FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:KIDINS220-SOX7 (FusionGDB2 ID:42514)

Fusion Gene Summary for KIDINS220-SOX7

check button Fusion gene summary
Fusion gene informationFusion gene name: KIDINS220-SOX7
Fusion gene ID: 42514
HgeneTgene
Gene symbol

KIDINS220

SOX7

Gene ID

57498

83595

Gene namekinase D interacting substrate 220SRY-box transcription factor 7
SynonymsARMS|SINO-
Cytomap

2p25.1

8p23.1

Type of geneprotein-codingprotein-coding
Descriptionkinase D-interacting substrate of 220 kDaankyrin repeat-rich membrane-spanning proteinkinase D-interacting substrate 220kDatranscription factor SOX-7SRY (sex determining region Y)-box 7SRY-box 7
Modification date2020031320200313
UniProtAcc

Q9ULH0

.
Ensembl transtripts involved in fusion geneENST00000256707, ENST00000418530, 
ENST00000427284, ENST00000473731, 
ENST00000319688, ENST00000436566, 
ENST00000304501, ENST00000553390, 
ENST00000554914, 
Fusion gene scores* DoF score13 X 11 X 9=12875 X 5 X 3=75
# samples 115
** MAII scorelog2(11/1287*10)=-3.54843662469604
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(5/75*10)=-0.584962500721156
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KIDINS220 [Title/Abstract] AND SOX7 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKIDINS220(8890242)-SOX7(10692285), # samples:1
Anticipated loss of major functional domain due to fusion event.KIDINS220-SOX7 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
KIDINS220-SOX7 seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.
KIDINS220-SOX7 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneSOX7

GO:0001706

endoderm formation

18682240

TgeneSOX7

GO:0008285

negative regulation of cell proliferation

19108950

TgeneSOX7

GO:0043280

positive regulation of cysteine-type endopeptidase activity involved in apoptotic process

19108950

TgeneSOX7

GO:0045892

negative regulation of transcription, DNA-templated

19108950

TgeneSOX7

GO:0060828

regulation of canonical Wnt signaling pathway

19108950


check buttonFusion gene breakpoints across KIDINS220 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SOX7 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4SARCTCGA-X6-A8C6-01AKIDINS220chr2

8890242

-SOX7chr8

10692285

-


Top

Fusion Gene ORF analysis for KIDINS220-SOX7

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000256707ENST00000304501KIDINS220chr2

8890242

-SOX7chr8

10692285

-
5CDS-intronENST00000418530ENST00000304501KIDINS220chr2

8890242

-SOX7chr8

10692285

-
5CDS-intronENST00000427284ENST00000304501KIDINS220chr2

8890242

-SOX7chr8

10692285

-
5CDS-intronENST00000473731ENST00000304501KIDINS220chr2

8890242

-SOX7chr8

10692285

-
Frame-shiftENST00000256707ENST00000553390KIDINS220chr2

8890242

-SOX7chr8

10692285

-
Frame-shiftENST00000256707ENST00000554914KIDINS220chr2

8890242

-SOX7chr8

10692285

-
Frame-shiftENST00000427284ENST00000553390KIDINS220chr2

8890242

-SOX7chr8

10692285

-
Frame-shiftENST00000427284ENST00000554914KIDINS220chr2

8890242

-SOX7chr8

10692285

-
Frame-shiftENST00000473731ENST00000553390KIDINS220chr2

8890242

-SOX7chr8

10692285

-
Frame-shiftENST00000473731ENST00000554914KIDINS220chr2

8890242

-SOX7chr8

10692285

-
In-frameENST00000418530ENST00000553390KIDINS220chr2

8890242

-SOX7chr8

10692285

-
In-frameENST00000418530ENST00000554914KIDINS220chr2

8890242

-SOX7chr8

10692285

-
intron-3CDSENST00000319688ENST00000553390KIDINS220chr2

8890242

-SOX7chr8

10692285

-
intron-3CDSENST00000319688ENST00000554914KIDINS220chr2

8890242

-SOX7chr8

10692285

-
intron-3CDSENST00000436566ENST00000553390KIDINS220chr2

8890242

-SOX7chr8

10692285

-
intron-3CDSENST00000436566ENST00000554914KIDINS220chr2

8890242

-SOX7chr8

10692285

-
intron-intronENST00000319688ENST00000304501KIDINS220chr2

8890242

-SOX7chr8

10692285

-
intron-intronENST00000436566ENST00000304501KIDINS220chr2

8890242

-SOX7chr8

10692285

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000418530KIDINS220chr28890242-ENST00000554914SOX7chr810692285-5239359616436791171
ENST00000418530KIDINS220chr28890242-ENST00000553390SOX7chr810692285-5239359616436791171

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000418530ENST00000554914KIDINS220chr28890242-SOX7chr810692285-0.0002798870.99972004
ENST00000418530ENST00000553390KIDINS220chr28890242-SOX7chr810692285-0.0002798870.99972004

Top

Fusion Genomic Features for KIDINS220-SOX7


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for KIDINS220-SOX7


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:8890242/chr8:10692285)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KIDINS220

Q9ULH0

.
FUNCTION: Promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in neurotrophin- and ephrin-mediated neuronal outgrowth and in axon guidance during neural development and in neuronal regeneration (By similarity). Modulates stress-induced apoptosis of melanoma cells via regulation of the MEK/ERK signaling pathway. {ECO:0000250, ECO:0000269|PubMed:18089783}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430440_95311381772.0DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428440_95310961673.0DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429440_95311381753.0DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429440_95311381753.0DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430103_13211381772.0RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430136_16511381772.0RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430169_19811381772.0RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430202_23111381772.0RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430235_26411381772.0RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430268_29711381772.0RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430301_33011381772.0RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430334_36311381772.0RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430367_39611381772.0RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-243037_6611381772.0RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-24304_3311381772.0RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-243070_9911381772.0RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428103_13210961673.0RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428136_16510961673.0RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428169_19810961673.0RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428202_23110961673.0RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428235_26410961673.0RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428268_29710961673.0RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428301_33010961673.0RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428334_36310961673.0RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428367_39610961673.0RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-242837_6610961673.0RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-24284_3310961673.0RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-242870_9910961673.0RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429103_13211381753.0RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429136_16511381753.0RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429169_19811381753.0RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429202_23111381753.0RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429235_26411381753.0RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429268_29711381753.0RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429301_33011381753.0RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429334_36311381753.0RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429367_39611381753.0RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-242937_6611381753.0RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-24294_3311381753.0RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-242970_9911381753.0RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429103_13211381753.0RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429136_16511381753.0RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429169_19811381753.0RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429202_23111381753.0RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429235_26411381753.0RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429268_29711381753.0RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429301_33011381753.0RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429334_36311381753.0RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429367_39611381753.0RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-242937_6611381753.0RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-24294_3311381753.0RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-242970_9911381753.0RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-24301_49911381772.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430521_52411381772.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430546_65911381772.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430681_68511381772.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-24281_49910961673.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428521_52410961673.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428546_65910961673.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428681_68510961673.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-24291_49911381753.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429521_52411381753.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429546_65911381753.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429681_68511381753.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-24291_49911381753.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429521_52411381753.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429546_65911381753.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429681_68511381753.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430500_52011381772.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430525_54511381772.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430660_68011381772.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430686_70611381772.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428500_52010961673.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428525_54510961673.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428660_68010961673.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428686_70610961673.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429500_52011381753.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429525_54511381753.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429660_68011381753.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429686_70611381753.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429500_52011381753.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429525_54511381753.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429660_68011381753.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429686_70611381753.0TransmembraneHelical
TgeneSOX7chr2:8890242chr8:10692285ENST000003045010245_1130389.0DNA bindingHMG box
TgeneSOX7chr2:8890242chr8:10692285ENST0000030450102268_3880389.0DomainSox C-terminal

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123440_95301032.0DomainNote=KAP NTPase
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-24301766_177111381772.0MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-1231766_177101032.0MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-24281766_177110961673.0MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-24291766_177111381753.0MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-24291766_177111381753.0MotifPDZ-binding
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123103_13201032.0RepeatNote=ANK 4
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123136_16501032.0RepeatNote=ANK 5
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123169_19801032.0RepeatNote=ANK 6
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123202_23101032.0RepeatNote=ANK 7
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123235_26401032.0RepeatNote=ANK 8
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123268_29701032.0RepeatNote=ANK 9
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123301_33001032.0RepeatNote=ANK 10
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123334_36301032.0RepeatNote=ANK 11
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123367_39601032.0RepeatNote=ANK 12
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-12337_6601032.0RepeatNote=ANK 2
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-1234_3301032.0RepeatNote=ANK 1
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-12370_9901032.0RepeatNote=ANK 3
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000256707-2430707_177111381772.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-1231_49901032.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123521_52401032.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123546_65901032.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123681_68501032.0Topological domainExtracellular
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123707_177101032.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000418530-2428707_177110961673.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000427284-2429707_177111381753.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000473731-2429707_177111381753.0Topological domainCytoplasmic
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123500_52001032.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123525_54501032.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123660_68001032.0TransmembraneHelical
HgeneKIDINS220chr2:8890242chr8:10692285ENST00000319688-123686_70601032.0TransmembraneHelical


Top

Fusion Gene Sequence for KIDINS220-SOX7


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42514_42514_1_KIDINS220-SOX7_KIDINS220_chr2_8890242_ENST00000418530_SOX7_chr8_10692285_ENST00000553390_length(transcript)=5239nt_BP=3596nt
ACGTGATCTGTCAGTTCGCGGAGAGGGAAGAATATGGCCGCCGGGTGTGGTGAGGGCGACGCGCTTGCAGTCGCCGTCTCTTGCTTCCCC
GTCCTCTGACATCGCCTGCAGCCGAGCGGGCCCGTTCCGCCGGAGCTGAGGACCAGGTATTCAAATAAAGTTAATTGCAGCTTTCTGTGA
AAATGTCAGTTTTGATATCACAGAGCGTCATAAATTATGTAGAGGAAGAAAACATTCCTGCTCTGAAAGCTCTTCTTGAAAAATGCAAAG
ATGTAGATGAGAGAAATGAGTGTGGCCAGACTCCACTGATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGA
ATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGGACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAAC
TACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATGGGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAG
TAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTCACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATG
CAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAAGTCAACTGCTCTGATAAGTATGGAACCACCCCTTTAGTTTGGGCTGCACGAA
AGGGTCATTTGGAATGTGTGAAACATTTATTGGCCATGGGAGCTGATGTGGATCAAGAAGGAGCTAATTCAATGACTGCACTTATTGTGG
CAGTGAAAGGAGGTTACACACAGTCAGTAAAAGAAATTTTGAAGAGGAATCCAAATGTAAACTTAACAGATAAAGATGGAAATACAGCTT
TGATGATTGCATCAAAGGAGGGACATACGGAGATTGTGCAGGATCTGCTCGACGCTGGAACATATGTGAACATACCTGACAGGAGTGGGG
ATACTGTGTTGATTGGCGCTGTCAGAGGTGGTCATGTTGAAATTGTTCGAGCGCTTCTCCAAAAATATGCTGATATAGACATTAGAGGAC
AGGATAATAAAACTGCTTTGTATTGGGCTGTTGAGAAAGGAAATGCAACAATGGTGAGAGATATCTTACAGTGCAATCCTGACACTGAAA
TATGCACAAAGGATGGTGAAACGCCACTTATAAAGGCTACCAAGATGAGAAACATTGAAGTGGTGGAGCTGCTGCTAGATAAAGGTGCTA
AAGTGTCTGCTGTAGATAAGAAAGGAGATACTCCCTTGCATATTGCTATTCGTGGAAGGAGCCGGAAACTGGCAGAACTGCTTTTAAGAA
ATCCCAAAGATGGGCGATTACTTTATAGGCCCAACAAAGCAGGCGAGACTCCTTATAATATTGACTGTAGCCATCAGAAGAGTATTTTAA
CTCAAATATTTGGAGCCAGACACTTGTCTCCTACTGAAACAGACGGTGACATGCTTGGATATGATTTATATAGCAGTGCCCTGGCAGATA
TTCTCAGTGAGCCTACCATGCAGCCACCCATTTGTGTGGGGTTATATGCACAGTGGGGAAGTGGGAAATCTTTCTTACTCAAGAAACTAG
AAGACGAAATGAAAACCTTCGCCGGACAACAGATTGAGCCTCTCTTTCAGTTCTCATGGCTCATAGTGTTTCTTACCCTGCTACTTTGTG
GAGGGCTTGGTTTATTGTTTGCCTTCACGGTCCACCCAAATCTTGGAATAGCAGTGTCACTGAGCTTCTTGGCTCTCTTATATATATTCT
TTATTGTCATTTACTTTGGTGGACGAAGAGAAGGAGAGAGTTGGAATTGGGCCTGGGTCCTCAGCACTAGATTGGCAAGACATATTGGAT
ATTTGGAACTCCTCCTTAAATTGATGTTTGTGAATCCACCTGAGTTGCCAGAGCAGACTACTAAAGCTTTACCTGTGAGGTTTTTGTTTA
CAGATTACAATAGACTGTCCAGTGTAGGTGGAGAAACTTCTCTGGCTGAAATGATTGCAACCCTCTCGGATGCTTGTGAAAGAGAGTTTG
GCTTTTTGGCAACCAGGCTTTTTCGAGTATTCAAGACTGAAGATACTCAGGGTAAAAAGAAATGGAAAAAAACATGTTGTCTCCCATCTT
TTGTCATCTTCCTTTTTATCATTGGCTGCATTATATCTGGAATTACTCTTCTGGCTATATTTAGAGTTGACCCAAAGCATCTGACTGTAA
ATGCTGTCCTCATATCAATCGCATCTGTAGTGGGATTGGCCTTTGTGTTGAACTGTCGTACATGGTGGCAAGTGCTGGACTCGCTCCTGA
ATTCCCAAAGAAAACGCCTCCATAATGCAGCCTCCAAACTGCACAAATTGAAAAGTGAAGGATTCATGAAAGTTCTTAAATGTGAAGTGG
AATTGATGGCCAGGATGGCAAAAACCATTGACAGCTTCACTCAGAATCAGACAAGGCTGGTGGTCATCATCGATGGATTAGATGCCTGTG
AGCAGGACAAAGTCCTTCAGATGCTGGACACTGTCCGAGTTCTGTTTTCAAAAGGCCCGTTCATTGCCATTTTTGCAAGTGATCCACATA
TTATCATAAAGGCAATTAACCAGAACCTCAATAGTGTGCTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCACT
TGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCAAGAAAATTTCTCGTAACTTCAGCAACAAATGGAGACGTTCCATGCTCAGATA
CTACAGGGATACAGGAAGATGCTGACAGAAGAGTTTCACAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAATA
GACGGGACACTTACCGAAGAAGGCAGATGCAGAGGACCATCACTCGCCAGATGTCCTTTGATCTTACAAAACTGCTGGTTACCGAGGACT
GGTTCAGTGACATCAGTCCCCAGACCATGAGAAGATTACTTAATATTGTTTCTGTGACAGGACGATTACTGAGAGCCAATCAGATTAGTT
TCAACTGGGACAGGCTTGCTAGCTGGATCAACCTTACTGAGCAGTGGCCATACCGGACTTCATGGCTCATATTATATTTGGAAGAGACTG
AAGGTATTCCAGATCAAATGACATTAAAAACCATCTACGAAAGAATATCAAAGAATATTCCAACAACTAAGGATGTTGAGCCACTTCTTG
AAATTGATGGAGATATAAGAAATTTTGAAGTGTTTTTGTCTTCAAGGACCCCAGTTCTTGTGGCTCGAGATGTAAAAGTCTTTTTGCCAT
GCACTGTAAACCTAGATCCCAAACTACGGGAAATTATTGCAGATGTTCGTGCTGCCAGAGAGCAGATCAGTATTGGAGGACTGGCGTACC
CCCCGCTCCCTCTACATGAGGGTCCTCCTAGGGCGCCATCAGGGTACAGCCAGCCCCCATCCGTGTGCTCTTCCACGTCCTTCAATGGGC
CCTTCGCAGGTGGAGTGGTGTCACCACAGCCTCACAGCAGCTATTACAGCGGCATGACGGGCCCTCAGCATCCCTTCTACAACAGGGTCG
GCGGAAGCAGAAGTGGGCTGTGGATCCTCAGAACACTGCCTGGAGTAATGACGATTCCAAGTTTGGCCAGCGGATGCTAGAGAAGATGGG
GTGGTCTAAAGGAAAGGGTTTAGGGGCTCAGGAGCAAGGAGCCACAGATCATATTAAAGTTCAAGTGAAAAATAACCACCTGGGACTCGG
AGCTACCATCAATAATGAAGACAACTGGATTGCCCATCAGGATGATTTTAACCAGCTTCTGGCCGAACTGAACACTTGCCATGGGCAGGA
AACCACAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCGTGTTCACTATATGAA
ATTCACAAAAGGAAAGTCGTGGAAGGCGCTGACGCTGTCCCAGAAGAGGCCGTACGTGGACGAGGCGGAGCGGCTGCGCCTGCAGCACAT
GCAGGACTACCCCAACTACAAGTACCGGCCGCGCAGGAAGAAGCAGGCCAAGCGGCTGTGCAAGCGCGTGGACCCGGGCTTCCTTCTGAG
CTCCCTCTCCCGGGACCAGAACGCCCTGCCGGAGAAGAGAAGCGGCAGCCGGGGGGCGCTGGGGGAGAAGGAGGACAGGGGTGAGTACTC
CCCCGGCACTGCCCTGCCCAGCCTCCGGGGCTGCTACCACGAGGGGCCGGCTGGTGGTGGCGGCGGCGGCACCCCGAGCAGTGTGGACAC
GTACCCGTACGGGCTGCCCACACCTCCTGAAATGTCTCCCCTGGACGTGCTGGAGCCGGAGCAGACCTTCTTCTCCTCCCCCTGCCAGGA
GGAGCATGGCCATCCCCGCCGCATCCCCCACCTGCCAGGGCACCCGTACTCACCGGAGTACGCCCCAAGCCCTCTCCACTGTAGCCACCC
CCTGGGCTCCCTGGCCCTTGGCCAGTCCCCCGGCGTCTCCATGATGTCCCCTGTACCCGGCTGTCCCCCATCTCCTGCCTATTACTCCCC
GGCCACCTACCACCCACTCCACTCCAACCTCCAAGCCCACCTGGGCCAGCTTTCCCCGCCTCCTGAGCACCCTGGCTTCGACGCCCTGGA
TCAACTGAGCCAGGTGGAACTCCTGGGGGACATGGATCGCAATGAATTCGACCAGTATTTGAACACTCCTGGCCACCCAGACTCCGCCAC
AGGGGCCATGGCCCTCAGTGGGCATGTTCCGGTCTCCCAGGTGACACCAACGGGTCCCACAGAGACCAGCCTCATCTCCGTCCTGGCTGA
TGCCACGGCCACGTACTACAACAGCTACAGTGTGTCATAGAGCTGGAGGCGCCCCGTCCGGTCAGCCCTCGCGCCCTCTCCTTCTTGTGC
CTTGAGTGGCAGAGGAGCCGTCCAGCCACACCAGCTTTCCTCCCACCGCTCAGGGCAGGGAGGTCTGAACTGCGGCCCCAGAGCCTTTGG
CCTAAGCTGGACTCTCCTTATCCGAGTGCCGCCTCTATCCCCTTCCCCACGTTCCAGCCCCTGCAGCCCACATTTTAAGTATATTCCTTC
AAGTGAGTTTTCCTCCAGCCCCTGAGAGTTGCTGTCTCCCAGTGGAATGTTCACTGACGTCTTTTCTTGGTAGCCATCATCGAAACTAAT

>42514_42514_1_KIDINS220-SOX7_KIDINS220_chr2_8890242_ENST00000418530_SOX7_chr8_10692285_ENST00000553390_length(amino acids)=1171AA_BP=1144
MQLSVKMSVLISQSVINYVEEENIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHV
HIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPL
VWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNI
PDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELL
LDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNIDCSHQKSILTQIFGARHLSPTETDGDMLGYDLYS
SALADILSEPTMQPPICVGLYAQWGSGKSFLLKKLEDEMKTFAGQQIEPLFQFSWLIVFLTLLLCGGLGLLFAFTVHPNLGIAVSLSFLA
LLYIFFIVIYFGGRREGESWNWAWVLSTRLARHIGYLELLLKLMFVNPPELPEQTTKALPVRFLFTDYNRLSSVGGETSLAEMIATLSDA
CEREFGFLATRLFRVFKTEDTQGKKKWKKTCCLPSFVIFLFIIGCIISGITLLAIFRVDPKHLTVNAVLISIASVVGLAFVLNCRTWWQV
LDSLLNSQRKRLHNAASKLHKLKSEGFMKVLKCEVELMARMAKTIDSFTQNQTRLVVIIDGLDACEQDKVLQMLDTVRVLFSKGPFIAIF
ASDPHIIIKAINQNLNSVLRDSNINGHDYMRNIVHLPVFLNSRGLSNARKFLVTSATNGDVPCSDTTGIQEDADRRVSQNSLGEMTKLGS
KTALNRRDTYRRRQMQRTITRQMSFDLTKLLVTEDWFSDISPQTMRRLLNIVSVTGRLLRANQISFNWDRLASWINLTEQWPYRTSWLIL
YLEETEGIPDQMTLKTIYERISKNIPTTKDVEPLLEIDGDIRNFEVFLSSRTPVLVARDVKVFLPCTVNLDPKLREIIADVRAAREQISI
GGLAYPPLPLHEGPPRAPSGYSQPPSVCSSTSFNGPFAGGVVSPQPHSSYYSGMTGPQHPFYNRVGGSRSGLWILRTLPGVMTIPSLASG

--------------------------------------------------------------
>42514_42514_2_KIDINS220-SOX7_KIDINS220_chr2_8890242_ENST00000418530_SOX7_chr8_10692285_ENST00000554914_length(transcript)=5239nt_BP=3596nt
ACGTGATCTGTCAGTTCGCGGAGAGGGAAGAATATGGCCGCCGGGTGTGGTGAGGGCGACGCGCTTGCAGTCGCCGTCTCTTGCTTCCCC
GTCCTCTGACATCGCCTGCAGCCGAGCGGGCCCGTTCCGCCGGAGCTGAGGACCAGGTATTCAAATAAAGTTAATTGCAGCTTTCTGTGA
AAATGTCAGTTTTGATATCACAGAGCGTCATAAATTATGTAGAGGAAGAAAACATTCCTGCTCTGAAAGCTCTTCTTGAAAAATGCAAAG
ATGTAGATGAGAGAAATGAGTGTGGCCAGACTCCACTGATGATAGCTGCCGAACAAGGCAATCTGGAAATAGTGAAGGAATTAATTAAGA
ATGGAGCTAACTGCAATCTGGAAGATTTGGATAATTGGACAGCACTTATATCTGCATCGAAAGAAGGGCATGTGCACATCGTAGAGGAAC
TACTGAAATGTGGGGTTAACTTGGAGCACCGTGATATGGGAGGATGGACAGCTCTTATGTGGGCATGTTACAAAGGCCGTACTGACGTAG
TAGAGTTGCTTCTTTCTCATGGTGCCAATCCAAGTGTCACTGGTCTGTACAGTGTTTACCCAATCATTTGGGCAGCAGGGAGAGGCCATG
CAGATATAGTTCATCTTTTACTGCAAAATGGTGCTAAAGTCAACTGCTCTGATAAGTATGGAACCACCCCTTTAGTTTGGGCTGCACGAA
AGGGTCATTTGGAATGTGTGAAACATTTATTGGCCATGGGAGCTGATGTGGATCAAGAAGGAGCTAATTCAATGACTGCACTTATTGTGG
CAGTGAAAGGAGGTTACACACAGTCAGTAAAAGAAATTTTGAAGAGGAATCCAAATGTAAACTTAACAGATAAAGATGGAAATACAGCTT
TGATGATTGCATCAAAGGAGGGACATACGGAGATTGTGCAGGATCTGCTCGACGCTGGAACATATGTGAACATACCTGACAGGAGTGGGG
ATACTGTGTTGATTGGCGCTGTCAGAGGTGGTCATGTTGAAATTGTTCGAGCGCTTCTCCAAAAATATGCTGATATAGACATTAGAGGAC
AGGATAATAAAACTGCTTTGTATTGGGCTGTTGAGAAAGGAAATGCAACAATGGTGAGAGATATCTTACAGTGCAATCCTGACACTGAAA
TATGCACAAAGGATGGTGAAACGCCACTTATAAAGGCTACCAAGATGAGAAACATTGAAGTGGTGGAGCTGCTGCTAGATAAAGGTGCTA
AAGTGTCTGCTGTAGATAAGAAAGGAGATACTCCCTTGCATATTGCTATTCGTGGAAGGAGCCGGAAACTGGCAGAACTGCTTTTAAGAA
ATCCCAAAGATGGGCGATTACTTTATAGGCCCAACAAAGCAGGCGAGACTCCTTATAATATTGACTGTAGCCATCAGAAGAGTATTTTAA
CTCAAATATTTGGAGCCAGACACTTGTCTCCTACTGAAACAGACGGTGACATGCTTGGATATGATTTATATAGCAGTGCCCTGGCAGATA
TTCTCAGTGAGCCTACCATGCAGCCACCCATTTGTGTGGGGTTATATGCACAGTGGGGAAGTGGGAAATCTTTCTTACTCAAGAAACTAG
AAGACGAAATGAAAACCTTCGCCGGACAACAGATTGAGCCTCTCTTTCAGTTCTCATGGCTCATAGTGTTTCTTACCCTGCTACTTTGTG
GAGGGCTTGGTTTATTGTTTGCCTTCACGGTCCACCCAAATCTTGGAATAGCAGTGTCACTGAGCTTCTTGGCTCTCTTATATATATTCT
TTATTGTCATTTACTTTGGTGGACGAAGAGAAGGAGAGAGTTGGAATTGGGCCTGGGTCCTCAGCACTAGATTGGCAAGACATATTGGAT
ATTTGGAACTCCTCCTTAAATTGATGTTTGTGAATCCACCTGAGTTGCCAGAGCAGACTACTAAAGCTTTACCTGTGAGGTTTTTGTTTA
CAGATTACAATAGACTGTCCAGTGTAGGTGGAGAAACTTCTCTGGCTGAAATGATTGCAACCCTCTCGGATGCTTGTGAAAGAGAGTTTG
GCTTTTTGGCAACCAGGCTTTTTCGAGTATTCAAGACTGAAGATACTCAGGGTAAAAAGAAATGGAAAAAAACATGTTGTCTCCCATCTT
TTGTCATCTTCCTTTTTATCATTGGCTGCATTATATCTGGAATTACTCTTCTGGCTATATTTAGAGTTGACCCAAAGCATCTGACTGTAA
ATGCTGTCCTCATATCAATCGCATCTGTAGTGGGATTGGCCTTTGTGTTGAACTGTCGTACATGGTGGCAAGTGCTGGACTCGCTCCTGA
ATTCCCAAAGAAAACGCCTCCATAATGCAGCCTCCAAACTGCACAAATTGAAAAGTGAAGGATTCATGAAAGTTCTTAAATGTGAAGTGG
AATTGATGGCCAGGATGGCAAAAACCATTGACAGCTTCACTCAGAATCAGACAAGGCTGGTGGTCATCATCGATGGATTAGATGCCTGTG
AGCAGGACAAAGTCCTTCAGATGCTGGACACTGTCCGAGTTCTGTTTTCAAAAGGCCCGTTCATTGCCATTTTTGCAAGTGATCCACATA
TTATCATAAAGGCAATTAACCAGAACCTCAATAGTGTGCTTCGGGATTCAAATATAAATGGCCATGACTACATGCGCAACATAGTCCACT
TGCCTGTGTTCCTTAATAGTCGTGGACTAAGCAATGCAAGAAAATTTCTCGTAACTTCAGCAACAAATGGAGACGTTCCATGCTCAGATA
CTACAGGGATACAGGAAGATGCTGACAGAAGAGTTTCACAGAACAGCCTTGGGGAGATGACAAAACTTGGTAGCAAGACAGCCCTCAATA
GACGGGACACTTACCGAAGAAGGCAGATGCAGAGGACCATCACTCGCCAGATGTCCTTTGATCTTACAAAACTGCTGGTTACCGAGGACT
GGTTCAGTGACATCAGTCCCCAGACCATGAGAAGATTACTTAATATTGTTTCTGTGACAGGACGATTACTGAGAGCCAATCAGATTAGTT
TCAACTGGGACAGGCTTGCTAGCTGGATCAACCTTACTGAGCAGTGGCCATACCGGACTTCATGGCTCATATTATATTTGGAAGAGACTG
AAGGTATTCCAGATCAAATGACATTAAAAACCATCTACGAAAGAATATCAAAGAATATTCCAACAACTAAGGATGTTGAGCCACTTCTTG
AAATTGATGGAGATATAAGAAATTTTGAAGTGTTTTTGTCTTCAAGGACCCCAGTTCTTGTGGCTCGAGATGTAAAAGTCTTTTTGCCAT
GCACTGTAAACCTAGATCCCAAACTACGGGAAATTATTGCAGATGTTCGTGCTGCCAGAGAGCAGATCAGTATTGGAGGACTGGCGTACC
CCCCGCTCCCTCTACATGAGGGTCCTCCTAGGGCGCCATCAGGGTACAGCCAGCCCCCATCCGTGTGCTCTTCCACGTCCTTCAATGGGC
CCTTCGCAGGTGGAGTGGTGTCACCACAGCCTCACAGCAGCTATTACAGCGGCATGACGGGCCCTCAGCATCCCTTCTACAACAGGGTCG
GCGGAAGCAGAAGTGGGCTGTGGATCCTCAGAACACTGCCTGGAGTAATGACGATTCCAAGTTTGGCCAGCGGATGCTAGAGAAGATGGG
GTGGTCTAAAGGAAAGGGTTTAGGGGCTCAGGAGCAAGGAGCCACAGATCATATTAAAGTTCAAGTGAAAAATAACCACCTGGGACTCGG
AGCTACCATCAATAATGAAGACAACTGGATTGCCCATCAGGATGATTTTAACCAGCTTCTGGCCGAACTGAACACTTGCCATGGGCAGGA
AACCACAGATTCCTCGGACAAGAAGGAAAAGAAATCTTTTAGCCTTGAGGAAAAGTCCAAAATCTCCAAAAACCGTGTTCACTATATGAA
ATTCACAAAAGGAAAGTCGTGGAAGGCGCTGACGCTGTCCCAGAAGAGGCCGTACGTGGACGAGGCGGAGCGGCTGCGCCTGCAGCACAT
GCAGGACTACCCCAACTACAAGTACCGGCCGCGCAGGAAGAAGCAGGCCAAGCGGCTGTGCAAGCGCGTGGACCCGGGCTTCCTTCTGAG
CTCCCTCTCCCGGGACCAGAACGCCCTGCCGGAGAAGAGAAGCGGCAGCCGGGGGGCGCTGGGGGAGAAGGAGGACAGGGGTGAGTACTC
CCCCGGCACTGCCCTGCCCAGCCTCCGGGGCTGCTACCACGAGGGGCCGGCTGGTGGTGGCGGCGGCGGCACCCCGAGCAGTGTGGACAC
GTACCCGTACGGGCTGCCCACACCTCCTGAAATGTCTCCCCTGGACGTGCTGGAGCCGGAGCAGACCTTCTTCTCCTCCCCCTGCCAGGA
GGAGCATGGCCATCCCCGCCGCATCCCCCACCTGCCAGGGCACCCGTACTCACCGGAGTACGCCCCAAGCCCTCTCCACTGTAGCCACCC
CCTGGGCTCCCTGGCCCTTGGCCAGTCCCCCGGCGTCTCCATGATGTCCCCTGTACCCGGCTGTCCCCCATCTCCTGCCTATTACTCCCC
GGCCACCTACCACCCACTCCACTCCAACCTCCAAGCCCACCTGGGCCAGCTTTCCCCGCCTCCTGAGCACCCTGGCTTCGACGCCCTGGA
TCAACTGAGCCAGGTGGAACTCCTGGGGGACATGGATCGCAATGAATTCGACCAGTATTTGAACACTCCTGGCCACCCAGACTCCGCCAC
AGGGGCCATGGCCCTCAGTGGGCATGTTCCGGTCTCCCAGGTGACACCAACGGGTCCCACAGAGACCAGCCTCATCTCCGTCCTGGCTGA
TGCCACGGCCACGTACTACAACAGCTACAGTGTGTCATAGAGCTGGAGGCGCCCCGTCCGGTCAGCCCTCGCGCCCTCTCCTTCTTGTGC
CTTGAGTGGCAGAGGAGCCGTCCAGCCACACCAGCTTTCCTCCCACCGCTCAGGGCAGGGAGGTCTGAACTGCGGCCCCAGAGCCTTTGG
CCTAAGCTGGACTCTCCTTATCCGAGTGCCGCCTCTATCCCCTTCCCCACGTTCCAGCCCCTGCAGCCCACATTTTAAGTATATTCCTTC
AAGTGAGTTTTCCTCCAGCCCCTGAGAGTTGCTGTCTCCCAGTGGAATGTTCACTGACGTCTTTTCTTGGTAGCCATCATCGAAACTAAT

>42514_42514_2_KIDINS220-SOX7_KIDINS220_chr2_8890242_ENST00000418530_SOX7_chr8_10692285_ENST00000554914_length(amino acids)=1171AA_BP=1144
MQLSVKMSVLISQSVINYVEEENIPALKALLEKCKDVDERNECGQTPLMIAAEQGNLEIVKELIKNGANCNLEDLDNWTALISASKEGHV
HIVEELLKCGVNLEHRDMGGWTALMWACYKGRTDVVELLLSHGANPSVTGLYSVYPIIWAAGRGHADIVHLLLQNGAKVNCSDKYGTTPL
VWAARKGHLECVKHLLAMGADVDQEGANSMTALIVAVKGGYTQSVKEILKRNPNVNLTDKDGNTALMIASKEGHTEIVQDLLDAGTYVNI
PDRSGDTVLIGAVRGGHVEIVRALLQKYADIDIRGQDNKTALYWAVEKGNATMVRDILQCNPDTEICTKDGETPLIKATKMRNIEVVELL
LDKGAKVSAVDKKGDTPLHIAIRGRSRKLAELLLRNPKDGRLLYRPNKAGETPYNIDCSHQKSILTQIFGARHLSPTETDGDMLGYDLYS
SALADILSEPTMQPPICVGLYAQWGSGKSFLLKKLEDEMKTFAGQQIEPLFQFSWLIVFLTLLLCGGLGLLFAFTVHPNLGIAVSLSFLA
LLYIFFIVIYFGGRREGESWNWAWVLSTRLARHIGYLELLLKLMFVNPPELPEQTTKALPVRFLFTDYNRLSSVGGETSLAEMIATLSDA
CEREFGFLATRLFRVFKTEDTQGKKKWKKTCCLPSFVIFLFIIGCIISGITLLAIFRVDPKHLTVNAVLISIASVVGLAFVLNCRTWWQV
LDSLLNSQRKRLHNAASKLHKLKSEGFMKVLKCEVELMARMAKTIDSFTQNQTRLVVIIDGLDACEQDKVLQMLDTVRVLFSKGPFIAIF
ASDPHIIIKAINQNLNSVLRDSNINGHDYMRNIVHLPVFLNSRGLSNARKFLVTSATNGDVPCSDTTGIQEDADRRVSQNSLGEMTKLGS
KTALNRRDTYRRRQMQRTITRQMSFDLTKLLVTEDWFSDISPQTMRRLLNIVSVTGRLLRANQISFNWDRLASWINLTEQWPYRTSWLIL
YLEETEGIPDQMTLKTIYERISKNIPTTKDVEPLLEIDGDIRNFEVFLSSRTPVLVARDVKVFLPCTVNLDPKLREIIADVRAAREQISI
GGLAYPPLPLHEGPPRAPSGYSQPPSVCSSTSFNGPFAGGVVSPQPHSSYYSGMTGPQHPFYNRVGGSRSGLWILRTLPGVMTIPSLASG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for KIDINS220-SOX7


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for KIDINS220-SOX7


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for KIDINS220-SOX7


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource