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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:KIF1B-HAGH (FusionGDB2 ID:42600) |
Fusion Gene Summary for KIF1B-HAGH |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KIF1B-HAGH | Fusion gene ID: 42600 | Hgene | Tgene | Gene symbol | KIF1B | HAGH | Gene ID | 23095 | 3029 |
| Gene name | kinesin family member 1B | hydroxyacylglutathione hydrolase | |
| Synonyms | CMT2|CMT2A|CMT2A1|HMSNII|KLP|NBLST1 | GLO2|GLX2|GLXII|HAGH1 | |
| Cytomap | 1p36.22 | 16p13.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | kinesin-like protein KIF1Bkinesin superfamily protein KIF1B | hydroxyacylglutathione hydrolase, mitochondrialglyoxalase IIhydroxyacylglutathione hydroxylase | |
| Modification date | 20200328 | 20200313 | |
| UniProtAcc | O60333 | Q6PII5 | |
| Ensembl transtripts involved in fusion gene | ENST00000263934, ENST00000377081, ENST00000377086, ENST00000377083, ENST00000377093, ENST00000465635, | ENST00000397353, ENST00000566709, ENST00000567398, ENST00000397356, ENST00000455446, | |
| Fusion gene scores | * DoF score | 18 X 19 X 14=4788 | 4 X 2 X 4=32 |
| # samples | 24 | 4 | |
| ** MAII score | log2(24/4788*10)=-4.31831684133498 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(4/32*10)=0.321928094887362 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0 | |
| Context | PubMed: KIF1B [Title/Abstract] AND HAGH [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | KIF1B(10428596)-HAGH(1873038), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | KIF1B-HAGH seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF. KIF1B-HAGH seems lost the major protein functional domain in Tgene partner, which is a cell metabolism gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | HAGH | GO:0006750 | glutathione biosynthetic process | 8550579 |
| Fusion gene breakpoints across KIF1B (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across HAGH (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | UCS | TCGA-NA-A4R1-01A | KIF1B | chr1 | 10428596 | - | HAGH | chr16 | 1873038 | - |
| ChimerDB4 | UCS | TCGA-NA-A4R1-01A | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| ChimerDB4 | UCS | TCGA-NA-A4R1 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
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Fusion Gene ORF analysis for KIF1B-HAGH |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000263934 | ENST00000397353 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| 5CDS-5UTR | ENST00000263934 | ENST00000566709 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| 5CDS-5UTR | ENST00000377081 | ENST00000397353 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| 5CDS-5UTR | ENST00000377081 | ENST00000566709 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| 5CDS-5UTR | ENST00000377086 | ENST00000397353 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| 5CDS-5UTR | ENST00000377086 | ENST00000566709 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| 5CDS-intron | ENST00000263934 | ENST00000567398 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| 5CDS-intron | ENST00000377081 | ENST00000567398 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| 5CDS-intron | ENST00000377086 | ENST00000567398 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| Frame-shift | ENST00000263934 | ENST00000397356 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| Frame-shift | ENST00000377081 | ENST00000397356 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| Frame-shift | ENST00000377086 | ENST00000397356 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| In-frame | ENST00000263934 | ENST00000455446 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| In-frame | ENST00000377081 | ENST00000455446 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| In-frame | ENST00000377086 | ENST00000455446 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-3CDS | ENST00000377083 | ENST00000397356 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-3CDS | ENST00000377083 | ENST00000455446 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-3CDS | ENST00000377093 | ENST00000397356 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-3CDS | ENST00000377093 | ENST00000455446 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-3CDS | ENST00000465635 | ENST00000397356 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-3CDS | ENST00000465635 | ENST00000455446 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-5UTR | ENST00000377083 | ENST00000397353 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-5UTR | ENST00000377083 | ENST00000566709 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-5UTR | ENST00000377093 | ENST00000397353 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-5UTR | ENST00000377093 | ENST00000566709 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-5UTR | ENST00000465635 | ENST00000397353 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-5UTR | ENST00000465635 | ENST00000566709 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-intron | ENST00000377083 | ENST00000567398 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-intron | ENST00000377093 | ENST00000567398 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| intron-intron | ENST00000465635 | ENST00000567398 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000263934 | KIF1B | chr1 | 10428596 | + | ENST00000455446 | HAGH | chr16 | 1873038 | - | 5992 | 4839 | 33 | 4889 | 1618 |
| ENST00000377086 | KIF1B | chr1 | 10428596 | + | ENST00000455446 | HAGH | chr16 | 1873038 | - | 6179 | 5026 | 103 | 5076 | 1657 |
| ENST00000377081 | KIF1B | chr1 | 10428596 | + | ENST00000455446 | HAGH | chr16 | 1873038 | - | 6056 | 4903 | 43 | 4953 | 1636 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000263934 | ENST00000455446 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - | 0.001174694 | 0.99882525 |
| ENST00000377086 | ENST00000455446 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - | 0.001403281 | 0.9985967 |
| ENST00000377081 | ENST00000455446 | KIF1B | chr1 | 10428596 | + | HAGH | chr16 | 1873038 | - | 0.001205203 | 0.9987948 |
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Fusion Genomic Features for KIF1B-HAGH |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for KIF1B-HAGH |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:10428596/chr16:1873038) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KIF1B | HAGH |
| FUNCTION: Motor for anterograde transport of mitochondria. Has a microtubule plus end-directed motility. Isoform 2 is required for induction of neuronal apoptosis. {ECO:0000269|PubMed:18334619}.; FUNCTION: Isoform 1 mediates the transport of synaptic vesicles in neuronal cells. {ECO:0000250|UniProtKB:O88658}. | FUNCTION: Hydrolase acting on ester bonds. {ECO:0000305}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000263934 | + | 42 | 47 | 365_386 | 1562 | 1771.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000263934 | + | 42 | 47 | 470_502 | 1562 | 1771.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000263934 | + | 42 | 47 | 668_737 | 1562 | 1771.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000263934 | + | 42 | 47 | 841_869 | 1562 | 1771.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377081 | + | 43 | 48 | 365_386 | 1608 | 1824.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377081 | + | 43 | 48 | 470_502 | 1608 | 1824.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377081 | + | 43 | 48 | 668_737 | 1608 | 1824.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377081 | + | 43 | 48 | 841_869 | 1608 | 1824.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377086 | + | 44 | 49 | 365_386 | 1608 | 1817.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377086 | + | 44 | 49 | 470_502 | 1608 | 1817.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377086 | + | 44 | 49 | 668_737 | 1608 | 1817.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377086 | + | 44 | 49 | 841_869 | 1608 | 1817.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000263934 | + | 42 | 47 | 556_612 | 1562 | 1771.0 | Domain | FHA |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000263934 | + | 42 | 47 | 5_354 | 1562 | 1771.0 | Domain | Kinesin motor |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377081 | + | 43 | 48 | 556_612 | 1608 | 1824.0 | Domain | FHA |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377081 | + | 43 | 48 | 5_354 | 1608 | 1824.0 | Domain | Kinesin motor |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377086 | + | 44 | 49 | 556_612 | 1608 | 1817.0 | Domain | FHA |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377086 | + | 44 | 49 | 5_354 | 1608 | 1817.0 | Domain | Kinesin motor |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000263934 | + | 42 | 47 | 97_104 | 1562 | 1771.0 | Nucleotide binding | ATP |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377081 | + | 43 | 48 | 97_104 | 1608 | 1824.0 | Nucleotide binding | ATP |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377086 | + | 44 | 49 | 97_104 | 1608 | 1817.0 | Nucleotide binding | ATP |
| Tgene | HAGH | chr1:10428596 | chr16:1873038 | ENST00000397353 | 1 | 10 | 191_193 | 0 | 261.0 | Region | Substrate binding | |
| Tgene | HAGH | chr1:10428596 | chr16:1873038 | ENST00000397353 | 1 | 10 | 221_223 | 0 | 261.0 | Region | Substrate binding | |
| Tgene | HAGH | chr1:10428596 | chr16:1873038 | ENST00000397353 | 1 | 10 | 297_300 | 0 | 261.0 | Region | Substrate binding | |
| Tgene | HAGH | chr1:10428596 | chr16:1873038 | ENST00000397356 | 0 | 9 | 191_193 | 25 | 309.0 | Region | Substrate binding | |
| Tgene | HAGH | chr1:10428596 | chr16:1873038 | ENST00000397356 | 0 | 9 | 221_223 | 25 | 309.0 | Region | Substrate binding | |
| Tgene | HAGH | chr1:10428596 | chr16:1873038 | ENST00000397356 | 0 | 9 | 297_300 | 25 | 309.0 | Region | Substrate binding |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377083 | + | 1 | 21 | 365_386 | 0 | 1154.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377083 | + | 1 | 21 | 470_502 | 0 | 1154.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377083 | + | 1 | 21 | 668_737 | 0 | 1154.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377083 | + | 1 | 21 | 841_869 | 0 | 1154.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377093 | + | 1 | 21 | 365_386 | 0 | 1154.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377093 | + | 1 | 21 | 470_502 | 0 | 1154.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377093 | + | 1 | 21 | 668_737 | 0 | 1154.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377093 | + | 1 | 21 | 841_869 | 0 | 1154.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000263934 | + | 42 | 47 | 1702_1799 | 1562 | 1771.0 | Domain | PH |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377081 | + | 43 | 48 | 1702_1799 | 1608 | 1824.0 | Domain | PH |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377083 | + | 1 | 21 | 1702_1799 | 0 | 1154.0 | Domain | PH |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377083 | + | 1 | 21 | 556_612 | 0 | 1154.0 | Domain | FHA |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377083 | + | 1 | 21 | 5_354 | 0 | 1154.0 | Domain | Kinesin motor |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377086 | + | 44 | 49 | 1702_1799 | 1608 | 1817.0 | Domain | PH |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377093 | + | 1 | 21 | 1702_1799 | 0 | 1154.0 | Domain | PH |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377093 | + | 1 | 21 | 556_612 | 0 | 1154.0 | Domain | FHA |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377093 | + | 1 | 21 | 5_354 | 0 | 1154.0 | Domain | Kinesin motor |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377083 | + | 1 | 21 | 97_104 | 0 | 1154.0 | Nucleotide binding | ATP |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377093 | + | 1 | 21 | 97_104 | 0 | 1154.0 | Nucleotide binding | ATP |
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Fusion Gene Sequence for KIF1B-HAGH |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >42600_42600_1_KIF1B-HAGH_KIF1B_chr1_10428596_ENST00000263934_HAGH_chr16_1873038_ENST00000455446_length(transcript)=5992nt_BP=4839nt CCCGGCCCCCCGCGCCCCCGCGCGCCGCGGCTCCTGTTGACCCGGTCCGCCCGTCGGTCTGCAGCGCGGCTGAGGAAACTTGGCTGTAAC TTCAAAAGAAGATTTGATTCTTTATTTCTGGACTGCATATATATATATAACAAGGCCATTAAAATGTCGGGAGCCTCAGTGAAGGTGGCT GTCCGGGTAAGGCCCTTCAATTCTCGAGAGACCAGCAAGGAATCCAAATGCATCATTCAGATGCAAGGCAACTCGACCAGTATTATTAAC CCAAAGAATCCAAAGGAAGCTCCAAAGTCCTTCAGCTTCGACTATTCCTACTGGTCTCATACCTCACCCGAAGATCCCTGTTTTGCATCT CAAAACCGTGTGTACAATGACATTGGCAAGGAAATGCTCTTACACGCCTTTGAGGGATATAATGTCTGTATTTTTGCCTATGGGCAGACT GGTGCTGGAAAATCTTATACAATGATGGGTAAACAAGAAGAAAGCCAGGCTGGCATCATTCCACAGTTATGTGAAGAACTTTTTGAGAAA ATCAATGACAACTGTAATGAAGAAATGTCTTACTCTGTAGAGGTGAGCTACATGGAAATTTACTGTGAAAGAGTACGAGATTTGCTGAAT CCAAAAAACAAGGGTAATTTGCGTGTGCGTGAACACCCACTTCTTGGACCCTATGTGGAGGATCTGTCCAAGTTGGCAGTTACTTCCTAC ACAGACATTGCTGACCTCATGGATGCTGGGAACAAAGCCAGGACAGTGGCAGCTACAAACATGAATGAAACAAGTAGCCGTTCCCACGCT GTGTTTACGATTGTTTTCACCCAGAAGAAACACGATAATGAGACCAACCTTTCCACTGAGAAGGTCAGTAAAATCAGCTTGGTGGATCTA GCAGGAAGTGAACGAGCTGATTCAACTGGTGCCAAAGGGACTCGATTAAAGGAAGGAGCAAATATTAATAAGTCTCTTACAACTTTGGGC AAAGTCATTTCAGCCTTGGCCGAGGTGAGTAAAAAGAAGAAGAAAACAGATTTTATTCCCTACAGGGATTCTGTACTTACTTGGCTCCTT CGAGAAAATTTAGGTGGCAATTCTCGGACTGCAATGGTTGCTGCTCTGAGCCCCGCGGATATCAACTACGATGAGACTTTGAGCACTCTG AGATATGCAGATCGTGCAAAACAAATTAAATGCAATGCTGTTATCAATGAGGACCCCAATGCCAAACTGGTTCGTGAATTAAAGGAGGAG GTGACACGGCTGAAGGACCTTCTTCGTGCTCAGGGCCTGGGAGATATTATTGATACATCCATGGGGTCCCTCACTTCATCCCCATCTTCC TGCTCACTCAGTAGTCAGGTGGGCTTGACGTCTGTGACCAGTATTCAAGAGAGGATCATGTCTACACCTGGAGGAGAGGAAGCTATTGAA CGTTTAAAGGAATCAGAGAAGATCATTGCTGAGTTGAATGAAACTTGGGAAGAGAAGCTTCGTAAAACAGAGGCCATCAGAATGGAGAGA GAGGCTTTGTTGGCTGAGATGGGAGTTGCCATTCGGGAAGATGGAGGAACCCTAGGGGTTTTCTCACCTAAAAAGACCCCACATCTTGTT AACCTCAATGAAGACCCACTAATGTCTGAGTGCCTACTTTATTACATCAAAGATGGAATTACAAGGGTTGGCCAAGCAGATGCTGAGCGG CGCCAGGACATAGTGCTGAGCGGGGCTCACATTAAAGAAGAGCATTGTATCTTCCGGAGTGAGAGAAGCAACAGCGGGGAAGTTATCGTG ACCTTAGAGCCCTGTGAGCGCTCAGAAACCTACGTAAATGGCAAGAGGGTGTCCCAGCCTGTTCAGCTGCGCTCAGGAAACCGTATCATC ATGGGTAAAAACCATGTTTTCCGCTTTAACCACCCGGAACAAGCACGAGCTGAGCGAGAGAAGACTCCTTCTGCTGAGACCCCCTCTGAG CCTGTGGACTGGACATTTGCCCAGAGGGAGCTTCTGGAAAAACAAGGAATTGATATGAAACAAGAGATGGAGAAAAGGCTACAGGAAATG GAGATCTTATACAAAAAGGAGAAGGAAGAAGCAGATCTTCTTTTGGAGCAGCAGAGACTGGACTATGAGAGTAAATTGCAGGCCTTGCAG AAGCAGGTTGAAACCCGATCTCTGGCTGCAGAAACAACTGAAGAGGAGGAAGAAGAGGAAGAAGTTCCTTGGACACAGCATGAATTTGAG TTGGCCCAATGGGCCTTCCGGAAATGGAAGTCTCATCAGTTTACTTCATTACGGGACTTACTCTGGGGCAATGCCGTGTACCTAAAGGAG GCCAATGCCATCAGTGTGGAACTGAAAAAGAAGGTGCAGTTTCAGTTTGTTCTGCTGACTGACACACTGTACTCCCCTTTGCCTCCTGAA TTACTTCCCACTGAGATGGAAAAAACTCATGAGGACAGGCCTTTCCCTCGCACAGTGGTAGCAGTAGAAGTCCAGGATTTGAAGAATGGA GCAACACACTATTGGTCTTTGGAGAAACTCAAGCAGAGGCTGGATTTGATGCGAGAGATGTATGATAGGGCAGGGGAGATGGCCTCCAGT GCCCAAGACGAAAGCGAAACCACTGTGACTGGCAGCGATCCCTTCTATGATCGGTTCCACTGGTTCAAACTTGTGGGGAGCTCCCCCATT TTCCACGGCTGTGTGAACGAGCGCCTTGCCGACCGCACACCCTCCCCCACTTTTTCCACGGCCGATTCCGACATCACTGAGCTGGCTGAC GAGCAGCAAGATGAGATGGAGGATTTTGATGATGAGGCATTCGTGGATGACGCCGGCTCTGACGCAGGGACGGAGGAGGGATCAGATCTC TTCAGTGACGGGCATGACCCGTTTTACGACCGATCCCCTTGGTTCATTTTAGTGGGAAGGGCATTTGTTTACCTGAGCAATCTGCTGTAT CCCGTGCCCCTGATCCACAGGGTGGCCATCGTCAGTGAGAAAGGTGAAGTGCGGGGATTTCTGCGTGTGGCTGTACAGGCCATCGCAGCG GATGAAGAAGCTCCTGATTATGGCTCTGGAATTCGACAGTCAGGAACAGCTAAAATATCTTTTGATAATGAATACTTTAATCAGAGTGAC TTTTCGTCTGTTGCAATGACTCGTTCTGGTCTGTCCTTGGAGGAGTTGAGGATTGTGGAAGGACAGGGTCAGAGTTCTGAGGTCATCACT CCTCCAGAAGAAATCAGTCGAATTAATGACTTGGATTTGAAGTCAAGCACTTTGCTGGATGGTAAGATGGTAATGGAAGGGTTTTCTGAA GAGATTGGCAACCACCTGAAACTGGGCAGTGCCTTCACTTTCCGAGTAACAGTGTTGCAGGCCAGTGGAATCCTCCCAGAGTATGCAGAT ATCTTCTGTCAGTTCAACTTTTTGCATCGCCATGATGAAGCATTCTCCACGGAGCCCCTCAAAAACAATGGCAGAGGAAGTCCCCTGGCC TTTTATCATGTGCAGAATATTGCAGTGGAGATCACTGAATCATTTGTGGATTACATCAAAACCAAGCCTATTGTATTTGAAGTCTTTGGG CATTATCAGCAGCACCCACTTCATCTGCAAGGACAGGAGCTTAACAGTCCGCCTCAGCCGTGCCGCCGATTCTTCCCTCCACCCATGCCA CTGTCCAAGCCAGTTCCAGCCACCAAGTTAAACACGATGAGCAAAACCAGCCTTGGCCAGAGCATGAGCAAGTATGACCTCCTGGTTTGG TTTGAGATCAGTGAACTGGAGCCTACAGGAGAGTATATCCCAGCTGTGGTTGACCACACAGCAGGCTTGCCTTGCCAGGGGACATTTTTG CTTCATCAGGGCATCCAGCGAAGGATCACAGTGACCATTATCCATGAGAAGGGGAGCGAGCTCCATTGGAAAGATGTTCGTGAACTGGTG GTAGGTCGTATTCGGAATAAGCCTGAGGTGGATGAAGCTGCAGTTGATGCCATCCTCTCCCTAAATATTATTTCTGCCAAGTACCTGAAG TCTTCCCACAACTCTAGCAGGACCTTCTACCGCTTTGAGGCTGTGTGGGATAGCTCTCTGCATAACTCCCTTCTTCTGAACCGAGTGACA CCCTATGGAGAAAAGATCTACATGACCTTGTCGGCCTACCTAGAGCTGGATCATTGCATCCAGCCGGCTGTCATCACCAAGGATGTGTGC ATGGTCTTCTACTCCCGAGATGCCAAGATCTCACCACCACGCTCTCTGCGTAGCCTCTTTGGCAGCGGCTACTCAAAGTCACCAGATTCG AATCGAGTCACTGGCATTTACGAACTCAGCTTATGCAAAATGTCAGACACAGGTAGTCCAGGTATGCAGAGAAGGAGAAGAAAAATCTTA GATACGTCAGTGGCATATGTGCGGGGAGAAGAGAACTTAGCAGGCTGGCGGCCCCGTGGAGACAGCCTCATCCTTGAGCACCAGTGGGAG CTGGAGAAGCTGGAGCTCCTACATGAGGTGGAAAAAACCCGCCACTTTTTGCTGCTGCGTGAGAGACTTGGTGACAGCATCCCCAAATCC CTGAGCGACTCGTTATCCCCCAGCCTCAGCAGTGGGACCCTCAGCACCTCCACCAGTATCTCCTCTCAGATCTCAACCACTACCTTTGAA AGCGCCATCACACCTAGCGAGAGCAGTGGCTATGATTCAGGAGACATCGAAAGCCTGGTGGACCGAGAGAAAGAGCTGGCTACCAAGTGC CTGCAACTTCTCACCCACACTTTCAACAGAGAATTCAGCCAGGTGCACGGCAGCGTCAGTGACTGTAAGGTCCAGCCCTGCTGGGAGTTT TCTGCCACACAGATTTGCGGAAGAACCTGACCGTGGACGAGGGCACCATGAAGGTAGAGGTGCTGCCTGCCCTGACCGACAACTACATGT ACCTGGTCATTGATGATGAGACCAAGGAGGCTGCCATTGTGGATCCGGTGCAGCCCCAGAAGGTCGTGGACGCGGCGAGAAAGCACGGGG TGAAACTGACCACAGTGCTCACCACCCACCACCACTGGGACCATGCTGGCGGGAATGAGAAACTGGTCAAGCTGGAGTCGGGACTGAAGG TGTACGGGGGTGACGACCGTATCGGGGCCCTGACTCACAAGATCACTCACCTGTCCACACTGCAGGTGACACCTTGTTTGTGGCTGGCTG CGGGAAGTTCTATGAAGGGACTGCGGATGAGATGTGTAAAGCTCTGCTGGAGGTCTTGGGCCGGCTCCCCCCGGACACAAGAGTCTACTG TGGCCACGAGTACACCATCAACAACCTCAAGTTTGCACGCCACGTGGAGCCCGGCAATGCCGCCATCCGGGAGAAGCTGGCCTGGGCCAA GGAGAAGTACAGCATCGGGGAGCCCACAGTGCCATCCACCCTGGCAGAGGAGTTTACCTACAACCCCTTCATGAGAGTGAGGGAGAAGAC GGTGCAGCAGCACGCAGGTGAGACGGACCCGGTGACCACCATGCGGGCCGTGCGCAGGGAGAAGGACCAGTTCAAGATGCCCCGGGACTG AGGCCGCCCTGCACCTTCAGCGGATTTGGGGATTAGGCTCTTTTAGGTAACTGGCTTTCCTGCTGGTCCGTGCGGGAAATTCAGTCTTGA TTTAACCTTAATTTTACAGCCCTTGGCTTGTGTTATCGGACATTCTAATGCATATTTATAAGAGAAGTTTAACAAGTATTTATTCCCATA ACTTCCCCTTGCAGACTGTTTTCTTCTGGCCTTTAGGCCTCTGCTTGTCCCCTCGGGCCTCCTTCCTCCTCCGTGAGCCACTGCAGTCCC CCCACCCACGCTTCAGGTCAGGCGTGAGCCGGTGCCTTTGCTGTGGCCTTGGCTGGGTGCTGATGGGACTGTCAGGCCCACTGCTGCGGT >42600_42600_1_KIF1B-HAGH_KIF1B_chr1_10428596_ENST00000263934_HAGH_chr16_1873038_ENST00000455446_length(amino acids)=1618AA_BP=1602 MLTRSARRSAARLRKLGCNFKRRFDSLFLDCIYIYNKAIKMSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSF SFDYSYWSHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLCEELFEKINDNCNEEMSY SVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKH DNETNLSTEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTA MVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDTSMGSLTSSPSSCSLSSQVGLTS VTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSEC LLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFRFNH PEQARAEREKTPSAETPSEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLDYESKLQALQKQVETRSLAAE TTEEEEEEEEVPWTQHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVELKKKVQFQFVLLTDTLYSPLPPELLPTEMEKTHE DRPFPRTVVAVEVQDLKNGATHYWSLEKLKQRLDLMREMYDRAGEMASSAQDESETTVTGSDPFYDRFHWFKLVGSSPIFHGCVNERLAD RTPSPTFSTADSDITELADEQQDEMEDFDDEAFVDDAGSDAGTEEGSDLFSDGHDPFYDRSPWFILVGRAFVYLSNLLYPVPLIHRVAIV SEKGEVRGFLRVAVQAIAADEEAPDYGSGIRQSGTAKISFDNEYFNQSDFSSVAMTRSGLSLEELRIVEGQGQSSEVITPPEEISRINDL DLKSSTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQASGILPEYADIFCQFNFLHRHDEAFSTEPLKNNGRGSPLAFYHVQNIAVEI TESFVDYIKTKPIVFEVFGHYQQHPLHLQGQELNSPPQPCRRFFPPPMPLSKPVPATKLNTMSKTSLGQSMSKYDLLVWFEISELEPTGE YIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSELHWKDVRELVVGRIRNKPEVDEAAVDAILSLNIISAKYLKSSHNSSRTFYR FEAVWDSSLHNSLLLNRVTPYGEKIYMTLSAYLELDHCIQPAVITKDVCMVFYSRDAKISPPRSLRSLFGSGYSKSPDSNRVTGIYELSL CKMSDTGSPGMQRRRRKILDTSVAYVRGEENLAGWRPRGDSLILEHQWELEKLELLHEVEKTRHFLLLRERLGDSIPKSLSDSLSPSLSS -------------------------------------------------------------- >42600_42600_2_KIF1B-HAGH_KIF1B_chr1_10428596_ENST00000377081_HAGH_chr16_1873038_ENST00000455446_length(transcript)=6056nt_BP=4903nt GAAACTTGGCTGTAACTTCAAAAGAAGATTTGATTCTTTATTTCTGGACTGCATATATATATATAACAAGGCCATTAAAATGTCGGGAGC CTCAGTGAAGGTGGCTGTCCGGGTAAGGCCCTTCAATTCTCGAGAGACCAGCAAGGAATCCAAATGCATCATTCAGATGCAAGGCAACTC GACCAGTATTATTAACCCAAAGAATCCAAAGGAAGCTCCAAAGTCCTTCAGCTTCGACTATTCCTACTGGTCTCATACCTCACCCGAAGA TCCCTGTTTTGCATCTCAAAACCGTGTGTACAATGACATTGGCAAGGAAATGCTCTTACACGCCTTTGAGGGATATAATGTCTGTATTTT TGCCTATGGGCAGACTGGTGCTGGAAAATCTTATACAATGATGGGTAAACAAGAAGAAAGCCAGGCTGGCATCATTCCACAGTTATGTGA AGAACTTTTTGAGAAAATCAATGACAACTGTAATGAAGAAATGTCTTACTCTGTAGAGGTGAGCTACATGGAAATTTACTGTGAAAGAGT ACGAGATTTGCTGAATCCAAAAAACAAGGGTAATTTGCGTGTGCGTGAACACCCACTTCTTGGACCCTATGTGGAGGATCTGTCCAAGTT GGCAGTTACTTCCTACACAGACATTGCTGACCTCATGGATGCTGGGAACAAAGCCAGGACAGTGGCAGCTACAAACATGAATGAAACAAG TAGCCGTTCCCACGCTGTGTTTACGATTGTTTTCACCCAGAAGAAACACGATAATGAGACCAACCTTTCCACTGAGAAGGTCAGTAAAAT CAGCTTGGTGGATCTAGCAGGAAGTGAACGAGCTGATTCAACTGGTGCCAAAGGGACTCGATTAAAGGAAGGAGCAAATATTAATAAGTC TCTTACAACTTTGGGCAAAGTCATTTCAGCCTTGGCCGAGGTGGATAACTGCACTAGCAAGAGTAAAAAGAAGAAGAAAACAGATTTTAT TCCCTACAGGGATTCTGTACTTACTTGGCTCCTTCGAGAAAATTTAGGTGGCAATTCTCGGACTGCAATGGTTGCTGCTCTGAGCCCCGC GGATATCAACTACGATGAGACTTTGAGCACTCTGAGATATGCAGATCGTGCAAAACAAATTAAATGCAATGCTGTTATCAATGAGGACCC CAATGCCAAACTGGTTCGTGAATTAAAGGAGGAGGTGACACGGCTGAAGGACCTTCTTCGTGCTCAGGGCCTGGGAGATATTATTGATAT TGATCCATTGATCGATGATTACTCTGGAAGTGGAAGCAAATATCTGAAAGATTTTCAGAACAATAAGCATAGATACTTGCTAGCCTCTGA GAATCAACGCCCTGGCCATTTTTCCACAGCATCCATGGGGTCCCTCACTTCATCCCCATCTTCCTGCTCACTCAGTAGTCAGGTGGGCTT GACGTCTGTGACCAGTATTCAAGAGAGGATCATGTCTACACCTGGAGGAGAGGAAGCTATTGAACGTTTAAAGGAATCAGAGAAGATCAT TGCTGAGTTGAATGAAACTTGGGAAGAGAAGCTTCGTAAAACAGAGGCCATCAGAATGGAGAGAGAGGCTTTGTTGGCTGAGATGGGAGT TGCCATTCGGGAAGATGGAGGAACCCTAGGGGTTTTCTCACCTAAAAAGACCCCACATCTTGTTAACCTCAATGAAGACCCACTAATGTC TGAGTGCCTACTTTATTACATCAAAGATGGAATTACAAGGGTTGGCCAAGCAGATGCTGAGCGGCGCCAGGACATAGTGCTGAGCGGGGC TCACATTAAAGAAGAGCATTGTATCTTCCGGAGTGAGAGAAGCAACAGCGGGGAAGTTATCGTGACCTTAGAGCCCTGTGAGCGCTCAGA AACCTACGTAAATGGCAAGAGGGTGTCCCAGCCTGTTCAGCTGCGCTCAGGAAACCGTATCATCATGGGTAAAAACCATGTTTTCCGCTT TAACCACCCGGAACAAGCACGAGCTGAGCGAGAGAAGACTCCTTCTGCTGAGACCCCCTCTGAGCCTGTGGACTGGACATTTGCCCAGAG GGAGCTTCTGGAAAAACAAGGAATTGATATGAAACAAGAGATGGAGAAAAGGCTACAGGAAATGGAGATCTTATACAAAAAGGAGAAGGA AGAAGCAGATCTTCTTTTGGAGCAGCAGAGACTGGACTATGAGAGTAAATTGCAGGCCTTGCAGAAGCAGGTTGAAACCCGATCTCTGGC TGCAGAAACAACTGAAGAGGAGGAAGAAGAGGAAGAAGTTCCTTGGACACAGCATGAATTTGAGTTGGCCCAATGGGCCTTCCGGAAATG GAAGTCTCATCAGTTTACTTCATTACGGGACTTACTCTGGGGCAATGCCGTGTACCTAAAGGAGGCCAATGCCATCAGTGTGGAACTGAA AAAGAAGGTGCAGTTTCAGTTTGTTCTGCTGACTGACACACTGTACTCCCCTTTGCCTCCTGAATTACTTCCCACTGAGATGGAAAAAAC TCATGAGGACAGGCCTTTCCCTCGCACAGTGGTAGCAGTAGAAGTCCAGGATTTGAAGAATGGAGCAACACACTATTGGTCTTTGGAGAA ACTCAAGCAGAGGCTGGATTTGATGCGAGAGATGTATGATAGGGCAGGGGAGATGGCCTCCAGTGCCCAAGACGAAAGCGAAACCACTGT GACTGGCAGCGATCCCTTCTATGATCGGTTCCACTGGTTCAAACTTGTGGGGAGCTCCCCCATTTTCCACGGCTGTGTGAACGAGCGCCT TGCCGACCGCACACCCTCCCCCACTTTTTCCACGGCCGATTCCGACATCACTGAGCTGGCTGACGAGCAGCAAGATGAGATGGAGGATTT TGATGATGAGGCATTCGTGGATGACGCCGGCTCTGACGCAGGGACGGAGGAGGGATCAGATCTCTTCAGTGACGGGCATGACCCGTTTTA CGACCGATCCCCTTGGTTCATTTTAGTGGGAAGGGCATTTGTTTACCTGAGCAATCTGCTGTATCCCGTGCCCCTGATCCACAGGGTGGC CATCGTCAGTGAGAAAGGTGAAGTGCGGGGATTTCTGCGTGTGGCTGTACAGGCCATCGCAGCGGATGAAGAAGCTCCTGATTATGGCTC TGGAATTCGACAGTCAGGAACAGCTAAAATATCTTTTGATAATGAATACTTTAATCAGAGTGACTTTTCGTCTGTTGCAATGACTCGTTC TGGTCTGTCCTTGGAGGAGTTGAGGATTGTGGAAGGACAGGGTCAGAGTTCTGAGGTCATCACTCCTCCAGAAGAAATCAGTCGAATTAA TGACTTGGATTTGAAGTCAAGCACTTTGCTGGATGGTAAGATGGTAATGGAAGGGTTTTCTGAAGAGATTGGCAACCACCTGAAACTGGG CAGTGCCTTCACTTTCCGAGTAACAGTGTTGCAGGCCAGTGGAATCCTCCCAGAGTATGCAGATATCTTCTGTCAGTTCAACTTTTTGCA TCGCCATGATGAAGCATTCTCCACGGAGCCCCTCAAAAACAATGGCAGAGGAAGTCCCCTGGCCTTTTATCATGTGCAGAATATTGCAGT GGAGATCACTGAATCATTTGTGGATTACATCAAAACCAAGCCTATTGTATTTGAAGTCTTTGGGCATTATCAGCAGCACCCACTTCATCT GCAAGGACAGGAGCTTAACAGTCCGCCTCAGCCGTGCCGCCGATTCTTCCCTCCACCCATGCCACTGTCCAAGCCAGTTCCAGCCACCAA GTTAAACACGATGAGCAAAACCAGCCTTGGCCAGAGCATGAGCAAGTATGACCTCCTGGTTTGGTTTGAGATCAGTGAACTGGAGCCTAC AGGAGAGTATATCCCAGCTGTGGTTGACCACACAGCAGGCTTGCCTTGCCAGGGGACATTTTTGCTTCATCAGGGCATCCAGCGAAGGAT CACAGTGACCATTATCCATGAGAAGGGGAGCGAGCTCCATTGGAAAGATGTTCGTGAACTGGTGGTAGGTCGTATTCGGAATAAGCCTGA GGTGGATGAAGCTGCAGTTGATGCCATCCTCTCCCTAAATATTATTTCTGCCAAGTACCTGAAGTCTTCCCACAACTCTAGCAGGACCTT CTACCGCTTTGAGGCTGTGTGGGATAGCTCTCTGCATAACTCCCTTCTTCTGAACCGAGTGACACCCTATGGAGAAAAGATCTACATGAC CTTGTCGGCCTACCTAGAGCTGGATCATTGCATCCAGCCGGCTGTCATCACCAAGGATGTGTGCATGGTCTTCTACTCCCGAGATGCCAA GATCTCACCACCACGCTCTCTGCGTAGCCTCTTTGGCAGCGGCTACTCAAAGTCACCAGATTCGAATCGAGTCACTGGCATTTACGAACT CAGCTTATGCAAAATGTCAGACACAGGTAGTCCAGGTATGCAGAGAAGGAGAAGAAAAATCTTAGATACGTCAGTGGCATATGTGCGGGG AGAAGAGAACTTAGCAGGCTGGCGGCCCCGTGGAGACAGCCTCATCCTTGAGCACCAGTGGGAGCTGGAGAAGCTGGAGCTCCTACATGA GGTGGAAAAAACCCGCCACTTTTTGCTGCTGCGTGAGAGACTTGGTGACAGCATCCCCAAATCCCTGAGCGACTCGTTATCCCCCAGCCT CAGCAGTGGGACCCTCAGCACCTCCACCAGTATCTCCTCTCAGATCTCAACCACTACCTTTGAAAGCGCCATCACACCTAGCGAGAGCAG TGGCTATGATTCAGGAGACATCGAAAGCCTGGTGGACCGAGAGAAAGAGCTGGCTACCAAGTGCCTGCAACTTCTCACCCACACTTTCAA CAGAGAATTCAGCCAGGTGCACGGCAGCGTCAGTGACTGTAAGGTCCAGCCCTGCTGGGAGTTTTCTGCCACACAGATTTGCGGAAGAAC CTGACCGTGGACGAGGGCACCATGAAGGTAGAGGTGCTGCCTGCCCTGACCGACAACTACATGTACCTGGTCATTGATGATGAGACCAAG GAGGCTGCCATTGTGGATCCGGTGCAGCCCCAGAAGGTCGTGGACGCGGCGAGAAAGCACGGGGTGAAACTGACCACAGTGCTCACCACC CACCACCACTGGGACCATGCTGGCGGGAATGAGAAACTGGTCAAGCTGGAGTCGGGACTGAAGGTGTACGGGGGTGACGACCGTATCGGG GCCCTGACTCACAAGATCACTCACCTGTCCACACTGCAGGTGACACCTTGTTTGTGGCTGGCTGCGGGAAGTTCTATGAAGGGACTGCGG ATGAGATGTGTAAAGCTCTGCTGGAGGTCTTGGGCCGGCTCCCCCCGGACACAAGAGTCTACTGTGGCCACGAGTACACCATCAACAACC TCAAGTTTGCACGCCACGTGGAGCCCGGCAATGCCGCCATCCGGGAGAAGCTGGCCTGGGCCAAGGAGAAGTACAGCATCGGGGAGCCCA CAGTGCCATCCACCCTGGCAGAGGAGTTTACCTACAACCCCTTCATGAGAGTGAGGGAGAAGACGGTGCAGCAGCACGCAGGTGAGACGG ACCCGGTGACCACCATGCGGGCCGTGCGCAGGGAGAAGGACCAGTTCAAGATGCCCCGGGACTGAGGCCGCCCTGCACCTTCAGCGGATT TGGGGATTAGGCTCTTTTAGGTAACTGGCTTTCCTGCTGGTCCGTGCGGGAAATTCAGTCTTGATTTAACCTTAATTTTACAGCCCTTGG CTTGTGTTATCGGACATTCTAATGCATATTTATAAGAGAAGTTTAACAAGTATTTATTCCCATAACTTCCCCTTGCAGACTGTTTTCTTC TGGCCTTTAGGCCTCTGCTTGTCCCCTCGGGCCTCCTTCCTCCTCCGTGAGCCACTGCAGTCCCCCCACCCACGCTTCAGGTCAGGCGTG AGCCGGTGCCTTTGCTGTGGCCTTGGCTGGGTGCTGATGGGACTGTCAGGCCCACTGCTGCGGTCGGTACCTTTGCAGCCTGTGCTTGTG >42600_42600_2_KIF1B-HAGH_KIF1B_chr1_10428596_ENST00000377081_HAGH_chr16_1873038_ENST00000455446_length(amino acids)=1636AA_BP=1620 MDCIYIYNKAIKMSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHTSPEDPCFASQNRVYNDIG KEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRV REHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTEKVSKISLVDLAGSERADST GAKGTRLKEGANINKSLTTLGKVISALAEVDNCTSKSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYA DRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDIDPLIDDYSGSGSKYLKDFQNNKHRYLLASENQRPGHFSTASMGS LTSSPSSCSLSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREALLAEMGVAIREDGGTLGVFSP KKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNSGEVIVTLEPCERSETYVNGKRVSQPVQL RSGNRIIMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEILYKKEKEEADLLLEQQRLDYE SKLQALQKQVETRSLAAETTEEEEEEEEVPWTQHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEANAISVELKKKVQFQFVLLTDTL YSPLPPELLPTEMEKTHEDRPFPRTVVAVEVQDLKNGATHYWSLEKLKQRLDLMREMYDRAGEMASSAQDESETTVTGSDPFYDRFHWFK LVGSSPIFHGCVNERLADRTPSPTFSTADSDITELADEQQDEMEDFDDEAFVDDAGSDAGTEEGSDLFSDGHDPFYDRSPWFILVGRAFV YLSNLLYPVPLIHRVAIVSEKGEVRGFLRVAVQAIAADEEAPDYGSGIRQSGTAKISFDNEYFNQSDFSSVAMTRSGLSLEELRIVEGQG QSSEVITPPEEISRINDLDLKSSTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQASGILPEYADIFCQFNFLHRHDEAFSTEPLKNN GRGSPLAFYHVQNIAVEITESFVDYIKTKPIVFEVFGHYQQHPLHLQGQELNSPPQPCRRFFPPPMPLSKPVPATKLNTMSKTSLGQSMS KYDLLVWFEISELEPTGEYIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSELHWKDVRELVVGRIRNKPEVDEAAVDAILSLNI ISAKYLKSSHNSSRTFYRFEAVWDSSLHNSLLLNRVTPYGEKIYMTLSAYLELDHCIQPAVITKDVCMVFYSRDAKISPPRSLRSLFGSG YSKSPDSNRVTGIYELSLCKMSDTGSPGMQRRRRKILDTSVAYVRGEENLAGWRPRGDSLILEHQWELEKLELLHEVEKTRHFLLLRERL GDSIPKSLSDSLSPSLSSGTLSTSTSISSQISTTTFESAITPSESSGYDSGDIESLVDREKELATKCLQLLTHTFNREFSQVHGSVSDCK -------------------------------------------------------------- >42600_42600_3_KIF1B-HAGH_KIF1B_chr1_10428596_ENST00000377086_HAGH_chr16_1873038_ENST00000455446_length(transcript)=6179nt_BP=5026nt GGAGGCTGCTTGAGCAAGCTAGTCATTGTTCATGCAACACAAAACATTCCCGCCCCTAACGCCAGAATGGAGCTTCCAGATCCCTTTTTT TTTTTTTCCTTGATTGCTAAATGAGCTTCCAAGGAAACTTGGCTGTAACTTCAAAAGAAGATTTGATTCTTTATTTCTGGACTGCATATA TATATATAACAAGGCCATTAAAATGTCGGGAGCCTCAGTGAAGGTGGCTGTCCGGGTAAGGCCCTTCAATTCTCGAGAGACCAGCAAGGA ATCCAAATGCATCATTCAGATGCAAGGCAACTCGACCAGTATTATTAACCCAAAGAATCCAAAGGAAGCTCCAAAGTCCTTCAGCTTCGA CTATTCCTACTGGTCTCATACCTCACCCGAAGATCCCTGTTTTGCATCTCAAAACCGTGTGTACAATGACATTGGCAAGGAAATGCTCTT ACACGCCTTTGAGGGATATAATGTCTGTATTTTTGCCTATGGGCAGACTGGTGCTGGAAAATCTTATACAATGATGGGTAAACAAGAAGA AAGCCAGGCTGGCATCATTCCACAGTTATGTGAAGAACTTTTTGAGAAAATCAATGACAACTGTAATGAAGAAATGTCTTACTCTGTAGA GGTGAGCTACATGGAAATTTACTGTGAAAGAGTACGAGATTTGCTGAATCCAAAAAACAAGGGTAATTTGCGTGTGCGTGAACACCCACT TCTTGGACCCTATGTGGAGGATCTGTCCAAGTTGGCAGTTACTTCCTACACAGACATTGCTGACCTCATGGATGCTGGGAACAAAGCCAG GACAGTGGCAGCTACAAACATGAATGAAACAAGTAGCCGTTCCCACGCTGTGTTTACGATTGTTTTCACCCAGAAGAAACACGATAATGA GACCAACCTTTCCACTGAGAAGGTCAGTAAAATCAGCTTGGTGGATCTAGCAGGAAGTGAACGAGCTGATTCAACTGGTGCCAAAGGGAC TCGATTAAAGGAAGGAGCAAATATTAATAAGTCTCTTACAACTTTGGGCAAAGTCATTTCAGCCTTGGCCGAGGTGGATAACTGCACTAG CAAGAGTAAAAAGAAGAAGAAAACAGATTTTATTCCCTACAGGGATTCTGTACTTACTTGGCTCCTTCGAGAAAATTTAGGTGGCAATTC TCGGACTGCAATGGTTGCTGCTCTGAGCCCCGCGGATATCAACTACGATGAGACTTTGAGCACTCTGAGATATGCAGATCGTGCAAAACA AATTAAATGCAATGCTGTTATCAATGAGGACCCCAATGCCAAACTGGTTCGTGAATTAAAGGAGGAGGTGACACGGCTGAAGGACCTTCT TCGTGCTCAGGGCCTGGGAGATATTATTGATATTGATCCATTGATCGATGATTACTCTGGAAGTGGAAGCAAATATCTGAAAGATTTTCA GAACAATAAGCATAGATACTTGCTAGCCTCTGAGAATCAACGCCCTGGCCATTTTTCCACAGCATCCATGGGGTCCCTCACTTCATCCCC ATCTTCCTGCTCACTCAGTAGTCAGGTGGGCTTGACGTCTGTGACCAGTATTCAAGAGAGGATCATGTCTACACCTGGAGGAGAGGAAGC TATTGAACGTTTAAAGGAATCAGAGAAGATCATTGCTGAGTTGAATGAAACTTGGGAAGAGAAGCTTCGTAAAACAGAGGCCATCAGAAT GGAGAGAGAGGCTTTGTTGGCTGAGATGGGAGTTGCCATTCGGGAAGATGGAGGAACCCTAGGGGTTTTCTCACCTAAAAAGACCCCACA TCTTGTTAACCTCAATGAAGACCCACTAATGTCTGAGTGCCTACTTTATTACATCAAAGATGGAATTACAAGGGTTGGCCAAGCAGATGC TGAGCGGCGCCAGGACATAGTGCTGAGCGGGGCTCACATTAAAGAAGAGCATTGTATCTTCCGGAGTGAGAGAAGCAACAGCGGGGAAGT TATCGTGACCTTAGAGCCCTGTGAGCGCTCAGAAACCTACGTAAATGGCAAGAGGGTGTCCCAGCCTGTTCAGCTGCGCTCAGGAAACCG TATCATCATGGGTAAAAACCATGTTTTCCGCTTTAACCACCCGGAACAAGCACGAGCTGAGCGAGAGAAGACTCCTTCTGCTGAGACCCC CTCTGAGCCTGTGGACTGGACATTTGCCCAGAGGGAGCTTCTGGAAAAACAAGGAATTGATATGAAACAAGAGATGGAGAAAAGGCTACA GGAAATGGAGATCTTATACAAAAAGGAGAAGGAAGAAGCAGATCTTCTTTTGGAGCAGCAGAGACTGGACTATGAGAGTAAATTGCAGGC CTTGCAGAAGCAGGTTGAAACCCGATCTCTGGCTGCAGAAACAACTGAAGAGGAGGAAGAAGAGGAAGAAGTTCCTTGGACACAGCATGA ATTTGAGTTGGCCCAATGGGCCTTCCGGAAATGGAAGTCTCATCAGTTTACTTCATTACGGGACTTACTCTGGGGCAATGCCGTGTACCT AAAGGAGGCCAATGCCATCAGTGTGGAACTGAAAAAGAAGGTGCAGTTTCAGTTTGTTCTGCTGACTGACACACTGTACTCCCCTTTGCC TCCTGAATTACTTCCCACTGAGATGGAAAAAACTCATGAGGACAGGCCTTTCCCTCGCACAGTGGTAGCAGTAGAAGTCCAGGATTTGAA GAATGGAGCAACACACTATTGGTCTTTGGAGAAACTCAAGCAGAGGCTGGATTTGATGCGAGAGATGTATGATAGGGCAGGGGAGATGGC CTCCAGTGCCCAAGACGAAAGCGAAACCACTGTGACTGGCAGCGATCCCTTCTATGATCGGTTCCACTGGTTCAAACTTGTGGGGAGCTC CCCCATTTTCCACGGCTGTGTGAACGAGCGCCTTGCCGACCGCACACCCTCCCCCACTTTTTCCACGGCCGATTCCGACATCACTGAGCT GGCTGACGAGCAGCAAGATGAGATGGAGGATTTTGATGATGAGGCATTCGTGGATGACGCCGGCTCTGACGCAGGGACGGAGGAGGGATC AGATCTCTTCAGTGACGGGCATGACCCGTTTTACGACCGATCCCCTTGGTTCATTTTAGTGGGAAGGGCATTTGTTTACCTGAGCAATCT GCTGTATCCCGTGCCCCTGATCCACAGGGTGGCCATCGTCAGTGAGAAAGGTGAAGTGCGGGGATTTCTGCGTGTGGCTGTACAGGCCAT CGCAGCGGATGAAGAAGCTCCTGATTATGGCTCTGGAATTCGACAGTCAGGAACAGCTAAAATATCTTTTGATAATGAATACTTTAATCA GAGTGACTTTTCGTCTGTTGCAATGACTCGTTCTGGTCTGTCCTTGGAGGAGTTGAGGATTGTGGAAGGACAGGGTCAGAGTTCTGAGGT CATCACTCCTCCAGAAGAAATCAGTCGAATTAATGACTTGGATTTGAAGTCAAGCACTTTGCTGGATGGTAAGATGGTAATGGAAGGGTT TTCTGAAGAGATTGGCAACCACCTGAAACTGGGCAGTGCCTTCACTTTCCGAGTAACAGTGTTGCAGGCCAGTGGAATCCTCCCAGAGTA TGCAGATATCTTCTGTCAGTTCAACTTTTTGCATCGCCATGATGAAGCATTCTCCACGGAGCCCCTCAAAAACAATGGCAGAGGAAGTCC CCTGGCCTTTTATCATGTGCAGAATATTGCAGTGGAGATCACTGAATCATTTGTGGATTACATCAAAACCAAGCCTATTGTATTTGAAGT CTTTGGGCATTATCAGCAGCACCCACTTCATCTGCAAGGACAGGAGCTTAACAGTCCGCCTCAGCCGTGCCGCCGATTCTTCCCTCCACC CATGCCACTGTCCAAGCCAGTTCCAGCCACCAAGTTAAACACGATGAGCAAAACCAGCCTTGGCCAGAGCATGAGCAAGTATGACCTCCT GGTTTGGTTTGAGATCAGTGAACTGGAGCCTACAGGAGAGTATATCCCAGCTGTGGTTGACCACACAGCAGGCTTGCCTTGCCAGGGGAC ATTTTTGCTTCATCAGGGCATCCAGCGAAGGATCACAGTGACCATTATCCATGAGAAGGGGAGCGAGCTCCATTGGAAAGATGTTCGTGA ACTGGTGGTAGGTCGTATTCGGAATAAGCCTGAGGTGGATGAAGCTGCAGTTGATGCCATCCTCTCCCTAAATATTATTTCTGCCAAGTA CCTGAAGTCTTCCCACAACTCTAGCAGGACCTTCTACCGCTTTGAGGCTGTGTGGGATAGCTCTCTGCATAACTCCCTTCTTCTGAACCG AGTGACACCCTATGGAGAAAAGATCTACATGACCTTGTCGGCCTACCTAGAGCTGGATCATTGCATCCAGCCGGCTGTCATCACCAAGGA TGTGTGCATGGTCTTCTACTCCCGAGATGCCAAGATCTCACCACCACGCTCTCTGCGTAGCCTCTTTGGCAGCGGCTACTCAAAGTCACC AGATTCGAATCGAGTCACTGGCATTTACGAACTCAGCTTATGCAAAATGTCAGACACAGGTAGTCCAGGTATGCAGAGAAGGAGAAGAAA AATCTTAGATACGTCAGTGGCATATGTGCGGGGAGAAGAGAACTTAGCAGGCTGGCGGCCCCGTGGAGACAGCCTCATCCTTGAGCACCA GTGGGAGCTGGAGAAGCTGGAGCTCCTACATGAGGTGGAAAAAACCCGCCACTTTTTGCTGCTGCGTGAGAGACTTGGTGACAGCATCCC CAAATCCCTGAGCGACTCGTTATCCCCCAGCCTCAGCAGTGGGACCCTCAGCACCTCCACCAGTATCTCCTCTCAGATCTCAACCACTAC CTTTGAAAGCGCCATCACACCTAGCGAGAGCAGTGGCTATGATTCAGGAGACATCGAAAGCCTGGTGGACCGAGAGAAAGAGCTGGCTAC CAAGTGCCTGCAACTTCTCACCCACACTTTCAACAGAGAATTCAGCCAGGTGCACGGCAGCGTCAGTGACTGTAAGGTCCAGCCCTGCTG GGAGTTTTCTGCCACACAGATTTGCGGAAGAACCTGACCGTGGACGAGGGCACCATGAAGGTAGAGGTGCTGCCTGCCCTGACCGACAAC TACATGTACCTGGTCATTGATGATGAGACCAAGGAGGCTGCCATTGTGGATCCGGTGCAGCCCCAGAAGGTCGTGGACGCGGCGAGAAAG CACGGGGTGAAACTGACCACAGTGCTCACCACCCACCACCACTGGGACCATGCTGGCGGGAATGAGAAACTGGTCAAGCTGGAGTCGGGA CTGAAGGTGTACGGGGGTGACGACCGTATCGGGGCCCTGACTCACAAGATCACTCACCTGTCCACACTGCAGGTGACACCTTGTTTGTGG CTGGCTGCGGGAAGTTCTATGAAGGGACTGCGGATGAGATGTGTAAAGCTCTGCTGGAGGTCTTGGGCCGGCTCCCCCCGGACACAAGAG TCTACTGTGGCCACGAGTACACCATCAACAACCTCAAGTTTGCACGCCACGTGGAGCCCGGCAATGCCGCCATCCGGGAGAAGCTGGCCT GGGCCAAGGAGAAGTACAGCATCGGGGAGCCCACAGTGCCATCCACCCTGGCAGAGGAGTTTACCTACAACCCCTTCATGAGAGTGAGGG AGAAGACGGTGCAGCAGCACGCAGGTGAGACGGACCCGGTGACCACCATGCGGGCCGTGCGCAGGGAGAAGGACCAGTTCAAGATGCCCC GGGACTGAGGCCGCCCTGCACCTTCAGCGGATTTGGGGATTAGGCTCTTTTAGGTAACTGGCTTTCCTGCTGGTCCGTGCGGGAAATTCA GTCTTGATTTAACCTTAATTTTACAGCCCTTGGCTTGTGTTATCGGACATTCTAATGCATATTTATAAGAGAAGTTTAACAAGTATTTAT TCCCATAACTTCCCCTTGCAGACTGTTTTCTTCTGGCCTTTAGGCCTCTGCTTGTCCCCTCGGGCCTCCTTCCTCCTCCGTGAGCCACTG CAGTCCCCCCACCCACGCTTCAGGTCAGGCGTGAGCCGGTGCCTTTGCTGTGGCCTTGGCTGGGTGCTGATGGGACTGTCAGGCCCACTG >42600_42600_3_KIF1B-HAGH_KIF1B_chr1_10428596_ENST00000377086_HAGH_chr16_1873038_ENST00000455446_length(amino acids)=1657AA_BP=1641 MLNELPRKLGCNFKRRFDSLFLDCIYIYNKAIKMSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYW SHTSPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQAGIIPQLCEELFEKINDNCNEEMSYSVEVSYM EIYCERVRDLLNPKNKGNLRVREHPLLGPYVEDLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLS TEKVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVDNCTSKSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAM VAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGLGDIIDIDPLIDDYSGSGSKYLKDFQNNKH RYLLASENQRPGHFSTASMGSLTSSPSSCSLSSQVGLTSVTSIQERIMSTPGGEEAIERLKESEKIIAELNETWEEKLRKTEAIRMEREA LLAEMGVAIREDGGTLGVFSPKKTPHLVNLNEDPLMSECLLYYIKDGITRVGQADAERRQDIVLSGAHIKEEHCIFRSERSNSGEVIVTL EPCERSETYVNGKRVSQPVQLRSGNRIIMGKNHVFRFNHPEQARAEREKTPSAETPSEPVDWTFAQRELLEKQGIDMKQEMEKRLQEMEI LYKKEKEEADLLLEQQRLDYESKLQALQKQVETRSLAAETTEEEEEEEEVPWTQHEFELAQWAFRKWKSHQFTSLRDLLWGNAVYLKEAN AISVELKKKVQFQFVLLTDTLYSPLPPELLPTEMEKTHEDRPFPRTVVAVEVQDLKNGATHYWSLEKLKQRLDLMREMYDRAGEMASSAQ DESETTVTGSDPFYDRFHWFKLVGSSPIFHGCVNERLADRTPSPTFSTADSDITELADEQQDEMEDFDDEAFVDDAGSDAGTEEGSDLFS DGHDPFYDRSPWFILVGRAFVYLSNLLYPVPLIHRVAIVSEKGEVRGFLRVAVQAIAADEEAPDYGSGIRQSGTAKISFDNEYFNQSDFS SVAMTRSGLSLEELRIVEGQGQSSEVITPPEEISRINDLDLKSSTLLDGKMVMEGFSEEIGNHLKLGSAFTFRVTVLQASGILPEYADIF CQFNFLHRHDEAFSTEPLKNNGRGSPLAFYHVQNIAVEITESFVDYIKTKPIVFEVFGHYQQHPLHLQGQELNSPPQPCRRFFPPPMPLS KPVPATKLNTMSKTSLGQSMSKYDLLVWFEISELEPTGEYIPAVVDHTAGLPCQGTFLLHQGIQRRITVTIIHEKGSELHWKDVRELVVG RIRNKPEVDEAAVDAILSLNIISAKYLKSSHNSSRTFYRFEAVWDSSLHNSLLLNRVTPYGEKIYMTLSAYLELDHCIQPAVITKDVCMV FYSRDAKISPPRSLRSLFGSGYSKSPDSNRVTGIYELSLCKMSDTGSPGMQRRRRKILDTSVAYVRGEENLAGWRPRGDSLILEHQWELE KLELLHEVEKTRHFLLLRERLGDSIPKSLSDSLSPSLSSGTLSTSTSISSQISTTTFESAITPSESSGYDSGDIESLVDREKELATKCLQ -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for KIF1B-HAGH |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000263934 | + | 42 | 47 | 270_350 | 1562.0 | 1771.0 | KBP |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377081 | + | 43 | 48 | 270_350 | 1608.0 | 1824.0 | KBP |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377086 | + | 44 | 49 | 270_350 | 1608.0 | 1817.0 | KBP |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377083 | + | 1 | 21 | 270_350 | 0 | 1154.0 | KBP |
| Hgene | KIF1B | chr1:10428596 | chr16:1873038 | ENST00000377093 | + | 1 | 21 | 270_350 | 0 | 1154.0 | KBP |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for KIF1B-HAGH |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for KIF1B-HAGH |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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