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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:KIDINS220-C3orf70 (FusionGDB2 ID:42502)

Fusion Gene Summary for KIDINS220-C3orf70

Fusion gene summary

Fusion gene information	Fusion gene name: KIDINS220-C3orf70
	Fusion gene ID: 42502
		Hgene	Tgene
	Gene symbol	KIDINS220	C3orf70
	Gene ID	57498	285382
	Gene name	kinase D interacting substrate 220	chromosome 3 open reading frame 70
	Synonyms	ARMS\|SINO	-
	Cytomap	2p25.1	3q27.2
	Type of gene	protein-coding	protein-coding
	Description	kinase D-interacting substrate of 220 kDaankyrin repeat-rich membrane-spanning proteinkinase D-interacting substrate 220kDa	UPF0524 protein C3orf70
	Modification date	20200313	20200313
	UniProtAcc	Q9ULH0	A6NLC5
	Ensembl transtripts involved in fusion gene	ENST00000418530, ENST00000473731, ENST00000256707, ENST00000319688, ENST00000427284, ENST00000436566,	ENST00000335012,
Fusion gene scores	* DoF score	13 X 11 X 9=1287	3 X 1 X 3=9
	# samples	11	3
	** MAII score	log2(11/1287*10)=-3.54843662469604 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: KIDINS220 [Title/Abstract] AND C3orf70 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	KIDINS220(8952525)-C3orf70(184801351), # samples:2
Anticipated loss of major functional domain due to fusion event.	KIDINS220-C3orf70 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across KIDINS220 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across C3orf70 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	GBM	TCGA-06-0171-02A	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-

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Fusion Gene ORF analysis for KIDINS220-C3orf70

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
Frame-shift	ENST00000418530	ENST00000335012	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-
Frame-shift	ENST00000473731	ENST00000335012	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-
In-frame	ENST00000256707	ENST00000335012	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-
In-frame	ENST00000319688	ENST00000335012	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-
In-frame	ENST00000427284	ENST00000335012	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-
intron-3CDS	ENST00000436566	ENST00000335012	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000256707	KIDINS220	chr2	8952525	-	ENST00000335012	C3orf70	chr3	184801351	-	6200	686	694	1242	182
ENST00000427284	KIDINS220	chr2	8952525	-	ENST00000335012	C3orf70	chr3	184801351	-	6200	686	694	1242	182
ENST00000319688	KIDINS220	chr2	8952525	-	ENST00000335012	C3orf70	chr3	184801351	-	6178	664	672	1220	182

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000256707	ENST00000335012	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-	0.003240655	0.99675936
ENST00000427284	ENST00000335012	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-	0.003240655	0.99675936
ENST00000319688	ENST00000335012	KIDINS220	chr2	8952525	-	C3orf70	chr3	184801351	-	0.003235477	0.99676454

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Fusion Genomic Features for KIDINS220-C3orf70

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KIDINS220-C3orf70

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:8952525/chr3:184801351)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
KIDINS220 Q9ULH0	C3orf70 A6NLC5
FUNCTION: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway. {ECO:0000250, ECO:0000269\|PubMed:18089783}.	FUNCTION: May play a role in neuronal and neurobehavioral development. {ECO:0000250\|UniProtKB:Q1LY84}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

103_132

168

1772.0

Repeat

Note=ANK 4

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

136_165

168

1772.0

Repeat

Note=ANK 5

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

37_66

168

1772.0

Repeat

Note=ANK 2

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

4_33

168

1772.0

Repeat

Note=ANK 1

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

70_99

168

1772.0

Repeat

Note=ANK 3

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

103_132

169

1032.0

Repeat

Note=ANK 4

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

136_165

169

1032.0

Repeat

Note=ANK 5

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

37_66

169

1032.0

Repeat

Note=ANK 2

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

4_33

169

1032.0

Repeat

Note=ANK 1

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

70_99

169

1032.0

Repeat

Note=ANK 3

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

37_66

126

1673.0

Repeat

Note=ANK 2

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

4_33

126

1673.0

Repeat

Note=ANK 1

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

70_99

126

1673.0

Repeat

Note=ANK 3

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

103_132

168

1753.0

Repeat

Note=ANK 4

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

136_165

168

1753.0

Repeat

Note=ANK 5

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

37_66

168

1753.0

Repeat

Note=ANK 2

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

4_33

168

1753.0

Repeat

Note=ANK 1

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

70_99

168

1753.0

Repeat

Note=ANK 3

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

103_132

168

1753.0

Repeat

Note=ANK 4

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

136_165

168

1753.0

Repeat

Note=ANK 5

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

37_66

168

1753.0

Repeat

Note=ANK 2

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

4_33

168

1753.0

Repeat

Note=ANK 1

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

70_99

168

1753.0

Repeat

Note=ANK 3

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

440_953

168

1772.0

Domain

Note=KAP NTPase

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

440_953

169

1032.0

Domain

Note=KAP NTPase

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

440_953

126

1673.0

Domain

Note=KAP NTPase

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

440_953

168

1753.0

Domain

Note=KAP NTPase

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

440_953

168

1753.0

Domain

Note=KAP NTPase

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

1766_1771

168

1772.0

Motif

PDZ-binding

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

1766_1771

169

1032.0

Motif

PDZ-binding

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

1766_1771

126

1673.0

Motif

PDZ-binding

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

1766_1771

168

1753.0

Motif

PDZ-binding

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

1766_1771

168

1753.0

Motif

PDZ-binding

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

169_198

168

1772.0

Repeat

Note=ANK 6

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

202_231

168

1772.0

Repeat

Note=ANK 7

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

235_264

168

1772.0

Repeat

Note=ANK 8

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

268_297

168

1772.0

Repeat

Note=ANK 9

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

301_330

168

1772.0

Repeat

Note=ANK 10

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

334_363

168

1772.0

Repeat

Note=ANK 11

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

367_396

168

1772.0

Repeat

Note=ANK 12

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

169_198

169

1032.0

Repeat

Note=ANK 6

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

202_231

169

1032.0

Repeat

Note=ANK 7

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

235_264

169

1032.0

Repeat

Note=ANK 8

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

268_297

169

1032.0

Repeat

Note=ANK 9

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

301_330

169

1032.0

Repeat

Note=ANK 10

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

334_363

169

1032.0

Repeat

Note=ANK 11

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

367_396

169

1032.0

Repeat

Note=ANK 12

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

103_132

126

1673.0

Repeat

Note=ANK 4

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

136_165

126

1673.0

Repeat

Note=ANK 5

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

169_198

126

1673.0

Repeat

Note=ANK 6

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

202_231

126

1673.0

Repeat

Note=ANK 7

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

235_264

126

1673.0

Repeat

Note=ANK 8

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

268_297

126

1673.0

Repeat

Note=ANK 9

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

301_330

126

1673.0

Repeat

Note=ANK 10

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

334_363

126

1673.0

Repeat

Note=ANK 11

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

367_396

126

1673.0

Repeat

Note=ANK 12

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

169_198

168

1753.0

Repeat

Note=ANK 6

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

202_231

168

1753.0

Repeat

Note=ANK 7

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

235_264

168

1753.0

Repeat

Note=ANK 8

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

268_297

168

1753.0

Repeat

Note=ANK 9

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

301_330

168

1753.0

Repeat

Note=ANK 10

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

334_363

168

1753.0

Repeat

Note=ANK 11

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

367_396

168

1753.0

Repeat

Note=ANK 12

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

169_198

168

1753.0

Repeat

Note=ANK 6

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

202_231

168

1753.0

Repeat

Note=ANK 7

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

235_264

168

1753.0

Repeat

Note=ANK 8

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

268_297

168

1753.0

Repeat

Note=ANK 9

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

301_330

168

1753.0

Repeat

Note=ANK 10

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

334_363

168

1753.0

Repeat

Note=ANK 11

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

367_396

168

1753.0

Repeat

Note=ANK 12

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

1_499

168

1772.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

521_524

168

1772.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

546_659

168

1772.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

681_685

168

1772.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

707_1771

168

1772.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

1_499

169

1032.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

521_524

169

1032.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

546_659

169

1032.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

681_685

169

1032.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

707_1771

169

1032.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

1_499

126

1673.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

521_524

126

1673.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

546_659

126

1673.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

681_685

126

1673.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

707_1771

126

1673.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

1_499

168

1753.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

521_524

168

1753.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

546_659

168

1753.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

681_685

168

1753.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

707_1771

168

1753.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

1_499

168

1753.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

521_524

168

1753.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

546_659

168

1753.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

681_685

168

1753.0

Topological domain

Extracellular

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

707_1771

168

1753.0

Topological domain

Cytoplasmic

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

500_520

168

1772.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

525_545

168

1772.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

660_680

168

1772.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000256707

686_706

168

1772.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

500_520

169

1032.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

525_545

169

1032.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

660_680

169

1032.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000319688

686_706

169

1032.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

500_520

126

1673.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

525_545

126

1673.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

660_680

126

1673.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000418530

686_706

126

1673.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

500_520

168

1753.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

525_545

168

1753.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

660_680

168

1753.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000427284

686_706

168

1753.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

500_520

168

1753.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

525_545

168

1753.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

660_680

168

1753.0

Transmembrane

Helical

Hgene

KIDINS220

chr2:8952525

chr3:184801351

ENST00000473731

686_706

168

1753.0

Transmembrane

Helical

Top

Fusion Gene Sequence for KIDINS220-C3orf70

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>42502_42502_1_KIDINS220-C3orf70_KIDINS220_chr2_8952525_ENST00000256707_C3orf70_chr3_184801351_ENST00000335012_length(transcript)=6200nt_BP=686nt
ACGTGATCTGTCAGTTCGCGGAGAGGGAAGAATATGGCCGCCGGGTGTGGTGAGGGCGACGCGCTTGCAGTCGCCGTCTCTTGCTTCCCC
GTCCTCTGACATCGCCTGCAGCCGAGCGGGCCCGTTCCGCCGGAGCTGAGGACCAGGTATTCAAATAAAGTTAATTGCAGCTTTCTGTGA
AAATGTCAGTTTTGATATCACAGAGCGTCATAAATTATGTAGAGGAAGAAAACATTCCTGCTCTGAAAGCTCTTCTTGAAAAATGCAAAG
ATGTAGATGAGAGAAATGAGTGTGGCCAGACTCCACTGATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGA
ATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGGACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAAC
TACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATGGGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAG
TAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTCACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATG
CAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAAGTCAACTGCTCTGATAAGGCAAATACATGTATCAGCCTATGACCCCTGTGGA
ACAGCTTCCAAGCACTGAGATTCCTGCCAGGCCTCGGGAACCCACAAACACCATTCAGATCTCAGTCTCGCTCACCGAACACTTTTTGAA
ATTTGCATCTGTCTTCCAGCCTCCCCTTCCCCCTGACTCACCGAGGTACTGTATGATTTCAGACCTTTTTATTGACAACTATCAGGTTAA
ATGTATTAATGGGAAGATGTGTTATGTGCAGAAGCAGCCGGCACCACATTCCCACAGAATGAGCCCTGAGGAGGTCTCTGCACACGATGC
CTTAATTTCAAAAGAGAGCAATACACCAAAAATAGATCACTGCTCTTCTCCCTCAAGTTCTGAGGACTCTGGGATCAATGCGATTGGGGC
TCACTATGTGGAATCGTGTGACGAGGACACAGAAGAAGGAGCAGAACTGAGTTCAGAGGAAGATTACAGTCCAGAGAGCAGCTGGGAACC
GGATGAGTGCACCCTTCTCTCCCCCTCGCAGTCTGACCTGGAAGTGATTGAAACGATAGAAACGACTGTGTGAGAGTCCAGACAGGAAGC
CACAGCCTCGGACCCACGCCGAGCTTTTGTACCTTTGTCTGGTGGATCCTTTTTTCCAATGCTGTTGATATTTTCTACCCACCCCGCCCC
GCTCCAACCAACAACCGTAGCAGTTCAGTGGTATGCTGATTAGCTTCTCTCCGTCTTACAACTAAGACATTCTTTTTATTATAAACAGTT
TTCTTTTGTATCCTGACTTACTTTCTATGTAGCATCTGGTGTCATGAATTGTGACCCCGCCTTAATTTCACTGGGAGATTTGAAGGCGGT
GAAGTGATGGTCGCAGAGAATCTTGGATCAGATTGAGGAGGTACCGAAAGGGAAGGAGCCGGTGTTTTCTCGGTAGCCAGTCCTTCACAG
AGACTCTTGCCATTCCCTTTGGCATGTTCACAGGCACTCCCGTCCTGTCCTGCTTGTCCTACGCAAGTAGCACTCCCTACTGAGTGTGCA
CTGGTAGATGCCGTTTCTTCCCTTCCCCTTCTCCCCACACCTGCACTGGGTCTGGATCAGAGCTGCCTCGGCTTACTTCTGGGAGGTCAC
TGGAGGCCAGCTCAGCCCATGGTTTGTGGCCAGTGTCTGTACAAGGCTCCGTGACTGGGGCTGAGCTAAACATTCACATGAGAAGAGATG
ACCTCATCTGTCTCATGCTCAATCCAGCCTTAGCTGAGCACCTGTCCCCTGCAGGGGGCTGTGGGGACACAGCATGAATAAGACCTGATT
CCCACCATGAAGGGGCCCACAGTCCTATATATGACACATTCAACTCATGGCACCCAAAAAGCTCTGGGAACCCAGGGGAAGGATGAGGTT
TACTTGGCTGGGGCTAGCTGGGGAATGTGTTTCAGCATTTGAGCTGGCTTCTTGGTGGGTTCCCCAACATTTTTCTGCTTTTAATTGTTC
TTCAAGTCTGGGAAAAACTCTTAGGAAGTTATATAGGTATCACATTTAGGTGGCAGCCACATCTGACATCTTAAGGAAAAAAAATAAATT
AATAGTTTTAGTTAGCATGGAAATGCTACAGACAGAAGCCCTTTAGGGATTAGGACTGAATCTAATAGGTTTGATTAATTCTGCTTCATT
TGGTTGTATGAAGCATTCGTATGGTTTAAGTGAGGAATGGATTAGAATTCAGTGTGATGCATGGATTTTTATGCAGCTGCAAAAGCAGTT
GAAATAGTTTGCTGCTAAGTCAGGAGAAAATATCCAGTGTAATAGCCATTCACTTTCCCACACAGTCTGTCTGTTGTATGTGTTCTCTCC
CCTCACATGCACAAAATAGTGACTAATTCTTTCTTATTTAGCTCTCTTCAGAATTCTACTTCTACTCTCCATTTATACCAGGTATTCTTG
TGAGTCAGTTAACTGCTATTTCTCCAAACCTTCTATCCATGAGGCATAGTTTCAAATCCTGGAAATTTTAAGTATGGCCTAATGAGAACA
TCAGAGTTGGAGACAGAACAGTACTTCCATCCTAACTATCCAGAAGCGCACTCTCAGGCCATTGTGCTCTGAGATTCCCTTGTGCTCTGG
CACCATTATGGTACATCTCTACGTCACATTAATTTTTTTTTTTTTGAGATGGAGTTTCCCTCTTGCTGCCCAGGCTGGAGTGCAGCGGCG
TGATCTTGGCTCTCTACAACCTCTGCCTCCTGGGGTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTATGGGCACGTGCC
ACCACACCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGGCTTTCACCATGTTAGCCAGGATGGTCTCGATCTGACCTTGTGATCCACC
CACCTCGGCCTCCCCAAGTGCTGGGATTACAAGCATGAGCCACCACGCCCGGCCGGATTTGTAAGAAAAAGTTGTGTTCTCCCCTGAAGC
CTCCATTTGGCATCATTCACAAACTACTCAAGGAAGAATTTGCTTTCCCAGTTGTATGTATAATTTAAGTCGTTTACTAGATAGAACTTT
TTTTTAGGTTTAGATGGCCAAGACATCTATATGGTTTAGAAGGCAGAGTATACATTTTCCTTTGCAAACAGTATGAGTTAAAACTTTCTA
TGCTAAATGAGAATGCGGCATAAAGTCTCCACTTACTGAAATTTAAAGATTCAACAAGACAAACCGAGAAGGGGGTCAGAGGAGCTCTAG
GAAAGGCCCAGGAGAGGGCAGTTGGAGGCAGGTGTGAGCATGAGGAGCTTCCCCCTGCCAGGGCATGGCTCAGGTGGCACAGGGACATCT
GATGAACCCTGCCCGAGGTTCTCGGTGCCTCCCGTGCATGAGTGGCTCACTGAAGGCAGGTGTGGAAGCCAAATGCCTGCAAGCCGTGTG
TCAGGCCACAGCAGTGCAGTCATGCATCACGCACTCAGGTTTGTAACAGCAACACCAGGGCCCTGTCTAGATTCACCCTGTGGGTGAGCC
CGTTCTCCAGATGGGCGTATAAAGGGGCTTTCTCCTCTACACCGTTCCTGTCAATGTTCCGTACAGGCCCACATTCCCACCACTAAGCCA
ATGGAGTCAACCAGATTTCTAAAGCCATGGATATACGTGGTCACGGGGCCACATTTCTGCAGCTGGCTCAGTGGCAGGCTTGGGCCGTCT
CTCAGTACCATCTAAGACTTCTGTCTAGGTTCCTGTTTTTTTAGACTCCTGAACTGCCATTCTGATTAGACACAATTTTAATGGAATTTT
TGGATTTAATAATAGTTGATAATCACCTTATGTATTTGCACAATCTCTTTATAATTAAAAACTCGCTAAGCTTCACTTGCTACTATCTAC
TATATAGAATTAGAGACATTCCATTGGATTCTAAGCATCAGACACTCCTGGATCTCAAAATGACCTTTTCTAAATAAGCACAAGATTTAT
TTTTGTCCTAGCACTGTTGATAACACTCTGAAATATGTTATTGAACTGGAATTGTTTCTTTATGCTTGCATTCCAAAACCAACTGAAACA
GATTGTAGTTTCACTTTAAATTCTAGGCCTGTTCTATATTATGTGAAGGAATTCTCTGTAACGCTGATACTATGTTGCTAATTTGTGTAC
TTACAGACACTTTAGAAAATGTTTAGACTGCAACATGCACTATAACATTGAACTCAGTCACATGAAGTGGTTAACACTTGCACACTGACT
GACAGATATGAAAGCTGTATACTTTGGACCCAGTAATATGCTCATTGGAGCAAGGGTTGGGCTGTGTGGATGGATAAACTGCTTTCTTGG
GTTTACATGGAAACCTGGTACCACTCCTACTTTTGGAAAGTTGGTATAAAAGCTATTAGGTAGAAGCTTAATTCCACTAAATGTAGAATT
TAGTTTTCTTCTCTAACCAAGATTTTAGAAGTTTCAAGTTTCAAATATGCTTATAACTTTTCCAAGAAATGATGATTACAGTGCTTTTGT
GGTTACAACTGTTTGGTATATTAAAAAATAAGGGTTTACTATCACATCTAGGTCTTTTTTACTATGTCATTTTTAAGATATGAAATAAGA
ATCTGAGGACAGCCCTGAAGAACAGTCCTTTCCTGGGAGGGGAAGACTTGTAATTCAAGGTCATACAATACAAAATAAAACAAAAACAAA
AGCACCAAGAGCAGAACAAAACAACGTAGTTGCTTTCCTGAAATACTTTTTGGATTTGATTCTATCTTGGGAGTGGTGGCTTTACTTTTT
TTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCCTTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCCAGCTCTGCC
TCCCAGGTTCATGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTATAGGTGCCCGCCACCATGCCTCGCTAATTTTTTGTATTT
TTAGTAGAAACGGGGTTTCACCGTGTTAGCCAGGATGGTCTTGATCTCATGACCTCGTGATCCACCCTCCTCGGCTTCCCAAAGTGCTGG
GATTGCAGGCGTGAACCACCACGCCCGGCCGGCTTTACTTCTAATCCTCCACTTCTTGGTCTATTTGAACCATCACAAGTATTTTGGGAC
CGATAACAAACCCCTTTTATGCTAATTTAATTCTTGACTTGGGTAATAGGTGCACCTGGATAATTTATAAAGCTGTCCATAGATCTAAGT
TTAGTGGTACAGATACTACTGGGCAGGAGAAAAAGCACAAGTTAAAATATTTCTACAGTCAGCTCTTAATATTCCCACATCTTGTTTGCA
AAATTTTATGGTCACGTTCTGGCTTTTTTACATGAGGAAAACAAAGTTTTAACAGTTTTCTCTTCTGTCCCCTTCTCCAGAGGAGGTGTG
AACCAGAACTGAGGAGGCCAGTTATATTTTAGGCTTTTCAGTAGTACGATTTTGTCCTCTCCCACTGAGGAGGAGGGAAGAAGGGGGAAG
CCAGTGGGAGTTCCACACACGTGGTCAGTGCTGTAAGTTCCCGGATATCAGTGTCTCTCACATCAACACAGAAATAGGGCACTTCTCAAC
ATTAATTTTGGAATTATTCACCATTTAAAAATTGTCACTGCTCTTTTTCATTACTGTAGATAACTGAGAGTTAGCTGTTCTAGGAAAAGG
CCATGTTTCAGTTAGTGCTATGACTTCTTTTTTCGATTAAGGTTGAAGCAGTGTTCTCTTAGTAGCCTGAACACTTCTCAAAGCGACTTA
TCACTAGCGGCTTTAATATTGAGCTTCTATATCGTTGTGTCCACCTCACTTTTTAAGGCTGTTCATACCTGGCAATATTCACTTACTCTG
CTATTTTTAAAAACTATTTTAAAGTTTTAAGCACAATGTTGACTCTTCTGTAATTTCCTAAAATTATATTGTTTTCCTACAGACAGCTCA

>42502_42502_1_KIDINS220-C3orf70_KIDINS220_chr2_8952525_ENST00000256707_C3orf70_chr3_184801351_ENST00000335012_length(amino acids)=182AA_BP=
MYQPMTPVEQLPSTEIPARPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQPAPHSHRMS
PEEVSAHDALISKESNTPKIDHCSSPSSSEDSGINAIGAHYVESCDEDTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETIET

--------------------------------------------------------------
>42502_42502_2_KIDINS220-C3orf70_KIDINS220_chr2_8952525_ENST00000319688_C3orf70_chr3_184801351_ENST00000335012_length(transcript)=6178nt_BP=664nt
GGAAGAATATGGCCGCCGGGTGTGGTGAGGGCGACGCGCTTGCAGTCGCCGTCTCTTGCTTCCCCGTCCTCTGACATCGCCTGCAGCCGA
GCGGGCCCGTTCCGCCGGAGCTGAGGACCAGGTATTCAAATAAAGTTAATTGCAGCTTTCTGTGAAAATGTCAGTTTTGATATCACAGAG
CGTCATAAATTATGTAGAGGAAGAAAACATTCCTGCTCTGAAAGCTCTTCTTGAAAAATGCAAAGATGTAGATGAGAGAAATGAGTGTGG
CCAGACTCCACTGATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGAATGGAGCTAACTGCAATCTGGAAGA
TTTGGATAATTGGACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAACTACTGAAATGTGGGGTTAACTTGGA
GCACCGTGATATGGGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAGTAGAGTTGCTTCTTTCTCATGGTGC
CAATCCAAGTGTCACTGGTCTGCAGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATGCAGATATAGTTCATCTTTTACT
GCAAAATGGTGCTAAAGTCAACTGCTCTGATAAGGCAAATACATGTATCAGCCTATGACCCCTGTGGAACAGCTTCCAAGCACTGAGATT
CCTGCCAGGCCTCGGGAACCCACAAACACCATTCAGATCTCAGTCTCGCTCACCGAACACTTTTTGAAATTTGCATCTGTCTTCCAGCCT
CCCCTTCCCCCTGACTCACCGAGGTACTGTATGATTTCAGACCTTTTTATTGACAACTATCAGGTTAAATGTATTAATGGGAAGATGTGT
TATGTGCAGAAGCAGCCGGCACCACATTCCCACAGAATGAGCCCTGAGGAGGTCTCTGCACACGATGCCTTAATTTCAAAAGAGAGCAAT
ACACCAAAAATAGATCACTGCTCTTCTCCCTCAAGTTCTGAGGACTCTGGGATCAATGCGATTGGGGCTCACTATGTGGAATCGTGTGAC
GAGGACACAGAAGAAGGAGCAGAACTGAGTTCAGAGGAAGATTACAGTCCAGAGAGCAGCTGGGAACCGGATGAGTGCACCCTTCTCTCC
CCCTCGCAGTCTGACCTGGAAGTGATTGAAACGATAGAAACGACTGTGTGAGAGTCCAGACAGGAAGCCACAGCCTCGGACCCACGCCGA
GCTTTTGTACCTTTGTCTGGTGGATCCTTTTTTCCAATGCTGTTGATATTTTCTACCCACCCCGCCCCGCTCCAACCAACAACCGTAGCA
GTTCAGTGGTATGCTGATTAGCTTCTCTCCGTCTTACAACTAAGACATTCTTTTTATTATAAACAGTTTTCTTTTGTATCCTGACTTACT
TTCTATGTAGCATCTGGTGTCATGAATTGTGACCCCGCCTTAATTTCACTGGGAGATTTGAAGGCGGTGAAGTGATGGTCGCAGAGAATC
TTGGATCAGATTGAGGAGGTACCGAAAGGGAAGGAGCCGGTGTTTTCTCGGTAGCCAGTCCTTCACAGAGACTCTTGCCATTCCCTTTGG
CATGTTCACAGGCACTCCCGTCCTGTCCTGCTTGTCCTACGCAAGTAGCACTCCCTACTGAGTGTGCACTGGTAGATGCCGTTTCTTCCC
TTCCCCTTCTCCCCACACCTGCACTGGGTCTGGATCAGAGCTGCCTCGGCTTACTTCTGGGAGGTCACTGGAGGCCAGCTCAGCCCATGG
TTTGTGGCCAGTGTCTGTACAAGGCTCCGTGACTGGGGCTGAGCTAAACATTCACATGAGAAGAGATGACCTCATCTGTCTCATGCTCAA
TCCAGCCTTAGCTGAGCACCTGTCCCCTGCAGGGGGCTGTGGGGACACAGCATGAATAAGACCTGATTCCCACCATGAAGGGGCCCACAG
TCCTATATATGACACATTCAACTCATGGCACCCAAAAAGCTCTGGGAACCCAGGGGAAGGATGAGGTTTACTTGGCTGGGGCTAGCTGGG
GAATGTGTTTCAGCATTTGAGCTGGCTTCTTGGTGGGTTCCCCAACATTTTTCTGCTTTTAATTGTTCTTCAAGTCTGGGAAAAACTCTT
AGGAAGTTATATAGGTATCACATTTAGGTGGCAGCCACATCTGACATCTTAAGGAAAAAAAATAAATTAATAGTTTTAGTTAGCATGGAA
ATGCTACAGACAGAAGCCCTTTAGGGATTAGGACTGAATCTAATAGGTTTGATTAATTCTGCTTCATTTGGTTGTATGAAGCATTCGTAT
GGTTTAAGTGAGGAATGGATTAGAATTCAGTGTGATGCATGGATTTTTATGCAGCTGCAAAAGCAGTTGAAATAGTTTGCTGCTAAGTCA
GGAGAAAATATCCAGTGTAATAGCCATTCACTTTCCCACACAGTCTGTCTGTTGTATGTGTTCTCTCCCCTCACATGCACAAAATAGTGA
CTAATTCTTTCTTATTTAGCTCTCTTCAGAATTCTACTTCTACTCTCCATTTATACCAGGTATTCTTGTGAGTCAGTTAACTGCTATTTC
TCCAAACCTTCTATCCATGAGGCATAGTTTCAAATCCTGGAAATTTTAAGTATGGCCTAATGAGAACATCAGAGTTGGAGACAGAACAGT
ACTTCCATCCTAACTATCCAGAAGCGCACTCTCAGGCCATTGTGCTCTGAGATTCCCTTGTGCTCTGGCACCATTATGGTACATCTCTAC
GTCACATTAATTTTTTTTTTTTTGAGATGGAGTTTCCCTCTTGCTGCCCAGGCTGGAGTGCAGCGGCGTGATCTTGGCTCTCTACAACCT
CTGCCTCCTGGGGTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTATGGGCACGTGCCACCACACCTGGCTAATTTTTTG
TATTTTTAGTAGAGACGGGCTTTCACCATGTTAGCCAGGATGGTCTCGATCTGACCTTGTGATCCACCCACCTCGGCCTCCCCAAGTGCT
GGGATTACAAGCATGAGCCACCACGCCCGGCCGGATTTGTAAGAAAAAGTTGTGTTCTCCCCTGAAGCCTCCATTTGGCATCATTCACAA
ACTACTCAAGGAAGAATTTGCTTTCCCAGTTGTATGTATAATTTAAGTCGTTTACTAGATAGAACTTTTTTTTAGGTTTAGATGGCCAAG
ACATCTATATGGTTTAGAAGGCAGAGTATACATTTTCCTTTGCAAACAGTATGAGTTAAAACTTTCTATGCTAAATGAGAATGCGGCATA
AAGTCTCCACTTACTGAAATTTAAAGATTCAACAAGACAAACCGAGAAGGGGGTCAGAGGAGCTCTAGGAAAGGCCCAGGAGAGGGCAGT
TGGAGGCAGGTGTGAGCATGAGGAGCTTCCCCCTGCCAGGGCATGGCTCAGGTGGCACAGGGACATCTGATGAACCCTGCCCGAGGTTCT
CGGTGCCTCCCGTGCATGAGTGGCTCACTGAAGGCAGGTGTGGAAGCCAAATGCCTGCAAGCCGTGTGTCAGGCCACAGCAGTGCAGTCA
TGCATCACGCACTCAGGTTTGTAACAGCAACACCAGGGCCCTGTCTAGATTCACCCTGTGGGTGAGCCCGTTCTCCAGATGGGCGTATAA
AGGGGCTTTCTCCTCTACACCGTTCCTGTCAATGTTCCGTACAGGCCCACATTCCCACCACTAAGCCAATGGAGTCAACCAGATTTCTAA
AGCCATGGATATACGTGGTCACGGGGCCACATTTCTGCAGCTGGCTCAGTGGCAGGCTTGGGCCGTCTCTCAGTACCATCTAAGACTTCT
GTCTAGGTTCCTGTTTTTTTAGACTCCTGAACTGCCATTCTGATTAGACACAATTTTAATGGAATTTTTGGATTTAATAATAGTTGATAA
TCACCTTATGTATTTGCACAATCTCTTTATAATTAAAAACTCGCTAAGCTTCACTTGCTACTATCTACTATATAGAATTAGAGACATTCC
ATTGGATTCTAAGCATCAGACACTCCTGGATCTCAAAATGACCTTTTCTAAATAAGCACAAGATTTATTTTTGTCCTAGCACTGTTGATA
ACACTCTGAAATATGTTATTGAACTGGAATTGTTTCTTTATGCTTGCATTCCAAAACCAACTGAAACAGATTGTAGTTTCACTTTAAATT
CTAGGCCTGTTCTATATTATGTGAAGGAATTCTCTGTAACGCTGATACTATGTTGCTAATTTGTGTACTTACAGACACTTTAGAAAATGT
TTAGACTGCAACATGCACTATAACATTGAACTCAGTCACATGAAGTGGTTAACACTTGCACACTGACTGACAGATATGAAAGCTGTATAC
TTTGGACCCAGTAATATGCTCATTGGAGCAAGGGTTGGGCTGTGTGGATGGATAAACTGCTTTCTTGGGTTTACATGGAAACCTGGTACC
ACTCCTACTTTTGGAAAGTTGGTATAAAAGCTATTAGGTAGAAGCTTAATTCCACTAAATGTAGAATTTAGTTTTCTTCTCTAACCAAGA
TTTTAGAAGTTTCAAGTTTCAAATATGCTTATAACTTTTCCAAGAAATGATGATTACAGTGCTTTTGTGGTTACAACTGTTTGGTATATT
AAAAAATAAGGGTTTACTATCACATCTAGGTCTTTTTTACTATGTCATTTTTAAGATATGAAATAAGAATCTGAGGACAGCCCTGAAGAA
CAGTCCTTTCCTGGGAGGGGAAGACTTGTAATTCAAGGTCATACAATACAAAATAAAACAAAAACAAAAGCACCAAGAGCAGAACAAAAC
AACGTAGTTGCTTTCCTGAAATACTTTTTGGATTTGATTCTATCTTGGGAGTGGTGGCTTTACTTTTTTTTTTTTTTTTTTTTTTTTGAG
ACAGAGTCTCGCTCCTTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCCAGCTCTGCCTCCCAGGTTCATGCCATTCTCC
TGCCTCAGCCTCCTGAGTAGCTGGGACTATAGGTGCCCGCCACCATGCCTCGCTAATTTTTTGTATTTTTAGTAGAAACGGGGTTTCACC
GTGTTAGCCAGGATGGTCTTGATCTCATGACCTCGTGATCCACCCTCCTCGGCTTCCCAAAGTGCTGGGATTGCAGGCGTGAACCACCAC
GCCCGGCCGGCTTTACTTCTAATCCTCCACTTCTTGGTCTATTTGAACCATCACAAGTATTTTGGGACCGATAACAAACCCCTTTTATGC
TAATTTAATTCTTGACTTGGGTAATAGGTGCACCTGGATAATTTATAAAGCTGTCCATAGATCTAAGTTTAGTGGTACAGATACTACTGG
GCAGGAGAAAAAGCACAAGTTAAAATATTTCTACAGTCAGCTCTTAATATTCCCACATCTTGTTTGCAAAATTTTATGGTCACGTTCTGG
CTTTTTTACATGAGGAAAACAAAGTTTTAACAGTTTTCTCTTCTGTCCCCTTCTCCAGAGGAGGTGTGAACCAGAACTGAGGAGGCCAGT
TATATTTTAGGCTTTTCAGTAGTACGATTTTGTCCTCTCCCACTGAGGAGGAGGGAAGAAGGGGGAAGCCAGTGGGAGTTCCACACACGT
GGTCAGTGCTGTAAGTTCCCGGATATCAGTGTCTCTCACATCAACACAGAAATAGGGCACTTCTCAACATTAATTTTGGAATTATTCACC
ATTTAAAAATTGTCACTGCTCTTTTTCATTACTGTAGATAACTGAGAGTTAGCTGTTCTAGGAAAAGGCCATGTTTCAGTTAGTGCTATG
ACTTCTTTTTTCGATTAAGGTTGAAGCAGTGTTCTCTTAGTAGCCTGAACACTTCTCAAAGCGACTTATCACTAGCGGCTTTAATATTGA
GCTTCTATATCGTTGTGTCCACCTCACTTTTTAAGGCTGTTCATACCTGGCAATATTCACTTACTCTGCTATTTTTAAAAACTATTTTAA
AGTTTTAAGCACAATGTTGACTCTTCTGTAATTTCCTAAAATTATATTGTTTTCCTACAGACAGCTCAACTTTCCTTGATATGTAACACT

>42502_42502_2_KIDINS220-C3orf70_KIDINS220_chr2_8952525_ENST00000319688_C3orf70_chr3_184801351_ENST00000335012_length(amino acids)=182AA_BP=
MYQPMTPVEQLPSTEIPARPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQPAPHSHRMS
PEEVSAHDALISKESNTPKIDHCSSPSSSEDSGINAIGAHYVESCDEDTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETIET

--------------------------------------------------------------
>42502_42502_3_KIDINS220-C3orf70_KIDINS220_chr2_8952525_ENST00000427284_C3orf70_chr3_184801351_ENST00000335012_length(transcript)=6200nt_BP=686nt
ACGTGATCTGTCAGTTCGCGGAGAGGGAAGAATATGGCCGCCGGGTGTGGTGAGGGCGACGCGCTTGCAGTCGCCGTCTCTTGCTTCCCC
GTCCTCTGACATCGCCTGCAGCCGAGCGGGCCCGTTCCGCCGGAGCTGAGGACCAGGTATTCAAATAAAGTTAATTGCAGCTTTCTGTGA
AAATGTCAGTTTTGATATCACAGAGCGTCATAAATTATGTAGAGGAAGAAAACATTCCTGCTCTGAAAGCTCTTCTTGAAAAATGCAAAG
ATGTAGATGAGAGAAATGAGTGTGGCCAGACTCCACTGATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGA
ATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGGACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAAC
TACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATGGGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAG
TAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTCACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATG
CAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAAGTCAACTGCTCTGATAAGGCAAATACATGTATCAGCCTATGACCCCTGTGGA
ACAGCTTCCAAGCACTGAGATTCCTGCCAGGCCTCGGGAACCCACAAACACCATTCAGATCTCAGTCTCGCTCACCGAACACTTTTTGAA
ATTTGCATCTGTCTTCCAGCCTCCCCTTCCCCCTGACTCACCGAGGTACTGTATGATTTCAGACCTTTTTATTGACAACTATCAGGTTAA
ATGTATTAATGGGAAGATGTGTTATGTGCAGAAGCAGCCGGCACCACATTCCCACAGAATGAGCCCTGAGGAGGTCTCTGCACACGATGC
CTTAATTTCAAAAGAGAGCAATACACCAAAAATAGATCACTGCTCTTCTCCCTCAAGTTCTGAGGACTCTGGGATCAATGCGATTGGGGC
TCACTATGTGGAATCGTGTGACGAGGACACAGAAGAAGGAGCAGAACTGAGTTCAGAGGAAGATTACAGTCCAGAGAGCAGCTGGGAACC
GGATGAGTGCACCCTTCTCTCCCCCTCGCAGTCTGACCTGGAAGTGATTGAAACGATAGAAACGACTGTGTGAGAGTCCAGACAGGAAGC
CACAGCCTCGGACCCACGCCGAGCTTTTGTACCTTTGTCTGGTGGATCCTTTTTTCCAATGCTGTTGATATTTTCTACCCACCCCGCCCC
GCTCCAACCAACAACCGTAGCAGTTCAGTGGTATGCTGATTAGCTTCTCTCCGTCTTACAACTAAGACATTCTTTTTATTATAAACAGTT
TTCTTTTGTATCCTGACTTACTTTCTATGTAGCATCTGGTGTCATGAATTGTGACCCCGCCTTAATTTCACTGGGAGATTTGAAGGCGGT
GAAGTGATGGTCGCAGAGAATCTTGGATCAGATTGAGGAGGTACCGAAAGGGAAGGAGCCGGTGTTTTCTCGGTAGCCAGTCCTTCACAG
AGACTCTTGCCATTCCCTTTGGCATGTTCACAGGCACTCCCGTCCTGTCCTGCTTGTCCTACGCAAGTAGCACTCCCTACTGAGTGTGCA
CTGGTAGATGCCGTTTCTTCCCTTCCCCTTCTCCCCACACCTGCACTGGGTCTGGATCAGAGCTGCCTCGGCTTACTTCTGGGAGGTCAC
TGGAGGCCAGCTCAGCCCATGGTTTGTGGCCAGTGTCTGTACAAGGCTCCGTGACTGGGGCTGAGCTAAACATTCACATGAGAAGAGATG
ACCTCATCTGTCTCATGCTCAATCCAGCCTTAGCTGAGCACCTGTCCCCTGCAGGGGGCTGTGGGGACACAGCATGAATAAGACCTGATT
CCCACCATGAAGGGGCCCACAGTCCTATATATGACACATTCAACTCATGGCACCCAAAAAGCTCTGGGAACCCAGGGGAAGGATGAGGTT
TACTTGGCTGGGGCTAGCTGGGGAATGTGTTTCAGCATTTGAGCTGGCTTCTTGGTGGGTTCCCCAACATTTTTCTGCTTTTAATTGTTC
TTCAAGTCTGGGAAAAACTCTTAGGAAGTTATATAGGTATCACATTTAGGTGGCAGCCACATCTGACATCTTAAGGAAAAAAAATAAATT
AATAGTTTTAGTTAGCATGGAAATGCTACAGACAGAAGCCCTTTAGGGATTAGGACTGAATCTAATAGGTTTGATTAATTCTGCTTCATT
TGGTTGTATGAAGCATTCGTATGGTTTAAGTGAGGAATGGATTAGAATTCAGTGTGATGCATGGATTTTTATGCAGCTGCAAAAGCAGTT
GAAATAGTTTGCTGCTAAGTCAGGAGAAAATATCCAGTGTAATAGCCATTCACTTTCCCACACAGTCTGTCTGTTGTATGTGTTCTCTCC
CCTCACATGCACAAAATAGTGACTAATTCTTTCTTATTTAGCTCTCTTCAGAATTCTACTTCTACTCTCCATTTATACCAGGTATTCTTG
TGAGTCAGTTAACTGCTATTTCTCCAAACCTTCTATCCATGAGGCATAGTTTCAAATCCTGGAAATTTTAAGTATGGCCTAATGAGAACA
TCAGAGTTGGAGACAGAACAGTACTTCCATCCTAACTATCCAGAAGCGCACTCTCAGGCCATTGTGCTCTGAGATTCCCTTGTGCTCTGG
CACCATTATGGTACATCTCTACGTCACATTAATTTTTTTTTTTTTGAGATGGAGTTTCCCTCTTGCTGCCCAGGCTGGAGTGCAGCGGCG
TGATCTTGGCTCTCTACAACCTCTGCCTCCTGGGGTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTATGGGCACGTGCC
ACCACACCTGGCTAATTTTTTGTATTTTTAGTAGAGACGGGCTTTCACCATGTTAGCCAGGATGGTCTCGATCTGACCTTGTGATCCACC
CACCTCGGCCTCCCCAAGTGCTGGGATTACAAGCATGAGCCACCACGCCCGGCCGGATTTGTAAGAAAAAGTTGTGTTCTCCCCTGAAGC
CTCCATTTGGCATCATTCACAAACTACTCAAGGAAGAATTTGCTTTCCCAGTTGTATGTATAATTTAAGTCGTTTACTAGATAGAACTTT
TTTTTAGGTTTAGATGGCCAAGACATCTATATGGTTTAGAAGGCAGAGTATACATTTTCCTTTGCAAACAGTATGAGTTAAAACTTTCTA
TGCTAAATGAGAATGCGGCATAAAGTCTCCACTTACTGAAATTTAAAGATTCAACAAGACAAACCGAGAAGGGGGTCAGAGGAGCTCTAG
GAAAGGCCCAGGAGAGGGCAGTTGGAGGCAGGTGTGAGCATGAGGAGCTTCCCCCTGCCAGGGCATGGCTCAGGTGGCACAGGGACATCT
GATGAACCCTGCCCGAGGTTCTCGGTGCCTCCCGTGCATGAGTGGCTCACTGAAGGCAGGTGTGGAAGCCAAATGCCTGCAAGCCGTGTG
TCAGGCCACAGCAGTGCAGTCATGCATCACGCACTCAGGTTTGTAACAGCAACACCAGGGCCCTGTCTAGATTCACCCTGTGGGTGAGCC
CGTTCTCCAGATGGGCGTATAAAGGGGCTTTCTCCTCTACACCGTTCCTGTCAATGTTCCGTACAGGCCCACATTCCCACCACTAAGCCA
ATGGAGTCAACCAGATTTCTAAAGCCATGGATATACGTGGTCACGGGGCCACATTTCTGCAGCTGGCTCAGTGGCAGGCTTGGGCCGTCT
CTCAGTACCATCTAAGACTTCTGTCTAGGTTCCTGTTTTTTTAGACTCCTGAACTGCCATTCTGATTAGACACAATTTTAATGGAATTTT
TGGATTTAATAATAGTTGATAATCACCTTATGTATTTGCACAATCTCTTTATAATTAAAAACTCGCTAAGCTTCACTTGCTACTATCTAC
TATATAGAATTAGAGACATTCCATTGGATTCTAAGCATCAGACACTCCTGGATCTCAAAATGACCTTTTCTAAATAAGCACAAGATTTAT
TTTTGTCCTAGCACTGTTGATAACACTCTGAAATATGTTATTGAACTGGAATTGTTTCTTTATGCTTGCATTCCAAAACCAACTGAAACA
GATTGTAGTTTCACTTTAAATTCTAGGCCTGTTCTATATTATGTGAAGGAATTCTCTGTAACGCTGATACTATGTTGCTAATTTGTGTAC
TTACAGACACTTTAGAAAATGTTTAGACTGCAACATGCACTATAACATTGAACTCAGTCACATGAAGTGGTTAACACTTGCACACTGACT
GACAGATATGAAAGCTGTATACTTTGGACCCAGTAATATGCTCATTGGAGCAAGGGTTGGGCTGTGTGGATGGATAAACTGCTTTCTTGG
GTTTACATGGAAACCTGGTACCACTCCTACTTTTGGAAAGTTGGTATAAAAGCTATTAGGTAGAAGCTTAATTCCACTAAATGTAGAATT
TAGTTTTCTTCTCTAACCAAGATTTTAGAAGTTTCAAGTTTCAAATATGCTTATAACTTTTCCAAGAAATGATGATTACAGTGCTTTTGT
GGTTACAACTGTTTGGTATATTAAAAAATAAGGGTTTACTATCACATCTAGGTCTTTTTTACTATGTCATTTTTAAGATATGAAATAAGA
ATCTGAGGACAGCCCTGAAGAACAGTCCTTTCCTGGGAGGGGAAGACTTGTAATTCAAGGTCATACAATACAAAATAAAACAAAAACAAA
AGCACCAAGAGCAGAACAAAACAACGTAGTTGCTTTCCTGAAATACTTTTTGGATTTGATTCTATCTTGGGAGTGGTGGCTTTACTTTTT
TTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCGCTCCTTCACCCAGGCTGGAGTGCAGTGGCGCGATCTCGGCTCACTGCCAGCTCTGCC
TCCCAGGTTCATGCCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTATAGGTGCCCGCCACCATGCCTCGCTAATTTTTTGTATTT
TTAGTAGAAACGGGGTTTCACCGTGTTAGCCAGGATGGTCTTGATCTCATGACCTCGTGATCCACCCTCCTCGGCTTCCCAAAGTGCTGG
GATTGCAGGCGTGAACCACCACGCCCGGCCGGCTTTACTTCTAATCCTCCACTTCTTGGTCTATTTGAACCATCACAAGTATTTTGGGAC
CGATAACAAACCCCTTTTATGCTAATTTAATTCTTGACTTGGGTAATAGGTGCACCTGGATAATTTATAAAGCTGTCCATAGATCTAAGT
TTAGTGGTACAGATACTACTGGGCAGGAGAAAAAGCACAAGTTAAAATATTTCTACAGTCAGCTCTTAATATTCCCACATCTTGTTTGCA
AAATTTTATGGTCACGTTCTGGCTTTTTTACATGAGGAAAACAAAGTTTTAACAGTTTTCTCTTCTGTCCCCTTCTCCAGAGGAGGTGTG
AACCAGAACTGAGGAGGCCAGTTATATTTTAGGCTTTTCAGTAGTACGATTTTGTCCTCTCCCACTGAGGAGGAGGGAAGAAGGGGGAAG
CCAGTGGGAGTTCCACACACGTGGTCAGTGCTGTAAGTTCCCGGATATCAGTGTCTCTCACATCAACACAGAAATAGGGCACTTCTCAAC
ATTAATTTTGGAATTATTCACCATTTAAAAATTGTCACTGCTCTTTTTCATTACTGTAGATAACTGAGAGTTAGCTGTTCTAGGAAAAGG
CCATGTTTCAGTTAGTGCTATGACTTCTTTTTTCGATTAAGGTTGAAGCAGTGTTCTCTTAGTAGCCTGAACACTTCTCAAAGCGACTTA
TCACTAGCGGCTTTAATATTGAGCTTCTATATCGTTGTGTCCACCTCACTTTTTAAGGCTGTTCATACCTGGCAATATTCACTTACTCTG
CTATTTTTAAAAACTATTTTAAAGTTTTAAGCACAATGTTGACTCTTCTGTAATTTCCTAAAATTATATTGTTTTCCTACAGACAGCTCA

>42502_42502_3_KIDINS220-C3orf70_KIDINS220_chr2_8952525_ENST00000427284_C3orf70_chr3_184801351_ENST00000335012_length(amino acids)=182AA_BP=
MYQPMTPVEQLPSTEIPARPREPTNTIQISVSLTEHFLKFASVFQPPLPPDSPRYCMISDLFIDNYQVKCINGKMCYVQKQPAPHSHRMS
PEEVSAHDALISKESNTPKIDHCSSPSSSEDSGINAIGAHYVESCDEDTEEGAELSSEEDYSPESSWEPDECTLLSPSQSDLEVIETIET

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Fusion Gene PPI Analysis for KIDINS220-C3orf70

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for KIDINS220-C3orf70

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for KIDINS220-C3orf70

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source