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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KIAA1328-LIMCH1 (FusionGDB2 ID:42322)

Fusion Gene Summary for KIAA1328-LIMCH1

check button Fusion gene summary
Fusion gene informationFusion gene name: KIAA1328-LIMCH1
Fusion gene ID: 42322
HgeneTgene
Gene symbol

KIAA1328

LIMCH1

Gene ID

57536

22998

Gene nameKIAA1328LIM and calponin homology domains 1
Synonyms-LIMCH1A|LMO7B
Cytomap

18q12.2

4p13

Type of geneprotein-codingprotein-coding
Descriptionprotein hinderinhinderinLIM and calponin homology domains-containing protein 1
Modification date2020031320200313
UniProtAcc.

Q9UPQ0

Ensembl transtripts involved in fusion geneENST00000280020, ENST00000543923, 
ENST00000591619, ENST00000435985, 
ENST00000586135, ENST00000586501, 
ENST00000592521, ENST00000601437, 
ENST00000313860, ENST00000381753, 
ENST00000396595, ENST00000503057, 
ENST00000508501, ENST00000509277, 
ENST00000509454, ENST00000509638, 
ENST00000511496, ENST00000512632, 
ENST00000512820, ENST00000512946, 
ENST00000514096, ENST00000515785, 
ENST00000513024, 
Fusion gene scores* DoF score7 X 7 X 5=24518 X 19 X 9=3078
# samples 719
** MAII scorelog2(7/245*10)=-1.8073549220576
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/3078*10)=-4.01792190799726
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KIAA1328 [Title/Abstract] AND LIMCH1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKIAA1328(34539398)-LIMCH1(41663437), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across KIAA1328 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LIMCH1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LGGTCGA-DU-6407-02BKIAA1328chr18

34539398

-LIMCH1chr4

41663437

+


Top

Fusion Gene ORF analysis for KIAA1328-LIMCH1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000280020ENST00000313860KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000381753KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000396595KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000503057KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000508501KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000509277KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000509454KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000509638KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000511496KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000512632KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000512820KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000512946KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000514096KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000280020ENST00000515785KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000313860KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000381753KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000396595KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000503057KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000508501KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000509277KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000509454KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000509638KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000511496KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000512632KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000512820KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000512946KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000514096KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000543923ENST00000515785KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000313860KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000381753KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000396595KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000503057KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000508501KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000509277KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000509454KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000509638KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000511496KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000512632KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000512820KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000512946KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000514096KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5CDS-intronENST00000591619ENST00000515785KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-3CDSENST00000435985ENST00000513024KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000313860KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000381753KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000396595KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000503057KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000508501KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000509277KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000509454KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000509638KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000511496KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000512632KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000512820KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000512946KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000514096KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
5UTR-intronENST00000435985ENST00000515785KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
In-frameENST00000280020ENST00000513024KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
In-frameENST00000543923ENST00000513024KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
In-frameENST00000591619ENST00000513024KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-3CDSENST00000586135ENST00000513024KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-3CDSENST00000586501ENST00000513024KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-3CDSENST00000592521ENST00000513024KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-3CDSENST00000601437ENST00000513024KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000313860KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000381753KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000396595KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000503057KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000508501KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000509277KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000509454KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000509638KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000511496KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000512632KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000512820KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000512946KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000514096KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586135ENST00000515785KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000313860KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000381753KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000396595KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000503057KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000508501KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000509277KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000509454KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000509638KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000511496KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000512632KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000512820KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000512946KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000514096KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000586501ENST00000515785KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000313860KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000381753KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000396595KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000503057KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000508501KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000509277KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000509454KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000509638KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000511496KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000512632KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000512820KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000512946KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000514096KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000592521ENST00000515785KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000313860KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000381753KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000396595KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000503057KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000508501KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000509277KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000509454KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000509638KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000511496KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000512632KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000512820KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000512946KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000514096KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+
intron-intronENST00000601437ENST00000515785KIAA1328chr18

34539398

-LIMCH1chr4

41663437

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000543923KIAA1328chr1834539398-ENST00000513024LIMCH1chr441663437+36975142621878538
ENST00000280020KIAA1328chr1834539398-ENST00000513024LIMCH1chr441663437+3781598221962646
ENST00000591619KIAA1328chr1834539398-ENST00000513024LIMCH1chr441663437+453313507862714642

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000543923ENST00000513024KIAA1328chr1834539398-LIMCH1chr441663437+0.0006544750.9993455
ENST00000280020ENST00000513024KIAA1328chr1834539398-LIMCH1chr441663437+0.0005788460.9994211
ENST00000591619ENST00000513024KIAA1328chr1834539398-LIMCH1chr441663437+0.0012032790.9987967

Top

Fusion Genomic Features for KIAA1328-LIMCH1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KIAA1328-LIMCH1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:34539398/chr4:41663437)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.LIMCH1

Q9UPQ0

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Actin stress fibers-associated protein that activates non-muscle myosin IIa. Activates the non-muscle myosin IIa complex by promoting the phosphorylation of its regulatory subunit MRLC/MYL9. Through the activation of non-muscle myosin IIa, positively regulates actin stress fibers assembly and stabilizes focal adhesions. It therefore negatively regulates cell spreading and cell migration. {ECO:0000269|PubMed:28228547}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000280020-61091_167192578.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000591619-61191_167188441.3333333333333Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000003138601227782_8236271084.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000381753620782_823461891.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000396595721782_823473903.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000005085011226782_8236271057.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000511496923782_823468898.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000005128201126782_8236151070.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000005129461226782_8236271058.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000005130241126782_823456911.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST0000031386012271011_10776271084.0DomainLIM zinc-binding
TgeneLIMCH1chr18:34539398chr4:41663437ENST000003817536201011_1077461891.0DomainLIM zinc-binding
TgeneLIMCH1chr18:34539398chr4:41663437ENST000003965957211011_1077473903.0DomainLIM zinc-binding
TgeneLIMCH1chr18:34539398chr4:41663437ENST0000050850112261011_10776271057.0DomainLIM zinc-binding
TgeneLIMCH1chr18:34539398chr4:41663437ENST000005114969231011_1077468898.0DomainLIM zinc-binding
TgeneLIMCH1chr18:34539398chr4:41663437ENST0000051282011261011_10776151070.0DomainLIM zinc-binding
TgeneLIMCH1chr18:34539398chr4:41663437ENST0000051294612261011_10776271058.0DomainLIM zinc-binding
TgeneLIMCH1chr18:34539398chr4:41663437ENST0000051302411261011_1077456911.0DomainLIM zinc-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000280020-610358_402192578.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000435985-611358_4020280.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000435985-61191_1670280.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000586135-19358_4020369.3333333333333Coiled coilOntology_term=ECO:0000255
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000586135-1991_1670369.3333333333333Coiled coilOntology_term=ECO:0000255
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000586501-12358_4020130.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000586501-1291_1670130.0Coiled coilOntology_term=ECO:0000255
HgeneKIAA1328chr18:34539398chr4:41663437ENST00000591619-611358_402188441.3333333333333Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000003138601227354_4396271084.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000381753620354_439461891.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000396595721354_439473903.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000005085011226354_4396271057.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000511496923354_439468898.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000005128201126354_4396151070.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000005129461226354_4396271058.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST000005130241126354_439456911.0Coiled coilOntology_term=ECO:0000255
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000313860122721_1256271084.0DomainCalponin-homology (CH)
TgeneLIMCH1chr18:34539398chr4:41663437ENST0000038175362021_125461891.0DomainCalponin-homology (CH)
TgeneLIMCH1chr18:34539398chr4:41663437ENST0000039659572121_125473903.0DomainCalponin-homology (CH)
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000508501122621_1256271057.0DomainCalponin-homology (CH)
TgeneLIMCH1chr18:34539398chr4:41663437ENST0000051149692321_125468898.0DomainCalponin-homology (CH)
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000512820112621_1256151070.0DomainCalponin-homology (CH)
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000512946122621_1256271058.0DomainCalponin-homology (CH)
TgeneLIMCH1chr18:34539398chr4:41663437ENST00000513024112621_125456911.0DomainCalponin-homology (CH)


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Fusion Gene Sequence for KIAA1328-LIMCH1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42322_42322_1_KIAA1328-LIMCH1_KIAA1328_chr18_34539398_ENST00000280020_LIMCH1_chr4_41663437_ENST00000513024_length(transcript)=3781nt_BP=598nt
CCCGAGTGGCGGTTGTTTCAAGATGGCGGACGTGGCGGGCCCCTCCCGCCCCAGTGCCGCGGCGTTCTGGAGCCGGGACTTTTCTGATGA
AGAACAATCAGTAGTATACGTTCCAGGAATTTCTGCTGAAGGAAATGTCAGATCAAGACACAAGCTGATGAGTCCAAAAGCTGATGTTAA
ACTTAAGACTTCCAGGGTGACTGATGCTTCAATCTCCATGGAGTCCTTAAAAGGCACAGGAGATTCAGTAGATGAACAGAATTCCTGCAG
GGGAGAAATAAAGAGTGCATCATTGAAGGATTTATGTCTTGAAGACAAAAGACGCATTGCAAACTTAATTAAAGAACTGGCCAGAGTAAG
TGAGGAAAAGGAAGTGACAGAGGAAAGACTGAAAGCTGAGCAGGAGTCATTTGAGAAGAAGATCAGGCAGTTGGAAGAACAGAATGAACT
GATCATCAAAGAAAGGGAAGCTCTTCAGCTACAGTATAGAGAATGCCAAGAACTTCTAAGCCTGTATCAGAAATATTTATCAGAACAACA
GGAGAAGCTCACCATGTCTCTCTCAGAACTTGGTGCTGCTAGAATGCAGGAACAGCAGGCAACCACTGAGAAAACGGAACCGAATAGTCA
AGAGGACAAGAATGATGGTGGAAAATCAAGAAAAGGGAATATAGAACTTGCCTCATCAGAACCACAGCATTTTACAACAACTGTGACTCG
ATGCAGCCCGACCGTGGCCTTTGTGGAATTTCCCTCCAGCCCCCAGCTGAAGAATGATGTGTCGGAAGAAAAAGACCAGAAGAAACCAGA
AAATGAAATGAGTGGAAAGGTGGAGTTGGTGCTGTCACAAAAGGTGGTAAAGCCAAAATCTCCAGAACCCGAAGCAACGCTGACATTTCC
ATTTCTGGACAAAATGCCTGAAGCCAACCAACTACATTTGCCAAATCTCAATTCTCAAGAGTCGCCTGGCACTGCCAGTGTTCCGCTTAG
AGTTCAGAACTCTTGGCGACGATCCCAGTTTTTCTCCCAGTCAGTGGATTCTCCAAGCAGTGAGAAGTCACCTGTTATGACACCTTTTAA
GTTCTGGGCATGGGACCCAGAAGAGGAGCGCAGGCGACAGGAAAAATGGCAACAGGAACAGGAACGTTTGCTCCAGGAGAGATACCAGAA
GGAGCAGGACAAGCTGAAAGAAGAGTGGGAAAAGGCCCAAAAGGAGGTGGAAGAGGAAGAACGCAGATACTATGAGGAGGAGCGTAAGAT
AATTGAAGACACTGTGGTTCCATTTACTGTTTCTTCAAGTTCCGCTGACCAGCTGTCTACCTCTTCCTCCATGACTGAAGGCAGTGGGAC
AATGAATAAGATAGACCTGGGAAACTGTCAAGATGAAAAACAAGACAGAAGATGGAAGAAATCATTCCAGGGAGATGACAGTGACTTATT
GCTGAAGACTAGGGAAAGTGATCGACTGGAGGAGAAGGGCAGCCTAACTGAAGGGGCCTTGGCTCATTCTGGGAACCCTGTATCAAAAGG
AGTCCATGAAGACCATCAGCTGGATACCGAGGCTGGGGCCCCACACTGTGGAACAAACCCACAGCTTGCTCAGGATCCATCCCAGAATCA
GCAGACATCAAATCCAACGCACAGTTCAGAAGATGTGAAGCCAAAAACCCTCCCGCTGGATAAAAGCATTAACCATCAGATCGAGTCTCC
CAGTGAAAGGCGGAAGTCTATAAGTGGAAAGAAGCTGTGCTCTTCCTGTGGGCTTCCTTTGGGTAAAGGAGCTGCAATGATCATCGAGAC
CCTCAATCTCTATTTTCACATCCAGTGTTTCAGGTGTGGAATTTGTAAAGGCCAGCTTGGAGATGCAGTGAGTGGGACGGATGTTAGGAT
TCGAAATGGTCTCCTGAACTGTAATGATTGCTACATGCGATCCAGAAGTGCCGGGCAGCCTACAACATTGTGACACGGCTTTCAAGCTTC
CGGATCACTCACCATTTCTTTACTGAGAGTGTCCCCTGGCAACTGCTTAACAAAATCCCAAGCTCAGGGGCTTCTCAGCATTTACCTAAT
TTCTGAAAGGCTCTTCTGAAAGGTGGTATCTGTTCTTTCGTAGCACAGTGTTTATGTTTTTCCTGTTTATTGTTTTGGTTTTTTTTTTTT
TTTTGCATTTGCACAGTATACACAAAAGAATATGGGGTTGTAATGATCCTGAATAGCTCAAAAAAGGTTTTAGCATGGTCAAACAGGCTT
ATGGTTTAAAATGTGTTATTCTCTTCTTTGGGAATTAGCTAAATGATGCAATAAACCTGTTTTGTTTTAGAATGTCTAGGAATTAAACAC
TTTATGTTTACAGAATTGAGCTGCAGAAAGTGCAAGACATGCCAATTTGAGACACACGGTCTTCTAAGACTGAAGGATAAATTTAATGCA
TTTCAGAAACTAAACATCACAGCAAGCTCTATCTCTGAGCTATAATTTGTTTTTAATGCAAAGACACTAGTTTGATAATATATACTGTAA
TCCTGAAACATTTGTGTTACTTACCTTTGGAGGTAGAAATTATACCAATAAATTATTGCACCGTTAGTATTAGATTCTGTGTACCTTGGA
AGTTATGTCATTAATATAGGCTGGTTCATCAAATAAAGCAAAACCTTGCAATATCAGCTAGATTTACACTCCGGGACGTTGCCCAAAGGT
AGGAAGAAAGCAGAGGGAAATATTTCAGTCATCATTTCCAAAGTCATTATCAAAATCTGTGAGGAAGTTTAATCTTCCAAAGAGTCAATG
TCAGACATCAGGCCTCTGTTGCCTGCTTCTCTCGAGGCACTAGATTAGGAGTCTTCAATAAGAGACTTAACATGAGGTATATGGAAGATG
AGGCACCGAGATAAGTTCATCATTAGGTGTGAGCACTGCTCACCCTTGCTGGCAAGTTCTCCTTAAGGGCCTGAAGCACAGGTGTCCAAA
GAAAAGCGTTAAGTCCATCTTAATAGAATCTATGTGGTATATGATGTGGTCAGCCCCTGGTCTGTGATCAGCAAGAACCTACAGCACAGA
TTATGCCCTGCCCACTTCAATGAATACCTACTCTCCTCCATTCTCCATCACTTTTTTTGCTATCAAGAACTCCGGACCTTGCCCATGGAG
AAGTTTAGAGAGGAACTCTTGTGGAGAGCTGGTTTATTTTCTGCCCTGTGCGACGAGTTTCAGCTGGCCAAGAAAGGAGTCAAGTTATTA
AAAAGCATCACAATGTAGATCTCCAGGCTGGTTTTTTGTTTTTTGTTGTTAAGACTGGGGAAAGGGGGACTATTTATTCTGCCTTAAATC
AATGGCAAATAAGTCAAGATGACATTTTGTGAATGTAGACTATGGATACACTCCTAATAGATTGATGTAGTCATAAAAGGGGGTCAAGTA
GATGTTTTTCTGTTATGTAAGCAATAATTTTTCCGTGTCTTATTGAGTATGGCTAGCGATTATTTATTACATGCTAGATGGGTTCTTTGC
ATGTGGGTTCCATATAGGTGCAGAAATTTCCTCAGCCACTGGAGGGATTTCGACCATATTTGTCATTTGGATGAGCTGTTATTAGATTGA
AATCTACACATCATTTCATTAAAAATTGTGCCTTAGAAAACGCAAAGCTGTTGCACATGGCGATAAATTATGGATGCAGTACATTGAAGA
GAGATGAAGTCACTTCCAAGTTTCCAAGACTTCTCATGGAGGTGTTTGCTGTTTTACAGGAAAAAATAAAAATAAAAAAAGAAAAAAAGA

>42322_42322_1_KIAA1328-LIMCH1_KIAA1328_chr18_34539398_ENST00000280020_LIMCH1_chr4_41663437_ENST00000513024_length(amino acids)=646AA_BP=191
MADVAGPSRPSAAAFWSRDFSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSAS
LKDLCLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSL
SELGAARMQEQQATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKV
ELVLSQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQESPGTASVPLRVQNSWRRSQFFSQSVDSPSSEKSPVMTPFKFWAWDPE
EERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLG
NCQDEKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTH
SSEDVKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNC

--------------------------------------------------------------
>42322_42322_2_KIAA1328-LIMCH1_KIAA1328_chr18_34539398_ENST00000543923_LIMCH1_chr4_41663437_ENST00000513024_length(transcript)=3697nt_BP=514nt
AGGCGCGACGCCCCGAGTGGCGGTTGTTTCAAGATGGCGGACGTGGCGGGCCCCTCCCGCCCCAGTGCCGCGGCGTTCTGGAGCCGGGAC
TTTTCTGATGAAGAACAATCAGTAGTATACGTTCCAGGAATTTCTGCTGAAGGAAATGTCAGATCAAGACACAAGCTGATGAGTCCAAAA
GCTGATGTTAAACTTAAGACTTCCAGGGTGACTGATGCTTCAATCTCCATGGAGTCCTTAAAAGGCACAGGAGATTCAGTAGATGAACAG
AGTAAGTGAGGAAAAGGAAGTGACAGAGGAAAGACTGAAAGCTGAGCAGGAGTCATTTGAGAAGAAGATCAGGCAGTTGGAAGAACAGAA
TGAACTGATCATCAAAGAAAGGGAAGCTCTTCAGCTACAGTATAGAGAATGCCAAGAACTTCTAAGCCTGTATCAGAAATATTTATCAGA
ACAACAGGAGAAGCTCACCATGTCTCTCTCAGAACTTGGTGCTGCTAGAATGCAGGAACAGCAGGCAACCACTGAGAAAACGGAACCGAA
TAGTCAAGAGGACAAGAATGATGGTGGAAAATCAAGAAAAGGGAATATAGAACTTGCCTCATCAGAACCACAGCATTTTACAACAACTGT
GACTCGATGCAGCCCGACCGTGGCCTTTGTGGAATTTCCCTCCAGCCCCCAGCTGAAGAATGATGTGTCGGAAGAAAAAGACCAGAAGAA
ACCAGAAAATGAAATGAGTGGAAAGGTGGAGTTGGTGCTGTCACAAAAGGTGGTAAAGCCAAAATCTCCAGAACCCGAAGCAACGCTGAC
ATTTCCATTTCTGGACAAAATGCCTGAAGCCAACCAACTACATTTGCCAAATCTCAATTCTCAAGAGTCGCCTGGCACTGCCAGTGTTCC
GCTTAGAGTTCAGAACTCTTGGCGACGATCCCAGTTTTTCTCCCAGTCAGTGGATTCTCCAAGCAGTGAGAAGTCACCTGTTATGACACC
TTTTAAGTTCTGGGCATGGGACCCAGAAGAGGAGCGCAGGCGACAGGAAAAATGGCAACAGGAACAGGAACGTTTGCTCCAGGAGAGATA
CCAGAAGGAGCAGGACAAGCTGAAAGAAGAGTGGGAAAAGGCCCAAAAGGAGGTGGAAGAGGAAGAACGCAGATACTATGAGGAGGAGCG
TAAGATAATTGAAGACACTGTGGTTCCATTTACTGTTTCTTCAAGTTCCGCTGACCAGCTGTCTACCTCTTCCTCCATGACTGAAGGCAG
TGGGACAATGAATAAGATAGACCTGGGAAACTGTCAAGATGAAAAACAAGACAGAAGATGGAAGAAATCATTCCAGGGAGATGACAGTGA
CTTATTGCTGAAGACTAGGGAAAGTGATCGACTGGAGGAGAAGGGCAGCCTAACTGAAGGGGCCTTGGCTCATTCTGGGAACCCTGTATC
AAAAGGAGTCCATGAAGACCATCAGCTGGATACCGAGGCTGGGGCCCCACACTGTGGAACAAACCCACAGCTTGCTCAGGATCCATCCCA
GAATCAGCAGACATCAAATCCAACGCACAGTTCAGAAGATGTGAAGCCAAAAACCCTCCCGCTGGATAAAAGCATTAACCATCAGATCGA
GTCTCCCAGTGAAAGGCGGAAGTCTATAAGTGGAAAGAAGCTGTGCTCTTCCTGTGGGCTTCCTTTGGGTAAAGGAGCTGCAATGATCAT
CGAGACCCTCAATCTCTATTTTCACATCCAGTGTTTCAGGTGTGGAATTTGTAAAGGCCAGCTTGGAGATGCAGTGAGTGGGACGGATGT
TAGGATTCGAAATGGTCTCCTGAACTGTAATGATTGCTACATGCGATCCAGAAGTGCCGGGCAGCCTACAACATTGTGACACGGCTTTCA
AGCTTCCGGATCACTCACCATTTCTTTACTGAGAGTGTCCCCTGGCAACTGCTTAACAAAATCCCAAGCTCAGGGGCTTCTCAGCATTTA
CCTAATTTCTGAAAGGCTCTTCTGAAAGGTGGTATCTGTTCTTTCGTAGCACAGTGTTTATGTTTTTCCTGTTTATTGTTTTGGTTTTTT
TTTTTTTTTTGCATTTGCACAGTATACACAAAAGAATATGGGGTTGTAATGATCCTGAATAGCTCAAAAAAGGTTTTAGCATGGTCAAAC
AGGCTTATGGTTTAAAATGTGTTATTCTCTTCTTTGGGAATTAGCTAAATGATGCAATAAACCTGTTTTGTTTTAGAATGTCTAGGAATT
AAACACTTTATGTTTACAGAATTGAGCTGCAGAAAGTGCAAGACATGCCAATTTGAGACACACGGTCTTCTAAGACTGAAGGATAAATTT
AATGCATTTCAGAAACTAAACATCACAGCAAGCTCTATCTCTGAGCTATAATTTGTTTTTAATGCAAAGACACTAGTTTGATAATATATA
CTGTAATCCTGAAACATTTGTGTTACTTACCTTTGGAGGTAGAAATTATACCAATAAATTATTGCACCGTTAGTATTAGATTCTGTGTAC
CTTGGAAGTTATGTCATTAATATAGGCTGGTTCATCAAATAAAGCAAAACCTTGCAATATCAGCTAGATTTACACTCCGGGACGTTGCCC
AAAGGTAGGAAGAAAGCAGAGGGAAATATTTCAGTCATCATTTCCAAAGTCATTATCAAAATCTGTGAGGAAGTTTAATCTTCCAAAGAG
TCAATGTCAGACATCAGGCCTCTGTTGCCTGCTTCTCTCGAGGCACTAGATTAGGAGTCTTCAATAAGAGACTTAACATGAGGTATATGG
AAGATGAGGCACCGAGATAAGTTCATCATTAGGTGTGAGCACTGCTCACCCTTGCTGGCAAGTTCTCCTTAAGGGCCTGAAGCACAGGTG
TCCAAAGAAAAGCGTTAAGTCCATCTTAATAGAATCTATGTGGTATATGATGTGGTCAGCCCCTGGTCTGTGATCAGCAAGAACCTACAG
CACAGATTATGCCCTGCCCACTTCAATGAATACCTACTCTCCTCCATTCTCCATCACTTTTTTTGCTATCAAGAACTCCGGACCTTGCCC
ATGGAGAAGTTTAGAGAGGAACTCTTGTGGAGAGCTGGTTTATTTTCTGCCCTGTGCGACGAGTTTCAGCTGGCCAAGAAAGGAGTCAAG
TTATTAAAAAGCATCACAATGTAGATCTCCAGGCTGGTTTTTTGTTTTTTGTTGTTAAGACTGGGGAAAGGGGGACTATTTATTCTGCCT
TAAATCAATGGCAAATAAGTCAAGATGACATTTTGTGAATGTAGACTATGGATACACTCCTAATAGATTGATGTAGTCATAAAAGGGGGT
CAAGTAGATGTTTTTCTGTTATGTAAGCAATAATTTTTCCGTGTCTTATTGAGTATGGCTAGCGATTATTTATTACATGCTAGATGGGTT
CTTTGCATGTGGGTTCCATATAGGTGCAGAAATTTCCTCAGCCACTGGAGGGATTTCGACCATATTTGTCATTTGGATGAGCTGTTATTA
GATTGAAATCTACACATCATTTCATTAAAAATTGTGCCTTAGAAAACGCAAAGCTGTTGCACATGGCGATAAATTATGGATGCAGTACAT
TGAAGAGAGATGAAGTCACTTCCAAGTTTCCAAGACTTCTCATGGAGGTGTTTGCTGTTTTACAGGAAAAAATAAAAATAAAAAAAGAAA

>42322_42322_2_KIAA1328-LIMCH1_KIAA1328_chr18_34539398_ENST00000543923_LIMCH1_chr4_41663437_ENST00000513024_length(amino acids)=538AA_BP=83
MNRVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELGAARMQEQQATTEKT
EPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVLSQKVVKPKSPEPEA
TLTFPFLDKMPEANQLHLPNLNSQESPGTASVPLRVQNSWRRSQFFSQSVDSPSSEKSPVMTPFKFWAWDPEEERRRQEKWQQEQERLLQ
ERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQDEKQDRRWKKSFQGD
DSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINH

--------------------------------------------------------------
>42322_42322_3_KIAA1328-LIMCH1_KIAA1328_chr18_34539398_ENST00000591619_LIMCH1_chr4_41663437_ENST00000513024_length(transcript)=4533nt_BP=1350nt
TTAAATCAATACCAATTTTATTCTTTCATAGATGGAGCCAGACATTCTTTTATGTTTGAGGGTACAACACTGAACAAAATAAAACAAAAA
TCATTACCCTCTTGGTGCCTACATTTTAGTGAGATGAGATCAGGTCATGAATAAGGAAAATATATGTTCAATGATTTTTTTTTTTTTTTT
TGAGTCAGAGTCTCGGTCTGTTGCCCAGGCTGGAGTGCAGTGGTGCCATCTCAGCTCACTGCAAGCTCCGCCTTCTGGGTTCACACCATT
CTCCTGCCTCAACCTCTGGAGTAGCTGGGACTACAGGCACCCGCCACCATGCCCGGCTAATTTTTTTTTTTTACATTTTTAGTAGAGACA
GGGTTTCACCGTGTTAGCCAGGATGATCTCGATTTTCTGACCTCGTGATATGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGACGT
GAGCCACTGCACCTGGCCTATGTTCAATGATATTGGTGCTGTGGAGAAAAAATAAAGCAGGAAAGAGGCAGATAGTAGCGGGAGGTAGGT
AGGTTGTGGGAAGAGAGAGTTTTGCAATTTCAAGTACCTATATGGTTAGGAAGTGAAAGCTTCAATCAGAAGGTGACATGACATGACATA
TGACATAAGTCCTAAAGTGAGCCATGAAGATATTTGAGGAAAGAGCTTCCTGGGTAGAAGAAATCATACCTGCAGAAGCTATAAGTTAGT
TACAAATTCCCAGGTCAAAAGAAATTATGAATTATAAGAGGTATACAGAACAGAAGCAGCATTTGGATGCCGGATAATATTATTGTATTT
TCCTTCATGTTCTCCTGCGTAGTTTCTGATGAAGAACAATCAGTAGTATACGTTCCAGGAATTTCTGCTGAAGGAAATGTCAGATCAAGA
CACAAGCTGATGAGTCCAAAAGCTGATGTTAAACTTAAGACTTCCAGGGTGACTGATGCTTCAATCTCCATGGAGTCCTTAAAAGGCACA
GGAGATTCAGTAGATGAACAGAATTCCTGCAGGGGAGAAATAAAGAGTGCATCATTGAAGGATTTATGTCTTGAAGACAAAAGACGCATT
GCAAACTTAATTAAAGAACTGGCCAGAGTAAGTGAGGAAAAGGAAGTGACAGAGGAAAGACTGAAAGCTGAGCAGGAGTCATTTGAGAAG
AAGATCAGGCAGTTGGAAGAACAGAATGAACTGATCATCAAAGAAAGGGAAGCTCTTCAGCTACAGTATAGAGAATGCCAAGAACTTCTA
AGCCTGTATCAGAAATATTTATCAGAACAACAGGAGAAGCTCACCATGTCTCTCTCAGAACTTGGTGCTGCTAGAATGCAGGAACAGCAG
GCAACCACTGAGAAAACGGAACCGAATAGTCAAGAGGACAAGAATGATGGTGGAAAATCAAGAAAAGGGAATATAGAACTTGCCTCATCA
GAACCACAGCATTTTACAACAACTGTGACTCGATGCAGCCCGACCGTGGCCTTTGTGGAATTTCCCTCCAGCCCCCAGCTGAAGAATGAT
GTGTCGGAAGAAAAAGACCAGAAGAAACCAGAAAATGAAATGAGTGGAAAGGTGGAGTTGGTGCTGTCACAAAAGGTGGTAAAGCCAAAA
TCTCCAGAACCCGAAGCAACGCTGACATTTCCATTTCTGGACAAAATGCCTGAAGCCAACCAACTACATTTGCCAAATCTCAATTCTCAA
GAGTCGCCTGGCACTGCCAGTGTTCCGCTTAGAGTTCAGAACTCTTGGCGACGATCCCAGTTTTTCTCCCAGTCAGTGGATTCTCCAAGC
AGTGAGAAGTCACCTGTTATGACACCTTTTAAGTTCTGGGCATGGGACCCAGAAGAGGAGCGCAGGCGACAGGAAAAATGGCAACAGGAA
CAGGAACGTTTGCTCCAGGAGAGATACCAGAAGGAGCAGGACAAGCTGAAAGAAGAGTGGGAAAAGGCCCAAAAGGAGGTGGAAGAGGAA
GAACGCAGATACTATGAGGAGGAGCGTAAGATAATTGAAGACACTGTGGTTCCATTTACTGTTTCTTCAAGTTCCGCTGACCAGCTGTCT
ACCTCTTCCTCCATGACTGAAGGCAGTGGGACAATGAATAAGATAGACCTGGGAAACTGTCAAGATGAAAAACAAGACAGAAGATGGAAG
AAATCATTCCAGGGAGATGACAGTGACTTATTGCTGAAGACTAGGGAAAGTGATCGACTGGAGGAGAAGGGCAGCCTAACTGAAGGGGCC
TTGGCTCATTCTGGGAACCCTGTATCAAAAGGAGTCCATGAAGACCATCAGCTGGATACCGAGGCTGGGGCCCCACACTGTGGAACAAAC
CCACAGCTTGCTCAGGATCCATCCCAGAATCAGCAGACATCAAATCCAACGCACAGTTCAGAAGATGTGAAGCCAAAAACCCTCCCGCTG
GATAAAAGCATTAACCATCAGATCGAGTCTCCCAGTGAAAGGCGGAAGTCTATAAGTGGAAAGAAGCTGTGCTCTTCCTGTGGGCTTCCT
TTGGGTAAAGGAGCTGCAATGATCATCGAGACCCTCAATCTCTATTTTCACATCCAGTGTTTCAGGTGTGGAATTTGTAAAGGCCAGCTT
GGAGATGCAGTGAGTGGGACGGATGTTAGGATTCGAAATGGTCTCCTGAACTGTAATGATTGCTACATGCGATCCAGAAGTGCCGGGCAG
CCTACAACATTGTGACACGGCTTTCAAGCTTCCGGATCACTCACCATTTCTTTACTGAGAGTGTCCCCTGGCAACTGCTTAACAAAATCC
CAAGCTCAGGGGCTTCTCAGCATTTACCTAATTTCTGAAAGGCTCTTCTGAAAGGTGGTATCTGTTCTTTCGTAGCACAGTGTTTATGTT
TTTCCTGTTTATTGTTTTGGTTTTTTTTTTTTTTTTGCATTTGCACAGTATACACAAAAGAATATGGGGTTGTAATGATCCTGAATAGCT
CAAAAAAGGTTTTAGCATGGTCAAACAGGCTTATGGTTTAAAATGTGTTATTCTCTTCTTTGGGAATTAGCTAAATGATGCAATAAACCT
GTTTTGTTTTAGAATGTCTAGGAATTAAACACTTTATGTTTACAGAATTGAGCTGCAGAAAGTGCAAGACATGCCAATTTGAGACACACG
GTCTTCTAAGACTGAAGGATAAATTTAATGCATTTCAGAAACTAAACATCACAGCAAGCTCTATCTCTGAGCTATAATTTGTTTTTAATG
CAAAGACACTAGTTTGATAATATATACTGTAATCCTGAAACATTTGTGTTACTTACCTTTGGAGGTAGAAATTATACCAATAAATTATTG
CACCGTTAGTATTAGATTCTGTGTACCTTGGAAGTTATGTCATTAATATAGGCTGGTTCATCAAATAAAGCAAAACCTTGCAATATCAGC
TAGATTTACACTCCGGGACGTTGCCCAAAGGTAGGAAGAAAGCAGAGGGAAATATTTCAGTCATCATTTCCAAAGTCATTATCAAAATCT
GTGAGGAAGTTTAATCTTCCAAAGAGTCAATGTCAGACATCAGGCCTCTGTTGCCTGCTTCTCTCGAGGCACTAGATTAGGAGTCTTCAA
TAAGAGACTTAACATGAGGTATATGGAAGATGAGGCACCGAGATAAGTTCATCATTAGGTGTGAGCACTGCTCACCCTTGCTGGCAAGTT
CTCCTTAAGGGCCTGAAGCACAGGTGTCCAAAGAAAAGCGTTAAGTCCATCTTAATAGAATCTATGTGGTATATGATGTGGTCAGCCCCT
GGTCTGTGATCAGCAAGAACCTACAGCACAGATTATGCCCTGCCCACTTCAATGAATACCTACTCTCCTCCATTCTCCATCACTTTTTTT
GCTATCAAGAACTCCGGACCTTGCCCATGGAGAAGTTTAGAGAGGAACTCTTGTGGAGAGCTGGTTTATTTTCTGCCCTGTGCGACGAGT
TTCAGCTGGCCAAGAAAGGAGTCAAGTTATTAAAAAGCATCACAATGTAGATCTCCAGGCTGGTTTTTTGTTTTTTGTTGTTAAGACTGG
GGAAAGGGGGACTATTTATTCTGCCTTAAATCAATGGCAAATAAGTCAAGATGACATTTTGTGAATGTAGACTATGGATACACTCCTAAT
AGATTGATGTAGTCATAAAAGGGGGTCAAGTAGATGTTTTTCTGTTATGTAAGCAATAATTTTTCCGTGTCTTATTGAGTATGGCTAGCG
ATTATTTATTACATGCTAGATGGGTTCTTTGCATGTGGGTTCCATATAGGTGCAGAAATTTCCTCAGCCACTGGAGGGATTTCGACCATA
TTTGTCATTTGGATGAGCTGTTATTAGATTGAAATCTACACATCATTTCATTAAAAATTGTGCCTTAGAAAACGCAAAGCTGTTGCACAT
GGCGATAAATTATGGATGCAGTACATTGAAGAGAGATGAAGTCACTTCCAAGTTTCCAAGACTTCTCATGGAGGTGTTTGCTGTTTTACA

>42322_42322_3_KIAA1328-LIMCH1_KIAA1328_chr18_34539398_ENST00000591619_LIMCH1_chr4_41663437_ENST00000513024_length(amino acids)=642AA_BP=187
MPDNIIVFSFMFSCVVSDEEQSVVYVPGISAEGNVRSRHKLMSPKADVKLKTSRVTDASISMESLKGTGDSVDEQNSCRGEIKSASLKDL
CLEDKRRIANLIKELARVSEEKEVTEERLKAEQESFEKKIRQLEEQNELIIKEREALQLQYRECQELLSLYQKYLSEQQEKLTMSLSELG
AARMQEQQATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQLKNDVSEEKDQKKPENEMSGKVELVL
SQKVVKPKSPEPEATLTFPFLDKMPEANQLHLPNLNSQESPGTASVPLRVQNSWRRSQFFSQSVDSPSSEKSPVMTPFKFWAWDPEEERR
RQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTVSSSSADQLSTSSSMTEGSGTMNKIDLGNCQD
EKQDRRWKKSFQGDDSDLLLKTRESDRLEEKGSLTEGALAHSGNPVSKGVHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSED
VKPKTLPLDKSINHQIESPSERRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCY

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Fusion Gene PPI Analysis for KIAA1328-LIMCH1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KIAA1328-LIMCH1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KIAA1328-LIMCH1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource