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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KIF5B-RET (FusionGDB2 ID:42734)

Fusion Gene Summary for KIF5B-RET

check button Fusion gene summary
Fusion gene informationFusion gene name: KIF5B-RET
Fusion gene ID: 42734
HgeneTgene
Gene symbol

KIF5B

RET

Gene ID

3799

5979

Gene namekinesin family member 5Bret proto-oncogene
SynonymsHEL-S-61|KINH|KNS|KNS1|UKHCCDHF12|CDHR16|HSCR1|MEN2A|MEN2B|MTC1|PTC|RET-ELE1
Cytomap

10p11.22

10q11.21

Type of geneprotein-codingprotein-coding
Descriptionkinesin-1 heavy chainconventional kinesin heavy chainepididymis secretory protein Li 61kinesin 1 (110-120kD)kinesin heavy chainubiquitous kinesin heavy chainproto-oncogene tyrosine-protein kinase receptor RetRET receptor tyrosine kinasecadherin family member 12cadherin-related family member 16proto-oncogene c-Retrearranged during transfectionret proto-oncogene (multiple endocrine neoplasia and medullary
Modification date2020031320200322
UniProtAcc

P33176

RTL1

Ensembl transtripts involved in fusion geneENST00000493889, ENST00000302418, 
ENST00000340058, ENST00000355710, 
Fusion gene scores* DoF score12 X 17 X 10=204032 X 31 X 11=10912
# samples 2248
** MAII scorelog2(22/2040*10)=-3.2129937233342
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(48/10912*10)=-4.50673733341565
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KIF5B [Title/Abstract] AND RET [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKIF5B(32317355)-RET(43612030), # samples:5
Anticipated loss of major functional domain due to fusion event.KIF5B-RET seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
KIF5B-RET seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
KIF5B-RET seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
KIF5B-RET seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKIF5B

GO:0042391

regulation of membrane potential

19675065

HgeneKIF5B

GO:0043268

positive regulation of potassium ion transport

19675065

HgeneKIF5B

GO:0047496

vesicle transport along microtubule

28426968

HgeneKIF5B

GO:1903078

positive regulation of protein localization to plasma membrane

19675065

TgeneRET

GO:0030155

regulation of cell adhesion

21357690

TgeneRET

GO:0030335

positive regulation of cell migration

20702524

TgeneRET

GO:0033619

membrane protein proteolysis

21357690

TgeneRET

GO:0033630

positive regulation of cell adhesion mediated by integrin

20702524

TgeneRET

GO:0035860

glial cell-derived neurotrophic factor receptor signaling pathway

28953886

TgeneRET

GO:0043410

positive regulation of MAPK cascade

28846099


check buttonFusion gene breakpoints across KIF5B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RET (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerKB3..KIF5Bchr10

32311775

-RETchr10

43612031

+
ChimerKB3..KIF5Bchr10

32345110

-RETchr10

43609927

+
ChimerKB3..KIF5Bchr10

32345110

-RETchr10

43612030

+
ChimerKB3..KIF5Bchr10

32345110

-RETchr10

43612032

+
ChimerKB3..KIF5Bchr10

32345371

-RETchr10

43607546

+
ChimerKB3..KIF5Bchr10

32345371

-RETchr10

43612030

+
ChimerKB3..KIF5Bchr10

32345371

-RETchr10

43612032

+
ChimerKB4..KIF5Bchr10

32311775

-RETchr10

43612031

+
ChimerKB4..KIF5Bchr10

32317499

-RETchr10

32317499

+
ChiTaRS5.0N/AAB795249KIF5Bchr10

32317355

-RETchr10

43612030

+
ChiTaRS5.0N/AAB795250KIF5Bchr10

32317355

-RETchr10

43612030

+
ChiTaRS5.0N/AAB795251KIF5Bchr10

32311775

-RETchr10

43612032

+
ChiTaRS5.0N/AAB795252KIF5Bchr10

32311775

-RETchr10

43612032

+
ChiTaRS5.0N/AAB795253KIF5Bchr10

32307243

-RETchr10

43612030

+
ChiTaRS5.0N/AAB795254KIF5Bchr10

32307243

-RETchr10

43612030

+
ChiTaRS5.0N/AAB795255KIF5Bchr10

32306979

-RETchr10

43612030

+
ChiTaRS5.0N/AAB795256KIF5Bchr10

32306979

-RETchr10

43612030

+
ChiTaRS5.0N/AAB795257KIF5Bchr10

32306071

-RETchr10

43609927

+
ChiTaRS5.0N/AHW088349KIF5Bchr10

32317355

-RETchr10

43612030

+
ChiTaRS5.0N/AHW088350KIF5Bchr10

32311775

-RETchr10

43612032

+
ChiTaRS5.0N/AHW088351KIF5Bchr10

32306979

-RETchr10

43612030

+
ChiTaRS5.0N/AHW088352KIF5Bchr10

32306071

-RETchr10

43607546

+
ChiTaRS5.0N/AJB417295KIF5Bchr10

32317355

-RETchr10

43612030

+
ChiTaRS5.0N/AJB417297KIF5Bchr10

32317355

-RETchr10

43612030

+


Top

Fusion Gene ORF analysis for KIF5B-RET

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5UTR-3CDSENST00000493889ENST00000340058KIF5Bchr10

32306979

-RETchr10

43612030

+
5UTR-3CDSENST00000493889ENST00000355710KIF5Bchr10

32306979

-RETchr10

43612030

+
Frame-shiftENST00000302418ENST00000340058KIF5Bchr10

32306071

-RETchr10

43609927

+
Frame-shiftENST00000302418ENST00000340058KIF5Bchr10

32306071

-RETchr10

43607546

+
Frame-shiftENST00000302418ENST00000355710KIF5Bchr10

32306071

-RETchr10

43609927

+
Frame-shiftENST00000302418ENST00000355710KIF5Bchr10

32306071

-RETchr10

43607546

+
In-frameENST00000302418ENST00000340058KIF5Bchr10

32311775

-RETchr10

43612031

+
In-frameENST00000302418ENST00000340058KIF5Bchr10

32317355

-RETchr10

43612030

+
In-frameENST00000302418ENST00000340058KIF5Bchr10

32311775

-RETchr10

43612032

+
In-frameENST00000302418ENST00000340058KIF5Bchr10

32307243

-RETchr10

43612030

+
In-frameENST00000302418ENST00000340058KIF5Bchr10

32306979

-RETchr10

43612030

+
In-frameENST00000302418ENST00000355710KIF5Bchr10

32311775

-RETchr10

43612031

+
In-frameENST00000302418ENST00000355710KIF5Bchr10

32317355

-RETchr10

43612030

+
In-frameENST00000302418ENST00000355710KIF5Bchr10

32311775

-RETchr10

43612032

+
In-frameENST00000302418ENST00000355710KIF5Bchr10

32307243

-RETchr10

43612030

+
In-frameENST00000302418ENST00000355710KIF5Bchr10

32306979

-RETchr10

43612030

+
intron-3CDSENST00000302418ENST00000340058KIF5Bchr10

32345110

-RETchr10

43609927

+
intron-3CDSENST00000302418ENST00000340058KIF5Bchr10

32345110

-RETchr10

43612030

+
intron-3CDSENST00000302418ENST00000340058KIF5Bchr10

32345110

-RETchr10

43612032

+
intron-3CDSENST00000302418ENST00000340058KIF5Bchr10

32345371

-RETchr10

43607546

+
intron-3CDSENST00000302418ENST00000340058KIF5Bchr10

32345371

-RETchr10

43612030

+
intron-3CDSENST00000302418ENST00000340058KIF5Bchr10

32345371

-RETchr10

43612032

+
intron-3CDSENST00000302418ENST00000355710KIF5Bchr10

32345110

-RETchr10

43609927

+
intron-3CDSENST00000302418ENST00000355710KIF5Bchr10

32345110

-RETchr10

43612030

+
intron-3CDSENST00000302418ENST00000355710KIF5Bchr10

32345110

-RETchr10

43612032

+
intron-3CDSENST00000302418ENST00000355710KIF5Bchr10

32345371

-RETchr10

43607546

+
intron-3CDSENST00000302418ENST00000355710KIF5Bchr10

32345371

-RETchr10

43612030

+
intron-3CDSENST00000302418ENST00000355710KIF5Bchr10

32345371

-RETchr10

43612032

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32311775

-RETchr10

43612031

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32345110

-RETchr10

43609927

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32345110

-RETchr10

43612030

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32345110

-RETchr10

43612032

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32345371

-RETchr10

43607546

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32345371

-RETchr10

43612030

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32345371

-RETchr10

43612032

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32317355

-RETchr10

43612030

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32311775

-RETchr10

43612032

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32307243

-RETchr10

43612030

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32306071

-RETchr10

43609927

+
intron-3CDSENST00000493889ENST00000340058KIF5Bchr10

32306071

-RETchr10

43607546

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32311775

-RETchr10

43612031

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32345110

-RETchr10

43609927

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32345110

-RETchr10

43612030

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32345110

-RETchr10

43612032

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32345371

-RETchr10

43607546

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32345371

-RETchr10

43612030

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32345371

-RETchr10

43612032

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32317355

-RETchr10

43612030

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32311775

-RETchr10

43612032

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32307243

-RETchr10

43612030

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32306071

-RETchr10

43609927

+
intron-3CDSENST00000493889ENST00000355710KIF5Bchr10

32306071

-RETchr10

43607546

+
intron-intronENST00000302418ENST00000340058KIF5Bchr10

32317499

-RETchr10

32317499

+
intron-intronENST00000302418ENST00000355710KIF5Bchr10

32317499

-RETchr10

32317499

+
intron-intronENST00000493889ENST00000340058KIF5Bchr10

32317499

-RETchr10

32317499

+
intron-intronENST00000493889ENST00000355710KIF5Bchr10

32317499

-RETchr10

32317499

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000302418KIF5Bchr1032311775-ENST00000355710RETchr1043612031+5663237245835801040
ENST00000302418KIF5Bchr1032311775-ENST00000340058RETchr1043612031+420523724583454998
ENST00000302418KIF5Bchr1032317355-ENST00000355710RETchr1043612030+547421834583391977
ENST00000302418KIF5Bchr1032317355-ENST00000340058RETchr1043612030+401621834583265935
ENST00000302418KIF5Bchr1032311775-ENST00000355710RETchr1043612032+5663237245835801040
ENST00000302418KIF5Bchr1032311775-ENST00000340058RETchr1043612032+420523724583454998
ENST00000302418KIF5Bchr1032307243-ENST00000355710RETchr1043612030+6188289745841051215
ENST00000302418KIF5Bchr1032307243-ENST00000340058RETchr1043612030+4730289745839791173
ENST00000302418KIF5Bchr1032306979-ENST00000355710RETchr1043612030+6293300245842101250
ENST00000302418KIF5Bchr1032306979-ENST00000340058RETchr1043612030+4835300245840841208

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000302418ENST00000355710KIF5Bchr1032317355-RETchr1043612030+0.0006691350.9993309
ENST00000302418ENST00000340058KIF5Bchr1032317355-RETchr1043612030+0.0018744570.9981255
ENST00000302418ENST00000355710KIF5Bchr1032311775-RETchr1043612032+0.0008882590.9991117
ENST00000302418ENST00000340058KIF5Bchr1032311775-RETchr1043612032+0.0025218490.9974782
ENST00000302418ENST00000355710KIF5Bchr1032307243-RETchr1043612030+0.0006394850.9993605
ENST00000302418ENST00000340058KIF5Bchr1032307243-RETchr1043612030+0.0020556030.9979444
ENST00000302418ENST00000355710KIF5Bchr1032306979-RETchr1043612030+0.0008586990.99914134
ENST00000302418ENST00000340058KIF5Bchr1032306979-RETchr1043612030+0.0033660140.99663395

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Fusion Genomic Features for KIF5B-RET


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KIF5Bchr1032306070-RETchr1043607546+0.96750240.032497503
KIF5Bchr1032306070-RETchr1043609927+0.037381870.9626182
KIF5Bchr1032311775-RETchr1043612031+0.024187050.9758129
KIF5Bchr1032307243-RETchr1043612031+2.55E-050.9999745
KIF5Bchr1032306979-RETchr1043612031+1.77E-060.9999982
KIF5Bchr1032317355-RETchr1043612031+2.39E-091
KIF5Bchr1032306070-RETchr1043607546+0.96750240.032497503
KIF5Bchr1032306070-RETchr1043609927+0.037381870.9626182
KIF5Bchr1032311775-RETchr1043612031+0.024187050.9758129
KIF5Bchr1032307243-RETchr1043612031+2.55E-050.9999745
KIF5Bchr1032306979-RETchr1043612031+1.77E-060.9999982
KIF5Bchr1032317355-RETchr1043612031+2.39E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for KIF5B-RET


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr10:32317355/chr10:43612030)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KIF5B

P33176

RET

RTL1

FUNCTION: Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner (By similarity). Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation (By similarity). Through binding with PLEKHM2 and ARL8B, directs lysosome movement toward microtubule plus ends (Probable). Involved in NK cell-mediated cytotoxicity. Drives the polarization of cytolytic granules and microtubule-organizing centers (MTOCs) toward the immune synapse between effector NK lymphocytes and target cells (PubMed:24088571). {ECO:0000250|UniProtKB:Q2PQA9, ECO:0000250|UniProtKB:Q61768, ECO:0000269|PubMed:20386726, ECO:0000269|PubMed:24088571, ECO:0000305|PubMed:22172677, ECO:0000305|PubMed:24088571}.1358

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIF5Bchr10:32306979chr10:43612030ENST00000302418-23268_3258481626.0DomainKinesin motor
HgeneKIF5Bchr10:32307243chr10:43612030ENST00000302418-22268_3258131626.0DomainKinesin motor
HgeneKIF5Bchr10:32311775chr10:43612032ENST00000302418-16268_3256381626.0DomainKinesin motor
HgeneKIF5Bchr10:32317355chr10:43612030ENST00000302418-15268_3255751626.0DomainKinesin motor
HgeneKIF5Bchr10:32306979chr10:43612030ENST00000302418-232685_928481626.0Nucleotide bindingNote=ATP
HgeneKIF5Bchr10:32307243chr10:43612030ENST00000302418-222685_928131626.0Nucleotide bindingNote=ATP
HgeneKIF5Bchr10:32311775chr10:43612032ENST00000302418-162685_926381626.0Nucleotide bindingNote=ATP
HgeneKIF5Bchr10:32317355chr10:43612030ENST00000302418-152685_925751626.0Nucleotide bindingNote=ATP
TgeneRETchr10:32306979chr10:43612030ENST000003400581019724_10167121073.0DomainProtein kinase
TgeneRETchr10:32306979chr10:43612030ENST000003557101020724_10167121115.0DomainProtein kinase
TgeneRETchr10:32307243chr10:43612030ENST000003400581019724_10167121073.0DomainProtein kinase
TgeneRETchr10:32307243chr10:43612030ENST000003557101020724_10167121115.0DomainProtein kinase
TgeneRETchr10:32311775chr10:43612032ENST000003400581019724_10167121073.0DomainProtein kinase
TgeneRETchr10:32311775chr10:43612032ENST000003557101020724_10167121115.0DomainProtein kinase
TgeneRETchr10:32317355chr10:43612030ENST000003400581019724_10167121073.0DomainProtein kinase
TgeneRETchr10:32317355chr10:43612030ENST000003557101020724_10167121115.0DomainProtein kinase
TgeneRETchr10:32306979chr10:43612030ENST000003400581019730_7387121073.0Nucleotide bindingATP
TgeneRETchr10:32306979chr10:43612030ENST000003557101020730_7387121115.0Nucleotide bindingATP
TgeneRETchr10:32307243chr10:43612030ENST000003400581019730_7387121073.0Nucleotide bindingATP
TgeneRETchr10:32307243chr10:43612030ENST000003557101020730_7387121115.0Nucleotide bindingATP
TgeneRETchr10:32311775chr10:43612032ENST000003400581019730_7387121073.0Nucleotide bindingATP
TgeneRETchr10:32311775chr10:43612032ENST000003557101020730_7387121115.0Nucleotide bindingATP
TgeneRETchr10:32317355chr10:43612030ENST000003400581019730_7387121073.0Nucleotide bindingATP
TgeneRETchr10:32317355chr10:43612030ENST000003557101020730_7387121115.0Nucleotide bindingATP
TgeneRETchr10:32306979chr10:43612030ENST000003400581019805_8077121073.0RegionNote=Inhibitors binding
TgeneRETchr10:32306979chr10:43612030ENST000003557101020805_8077121115.0RegionNote=Inhibitors binding
TgeneRETchr10:32307243chr10:43612030ENST000003400581019805_8077121073.0RegionNote=Inhibitors binding
TgeneRETchr10:32307243chr10:43612030ENST000003557101020805_8077121115.0RegionNote=Inhibitors binding
TgeneRETchr10:32311775chr10:43612032ENST000003400581019805_8077121073.0RegionNote=Inhibitors binding
TgeneRETchr10:32311775chr10:43612032ENST000003557101020805_8077121115.0RegionNote=Inhibitors binding
TgeneRETchr10:32317355chr10:43612030ENST000003400581019805_8077121073.0RegionNote=Inhibitors binding
TgeneRETchr10:32317355chr10:43612030ENST000003557101020805_8077121115.0RegionNote=Inhibitors binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKIF5Bchr10:32306979chr10:43612030ENST00000302418-2326329_9148481626.0Coiled coil.
HgeneKIF5Bchr10:32307243chr10:43612030ENST00000302418-2226329_9148131626.0Coiled coil.
HgeneKIF5Bchr10:32311775chr10:43612032ENST00000302418-1626329_9146381626.0Coiled coil.
HgeneKIF5Bchr10:32317355chr10:43612030ENST00000302418-1526329_9145751626.0Coiled coil.
HgeneKIF5Bchr10:32306979chr10:43612030ENST00000302418-2326915_9638481626.0RegionNote=Globular
HgeneKIF5Bchr10:32307243chr10:43612030ENST00000302418-2226915_9638131626.0RegionNote=Globular
HgeneKIF5Bchr10:32311775chr10:43612032ENST00000302418-1626915_9636381626.0RegionNote=Globular
HgeneKIF5Bchr10:32317355chr10:43612030ENST00000302418-1526915_9635751626.0RegionNote=Globular
TgeneRETchr10:32306979chr10:43612030ENST000003400581019168_2727121073.0DomainCadherin
TgeneRETchr10:32306979chr10:43612030ENST000003557101020168_2727121115.0DomainCadherin
TgeneRETchr10:32307243chr10:43612030ENST000003400581019168_2727121073.0DomainCadherin
TgeneRETchr10:32307243chr10:43612030ENST000003557101020168_2727121115.0DomainCadherin
TgeneRETchr10:32311775chr10:43612032ENST000003400581019168_2727121073.0DomainCadherin
TgeneRETchr10:32311775chr10:43612032ENST000003557101020168_2727121115.0DomainCadherin
TgeneRETchr10:32317355chr10:43612030ENST000003400581019168_2727121073.0DomainCadherin
TgeneRETchr10:32317355chr10:43612030ENST000003557101020168_2727121115.0DomainCadherin
TgeneRETchr10:32306979chr10:43612030ENST00000340058101929_6357121073.0Topological domainExtracellular
TgeneRETchr10:32306979chr10:43612030ENST000003400581019658_11147121073.0Topological domainCytoplasmic
TgeneRETchr10:32306979chr10:43612030ENST00000355710102029_6357121115.0Topological domainExtracellular
TgeneRETchr10:32306979chr10:43612030ENST000003557101020658_11147121115.0Topological domainCytoplasmic
TgeneRETchr10:32307243chr10:43612030ENST00000340058101929_6357121073.0Topological domainExtracellular
TgeneRETchr10:32307243chr10:43612030ENST000003400581019658_11147121073.0Topological domainCytoplasmic
TgeneRETchr10:32307243chr10:43612030ENST00000355710102029_6357121115.0Topological domainExtracellular
TgeneRETchr10:32307243chr10:43612030ENST000003557101020658_11147121115.0Topological domainCytoplasmic
TgeneRETchr10:32311775chr10:43612032ENST00000340058101929_6357121073.0Topological domainExtracellular
TgeneRETchr10:32311775chr10:43612032ENST000003400581019658_11147121073.0Topological domainCytoplasmic
TgeneRETchr10:32311775chr10:43612032ENST00000355710102029_6357121115.0Topological domainExtracellular
TgeneRETchr10:32311775chr10:43612032ENST000003557101020658_11147121115.0Topological domainCytoplasmic
TgeneRETchr10:32317355chr10:43612030ENST00000340058101929_6357121073.0Topological domainExtracellular
TgeneRETchr10:32317355chr10:43612030ENST000003400581019658_11147121073.0Topological domainCytoplasmic
TgeneRETchr10:32317355chr10:43612030ENST00000355710102029_6357121115.0Topological domainExtracellular
TgeneRETchr10:32317355chr10:43612030ENST000003557101020658_11147121115.0Topological domainCytoplasmic
TgeneRETchr10:32306979chr10:43612030ENST000003400581019636_6577121073.0TransmembraneHelical
TgeneRETchr10:32306979chr10:43612030ENST000003557101020636_6577121115.0TransmembraneHelical
TgeneRETchr10:32307243chr10:43612030ENST000003400581019636_6577121073.0TransmembraneHelical
TgeneRETchr10:32307243chr10:43612030ENST000003557101020636_6577121115.0TransmembraneHelical
TgeneRETchr10:32311775chr10:43612032ENST000003400581019636_6577121073.0TransmembraneHelical
TgeneRETchr10:32311775chr10:43612032ENST000003557101020636_6577121115.0TransmembraneHelical
TgeneRETchr10:32317355chr10:43612030ENST000003400581019636_6577121073.0TransmembraneHelical
TgeneRETchr10:32317355chr10:43612030ENST000003557101020636_6577121115.0TransmembraneHelical


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Fusion Gene Sequence for KIF5B-RET


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42734_42734_1_KIF5B-RET_KIF5B_chr10_32306979_ENST00000302418_RET_chr10_43612030_ENST00000340058_length(transcript)=4835nt_BP=3002nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGCAGCCTGAGGGAACTGGCATGATAGATGAAGAGTTCACTGTTGCAAGACTCTACATTAGCAAAATGA
AGTCAGAAGTAAAAACCATGGTGAAACGTTGCAAGCAGTTAGAAAGCACACAAACTGAGAGCAACAAAAAAATGGAAGAAAATGAAAAGG
AGTTAGCAGCATGTCAGCTTCGTATCTCTCAACATGAAGCCAAAATCAAGTCATTGACTGAATACCTTCAAAATGTGGAACAAAAGAAAA
GACAGTTGGAGGAATCTGTCGATGCCCTCAGTGAAGAACTAGTCCAGCTTCGAGCACAAGAGAAAGTCCATGAAATGGAAAAGGAGCACT
TAAATAAGGTTCAGACTGCAAATGAAGTTAAGCAAGCTGTTGAACAGCAGATCCAGAGCCATAGAGAAACTCATCAAAAACAGATCAGTA
GTTTGAGAGATGAAGTAGAAGCAAAAGCAAAACTTATTACTGATCTTCAAGACCAAAACCAGAAAATGATGTTAGAGCAGGAACGTCTAA
GAGTAGAACATGAGAAGTTGAAAGCCACAGATCAGGAAAAGAGCAGAAAACTACATGAACTTACGGTTATGCAAGATAGACGAGAACAAG
CAAGACAAGACTTGAAGGGTTTGGAAGAGACAGTGGCAAAAGAACTTCAGACTTTACACAACCTGCGCAAACTCTTTGTTCAGGACCTGG
CTACAAGAGTTAAAAAGAGTGCTGAGATTGATTCTGATGACACCGGAGGCAGCGCTGCTCAGAAGCAAAAAATCTCCTTTCTTGAAAATA
ATCTTGAACAGCTCACTAAAGTGCACAAACAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAG
AAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAG
AGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATG
GGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAG
TGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCA
TCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGG
TAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTC
GGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGT
GGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGA
GGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCA
GCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACG
GCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCT
ATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCTTTTTAAAAATGTT
TCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTTAGGCATTATTGCA
ACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAAACAGATCAGGGCG
GAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTTAACTAAGTGGATA
AATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCAGGTTCCCCCAGAC
CCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGTCCCAGCCACATGT
CCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCTTTCCCTTACCCAC
CTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTGCTGTGGTCTTACA

>42734_42734_1_KIF5B-RET_KIF5B_chr10_32306979_ENST00000302418_RET_chr10_43612030_ENST00000340058_length(amino acids)=1208AA_BP=848
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELA
ACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLR
DEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATR
VKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENA
SPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISF
AWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEI
VTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLS

--------------------------------------------------------------
>42734_42734_2_KIF5B-RET_KIF5B_chr10_32306979_ENST00000302418_RET_chr10_43612030_ENST00000355710_length(transcript)=6293nt_BP=3002nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGCAGCCTGAGGGAACTGGCATGATAGATGAAGAGTTCACTGTTGCAAGACTCTACATTAGCAAAATGA
AGTCAGAAGTAAAAACCATGGTGAAACGTTGCAAGCAGTTAGAAAGCACACAAACTGAGAGCAACAAAAAAATGGAAGAAAATGAAAAGG
AGTTAGCAGCATGTCAGCTTCGTATCTCTCAACATGAAGCCAAAATCAAGTCATTGACTGAATACCTTCAAAATGTGGAACAAAAGAAAA
GACAGTTGGAGGAATCTGTCGATGCCCTCAGTGAAGAACTAGTCCAGCTTCGAGCACAAGAGAAAGTCCATGAAATGGAAAAGGAGCACT
TAAATAAGGTTCAGACTGCAAATGAAGTTAAGCAAGCTGTTGAACAGCAGATCCAGAGCCATAGAGAAACTCATCAAAAACAGATCAGTA
GTTTGAGAGATGAAGTAGAAGCAAAAGCAAAACTTATTACTGATCTTCAAGACCAAAACCAGAAAATGATGTTAGAGCAGGAACGTCTAA
GAGTAGAACATGAGAAGTTGAAAGCCACAGATCAGGAAAAGAGCAGAAAACTACATGAACTTACGGTTATGCAAGATAGACGAGAACAAG
CAAGACAAGACTTGAAGGGTTTGGAAGAGACAGTGGCAAAAGAACTTCAGACTTTACACAACCTGCGCAAACTCTTTGTTCAGGACCTGG
CTACAAGAGTTAAAAAGAGTGCTGAGATTGATTCTGATGACACCGGAGGCAGCGCTGCTCAGAAGCAAAAAATCTCCTTTCTTGAAAATA
ATCTTGAACAGCTCACTAAAGTGCACAAACAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAG
AAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAG
AGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATG
GGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAG
TGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCA
TCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGG
TAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTC
GGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGT
GGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGA
GGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCA
GCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACG
GCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCT
ATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCAA
ATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTCTTTGTGAAAGGTA
ATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCGAGCCGTGTTCAGT
TCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTCCCTCCTAGCAGAC
ATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGTTGGTCTGTGTCCA
TCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAACTGTTGGATTTTTC
TAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCCCTGATGACCTGTC
CTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGGCCCCGAGGATGGG
CCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTTTCATCATGATTAA
GATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGGCTCACAAGACACA
TTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGAAGAAAGGGGGCTG
TTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCACAGCCAAGTAGAG
GCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTACTCATAAAGGGAC
AGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGAAAAAGATGGTGTT
TGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATGTTTCTGTTTCTTA
GATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCAGTCTTGTGGGGGC
AGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCAAAACACTGCCTGC
TCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAAACAGCAAAATTGT
GGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAGTTTGAAAAATGCT
TATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATAGACATGGTAAACT
TTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAATGCCTACACAGTAA
GTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAATTTATCCTTGACC
AATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAATTTTCATACACGTA
AATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCTATTTATGAAAGGT

>42734_42734_2_KIF5B-RET_KIF5B_chr10_32306979_ENST00000302418_RET_chr10_43612030_ENST00000355710_length(amino acids)=1250AA_BP=848
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELA
ACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLR
DEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATR
VKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENA
SPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISF
AWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEI
VTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLS

--------------------------------------------------------------
>42734_42734_3_KIF5B-RET_KIF5B_chr10_32307243_ENST00000302418_RET_chr10_43612030_ENST00000340058_length(transcript)=4730nt_BP=2897nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGCAGCCTGAGGGAACTGGCATGATAGATGAAGAGTTCACTGTTGCAAGACTCTACATTAGCAAAATGA
AGTCAGAAGTAAAAACCATGGTGAAACGTTGCAAGCAGTTAGAAAGCACACAAACTGAGAGCAACAAAAAAATGGAAGAAAATGAAAAGG
AGTTAGCAGCATGTCAGCTTCGTATCTCTCAACATGAAGCCAAAATCAAGTCATTGACTGAATACCTTCAAAATGTGGAACAAAAGAAAA
GACAGTTGGAGGAATCTGTCGATGCCCTCAGTGAAGAACTAGTCCAGCTTCGAGCACAAGAGAAAGTCCATGAAATGGAAAAGGAGCACT
TAAATAAGGTTCAGACTGCAAATGAAGTTAAGCAAGCTGTTGAACAGCAGATCCAGAGCCATAGAGAAACTCATCAAAAACAGATCAGTA
GTTTGAGAGATGAAGTAGAAGCAAAAGCAAAACTTATTACTGATCTTCAAGACCAAAACCAGAAAATGATGTTAGAGCAGGAACGTCTAA
GAGTAGAACATGAGAAGTTGAAAGCCACAGATCAGGAAAAGAGCAGAAAACTACATGAACTTACGGTTATGCAAGATAGACGAGAACAAG
CAAGACAAGACTTGAAGGGTTTGGAAGAGACAGTGGCAAAAGAACTTCAGACTTTACACAACCTGCGCAAACTCTTTGTTCAGGACCTGG
CTACAAGAGTTAAAAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAA
AAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGA
GTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGG
ATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACC
TGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGC
AGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGA
AGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAAT
GGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCC
TAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCA
GCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGA
AGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGG
AGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGTAGAATTTCCC
ATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCTTTTTAAAAATGTTTCTGGTCTGAACAAA
ACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTTAGGCATTATTGCAACTATGTTTTTCTAA
AAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAAACAGATCAGGGCGGAACTCTCAGGGGAG
ACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTTAACTAAGTGGATAAATATACAAATCTGG
GGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCAGGTTCCCCCAGACCCCTCCTGGGCAGGC
AGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGTCCCAGCCACATGTCCTCCATCAGGGGTA
GCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCTTTCCCTTACCCACCTTCAGGACGGTTGT
CACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTGCTGTGGTCTTACAATGGACAGTAAATAT

>42734_42734_3_KIF5B-RET_KIF5B_chr10_32307243_ENST00000302418_RET_chr10_43612030_ENST00000340058_length(amino acids)=1173AA_BP=813
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELA
ACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLR
DEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATR
VKKEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGP
LLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMK
ISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEE
MYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGRISHAF

--------------------------------------------------------------
>42734_42734_4_KIF5B-RET_KIF5B_chr10_32307243_ENST00000302418_RET_chr10_43612030_ENST00000355710_length(transcript)=6188nt_BP=2897nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGCAGCCTGAGGGAACTGGCATGATAGATGAAGAGTTCACTGTTGCAAGACTCTACATTAGCAAAATGA
AGTCAGAAGTAAAAACCATGGTGAAACGTTGCAAGCAGTTAGAAAGCACACAAACTGAGAGCAACAAAAAAATGGAAGAAAATGAAAAGG
AGTTAGCAGCATGTCAGCTTCGTATCTCTCAACATGAAGCCAAAATCAAGTCATTGACTGAATACCTTCAAAATGTGGAACAAAAGAAAA
GACAGTTGGAGGAATCTGTCGATGCCCTCAGTGAAGAACTAGTCCAGCTTCGAGCACAAGAGAAAGTCCATGAAATGGAAAAGGAGCACT
TAAATAAGGTTCAGACTGCAAATGAAGTTAAGCAAGCTGTTGAACAGCAGATCCAGAGCCATAGAGAAACTCATCAAAAACAGATCAGTA
GTTTGAGAGATGAAGTAGAAGCAAAAGCAAAACTTATTACTGATCTTCAAGACCAAAACCAGAAAATGATGTTAGAGCAGGAACGTCTAA
GAGTAGAACATGAGAAGTTGAAAGCCACAGATCAGGAAAAGAGCAGAAAACTACATGAACTTACGGTTATGCAAGATAGACGAGAACAAG
CAAGACAAGACTTGAAGGGTTTGGAAGAGACAGTGGCAAAAGAACTTCAGACTTTACACAACCTGCGCAAACTCTTTGTTCAGGACCTGG
CTACAAGAGTTAAAAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAATTTGGAA
AAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCTCCCCGA
GTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCAGCCAGG
ATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTGGCTACC
TGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTGCCTGGC
AGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGGGGCGGA
AGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAGTTAAAT
GGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCGTGACCC
TAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACAACTGCA
GCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACCTGGAGA
AGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAGAGGAGG
AGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGCATGTCAGACC
CGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCAAATGATAGTGTATATG
CTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTCTTTGTGAAAGGTAATGGACTCACAAGGG
GAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCGAGCCGTGTTCAGTTCCCAGGTGGCAGAC
TCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTCCCTCCTAGCAGACATGCCACACCGGGTA
AGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGTTGGTCTGTGTCCATCAGTGACCACCAAC
ATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAACTGTTGGATTTTTCTAGTTGCCGCCAAAC
AAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCCCTGATGACCTGTCCTTATTCAGAATGAG
AGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGGCCCCGAGGATGGGCCTGGGCTCAGCATT
CGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTTTCATCATGATTAAGATGATTCCTAGATT
TAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGGCTCACAAGACACATTTGTCCCCCGGGCC
CACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGAAGAAAGGGGGCTGTTGGAGTCCCAGAAT
TGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCACAGCCAAGTAGAGGCGAAAGCAGTGGCT
CATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTACTCATAAAGGGACAGGCTAGCTAGCTGT
GTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGAAAAAGATGGTGTTTGGCTCTTATAGAGC
CTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATGTTTCTGTTTCTTAGATTCTGACCATGAC
TCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCAGTCTTGTGGGGGCAGCTTTTGGGAAGTC
TCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCAAAACACTGCCTGCTCTTCAGACTTAAAG
CACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAAACAGCAAAATTGTGGCATTTTGTGAGGC
CAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAGTTTGAAAAATGCTTATTGGACACGTAAC
CTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATAGACATGGTAAACTTTTGGTTTTCAGATA
TGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAATGCCTACACAGTAAGTGTGAATTGCTGCA
ACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAATTTATCCTTGACCAATTTATCCTTGACC
AATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAATTTTCATACACGTAAATGCAGAAGTTACT
AAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCTATTTATGAAAGGTCATTAAACCAGATCA

>42734_42734_4_KIF5B-RET_KIF5B_chr10_32307243_ENST00000302418_RET_chr10_43612030_ENST00000355710_length(amino acids)=1215AA_BP=813
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELA
ACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLR
DEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATR
VKKEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGACSQDGP
LLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAEGRKMK
ISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPDNCSEE
MYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNW

--------------------------------------------------------------
>42734_42734_5_KIF5B-RET_KIF5B_chr10_32311775_ENST00000302418_RET_chr10_43612031_ENST00000340058_length(transcript)=4205nt_BP=2372nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGCAGCCTGAGGGAACTGGCATGATAGATGAAGAGTTCACTGTTGCAAGACTCTACATTAGCAAAATGA
AGTCAGAAGTAAAAACCATGGTGAAACGTTGCAAGCAGTTAGAAAGCACACAAACTGAGAGCAACAAAAAAATGGAAGAAAATGAAAAGG
AGTTAGCAGCATGTCAGCTTCGTATCTCTCAAGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAG
AAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAG
AGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATG
GGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAG
TGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCA
TCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGG
TAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTC
GGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGT
GGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGA
GGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCA
GCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACG
GCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCT
ATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCTTTTTAAAAATGTT
TCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTTAGGCATTATTGCA
ACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAAACAGATCAGGGCG
GAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTTAACTAAGTGGATA
AATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCAGGTTCCCCCAGAC
CCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGTCCCAGCCACATGT
CCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCTTTCCCTTACCCAC
CTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTGCTGTGGTCTTACA

>42734_42734_5_KIF5B-RET_KIF5B_chr10_32311775_ENST00000302418_RET_chr10_43612031_ENST00000340058_length(amino acids)=998AA_BP=638
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELA
ACQLRISQEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGAC
SQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE
GRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPD
NCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGR

--------------------------------------------------------------
>42734_42734_6_KIF5B-RET_KIF5B_chr10_32311775_ENST00000302418_RET_chr10_43612031_ENST00000355710_length(transcript)=5663nt_BP=2372nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGCAGCCTGAGGGAACTGGCATGATAGATGAAGAGTTCACTGTTGCAAGACTCTACATTAGCAAAATGA
AGTCAGAAGTAAAAACCATGGTGAAACGTTGCAAGCAGTTAGAAAGCACACAAACTGAGAGCAACAAAAAAATGGAAGAAAATGAAAAGG
AGTTAGCAGCATGTCAGCTTCGTATCTCTCAAGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAG
AAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAG
AGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATG
GGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAG
TGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCA
TCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGG
TAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTC
GGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGT
GGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGA
GGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCA
GCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACG
GCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCT
ATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCAA
ATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTCTTTGTGAAAGGTA
ATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCGAGCCGTGTTCAGT
TCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTCCCTCCTAGCAGAC
ATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGTTGGTCTGTGTCCA
TCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAACTGTTGGATTTTTC
TAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCCCTGATGACCTGTC
CTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGGCCCCGAGGATGGG
CCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTTTCATCATGATTAA
GATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGGCTCACAAGACACA
TTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGAAGAAAGGGGGCTG
TTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCACAGCCAAGTAGAG
GCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTACTCATAAAGGGAC
AGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGAAAAAGATGGTGTT
TGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATGTTTCTGTTTCTTA
GATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCAGTCTTGTGGGGGC
AGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCAAAACACTGCCTGC
TCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAAACAGCAAAATTGT
GGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAGTTTGAAAAATGCT
TATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATAGACATGGTAAACT
TTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAATGCCTACACAGTAA
GTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAATTTATCCTTGACC
AATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAATTTTCATACACGTA
AATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCTATTTATGAAAGGT

>42734_42734_6_KIF5B-RET_KIF5B_chr10_32311775_ENST00000302418_RET_chr10_43612031_ENST00000355710_length(amino acids)=1040AA_BP=638
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELA
ACQLRISQEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGAC
SQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE
GRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPD
NCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGM

--------------------------------------------------------------
>42734_42734_7_KIF5B-RET_KIF5B_chr10_32311775_ENST00000302418_RET_chr10_43612032_ENST00000340058_length(transcript)=4205nt_BP=2372nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGCAGCCTGAGGGAACTGGCATGATAGATGAAGAGTTCACTGTTGCAAGACTCTACATTAGCAAAATGA
AGTCAGAAGTAAAAACCATGGTGAAACGTTGCAAGCAGTTAGAAAGCACACAAACTGAGAGCAACAAAAAAATGGAAGAAAATGAAAAGG
AGTTAGCAGCATGTCAGCTTCGTATCTCTCAAGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAG
AAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAG
AGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATG
GGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAG
TGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCA
TCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGG
TAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTC
GGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGT
GGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGA
GGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCA
GCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACG
GCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCT
ATGGTAGAATTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCTTTTTAAAAATGTT
TCTGGTCTGAACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTTAGGCATTATTGCA
ACTATGTTTTTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAAACAGATCAGGGCG
GAACTCTCAGGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTTAACTAAGTGGATA
AATATACAAATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCAGGTTCCCCCAGAC
CCCTCCTGGGCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGTCCCAGCCACATGT
CCTCCATCAGGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCTTTCCCTTACCCAC
CTTCAGGACGGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTGCTGTGGTCTTACA

>42734_42734_7_KIF5B-RET_KIF5B_chr10_32311775_ENST00000302418_RET_chr10_43612032_ENST00000340058_length(amino acids)=998AA_BP=638
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELA
ACQLRISQEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGAC
SQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE
GRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPD
NCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGR

--------------------------------------------------------------
>42734_42734_8_KIF5B-RET_KIF5B_chr10_32311775_ENST00000302418_RET_chr10_43612032_ENST00000355710_length(transcript)=5663nt_BP=2372nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGCAGCCTGAGGGAACTGGCATGATAGATGAAGAGTTCACTGTTGCAAGACTCTACATTAGCAAAATGA
AGTCAGAAGTAAAAACCATGGTGAAACGTTGCAAGCAGTTAGAAAGCACACAAACTGAGAGCAACAAAAAAATGGAAGAAAATGAAAAGG
AGTTAGCAGCATGTCAGCTTCGTATCTCTCAAGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAG
AAGGCGAATTTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAG
AGAACGCCTCCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATG
GGGCCTGCAGCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAG
TGGGGCCTGGCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCA
TCTCATTTGCCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGG
TAGCTGAGGGGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTC
GGATTCCAGTTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGT
GGGAGATCGTGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGA
GGCCAGACAACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCA
GCAAAGACCTGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACG
GCCTCTCAGAGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCT
ATGGCATGTCAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCAA
ATGATAGTGTATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTCTTTGTGAAAGGTA
ATGGACTCACAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCGAGCCGTGTTCAGT
TCCCAGGTGGCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTCCCTCCTAGCAGAC
ATGCCACACCGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGTTGGTCTGTGTCCA
TCAGTGACCACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAACTGTTGGATTTTTC
TAGTTGCCGCCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCCCTGATGACCTGTC
CTTATTCAGAATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGGCCCCGAGGATGGG
CCTGGGCTCAGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTTTCATCATGATTAA
GATGATTCCTAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGGCTCACAAGACACA
TTTGTCCCCCGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGAAGAAAGGGGGCTG
TTGGAGTCCCAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCACAGCCAAGTAGAG
GCGAAAGCAGTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTACTCATAAAGGGAC
AGGCTAGCTAGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGAAAAAGATGGTGTT
TGGCTCTTATAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATGTTTCTGTTTCTTA
GATTCTGACCATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCAGTCTTGTGGGGGC
AGCTTTTGGGAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCAAAACACTGCCTGC
TCTTCAGACTTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAAACAGCAAAATTGT
GGCATTTTGTGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAGTTTGAAAAATGCT
TATTGGACACGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATAGACATGGTAAACT
TTTGGTTTTCAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAATGCCTACACAGTAA
GTGTGAATTGCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAATTTATCCTTGACC
AATTTATCCTTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAATTTTCATACACGTA
AATGCAGAAGTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCTATTTATGAAAGGT

>42734_42734_8_KIF5B-RET_KIF5B_chr10_32311775_ENST00000302418_RET_chr10_43612032_ENST00000355710_length(amino acids)=1040AA_BP=638
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELA
ACQLRISQEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPSELRDLLSEFNVLKQVNHPHVIKLYGAC
SQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQISQGMQYLAEMKLVHRDLAARNILVAE
GRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGIPPERLFNLLKTGHRMERPD
NCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGM

--------------------------------------------------------------
>42734_42734_9_KIF5B-RET_KIF5B_chr10_32317355_ENST00000302418_RET_chr10_43612030_ENST00000340058_length(transcript)=4016nt_BP=2183nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAAT
TTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCT
CCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCA
GCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTG
GCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTG
CCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGG
GGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAG
TTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCG
TGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACA
ACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACC
TGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAG
AGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGTAGAA
TTTCCCATGCATTTACTAGATTCTAGCACCGCTGTCCCCTTTGCACTATCCTTCCTCTCTGTGATGCTTTTTAAAAATGTTTCTGGTCTG
AACAAAACCAAAGTCTGCTCTGAACCTTTTTATTTGTAAATGTCTGACTTTGCATCCAGTTTACATTTAGGCATTATTGCAACTATGTTT
TTCTAAAAGGATGTGAAAATAAGTGTAATTACCACATTGCCCAGCAACTTAGGATGGTAGAGGAAAAAACAGATCAGGGCGGAACTCTCA
GGGGAGACCAAGAACAGGTTGAATAAGGCGCTTCTGGGGTGGGAATCAAGTCATAGTACTTCTACTTTAACTAAGTGGATAAATATACAA
ATCTGGGGAGGTATTCAGTTGAGAAAGGAGCCACCAGCACCACTCAGCCTGCACTGGGAGCACAGCCAGGTTCCCCCAGACCCCTCCTGG
GCAGGCAGGTGCCTCTCAGAGGCCACCCGGCACTGGCGAGCAGCCACTGGCCAAGCCTCAGCCCCAGTCCCAGCCACATGTCCTCCATCA
GGGGTAGCGAGGTTGCAGGAGCTGGCTGGCCCTGGGAGGACGCACCCCCACTGCTGTTTTCACATCCTTTCCCTTACCCACCTTCAGGAC
GGTTGTCACTTATGAAGTCAGTGCTAAAGCTGGAGCAGTTGCTTTTTGAAAGAACATGGTCTGTGGTGCTGTGGTCTTACAATGGACAGT

>42734_42734_9_KIF5B-RET_KIF5B_chr10_32317355_ENST00000302418_RET_chr10_43612030_ENST00000340058_length(amino acids)=935AA_BP=575
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPS
ELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQ
ISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTL
GGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEE

--------------------------------------------------------------
>42734_42734_10_KIF5B-RET_KIF5B_chr10_32317355_ENST00000302418_RET_chr10_43612030_ENST00000355710_length(transcript)=5474nt_BP=2183nt
CGCCCTGTCGCCCAACGGCGGCCTCAGGAGTGATCGGGCAGCAGTCGGCCGGCCAGCGGACGGCAGAGCGGGCGGACGGGTAGGCCCGGC
CTGCTCTTCGCGAGGAGGAAGAAGGTGGCCACTCTCCCGGTCCCCAGAACCTCCCCAGCCCCCGCAGTCCGCCCAGACCGTAAAGGGGGA
CGCTGAGGAGCCGCGGACGCTCTCCCCGGTGCCGCCGCCGCTGCCGCCGCCATGGCTGCCATGATGGATCGGAAGTGAGCATTAGGGTTA
ACGGCTGCCGGCGCCGGCTCTTCAAGTCCCGGCTCCCCGGCCGCCTCCACCCGGGGAAGCGCAGCGCGGCGCAGCTGACTGCTGCCTCTC
ACGGCCCTCGCGACCACAAGCCCTCAGGTCCGGCGCGTTCCCTGCAAGACTGAGCGGCGGGGAGTGGCTCCCGGCCGCCGGCCCCGGCTG
CGAGAAAGATGGCGGACCTGGCCGAGTGCAACATCAAAGTGATGTGTCGCTTCAGACCTCTCAACGAGTCTGAAGTGAACCGCGGCGACA
AGTACATCGCCAAGTTTCAGGGAGAAGACACGGTCGTGATCGCGTCCAAGCCTTATGCATTTGATCGGGTGTTCCAGTCAAGCACATCTC
AAGAGCAAGTGTATAATGACTGTGCAAAGAAGATTGTTAAAGATGTACTTGAAGGATATAATGGAACAATATTTGCATATGGACAAACAT
CCTCTGGGAAGACACACACAATGGAGGGTAAACTTCATGATCCAGAAGGCATGGGAATTATTCCAAGAATAGTGCAAGATATTTTTAATT
ATATTTACTCCATGGATGAAAATTTGGAATTTCATATTAAGGTTTCATATTTTGAAATATATTTGGATAAGATAAGGGACCTGTTAGATG
TTTCAAAGACCAACCTTTCAGTTCATGAAGACAAAAACCGAGTTCCCTATGTAAAGGGGTGCACAGAGCGTTTTGTATGTAGTCCAGATG
AAGTTATGGATACCATAGATGAAGGAAAATCCAACAGACATGTAGCAGTTACAAATATGAATGAACATAGCTCTAGGAGTCACAGTATAT
TTCTTATTAATGTCAAACAAGAGAACACACAAACGGAACAAAAGCTGAGTGGAAAACTTTATCTGGTTGATTTAGCTGGTAGTGAAAAGG
TTAGTAAAACTGGAGCTGAAGGTGCTGTGCTGGATGAAGCTAAAAACATCAACAAGTCACTTTCTGCTCTTGGAAATGTTATTTCTGCTT
TGGCTGAGGGTAGTACATATGTTCCATATCGAGATAGTAAAATGACAAGAATCCTTCAAGATTCATTAGGTGGCAACTGTAGAACCACTA
TTGTAATTTGCTGCTCTCCATCATCATACAATGAGTCTGAAACAAAATCTACACTCTTATTTGGCCAAAGGGCCAAAACAATTAAGAACA
CAGTTTGTGTCAATGTGGAGTTAACTGCAGAACAGTGGAAAAAGAAGTATGAAAAAGAAAAAGAAAAAAATAAGATCCTGCGGAACACTA
TTCAGTGGCTTGAAAATGAGCTCAACAGATGGCGTAATGGGGAGACGGTGCCTATTGATGAACAGTTTGACAAAGAGAAAGCCAACTTGG
AAGCTTTCACAGTGGATAAAGATATTACTCTTACCAATGATAAACCAGCAACCGCAATTGGAGTTATAGGAAATTTTACTGATGCTGAAA
GAAGAAAGTGTGAAGAAGAAATTGCTAAATTATACAAACAGCTTGATGACAAGGATGAAGAAATTAACCAGCAAAGTCAACTGGTAGAGA
AACTGAAGACGCAAATGTTGGATCAGGAGGAGCTTTTGGCATCTACCAGAAGGGATCAAGACAATATGCAAGCTGAGCTGAATCGCCTTC
AAGCAGAAAATGATGCCTCTAAAGAAGAAGTGAAAGAAGTTTTACAGGCCCTAGAAGAACTTGCTGTCAATTATGATCAGAAGTCTCAGG
AAGTTGAAGACAAAACTAAGGAATATGAATTGCTTAGTGATGAATTGAATCAGAAATCGGCAACTTTAGCGAGTATAGATGCTGAGCTTC
AGAAACTTAAGGAAATGACCAACCACCAGAAAAAACGAGCAGCTGAGATGATGGCATCTTTACTAAAAGACCTTGCAGAAATAGGAATTG
CTGTGGGAAATAATGATGTAAAGGAGGATCCAAAGTGGGAATTCCCTCGGAAGAACTTGGTTCTTGGAAAAACTCTAGGAGAAGGCGAAT
TTGGAAAAGTGGTCAAGGCAACGGCCTTCCATCTGAAAGGCAGAGCAGGGTACACCACGGTGGCCGTGAAGATGCTGAAAGAGAACGCCT
CCCCGAGTGAGCTGCGAGACCTGCTGTCAGAGTTCAACGTCCTGAAGCAGGTCAACCACCCACATGTCATCAAATTGTATGGGGCCTGCA
GCCAGGATGGCCCGCTCCTCCTCATCGTGGAGTACGCCAAATACGGCTCCCTGCGGGGCTTCCTCCGCGAGAGCCGCAAAGTGGGGCCTG
GCTACCTGGGCAGTGGAGGCAGCCGCAACTCCAGCTCCCTGGACCACCCGGATGAGCGGGCCCTCACCATGGGCGACCTCATCTCATTTG
CCTGGCAGATCTCACAGGGGATGCAGTATCTGGCCGAGATGAAGCTCGTTCATCGGGACTTGGCAGCCAGAAACATCCTGGTAGCTGAGG
GGCGGAAGATGAAGATTTCGGATTTCGGCTTGTCCCGAGATGTTTATGAAGAGGATTCCTACGTGAAGAGGAGCCAGGGTCGGATTCCAG
TTAAATGGATGGCAATTGAATCCCTTTTTGATCATATCTACACCACGCAAAGTGATGTATGGTCTTTTGGTGTCCTGCTGTGGGAGATCG
TGACCCTAGGGGGAAACCCCTATCCTGGGATTCCTCCTGAGCGGCTCTTCAACCTTCTGAAGACCGGCCACCGGATGGAGAGGCCAGACA
ACTGCAGCGAGGAGATGTACCGCCTGATGCTGCAATGCTGGAAGCAGGAGCCGGACAAAAGGCCGGTGTTTGCGGACATCAGCAAAGACC
TGGAGAAGATGATGGTTAAGAGGAGAGACTACTTGGACCTTGCGGCGTCCACTCCATCTGACTCCCTGATTTATGACGACGGCCTCTCAG
AGGAGGAGACACCGCTGGTGGACTGTAATAATGCCCCCCTCCCTCGAGCCCTCCCTTCCACATGGATTGAAAACAAACTCTATGGCATGT
CAGACCCGAACTGGCCTGGAGAGAGTCCTGTACCACTCACGAGAGCTGATGGCACTAACACTGGGTTTCCAAGATATCCAAATGATAGTG
TATATGCTAACTGGATGCTTTCACCCTCAGCGGCAAAATTAATGGACACGTTTGATAGTTAACATTTCTTTGTGAAAGGTAATGGACTCA
CAAGGGGAAGAAACATGCTGAGAATGGAAAGTCTACCGGCCCTTTCTTTGTGAACGTCACATTGGCCGAGCCGTGTTCAGTTCCCAGGTG
GCAGACTCGTTTTTGGTAGTTTGTTTTAACTTCCAAGGTGGTTTTACTTCTGATAGCCGGTGATTTTCCCTCCTAGCAGACATGCCACAC
CGGGTAAGAGCTCTGAGTCTTAGTGGTTAAGCATTCCTTTCTCTTCAGTGCCCAGCAGCACCCAGTGTTGGTCTGTGTCCATCAGTGACC
ACCAACATTCTGTGTTCACATGTGTGGGTCCAACACTTACTACCTGGTGTATGAAATTGGACCTGAACTGTTGGATTTTTCTAGTTGCCG
CCAAACAAGGCAAAAAAATTTAAACATGAAGCACACACACAAAAAAGGCAGTAGGAAAAATGCTGGCCCTGATGACCTGTCCTTATTCAG
AATGAGAGACTGCGGGGGGGGCCTGGGGGTAGTGTCAATGCCCCTCCAGGGCTGGAGGGGAAGAGGGGCCCCGAGGATGGGCCTGGGCTC
AGCATTCGAGATCTTGAGAATGATTTTTTTTAAATCATGCAACCTTTCCTTAGGAAGACATTTGGTTTTCATCATGATTAAGATGATTCC
TAGATTTAGCACAATGGAGAGATTCCATGCCATCTTTACTATGTGGATGGTGGTATCAGGGAAGAGGGCTCACAAGACACATTTGTCCCC
CGGGCCCACCACATCATCCTCACGTGTTCGGTACTGAGCAGCCACTACCCCTGATGAGAACAGTATGAAGAAAGGGGGCTGTTGGAGTCC
CAGAATTGCTGACAGCAGAGGCTTTGCTGCTGTGAATCCCACCTGCCACCAGCCTGCAGCACACCCCACAGCCAAGTAGAGGCGAAAGCA
GTGGCTCATCCTACCTGTTAGGAGCAGGTAGGGCTTGTACTCACTTTAATTTGAATCTTATCAACTTACTCATAAAGGGACAGGCTAGCT
AGCTGTGTTAGAAGTAGCAATGACAATGACCAAGGACTGCTACACCTCTGATTACAATTCTGATGTGAAAAAGATGGTGTTTGGCTCTTA
TAGAGCCTGTGTGAAAGGCCCATGGATCAGCTCTTCCTGTGTTTGTAATTTAATGCTGCTACAAGATGTTTCTGTTTCTTAGATTCTGAC
CATGACTCATAAGCTTCTTGTCATTCTTCATTGCTTGTTTGTGGTCACAGATGCACAACACTCCTCCAGTCTTGTGGGGGCAGCTTTTGG
GAAGTCTCAGCAGCTCTTCTGGCTGTGTTGTCAGCACTGTAACTTCGCAGAAAAGAGTCGGATTACCAAAACACTGCCTGCTCTTCAGAC
TTAAAGCACTGATAGGACTTAAAATAGTCTCATTCAAATACTGTATTTTATATAGGCATTTCACAAAAACAGCAAAATTGTGGCATTTTG
TGAGGCCAAGGCTTGGATGCGTGTGTAATAGAGCCTTGTGGTGTGTGCGCACACACCCAGAGGGAGAGTTTGAAAAATGCTTATTGGACA
CGTAACCTGGCTCTAATTTGGGCTGTTTTTCAGATACACTGTGATAAGTTCTTTTACAAATATCTATAGACATGGTAAACTTTTGGTTTT
CAGATATGCTTAATGATAGTCTTACTAAATGCAGAAATAAGAATAAACTTTCTCAAATTATTAAAAATGCCTACACAGTAAGTGTGAATT
GCTGCAACAGGTTTGTTCTCAGGAGGGTAAGAACTCCAGGTCTAAACAGCTGACCCAGTGATGGGGAATTTATCCTTGACCAATTTATCC
TTGACCAATAACCTAATTGTCTATTCCTGAGTTATAAAAGTCCCCATCCTTATTAGCTCTACTGGAATTTTCATACACGTAAATGCAGAA
GTTACTAAGTATTAAGTATTACTGAGTATTAAGTAGTAATCTGTCAGTTATTAAAATTTGTAAAATCTATTTATGAAAGGTCATTAAACC

>42734_42734_10_KIF5B-RET_KIF5B_chr10_32317355_ENST00000302418_RET_chr10_43612030_ENST00000355710_length(amino acids)=977AA_BP=575
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSG
KTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE
GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLK
TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKEDPKWEFPRKNLVLGKTLGEGEFGKVVKATAFHLKGRAGYTTVAVKMLKENASPS
ELRDLLSEFNVLKQVNHPHVIKLYGACSQDGPLLLIVEYAKYGSLRGFLRESRKVGPGYLGSGGSRNSSSLDHPDERALTMGDLISFAWQ
ISQGMQYLAEMKLVHRDLAARNILVAEGRKMKISDFGLSRDVYEEDSYVKRSQGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTL
GGNPYPGIPPERLFNLLKTGHRMERPDNCSEEMYRLMLQCWKQEPDKRPVFADISKDLEKMMVKRRDYLDLAASTPSDSLIYDDGLSEEE

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Fusion Gene PPI Analysis for KIF5B-RET


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KIF5B-RET


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KIF5B-RET


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource