGAAGCAGTGTCAACAGTCCCTGGTAAACACAAGTAGTATTACAAGTCGGGA
GCTCTTCAAGTCTTGGATGAGACTGTAGAGCGGTCTTGTGCGGCAATGTGCTACCTTAAAATAAATAAATAAATAAACCCCTGTTATGTC
CGGAGTTTGTTTCCACCCGGAGAGGAATGGAAGAGCACCAGAGAGCGCTTAGCTTTCTGGTTGGATGTTTTGGTGTGGGACTTGTTTTGT
GACCAACAATATGAAAGGCTCTGAGGTCAGCTTGGAGAAGAAAAAAAAGATTAAGATGCCAGTGAAGAGACTTCGTGAGGTAGTTTCTCA
AAATCATGGAGATCATTTGGTTTTGCTGAAAGATGAGTTGCCCTGTGTTCCTCCGGCATTGTCTGCAAATAAACGTCTTCCTGTTGGAAC
GGGGACTAGTTTGAATGGAACATCACGTGGTTCATCAGACTTAACTTCTGCTAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGT
GTCAGAAAGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGATAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACAT
CTTCATTTCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTTAAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTAC
CAATACAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATT
ACTAAAAGGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCC
TCTAATCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCT
AGCACTCAATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATG
TTTGATTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGATTTTCTGTCATGGAAAAAGCTTGGGGCATTCGTTTTGCT
CATCTTTGGAATTTTGGTTGGGAATTTTAGTTTAGCACTCATCATTTTTGATTGGATTAATAAATAAAAGAAATATTTTCCTACTTCTTA
CAAGAATAATATACCCCTAGTTGCAAGAATGAATTATTCCGGAAGACACCCTGGATGAAAAATAACATTTTAATAAAAATTATTAACAGA

>42158_42158_4_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000354386_SLC38A6_chr14_61512785_ENST00000267488_length(amino acids)=330AA_BP=3
MFWCGTCFVTNNMKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSDLTSARNCY
QPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLKQNPSKKRMQNVTNTAIALSFLIYFISALFGYLT
FYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFG

--------------------------------------------------------------
>42158_42158_5_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000354386_SLC38A6_chr14_61512785_ENST00000354886_length(transcript)=1452nt_BP=690nt
AATTTACCTAATCCCACGTCCCTAACGGTCTTCGGAAGCGAAGCAGTGTCAACAGTCCCTGGTAAACACAAGTAGTATTACAAGTCGGGA
GCTCTTCAAGTCTTGGATGAGACTGTAGAGCGGTCTTGTGCGGCAATGTGCTACCTTAAAATAAATAAATAAATAAACCCCTGTTATGTC
CGGAGTTTGTTTCCACCCGGAGAGGAATGGAAGAGCACCAGAGAGCGCTTAGCTTTCTGGTTGGATGTTTTGGTGTGGGACTTGTTTTGT
GACCAACAATATGAAAGGCTCTGAGGTCAGCTTGGAGAAGAAAAAAAAGATTAAGATGCCAGTGAAGAGACTTCGTGAGGTAGTTTCTCA
AAATCATGGAGATCATTTGGTTTTGCTGAAAGATGAGTTGCCCTGTGTTCCTCCGGCATTGTCTGCAAATAAACGTCTTCCTGTTGGAAC
GGGGACTAGTTTGAATGGAACATCACGTGGTTCATCAGACTTAACTTCTGCTAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGT
GTCAGAAAGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGATAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACAT
CTTCATTTCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTTAAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTAC
CAATACAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATT
ACTAAAAGGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCC
TCTAATCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCT
AGCACTCAATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATG
TTTGATTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGATTTTCTGTCATGGAAAAAGCTTGGGGGTCTCATTCTGTC
GCACAGGTTGGCGTGCAGTGGTGTGATCTCAGCTCATTGCAACCTCTGCCTCCCGGACTCAAGCAATCCTCCCACCTCAGCCTCCAGAGT
AGCTGAGACTACAGGAAGAGATACCATGGAGATGTGCACCCAGAGGAAAGGCCACGCAAGGACACAGCAAGAAGGCAACTGTTTACAAGC
CAAGGGAAGAGGCCTCAGGAGAACCAAACGTGTCCACACCTTGATCTTGCACTTCCCAACCTCCAGAACTGTGAGCAAATAAATGATGTT

>42158_42158_5_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000354386_SLC38A6_chr14_61512785_ENST00000354886_length(amino acids)=395AA_BP=3
MFWCGTCFVTNNMKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSDLTSARNCY
QPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLKQNPSKKRMQNVTNTAIALSFLIYFISALFGYLT
FYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFG
VVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGGLILSHRLACSGVISAHCNLCLPDSSNPPTSASRVAETTGRDTMEMCTQRKGHART

--------------------------------------------------------------
>42158_42158_6_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000354386_SLC38A6_chr14_61512785_ENST00000456840_length(transcript)=1457nt_BP=690nt
AATTTACCTAATCCCACGTCCCTAACGGTCTTCGGAAGCGAAGCAGTGTCAACAGTCCCTGGTAAACACAAGTAGTATTACAAGTCGGGA
GCTCTTCAAGTCTTGGATGAGACTGTAGAGCGGTCTTGTGCGGCAATGTGCTACCTTAAAATAAATAAATAAATAAACCCCTGTTATGTC
CGGAGTTTGTTTCCACCCGGAGAGGAATGGAAGAGCACCAGAGAGCGCTTAGCTTTCTGGTTGGATGTTTTGGTGTGGGACTTGTTTTGT
GACCAACAATATGAAAGGCTCTGAGGTCAGCTTGGAGAAGAAAAAAAAGATTAAGATGCCAGTGAAGAGACTTCGTGAGGTAGTTTCTCA
AAATCATGGAGATCATTTGGTTTTGCTGAAAGATGAGTTGCCCTGTGTTCCTCCGGCATTGTCTGCAAATAAACGTCTTCCTGTTGGAAC
GGGGACTAGTTTGAATGGAACATCACGTGGTTCATCAGACTTAACTTCTGCTAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGT
GTCAGAAAGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGATAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACAT
CTTCATTTCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTTAAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTAC
CAATACAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATT
ACTAAAAGGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCC
TCTAATCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCT
AGCACTCAATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATG
TTTGATTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGATTTTCTGTCATGGAAAAAGCTTGGGGGTCTCATTCTGTC
GCACAGGTTGGCGTGCAGTGGTGTGATCTCAGCTCATTGCAACCTCTGCCTCCCGGACTCAAGCAATCCTCCCACCTCAGCCTCCAGAGT
AGCTGAGACTACAGAAAAGGAAGAGATACCATGGAGATGTGCACCCAGAGGAAAGGCCACGCAAGGACACAGCAAGAAGGCAACTGTTTA
CAAGCCAAGGGAAGAGGCCTCAGGAGAACCAAACGTGTCCACACCTTGATCTTGCACTTCCCAACCTCCAGAACTGTGAGCAAATAAATG

>42158_42158_6_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000354386_SLC38A6_chr14_61512785_ENST00000456840_length(amino acids)=384AA_BP=3
MFWCGTCFVTNNMKGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSDLTSARNCY
QPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLKQNPSKKRMQNVTNTAIALSFLIYFISALFGYLT
FYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFG
VVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGGLILSHRLACSGVISAHCNLCLPDSSNPPTSASRVAETTEKEEIPWRCAPRGKATQ

--------------------------------------------------------------
>42158_42158_7_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000423743_SLC38A6_chr14_61512785_ENST00000267488_length(transcript)=1161nt_BP=413nt
ACAGTCCCTGGTAAACACAAGTAGTATTACAAGTCGGGAGCTCTTCAAGTCTTGGATGAGACTGTAGAGCGGTCTTGTGCGGCAATGTGC
TACCTTAAAATAAATAAATAAATAAACCCCTGTTATGTCCGGAGTTTGTTTCCACCCGGAGAGGAATGGAAGAGCACCAGAGAGCGCTTA
GCTTTCTGGTTGGATGTTTTGGGTTCATCAGACTTAACTTCTGCTAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGTGTCAGAA
AGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGATAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACATCTTCATT
TCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTTAAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTACCAATACA
GCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAAAA
GGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCCTCTAATC
CACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCACTC
AATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATGTTTGATT
TTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGATTTTCTGTCATGGAAAAAGCTTGGGGCATTCGTTTTGCTCATCTTT
GGAATTTTGGTTGGGAATTTTAGTTTAGCACTCATCATTTTTGATTGGATTAATAAATAAAAGAAATATTTTCCTACTTCTTACAAGAAT
AATATACCCCTAGTTGCAAGAATGAATTATTCCGGAAGACACCCTGGATGAAAAATAACATTTTAATAAAAATTATTAACAGAAAAGCAG

>42158_42158_7_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000423743_SLC38A6_chr14_61512785_ENST00000267488_length(amino acids)=274AA_BP=93
MFPPGEEWKSTRERLAFWLDVLGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVL
KQNPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSN
FPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGAFVLLIFGILVGNFSLALIIFD

--------------------------------------------------------------
>42158_42158_8_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000423743_SLC38A6_chr14_61512785_ENST00000354886_length(transcript)=1175nt_BP=413nt
ACAGTCCCTGGTAAACACAAGTAGTATTACAAGTCGGGAGCTCTTCAAGTCTTGGATGAGACTGTAGAGCGGTCTTGTGCGGCAATGTGC
TACCTTAAAATAAATAAATAAATAAACCCCTGTTATGTCCGGAGTTTGTTTCCACCCGGAGAGGAATGGAAGAGCACCAGAGAGCGCTTA
GCTTTCTGGTTGGATGTTTTGGGTTCATCAGACTTAACTTCTGCTAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGTGTCAGAA
AGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGATAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACATCTTCATT
TCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTTAAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTACCAATACA
GCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAAAA
GGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCCTCTAATC
CACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCACTC
AATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATGTTTGATT
TTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGATTTTCTGTCATGGAAAAAGCTTGGGGGTCTCATTCTGTCGCACAGG
TTGGCGTGCAGTGGTGTGATCTCAGCTCATTGCAACCTCTGCCTCCCGGACTCAAGCAATCCTCCCACCTCAGCCTCCAGAGTAGCTGAG
ACTACAGGAAGAGATACCATGGAGATGTGCACCCAGAGGAAAGGCCACGCAAGGACACAGCAAGAAGGCAACTGTTTACAAGCCAAGGGA
AGAGGCCTCAGGAGAACCAAACGTGTCCACACCTTGATCTTGCACTTCCCAACCTCCAGAACTGTGAGCAAATAAATGATGTTGTTTAAT

>42158_42158_8_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000423743_SLC38A6_chr14_61512785_ENST00000354886_length(amino acids)=339AA_BP=93
MFPPGEEWKSTRERLAFWLDVLGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVL
KQNPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSN
FPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGGLILSHRLACSGVISAHCNLCL

--------------------------------------------------------------
>42158_42158_9_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000423743_SLC38A6_chr14_61512785_ENST00000456840_length(transcript)=1180nt_BP=413nt
ACAGTCCCTGGTAAACACAAGTAGTATTACAAGTCGGGAGCTCTTCAAGTCTTGGATGAGACTGTAGAGCGGTCTTGTGCGGCAATGTGC
TACCTTAAAATAAATAAATAAATAAACCCCTGTTATGTCCGGAGTTTGTTTCCACCCGGAGAGGAATGGAAGAGCACCAGAGAGCGCTTA
GCTTTCTGGTTGGATGTTTTGGGTTCATCAGACTTAACTTCTGCTAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGTGTCAGAA
AGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGATAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACATCTTCATT
TCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTTAAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTACCAATACA
GCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTTTGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAAAA
GGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGTGAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCCTCTAATC
CACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAATTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCACTC
AATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAGAAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATGTTTGATT
TTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGATTTTCTGTCATGGAAAAAGCTTGGGGGTCTCATTCTGTCGCACAGG
TTGGCGTGCAGTGGTGTGATCTCAGCTCATTGCAACCTCTGCCTCCCGGACTCAAGCAATCCTCCCACCTCAGCCTCCAGAGTAGCTGAG
ACTACAGAAAAGGAAGAGATACCATGGAGATGTGCACCCAGAGGAAAGGCCACGCAAGGACACAGCAAGAAGGCAACTGTTTACAAGCCA
AGGGAAGAGGCCTCAGGAGAACCAAACGTGTCCACACCTTGATCTTGCACTTCCCAACCTCCAGAACTGTGAGCAAATAAATGATGTTGT

>42158_42158_9_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000423743_SLC38A6_chr14_61512785_ENST00000456840_length(amino acids)=328AA_BP=93
MFPPGEEWKSTRERLAFWLDVLGSSDLTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVL
KQNPSKKRMQNVTNTAIALSFLIYFISALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSN
FPFSWIRHFLITLALNIIIVLLAIYVPDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGGLILSHRLACSGVISAHCNLCL

--------------------------------------------------------------
>42158_42158_10_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000556134_SLC38A6_chr14_61512785_ENST00000267488_length(transcript)=1387nt_BP=639nt
GTCCCTAACGGTCTTCGGAAGCGAAGCAGTGTCAACAGTCCCTGGTAAACACAAGTAGTATTACAAGTCGGGAGCTCTTCAAGTCTTGGA
TGAGACTGTAGAGCGGTCTTGTGCGGCAATGTGCTACCTTAAAATAAATAAATAAATAAACCCCTGTTATGTCCGGAGTTTGTTTCCACC
CGGAGAGGAATGGAAGAGCACCAGAGAGCGCTTAGCTTTCTGGTTGGATGTTTTGGGCTCTGAGGTCAGCTTGGAGAAGAAAAAAAAGAT
TAAGATGCCAGTGAAGAGACTTCGTGAGGTAGTTTCTCAAAATCATGGAGATCATTTGGTTTTGCTGAAAGATGAGTTGCCCTGTGTTCC
TCCGGCATTGTCTGCAAATAAACGTCTTCCTGTTGGAACGGGGACTAGTTTGAATGGAACATCACGTGGTTCATCAGACTTAACTTCTGC
TAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGTGTCAGAAAGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGA
TAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACATCTTCATTTCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTT
AAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTACCAATACAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTT
TGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAAAAGGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGT
GAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCCTCTAATCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAA
TTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCACTCAATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAG
AAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATGTTTGATTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGA
TTTTCTGTCATGGAAAAAGCTTGGGGCATTCGTTTTGCTCATCTTTGGAATTTTGGTTGGGAATTTTAGTTTAGCACTCATCATTTTTGA
TTGGATTAATAAATAAAAGAAATATTTTCCTACTTCTTACAAGAATAATATACCCCTAGTTGCAAGAATGAATTATTCCGGAAGACACCC
TGGATGAAAAATAACATTTTAATAAAAATTATTAACAGAAAAGCAGAACAAAATGGCAGTGGGTATGGGGAAGTAAGAGTGTGGCAGTTT

>42158_42158_10_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000556134_SLC38A6_chr14_61512785_ENST00000267488_length(amino acids)=338AA_BP=1
MFPPGEEWKSTRERLAFWLDVLGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSD
LTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLKQNPSKKRMQNVTNTAIALSFLIYFI
SALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYV

--------------------------------------------------------------
>42158_42158_11_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000556134_SLC38A6_chr14_61512785_ENST00000354886_length(transcript)=1401nt_BP=639nt
GTCCCTAACGGTCTTCGGAAGCGAAGCAGTGTCAACAGTCCCTGGTAAACACAAGTAGTATTACAAGTCGGGAGCTCTTCAAGTCTTGGA
TGAGACTGTAGAGCGGTCTTGTGCGGCAATGTGCTACCTTAAAATAAATAAATAAATAAACCCCTGTTATGTCCGGAGTTTGTTTCCACC
CGGAGAGGAATGGAAGAGCACCAGAGAGCGCTTAGCTTTCTGGTTGGATGTTTTGGGCTCTGAGGTCAGCTTGGAGAAGAAAAAAAAGAT
TAAGATGCCAGTGAAGAGACTTCGTGAGGTAGTTTCTCAAAATCATGGAGATCATTTGGTTTTGCTGAAAGATGAGTTGCCCTGTGTTCC
TCCGGCATTGTCTGCAAATAAACGTCTTCCTGTTGGAACGGGGACTAGTTTGAATGGAACATCACGTGGTTCATCAGACTTAACTTCTGC
TAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGTGTCAGAAAGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGA
TAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACATCTTCATTTCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTT
AAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTACCAATACAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTT
TGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAAAAGGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGT
GAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCCTCTAATCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAA
TTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCACTCAATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAG
AAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATGTTTGATTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGA
TTTTCTGTCATGGAAAAAGCTTGGGGGTCTCATTCTGTCGCACAGGTTGGCGTGCAGTGGTGTGATCTCAGCTCATTGCAACCTCTGCCT
CCCGGACTCAAGCAATCCTCCCACCTCAGCCTCCAGAGTAGCTGAGACTACAGGAAGAGATACCATGGAGATGTGCACCCAGAGGAAAGG
CCACGCAAGGACACAGCAAGAAGGCAACTGTTTACAAGCCAAGGGAAGAGGCCTCAGGAGAACCAAACGTGTCCACACCTTGATCTTGCA

>42158_42158_11_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000556134_SLC38A6_chr14_61512785_ENST00000354886_length(amino acids)=403AA_BP=1
MFPPGEEWKSTRERLAFWLDVLGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSD
LTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLKQNPSKKRMQNVTNTAIALSFLIYFI
SALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYV
PDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGGLILSHRLACSGVISAHCNLCLPDSSNPPTSASRVAETTGRDTMEMCT

--------------------------------------------------------------
>42158_42158_12_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000556134_SLC38A6_chr14_61512785_ENST00000456840_length(transcript)=1406nt_BP=639nt
GTCCCTAACGGTCTTCGGAAGCGAAGCAGTGTCAACAGTCCCTGGTAAACACAAGTAGTATTACAAGTCGGGAGCTCTTCAAGTCTTGGA
TGAGACTGTAGAGCGGTCTTGTGCGGCAATGTGCTACCTTAAAATAAATAAATAAATAAACCCCTGTTATGTCCGGAGTTTGTTTCCACC
CGGAGAGGAATGGAAGAGCACCAGAGAGCGCTTAGCTTTCTGGTTGGATGTTTTGGGCTCTGAGGTCAGCTTGGAGAAGAAAAAAAAGAT
TAAGATGCCAGTGAAGAGACTTCGTGAGGTAGTTTCTCAAAATCATGGAGATCATTTGGTTTTGCTGAAAGATGAGTTGCCCTGTGTTCC
TCCGGCATTGTCTGCAAATAAACGTCTTCCTGTTGGAACGGGGACTAGTTTGAATGGAACATCACGTGGTTCATCAGACTTAACTTCTGC
TAGAAATTGTTACCAGCCTCTATTAGAAAATCCCATGGTGTCAGAAAGTGATTTTTCTAAAGACGTTGCAGTGCAAGTGTTGCCTTTGGA
TAAAATAGAAGAGAACAACAAGCAAAAAGCAAATGACATCTTCATTTCTCAGTATACAATGGGACAGAAAGATGCTCTAAGAACAGTTTT
AAAGCAAAATCCTTCAAAGAAAAGAATGCAGAATGTTACCAATACAGCAATTGCTTTAAGTTTTCTCATTTATTTTATATCTGCACTCTT
TGGGTACCTCACTTTTTATGACAAAGTGGAGTCAGAATTACTAAAAGGTTATAGTAAATACTTATCACATGATGTTGTTGTCATGACTGT
GAAGTTATGCATACTATTTGCTGTGCTTTTGACAGTCCCTCTAATCCACTTCCCTGCCAGAAAAGCTGTAACAATGATGTTTTTCTCCAA
TTTTCCATTCTCATGGATTCGCCATTTTTTGATCACTCTAGCACTCAATATTATCATCGTTTTACTTGCAATATATGTTCCTGACATTAG
AAATGTATTTGGTGTAGTTGGTGCCAGTACATCAACATGTTTGATTTTTATATTCCCAGGACTATTTTATCTTAAACTTAGCAGAGAGGA
TTTTCTGTCATGGAAAAAGCTTGGGGGTCTCATTCTGTCGCACAGGTTGGCGTGCAGTGGTGTGATCTCAGCTCATTGCAACCTCTGCCT
CCCGGACTCAAGCAATCCTCCCACCTCAGCCTCCAGAGTAGCTGAGACTACAGAAAAGGAAGAGATACCATGGAGATGTGCACCCAGAGG
AAAGGCCACGCAAGGACACAGCAAGAAGGCAACTGTTTACAAGCCAAGGGAAGAGGCCTCAGGAGAACCAAACGTGTCCACACCTTGATC

>42158_42158_12_KIAA0586-SLC38A6_KIAA0586_chr14_58899175_ENST00000556134_SLC38A6_chr14_61512785_ENST00000456840_length(amino acids)=392AA_BP=1
MFPPGEEWKSTRERLAFWLDVLGSEVSLEKKKKIKMPVKRLREVVSQNHGDHLVLLKDELPCVPPALSANKRLPVGTGTSLNGTSRGSSD
LTSARNCYQPLLENPMVSESDFSKDVAVQVLPLDKIEENNKQKANDIFISQYTMGQKDALRTVLKQNPSKKRMQNVTNTAIALSFLIYFI
SALFGYLTFYDKVESELLKGYSKYLSHDVVVMTVKLCILFAVLLTVPLIHFPARKAVTMMFFSNFPFSWIRHFLITLALNIIIVLLAIYV
PDIRNVFGVVGASTSTCLIFIFPGLFYLKLSREDFLSWKKLGGLILSHRLACSGVISAHCNLCLPDSSNPPTSASRVAETTEKEEIPWRC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for KIAA0586-SLC38A6


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KIAA0586-SLC38A6


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KIAA0586-SLC38A6


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource