FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:KIAA1432-AARD (FusionGDB2 ID:42341)

Fusion Gene Summary for KIAA1432-AARD

check button Fusion gene summary
Fusion gene informationFusion gene name: KIAA1432-AARD
Fusion gene ID: 42341
HgeneTgene
Gene symbol

KIAA1432

AARD

Gene ID

57589

441376

Gene nameRIC1 homolog, RAB6A GEF complex partner 1alanine and arginine rich domain containing protein
SynonymsCATIFA|CIP150|KIAA1432|bA207C16.1C8orf85
Cytomap

9p24.1

8q24.11

Type of geneprotein-codingprotein-coding
DescriptionRAB6A-GEF complex partner protein 1RAB6A GEF complex partner 1connexin 43-interacting protein 150 kDaconnexin-43-interacting protein of 150 kDaprotein RIC1 homologalanine and arginine-rich domain-containing protein
Modification date2020031320200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000251879, ENST00000381532, 
ENST00000414202, ENST00000418622, 
ENST00000449720, 		ENST00000523536, 
ENST00000378279, 
Fusion gene scores* DoF score12 X 6 X 9=6483 X 2 X 3=18
# samples 144
** MAII scorelog2(14/648*10)=-2.21056698593966
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/18*10)=1.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: KIAA1432 [Title/Abstract] AND AARD [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKIAA1432(5690038)-AARD(117954796), # samples:1
KIAA1432(5690038)-AARD(117954797), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKIAA1432

GO:0043547

positive regulation of GTPase activity

23091056


check buttonFusion gene breakpoints across KIAA1432 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across AARD (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-75-6207-01AKIAA1432chr9

5690038

+AARDchr8

117954797

+
ChimerDB4LUADTCGA-75-6207KIAA1432chr9

5690038

+AARDchr8

117954796

+


Top

Fusion Gene ORF analysis for KIAA1432-AARD

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000251879ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954797

+
5CDS-3UTRENST00000251879ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954796

+
5CDS-3UTRENST00000381532ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954797

+
5CDS-3UTRENST00000381532ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954796

+
5CDS-3UTRENST00000414202ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954797

+
5CDS-3UTRENST00000414202ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954796

+
5CDS-3UTRENST00000418622ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954797

+
5CDS-3UTRENST00000418622ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954796

+
5CDS-3UTRENST00000449720ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954797

+
5CDS-3UTRENST00000449720ENST00000523536KIAA1432chr9

5690038

+AARDchr8

117954796

+
In-frameENST00000251879ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954797

+
In-frameENST00000251879ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954796

+
In-frameENST00000381532ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954797

+
In-frameENST00000381532ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954796

+
In-frameENST00000414202ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954797

+
In-frameENST00000414202ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954796

+
In-frameENST00000418622ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954797

+
In-frameENST00000418622ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954796

+
In-frameENST00000449720ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954797

+
In-frameENST00000449720ENST00000378279KIAA1432chr9

5690038

+AARDchr8

117954796

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000251879KIAA1432chr95690038+ENST00000378279AARDchr8117954796+254761748668206
ENST00000414202KIAA1432chr95690038+ENST00000378279AARDchr8117954796+2453523143574143
ENST00000381532KIAA1432chr95690038+ENST00000378279AARDchr8117954796+224531513366117
ENST00000418622KIAA1432chr95690038+ENST00000378279AARDchr8117954796+2118188826521101
ENST00000449720KIAA1432chr95690038+ENST00000378279AARDchr8117954796+2047117755450101
ENST00000251879KIAA1432chr95690038+ENST00000378279AARDchr8117954797+254761748668206
ENST00000414202KIAA1432chr95690038+ENST00000378279AARDchr8117954797+2453523143574143
ENST00000381532KIAA1432chr95690038+ENST00000378279AARDchr8117954797+224531513366117
ENST00000418622KIAA1432chr95690038+ENST00000378279AARDchr8117954797+2118188826521101
ENST00000449720KIAA1432chr95690038+ENST00000378279AARDchr8117954797+2047117755450101

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000251879ENST00000378279KIAA1432chr95690038+AARDchr8117954796+0.49245240.50754756
ENST00000414202ENST00000378279KIAA1432chr95690038+AARDchr8117954796+0.312861740.6871382
ENST00000381532ENST00000378279KIAA1432chr95690038+AARDchr8117954796+0.728200550.27179945
ENST00000418622ENST00000378279KIAA1432chr95690038+AARDchr8117954796+0.922614630.0773853
ENST00000449720ENST00000378279KIAA1432chr95690038+AARDchr8117954796+0.849719350.15028067
ENST00000251879ENST00000378279KIAA1432chr95690038+AARDchr8117954797+0.49245240.50754756
ENST00000414202ENST00000378279KIAA1432chr95690038+AARDchr8117954797+0.312861740.6871382
ENST00000381532ENST00000378279KIAA1432chr95690038+AARDchr8117954797+0.728200550.27179945
ENST00000418622ENST00000378279KIAA1432chr95690038+AARDchr8117954797+0.922614630.0773853
ENST00000449720ENST00000378279KIAA1432chr95690038+AARDchr8117954797+0.849719350.15028067

Top

Fusion Genomic Features for KIAA1432-AARD


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KIAA1432chr95690038+AARDchr8117954796+2.86E-060.99999714
KIAA1432chr95690038+AARDchr8117954796+2.86E-060.99999714
KIAA1432chr95690038+AARDchr8117954796+2.86E-060.99999714
KIAA1432chr95690038+AARDchr8117954796+2.86E-060.99999714

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for KIAA1432-AARD


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:5690038/chr8:117954796)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000251879+32264_1031101166.0RepeatNote=WD 1
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000414202+32664_1031101424.0RepeatNote=WD 1
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000251879+32264_1031101166.0RepeatNote=WD 1
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000414202+32664_1031101424.0RepeatNote=WD 1

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000251879+322304_3431101166.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000381532+322304_343311087.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000381532+32264_103311087.0RepeatNote=WD 1
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000414202+326304_3431101424.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000418622+225304_343311345.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000418622+22564_103311345.0RepeatNote=WD 1
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000449720+224304_343311308.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954796ENST00000449720+22464_103311308.0RepeatNote=WD 1
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000251879+322304_3431101166.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000381532+322304_343311087.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000381532+32264_103311087.0RepeatNote=WD 1
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000414202+326304_3431101424.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000418622+225304_343311345.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000418622+22564_103311345.0RepeatNote=WD 1
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000449720+224304_343311308.0RepeatNote=WD 2
HgeneKIAA1432chr9:5690038chr8:117954797ENST00000449720+22464_103311308.0RepeatNote=WD 1
TgeneAARDchr9:5690038chr8:117954796ENST000003782790260_105108156.0Compositional biasNote=Ala/Arg-rich
TgeneAARDchr9:5690038chr8:117954797ENST000003782790260_105108156.0Compositional biasNote=Ala/Arg-rich


Top

Fusion Gene Sequence for KIAA1432-AARD


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42341_42341_1_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000251879_AARD_chr8_117954796_ENST00000378279_length(transcript)=2547nt_BP=617nt
GAGGAAGGGGCGGGGTCGGGGCGGGCCTCCGCGCTCCTCCCGCCCTCTCTGTGTCCCTACTCTCCCTCCCCTTCCCTCCCCCACACTCGG
CCCCGTCAGCTTGGGGGTGCCTTCGTCGCGCAGCCTTGCGTCGGCCCGGCCCGGCCAGGCCAGCGGGCAGATGCCCCGAGCTGCCGCCGC
CGCCGCCGCCGACTCGGCCGGTGGCGGTGTGGGAGGTGGGCGACCAGCCCGGGGCCGCTGAGTGTGACGGACGCAACTGGGGGCGCCGGG
GGCTCCGCACGGACCATGTATTTTCTGAGCGGCTGGCCCAAGAGGCTGCTGTGCCCTCTGGGGAGCCCGGCCGAGGCGCCTTTCCACGTT
CAGTCCGACCCGCAGAGGGCTTTCTTCGCCGTGCTGGCCGCGGCCCGCCTCAGCATCTGGTACAGCCGACCTAGTGTGTTAATTGTAACC
TACAAGGAGCCTGCAAAATCATCTACTCAGTTTGGATCCTACAAGCAAGCTGAATGGAGGCCAGATAGTACCATGATAGCTGTATCAACG
GCAAATGGATACATCTTGTTTTTTCATATTACATCTACAAGAGGGGACAAGTACCTTTATGAACCAGTGTATCCCAAGTGGAAATGCATT
TCCAAAACCACCAGCTGGCTAGAACTTTACTGGACCTAAACATGAAAGTGCAGCAATTGAAAAAGGAGTATGAACTGGAAATTACATCAG
ACTCCCAAAGCCCAAAAGATGATGCTGCGAATCCGGAATAAAGAAATGCACACGCAAGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCC
AGCACTTTGGGAGGCCGAGGCGGGCGGATCAAGACGTCAGGAGATTGAGACCATCCTGGCTAACACTGTGAAACCCTGCCTCTACTAAAA
ATACAAAAAATTAGCCAGACGTGGTGGCAGGCACCTGTAGTCCCTGCTACTCAGGAGTCTGAGGCAGGAGAATGGCGTGAACCCAGGAGA
CAGAGCTTGCAGTGAGCCGAAATCCTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAA
AGCACACGCGAAGCTCTGGATCCTAAAACTAACGCATACAACCCTGAAACAATTCTGATGAACACATTATGCTTTGCATAAGTTTTGAGG
GGCAATTTATAGACCCAAAACAAATGACAGGGGAAGGTGACAGAAAAACATCTAAGAGAGGGGAGAGAAAAATGATGTATTACCAAGTTT
TAAAGTTATTTATTTGTTATTTTTACTGGGACATAGAAGTAAAATATAACTATAGATAAATCTCTCTCTGTCTCTCTCACTCAAAGAATG
CTTTAATGCCAACTTTCGGTATTCAACCTTGTGTCACCTGACCTTTCTGGCATTGCCTGAGCTTTCAGAGTTTGTGCTTGTTTTGTTTTA
CTTGATTATTCTCAGTTTGTCTGTCCAGCAGCCTGCCCTGCTTCTTGTGGAGAATTGTTTCTACTTGGATTCTAACCATGCCCTTTAGGT
GGTCTGTGACTAAGGGTATTCCATCTTCCTGGATATAGTCATGCAGCTCAAGGCAGGCAGATGGGTTTGTCCTTAGGATTTTTGAATGGG
CACTAAAAGAGTAGATGACTATTTCTGCCAGTAGAAGCTGTGGATCAGGGGCTTGGAAGCTGCTGGTGGTCACCATGTGAGAAAGCCCAC
ACCCTAATGGAGGTGACTGAAACGGAACCACTAAAAGCACAAAAGGGGAGGGAGGGAGGGAGGGTGCTTCGCTTCCTTGTTCCTGGGGTC
AAGCTGTATAAGACTCCAGGCCTTGCTCTTGTTTATGTACATGAAATATTCTGATATCCTTCTCATAAAATCTCTTTTTGCCTAAGTAAA
TTCAAGCTGGAGTTTCATGACTTGTATCTAGTGTTCATAACTAATACAGTTGTTCAGTTTTAGGAGTTAAAATGGTTCTTACTGTTGAAT
TGGACTATCTAACTGTACCCGAAAAGTGCTGTCTTTTTAATGCAAACAGTAAAGTTAATAAAAAATAGTTGCAGATCTAAGTGATATTTA
TAATGGTTATTGTCTGCAAAATACAAATTAATTTATAACAAGCTATGTAATTTTAATATTTAATAAACTATAAAAATCAGTTCTTGAAGA
CAAAGGAGAACAGAAGAGACACAGTCTTTCTCTTGTTAAAAGAAATACAAGGACAAGCATGGTGGATCACGCTTGTAATTCCAGCACTTT
GGGAGGCTGAGGTGGGCAGATTGTTTGAGCTCAGGAGTTTGAGACCAGCCTGGTCAACATGGCAAAACCCCATCTCTACTAAAAATACAA
AAATTAGCCAGGCGTGGTGGTGCTCGCCTATAGTACCAGCTACTCAGGAGGCTGAGGCATAAGAATCACTTGAACCTGGGAGATGGAGGT
TGCAGTGAGCCGAGATCATGCCCCTGCACTCCAGCCTGGGTGACAGAGGGGGACTTGGCCTCGAAAAAATAAATAAATAATAAAAATAAA

>42341_42341_1_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000251879_AARD_chr8_117954796_ENST00000378279_length(amino acids)=206AA_BP=190
MCPYSPSPSLPHTRPRQLGGAFVAQPCVGPARPGQRADAPSCRRRRRRLGRWRCGRWATSPGPLSVTDATGGAGGSARTMYFLSGWPKRL
LCPLGSPAEAPFHVQSDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSTRGD

--------------------------------------------------------------
>42341_42341_2_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000251879_AARD_chr8_117954797_ENST00000378279_length(transcript)=2547nt_BP=617nt
GAGGAAGGGGCGGGGTCGGGGCGGGCCTCCGCGCTCCTCCCGCCCTCTCTGTGTCCCTACTCTCCCTCCCCTTCCCTCCCCCACACTCGG
CCCCGTCAGCTTGGGGGTGCCTTCGTCGCGCAGCCTTGCGTCGGCCCGGCCCGGCCAGGCCAGCGGGCAGATGCCCCGAGCTGCCGCCGC
CGCCGCCGCCGACTCGGCCGGTGGCGGTGTGGGAGGTGGGCGACCAGCCCGGGGCCGCTGAGTGTGACGGACGCAACTGGGGGCGCCGGG
GGCTCCGCACGGACCATGTATTTTCTGAGCGGCTGGCCCAAGAGGCTGCTGTGCCCTCTGGGGAGCCCGGCCGAGGCGCCTTTCCACGTT
CAGTCCGACCCGCAGAGGGCTTTCTTCGCCGTGCTGGCCGCGGCCCGCCTCAGCATCTGGTACAGCCGACCTAGTGTGTTAATTGTAACC
TACAAGGAGCCTGCAAAATCATCTACTCAGTTTGGATCCTACAAGCAAGCTGAATGGAGGCCAGATAGTACCATGATAGCTGTATCAACG
GCAAATGGATACATCTTGTTTTTTCATATTACATCTACAAGAGGGGACAAGTACCTTTATGAACCAGTGTATCCCAAGTGGAAATGCATT
TCCAAAACCACCAGCTGGCTAGAACTTTACTGGACCTAAACATGAAAGTGCAGCAATTGAAAAAGGAGTATGAACTGGAAATTACATCAG
ACTCCCAAAGCCCAAAAGATGATGCTGCGAATCCGGAATAAAGAAATGCACACGCAAGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCC
AGCACTTTGGGAGGCCGAGGCGGGCGGATCAAGACGTCAGGAGATTGAGACCATCCTGGCTAACACTGTGAAACCCTGCCTCTACTAAAA
ATACAAAAAATTAGCCAGACGTGGTGGCAGGCACCTGTAGTCCCTGCTACTCAGGAGTCTGAGGCAGGAGAATGGCGTGAACCCAGGAGA
CAGAGCTTGCAGTGAGCCGAAATCCTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAA
AGCACACGCGAAGCTCTGGATCCTAAAACTAACGCATACAACCCTGAAACAATTCTGATGAACACATTATGCTTTGCATAAGTTTTGAGG
GGCAATTTATAGACCCAAAACAAATGACAGGGGAAGGTGACAGAAAAACATCTAAGAGAGGGGAGAGAAAAATGATGTATTACCAAGTTT
TAAAGTTATTTATTTGTTATTTTTACTGGGACATAGAAGTAAAATATAACTATAGATAAATCTCTCTCTGTCTCTCTCACTCAAAGAATG
CTTTAATGCCAACTTTCGGTATTCAACCTTGTGTCACCTGACCTTTCTGGCATTGCCTGAGCTTTCAGAGTTTGTGCTTGTTTTGTTTTA
CTTGATTATTCTCAGTTTGTCTGTCCAGCAGCCTGCCCTGCTTCTTGTGGAGAATTGTTTCTACTTGGATTCTAACCATGCCCTTTAGGT
GGTCTGTGACTAAGGGTATTCCATCTTCCTGGATATAGTCATGCAGCTCAAGGCAGGCAGATGGGTTTGTCCTTAGGATTTTTGAATGGG
CACTAAAAGAGTAGATGACTATTTCTGCCAGTAGAAGCTGTGGATCAGGGGCTTGGAAGCTGCTGGTGGTCACCATGTGAGAAAGCCCAC
ACCCTAATGGAGGTGACTGAAACGGAACCACTAAAAGCACAAAAGGGGAGGGAGGGAGGGAGGGTGCTTCGCTTCCTTGTTCCTGGGGTC
AAGCTGTATAAGACTCCAGGCCTTGCTCTTGTTTATGTACATGAAATATTCTGATATCCTTCTCATAAAATCTCTTTTTGCCTAAGTAAA
TTCAAGCTGGAGTTTCATGACTTGTATCTAGTGTTCATAACTAATACAGTTGTTCAGTTTTAGGAGTTAAAATGGTTCTTACTGTTGAAT
TGGACTATCTAACTGTACCCGAAAAGTGCTGTCTTTTTAATGCAAACAGTAAAGTTAATAAAAAATAGTTGCAGATCTAAGTGATATTTA
TAATGGTTATTGTCTGCAAAATACAAATTAATTTATAACAAGCTATGTAATTTTAATATTTAATAAACTATAAAAATCAGTTCTTGAAGA
CAAAGGAGAACAGAAGAGACACAGTCTTTCTCTTGTTAAAAGAAATACAAGGACAAGCATGGTGGATCACGCTTGTAATTCCAGCACTTT
GGGAGGCTGAGGTGGGCAGATTGTTTGAGCTCAGGAGTTTGAGACCAGCCTGGTCAACATGGCAAAACCCCATCTCTACTAAAAATACAA
AAATTAGCCAGGCGTGGTGGTGCTCGCCTATAGTACCAGCTACTCAGGAGGCTGAGGCATAAGAATCACTTGAACCTGGGAGATGGAGGT
TGCAGTGAGCCGAGATCATGCCCCTGCACTCCAGCCTGGGTGACAGAGGGGGACTTGGCCTCGAAAAAATAAATAAATAATAAAAATAAA

>42341_42341_2_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000251879_AARD_chr8_117954797_ENST00000378279_length(amino acids)=206AA_BP=190
MCPYSPSPSLPHTRPRQLGGAFVAQPCVGPARPGQRADAPSCRRRRRRLGRWRCGRWATSPGPLSVTDATGGAGGSARTMYFLSGWPKRL
LCPLGSPAEAPFHVQSDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSTRGD

--------------------------------------------------------------
>42341_42341_3_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000381532_AARD_chr8_117954796_ENST00000378279_length(transcript)=2245nt_BP=315nt
CTGGCCCAAGAGGCTGCTGTGCCCTCTGGGGAGCCCGGCCGAGGCGCCTTTCCACGTTCAGTCCGACCCGCAGAGGGCTTTCTTCGCCGT
GCTGGCCGCGGCCCGCCTCAGCATCTGGTACAGCCGACCTAGTGTGTTAATTGTAACCTACAAGGAGCCTGCAAAATCATCTACTCAGTT
TGGATCCTACAAGCAAGCTGAATGGAGGCCAGATAGTACCATGATAGCTGTATCAACGGCAAATGGATACATCTTGTTTTTTCATATTAC
ATCTACAAGAGGGGACAAGTACCTTTATGAACCAGTGTATCCCAAGTGGAAATGCATTTCCAAAACCACCAGCTGGCTAGAACTTTACTG
GACCTAAACATGAAAGTGCAGCAATTGAAAAAGGAGTATGAACTGGAAATTACATCAGACTCCCAAAGCCCAAAAGATGATGCTGCGAAT
CCGGAATAAAGAAATGCACACGCAAGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCAA
GACGTCAGGAGATTGAGACCATCCTGGCTAACACTGTGAAACCCTGCCTCTACTAAAAATACAAAAAATTAGCCAGACGTGGTGGCAGGC
ACCTGTAGTCCCTGCTACTCAGGAGTCTGAGGCAGGAGAATGGCGTGAACCCAGGAGACAGAGCTTGCAGTGAGCCGAAATCCTGCCACT
GCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAGCACACGCGAAGCTCTGGATCCTAAAACTAA
CGCATACAACCCTGAAACAATTCTGATGAACACATTATGCTTTGCATAAGTTTTGAGGGGCAATTTATAGACCCAAAACAAATGACAGGG
GAAGGTGACAGAAAAACATCTAAGAGAGGGGAGAGAAAAATGATGTATTACCAAGTTTTAAAGTTATTTATTTGTTATTTTTACTGGGAC
ATAGAAGTAAAATATAACTATAGATAAATCTCTCTCTGTCTCTCTCACTCAAAGAATGCTTTAATGCCAACTTTCGGTATTCAACCTTGT
GTCACCTGACCTTTCTGGCATTGCCTGAGCTTTCAGAGTTTGTGCTTGTTTTGTTTTACTTGATTATTCTCAGTTTGTCTGTCCAGCAGC
CTGCCCTGCTTCTTGTGGAGAATTGTTTCTACTTGGATTCTAACCATGCCCTTTAGGTGGTCTGTGACTAAGGGTATTCCATCTTCCTGG
ATATAGTCATGCAGCTCAAGGCAGGCAGATGGGTTTGTCCTTAGGATTTTTGAATGGGCACTAAAAGAGTAGATGACTATTTCTGCCAGT
AGAAGCTGTGGATCAGGGGCTTGGAAGCTGCTGGTGGTCACCATGTGAGAAAGCCCACACCCTAATGGAGGTGACTGAAACGGAACCACT
AAAAGCACAAAAGGGGAGGGAGGGAGGGAGGGTGCTTCGCTTCCTTGTTCCTGGGGTCAAGCTGTATAAGACTCCAGGCCTTGCTCTTGT
TTATGTACATGAAATATTCTGATATCCTTCTCATAAAATCTCTTTTTGCCTAAGTAAATTCAAGCTGGAGTTTCATGACTTGTATCTAGT
GTTCATAACTAATACAGTTGTTCAGTTTTAGGAGTTAAAATGGTTCTTACTGTTGAATTGGACTATCTAACTGTACCCGAAAAGTGCTGT
CTTTTTAATGCAAACAGTAAAGTTAATAAAAAATAGTTGCAGATCTAAGTGATATTTATAATGGTTATTGTCTGCAAAATACAAATTAAT
TTATAACAAGCTATGTAATTTTAATATTTAATAAACTATAAAAATCAGTTCTTGAAGACAAAGGAGAACAGAAGAGACACAGTCTTTCTC
TTGTTAAAAGAAATACAAGGACAAGCATGGTGGATCACGCTTGTAATTCCAGCACTTTGGGAGGCTGAGGTGGGCAGATTGTTTGAGCTC
AGGAGTTTGAGACCAGCCTGGTCAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCTCGCCTATA
GTACCAGCTACTCAGGAGGCTGAGGCATAAGAATCACTTGAACCTGGGAGATGGAGGTTGCAGTGAGCCGAGATCATGCCCCTGCACTCC

>42341_42341_3_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000381532_AARD_chr8_117954796_ENST00000378279_length(amino acids)=117AA_BP=101
MLCPLGSPAEAPFHVQSDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSTRG

--------------------------------------------------------------
>42341_42341_4_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000381532_AARD_chr8_117954797_ENST00000378279_length(transcript)=2245nt_BP=315nt
CTGGCCCAAGAGGCTGCTGTGCCCTCTGGGGAGCCCGGCCGAGGCGCCTTTCCACGTTCAGTCCGACCCGCAGAGGGCTTTCTTCGCCGT
GCTGGCCGCGGCCCGCCTCAGCATCTGGTACAGCCGACCTAGTGTGTTAATTGTAACCTACAAGGAGCCTGCAAAATCATCTACTCAGTT
TGGATCCTACAAGCAAGCTGAATGGAGGCCAGATAGTACCATGATAGCTGTATCAACGGCAAATGGATACATCTTGTTTTTTCATATTAC
ATCTACAAGAGGGGACAAGTACCTTTATGAACCAGTGTATCCCAAGTGGAAATGCATTTCCAAAACCACCAGCTGGCTAGAACTTTACTG
GACCTAAACATGAAAGTGCAGCAATTGAAAAAGGAGTATGAACTGGAAATTACATCAGACTCCCAAAGCCCAAAAGATGATGCTGCGAAT
CCGGAATAAAGAAATGCACACGCAAGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCAA
GACGTCAGGAGATTGAGACCATCCTGGCTAACACTGTGAAACCCTGCCTCTACTAAAAATACAAAAAATTAGCCAGACGTGGTGGCAGGC
ACCTGTAGTCCCTGCTACTCAGGAGTCTGAGGCAGGAGAATGGCGTGAACCCAGGAGACAGAGCTTGCAGTGAGCCGAAATCCTGCCACT
GCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAGCACACGCGAAGCTCTGGATCCTAAAACTAA
CGCATACAACCCTGAAACAATTCTGATGAACACATTATGCTTTGCATAAGTTTTGAGGGGCAATTTATAGACCCAAAACAAATGACAGGG
GAAGGTGACAGAAAAACATCTAAGAGAGGGGAGAGAAAAATGATGTATTACCAAGTTTTAAAGTTATTTATTTGTTATTTTTACTGGGAC
ATAGAAGTAAAATATAACTATAGATAAATCTCTCTCTGTCTCTCTCACTCAAAGAATGCTTTAATGCCAACTTTCGGTATTCAACCTTGT
GTCACCTGACCTTTCTGGCATTGCCTGAGCTTTCAGAGTTTGTGCTTGTTTTGTTTTACTTGATTATTCTCAGTTTGTCTGTCCAGCAGC
CTGCCCTGCTTCTTGTGGAGAATTGTTTCTACTTGGATTCTAACCATGCCCTTTAGGTGGTCTGTGACTAAGGGTATTCCATCTTCCTGG
ATATAGTCATGCAGCTCAAGGCAGGCAGATGGGTTTGTCCTTAGGATTTTTGAATGGGCACTAAAAGAGTAGATGACTATTTCTGCCAGT
AGAAGCTGTGGATCAGGGGCTTGGAAGCTGCTGGTGGTCACCATGTGAGAAAGCCCACACCCTAATGGAGGTGACTGAAACGGAACCACT
AAAAGCACAAAAGGGGAGGGAGGGAGGGAGGGTGCTTCGCTTCCTTGTTCCTGGGGTCAAGCTGTATAAGACTCCAGGCCTTGCTCTTGT
TTATGTACATGAAATATTCTGATATCCTTCTCATAAAATCTCTTTTTGCCTAAGTAAATTCAAGCTGGAGTTTCATGACTTGTATCTAGT
GTTCATAACTAATACAGTTGTTCAGTTTTAGGAGTTAAAATGGTTCTTACTGTTGAATTGGACTATCTAACTGTACCCGAAAAGTGCTGT
CTTTTTAATGCAAACAGTAAAGTTAATAAAAAATAGTTGCAGATCTAAGTGATATTTATAATGGTTATTGTCTGCAAAATACAAATTAAT
TTATAACAAGCTATGTAATTTTAATATTTAATAAACTATAAAAATCAGTTCTTGAAGACAAAGGAGAACAGAAGAGACACAGTCTTTCTC
TTGTTAAAAGAAATACAAGGACAAGCATGGTGGATCACGCTTGTAATTCCAGCACTTTGGGAGGCTGAGGTGGGCAGATTGTTTGAGCTC
AGGAGTTTGAGACCAGCCTGGTCAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCTCGCCTATA
GTACCAGCTACTCAGGAGGCTGAGGCATAAGAATCACTTGAACCTGGGAGATGGAGGTTGCAGTGAGCCGAGATCATGCCCCTGCACTCC

>42341_42341_4_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000381532_AARD_chr8_117954797_ENST00000378279_length(amino acids)=117AA_BP=101
MLCPLGSPAEAPFHVQSDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEWRPDSTMIAVSTANGYILFFHITSTRG

--------------------------------------------------------------
>42341_42341_5_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000414202_AARD_chr8_117954796_ENST00000378279_length(transcript)=2453nt_BP=523nt
GTCAGCTTGGGGGTGCCTTCGTCGCGCAGCCTTGCGTCGGCCCGGCCCGGCCAGGCCAGCGGGCAGATGCCCCGAGCTGCCGCCGCCGCC
GCCGCCGACTCGGCCGGTGGCGGTGTGGGAGGTGGGCGACCAGCCCGGGGCCGCTGAGTGTGACGGACGCAACTGGGGGCGCCGGGGGCT
CCGCACGGACCATGTATTTTCTGAGCGGCTGGCCCAAGAGGCTGCTGTGCCCTCTGGGGAGCCCGGCCGAGGCGCCTTTCCACGTTCAGT
CCGACCCGCAGAGGGCTTTCTTCGCCGTGCTGGCCGCGGCCCGCCTCAGCATCTGGTACAGCCGACCTAGTGTGTTAATTGTAACCTACA
AGGAGCCTGCAAAATCATCTACTCAGTTTGGATCCTACAAGCAAGCTGAATGGAGGCCAGATAGTACCATGATAGCTGTATCAACGGCAA
ATGGATACATCTTGTTTTTTCATATTACATCTACAAGAGGGGACAAGTACCTTTATGAACCAGTGTATCCCAAGTGGAAATGCATTTCCA
AAACCACCAGCTGGCTAGAACTTTACTGGACCTAAACATGAAAGTGCAGCAATTGAAAAAGGAGTATGAACTGGAAATTACATCAGACTC
CCAAAGCCCAAAAGATGATGCTGCGAATCCGGAATAAAGAAATGCACACGCAAGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCA
CTTTGGGAGGCCGAGGCGGGCGGATCAAGACGTCAGGAGATTGAGACCATCCTGGCTAACACTGTGAAACCCTGCCTCTACTAAAAATAC
AAAAAATTAGCCAGACGTGGTGGCAGGCACCTGTAGTCCCTGCTACTCAGGAGTCTGAGGCAGGAGAATGGCGTGAACCCAGGAGACAGA
GCTTGCAGTGAGCCGAAATCCTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAGCA
CACGCGAAGCTCTGGATCCTAAAACTAACGCATACAACCCTGAAACAATTCTGATGAACACATTATGCTTTGCATAAGTTTTGAGGGGCA
ATTTATAGACCCAAAACAAATGACAGGGGAAGGTGACAGAAAAACATCTAAGAGAGGGGAGAGAAAAATGATGTATTACCAAGTTTTAAA
GTTATTTATTTGTTATTTTTACTGGGACATAGAAGTAAAATATAACTATAGATAAATCTCTCTCTGTCTCTCTCACTCAAAGAATGCTTT
AATGCCAACTTTCGGTATTCAACCTTGTGTCACCTGACCTTTCTGGCATTGCCTGAGCTTTCAGAGTTTGTGCTTGTTTTGTTTTACTTG
ATTATTCTCAGTTTGTCTGTCCAGCAGCCTGCCCTGCTTCTTGTGGAGAATTGTTTCTACTTGGATTCTAACCATGCCCTTTAGGTGGTC
TGTGACTAAGGGTATTCCATCTTCCTGGATATAGTCATGCAGCTCAAGGCAGGCAGATGGGTTTGTCCTTAGGATTTTTGAATGGGCACT
AAAAGAGTAGATGACTATTTCTGCCAGTAGAAGCTGTGGATCAGGGGCTTGGAAGCTGCTGGTGGTCACCATGTGAGAAAGCCCACACCC
TAATGGAGGTGACTGAAACGGAACCACTAAAAGCACAAAAGGGGAGGGAGGGAGGGAGGGTGCTTCGCTTCCTTGTTCCTGGGGTCAAGC
TGTATAAGACTCCAGGCCTTGCTCTTGTTTATGTACATGAAATATTCTGATATCCTTCTCATAAAATCTCTTTTTGCCTAAGTAAATTCA
AGCTGGAGTTTCATGACTTGTATCTAGTGTTCATAACTAATACAGTTGTTCAGTTTTAGGAGTTAAAATGGTTCTTACTGTTGAATTGGA
CTATCTAACTGTACCCGAAAAGTGCTGTCTTTTTAATGCAAACAGTAAAGTTAATAAAAAATAGTTGCAGATCTAAGTGATATTTATAAT
GGTTATTGTCTGCAAAATACAAATTAATTTATAACAAGCTATGTAATTTTAATATTTAATAAACTATAAAAATCAGTTCTTGAAGACAAA
GGAGAACAGAAGAGACACAGTCTTTCTCTTGTTAAAAGAAATACAAGGACAAGCATGGTGGATCACGCTTGTAATTCCAGCACTTTGGGA
GGCTGAGGTGGGCAGATTGTTTGAGCTCAGGAGTTTGAGACCAGCCTGGTCAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAAT
TAGCCAGGCGTGGTGGTGCTCGCCTATAGTACCAGCTACTCAGGAGGCTGAGGCATAAGAATCACTTGAACCTGGGAGATGGAGGTTGCA
GTGAGCCGAGATCATGCCCCTGCACTCCAGCCTGGGTGACAGAGGGGGACTTGGCCTCGAAAAAATAAATAAATAATAAAAATAAAATAA

>42341_42341_5_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000414202_AARD_chr8_117954796_ENST00000378279_length(amino acids)=143AA_BP=127
MSVTDATGGAGGSARTMYFLSGWPKRLLCPLGSPAEAPFHVQSDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEW

--------------------------------------------------------------
>42341_42341_6_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000414202_AARD_chr8_117954797_ENST00000378279_length(transcript)=2453nt_BP=523nt
GTCAGCTTGGGGGTGCCTTCGTCGCGCAGCCTTGCGTCGGCCCGGCCCGGCCAGGCCAGCGGGCAGATGCCCCGAGCTGCCGCCGCCGCC
GCCGCCGACTCGGCCGGTGGCGGTGTGGGAGGTGGGCGACCAGCCCGGGGCCGCTGAGTGTGACGGACGCAACTGGGGGCGCCGGGGGCT
CCGCACGGACCATGTATTTTCTGAGCGGCTGGCCCAAGAGGCTGCTGTGCCCTCTGGGGAGCCCGGCCGAGGCGCCTTTCCACGTTCAGT
CCGACCCGCAGAGGGCTTTCTTCGCCGTGCTGGCCGCGGCCCGCCTCAGCATCTGGTACAGCCGACCTAGTGTGTTAATTGTAACCTACA
AGGAGCCTGCAAAATCATCTACTCAGTTTGGATCCTACAAGCAAGCTGAATGGAGGCCAGATAGTACCATGATAGCTGTATCAACGGCAA
ATGGATACATCTTGTTTTTTCATATTACATCTACAAGAGGGGACAAGTACCTTTATGAACCAGTGTATCCCAAGTGGAAATGCATTTCCA
AAACCACCAGCTGGCTAGAACTTTACTGGACCTAAACATGAAAGTGCAGCAATTGAAAAAGGAGTATGAACTGGAAATTACATCAGACTC
CCAAAGCCCAAAAGATGATGCTGCGAATCCGGAATAAAGAAATGCACACGCAAGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCA
CTTTGGGAGGCCGAGGCGGGCGGATCAAGACGTCAGGAGATTGAGACCATCCTGGCTAACACTGTGAAACCCTGCCTCTACTAAAAATAC
AAAAAATTAGCCAGACGTGGTGGCAGGCACCTGTAGTCCCTGCTACTCAGGAGTCTGAGGCAGGAGAATGGCGTGAACCCAGGAGACAGA
GCTTGCAGTGAGCCGAAATCCTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAGCA
CACGCGAAGCTCTGGATCCTAAAACTAACGCATACAACCCTGAAACAATTCTGATGAACACATTATGCTTTGCATAAGTTTTGAGGGGCA
ATTTATAGACCCAAAACAAATGACAGGGGAAGGTGACAGAAAAACATCTAAGAGAGGGGAGAGAAAAATGATGTATTACCAAGTTTTAAA
GTTATTTATTTGTTATTTTTACTGGGACATAGAAGTAAAATATAACTATAGATAAATCTCTCTCTGTCTCTCTCACTCAAAGAATGCTTT
AATGCCAACTTTCGGTATTCAACCTTGTGTCACCTGACCTTTCTGGCATTGCCTGAGCTTTCAGAGTTTGTGCTTGTTTTGTTTTACTTG
ATTATTCTCAGTTTGTCTGTCCAGCAGCCTGCCCTGCTTCTTGTGGAGAATTGTTTCTACTTGGATTCTAACCATGCCCTTTAGGTGGTC
TGTGACTAAGGGTATTCCATCTTCCTGGATATAGTCATGCAGCTCAAGGCAGGCAGATGGGTTTGTCCTTAGGATTTTTGAATGGGCACT
AAAAGAGTAGATGACTATTTCTGCCAGTAGAAGCTGTGGATCAGGGGCTTGGAAGCTGCTGGTGGTCACCATGTGAGAAAGCCCACACCC
TAATGGAGGTGACTGAAACGGAACCACTAAAAGCACAAAAGGGGAGGGAGGGAGGGAGGGTGCTTCGCTTCCTTGTTCCTGGGGTCAAGC
TGTATAAGACTCCAGGCCTTGCTCTTGTTTATGTACATGAAATATTCTGATATCCTTCTCATAAAATCTCTTTTTGCCTAAGTAAATTCA
AGCTGGAGTTTCATGACTTGTATCTAGTGTTCATAACTAATACAGTTGTTCAGTTTTAGGAGTTAAAATGGTTCTTACTGTTGAATTGGA
CTATCTAACTGTACCCGAAAAGTGCTGTCTTTTTAATGCAAACAGTAAAGTTAATAAAAAATAGTTGCAGATCTAAGTGATATTTATAAT
GGTTATTGTCTGCAAAATACAAATTAATTTATAACAAGCTATGTAATTTTAATATTTAATAAACTATAAAAATCAGTTCTTGAAGACAAA
GGAGAACAGAAGAGACACAGTCTTTCTCTTGTTAAAAGAAATACAAGGACAAGCATGGTGGATCACGCTTGTAATTCCAGCACTTTGGGA
GGCTGAGGTGGGCAGATTGTTTGAGCTCAGGAGTTTGAGACCAGCCTGGTCAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAAT
TAGCCAGGCGTGGTGGTGCTCGCCTATAGTACCAGCTACTCAGGAGGCTGAGGCATAAGAATCACTTGAACCTGGGAGATGGAGGTTGCA
GTGAGCCGAGATCATGCCCCTGCACTCCAGCCTGGGTGACAGAGGGGGACTTGGCCTCGAAAAAATAAATAAATAATAAAAATAAAATAA

>42341_42341_6_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000414202_AARD_chr8_117954797_ENST00000378279_length(amino acids)=143AA_BP=127
MSVTDATGGAGGSARTMYFLSGWPKRLLCPLGSPAEAPFHVQSDPQRAFFAVLAAARLSIWYSRPSVLIVTYKEPAKSSTQFGSYKQAEW

--------------------------------------------------------------
>42341_42341_7_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000418622_AARD_chr8_117954796_ENST00000378279_length(transcript)=2118nt_BP=188nt
CCTAGTGTGTTAATTGTAACCTACAAGGAGCCTGCAAAATCATCTACTCAGTTTGGATCCTACAAGCAAGCTGAATGGAGGCCAGATAGT
ACCATGATAGCTGTATCAACGGCAAATGGATACATCTTGTTTTTTCATATTACATCTACAAGAGGGGACAAGTACCTTTATGAACCAGTG
TATCCCAAGTGGAAATGCATTTCCAAAACCACCAGCTGGCTAGAACTTTACTGGACCTAAACATGAAAGTGCAGCAATTGAAAAAGGAGT
ATGAACTGGAAATTACATCAGACTCCCAAAGCCCAAAAGATGATGCTGCGAATCCGGAATAAAGAAATGCACACGCAAGGGCTGGGCGCG
GTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCAAGACGTCAGGAGATTGAGACCATCCTGGCTAACACTGT
GAAACCCTGCCTCTACTAAAAATACAAAAAATTAGCCAGACGTGGTGGCAGGCACCTGTAGTCCCTGCTACTCAGGAGTCTGAGGCAGGA
GAATGGCGTGAACCCAGGAGACAGAGCTTGCAGTGAGCCGAAATCCTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTC
AAAAAAAAAAAAAAAAAAAAAAGCACACGCGAAGCTCTGGATCCTAAAACTAACGCATACAACCCTGAAACAATTCTGATGAACACATTA
TGCTTTGCATAAGTTTTGAGGGGCAATTTATAGACCCAAAACAAATGACAGGGGAAGGTGACAGAAAAACATCTAAGAGAGGGGAGAGAA
AAATGATGTATTACCAAGTTTTAAAGTTATTTATTTGTTATTTTTACTGGGACATAGAAGTAAAATATAACTATAGATAAATCTCTCTCT
GTCTCTCTCACTCAAAGAATGCTTTAATGCCAACTTTCGGTATTCAACCTTGTGTCACCTGACCTTTCTGGCATTGCCTGAGCTTTCAGA
GTTTGTGCTTGTTTTGTTTTACTTGATTATTCTCAGTTTGTCTGTCCAGCAGCCTGCCCTGCTTCTTGTGGAGAATTGTTTCTACTTGGA
TTCTAACCATGCCCTTTAGGTGGTCTGTGACTAAGGGTATTCCATCTTCCTGGATATAGTCATGCAGCTCAAGGCAGGCAGATGGGTTTG
TCCTTAGGATTTTTGAATGGGCACTAAAAGAGTAGATGACTATTTCTGCCAGTAGAAGCTGTGGATCAGGGGCTTGGAAGCTGCTGGTGG
TCACCATGTGAGAAAGCCCACACCCTAATGGAGGTGACTGAAACGGAACCACTAAAAGCACAAAAGGGGAGGGAGGGAGGGAGGGTGCTT
CGCTTCCTTGTTCCTGGGGTCAAGCTGTATAAGACTCCAGGCCTTGCTCTTGTTTATGTACATGAAATATTCTGATATCCTTCTCATAAA
ATCTCTTTTTGCCTAAGTAAATTCAAGCTGGAGTTTCATGACTTGTATCTAGTGTTCATAACTAATACAGTTGTTCAGTTTTAGGAGTTA
AAATGGTTCTTACTGTTGAATTGGACTATCTAACTGTACCCGAAAAGTGCTGTCTTTTTAATGCAAACAGTAAAGTTAATAAAAAATAGT
TGCAGATCTAAGTGATATTTATAATGGTTATTGTCTGCAAAATACAAATTAATTTATAACAAGCTATGTAATTTTAATATTTAATAAACT
ATAAAAATCAGTTCTTGAAGACAAAGGAGAACAGAAGAGACACAGTCTTTCTCTTGTTAAAAGAAATACAAGGACAAGCATGGTGGATCA
CGCTTGTAATTCCAGCACTTTGGGAGGCTGAGGTGGGCAGATTGTTTGAGCTCAGGAGTTTGAGACCAGCCTGGTCAACATGGCAAAACC
CCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCTCGCCTATAGTACCAGCTACTCAGGAGGCTGAGGCATAAGAATCAC
TTGAACCTGGGAGATGGAGGTTGCAGTGAGCCGAGATCATGCCCCTGCACTCCAGCCTGGGTGACAGAGGGGGACTTGGCCTCGAAAAAA

>42341_42341_7_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000418622_AARD_chr8_117954796_ENST00000378279_length(amino acids)=101AA_BP=
MVIHHFSLPSLRCFSVTFPCHLFWVYKLPLKTYAKHNVFIRIVSGLYALVLGSRASRVLFFFFFFLRWSLALSPRLECSGRISAHCKLCL

--------------------------------------------------------------
>42341_42341_8_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000418622_AARD_chr8_117954797_ENST00000378279_length(transcript)=2118nt_BP=188nt
CCTAGTGTGTTAATTGTAACCTACAAGGAGCCTGCAAAATCATCTACTCAGTTTGGATCCTACAAGCAAGCTGAATGGAGGCCAGATAGT
ACCATGATAGCTGTATCAACGGCAAATGGATACATCTTGTTTTTTCATATTACATCTACAAGAGGGGACAAGTACCTTTATGAACCAGTG
TATCCCAAGTGGAAATGCATTTCCAAAACCACCAGCTGGCTAGAACTTTACTGGACCTAAACATGAAAGTGCAGCAATTGAAAAAGGAGT
ATGAACTGGAAATTACATCAGACTCCCAAAGCCCAAAAGATGATGCTGCGAATCCGGAATAAAGAAATGCACACGCAAGGGCTGGGCGCG
GTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCAAGACGTCAGGAGATTGAGACCATCCTGGCTAACACTGT
GAAACCCTGCCTCTACTAAAAATACAAAAAATTAGCCAGACGTGGTGGCAGGCACCTGTAGTCCCTGCTACTCAGGAGTCTGAGGCAGGA
GAATGGCGTGAACCCAGGAGACAGAGCTTGCAGTGAGCCGAAATCCTGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCATCTC
AAAAAAAAAAAAAAAAAAAAAAGCACACGCGAAGCTCTGGATCCTAAAACTAACGCATACAACCCTGAAACAATTCTGATGAACACATTA
TGCTTTGCATAAGTTTTGAGGGGCAATTTATAGACCCAAAACAAATGACAGGGGAAGGTGACAGAAAAACATCTAAGAGAGGGGAGAGAA
AAATGATGTATTACCAAGTTTTAAAGTTATTTATTTGTTATTTTTACTGGGACATAGAAGTAAAATATAACTATAGATAAATCTCTCTCT
GTCTCTCTCACTCAAAGAATGCTTTAATGCCAACTTTCGGTATTCAACCTTGTGTCACCTGACCTTTCTGGCATTGCCTGAGCTTTCAGA
GTTTGTGCTTGTTTTGTTTTACTTGATTATTCTCAGTTTGTCTGTCCAGCAGCCTGCCCTGCTTCTTGTGGAGAATTGTTTCTACTTGGA
TTCTAACCATGCCCTTTAGGTGGTCTGTGACTAAGGGTATTCCATCTTCCTGGATATAGTCATGCAGCTCAAGGCAGGCAGATGGGTTTG
TCCTTAGGATTTTTGAATGGGCACTAAAAGAGTAGATGACTATTTCTGCCAGTAGAAGCTGTGGATCAGGGGCTTGGAAGCTGCTGGTGG
TCACCATGTGAGAAAGCCCACACCCTAATGGAGGTGACTGAAACGGAACCACTAAAAGCACAAAAGGGGAGGGAGGGAGGGAGGGTGCTT
CGCTTCCTTGTTCCTGGGGTCAAGCTGTATAAGACTCCAGGCCTTGCTCTTGTTTATGTACATGAAATATTCTGATATCCTTCTCATAAA
ATCTCTTTTTGCCTAAGTAAATTCAAGCTGGAGTTTCATGACTTGTATCTAGTGTTCATAACTAATACAGTTGTTCAGTTTTAGGAGTTA
AAATGGTTCTTACTGTTGAATTGGACTATCTAACTGTACCCGAAAAGTGCTGTCTTTTTAATGCAAACAGTAAAGTTAATAAAAAATAGT
TGCAGATCTAAGTGATATTTATAATGGTTATTGTCTGCAAAATACAAATTAATTTATAACAAGCTATGTAATTTTAATATTTAATAAACT
ATAAAAATCAGTTCTTGAAGACAAAGGAGAACAGAAGAGACACAGTCTTTCTCTTGTTAAAAGAAATACAAGGACAAGCATGGTGGATCA
CGCTTGTAATTCCAGCACTTTGGGAGGCTGAGGTGGGCAGATTGTTTGAGCTCAGGAGTTTGAGACCAGCCTGGTCAACATGGCAAAACC
CCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCTCGCCTATAGTACCAGCTACTCAGGAGGCTGAGGCATAAGAATCAC
TTGAACCTGGGAGATGGAGGTTGCAGTGAGCCGAGATCATGCCCCTGCACTCCAGCCTGGGTGACAGAGGGGGACTTGGCCTCGAAAAAA

>42341_42341_8_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000418622_AARD_chr8_117954797_ENST00000378279_length(amino acids)=101AA_BP=
MVIHHFSLPSLRCFSVTFPCHLFWVYKLPLKTYAKHNVFIRIVSGLYALVLGSRASRVLFFFFFFLRWSLALSPRLECSGRISAHCKLCL

--------------------------------------------------------------
>42341_42341_9_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000449720_AARD_chr8_117954796_ENST00000378279_length(transcript)=2047nt_BP=117nt
TGAATGGAGGCCAGATAGTACCATGATAGCTGTATCAACGGCAAATGGATACATCTTGTTTTTTCATATTACATCTACAAGAGGGGACAA
GTACCTTTATGAACCAGTGTATCCCAAGTGGAAATGCATTTCCAAAACCACCAGCTGGCTAGAACTTTACTGGACCTAAACATGAAAGTG
CAGCAATTGAAAAAGGAGTATGAACTGGAAATTACATCAGACTCCCAAAGCCCAAAAGATGATGCTGCGAATCCGGAATAAAGAAATGCA
CACGCAAGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCAAGACGTCAGGAGATTGAGA
CCATCCTGGCTAACACTGTGAAACCCTGCCTCTACTAAAAATACAAAAAATTAGCCAGACGTGGTGGCAGGCACCTGTAGTCCCTGCTAC
TCAGGAGTCTGAGGCAGGAGAATGGCGTGAACCCAGGAGACAGAGCTTGCAGTGAGCCGAAATCCTGCCACTGCACTCCAGCCTGGGTGA
CAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAGCACACGCGAAGCTCTGGATCCTAAAACTAACGCATACAACCCTGAAAC
AATTCTGATGAACACATTATGCTTTGCATAAGTTTTGAGGGGCAATTTATAGACCCAAAACAAATGACAGGGGAAGGTGACAGAAAAACA
TCTAAGAGAGGGGAGAGAAAAATGATGTATTACCAAGTTTTAAAGTTATTTATTTGTTATTTTTACTGGGACATAGAAGTAAAATATAAC
TATAGATAAATCTCTCTCTGTCTCTCTCACTCAAAGAATGCTTTAATGCCAACTTTCGGTATTCAACCTTGTGTCACCTGACCTTTCTGG
CATTGCCTGAGCTTTCAGAGTTTGTGCTTGTTTTGTTTTACTTGATTATTCTCAGTTTGTCTGTCCAGCAGCCTGCCCTGCTTCTTGTGG
AGAATTGTTTCTACTTGGATTCTAACCATGCCCTTTAGGTGGTCTGTGACTAAGGGTATTCCATCTTCCTGGATATAGTCATGCAGCTCA
AGGCAGGCAGATGGGTTTGTCCTTAGGATTTTTGAATGGGCACTAAAAGAGTAGATGACTATTTCTGCCAGTAGAAGCTGTGGATCAGGG
GCTTGGAAGCTGCTGGTGGTCACCATGTGAGAAAGCCCACACCCTAATGGAGGTGACTGAAACGGAACCACTAAAAGCACAAAAGGGGAG
GGAGGGAGGGAGGGTGCTTCGCTTCCTTGTTCCTGGGGTCAAGCTGTATAAGACTCCAGGCCTTGCTCTTGTTTATGTACATGAAATATT
CTGATATCCTTCTCATAAAATCTCTTTTTGCCTAAGTAAATTCAAGCTGGAGTTTCATGACTTGTATCTAGTGTTCATAACTAATACAGT
TGTTCAGTTTTAGGAGTTAAAATGGTTCTTACTGTTGAATTGGACTATCTAACTGTACCCGAAAAGTGCTGTCTTTTTAATGCAAACAGT
AAAGTTAATAAAAAATAGTTGCAGATCTAAGTGATATTTATAATGGTTATTGTCTGCAAAATACAAATTAATTTATAACAAGCTATGTAA
TTTTAATATTTAATAAACTATAAAAATCAGTTCTTGAAGACAAAGGAGAACAGAAGAGACACAGTCTTTCTCTTGTTAAAAGAAATACAA
GGACAAGCATGGTGGATCACGCTTGTAATTCCAGCACTTTGGGAGGCTGAGGTGGGCAGATTGTTTGAGCTCAGGAGTTTGAGACCAGCC
TGGTCAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCTCGCCTATAGTACCAGCTACTCAGGAG
GCTGAGGCATAAGAATCACTTGAACCTGGGAGATGGAGGTTGCAGTGAGCCGAGATCATGCCCCTGCACTCCAGCCTGGGTGACAGAGGG

>42341_42341_9_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000449720_AARD_chr8_117954796_ENST00000378279_length(amino acids)=101AA_BP=
MVIHHFSLPSLRCFSVTFPCHLFWVYKLPLKTYAKHNVFIRIVSGLYALVLGSRASRVLFFFFFFLRWSLALSPRLECSGRISAHCKLCL

--------------------------------------------------------------
>42341_42341_10_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000449720_AARD_chr8_117954797_ENST00000378279_length(transcript)=2047nt_BP=117nt
TGAATGGAGGCCAGATAGTACCATGATAGCTGTATCAACGGCAAATGGATACATCTTGTTTTTTCATATTACATCTACAAGAGGGGACAA
GTACCTTTATGAACCAGTGTATCCCAAGTGGAAATGCATTTCCAAAACCACCAGCTGGCTAGAACTTTACTGGACCTAAACATGAAAGTG
CAGCAATTGAAAAAGGAGTATGAACTGGAAATTACATCAGACTCCCAAAGCCCAAAAGATGATGCTGCGAATCCGGAATAAAGAAATGCA
CACGCAAGGGCTGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCAAGACGTCAGGAGATTGAGA
CCATCCTGGCTAACACTGTGAAACCCTGCCTCTACTAAAAATACAAAAAATTAGCCAGACGTGGTGGCAGGCACCTGTAGTCCCTGCTAC
TCAGGAGTCTGAGGCAGGAGAATGGCGTGAACCCAGGAGACAGAGCTTGCAGTGAGCCGAAATCCTGCCACTGCACTCCAGCCTGGGTGA
CAGAGCAAGACTCCATCTCAAAAAAAAAAAAAAAAAAAAAAGCACACGCGAAGCTCTGGATCCTAAAACTAACGCATACAACCCTGAAAC
AATTCTGATGAACACATTATGCTTTGCATAAGTTTTGAGGGGCAATTTATAGACCCAAAACAAATGACAGGGGAAGGTGACAGAAAAACA
TCTAAGAGAGGGGAGAGAAAAATGATGTATTACCAAGTTTTAAAGTTATTTATTTGTTATTTTTACTGGGACATAGAAGTAAAATATAAC
TATAGATAAATCTCTCTCTGTCTCTCTCACTCAAAGAATGCTTTAATGCCAACTTTCGGTATTCAACCTTGTGTCACCTGACCTTTCTGG
CATTGCCTGAGCTTTCAGAGTTTGTGCTTGTTTTGTTTTACTTGATTATTCTCAGTTTGTCTGTCCAGCAGCCTGCCCTGCTTCTTGTGG
AGAATTGTTTCTACTTGGATTCTAACCATGCCCTTTAGGTGGTCTGTGACTAAGGGTATTCCATCTTCCTGGATATAGTCATGCAGCTCA
AGGCAGGCAGATGGGTTTGTCCTTAGGATTTTTGAATGGGCACTAAAAGAGTAGATGACTATTTCTGCCAGTAGAAGCTGTGGATCAGGG
GCTTGGAAGCTGCTGGTGGTCACCATGTGAGAAAGCCCACACCCTAATGGAGGTGACTGAAACGGAACCACTAAAAGCACAAAAGGGGAG
GGAGGGAGGGAGGGTGCTTCGCTTCCTTGTTCCTGGGGTCAAGCTGTATAAGACTCCAGGCCTTGCTCTTGTTTATGTACATGAAATATT
CTGATATCCTTCTCATAAAATCTCTTTTTGCCTAAGTAAATTCAAGCTGGAGTTTCATGACTTGTATCTAGTGTTCATAACTAATACAGT
TGTTCAGTTTTAGGAGTTAAAATGGTTCTTACTGTTGAATTGGACTATCTAACTGTACCCGAAAAGTGCTGTCTTTTTAATGCAAACAGT
AAAGTTAATAAAAAATAGTTGCAGATCTAAGTGATATTTATAATGGTTATTGTCTGCAAAATACAAATTAATTTATAACAAGCTATGTAA
TTTTAATATTTAATAAACTATAAAAATCAGTTCTTGAAGACAAAGGAGAACAGAAGAGACACAGTCTTTCTCTTGTTAAAAGAAATACAA
GGACAAGCATGGTGGATCACGCTTGTAATTCCAGCACTTTGGGAGGCTGAGGTGGGCAGATTGTTTGAGCTCAGGAGTTTGAGACCAGCC
TGGTCAACATGGCAAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGCGTGGTGGTGCTCGCCTATAGTACCAGCTACTCAGGAG
GCTGAGGCATAAGAATCACTTGAACCTGGGAGATGGAGGTTGCAGTGAGCCGAGATCATGCCCCTGCACTCCAGCCTGGGTGACAGAGGG

>42341_42341_10_KIAA1432-AARD_KIAA1432_chr9_5690038_ENST00000449720_AARD_chr8_117954797_ENST00000378279_length(amino acids)=101AA_BP=
MVIHHFSLPSLRCFSVTFPCHLFWVYKLPLKTYAKHNVFIRIVSGLYALVLGSRASRVLFFFFFFLRWSLALSPRLECSGRISAHCKLCL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for KIAA1432-AARD


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for KIAA1432-AARD


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for KIAA1432-AARD


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource