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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KIAA0907-UBQLN4 (FusionGDB2 ID:42199)

Fusion Gene Summary for KIAA0907-UBQLN4

check button Fusion gene summary
Fusion gene informationFusion gene name: KIAA0907-UBQLN4
Fusion gene ID: 42199
HgeneTgene
Gene symbol

KIAA0907

UBQLN4

Gene ID

22889

56893

Gene nameKH domain containing 4, pre-mRNA splicing factorubiquilin 4
SynonymsBLOM7|KIAA0907|SNORA80EHGA1U|A1Up|C1orf6|CIP75|UBIN
Cytomap

1q22

1q22

Type of geneprotein-codingprotein-coding
DescriptionKH homology domain-containing protein 4brings lots of money 7pre-mRNA splicing factor protein KHDC4protein BLOM7ubiquilin-4ataxin-1 interacting ubiquitin-like proteinataxin-1 ubiquitin-like interacting proteinataxin-1 ubiquitin-like-interacting protein A1Uconnexin43-interacting protein of 75 kDa
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000368319, ENST00000368320, 
ENST00000368321, ENST00000482337, 
ENST00000472638, ENST00000368309, 
Fusion gene scores* DoF score10 X 11 X 9=9906 X 6 X 7=252
# samples 138
** MAII scorelog2(13/990*10)=-2.92891690193852
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/252*10)=-1.65535182861255
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KIAA0907 [Title/Abstract] AND UBQLN4 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKIAA0907(155896466)-UBQLN4(156014014), # samples:1
KIAA0907(155903616)-UBQLN4(156023500), # samples:1
KIAA0907(155896467)-UBQLN4(156014014), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKIAA0907

GO:0006376

mRNA splice site selection

19641227

TgeneUBQLN4

GO:0006974

cellular response to DNA damage stimulus

30612738

TgeneUBQLN4

GO:0032434

regulation of proteasomal ubiquitin-dependent protein catabolic process

27113755

TgeneUBQLN4

GO:2000042

negative regulation of double-strand break repair via homologous recombination

30612738


check buttonFusion gene breakpoints across KIAA0907 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across UBQLN4 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUSCTCGA-77-7142KIAA0907chr1

155903616

-UBQLN4chr1

156023500

-
ChimerDB4STADTCGA-BR-A452-01AKIAA0907chr1

155896467

-UBQLN4chr1

156014014

-
ChimerDB4STADTCGA-BR-A452KIAA0907chr1

155896466

-UBQLN4chr1

156014014

-


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Fusion Gene ORF analysis for KIAA0907-UBQLN4

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000368319ENST00000472638KIAA0907chr1

155896467

-UBQLN4chr1

156014014

-
5CDS-intronENST00000368319ENST00000472638KIAA0907chr1

155896466

-UBQLN4chr1

156014014

-
5CDS-intronENST00000368320ENST00000472638KIAA0907chr1

155896467

-UBQLN4chr1

156014014

-
5CDS-intronENST00000368320ENST00000472638KIAA0907chr1

155896466

-UBQLN4chr1

156014014

-
5CDS-intronENST00000368321ENST00000472638KIAA0907chr1

155896467

-UBQLN4chr1

156014014

-
5CDS-intronENST00000368321ENST00000472638KIAA0907chr1

155896466

-UBQLN4chr1

156014014

-
5UTR-3CDSENST00000482337ENST00000368309KIAA0907chr1

155896467

-UBQLN4chr1

156014014

-
5UTR-3CDSENST00000482337ENST00000368309KIAA0907chr1

155896466

-UBQLN4chr1

156014014

-
5UTR-intronENST00000482337ENST00000472638KIAA0907chr1

155896467

-UBQLN4chr1

156014014

-
5UTR-intronENST00000482337ENST00000472638KIAA0907chr1

155896466

-UBQLN4chr1

156014014

-
In-frameENST00000368319ENST00000368309KIAA0907chr1

155896467

-UBQLN4chr1

156014014

-
In-frameENST00000368319ENST00000368309KIAA0907chr1

155896466

-UBQLN4chr1

156014014

-
In-frameENST00000368320ENST00000368309KIAA0907chr1

155896467

-UBQLN4chr1

156014014

-
In-frameENST00000368320ENST00000368309KIAA0907chr1

155896466

-UBQLN4chr1

156014014

-
In-frameENST00000368321ENST00000368309KIAA0907chr1

155896467

-UBQLN4chr1

156014014

-
In-frameENST00000368321ENST00000368309KIAA0907chr1

155896466

-UBQLN4chr1

156014014

-
intron-5UTRENST00000368319ENST00000368309KIAA0907chr1

155903616

-UBQLN4chr1

156023500

-
intron-5UTRENST00000368320ENST00000368309KIAA0907chr1

155903616

-UBQLN4chr1

156023500

-
intron-5UTRENST00000368321ENST00000368309KIAA0907chr1

155903616

-UBQLN4chr1

156023500

-
intron-5UTRENST00000482337ENST00000368309KIAA0907chr1

155903616

-UBQLN4chr1

156023500

-
intron-intronENST00000368319ENST00000472638KIAA0907chr1

155903616

-UBQLN4chr1

156023500

-
intron-intronENST00000368320ENST00000472638KIAA0907chr1

155903616

-UBQLN4chr1

156023500

-
intron-intronENST00000368321ENST00000472638KIAA0907chr1

155903616

-UBQLN4chr1

156023500

-
intron-intronENST00000482337ENST00000472638KIAA0907chr1

155903616

-UBQLN4chr1

156023500

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000368321KIAA0907chr1155896466-ENST00000368309UBQLN4chr1156014014-3288705241610528
ENST00000368320KIAA0907chr1155896466-ENST00000368309UBQLN4chr1156014014-3290707261612528
ENST00000368319KIAA0907chr1155896466-ENST00000368309UBQLN4chr1156014014-326468101586528
ENST00000368321KIAA0907chr1155896467-ENST00000368309UBQLN4chr1156014014-3288705241610528
ENST00000368320KIAA0907chr1155896467-ENST00000368309UBQLN4chr1156014014-3290707261612528
ENST00000368319KIAA0907chr1155896467-ENST00000368309UBQLN4chr1156014014-326468101586528

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000368321ENST00000368309KIAA0907chr1155896466-UBQLN4chr1156014014-0.0103716690.9896283
ENST00000368320ENST00000368309KIAA0907chr1155896466-UBQLN4chr1156014014-0.0103666590.9896333
ENST00000368319ENST00000368309KIAA0907chr1155896466-UBQLN4chr1156014014-0.0103103490.9896897
ENST00000368321ENST00000368309KIAA0907chr1155896467-UBQLN4chr1156014014-0.0103716690.9896283
ENST00000368320ENST00000368309KIAA0907chr1155896467-UBQLN4chr1156014014-0.0103666590.9896333
ENST00000368319ENST00000368309KIAA0907chr1155896467-UBQLN4chr1156014014-0.0103103490.9896897

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Fusion Genomic Features for KIAA0907-UBQLN4


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KIAA0907-UBQLN4


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:155896466/chr1:156014014)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368319-610100_180227385.0DomainKH 1
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368320-613100_180227565.0DomainKH 1
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368321-614100_180227615.0DomainKH 1
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368319-610100_180227385.0DomainKH 1
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368320-613100_180227565.0DomainKH 1
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368321-614100_180227615.0DomainKH 1
TgeneUBQLN4chr1:155896466chr1:156014014ENST00000368309411393_440300602.0DomainSTI1 3
TgeneUBQLN4chr1:155896466chr1:156014014ENST00000368309411444_476300602.0DomainSTI1 4
TgeneUBQLN4chr1:155896466chr1:156014014ENST00000368309411553_598300602.0DomainUBA
TgeneUBQLN4chr1:155896467chr1:156014014ENST00000368309411393_440300602.0DomainSTI1 3
TgeneUBQLN4chr1:155896467chr1:156014014ENST00000368309411444_476300602.0DomainSTI1 4
TgeneUBQLN4chr1:155896467chr1:156014014ENST00000368309411553_598300602.0DomainUBA

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368319-610335_457227385.0Compositional biasNote=Pro-rich
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368320-613335_457227565.0Compositional biasNote=Pro-rich
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368321-614335_457227615.0Compositional biasNote=Pro-rich
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368319-610335_457227385.0Compositional biasNote=Pro-rich
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368320-613335_457227565.0Compositional biasNote=Pro-rich
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368321-614335_457227615.0Compositional biasNote=Pro-rich
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368319-610235_317227385.0DomainKH 2
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368320-613235_317227565.0DomainKH 2
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368321-614235_317227615.0DomainKH 2
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368319-610235_317227385.0DomainKH 2
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368320-613235_317227565.0DomainKH 2
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368321-614235_317227615.0DomainKH 2
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368319-610480_549227385.0RegionRequired for nuclear retention
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368320-613480_549227565.0RegionRequired for nuclear retention
HgeneKIAA0907chr1:155896466chr1:156014014ENST00000368321-614480_549227615.0RegionRequired for nuclear retention
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368319-610480_549227385.0RegionRequired for nuclear retention
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368320-613480_549227565.0RegionRequired for nuclear retention
HgeneKIAA0907chr1:155896467chr1:156014014ENST00000368321-614480_549227615.0RegionRequired for nuclear retention
TgeneUBQLN4chr1:155896466chr1:156014014ENST0000036830941113_87300602.0DomainUbiquitin-like
TgeneUBQLN4chr1:155896466chr1:156014014ENST00000368309411192_229300602.0DomainSTI1 1
TgeneUBQLN4chr1:155896466chr1:156014014ENST00000368309411230_261300602.0DomainSTI1 2
TgeneUBQLN4chr1:155896467chr1:156014014ENST0000036830941113_87300602.0DomainUbiquitin-like
TgeneUBQLN4chr1:155896467chr1:156014014ENST00000368309411192_229300602.0DomainSTI1 1
TgeneUBQLN4chr1:155896467chr1:156014014ENST00000368309411230_261300602.0DomainSTI1 2


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Fusion Gene Sequence for KIAA0907-UBQLN4


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42199_42199_1_KIAA0907-UBQLN4_KIAA0907_chr1_155896466_ENST00000368319_UBQLN4_chr1_156014014_ENST00000368309_length(transcript)=3264nt_BP=681nt
ATGTCCGCGGGGAGCGCGACACATCCTGGAGCTGGCGGGCGCCGCAGCAAATGGGACCAACCAGCTCCAGCCCCACTTCTCTTCCTCCCG
CCAGCGGCCCCAGGTGGGGAGGTCACCAGCAGTGGGGGAAGTCCTGGGGGCACCACAGCTGCTCCTTCAGGAGCCTTGGATGCTGCTGCT
GCTGTGGCTGCCAAGATTAATGCCATGCTCATGGCAAAAGGGAAGCTGAAACCAACTCAGAATGCTTCTGAGAAGCTTCAGGCTCCTGGC
AAAGGCCTAACTAGCAATAAAAGCAAGGATGACCTGGTGGTAGCTGAAGTAGAAATTAATGATGTGCCTCTCACATGTAGGAACTTGCTG
ACTCGAGGACAGACTCAAGACGAGATCAGCCGACTTAGTGGGGCTGCAGTATCAACTCGAGGGAGGTTCATGACAACTGAGGAAAAAGCC
AAAGTGGGACCAGGGGATCGTCCATTATATCTTCATGTTCAGGGCCAGACACGGGAATTAGTGGACAGAGCTGTAAACCGGATCAAAGAA
ATTATCACCAATGGAGTGGTAAAAGCTGCCACAGGAACAAGTCCAACTTTTAATGGTGCAACAGTAACTGTCTATCACCAGCCAGCACCC
ATCGCTCAGTTGTCTCCAGCTGTTAGCCAGAAGCCTCCCTTCCAGTCAGGGTTTGGCAACAATCCCTTCTCTTCCCTGGCCGGGAACTCC
GACAGCTCATCCTCCCAGCCTCTGCGGACTGAGAATCGAGAGCCCCTCCCTAACCCCTGGAGCCCCTCGCCCCCCACCTCCCAGGCCCCC
GGGTCCGGTGGGGAGGGCACCGGAGGATCGGGGACCAGCCAGGTGCACCCGACAGTCTCGAACCCCTTTGGGATCAATGCGGCTAGCCTG
GGGTCAGGGATGTTCAATAGCCCAGAAATGCAAGCCCTCCTCCAGCAGATCTCTGAGAACCCCCAGCTGATGCAGAATGTGATCTCAGCA
CCCTACATGCGCAGCATGATGCAGACGCTTGCCCAGAACCCCGACTTTGCTGCTCAGATGATGGTGAATGTGCCGCTCTTCGCGGGGAAC
CCCCAACTGCAGGAGCAGCTCCGCCTGCAGCTCCCAGTCTTCCTGCAGCAGATGCAGAACCCAGAGTCACTCTCCATCCTTACCAATCCC
CGAGCCATGCAGGCATTGCTGCAGATCCAGCAGGGACTACAGACCTTGCAGACCGAGGCCCCTGGGCTGGTACCCAGCCTTGGCTCCTTT
GGGATATCCCGGACCCCAGCACCCTCAGCAGGCAGCAACGCAGGGTCTACGCCCGAGGCCCCCACTTCCTCACCAGCCACGCCAGCCACA
TCTTCTCCAACAGGGGCTTCCAGCGCCCAGCAGCAACTCATGCAGCAGATGATCCAGCTTTTGGCTGGAAGTGGAAACTCACAGGTGCAG
ACGCCAGAAGTGAGATTTCAGCAGCAGCTGGAGCAGCTCAACTCCATGGGCTTCATCAATCGTGAGGCTAACCTGCAGGCCCTGATTGCC
ACAGGAGGGGACATCAACGCAGCTATCGAGAGACTGCTGGGCTCCCAGCTCTCCTAATCCCTCGGCCCATGCCTCCTGCCTCTCCCCTCC
CTCGATGTCAGCATTCGGTTCTTCTGTCAATCCTTACCCTCTGCAGCTTGTCCTCCCTTCCGTCTTCTCCCTCATCCTTTCCAAACAGCA
GGGTGACTTTAGAGGCATGGGCTCCAACCCCTTAGCTCTGTCTGAGAATTATGGTTTTACTGCTACGTCTCTAACAGACTCTTCTCTCCT
GGTCTCCTTGAGCAGTGCTACTTAAACAGTTTTCACAGTTTCATTGATTGACTCTACCTCCTTGCCCCACACCACTTTTGCAATCTTTAA
ACTTTCAGTGGCTGTGCAGAGTCGAGGGAGGAACCAGCTCTCTGGTTTACTGGAACATAGTCTTCCATCTATACCACTAGGGTTTTGTCT
TATGTTTACTTTTGGTAACTCTCTTCCTTCTTTTTCTCCCTACCCCCCAACCCCTAGCCCAACCAATGCTAGAATTTCTTGCTCTGAAGG
AGGAGCAGGTGAAACAGGTGGTAATTTTCCTTCTCGGCCCCTATTCTGGTTCATTCAGCACTTTTTGGTGGGAACTGTTGGAAATTCCAG
GGTAAGGAGGAAGATGCCTGTTCTCCCTGTCTGAAGAGGGAGATGAGACAGCTCTCTGGACAGGAATTAACAAACGCTGGAGCAGCCCAG
AGGAAATTCGTGTGAAAGAGGAGGGAATGAGATTATTCGGAGGAAGGGAATGGGGGAGACAGCCTGAGTAAAAGGCTTGGAAGTTGGAAT
TAACAGTGGGGAGCAGAAGCACTCATAGCTCTTTTAGGCAGAAGAATCCAGGCCCGAGCTGGCAGAAGAGACTTAGAGATGCTAATGGAA
TTTAAACTGAAAAAAGGAGCCCAATGAAGCTAAGCGCCACGCCCCACAAGGGGTCATATTGGCTTTAGTTCCTCAAGCATATGTGCTTAT
ATGCACACACACACACATTTCCATGGACCCAGGTCTTGCTTGTGTCCCCAGGCACCAGTAGTTTGAGCCCCCCTCAAAAGACATGAAGGG
GGTTGGGGTCTGTGTGAGTAGTGGGGAGGTGCATGTGTATCCACATGTGTGCATACACTCTTAAGTTGGGTGGGAAGTGGATTCCTTGTT
GGTTTCTGGTTCAGAGTGCTCTCCCACCACCAGAGACAAGTGGGTAAAAAGGTCAGTCCATTGCAGGAATATATATCCGGGAGAGCTAGG
TCCCTTGGGGCTCTGGATGCTGGGTAACCCAGAGGTAATGTGGGTACCCTTTCTGAAGCTGTCAGGGCTGTGACTAGCACCCTTATCACC
CCTCACTGCCTTGTGGGAATAGTAGAGGGTTTTTTTCCTCCAGAGCCCCTGGCCTTTCAGTTCTTAACTATTTCCCTCCAGGCCAGAAAG
TTTTCTTTGAGGAAGGAGAGGAGAGGGTGGCAATGATGCCTTTGATCTGGAATTGGACATTTCTCTGTCAGAGCACAGAGGAGGCTCATA
TCACCTCTTCCCTCTCCTACTTGGCCCAGCTGCTTGGAGGACCGACCCCATGGCTGAGAATATGACGGCAAGAGGAACAGAGTTTGCTCC
AAGTGGGAAAGGGTCCCAAGCAGTCCAGAGAAGATGTCTGTGTGGCTTTCCCTCCCTGCCTCCCCCAGCTCCCACACTGGCCTTTGTAAA

>42199_42199_1_KIAA0907-UBQLN4_KIAA0907_chr1_155896466_ENST00000368319_UBQLN4_chr1_156014014_ENST00000368309_length(amino acids)=528AA_BP=225
MSAGSATHPGAGGRRSKWDQPAPAPLLFLPPAAPGGEVTSSGGSPGGTTAAPSGALDAAAAVAAKINAMLMAKGKLKPTQNASEKLQAPG
KGLTSNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTTEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKE
IITNGVVKAATGTSPTFNGATVTVYHQPAPIAQLSPAVSQKPPFQSGFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAP
GSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGN
PQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPAT

--------------------------------------------------------------
>42199_42199_2_KIAA0907-UBQLN4_KIAA0907_chr1_155896466_ENST00000368320_UBQLN4_chr1_156014014_ENST00000368309_length(transcript)=3290nt_BP=707nt
CGGGTGGTTGAGTAGAAGCGGTCGCCATGTCCGCGGGGAGCGCGACACATCCTGGAGCTGGCGGGCGCCGCAGCAAATGGGACCAACCAG
CTCCAGCCCCACTTCTCTTCCTCCCGCCAGCGGCCCCAGGTGGGGAGGTCACCAGCAGTGGGGGAAGTCCTGGGGGCACCACAGCTGCTC
CTTCAGGAGCCTTGGATGCTGCTGCTGCTGTGGCTGCCAAGATTAATGCCATGCTCATGGCAAAAGGGAAGCTGAAACCAACTCAGAATG
CTTCTGAGAAGCTTCAGGCTCCTGGCAAAGGCCTAACTAGCAATAAAAGCAAGGATGACCTGGTGGTAGCTGAAGTAGAAATTAATGATG
TGCCTCTCACATGTAGGAACTTGCTGACTCGAGGACAGACTCAAGACGAGATCAGCCGACTTAGTGGGGCTGCAGTATCAACTCGAGGGA
GGTTCATGACAACTGAGGAAAAAGCCAAAGTGGGACCAGGGGATCGTCCATTATATCTTCATGTTCAGGGCCAGACACGGGAATTAGTGG
ACAGAGCTGTAAACCGGATCAAAGAAATTATCACCAATGGAGTGGTAAAAGCTGCCACAGGAACAAGTCCAACTTTTAATGGTGCAACAG
TAACTGTCTATCACCAGCCAGCACCCATCGCTCAGTTGTCTCCAGCTGTTAGCCAGAAGCCTCCCTTCCAGTCAGGGTTTGGCAACAATC
CCTTCTCTTCCCTGGCCGGGAACTCCGACAGCTCATCCTCCCAGCCTCTGCGGACTGAGAATCGAGAGCCCCTCCCTAACCCCTGGAGCC
CCTCGCCCCCCACCTCCCAGGCCCCCGGGTCCGGTGGGGAGGGCACCGGAGGATCGGGGACCAGCCAGGTGCACCCGACAGTCTCGAACC
CCTTTGGGATCAATGCGGCTAGCCTGGGGTCAGGGATGTTCAATAGCCCAGAAATGCAAGCCCTCCTCCAGCAGATCTCTGAGAACCCCC
AGCTGATGCAGAATGTGATCTCAGCACCCTACATGCGCAGCATGATGCAGACGCTTGCCCAGAACCCCGACTTTGCTGCTCAGATGATGG
TGAATGTGCCGCTCTTCGCGGGGAACCCCCAACTGCAGGAGCAGCTCCGCCTGCAGCTCCCAGTCTTCCTGCAGCAGATGCAGAACCCAG
AGTCACTCTCCATCCTTACCAATCCCCGAGCCATGCAGGCATTGCTGCAGATCCAGCAGGGACTACAGACCTTGCAGACCGAGGCCCCTG
GGCTGGTACCCAGCCTTGGCTCCTTTGGGATATCCCGGACCCCAGCACCCTCAGCAGGCAGCAACGCAGGGTCTACGCCCGAGGCCCCCA
CTTCCTCACCAGCCACGCCAGCCACATCTTCTCCAACAGGGGCTTCCAGCGCCCAGCAGCAACTCATGCAGCAGATGATCCAGCTTTTGG
CTGGAAGTGGAAACTCACAGGTGCAGACGCCAGAAGTGAGATTTCAGCAGCAGCTGGAGCAGCTCAACTCCATGGGCTTCATCAATCGTG
AGGCTAACCTGCAGGCCCTGATTGCCACAGGAGGGGACATCAACGCAGCTATCGAGAGACTGCTGGGCTCCCAGCTCTCCTAATCCCTCG
GCCCATGCCTCCTGCCTCTCCCCTCCCTCGATGTCAGCATTCGGTTCTTCTGTCAATCCTTACCCTCTGCAGCTTGTCCTCCCTTCCGTC
TTCTCCCTCATCCTTTCCAAACAGCAGGGTGACTTTAGAGGCATGGGCTCCAACCCCTTAGCTCTGTCTGAGAATTATGGTTTTACTGCT
ACGTCTCTAACAGACTCTTCTCTCCTGGTCTCCTTGAGCAGTGCTACTTAAACAGTTTTCACAGTTTCATTGATTGACTCTACCTCCTTG
CCCCACACCACTTTTGCAATCTTTAAACTTTCAGTGGCTGTGCAGAGTCGAGGGAGGAACCAGCTCTCTGGTTTACTGGAACATAGTCTT
CCATCTATACCACTAGGGTTTTGTCTTATGTTTACTTTTGGTAACTCTCTTCCTTCTTTTTCTCCCTACCCCCCAACCCCTAGCCCAACC
AATGCTAGAATTTCTTGCTCTGAAGGAGGAGCAGGTGAAACAGGTGGTAATTTTCCTTCTCGGCCCCTATTCTGGTTCATTCAGCACTTT
TTGGTGGGAACTGTTGGAAATTCCAGGGTAAGGAGGAAGATGCCTGTTCTCCCTGTCTGAAGAGGGAGATGAGACAGCTCTCTGGACAGG
AATTAACAAACGCTGGAGCAGCCCAGAGGAAATTCGTGTGAAAGAGGAGGGAATGAGATTATTCGGAGGAAGGGAATGGGGGAGACAGCC
TGAGTAAAAGGCTTGGAAGTTGGAATTAACAGTGGGGAGCAGAAGCACTCATAGCTCTTTTAGGCAGAAGAATCCAGGCCCGAGCTGGCA
GAAGAGACTTAGAGATGCTAATGGAATTTAAACTGAAAAAAGGAGCCCAATGAAGCTAAGCGCCACGCCCCACAAGGGGTCATATTGGCT
TTAGTTCCTCAAGCATATGTGCTTATATGCACACACACACACATTTCCATGGACCCAGGTCTTGCTTGTGTCCCCAGGCACCAGTAGTTT
GAGCCCCCCTCAAAAGACATGAAGGGGGTTGGGGTCTGTGTGAGTAGTGGGGAGGTGCATGTGTATCCACATGTGTGCATACACTCTTAA
GTTGGGTGGGAAGTGGATTCCTTGTTGGTTTCTGGTTCAGAGTGCTCTCCCACCACCAGAGACAAGTGGGTAAAAAGGTCAGTCCATTGC
AGGAATATATATCCGGGAGAGCTAGGTCCCTTGGGGCTCTGGATGCTGGGTAACCCAGAGGTAATGTGGGTACCCTTTCTGAAGCTGTCA
GGGCTGTGACTAGCACCCTTATCACCCCTCACTGCCTTGTGGGAATAGTAGAGGGTTTTTTTCCTCCAGAGCCCCTGGCCTTTCAGTTCT
TAACTATTTCCCTCCAGGCCAGAAAGTTTTCTTTGAGGAAGGAGAGGAGAGGGTGGCAATGATGCCTTTGATCTGGAATTGGACATTTCT
CTGTCAGAGCACAGAGGAGGCTCATATCACCTCTTCCCTCTCCTACTTGGCCCAGCTGCTTGGAGGACCGACCCCATGGCTGAGAATATG
ACGGCAAGAGGAACAGAGTTTGCTCCAAGTGGGAAAGGGTCCCAAGCAGTCCAGAGAAGATGTCTGTGTGGCTTTCCCTCCCTGCCTCCC

>42199_42199_2_KIAA0907-UBQLN4_KIAA0907_chr1_155896466_ENST00000368320_UBQLN4_chr1_156014014_ENST00000368309_length(amino acids)=528AA_BP=225
MSAGSATHPGAGGRRSKWDQPAPAPLLFLPPAAPGGEVTSSGGSPGGTTAAPSGALDAAAAVAAKINAMLMAKGKLKPTQNASEKLQAPG
KGLTSNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTTEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKE
IITNGVVKAATGTSPTFNGATVTVYHQPAPIAQLSPAVSQKPPFQSGFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAP
GSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGN
PQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPAT

--------------------------------------------------------------
>42199_42199_3_KIAA0907-UBQLN4_KIAA0907_chr1_155896466_ENST00000368321_UBQLN4_chr1_156014014_ENST00000368309_length(transcript)=3288nt_BP=705nt
GGTGGTTGAGTAGAAGCGGTCGCCATGTCCGCGGGGAGCGCGACACATCCTGGAGCTGGCGGGCGCCGCAGCAAATGGGACCAACCAGCT
CCAGCCCCACTTCTCTTCCTCCCGCCAGCGGCCCCAGGTGGGGAGGTCACCAGCAGTGGGGGAAGTCCTGGGGGCACCACAGCTGCTCCT
TCAGGAGCCTTGGATGCTGCTGCTGCTGTGGCTGCCAAGATTAATGCCATGCTCATGGCAAAAGGGAAGCTGAAACCAACTCAGAATGCT
TCTGAGAAGCTTCAGGCTCCTGGCAAAGGCCTAACTAGCAATAAAAGCAAGGATGACCTGGTGGTAGCTGAAGTAGAAATTAATGATGTG
CCTCTCACATGTAGGAACTTGCTGACTCGAGGACAGACTCAAGACGAGATCAGCCGACTTAGTGGGGCTGCAGTATCAACTCGAGGGAGG
TTCATGACAACTGAGGAAAAAGCCAAAGTGGGACCAGGGGATCGTCCATTATATCTTCATGTTCAGGGCCAGACACGGGAATTAGTGGAC
AGAGCTGTAAACCGGATCAAAGAAATTATCACCAATGGAGTGGTAAAAGCTGCCACAGGAACAAGTCCAACTTTTAATGGTGCAACAGTA
ACTGTCTATCACCAGCCAGCACCCATCGCTCAGTTGTCTCCAGCTGTTAGCCAGAAGCCTCCCTTCCAGTCAGGGTTTGGCAACAATCCC
TTCTCTTCCCTGGCCGGGAACTCCGACAGCTCATCCTCCCAGCCTCTGCGGACTGAGAATCGAGAGCCCCTCCCTAACCCCTGGAGCCCC
TCGCCCCCCACCTCCCAGGCCCCCGGGTCCGGTGGGGAGGGCACCGGAGGATCGGGGACCAGCCAGGTGCACCCGACAGTCTCGAACCCC
TTTGGGATCAATGCGGCTAGCCTGGGGTCAGGGATGTTCAATAGCCCAGAAATGCAAGCCCTCCTCCAGCAGATCTCTGAGAACCCCCAG
CTGATGCAGAATGTGATCTCAGCACCCTACATGCGCAGCATGATGCAGACGCTTGCCCAGAACCCCGACTTTGCTGCTCAGATGATGGTG
AATGTGCCGCTCTTCGCGGGGAACCCCCAACTGCAGGAGCAGCTCCGCCTGCAGCTCCCAGTCTTCCTGCAGCAGATGCAGAACCCAGAG
TCACTCTCCATCCTTACCAATCCCCGAGCCATGCAGGCATTGCTGCAGATCCAGCAGGGACTACAGACCTTGCAGACCGAGGCCCCTGGG
CTGGTACCCAGCCTTGGCTCCTTTGGGATATCCCGGACCCCAGCACCCTCAGCAGGCAGCAACGCAGGGTCTACGCCCGAGGCCCCCACT
TCCTCACCAGCCACGCCAGCCACATCTTCTCCAACAGGGGCTTCCAGCGCCCAGCAGCAACTCATGCAGCAGATGATCCAGCTTTTGGCT
GGAAGTGGAAACTCACAGGTGCAGACGCCAGAAGTGAGATTTCAGCAGCAGCTGGAGCAGCTCAACTCCATGGGCTTCATCAATCGTGAG
GCTAACCTGCAGGCCCTGATTGCCACAGGAGGGGACATCAACGCAGCTATCGAGAGACTGCTGGGCTCCCAGCTCTCCTAATCCCTCGGC
CCATGCCTCCTGCCTCTCCCCTCCCTCGATGTCAGCATTCGGTTCTTCTGTCAATCCTTACCCTCTGCAGCTTGTCCTCCCTTCCGTCTT
CTCCCTCATCCTTTCCAAACAGCAGGGTGACTTTAGAGGCATGGGCTCCAACCCCTTAGCTCTGTCTGAGAATTATGGTTTTACTGCTAC
GTCTCTAACAGACTCTTCTCTCCTGGTCTCCTTGAGCAGTGCTACTTAAACAGTTTTCACAGTTTCATTGATTGACTCTACCTCCTTGCC
CCACACCACTTTTGCAATCTTTAAACTTTCAGTGGCTGTGCAGAGTCGAGGGAGGAACCAGCTCTCTGGTTTACTGGAACATAGTCTTCC
ATCTATACCACTAGGGTTTTGTCTTATGTTTACTTTTGGTAACTCTCTTCCTTCTTTTTCTCCCTACCCCCCAACCCCTAGCCCAACCAA
TGCTAGAATTTCTTGCTCTGAAGGAGGAGCAGGTGAAACAGGTGGTAATTTTCCTTCTCGGCCCCTATTCTGGTTCATTCAGCACTTTTT
GGTGGGAACTGTTGGAAATTCCAGGGTAAGGAGGAAGATGCCTGTTCTCCCTGTCTGAAGAGGGAGATGAGACAGCTCTCTGGACAGGAA
TTAACAAACGCTGGAGCAGCCCAGAGGAAATTCGTGTGAAAGAGGAGGGAATGAGATTATTCGGAGGAAGGGAATGGGGGAGACAGCCTG
AGTAAAAGGCTTGGAAGTTGGAATTAACAGTGGGGAGCAGAAGCACTCATAGCTCTTTTAGGCAGAAGAATCCAGGCCCGAGCTGGCAGA
AGAGACTTAGAGATGCTAATGGAATTTAAACTGAAAAAAGGAGCCCAATGAAGCTAAGCGCCACGCCCCACAAGGGGTCATATTGGCTTT
AGTTCCTCAAGCATATGTGCTTATATGCACACACACACACATTTCCATGGACCCAGGTCTTGCTTGTGTCCCCAGGCACCAGTAGTTTGA
GCCCCCCTCAAAAGACATGAAGGGGGTTGGGGTCTGTGTGAGTAGTGGGGAGGTGCATGTGTATCCACATGTGTGCATACACTCTTAAGT
TGGGTGGGAAGTGGATTCCTTGTTGGTTTCTGGTTCAGAGTGCTCTCCCACCACCAGAGACAAGTGGGTAAAAAGGTCAGTCCATTGCAG
GAATATATATCCGGGAGAGCTAGGTCCCTTGGGGCTCTGGATGCTGGGTAACCCAGAGGTAATGTGGGTACCCTTTCTGAAGCTGTCAGG
GCTGTGACTAGCACCCTTATCACCCCTCACTGCCTTGTGGGAATAGTAGAGGGTTTTTTTCCTCCAGAGCCCCTGGCCTTTCAGTTCTTA
ACTATTTCCCTCCAGGCCAGAAAGTTTTCTTTGAGGAAGGAGAGGAGAGGGTGGCAATGATGCCTTTGATCTGGAATTGGACATTTCTCT
GTCAGAGCACAGAGGAGGCTCATATCACCTCTTCCCTCTCCTACTTGGCCCAGCTGCTTGGAGGACCGACCCCATGGCTGAGAATATGAC
GGCAAGAGGAACAGAGTTTGCTCCAAGTGGGAAAGGGTCCCAAGCAGTCCAGAGAAGATGTCTGTGTGGCTTTCCCTCCCTGCCTCCCCC

>42199_42199_3_KIAA0907-UBQLN4_KIAA0907_chr1_155896466_ENST00000368321_UBQLN4_chr1_156014014_ENST00000368309_length(amino acids)=528AA_BP=225
MSAGSATHPGAGGRRSKWDQPAPAPLLFLPPAAPGGEVTSSGGSPGGTTAAPSGALDAAAAVAAKINAMLMAKGKLKPTQNASEKLQAPG
KGLTSNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTTEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKE
IITNGVVKAATGTSPTFNGATVTVYHQPAPIAQLSPAVSQKPPFQSGFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAP
GSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGN
PQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPAT

--------------------------------------------------------------
>42199_42199_4_KIAA0907-UBQLN4_KIAA0907_chr1_155896467_ENST00000368319_UBQLN4_chr1_156014014_ENST00000368309_length(transcript)=3264nt_BP=681nt
ATGTCCGCGGGGAGCGCGACACATCCTGGAGCTGGCGGGCGCCGCAGCAAATGGGACCAACCAGCTCCAGCCCCACTTCTCTTCCTCCCG
CCAGCGGCCCCAGGTGGGGAGGTCACCAGCAGTGGGGGAAGTCCTGGGGGCACCACAGCTGCTCCTTCAGGAGCCTTGGATGCTGCTGCT
GCTGTGGCTGCCAAGATTAATGCCATGCTCATGGCAAAAGGGAAGCTGAAACCAACTCAGAATGCTTCTGAGAAGCTTCAGGCTCCTGGC
AAAGGCCTAACTAGCAATAAAAGCAAGGATGACCTGGTGGTAGCTGAAGTAGAAATTAATGATGTGCCTCTCACATGTAGGAACTTGCTG
ACTCGAGGACAGACTCAAGACGAGATCAGCCGACTTAGTGGGGCTGCAGTATCAACTCGAGGGAGGTTCATGACAACTGAGGAAAAAGCC
AAAGTGGGACCAGGGGATCGTCCATTATATCTTCATGTTCAGGGCCAGACACGGGAATTAGTGGACAGAGCTGTAAACCGGATCAAAGAA
ATTATCACCAATGGAGTGGTAAAAGCTGCCACAGGAACAAGTCCAACTTTTAATGGTGCAACAGTAACTGTCTATCACCAGCCAGCACCC
ATCGCTCAGTTGTCTCCAGCTGTTAGCCAGAAGCCTCCCTTCCAGTCAGGGTTTGGCAACAATCCCTTCTCTTCCCTGGCCGGGAACTCC
GACAGCTCATCCTCCCAGCCTCTGCGGACTGAGAATCGAGAGCCCCTCCCTAACCCCTGGAGCCCCTCGCCCCCCACCTCCCAGGCCCCC
GGGTCCGGTGGGGAGGGCACCGGAGGATCGGGGACCAGCCAGGTGCACCCGACAGTCTCGAACCCCTTTGGGATCAATGCGGCTAGCCTG
GGGTCAGGGATGTTCAATAGCCCAGAAATGCAAGCCCTCCTCCAGCAGATCTCTGAGAACCCCCAGCTGATGCAGAATGTGATCTCAGCA
CCCTACATGCGCAGCATGATGCAGACGCTTGCCCAGAACCCCGACTTTGCTGCTCAGATGATGGTGAATGTGCCGCTCTTCGCGGGGAAC
CCCCAACTGCAGGAGCAGCTCCGCCTGCAGCTCCCAGTCTTCCTGCAGCAGATGCAGAACCCAGAGTCACTCTCCATCCTTACCAATCCC
CGAGCCATGCAGGCATTGCTGCAGATCCAGCAGGGACTACAGACCTTGCAGACCGAGGCCCCTGGGCTGGTACCCAGCCTTGGCTCCTTT
GGGATATCCCGGACCCCAGCACCCTCAGCAGGCAGCAACGCAGGGTCTACGCCCGAGGCCCCCACTTCCTCACCAGCCACGCCAGCCACA
TCTTCTCCAACAGGGGCTTCCAGCGCCCAGCAGCAACTCATGCAGCAGATGATCCAGCTTTTGGCTGGAAGTGGAAACTCACAGGTGCAG
ACGCCAGAAGTGAGATTTCAGCAGCAGCTGGAGCAGCTCAACTCCATGGGCTTCATCAATCGTGAGGCTAACCTGCAGGCCCTGATTGCC
ACAGGAGGGGACATCAACGCAGCTATCGAGAGACTGCTGGGCTCCCAGCTCTCCTAATCCCTCGGCCCATGCCTCCTGCCTCTCCCCTCC
CTCGATGTCAGCATTCGGTTCTTCTGTCAATCCTTACCCTCTGCAGCTTGTCCTCCCTTCCGTCTTCTCCCTCATCCTTTCCAAACAGCA
GGGTGACTTTAGAGGCATGGGCTCCAACCCCTTAGCTCTGTCTGAGAATTATGGTTTTACTGCTACGTCTCTAACAGACTCTTCTCTCCT
GGTCTCCTTGAGCAGTGCTACTTAAACAGTTTTCACAGTTTCATTGATTGACTCTACCTCCTTGCCCCACACCACTTTTGCAATCTTTAA
ACTTTCAGTGGCTGTGCAGAGTCGAGGGAGGAACCAGCTCTCTGGTTTACTGGAACATAGTCTTCCATCTATACCACTAGGGTTTTGTCT
TATGTTTACTTTTGGTAACTCTCTTCCTTCTTTTTCTCCCTACCCCCCAACCCCTAGCCCAACCAATGCTAGAATTTCTTGCTCTGAAGG
AGGAGCAGGTGAAACAGGTGGTAATTTTCCTTCTCGGCCCCTATTCTGGTTCATTCAGCACTTTTTGGTGGGAACTGTTGGAAATTCCAG
GGTAAGGAGGAAGATGCCTGTTCTCCCTGTCTGAAGAGGGAGATGAGACAGCTCTCTGGACAGGAATTAACAAACGCTGGAGCAGCCCAG
AGGAAATTCGTGTGAAAGAGGAGGGAATGAGATTATTCGGAGGAAGGGAATGGGGGAGACAGCCTGAGTAAAAGGCTTGGAAGTTGGAAT
TAACAGTGGGGAGCAGAAGCACTCATAGCTCTTTTAGGCAGAAGAATCCAGGCCCGAGCTGGCAGAAGAGACTTAGAGATGCTAATGGAA
TTTAAACTGAAAAAAGGAGCCCAATGAAGCTAAGCGCCACGCCCCACAAGGGGTCATATTGGCTTTAGTTCCTCAAGCATATGTGCTTAT
ATGCACACACACACACATTTCCATGGACCCAGGTCTTGCTTGTGTCCCCAGGCACCAGTAGTTTGAGCCCCCCTCAAAAGACATGAAGGG
GGTTGGGGTCTGTGTGAGTAGTGGGGAGGTGCATGTGTATCCACATGTGTGCATACACTCTTAAGTTGGGTGGGAAGTGGATTCCTTGTT
GGTTTCTGGTTCAGAGTGCTCTCCCACCACCAGAGACAAGTGGGTAAAAAGGTCAGTCCATTGCAGGAATATATATCCGGGAGAGCTAGG
TCCCTTGGGGCTCTGGATGCTGGGTAACCCAGAGGTAATGTGGGTACCCTTTCTGAAGCTGTCAGGGCTGTGACTAGCACCCTTATCACC
CCTCACTGCCTTGTGGGAATAGTAGAGGGTTTTTTTCCTCCAGAGCCCCTGGCCTTTCAGTTCTTAACTATTTCCCTCCAGGCCAGAAAG
TTTTCTTTGAGGAAGGAGAGGAGAGGGTGGCAATGATGCCTTTGATCTGGAATTGGACATTTCTCTGTCAGAGCACAGAGGAGGCTCATA
TCACCTCTTCCCTCTCCTACTTGGCCCAGCTGCTTGGAGGACCGACCCCATGGCTGAGAATATGACGGCAAGAGGAACAGAGTTTGCTCC
AAGTGGGAAAGGGTCCCAAGCAGTCCAGAGAAGATGTCTGTGTGGCTTTCCCTCCCTGCCTCCCCCAGCTCCCACACTGGCCTTTGTAAA

>42199_42199_4_KIAA0907-UBQLN4_KIAA0907_chr1_155896467_ENST00000368319_UBQLN4_chr1_156014014_ENST00000368309_length(amino acids)=528AA_BP=225
MSAGSATHPGAGGRRSKWDQPAPAPLLFLPPAAPGGEVTSSGGSPGGTTAAPSGALDAAAAVAAKINAMLMAKGKLKPTQNASEKLQAPG
KGLTSNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTTEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKE
IITNGVVKAATGTSPTFNGATVTVYHQPAPIAQLSPAVSQKPPFQSGFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAP
GSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGN
PQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPAT

--------------------------------------------------------------
>42199_42199_5_KIAA0907-UBQLN4_KIAA0907_chr1_155896467_ENST00000368320_UBQLN4_chr1_156014014_ENST00000368309_length(transcript)=3290nt_BP=707nt
CGGGTGGTTGAGTAGAAGCGGTCGCCATGTCCGCGGGGAGCGCGACACATCCTGGAGCTGGCGGGCGCCGCAGCAAATGGGACCAACCAG
CTCCAGCCCCACTTCTCTTCCTCCCGCCAGCGGCCCCAGGTGGGGAGGTCACCAGCAGTGGGGGAAGTCCTGGGGGCACCACAGCTGCTC
CTTCAGGAGCCTTGGATGCTGCTGCTGCTGTGGCTGCCAAGATTAATGCCATGCTCATGGCAAAAGGGAAGCTGAAACCAACTCAGAATG
CTTCTGAGAAGCTTCAGGCTCCTGGCAAAGGCCTAACTAGCAATAAAAGCAAGGATGACCTGGTGGTAGCTGAAGTAGAAATTAATGATG
TGCCTCTCACATGTAGGAACTTGCTGACTCGAGGACAGACTCAAGACGAGATCAGCCGACTTAGTGGGGCTGCAGTATCAACTCGAGGGA
GGTTCATGACAACTGAGGAAAAAGCCAAAGTGGGACCAGGGGATCGTCCATTATATCTTCATGTTCAGGGCCAGACACGGGAATTAGTGG
ACAGAGCTGTAAACCGGATCAAAGAAATTATCACCAATGGAGTGGTAAAAGCTGCCACAGGAACAAGTCCAACTTTTAATGGTGCAACAG
TAACTGTCTATCACCAGCCAGCACCCATCGCTCAGTTGTCTCCAGCTGTTAGCCAGAAGCCTCCCTTCCAGTCAGGGTTTGGCAACAATC
CCTTCTCTTCCCTGGCCGGGAACTCCGACAGCTCATCCTCCCAGCCTCTGCGGACTGAGAATCGAGAGCCCCTCCCTAACCCCTGGAGCC
CCTCGCCCCCCACCTCCCAGGCCCCCGGGTCCGGTGGGGAGGGCACCGGAGGATCGGGGACCAGCCAGGTGCACCCGACAGTCTCGAACC
CCTTTGGGATCAATGCGGCTAGCCTGGGGTCAGGGATGTTCAATAGCCCAGAAATGCAAGCCCTCCTCCAGCAGATCTCTGAGAACCCCC
AGCTGATGCAGAATGTGATCTCAGCACCCTACATGCGCAGCATGATGCAGACGCTTGCCCAGAACCCCGACTTTGCTGCTCAGATGATGG
TGAATGTGCCGCTCTTCGCGGGGAACCCCCAACTGCAGGAGCAGCTCCGCCTGCAGCTCCCAGTCTTCCTGCAGCAGATGCAGAACCCAG
AGTCACTCTCCATCCTTACCAATCCCCGAGCCATGCAGGCATTGCTGCAGATCCAGCAGGGACTACAGACCTTGCAGACCGAGGCCCCTG
GGCTGGTACCCAGCCTTGGCTCCTTTGGGATATCCCGGACCCCAGCACCCTCAGCAGGCAGCAACGCAGGGTCTACGCCCGAGGCCCCCA
CTTCCTCACCAGCCACGCCAGCCACATCTTCTCCAACAGGGGCTTCCAGCGCCCAGCAGCAACTCATGCAGCAGATGATCCAGCTTTTGG
CTGGAAGTGGAAACTCACAGGTGCAGACGCCAGAAGTGAGATTTCAGCAGCAGCTGGAGCAGCTCAACTCCATGGGCTTCATCAATCGTG
AGGCTAACCTGCAGGCCCTGATTGCCACAGGAGGGGACATCAACGCAGCTATCGAGAGACTGCTGGGCTCCCAGCTCTCCTAATCCCTCG
GCCCATGCCTCCTGCCTCTCCCCTCCCTCGATGTCAGCATTCGGTTCTTCTGTCAATCCTTACCCTCTGCAGCTTGTCCTCCCTTCCGTC
TTCTCCCTCATCCTTTCCAAACAGCAGGGTGACTTTAGAGGCATGGGCTCCAACCCCTTAGCTCTGTCTGAGAATTATGGTTTTACTGCT
ACGTCTCTAACAGACTCTTCTCTCCTGGTCTCCTTGAGCAGTGCTACTTAAACAGTTTTCACAGTTTCATTGATTGACTCTACCTCCTTG
CCCCACACCACTTTTGCAATCTTTAAACTTTCAGTGGCTGTGCAGAGTCGAGGGAGGAACCAGCTCTCTGGTTTACTGGAACATAGTCTT
CCATCTATACCACTAGGGTTTTGTCTTATGTTTACTTTTGGTAACTCTCTTCCTTCTTTTTCTCCCTACCCCCCAACCCCTAGCCCAACC
AATGCTAGAATTTCTTGCTCTGAAGGAGGAGCAGGTGAAACAGGTGGTAATTTTCCTTCTCGGCCCCTATTCTGGTTCATTCAGCACTTT
TTGGTGGGAACTGTTGGAAATTCCAGGGTAAGGAGGAAGATGCCTGTTCTCCCTGTCTGAAGAGGGAGATGAGACAGCTCTCTGGACAGG
AATTAACAAACGCTGGAGCAGCCCAGAGGAAATTCGTGTGAAAGAGGAGGGAATGAGATTATTCGGAGGAAGGGAATGGGGGAGACAGCC
TGAGTAAAAGGCTTGGAAGTTGGAATTAACAGTGGGGAGCAGAAGCACTCATAGCTCTTTTAGGCAGAAGAATCCAGGCCCGAGCTGGCA
GAAGAGACTTAGAGATGCTAATGGAATTTAAACTGAAAAAAGGAGCCCAATGAAGCTAAGCGCCACGCCCCACAAGGGGTCATATTGGCT
TTAGTTCCTCAAGCATATGTGCTTATATGCACACACACACACATTTCCATGGACCCAGGTCTTGCTTGTGTCCCCAGGCACCAGTAGTTT
GAGCCCCCCTCAAAAGACATGAAGGGGGTTGGGGTCTGTGTGAGTAGTGGGGAGGTGCATGTGTATCCACATGTGTGCATACACTCTTAA
GTTGGGTGGGAAGTGGATTCCTTGTTGGTTTCTGGTTCAGAGTGCTCTCCCACCACCAGAGACAAGTGGGTAAAAAGGTCAGTCCATTGC
AGGAATATATATCCGGGAGAGCTAGGTCCCTTGGGGCTCTGGATGCTGGGTAACCCAGAGGTAATGTGGGTACCCTTTCTGAAGCTGTCA
GGGCTGTGACTAGCACCCTTATCACCCCTCACTGCCTTGTGGGAATAGTAGAGGGTTTTTTTCCTCCAGAGCCCCTGGCCTTTCAGTTCT
TAACTATTTCCCTCCAGGCCAGAAAGTTTTCTTTGAGGAAGGAGAGGAGAGGGTGGCAATGATGCCTTTGATCTGGAATTGGACATTTCT
CTGTCAGAGCACAGAGGAGGCTCATATCACCTCTTCCCTCTCCTACTTGGCCCAGCTGCTTGGAGGACCGACCCCATGGCTGAGAATATG
ACGGCAAGAGGAACAGAGTTTGCTCCAAGTGGGAAAGGGTCCCAAGCAGTCCAGAGAAGATGTCTGTGTGGCTTTCCCTCCCTGCCTCCC

>42199_42199_5_KIAA0907-UBQLN4_KIAA0907_chr1_155896467_ENST00000368320_UBQLN4_chr1_156014014_ENST00000368309_length(amino acids)=528AA_BP=225
MSAGSATHPGAGGRRSKWDQPAPAPLLFLPPAAPGGEVTSSGGSPGGTTAAPSGALDAAAAVAAKINAMLMAKGKLKPTQNASEKLQAPG
KGLTSNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTTEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKE
IITNGVVKAATGTSPTFNGATVTVYHQPAPIAQLSPAVSQKPPFQSGFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAP
GSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGN
PQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPAT

--------------------------------------------------------------
>42199_42199_6_KIAA0907-UBQLN4_KIAA0907_chr1_155896467_ENST00000368321_UBQLN4_chr1_156014014_ENST00000368309_length(transcript)=3288nt_BP=705nt
GGTGGTTGAGTAGAAGCGGTCGCCATGTCCGCGGGGAGCGCGACACATCCTGGAGCTGGCGGGCGCCGCAGCAAATGGGACCAACCAGCT
CCAGCCCCACTTCTCTTCCTCCCGCCAGCGGCCCCAGGTGGGGAGGTCACCAGCAGTGGGGGAAGTCCTGGGGGCACCACAGCTGCTCCT
TCAGGAGCCTTGGATGCTGCTGCTGCTGTGGCTGCCAAGATTAATGCCATGCTCATGGCAAAAGGGAAGCTGAAACCAACTCAGAATGCT
TCTGAGAAGCTTCAGGCTCCTGGCAAAGGCCTAACTAGCAATAAAAGCAAGGATGACCTGGTGGTAGCTGAAGTAGAAATTAATGATGTG
CCTCTCACATGTAGGAACTTGCTGACTCGAGGACAGACTCAAGACGAGATCAGCCGACTTAGTGGGGCTGCAGTATCAACTCGAGGGAGG
TTCATGACAACTGAGGAAAAAGCCAAAGTGGGACCAGGGGATCGTCCATTATATCTTCATGTTCAGGGCCAGACACGGGAATTAGTGGAC
AGAGCTGTAAACCGGATCAAAGAAATTATCACCAATGGAGTGGTAAAAGCTGCCACAGGAACAAGTCCAACTTTTAATGGTGCAACAGTA
ACTGTCTATCACCAGCCAGCACCCATCGCTCAGTTGTCTCCAGCTGTTAGCCAGAAGCCTCCCTTCCAGTCAGGGTTTGGCAACAATCCC
TTCTCTTCCCTGGCCGGGAACTCCGACAGCTCATCCTCCCAGCCTCTGCGGACTGAGAATCGAGAGCCCCTCCCTAACCCCTGGAGCCCC
TCGCCCCCCACCTCCCAGGCCCCCGGGTCCGGTGGGGAGGGCACCGGAGGATCGGGGACCAGCCAGGTGCACCCGACAGTCTCGAACCCC
TTTGGGATCAATGCGGCTAGCCTGGGGTCAGGGATGTTCAATAGCCCAGAAATGCAAGCCCTCCTCCAGCAGATCTCTGAGAACCCCCAG
CTGATGCAGAATGTGATCTCAGCACCCTACATGCGCAGCATGATGCAGACGCTTGCCCAGAACCCCGACTTTGCTGCTCAGATGATGGTG
AATGTGCCGCTCTTCGCGGGGAACCCCCAACTGCAGGAGCAGCTCCGCCTGCAGCTCCCAGTCTTCCTGCAGCAGATGCAGAACCCAGAG
TCACTCTCCATCCTTACCAATCCCCGAGCCATGCAGGCATTGCTGCAGATCCAGCAGGGACTACAGACCTTGCAGACCGAGGCCCCTGGG
CTGGTACCCAGCCTTGGCTCCTTTGGGATATCCCGGACCCCAGCACCCTCAGCAGGCAGCAACGCAGGGTCTACGCCCGAGGCCCCCACT
TCCTCACCAGCCACGCCAGCCACATCTTCTCCAACAGGGGCTTCCAGCGCCCAGCAGCAACTCATGCAGCAGATGATCCAGCTTTTGGCT
GGAAGTGGAAACTCACAGGTGCAGACGCCAGAAGTGAGATTTCAGCAGCAGCTGGAGCAGCTCAACTCCATGGGCTTCATCAATCGTGAG
GCTAACCTGCAGGCCCTGATTGCCACAGGAGGGGACATCAACGCAGCTATCGAGAGACTGCTGGGCTCCCAGCTCTCCTAATCCCTCGGC
CCATGCCTCCTGCCTCTCCCCTCCCTCGATGTCAGCATTCGGTTCTTCTGTCAATCCTTACCCTCTGCAGCTTGTCCTCCCTTCCGTCTT
CTCCCTCATCCTTTCCAAACAGCAGGGTGACTTTAGAGGCATGGGCTCCAACCCCTTAGCTCTGTCTGAGAATTATGGTTTTACTGCTAC
GTCTCTAACAGACTCTTCTCTCCTGGTCTCCTTGAGCAGTGCTACTTAAACAGTTTTCACAGTTTCATTGATTGACTCTACCTCCTTGCC
CCACACCACTTTTGCAATCTTTAAACTTTCAGTGGCTGTGCAGAGTCGAGGGAGGAACCAGCTCTCTGGTTTACTGGAACATAGTCTTCC
ATCTATACCACTAGGGTTTTGTCTTATGTTTACTTTTGGTAACTCTCTTCCTTCTTTTTCTCCCTACCCCCCAACCCCTAGCCCAACCAA
TGCTAGAATTTCTTGCTCTGAAGGAGGAGCAGGTGAAACAGGTGGTAATTTTCCTTCTCGGCCCCTATTCTGGTTCATTCAGCACTTTTT
GGTGGGAACTGTTGGAAATTCCAGGGTAAGGAGGAAGATGCCTGTTCTCCCTGTCTGAAGAGGGAGATGAGACAGCTCTCTGGACAGGAA
TTAACAAACGCTGGAGCAGCCCAGAGGAAATTCGTGTGAAAGAGGAGGGAATGAGATTATTCGGAGGAAGGGAATGGGGGAGACAGCCTG
AGTAAAAGGCTTGGAAGTTGGAATTAACAGTGGGGAGCAGAAGCACTCATAGCTCTTTTAGGCAGAAGAATCCAGGCCCGAGCTGGCAGA
AGAGACTTAGAGATGCTAATGGAATTTAAACTGAAAAAAGGAGCCCAATGAAGCTAAGCGCCACGCCCCACAAGGGGTCATATTGGCTTT
AGTTCCTCAAGCATATGTGCTTATATGCACACACACACACATTTCCATGGACCCAGGTCTTGCTTGTGTCCCCAGGCACCAGTAGTTTGA
GCCCCCCTCAAAAGACATGAAGGGGGTTGGGGTCTGTGTGAGTAGTGGGGAGGTGCATGTGTATCCACATGTGTGCATACACTCTTAAGT
TGGGTGGGAAGTGGATTCCTTGTTGGTTTCTGGTTCAGAGTGCTCTCCCACCACCAGAGACAAGTGGGTAAAAAGGTCAGTCCATTGCAG
GAATATATATCCGGGAGAGCTAGGTCCCTTGGGGCTCTGGATGCTGGGTAACCCAGAGGTAATGTGGGTACCCTTTCTGAAGCTGTCAGG
GCTGTGACTAGCACCCTTATCACCCCTCACTGCCTTGTGGGAATAGTAGAGGGTTTTTTTCCTCCAGAGCCCCTGGCCTTTCAGTTCTTA
ACTATTTCCCTCCAGGCCAGAAAGTTTTCTTTGAGGAAGGAGAGGAGAGGGTGGCAATGATGCCTTTGATCTGGAATTGGACATTTCTCT
GTCAGAGCACAGAGGAGGCTCATATCACCTCTTCCCTCTCCTACTTGGCCCAGCTGCTTGGAGGACCGACCCCATGGCTGAGAATATGAC
GGCAAGAGGAACAGAGTTTGCTCCAAGTGGGAAAGGGTCCCAAGCAGTCCAGAGAAGATGTCTGTGTGGCTTTCCCTCCCTGCCTCCCCC

>42199_42199_6_KIAA0907-UBQLN4_KIAA0907_chr1_155896467_ENST00000368321_UBQLN4_chr1_156014014_ENST00000368309_length(amino acids)=528AA_BP=225
MSAGSATHPGAGGRRSKWDQPAPAPLLFLPPAAPGGEVTSSGGSPGGTTAAPSGALDAAAAVAAKINAMLMAKGKLKPTQNASEKLQAPG
KGLTSNKSKDDLVVAEVEINDVPLTCRNLLTRGQTQDEISRLSGAAVSTRGRFMTTEEKAKVGPGDRPLYLHVQGQTRELVDRAVNRIKE
IITNGVVKAATGTSPTFNGATVTVYHQPAPIAQLSPAVSQKPPFQSGFGNNPFSSLAGNSDSSSSQPLRTENREPLPNPWSPSPPTSQAP
GSGGEGTGGSGTSQVHPTVSNPFGINAASLGSGMFNSPEMQALLQQISENPQLMQNVISAPYMRSMMQTLAQNPDFAAQMMVNVPLFAGN
PQLQEQLRLQLPVFLQQMQNPESLSILTNPRAMQALLQIQQGLQTLQTEAPGLVPSLGSFGISRTPAPSAGSNAGSTPEAPTSSPATPAT

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Fusion Gene PPI Analysis for KIAA0907-UBQLN4


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KIAA0907-UBQLN4


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KIAA0907-UBQLN4


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource