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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:KIRREL-HMMR (FusionGDB2 ID:42790)

Fusion Gene Summary for KIRREL-HMMR

Fusion gene summary

Fusion gene information	Fusion gene name: KIRREL-HMMR
	Fusion gene ID: 42790
		Hgene	Tgene
	Gene symbol	KIRREL	HMMR
	Gene ID	55243	3161
	Gene name	kirre like nephrin family adhesion molecule 1	hyaluronan mediated motility receptor
	Synonyms	KIRREL\|NEPH1	CD168\|IHABP\|RHAMM
	Cytomap	1q23.1	5q34
	Type of gene	protein-coding	protein-coding
	Description	kin of IRRE-like protein 1kin of IRRE likekin of irregular chiasm-like protein 1nephrin relatednephrin-like protein 1	hyaluronan mediated motility receptorintracellular hyaluronic acid-binding proteinreceptor for hyaluronan-mediated motility
	Modification date	20200313	20200313
	UniProtAcc	.	.
	Ensembl transtripts involved in fusion gene	ENST00000359209, ENST00000368173, ENST00000392272, ENST00000416935, ENST00000360089, ENST00000368172,	ENST00000358715, ENST00000432118, ENST00000353866, ENST00000393915,
Fusion gene scores	* DoF score	11 X 5 X 6=330	3 X 2 X 3=18
	# samples	13	3
	** MAII score	log2(13/330*10)=-1.34395440121736 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(3/18*10)=0.736965594166206 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: KIRREL [Title/Abstract] AND HMMR [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	KIRREL(157963518)-HMMR(162890862), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across KIRREL (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across HMMR (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	OV	TCGA-24-1850-01A	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+

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Fusion Gene ORF analysis for KIRREL-HMMR

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000359209	ENST00000358715	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5CDS-intron	ENST00000359209	ENST00000432118	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5CDS-intron	ENST00000368173	ENST00000358715	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5CDS-intron	ENST00000368173	ENST00000432118	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5CDS-intron	ENST00000392272	ENST00000358715	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5CDS-intron	ENST00000392272	ENST00000432118	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5CDS-intron	ENST00000416935	ENST00000358715	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5CDS-intron	ENST00000416935	ENST00000432118	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5UTR-3CDS	ENST00000360089	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5UTR-3CDS	ENST00000360089	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5UTR-intron	ENST00000360089	ENST00000358715	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
5UTR-intron	ENST00000360089	ENST00000432118	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
In-frame	ENST00000359209	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
In-frame	ENST00000359209	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
In-frame	ENST00000368173	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
In-frame	ENST00000368173	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
In-frame	ENST00000392272	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
In-frame	ENST00000392272	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
In-frame	ENST00000416935	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
In-frame	ENST00000416935	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
intron-3CDS	ENST00000368172	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
intron-3CDS	ENST00000368172	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
intron-intron	ENST00000368172	ENST00000358715	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+
intron-intron	ENST00000368172	ENST00000432118	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000392272	KIRREL	chr1	157963518	+	ENST00000353866	HMMR	chr5	162890862	+	2955	456	404	2539	711
ENST00000392272	KIRREL	chr1	157963518	+	ENST00000393915	HMMR	chr5	162890862	+	3365	456	404	2587	727
ENST00000368173	KIRREL	chr1	157963518	+	ENST00000353866	HMMR	chr5	162890862	+	2955	456	404	2539	711
ENST00000368173	KIRREL	chr1	157963518	+	ENST00000393915	HMMR	chr5	162890862	+	3365	456	404	2587	727
ENST00000359209	KIRREL	chr1	157963518	+	ENST00000353866	HMMR	chr5	162890862	+	2618	119	67	2202	711
ENST00000359209	KIRREL	chr1	157963518	+	ENST00000393915	HMMR	chr5	162890862	+	3028	119	67	2250	727
ENST00000416935	KIRREL	chr1	157963518	+	ENST00000353866	HMMR	chr5	162890862	+	2583	84	32	2167	711
ENST00000416935	KIRREL	chr1	157963518	+	ENST00000393915	HMMR	chr5	162890862	+	2993	84	32	2215	727

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000392272	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+	0.001316673	0.9986833
ENST00000392272	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+	0.000711154	0.9992888
ENST00000368173	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+	0.001316673	0.9986833
ENST00000368173	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+	0.000711154	0.9992888
ENST00000359209	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+	0.001772175	0.9982279
ENST00000359209	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+	0.000818734	0.9991812
ENST00000416935	ENST00000353866	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+	0.001784892	0.9982151
ENST00000416935	ENST00000393915	KIRREL	chr1	157963518	+	HMMR	chr5	162890862	+	0.000812929	0.99918705

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Fusion Genomic Features for KIRREL-HMMR

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	1-p	p (fusion gene breakpoint)
KIRREL	chr1	157963522	+	HMMR	chr5	162890861	+	2.00E-05	0.9999801
KIRREL	chr1	157963522	+	HMMR	chr5	162890861	+	2.00E-05	0.9999801

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KIRREL-HMMR

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:157963518/chr5:162890862)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
.	.
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

HMMR

chr1:157963518

chr5:162890862

ENST00000353866

635_645

710.0

Region

Hyaluronic acid-binding

Tgene

HMMR

chr1:157963518

chr5:162890862

ENST00000353866

657_666

710.0

Region

Hyaluronic acid-binding

Tgene

HMMR

chr1:157963518

chr5:162890862

ENST00000358715

635_645

725.0

Region

Hyaluronic acid-binding

Tgene

HMMR

chr1:157963518

chr5:162890862

ENST00000358715

657_666

725.0

Region

Hyaluronic acid-binding

Tgene

HMMR

chr1:157963518

chr5:162890862

ENST00000393915

635_645

726.0

Region

Hyaluronic acid-binding

Tgene

HMMR

chr1:157963518

chr5:162890862

ENST00000393915

657_666

726.0

Region

Hyaluronic acid-binding

Tgene

HMMR

chr1:157963518

chr5:162890862

ENST00000432118

635_645

639.0

Region

Hyaluronic acid-binding

Tgene

HMMR

chr1:157963518

chr5:162890862

ENST00000432118

657_666

639.0

Region

Hyaluronic acid-binding

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000359209

120_216

758.0

Domain

Note=Ig-like C2-type 2

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000359209

21_115

758.0

Domain

Note=Ig-like C2-type 1

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000359209

223_299

758.0

Domain

Note=Ig-like C2-type 3

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000359209

308_387

758.0

Domain

Note=Ig-like C2-type 4

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000359209

392_488

758.0

Domain

Note=Ig-like C2-type 5

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000368173

120_216

774.0

Domain

Note=Ig-like C2-type 2

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000368173

21_115

774.0

Domain

Note=Ig-like C2-type 1

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000368173

223_299

774.0

Domain

Note=Ig-like C2-type 3

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000368173

308_387

774.0

Domain

Note=Ig-like C2-type 4

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000368173

392_488

774.0

Domain

Note=Ig-like C2-type 5

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000392272

120_216

655.0

Domain

Note=Ig-like C2-type 2

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000392272

21_115

655.0

Domain

Note=Ig-like C2-type 1

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000392272

223_299

655.0

Domain

Note=Ig-like C2-type 3

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000392272

308_387

655.0

Domain

Note=Ig-like C2-type 4

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000392272

392_488

655.0

Domain

Note=Ig-like C2-type 5

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000359209

405_407

758.0

Motif

Cell attachment site

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000368173

405_407

774.0

Motif

Cell attachment site

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000392272

405_407

655.0

Motif

Cell attachment site

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000359209

17_499

758.0

Topological domain

Extracellular

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000359209

521_757

758.0

Topological domain

Cytoplasmic

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000368173

17_499

774.0

Topological domain

Extracellular

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000368173

521_757

774.0

Topological domain

Cytoplasmic

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000392272

17_499

655.0

Topological domain

Extracellular

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000392272

521_757

655.0

Topological domain

Cytoplasmic

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000359209

500_520

758.0

Transmembrane

Helical

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000368173

500_520

774.0

Transmembrane

Helical

Hgene

KIRREL

chr1:157963518

chr5:162890862

ENST00000392272

500_520

655.0

Transmembrane

Helical

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Fusion Gene Sequence for KIRREL-HMMR

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>42790_42790_1_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000359209_HMMR_chr5_162890862_ENST00000353866_length(transcript)=2618nt_BP=119nt
CCGCTCCTCTGGCTCGCTCGCCAACTCCGGGCCCCAGCCGCGGGCGGGCGCACGGCGGGCGGACAGCATGCTGAGCCTCCTCGTCTGGAT
CCTCACTCTCTCCGATACTTTCTCCCAAGGTTGTGCACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGT
ATCCTTTCAGAAATCACAAAGATTTAAACAGCAAAAAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGC
TAGAAAAGTTAAGTCTTCGGAATCAAAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACAGGCGGATCCAGGATCTGGAAACTGA
GTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGAAAAAACATCTCTCTCTGCAAATAATGCTACACTGGAAAAACAACTTAT
TGAATTGACCAGGACTAATGAACTACTAAAATCTAAGTTTTCTGAAAATGGTAACCAGAAGAATTTGAGAATTCTAAGCTTGGAGTTGAT
GAAACTTAGAAACAAAAGAGAAACAAAGATGAGGGGTATGATGGCTAAGCAAGAAGGCATGGAGATGAAGCTGCAGGTCACCCAAAGGAG
TCTCGAAGAGTCTCAAGGGAAAATAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGATGAAAAATCTGAAACAGA
AAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGATCAAGTGGAAAAATACAAGCTAGATATTGCCCAGTTAGAAGAAAATTT
GAAAGAGAAGAATGATGAAATTTTAAGCCTTAAGCAGTCTCTTGAGGAGAATATTGTTATATTATCTAAACAAGTAGAAGATCTAAATGT
GAAATGTCAGCTGCTTGAAAAAGAAAAAGAAGACCATGTCAACAGGAATAGAGAACACAACGAAAATCTAAATGCAGAGATGCAAAACTT
AAAACAGAAGTTTATTCTTGAACAACAGGAACGTGAAAAGCTTCAACAAAAAGAATTACAAATTGATTCACTTCTGCAACAAGAGAAAGA
ATTATCTTCGAGTCTTCATCAGAAGCTCTGTTCTTTTCAAGAGGAAATGGTTAAAGAGAAGAATCTGTTTGAGGAAGAATTAAAGCAAAC
ACTGGATGAGCTTGATAAATTACAGCAAAAGGAGGAACAAGCTGAAAGGCTGGTCAAGCAATTGGAAGAGGAAGCAAAATCTAGAGCTGA
AGAATTAAAACTCCTAGAAGAAAAGCTGAAAGGGAAGGAGGCTGAACTGGAGAAAAGTAGTGCTGCTCATACCCAGGCCACCCTGCTTTT
GCAGGAAAAGTATGACAGTATGGTGCAAAGCCTTGAAGATGTTACTGCTCAATTTGAAAGCTATAAAGCGTTAACAGCCAGTGAGATAGA
AGATCTTAAGCTGGAGAACTCATCATTACAGGAAAAAGCGGCCAAGGCTGGGAAAAATGCAGAGGATGTTCAGCATCAGATTTTGGCAAC
TGAGAGCTCAAATCAAGAATATGTAAGGATGCTTCTAGATCTGCAGACCAAGTCAGCACTAAAGGAAACAGAAATTAAAGAAATCACAGT
TTCTTTTCTTCAAAAAATAACTGATTTGCAGAACCAACTCAAGCAACAGGAGGAAGACTTTAGAAAACAGCTGGAAGATGAAGAAGGAAG
AAAAGCTGAAAAAGAAAATACAACAGCAGAATTAACTGAAGAAATTAACAAGTGGCGTCTCCTCTATGAAGAACTATATAATAAAACAAA
ACCTTTTCAGCTACAACTAGATGCTTTTGAAGTAGAAAAACAGGCATTGTTGAATGAACATGGTGCAGCTCAGGAACAGCTAAATAAAAT
AAGAGATTCATATGCTAAATTATTGGGTCATCAGAATTTGAAACAAAAAATCAAGCATGTTGTGAAGTTGAAAGATGAAAATAGCCAACT
CAAATCGGAAGTATCAAAACTCCGCTGTCAGCTTGCTAAAAAAAAACAAAGTGAGACAAAACTTCAAGAGGAATTGAATAAAGTTCTAGG
TATCAAACACTTTGATCCTTCAAAGGCTTTTCATCATGAAAGTAAAGAAAATTTTGCCCTGAAGACCCCATTAAAAGAAGGCAATACAAA
CTGTTACCGAGCTCCTATGGAGTGTCAAGAATCATGGAAGTAAACATCTGAGAAACCTGTTGAAGATTATTTCATTCGTCTTGTTGTTAT
TGATGTTGCTGTTATTATATTTGACATGGGTATTTTATAATGTTGTATTTAATTTTAACTGCCAATCCTTAAATATGTGAAAGGAACATT
TTTTACCAAAGTGTCTTTTGACATTTTATTTTTTCTTGCAAATACCTCCTCCCTAATGCTCACCTTTATCACCTCATTCTGAACCCTTTC
GCTGGCTTTCCAGCTTAGAATGCATCTCATCAACTTAAAAGTCAGTATCATATTATTATCCTCCTGTTCTGAAACCTTAGTTTCAAGAGT
CTAAACCCCAGATTCTTCAGCTTGATCCTGGAGGTCTTTTCTAGTCTGAGCTTCTTTAGCTAGGCTAAAACACCTTGGCTTGTTATTGCC

>42790_42790_1_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000359209_HMMR_chr5_162890862_ENST00000353866_length(amino acids)=711AA_BP=17
MLSLLVWILTLSDTFSQGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKIRVLLQERGAQDR
RIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEM
KLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILS
KQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNL
FEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYK
ALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRK
QLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVK

--------------------------------------------------------------
>42790_42790_2_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000359209_HMMR_chr5_162890862_ENST00000393915_length(transcript)=3028nt_BP=119nt
CCGCTCCTCTGGCTCGCTCGCCAACTCCGGGCCCCAGCCGCGGGCGGGCGCACGGCGGGCGGACAGCATGCTGAGCCTCCTCGTCTGGAT
CCTCACTCTCTCCGATACTTTCTCCCAAGGTTGTGCACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGT
ATCCTTTCAGAAATCACAAAGATTTAAACAGCAAAAAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGC
TAGAAAAGTTAAGTCTTCGGAATCAAAGAAGGAATCTCAAAAGAATGATAAAGATTTGAAGATATTAGAGAAAGAGATTCGTGTTCTTCT
ACAGGAACGTGGTGCCCAGGACAGGCGGATCCAGGATCTGGAAACTGAGTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGA
AAAAACATCTCTCTCTGCAAATAATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGACTAATGAACTACTAAAATCTAAGTTTTC
TGAAAATGGTAACCAGAAGAATTTGAGAATTCTAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAACAAAGATGAGGGGTATGAT
GGCTAAGCAAGAAGGCATGGAGATGAAGCTGCAGGTCACCCAAAGGAGTCTCGAAGAGTCTCAAGGGAAAATAGCCCAACTGGAGGGAAA
ACTTGTTTCAATAGAGAAAGAAAAGATTGATGAAAAATCTGAAACAGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGA
TCAAGTGGAAAAATACAAGCTAGATATTGCCCAGTTAGAAGAAAATTTGAAAGAGAAGAATGATGAAATTTTAAGCCTTAAGCAGTCTCT
TGAGGAGAATATTGTTATATTATCTAAACAAGTAGAAGATCTAAATGTGAAATGTCAGCTGCTTGAAAAAGAAAAAGAAGACCATGTCAA
CAGGAATAGAGAACACAACGAAAATCTAAATGCAGAGATGCAAAACTTAAAACAGAAGTTTATTCTTGAACAACAGGAACGTGAAAAGCT
TCAACAAAAAGAATTACAAATTGATTCACTTCTGCAACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGAAGCTCTGTTCTTTTCAAGA
GGAAATGGTTAAAGAGAAGAATCTGTTTGAGGAAGAATTAAAGCAAACACTGGATGAGCTTGATAAATTACAGCAAAAGGAGGAACAAGC
TGAAAGGCTGGTCAAGCAATTGGAAGAGGAAGCAAAATCTAGAGCTGAAGAATTAAAACTCCTAGAAGAAAAGCTGAAAGGGAAGGAGGC
TGAACTGGAGAAAAGTAGTGCTGCTCATACCCAGGCCACCCTGCTTTTGCAGGAAAAGTATGACAGTATGGTGCAAAGCCTTGAAGATGT
TACTGCTCAATTTGAAAGCTATAAAGCGTTAACAGCCAGTGAGATAGAAGATCTTAAGCTGGAGAACTCATCATTACAGGAAAAAGCGGC
CAAGGCTGGGAAAAATGCAGAGGATGTTCAGCATCAGATTTTGGCAACTGAGAGCTCAAATCAAGAATATGTAAGGATGCTTCTAGATCT
GCAGACCAAGTCAGCACTAAAGGAAACAGAAATTAAAGAAATCACAGTTTCTTTTCTTCAAAAAATAACTGATTTGCAGAACCAACTCAA
GCAACAGGAGGAAGACTTTAGAAAACAGCTGGAAGATGAAGAAGGAAGAAAAGCTGAAAAAGAAAATACAACAGCAGAATTAACTGAAGA
AATTAACAAGTGGCGTCTCCTCTATGAAGAACTATATAATAAAACAAAACCTTTTCAGCTACAACTAGATGCTTTTGAAGTAGAAAAACA
GGCATTGTTGAATGAACATGGTGCAGCTCAGGAACAGCTAAATAAAATAAGAGATTCATATGCTAAATTATTGGGTCATCAGAATTTGAA
ACAAAAAATCAAGCATGTTGTGAAGTTGAAAGATGAAAATAGCCAACTCAAATCGGAAGTATCAAAACTCCGCTGTCAGCTTGCTAAAAA
AAAACAAAGTGAGACAAAACTTCAAGAGGAATTGAATAAAGTTCTAGGTATCAAACACTTTGATCCTTCAAAGGCTTTTCATCATGAAAG
TAAAGAAAATTTTGCCCTGAAGACCCCATTAAAAGAAGGCAATACAAACTGTTACCGAGCTCCTATGGAGTGTCAAGAATCATGGAAGTA
AACATCTGAGAAACCTGTTGAAGATTATTTCATTCGTCTTGTTGTTATTGATGTTGCTGTTATTATATTTGACATGGGTATTTTATAATG
TTGTATTTAATTTTAACTGCCAATCCTTAAATATGTGAAAGGAACATTTTTTACCAAAGTGTCTTTTGACATTTTATTTTTTCTTGCAAA
TACCTCCTCCCTAATGCTCACCTTTATCACCTCATTCTGAACCCTTTCGCTGGCTTTCCAGCTTAGAATGCATCTCATCAACTTAAAAGT
CAGTATCATATTATTATCCTCCTGTTCTGAAACCTTAGTTTCAAGAGTCTAAACCCCAGATTCTTCAGCTTGATCCTGGAGGTCTTTTCT
AGTCTGAGCTTCTTTAGCTAGGCTAAAACACCTTGGCTTGTTATTGCCTCTACTTTGATTCTGATAATGCTCACTTGGTCCTACCTATTA
TCCTTCTACTTGTCCAGTTCAAATAAGAAATAAGGACAAGCCTAACTTCATAGAAACCTCTCTATTTTTAATCAGTTGTTTAATAATTTA
CAGGTTCTTAGGCTCCATCCTGTTTGTATGAAATTATAATCTGTGGATTGGCCTTTAAGCCTGCATTCTTAACAAACTCTTCAGTTAATT
CTTAGATACACTAAAAATCTGAGAAACTCTACATGTAACTATTTCTTCAGAGTTTGTCATATACTGCTTGTCATCTGCATGTCTACTCAG

>42790_42790_2_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000359209_HMMR_chr5_162890862_ENST00000393915_length(amino acids)=727AA_BP=17
MLSLLVWILTLSDTFSQGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKKESQKNDKDLKIL
EKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKR
ETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDE
ILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLH
QKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDS
MVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI
TDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAK
LLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPM

--------------------------------------------------------------
>42790_42790_3_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000368173_HMMR_chr5_162890862_ENST00000353866_length(transcript)=2955nt_BP=456nt
GGCGCCGTCGGAGGGAGAGTAGACGTCAGGCGGAGGGAGGGAGGCAGGCAGGCAGGGAGGCAGGGAGGGAGAGAGGGAAGGAAGAGAAGG
GGAGAGAAAGGGGGAGCAAAGACCGAAAGAGACCCAGAGAGATACAGCTTGAGAGGAGAAATAATTAAAGGGGGAGGGCGACCAGGAGGA
GAAAAAGGTCTGGGAGGAAAGAGAGATAAAGAGAATCGGAGGGCAGGGAAATGAGTTTGTGCGCGTGAGTGTGCGCGCGCGCGTGTGTGT
GTGCAGGGGCGGGCGCGGGCGGGCGGGGGGCGGGCTCCCGGGCTCCCGGGCTCCCCTCCTCCCCAGCCCGCTCCTCTGGCTCGCTCGCCA
ACTCCGGGCCCCAGCCGCGGGCGGGCGCACGGCGGGCGGACAGCATGCTGAGCCTCCTCGTCTGGATCCTCACTCTCTCCGATACTTTCT
CCCAAGGTTGTGCACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGAT
TTAAACAGCAAAAAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAGTCTTCGGAAT
CAAAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACAGGCGGATCCAGGATCTGGAAACTGAGTTGGAAAAGATGGAAGCAAGGC
TAAATGCTGCACTAAGGGAAAAAACATCTCTCTCTGCAAATAATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGACTAATGAAC
TACTAAAATCTAAGTTTTCTGAAAATGGTAACCAGAAGAATTTGAGAATTCTAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAA
CAAAGATGAGGGGTATGATGGCTAAGCAAGAAGGCATGGAGATGAAGCTGCAGGTCACCCAAAGGAGTCTCGAAGAGTCTCAAGGGAAAA
TAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGATGAAAAATCTGAAACAGAAAAACTCTTGGAATACATCGAAG
AAATTAGTTGTGCTTCAGATCAAGTGGAAAAATACAAGCTAGATATTGCCCAGTTAGAAGAAAATTTGAAAGAGAAGAATGATGAAATTT
TAAGCCTTAAGCAGTCTCTTGAGGAGAATATTGTTATATTATCTAAACAAGTAGAAGATCTAAATGTGAAATGTCAGCTGCTTGAAAAAG
AAAAAGAAGACCATGTCAACAGGAATAGAGAACACAACGAAAATCTAAATGCAGAGATGCAAAACTTAAAACAGAAGTTTATTCTTGAAC
AACAGGAACGTGAAAAGCTTCAACAAAAAGAATTACAAATTGATTCACTTCTGCAACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGA
AGCTCTGTTCTTTTCAAGAGGAAATGGTTAAAGAGAAGAATCTGTTTGAGGAAGAATTAAAGCAAACACTGGATGAGCTTGATAAATTAC
AGCAAAAGGAGGAACAAGCTGAAAGGCTGGTCAAGCAATTGGAAGAGGAAGCAAAATCTAGAGCTGAAGAATTAAAACTCCTAGAAGAAA
AGCTGAAAGGGAAGGAGGCTGAACTGGAGAAAAGTAGTGCTGCTCATACCCAGGCCACCCTGCTTTTGCAGGAAAAGTATGACAGTATGG
TGCAAAGCCTTGAAGATGTTACTGCTCAATTTGAAAGCTATAAAGCGTTAACAGCCAGTGAGATAGAAGATCTTAAGCTGGAGAACTCAT
CATTACAGGAAAAAGCGGCCAAGGCTGGGAAAAATGCAGAGGATGTTCAGCATCAGATTTTGGCAACTGAGAGCTCAAATCAAGAATATG
TAAGGATGCTTCTAGATCTGCAGACCAAGTCAGCACTAAAGGAAACAGAAATTAAAGAAATCACAGTTTCTTTTCTTCAAAAAATAACTG
ATTTGCAGAACCAACTCAAGCAACAGGAGGAAGACTTTAGAAAACAGCTGGAAGATGAAGAAGGAAGAAAAGCTGAAAAAGAAAATACAA
CAGCAGAATTAACTGAAGAAATTAACAAGTGGCGTCTCCTCTATGAAGAACTATATAATAAAACAAAACCTTTTCAGCTACAACTAGATG
CTTTTGAAGTAGAAAAACAGGCATTGTTGAATGAACATGGTGCAGCTCAGGAACAGCTAAATAAAATAAGAGATTCATATGCTAAATTAT
TGGGTCATCAGAATTTGAAACAAAAAATCAAGCATGTTGTGAAGTTGAAAGATGAAAATAGCCAACTCAAATCGGAAGTATCAAAACTCC
GCTGTCAGCTTGCTAAAAAAAAACAAAGTGAGACAAAACTTCAAGAGGAATTGAATAAAGTTCTAGGTATCAAACACTTTGATCCTTCAA
AGGCTTTTCATCATGAAAGTAAAGAAAATTTTGCCCTGAAGACCCCATTAAAAGAAGGCAATACAAACTGTTACCGAGCTCCTATGGAGT
GTCAAGAATCATGGAAGTAAACATCTGAGAAACCTGTTGAAGATTATTTCATTCGTCTTGTTGTTATTGATGTTGCTGTTATTATATTTG
ACATGGGTATTTTATAATGTTGTATTTAATTTTAACTGCCAATCCTTAAATATGTGAAAGGAACATTTTTTACCAAAGTGTCTTTTGACA
TTTTATTTTTTCTTGCAAATACCTCCTCCCTAATGCTCACCTTTATCACCTCATTCTGAACCCTTTCGCTGGCTTTCCAGCTTAGAATGC
ATCTCATCAACTTAAAAGTCAGTATCATATTATTATCCTCCTGTTCTGAAACCTTAGTTTCAAGAGTCTAAACCCCAGATTCTTCAGCTT

>42790_42790_3_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000368173_HMMR_chr5_162890862_ENST00000353866_length(amino acids)=711AA_BP=17
MLSLLVWILTLSDTFSQGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKIRVLLQERGAQDR
RIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEM
KLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILS
KQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNL
FEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYK
ALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRK
QLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVK

--------------------------------------------------------------
>42790_42790_4_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000368173_HMMR_chr5_162890862_ENST00000393915_length(transcript)=3365nt_BP=456nt
GGCGCCGTCGGAGGGAGAGTAGACGTCAGGCGGAGGGAGGGAGGCAGGCAGGCAGGGAGGCAGGGAGGGAGAGAGGGAAGGAAGAGAAGG
GGAGAGAAAGGGGGAGCAAAGACCGAAAGAGACCCAGAGAGATACAGCTTGAGAGGAGAAATAATTAAAGGGGGAGGGCGACCAGGAGGA
GAAAAAGGTCTGGGAGGAAAGAGAGATAAAGAGAATCGGAGGGCAGGGAAATGAGTTTGTGCGCGTGAGTGTGCGCGCGCGCGTGTGTGT
GTGCAGGGGCGGGCGCGGGCGGGCGGGGGGCGGGCTCCCGGGCTCCCGGGCTCCCCTCCTCCCCAGCCCGCTCCTCTGGCTCGCTCGCCA
ACTCCGGGCCCCAGCCGCGGGCGGGCGCACGGCGGGCGGACAGCATGCTGAGCCTCCTCGTCTGGATCCTCACTCTCTCCGATACTTTCT
CCCAAGGTTGTGCACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGAT
TTAAACAGCAAAAAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAGTCTTCGGAAT
CAAAGAAGGAATCTCAAAAGAATGATAAAGATTTGAAGATATTAGAGAAAGAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACA
GGCGGATCCAGGATCTGGAAACTGAGTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGAAAAAACATCTCTCTCTGCAAATA
ATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGACTAATGAACTACTAAAATCTAAGTTTTCTGAAAATGGTAACCAGAAGAATT
TGAGAATTCTAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAACAAAGATGAGGGGTATGATGGCTAAGCAAGAAGGCATGGAGA
TGAAGCTGCAGGTCACCCAAAGGAGTCTCGAAGAGTCTCAAGGGAAAATAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAA
AGATTGATGAAAAATCTGAAACAGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGATCAAGTGGAAAAATACAAGCTAG
ATATTGCCCAGTTAGAAGAAAATTTGAAAGAGAAGAATGATGAAATTTTAAGCCTTAAGCAGTCTCTTGAGGAGAATATTGTTATATTAT
CTAAACAAGTAGAAGATCTAAATGTGAAATGTCAGCTGCTTGAAAAAGAAAAAGAAGACCATGTCAACAGGAATAGAGAACACAACGAAA
ATCTAAATGCAGAGATGCAAAACTTAAAACAGAAGTTTATTCTTGAACAACAGGAACGTGAAAAGCTTCAACAAAAAGAATTACAAATTG
ATTCACTTCTGCAACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGAAGCTCTGTTCTTTTCAAGAGGAAATGGTTAAAGAGAAGAATC
TGTTTGAGGAAGAATTAAAGCAAACACTGGATGAGCTTGATAAATTACAGCAAAAGGAGGAACAAGCTGAAAGGCTGGTCAAGCAATTGG
AAGAGGAAGCAAAATCTAGAGCTGAAGAATTAAAACTCCTAGAAGAAAAGCTGAAAGGGAAGGAGGCTGAACTGGAGAAAAGTAGTGCTG
CTCATACCCAGGCCACCCTGCTTTTGCAGGAAAAGTATGACAGTATGGTGCAAAGCCTTGAAGATGTTACTGCTCAATTTGAAAGCTATA
AAGCGTTAACAGCCAGTGAGATAGAAGATCTTAAGCTGGAGAACTCATCATTACAGGAAAAAGCGGCCAAGGCTGGGAAAAATGCAGAGG
ATGTTCAGCATCAGATTTTGGCAACTGAGAGCTCAAATCAAGAATATGTAAGGATGCTTCTAGATCTGCAGACCAAGTCAGCACTAAAGG
AAACAGAAATTAAAGAAATCACAGTTTCTTTTCTTCAAAAAATAACTGATTTGCAGAACCAACTCAAGCAACAGGAGGAAGACTTTAGAA
AACAGCTGGAAGATGAAGAAGGAAGAAAAGCTGAAAAAGAAAATACAACAGCAGAATTAACTGAAGAAATTAACAAGTGGCGTCTCCTCT
ATGAAGAACTATATAATAAAACAAAACCTTTTCAGCTACAACTAGATGCTTTTGAAGTAGAAAAACAGGCATTGTTGAATGAACATGGTG
CAGCTCAGGAACAGCTAAATAAAATAAGAGATTCATATGCTAAATTATTGGGTCATCAGAATTTGAAACAAAAAATCAAGCATGTTGTGA
AGTTGAAAGATGAAAATAGCCAACTCAAATCGGAAGTATCAAAACTCCGCTGTCAGCTTGCTAAAAAAAAACAAAGTGAGACAAAACTTC
AAGAGGAATTGAATAAAGTTCTAGGTATCAAACACTTTGATCCTTCAAAGGCTTTTCATCATGAAAGTAAAGAAAATTTTGCCCTGAAGA
CCCCATTAAAAGAAGGCAATACAAACTGTTACCGAGCTCCTATGGAGTGTCAAGAATCATGGAAGTAAACATCTGAGAAACCTGTTGAAG
ATTATTTCATTCGTCTTGTTGTTATTGATGTTGCTGTTATTATATTTGACATGGGTATTTTATAATGTTGTATTTAATTTTAACTGCCAA
TCCTTAAATATGTGAAAGGAACATTTTTTACCAAAGTGTCTTTTGACATTTTATTTTTTCTTGCAAATACCTCCTCCCTAATGCTCACCT
TTATCACCTCATTCTGAACCCTTTCGCTGGCTTTCCAGCTTAGAATGCATCTCATCAACTTAAAAGTCAGTATCATATTATTATCCTCCT
GTTCTGAAACCTTAGTTTCAAGAGTCTAAACCCCAGATTCTTCAGCTTGATCCTGGAGGTCTTTTCTAGTCTGAGCTTCTTTAGCTAGGC
TAAAACACCTTGGCTTGTTATTGCCTCTACTTTGATTCTGATAATGCTCACTTGGTCCTACCTATTATCCTTCTACTTGTCCAGTTCAAA
TAAGAAATAAGGACAAGCCTAACTTCATAGAAACCTCTCTATTTTTAATCAGTTGTTTAATAATTTACAGGTTCTTAGGCTCCATCCTGT
TTGTATGAAATTATAATCTGTGGATTGGCCTTTAAGCCTGCATTCTTAACAAACTCTTCAGTTAATTCTTAGATACACTAAAAATCTGAG
AAACTCTACATGTAACTATTTCTTCAGAGTTTGTCATATACTGCTTGTCATCTGCATGTCTACTCAGCATTTGATTAACATTTGTGTAAT

>42790_42790_4_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000368173_HMMR_chr5_162890862_ENST00000393915_length(amino acids)=727AA_BP=17
MLSLLVWILTLSDTFSQGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKKESQKNDKDLKIL
EKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKR
ETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDE
ILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLH
QKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDS
MVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI
TDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAK
LLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPM

--------------------------------------------------------------
>42790_42790_5_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000392272_HMMR_chr5_162890862_ENST00000353866_length(transcript)=2955nt_BP=456nt
GGCGCCGTCGGAGGGAGAGTAGACGTCAGGCGGAGGGAGGGAGGCAGGCAGGCAGGGAGGCAGGGAGGGAGAGAGGGAAGGAAGAGAAGG
GGAGAGAAAGGGGGAGCAAAGACCGAAAGAGACCCAGAGAGATACAGCTTGAGAGGAGAAATAATTAAAGGGGGAGGGCGACCAGGAGGA
GAAAAAGGTCTGGGAGGAAAGAGAGATAAAGAGAATCGGAGGGCAGGGAAATGAGTTTGTGCGCGTGAGTGTGCGCGCGCGCGTGTGTGT
GTGCAGGGGCGGGCGCGGGCGGGCGGGGGGCGGGCTCCCGGGCTCCCGGGCTCCCCTCCTCCCCAGCCCGCTCCTCTGGCTCGCTCGCCA
ACTCCGGGCCCCAGCCGCGGGCGGGCGCACGGCGGGCGGACAGCATGCTGAGCCTCCTCGTCTGGATCCTCACTCTCTCCGATACTTTCT
CCCAAGGTTGTGCACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGAT
TTAAACAGCAAAAAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAGTCTTCGGAAT
CAAAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACAGGCGGATCCAGGATCTGGAAACTGAGTTGGAAAAGATGGAAGCAAGGC
TAAATGCTGCACTAAGGGAAAAAACATCTCTCTCTGCAAATAATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGACTAATGAAC
TACTAAAATCTAAGTTTTCTGAAAATGGTAACCAGAAGAATTTGAGAATTCTAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAA
CAAAGATGAGGGGTATGATGGCTAAGCAAGAAGGCATGGAGATGAAGCTGCAGGTCACCCAAAGGAGTCTCGAAGAGTCTCAAGGGAAAA
TAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGATGAAAAATCTGAAACAGAAAAACTCTTGGAATACATCGAAG
AAATTAGTTGTGCTTCAGATCAAGTGGAAAAATACAAGCTAGATATTGCCCAGTTAGAAGAAAATTTGAAAGAGAAGAATGATGAAATTT
TAAGCCTTAAGCAGTCTCTTGAGGAGAATATTGTTATATTATCTAAACAAGTAGAAGATCTAAATGTGAAATGTCAGCTGCTTGAAAAAG
AAAAAGAAGACCATGTCAACAGGAATAGAGAACACAACGAAAATCTAAATGCAGAGATGCAAAACTTAAAACAGAAGTTTATTCTTGAAC
AACAGGAACGTGAAAAGCTTCAACAAAAAGAATTACAAATTGATTCACTTCTGCAACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGA
AGCTCTGTTCTTTTCAAGAGGAAATGGTTAAAGAGAAGAATCTGTTTGAGGAAGAATTAAAGCAAACACTGGATGAGCTTGATAAATTAC
AGCAAAAGGAGGAACAAGCTGAAAGGCTGGTCAAGCAATTGGAAGAGGAAGCAAAATCTAGAGCTGAAGAATTAAAACTCCTAGAAGAAA
AGCTGAAAGGGAAGGAGGCTGAACTGGAGAAAAGTAGTGCTGCTCATACCCAGGCCACCCTGCTTTTGCAGGAAAAGTATGACAGTATGG
TGCAAAGCCTTGAAGATGTTACTGCTCAATTTGAAAGCTATAAAGCGTTAACAGCCAGTGAGATAGAAGATCTTAAGCTGGAGAACTCAT
CATTACAGGAAAAAGCGGCCAAGGCTGGGAAAAATGCAGAGGATGTTCAGCATCAGATTTTGGCAACTGAGAGCTCAAATCAAGAATATG
TAAGGATGCTTCTAGATCTGCAGACCAAGTCAGCACTAAAGGAAACAGAAATTAAAGAAATCACAGTTTCTTTTCTTCAAAAAATAACTG
ATTTGCAGAACCAACTCAAGCAACAGGAGGAAGACTTTAGAAAACAGCTGGAAGATGAAGAAGGAAGAAAAGCTGAAAAAGAAAATACAA
CAGCAGAATTAACTGAAGAAATTAACAAGTGGCGTCTCCTCTATGAAGAACTATATAATAAAACAAAACCTTTTCAGCTACAACTAGATG
CTTTTGAAGTAGAAAAACAGGCATTGTTGAATGAACATGGTGCAGCTCAGGAACAGCTAAATAAAATAAGAGATTCATATGCTAAATTAT
TGGGTCATCAGAATTTGAAACAAAAAATCAAGCATGTTGTGAAGTTGAAAGATGAAAATAGCCAACTCAAATCGGAAGTATCAAAACTCC
GCTGTCAGCTTGCTAAAAAAAAACAAAGTGAGACAAAACTTCAAGAGGAATTGAATAAAGTTCTAGGTATCAAACACTTTGATCCTTCAA
AGGCTTTTCATCATGAAAGTAAAGAAAATTTTGCCCTGAAGACCCCATTAAAAGAAGGCAATACAAACTGTTACCGAGCTCCTATGGAGT
GTCAAGAATCATGGAAGTAAACATCTGAGAAACCTGTTGAAGATTATTTCATTCGTCTTGTTGTTATTGATGTTGCTGTTATTATATTTG
ACATGGGTATTTTATAATGTTGTATTTAATTTTAACTGCCAATCCTTAAATATGTGAAAGGAACATTTTTTACCAAAGTGTCTTTTGACA
TTTTATTTTTTCTTGCAAATACCTCCTCCCTAATGCTCACCTTTATCACCTCATTCTGAACCCTTTCGCTGGCTTTCCAGCTTAGAATGC
ATCTCATCAACTTAAAAGTCAGTATCATATTATTATCCTCCTGTTCTGAAACCTTAGTTTCAAGAGTCTAAACCCCAGATTCTTCAGCTT

>42790_42790_5_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000392272_HMMR_chr5_162890862_ENST00000353866_length(amino acids)=711AA_BP=17
MLSLLVWILTLSDTFSQGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKIRVLLQERGAQDR
RIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEM
KLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILS
KQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNL
FEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYK
ALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRK
QLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVK

--------------------------------------------------------------
>42790_42790_6_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000392272_HMMR_chr5_162890862_ENST00000393915_length(transcript)=3365nt_BP=456nt
GGCGCCGTCGGAGGGAGAGTAGACGTCAGGCGGAGGGAGGGAGGCAGGCAGGCAGGGAGGCAGGGAGGGAGAGAGGGAAGGAAGAGAAGG
GGAGAGAAAGGGGGAGCAAAGACCGAAAGAGACCCAGAGAGATACAGCTTGAGAGGAGAAATAATTAAAGGGGGAGGGCGACCAGGAGGA
GAAAAAGGTCTGGGAGGAAAGAGAGATAAAGAGAATCGGAGGGCAGGGAAATGAGTTTGTGCGCGTGAGTGTGCGCGCGCGCGTGTGTGT
GTGCAGGGGCGGGCGCGGGCGGGCGGGGGGCGGGCTCCCGGGCTCCCGGGCTCCCCTCCTCCCCAGCCCGCTCCTCTGGCTCGCTCGCCA
ACTCCGGGCCCCAGCCGCGGGCGGGCGCACGGCGGGCGGACAGCATGCTGAGCCTCCTCGTCTGGATCCTCACTCTCTCCGATACTTTCT
CCCAAGGTTGTGCACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGAT
TTAAACAGCAAAAAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAGTCTTCGGAAT
CAAAGAAGGAATCTCAAAAGAATGATAAAGATTTGAAGATATTAGAGAAAGAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACA
GGCGGATCCAGGATCTGGAAACTGAGTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGAAAAAACATCTCTCTCTGCAAATA
ATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGACTAATGAACTACTAAAATCTAAGTTTTCTGAAAATGGTAACCAGAAGAATT
TGAGAATTCTAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAACAAAGATGAGGGGTATGATGGCTAAGCAAGAAGGCATGGAGA
TGAAGCTGCAGGTCACCCAAAGGAGTCTCGAAGAGTCTCAAGGGAAAATAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAA
AGATTGATGAAAAATCTGAAACAGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGATCAAGTGGAAAAATACAAGCTAG
ATATTGCCCAGTTAGAAGAAAATTTGAAAGAGAAGAATGATGAAATTTTAAGCCTTAAGCAGTCTCTTGAGGAGAATATTGTTATATTAT
CTAAACAAGTAGAAGATCTAAATGTGAAATGTCAGCTGCTTGAAAAAGAAAAAGAAGACCATGTCAACAGGAATAGAGAACACAACGAAA
ATCTAAATGCAGAGATGCAAAACTTAAAACAGAAGTTTATTCTTGAACAACAGGAACGTGAAAAGCTTCAACAAAAAGAATTACAAATTG
ATTCACTTCTGCAACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGAAGCTCTGTTCTTTTCAAGAGGAAATGGTTAAAGAGAAGAATC
TGTTTGAGGAAGAATTAAAGCAAACACTGGATGAGCTTGATAAATTACAGCAAAAGGAGGAACAAGCTGAAAGGCTGGTCAAGCAATTGG
AAGAGGAAGCAAAATCTAGAGCTGAAGAATTAAAACTCCTAGAAGAAAAGCTGAAAGGGAAGGAGGCTGAACTGGAGAAAAGTAGTGCTG
CTCATACCCAGGCCACCCTGCTTTTGCAGGAAAAGTATGACAGTATGGTGCAAAGCCTTGAAGATGTTACTGCTCAATTTGAAAGCTATA
AAGCGTTAACAGCCAGTGAGATAGAAGATCTTAAGCTGGAGAACTCATCATTACAGGAAAAAGCGGCCAAGGCTGGGAAAAATGCAGAGG
ATGTTCAGCATCAGATTTTGGCAACTGAGAGCTCAAATCAAGAATATGTAAGGATGCTTCTAGATCTGCAGACCAAGTCAGCACTAAAGG
AAACAGAAATTAAAGAAATCACAGTTTCTTTTCTTCAAAAAATAACTGATTTGCAGAACCAACTCAAGCAACAGGAGGAAGACTTTAGAA
AACAGCTGGAAGATGAAGAAGGAAGAAAAGCTGAAAAAGAAAATACAACAGCAGAATTAACTGAAGAAATTAACAAGTGGCGTCTCCTCT
ATGAAGAACTATATAATAAAACAAAACCTTTTCAGCTACAACTAGATGCTTTTGAAGTAGAAAAACAGGCATTGTTGAATGAACATGGTG
CAGCTCAGGAACAGCTAAATAAAATAAGAGATTCATATGCTAAATTATTGGGTCATCAGAATTTGAAACAAAAAATCAAGCATGTTGTGA
AGTTGAAAGATGAAAATAGCCAACTCAAATCGGAAGTATCAAAACTCCGCTGTCAGCTTGCTAAAAAAAAACAAAGTGAGACAAAACTTC
AAGAGGAATTGAATAAAGTTCTAGGTATCAAACACTTTGATCCTTCAAAGGCTTTTCATCATGAAAGTAAAGAAAATTTTGCCCTGAAGA
CCCCATTAAAAGAAGGCAATACAAACTGTTACCGAGCTCCTATGGAGTGTCAAGAATCATGGAAGTAAACATCTGAGAAACCTGTTGAAG
ATTATTTCATTCGTCTTGTTGTTATTGATGTTGCTGTTATTATATTTGACATGGGTATTTTATAATGTTGTATTTAATTTTAACTGCCAA
TCCTTAAATATGTGAAAGGAACATTTTTTACCAAAGTGTCTTTTGACATTTTATTTTTTCTTGCAAATACCTCCTCCCTAATGCTCACCT
TTATCACCTCATTCTGAACCCTTTCGCTGGCTTTCCAGCTTAGAATGCATCTCATCAACTTAAAAGTCAGTATCATATTATTATCCTCCT
GTTCTGAAACCTTAGTTTCAAGAGTCTAAACCCCAGATTCTTCAGCTTGATCCTGGAGGTCTTTTCTAGTCTGAGCTTCTTTAGCTAGGC
TAAAACACCTTGGCTTGTTATTGCCTCTACTTTGATTCTGATAATGCTCACTTGGTCCTACCTATTATCCTTCTACTTGTCCAGTTCAAA
TAAGAAATAAGGACAAGCCTAACTTCATAGAAACCTCTCTATTTTTAATCAGTTGTTTAATAATTTACAGGTTCTTAGGCTCCATCCTGT
TTGTATGAAATTATAATCTGTGGATTGGCCTTTAAGCCTGCATTCTTAACAAACTCTTCAGTTAATTCTTAGATACACTAAAAATCTGAG
AAACTCTACATGTAACTATTTCTTCAGAGTTTGTCATATACTGCTTGTCATCTGCATGTCTACTCAGCATTTGATTAACATTTGTGTAAT

>42790_42790_6_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000392272_HMMR_chr5_162890862_ENST00000393915_length(amino acids)=727AA_BP=17
MLSLLVWILTLSDTFSQGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKKESQKNDKDLKIL
EKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKR
ETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDE
ILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLH
QKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDS
MVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI
TDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAK
LLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPM

--------------------------------------------------------------
>42790_42790_7_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000416935_HMMR_chr5_162890862_ENST00000353866_length(transcript)=2583nt_BP=84nt
AGCCGCGGGCGGGCGCACGGCGGGCGGACAGCATGCTGAGCCTCCTCGTCTGGATCCTCACTCTCTCCGATACTTTCTCCCAAGGTTGTG
CACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGATTTAAACAGCAAA
AAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAGTCTTCGGAATCAAAGATTCGTG
TTCTTCTACAGGAACGTGGTGCCCAGGACAGGCGGATCCAGGATCTGGAAACTGAGTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCAC
TAAGGGAAAAAACATCTCTCTCTGCAAATAATGCTACACTGGAAAAACAACTTATTGAATTGACCAGGACTAATGAACTACTAAAATCTA
AGTTTTCTGAAAATGGTAACCAGAAGAATTTGAGAATTCTAAGCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAACAAAGATGAGGG
GTATGATGGCTAAGCAAGAAGGCATGGAGATGAAGCTGCAGGTCACCCAAAGGAGTCTCGAAGAGTCTCAAGGGAAAATAGCCCAACTGG
AGGGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGATGAAAAATCTGAAACAGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTG
CTTCAGATCAAGTGGAAAAATACAAGCTAGATATTGCCCAGTTAGAAGAAAATTTGAAAGAGAAGAATGATGAAATTTTAAGCCTTAAGC
AGTCTCTTGAGGAGAATATTGTTATATTATCTAAACAAGTAGAAGATCTAAATGTGAAATGTCAGCTGCTTGAAAAAGAAAAAGAAGACC
ATGTCAACAGGAATAGAGAACACAACGAAAATCTAAATGCAGAGATGCAAAACTTAAAACAGAAGTTTATTCTTGAACAACAGGAACGTG
AAAAGCTTCAACAAAAAGAATTACAAATTGATTCACTTCTGCAACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGAAGCTCTGTTCTT
TTCAAGAGGAAATGGTTAAAGAGAAGAATCTGTTTGAGGAAGAATTAAAGCAAACACTGGATGAGCTTGATAAATTACAGCAAAAGGAGG
AACAAGCTGAAAGGCTGGTCAAGCAATTGGAAGAGGAAGCAAAATCTAGAGCTGAAGAATTAAAACTCCTAGAAGAAAAGCTGAAAGGGA
AGGAGGCTGAACTGGAGAAAAGTAGTGCTGCTCATACCCAGGCCACCCTGCTTTTGCAGGAAAAGTATGACAGTATGGTGCAAAGCCTTG
AAGATGTTACTGCTCAATTTGAAAGCTATAAAGCGTTAACAGCCAGTGAGATAGAAGATCTTAAGCTGGAGAACTCATCATTACAGGAAA
AAGCGGCCAAGGCTGGGAAAAATGCAGAGGATGTTCAGCATCAGATTTTGGCAACTGAGAGCTCAAATCAAGAATATGTAAGGATGCTTC
TAGATCTGCAGACCAAGTCAGCACTAAAGGAAACAGAAATTAAAGAAATCACAGTTTCTTTTCTTCAAAAAATAACTGATTTGCAGAACC
AACTCAAGCAACAGGAGGAAGACTTTAGAAAACAGCTGGAAGATGAAGAAGGAAGAAAAGCTGAAAAAGAAAATACAACAGCAGAATTAA
CTGAAGAAATTAACAAGTGGCGTCTCCTCTATGAAGAACTATATAATAAAACAAAACCTTTTCAGCTACAACTAGATGCTTTTGAAGTAG
AAAAACAGGCATTGTTGAATGAACATGGTGCAGCTCAGGAACAGCTAAATAAAATAAGAGATTCATATGCTAAATTATTGGGTCATCAGA
ATTTGAAACAAAAAATCAAGCATGTTGTGAAGTTGAAAGATGAAAATAGCCAACTCAAATCGGAAGTATCAAAACTCCGCTGTCAGCTTG
CTAAAAAAAAACAAAGTGAGACAAAACTTCAAGAGGAATTGAATAAAGTTCTAGGTATCAAACACTTTGATCCTTCAAAGGCTTTTCATC
ATGAAAGTAAAGAAAATTTTGCCCTGAAGACCCCATTAAAAGAAGGCAATACAAACTGTTACCGAGCTCCTATGGAGTGTCAAGAATCAT
GGAAGTAAACATCTGAGAAACCTGTTGAAGATTATTTCATTCGTCTTGTTGTTATTGATGTTGCTGTTATTATATTTGACATGGGTATTT
TATAATGTTGTATTTAATTTTAACTGCCAATCCTTAAATATGTGAAAGGAACATTTTTTACCAAAGTGTCTTTTGACATTTTATTTTTTC
TTGCAAATACCTCCTCCCTAATGCTCACCTTTATCACCTCATTCTGAACCCTTTCGCTGGCTTTCCAGCTTAGAATGCATCTCATCAACT
TAAAAGTCAGTATCATATTATTATCCTCCTGTTCTGAAACCTTAGTTTCAAGAGTCTAAACCCCAGATTCTTCAGCTTGATCCTGGAGGT

>42790_42790_7_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000416935_HMMR_chr5_162890862_ENST00000353866_length(amino acids)=711AA_BP=17
MLSLLVWILTLSDTFSQGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKIRVLLQERGAQDR
RIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEM
KLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILS
KQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNL
FEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYK
ALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRK
QLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVK

--------------------------------------------------------------
>42790_42790_8_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000416935_HMMR_chr5_162890862_ENST00000393915_length(transcript)=2993nt_BP=84nt
AGCCGCGGGCGGGCGCACGGCGGGCGGACAGCATGCTGAGCCTCCTCGTCTGGATCCTCACTCTCTCCGATACTTTCTCCCAAGGTTGTG
CACCATCTCCAGGTGCTTATGATGTTAAAACTTTAGAAGTATTGAAAGGACCAGTATCCTTTCAGAAATCACAAAGATTTAAACAGCAAA
AAGAATCTAAACAAAATCTTAATGTTGACAAAGATACTACCTTGCCTGCTTCAGCTAGAAAAGTTAAGTCTTCGGAATCAAAGAAGGAAT
CTCAAAAGAATGATAAAGATTTGAAGATATTAGAGAAAGAGATTCGTGTTCTTCTACAGGAACGTGGTGCCCAGGACAGGCGGATCCAGG
ATCTGGAAACTGAGTTGGAAAAGATGGAAGCAAGGCTAAATGCTGCACTAAGGGAAAAAACATCTCTCTCTGCAAATAATGCTACACTGG
AAAAACAACTTATTGAATTGACCAGGACTAATGAACTACTAAAATCTAAGTTTTCTGAAAATGGTAACCAGAAGAATTTGAGAATTCTAA
GCTTGGAGTTGATGAAACTTAGAAACAAAAGAGAAACAAAGATGAGGGGTATGATGGCTAAGCAAGAAGGCATGGAGATGAAGCTGCAGG
TCACCCAAAGGAGTCTCGAAGAGTCTCAAGGGAAAATAGCCCAACTGGAGGGAAAACTTGTTTCAATAGAGAAAGAAAAGATTGATGAAA
AATCTGAAACAGAAAAACTCTTGGAATACATCGAAGAAATTAGTTGTGCTTCAGATCAAGTGGAAAAATACAAGCTAGATATTGCCCAGT
TAGAAGAAAATTTGAAAGAGAAGAATGATGAAATTTTAAGCCTTAAGCAGTCTCTTGAGGAGAATATTGTTATATTATCTAAACAAGTAG
AAGATCTAAATGTGAAATGTCAGCTGCTTGAAAAAGAAAAAGAAGACCATGTCAACAGGAATAGAGAACACAACGAAAATCTAAATGCAG
AGATGCAAAACTTAAAACAGAAGTTTATTCTTGAACAACAGGAACGTGAAAAGCTTCAACAAAAAGAATTACAAATTGATTCACTTCTGC
AACAAGAGAAAGAATTATCTTCGAGTCTTCATCAGAAGCTCTGTTCTTTTCAAGAGGAAATGGTTAAAGAGAAGAATCTGTTTGAGGAAG
AATTAAAGCAAACACTGGATGAGCTTGATAAATTACAGCAAAAGGAGGAACAAGCTGAAAGGCTGGTCAAGCAATTGGAAGAGGAAGCAA
AATCTAGAGCTGAAGAATTAAAACTCCTAGAAGAAAAGCTGAAAGGGAAGGAGGCTGAACTGGAGAAAAGTAGTGCTGCTCATACCCAGG
CCACCCTGCTTTTGCAGGAAAAGTATGACAGTATGGTGCAAAGCCTTGAAGATGTTACTGCTCAATTTGAAAGCTATAAAGCGTTAACAG
CCAGTGAGATAGAAGATCTTAAGCTGGAGAACTCATCATTACAGGAAAAAGCGGCCAAGGCTGGGAAAAATGCAGAGGATGTTCAGCATC
AGATTTTGGCAACTGAGAGCTCAAATCAAGAATATGTAAGGATGCTTCTAGATCTGCAGACCAAGTCAGCACTAAAGGAAACAGAAATTA
AAGAAATCACAGTTTCTTTTCTTCAAAAAATAACTGATTTGCAGAACCAACTCAAGCAACAGGAGGAAGACTTTAGAAAACAGCTGGAAG
ATGAAGAAGGAAGAAAAGCTGAAAAAGAAAATACAACAGCAGAATTAACTGAAGAAATTAACAAGTGGCGTCTCCTCTATGAAGAACTAT
ATAATAAAACAAAACCTTTTCAGCTACAACTAGATGCTTTTGAAGTAGAAAAACAGGCATTGTTGAATGAACATGGTGCAGCTCAGGAAC
AGCTAAATAAAATAAGAGATTCATATGCTAAATTATTGGGTCATCAGAATTTGAAACAAAAAATCAAGCATGTTGTGAAGTTGAAAGATG
AAAATAGCCAACTCAAATCGGAAGTATCAAAACTCCGCTGTCAGCTTGCTAAAAAAAAACAAAGTGAGACAAAACTTCAAGAGGAATTGA
ATAAAGTTCTAGGTATCAAACACTTTGATCCTTCAAAGGCTTTTCATCATGAAAGTAAAGAAAATTTTGCCCTGAAGACCCCATTAAAAG
AAGGCAATACAAACTGTTACCGAGCTCCTATGGAGTGTCAAGAATCATGGAAGTAAACATCTGAGAAACCTGTTGAAGATTATTTCATTC
GTCTTGTTGTTATTGATGTTGCTGTTATTATATTTGACATGGGTATTTTATAATGTTGTATTTAATTTTAACTGCCAATCCTTAAATATG
TGAAAGGAACATTTTTTACCAAAGTGTCTTTTGACATTTTATTTTTTCTTGCAAATACCTCCTCCCTAATGCTCACCTTTATCACCTCAT
TCTGAACCCTTTCGCTGGCTTTCCAGCTTAGAATGCATCTCATCAACTTAAAAGTCAGTATCATATTATTATCCTCCTGTTCTGAAACCT
TAGTTTCAAGAGTCTAAACCCCAGATTCTTCAGCTTGATCCTGGAGGTCTTTTCTAGTCTGAGCTTCTTTAGCTAGGCTAAAACACCTTG
GCTTGTTATTGCCTCTACTTTGATTCTGATAATGCTCACTTGGTCCTACCTATTATCCTTCTACTTGTCCAGTTCAAATAAGAAATAAGG
ACAAGCCTAACTTCATAGAAACCTCTCTATTTTTAATCAGTTGTTTAATAATTTACAGGTTCTTAGGCTCCATCCTGTTTGTATGAAATT
ATAATCTGTGGATTGGCCTTTAAGCCTGCATTCTTAACAAACTCTTCAGTTAATTCTTAGATACACTAAAAATCTGAGAAACTCTACATG
TAACTATTTCTTCAGAGTTTGTCATATACTGCTTGTCATCTGCATGTCTACTCAGCATTTGATTAACATTTGTGTAATATGAAATAAAAT

>42790_42790_8_KIRREL-HMMR_KIRREL_chr1_157963518_ENST00000416935_HMMR_chr5_162890862_ENST00000393915_length(amino acids)=727AA_BP=17
MLSLLVWILTLSDTFSQGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKKESQKNDKDLKIL
EKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKR
ETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDE
ILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLH
QKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDS
MVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKI
TDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAK
LLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPM

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for KIRREL-HMMR

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for KIRREL-HMMR

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for KIRREL-HMMR

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source