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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KLF15-SLC41A3 (FusionGDB2 ID:42864)

Fusion Gene Summary for KLF15-SLC41A3

check button Fusion gene summary
Fusion gene informationFusion gene name: KLF15-SLC41A3
Fusion gene ID: 42864
HgeneTgene
Gene symbol

KLF15

SLC41A3

Gene ID

28999

54946

Gene nameKruppel like factor 15solute carrier family 41 member 3
SynonymsKKLFSLC41A1-L2
Cytomap

3q21.3

3q21.2-q21.3

Type of geneprotein-codingprotein-coding
DescriptionKrueppel-like factor 15kidney-enriched Kruppel-like factorkidney-enriched krueppel-like factorsolute carrier family 41 member 3SLC41A1-like 2
Modification date2020032720200313
UniProtAcc

Q9UIH9

.
Ensembl transtripts involved in fusion geneENST00000296233, ENST00000509675, 
ENST00000514023, ENST00000315891, 
ENST00000346785, ENST00000360370, 
ENST00000383598, ENST00000508835, 
Fusion gene scores* DoF score3 X 2 X 3=189 X 7 X 7=441
# samples 39
** MAII scorelog2(3/18*10)=0.736965594166206
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(9/441*10)=-2.29278174922785
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KLF15 [Title/Abstract] AND SLC41A3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKLF15(126070684)-SLC41A3(125752521), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across KLF15 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC41A3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PRADTCGA-G9-6377-01AKLF15chr3

126070684

-SLC41A3chr3

125752521

-


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Fusion Gene ORF analysis for KLF15-SLC41A3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000296233ENST00000514023KLF15chr3

126070684

-SLC41A3chr3

125752521

-
In-frameENST00000296233ENST00000315891KLF15chr3

126070684

-SLC41A3chr3

125752521

-
In-frameENST00000296233ENST00000346785KLF15chr3

126070684

-SLC41A3chr3

125752521

-
In-frameENST00000296233ENST00000360370KLF15chr3

126070684

-SLC41A3chr3

125752521

-
In-frameENST00000296233ENST00000383598KLF15chr3

126070684

-SLC41A3chr3

125752521

-
In-frameENST00000296233ENST00000508835KLF15chr3

126070684

-SLC41A3chr3

125752521

-
intron-3CDSENST00000509675ENST00000315891KLF15chr3

126070684

-SLC41A3chr3

125752521

-
intron-3CDSENST00000509675ENST00000346785KLF15chr3

126070684

-SLC41A3chr3

125752521

-
intron-3CDSENST00000509675ENST00000360370KLF15chr3

126070684

-SLC41A3chr3

125752521

-
intron-3CDSENST00000509675ENST00000383598KLF15chr3

126070684

-SLC41A3chr3

125752521

-
intron-3CDSENST00000509675ENST00000508835KLF15chr3

126070684

-SLC41A3chr3

125752521

-
intron-5UTRENST00000509675ENST00000514023KLF15chr3

126070684

-SLC41A3chr3

125752521

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000296233KLF15chr3126070684-ENST00000360370SLC41A3chr3125752521-305713131930419503
ENST00000296233KLF15chr3126070684-ENST00000346785SLC41A3chr3125752521-250613131930419503
ENST00000296233KLF15chr3126070684-ENST00000383598SLC41A3chr3125752521-305413131930419503
ENST00000296233KLF15chr3126070684-ENST00000315891SLC41A3chr3125752521-249013131930419503
ENST00000296233KLF15chr3126070684-ENST00000508835SLC41A3chr3125752521-255613131930419503

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000296233ENST00000360370KLF15chr3126070684-SLC41A3chr3125752521-0.221005160.77899486
ENST00000296233ENST00000346785KLF15chr3126070684-SLC41A3chr3125752521-0.213759390.78624064
ENST00000296233ENST00000383598KLF15chr3126070684-SLC41A3chr3125752521-0.221804540.7781955
ENST00000296233ENST00000315891KLF15chr3126070684-SLC41A3chr3125752521-0.214706260.7852937
ENST00000296233ENST00000508835KLF15chr3126070684-SLC41A3chr3125752521-0.186873630.8131264

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Fusion Genomic Features for KLF15-SLC41A3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KLF15-SLC41A3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:126070684/chr3:125752521)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KLF15

Q9UIH9

.
FUNCTION: Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart (By similarity). Is a repressor of CCN2 expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 (By similarity). Involved in podocyte differentiation (By similarity). Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation. {ECO:0000250, ECO:0000269|PubMed:18586263, ECO:0000269|PubMed:20375365, ECO:0000269|PubMed:20566642, ECO:0000269|PubMed:23999430}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKLF15chr3:126070684chr3:125752521ENST00000296233-2375_83360417.0Motif9aaTAD
HgeneKLF15chr3:126070684chr3:125752521ENST00000296233-23321_345360417.0Zinc fingerC2H2-type 1
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212378_381127508.0Compositional biasNote=Poly-Leu
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111378_38191472.0Compositional biasNote=Poly-Leu
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110378_381101462.0Compositional biasNote=Poly-Leu
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110378_38110371.0Compositional biasNote=Poly-Leu
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212152_172127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212189_209127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212220_240127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212252_272127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212284_304127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212314_334127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212377_397127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212406_426127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000315891212482_502127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111152_17291472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111189_20991472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111220_24091472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111252_27291472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111284_30491472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111314_33491472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111377_39791472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111406_42691472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000346785111482_50291472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110152_172101462.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110189_209101462.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110220_240101462.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110252_272101462.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110284_304101462.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110314_334101462.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110377_397101462.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110406_426101462.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000383598110482_502101462.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110152_17210371.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110189_20910371.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110220_24010371.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110252_27210371.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110284_30410371.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110314_33410371.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110377_39710371.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110406_42610371.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST00000508835110482_50210371.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST0000050883511067_8710371.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKLF15chr3:126070684chr3:125752521ENST00000296233-23351_375360417.0Zinc fingerC2H2-type 2
HgeneKLF15chr3:126070684chr3:125752521ENST00000296233-23381_403360417.0Zinc fingerC2H2-type 3
TgeneSLC41A3chr3:126070684chr3:125752521ENST0000031589121267_87127508.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST0000034678511167_8791472.0TransmembraneHelical
TgeneSLC41A3chr3:126070684chr3:125752521ENST0000038359811067_87101462.0TransmembraneHelical


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Fusion Gene Sequence for KLF15-SLC41A3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42864_42864_1_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000315891_length(transcript)=2490nt_BP=1313nt
GGGGAGTGAGTGCCCAGCGAGCTGCGGGCGGGCTAGTGCTCCGCCGCAGCGACCCGCGGGCCGGCGGGCGATCGAGCCAGCGCAGGACCC
GCGGCTCGGCCCCCGGCCGCCGCCGGACCGAGAGTCTAGCCGCCGCCCCCAGCCCAGCCCGCCCGGCCGCAGGACCGCCGGGGCCTGGCC
GCCGGTCCGGCGTGCGCCAAGTTCAGCCGCCACCGGCACGGCCAGGCCAGCATGGTGGACCACTTACTTCCAGTGGACGAGAACTTCTCG
TCGCCAAAATGCCCAGTTGGGTATCTGGGTGATAGGCTGGTTGGCCGGCGGGCATATCACATGCTGCCCTCACCCGTCTCTGAAGATGAC
AGCGATGCCTCCAGCCCCTGCTCCTGTTCCAGTCCCGACTCTCAAGCCCTCTGCTCCTGCTATGGTGGAGGCCTGGGCACCGAGAGCCAG
GACAGCATCTTGGACTTCCTATTGTCCCAGGCCACGCTGGGCAGTGGCGGGGGCAGCGGCAGTAGCATTGGGGCCAGCAGTGGCCCCGTG
GCCTGGGGGCCCTGGCGAAGGGCAGCGGCCCCTGTGAAGGGGGAGCATTTCTGCTTGCCCGAGTTTCCTTTGGGTGATCCTGATGACGTC
CCACGGCCCTTCCAGCCTACCCTGGAGGAGATTGAAGAGTTTCTGGAGGAGAACATGGAGCCTGGAGTCAAGGAGGTCCCTGAGGGCAAC
AGCAAGGACTTGGATGCCTGCAGCCAGCTCTCAGCTGGGCCACACAAGAGCCACCTCCATCCTGGGTCCAGCGGGAGAGAGCGCTGTTCC
CCTCCACCAGGTGGTGCCAGTGCAGGAGGTGCCCAGGGCCCAGGTGGGGGCCCCACGCCTGATGGCCCCATCCCAGTGTTGCTGCAGATC
CAGCCCGTGCCTGTGAAGCAGGAATCGGGCACAGGGCCTGCCTCCCCTGGGCAAGCCCCAGAGAATGTCAAGGTTGCCCAGCTCCTGGTC
AACATCCAGGGGCAGACCTTCGCACTCGTGCCCCAGGTGGTACCCTCCTCCAACTTGAACCTGCCCTCCAAGTTTGTGCGCATTGCCCCT
GTGCCCATTGCCGCCAAGCCTGTTGGATCGGGACCCCTGGGGCCTGGCCCTGCCGGTCTCCTCATGGGCCAGAAGTTCCCCAAGAACCCA
GCCGCAGAACTCATCAAAATGCACAAATGTACTTTCCCTGGCTGCAGCAAGATGTACACCAAAAGCAGCCACCTCAAGGCCCACCTGCGC
CGGCACACGGGTGAGAAGCCCTTCGCCTGCACCTGGCCAGGCTGCGGCTGGAGGCCAACACTGGACAAATTGATGACCCCCAGGAGCAGC
ACAGAGTCATCAGCAGCAACCTGGCCCTCATCCAGGTGCAGGCCACTGTCGTGGGGCTCTTGGCTGCTGTGGCTGCGCTGCTGTTGGGCG
TGGTGTCTCGAGAGGAAGTGGATGTCGCCAAGGTGGAGTTGCTGTGTGCCAGCAGTGTCCTCACTGCCTTCCTTGCAGCCTTTGCCCTGG
GGGTGCTGATGGTCTGTATAGTGATTGGTGCTCGAAAGCTCGGGGTCAACCCAGACAACATTGCCACGCCCATTGCAGCCAGCCTGGGAG
ACCTCATCACACTGTCCATTCTGGCTTTGGTTAGCAGCTTCTTCTACAGACACAAAGATAGTCGGTATCTGACGCCGCTGGTCTGCCTCA
GCTTTGCGGCTCTGACCCCAGTGTGGGTCCTCATTGCCAAGCAGAGCCCACCCATCGTGAAGATCCTGAAGTTTGGCTGGTTCCCAATCA
TCCTGGCCATGGTCATCAGCAGTTTCGGAGGACTCATCTTGAGCAAAACCGTTTCTAAACAGCAGTACAAAGGCATGGCGATATTTACCC
CCGTCATATGTGGTGTTGGTGGCAATCTGGTGGCCATTCAGACCAGCCGAATCTCAACCTACCTGCACATGTGGAGTGCACCTGGCGTCC
TGCCCCTCCAGATGAAGAAATTCTGGCCCAACCCGTGTTCTACTTTCTGCACGTCAGAAATCAATTCCATGTCAGCTCGAGTCCTGCTCT
TGCTGGTGGTCCCAGGCCATCTGATTTTCTTCTACATCATCTACCTGGTGGAGGGTCAGTCAGTCATAAACAGCCAGACCTTTGTGGTGC
TCTACCTGCTGGCAGGCCTGATCCAGGTGACAATCCTGCTGTACCTCGCAGAAGTGATGGTTCGGCTGACTTGGCACCAGGCCCTGGATC
CTGACAACCACTGCATCCCCTACCTTACAGGGCTGGGGGACCTGCTCGGTTCAAGCTCCGTGGGCCACACTGCTGCTGTGCCAAGAAGGT
GTACAGCCTCCCCAGGATGGGGCCTCATACAACCCTTCATCTGCACTCAACATTTAATCGTGTCCTTGCTGTCTTTTTATTTTCCTTTTT

>42864_42864_1_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000315891_length(amino acids)=503AA_BP=1
MNGHQIATNTTYDGGKYRHAFVLLFRNGFAQDESSETADDHGQDDWEPAKLQDLHDGWALLGNEDPHWGQSRKAEADQRRQIPTIFVSVE
EAANQSQNGQCDEVSQAGCNGRGNVVWVDPELSSTNHYTDHQHPQGKGCKEGSEDTAGTQQLHLGDIHFLSRHHAQQQRSHSSQEPHDSG
LHLDEGQVAADDSVLLLGVINLSSVGLQPQPGQVQAKGFSPVCRRRWALRWLLLVYILLQPGKVHLCILMSSAAGFLGNFWPMRRPAGPG
PRGPDPTGLAAMGTGAMRTNLEGRFKLEEGTTWGTSAKVCPWMLTRSWATLTFSGACPGEAGPVPDSCFTGTGWICSNTGMGPSGVGPPP
GPWAPPALAPPGGGEQRSLPLDPGWRWLLCGPAESWLQASKSLLLPSGTSLTPGSMFSSRNSSISSRVGWKGRGTSSGSPKGNSGKQKCS

--------------------------------------------------------------
>42864_42864_2_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000346785_length(transcript)=2506nt_BP=1313nt
GGGGAGTGAGTGCCCAGCGAGCTGCGGGCGGGCTAGTGCTCCGCCGCAGCGACCCGCGGGCCGGCGGGCGATCGAGCCAGCGCAGGACCC
GCGGCTCGGCCCCCGGCCGCCGCCGGACCGAGAGTCTAGCCGCCGCCCCCAGCCCAGCCCGCCCGGCCGCAGGACCGCCGGGGCCTGGCC
GCCGGTCCGGCGTGCGCCAAGTTCAGCCGCCACCGGCACGGCCAGGCCAGCATGGTGGACCACTTACTTCCAGTGGACGAGAACTTCTCG
TCGCCAAAATGCCCAGTTGGGTATCTGGGTGATAGGCTGGTTGGCCGGCGGGCATATCACATGCTGCCCTCACCCGTCTCTGAAGATGAC
AGCGATGCCTCCAGCCCCTGCTCCTGTTCCAGTCCCGACTCTCAAGCCCTCTGCTCCTGCTATGGTGGAGGCCTGGGCACCGAGAGCCAG
GACAGCATCTTGGACTTCCTATTGTCCCAGGCCACGCTGGGCAGTGGCGGGGGCAGCGGCAGTAGCATTGGGGCCAGCAGTGGCCCCGTG
GCCTGGGGGCCCTGGCGAAGGGCAGCGGCCCCTGTGAAGGGGGAGCATTTCTGCTTGCCCGAGTTTCCTTTGGGTGATCCTGATGACGTC
CCACGGCCCTTCCAGCCTACCCTGGAGGAGATTGAAGAGTTTCTGGAGGAGAACATGGAGCCTGGAGTCAAGGAGGTCCCTGAGGGCAAC
AGCAAGGACTTGGATGCCTGCAGCCAGCTCTCAGCTGGGCCACACAAGAGCCACCTCCATCCTGGGTCCAGCGGGAGAGAGCGCTGTTCC
CCTCCACCAGGTGGTGCCAGTGCAGGAGGTGCCCAGGGCCCAGGTGGGGGCCCCACGCCTGATGGCCCCATCCCAGTGTTGCTGCAGATC
CAGCCCGTGCCTGTGAAGCAGGAATCGGGCACAGGGCCTGCCTCCCCTGGGCAAGCCCCAGAGAATGTCAAGGTTGCCCAGCTCCTGGTC
AACATCCAGGGGCAGACCTTCGCACTCGTGCCCCAGGTGGTACCCTCCTCCAACTTGAACCTGCCCTCCAAGTTTGTGCGCATTGCCCCT
GTGCCCATTGCCGCCAAGCCTGTTGGATCGGGACCCCTGGGGCCTGGCCCTGCCGGTCTCCTCATGGGCCAGAAGTTCCCCAAGAACCCA
GCCGCAGAACTCATCAAAATGCACAAATGTACTTTCCCTGGCTGCAGCAAGATGTACACCAAAAGCAGCCACCTCAAGGCCCACCTGCGC
CGGCACACGGGTGAGAAGCCCTTCGCCTGCACCTGGCCAGGCTGCGGCTGGAGGCCAACACTGGACAAATTGATGACCCCCAGGAGCAGC
ACAGAGTCATCAGCAGCAACCTGGCCCTCATCCAGGTGCAGGCCACTGTCGTGGGGCTCTTGGCTGCTGTGGCTGCGCTGCTGTTGGGCG
TGGTGTCTCGAGAGGAAGTGGATGTCGCCAAGGTGGAGTTGCTGTGTGCCAGCAGTGTCCTCACTGCCTTCCTTGCAGCCTTTGCCCTGG
GGGTGCTGATGGTCTGTATAGTGATTGGTGCTCGAAAGCTCGGGGTCAACCCAGACAACATTGCCACGCCCATTGCAGCCAGCCTGGGAG
ACCTCATCACACTGTCCATTCTGGCTTTGGTTAGCAGCTTCTTCTACAGACACAAAGATAGTCGGTATCTGACGCCGCTGGTCTGCCTCA
GCTTTGCGGCTCTGACCCCAGTGTGGGTCCTCATTGCCAAGCAGAGCCCACCCATCGTGAAGATCCTGAAGTTTGGCTGGTTCCCAATCA
TCCTGGCCATGGTCATCAGCAGTTTCGGAGGACTCATCTTGAGCAAAACCGTTTCTAAACAGCAGTACAAAGGCATGGCGATATTTACCC
CCGTCATATGTGGTGTTGGTGGCAATCTGGTGGCCATTCAGACCAGCCGAATCTCAACCTACCTGCACATGTGGAGTGCACCTGGCGTCC
TGCCCCTCCAGATGAAGAAATTCTGGCCCAACCCGTGTTCTACTTTCTGCACGTCAGAAATCAATTCCATGTCAGCTCGAGTCCTGCTCT
TGCTGGTGGTCCCAGGCCATCTGATTTTCTTCTACATCATCTACCTGGTGGAGGGTCAGTCAGTCATAAACAGCCAGACCTTTGTGGTGC
TCTACCTGCTGGCAGGCCTGATCCAGGTGACAATCCTGCTGTACCTCGCAGAAGTGATGGTTCGGCTGACTTGGCACCAGGCCCTGGATC
CTGACAACCACTGCATCCCCTACCTTACAGGGCTGGGGGACCTGCTCGGTTCAAGCTCCGTGGGCCACACTGCTGCTGTGCCAAGAAGGT
GTACAGCCTCCCCAGGATGGGGCCTCATACAACCCTTCATCTGCACTCAACATTTAATCGTGTCCTTGCTGTCTTTTTATTTTCCTTTTT

>42864_42864_2_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000346785_length(amino acids)=503AA_BP=1
MNGHQIATNTTYDGGKYRHAFVLLFRNGFAQDESSETADDHGQDDWEPAKLQDLHDGWALLGNEDPHWGQSRKAEADQRRQIPTIFVSVE
EAANQSQNGQCDEVSQAGCNGRGNVVWVDPELSSTNHYTDHQHPQGKGCKEGSEDTAGTQQLHLGDIHFLSRHHAQQQRSHSSQEPHDSG
LHLDEGQVAADDSVLLLGVINLSSVGLQPQPGQVQAKGFSPVCRRRWALRWLLLVYILLQPGKVHLCILMSSAAGFLGNFWPMRRPAGPG
PRGPDPTGLAAMGTGAMRTNLEGRFKLEEGTTWGTSAKVCPWMLTRSWATLTFSGACPGEAGPVPDSCFTGTGWICSNTGMGPSGVGPPP
GPWAPPALAPPGGGEQRSLPLDPGWRWLLCGPAESWLQASKSLLLPSGTSLTPGSMFSSRNSSISSRVGWKGRGTSSGSPKGNSGKQKCS

--------------------------------------------------------------
>42864_42864_3_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000360370_length(transcript)=3057nt_BP=1313nt
GGGGAGTGAGTGCCCAGCGAGCTGCGGGCGGGCTAGTGCTCCGCCGCAGCGACCCGCGGGCCGGCGGGCGATCGAGCCAGCGCAGGACCC
GCGGCTCGGCCCCCGGCCGCCGCCGGACCGAGAGTCTAGCCGCCGCCCCCAGCCCAGCCCGCCCGGCCGCAGGACCGCCGGGGCCTGGCC
GCCGGTCCGGCGTGCGCCAAGTTCAGCCGCCACCGGCACGGCCAGGCCAGCATGGTGGACCACTTACTTCCAGTGGACGAGAACTTCTCG
TCGCCAAAATGCCCAGTTGGGTATCTGGGTGATAGGCTGGTTGGCCGGCGGGCATATCACATGCTGCCCTCACCCGTCTCTGAAGATGAC
AGCGATGCCTCCAGCCCCTGCTCCTGTTCCAGTCCCGACTCTCAAGCCCTCTGCTCCTGCTATGGTGGAGGCCTGGGCACCGAGAGCCAG
GACAGCATCTTGGACTTCCTATTGTCCCAGGCCACGCTGGGCAGTGGCGGGGGCAGCGGCAGTAGCATTGGGGCCAGCAGTGGCCCCGTG
GCCTGGGGGCCCTGGCGAAGGGCAGCGGCCCCTGTGAAGGGGGAGCATTTCTGCTTGCCCGAGTTTCCTTTGGGTGATCCTGATGACGTC
CCACGGCCCTTCCAGCCTACCCTGGAGGAGATTGAAGAGTTTCTGGAGGAGAACATGGAGCCTGGAGTCAAGGAGGTCCCTGAGGGCAAC
AGCAAGGACTTGGATGCCTGCAGCCAGCTCTCAGCTGGGCCACACAAGAGCCACCTCCATCCTGGGTCCAGCGGGAGAGAGCGCTGTTCC
CCTCCACCAGGTGGTGCCAGTGCAGGAGGTGCCCAGGGCCCAGGTGGGGGCCCCACGCCTGATGGCCCCATCCCAGTGTTGCTGCAGATC
CAGCCCGTGCCTGTGAAGCAGGAATCGGGCACAGGGCCTGCCTCCCCTGGGCAAGCCCCAGAGAATGTCAAGGTTGCCCAGCTCCTGGTC
AACATCCAGGGGCAGACCTTCGCACTCGTGCCCCAGGTGGTACCCTCCTCCAACTTGAACCTGCCCTCCAAGTTTGTGCGCATTGCCCCT
GTGCCCATTGCCGCCAAGCCTGTTGGATCGGGACCCCTGGGGCCTGGCCCTGCCGGTCTCCTCATGGGCCAGAAGTTCCCCAAGAACCCA
GCCGCAGAACTCATCAAAATGCACAAATGTACTTTCCCTGGCTGCAGCAAGATGTACACCAAAAGCAGCCACCTCAAGGCCCACCTGCGC
CGGCACACGGGTGAGAAGCCCTTCGCCTGCACCTGGCCAGGCTGCGGCTGGAGGCCAACACTGGACAAATTGATGACCCCCAGGAGCAGC
ACAGAGTCATCAGCAGCAACCTGGCCCTCATCCAGGTGCAGGCCACTGTCGTGGGGCTCTTGGCTGCTGTGGCTGCGCTGCTGTTGGGCG
TGGTGTCTCGAGAGGAAGTGGATGTCGCCAAGGTGGAGTTGCTGTGTGCCAGCAGTGTCCTCACTGCCTTCCTTGCAGCCTTTGCCCTGG
GGGTGCTGATGGTCTGTATAGTGATTGGTGCTCGAAAGCTCGGGGTCAACCCAGACAACATTGCCACGCCCATTGCAGCCAGCCTGGGAG
ACCTCATCACACTGTCCATTCTGGCTTTGGTTAGCAGCTTCTTCTACAGACACAAAGATAGTCGGTATCTGACGCCGCTGGTCTGCCTCA
GCTTTGCGGCTCTGACCCCAGTGTGGGTCCTCATTGCCAAGCAGAGCCCACCCATCGTGAAGATCCTGAAGTTTGGCTGGTTCCCAATCA
TCCTGGCCATGGTCATCAGCAGTTTCGGAGGACTCATCTTGAGCAAAACCGTTTCTAAACAGCAGTACAAAGGCATGGCGATATTTACCC
CCGTCATATGTGGTGTTGGTGGCAATCTGGTGGCCATTCAGACCAGCCGAATCTCAACCTACCTGCACATGTGGAGTGCACCTGGCGTCC
TGCCCCTCCAGATGAAGAAATTCTGGCCCAACCCGTGTTCTACTTTCTGCACGTCAGAAATCAATTCCATGTCAGCTCGAGTCCTGCTCT
TGCTGGTGGTCCCAGGCCATCTGATTTTCTTCTACATCATCTACCTGGTGGAGGGTCAGTCAGTCATAAACAGCCAGACCTTTGTGGTGC
TCTACCTGCTGGCAGGCCTGATCCAGGTGACAATCCTGCTGTACCTCGCAGAAGTGATGGTTCGGCTGACTTGGCACCAGGCCCTGGATC
CTGACAACCACTGCATCCCCTACCTTACAGGGCTGGGGGACCTGCTCGGTACTGGCCTCCTGGCACTCTGCTTTTTCACTGACTGGCTAC
TGAAGAGCAAGGCAGAGCTGGGTGGCATCTCAGAACTGGCATCTGGACCTCCCTAACTGGGCCCCGCTGGTCCCATTTGCTCATTAGAAT
TTCCTCTCACATCAGTGGGATACAGAATTCAGTTTCTCCCTTGCCAGGTCCTTGGGATGGTTGACCCCTGCCTCTGCAGTAGCCTTTTGT
GAGTCTGCTAAGGTAGCTCTCACACACCTCGGCTCTGGGGTTGATACCTGAGCCTGCAATAGAGCCCTGAAATCAAGAGCATGGCTTGAG
TGTGTGAATATGATGTGTGCACATGCTTAATGAGCGTGCAAGTGTGCACACGTTTGTGGAGAGGAGGGTGTTCTGGCCTGAGAAGGTAAA
GAAGAGGCATGTCCAGTATGCTTTGCAGGGTGTGTTTGCTCTTTTCCATGCCCATGCAACCCAGATTGGGGTGGAGCAGGAAGGAGCTCT
TTTCTGTTCCCAAGCCTCAGAACTCTTGAGCTGTGGCTTACTTGCTGTCTTCACCAGGTTCAAGCTCCGTGGGCCACACTGCTGCTGTGC
CAAGAAGGTGTACAGCCTCCCCAGGATGGGGCCTCATACAACCCTTCATCTGCACTCAACATTTAATCGTGTCCTTGCTGTCTTTTTATT

>42864_42864_3_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000360370_length(amino acids)=503AA_BP=1
MNGHQIATNTTYDGGKYRHAFVLLFRNGFAQDESSETADDHGQDDWEPAKLQDLHDGWALLGNEDPHWGQSRKAEADQRRQIPTIFVSVE
EAANQSQNGQCDEVSQAGCNGRGNVVWVDPELSSTNHYTDHQHPQGKGCKEGSEDTAGTQQLHLGDIHFLSRHHAQQQRSHSSQEPHDSG
LHLDEGQVAADDSVLLLGVINLSSVGLQPQPGQVQAKGFSPVCRRRWALRWLLLVYILLQPGKVHLCILMSSAAGFLGNFWPMRRPAGPG
PRGPDPTGLAAMGTGAMRTNLEGRFKLEEGTTWGTSAKVCPWMLTRSWATLTFSGACPGEAGPVPDSCFTGTGWICSNTGMGPSGVGPPP
GPWAPPALAPPGGGEQRSLPLDPGWRWLLCGPAESWLQASKSLLLPSGTSLTPGSMFSSRNSSISSRVGWKGRGTSSGSPKGNSGKQKCS

--------------------------------------------------------------
>42864_42864_4_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000383598_length(transcript)=3054nt_BP=1313nt
GGGGAGTGAGTGCCCAGCGAGCTGCGGGCGGGCTAGTGCTCCGCCGCAGCGACCCGCGGGCCGGCGGGCGATCGAGCCAGCGCAGGACCC
GCGGCTCGGCCCCCGGCCGCCGCCGGACCGAGAGTCTAGCCGCCGCCCCCAGCCCAGCCCGCCCGGCCGCAGGACCGCCGGGGCCTGGCC
GCCGGTCCGGCGTGCGCCAAGTTCAGCCGCCACCGGCACGGCCAGGCCAGCATGGTGGACCACTTACTTCCAGTGGACGAGAACTTCTCG
TCGCCAAAATGCCCAGTTGGGTATCTGGGTGATAGGCTGGTTGGCCGGCGGGCATATCACATGCTGCCCTCACCCGTCTCTGAAGATGAC
AGCGATGCCTCCAGCCCCTGCTCCTGTTCCAGTCCCGACTCTCAAGCCCTCTGCTCCTGCTATGGTGGAGGCCTGGGCACCGAGAGCCAG
GACAGCATCTTGGACTTCCTATTGTCCCAGGCCACGCTGGGCAGTGGCGGGGGCAGCGGCAGTAGCATTGGGGCCAGCAGTGGCCCCGTG
GCCTGGGGGCCCTGGCGAAGGGCAGCGGCCCCTGTGAAGGGGGAGCATTTCTGCTTGCCCGAGTTTCCTTTGGGTGATCCTGATGACGTC
CCACGGCCCTTCCAGCCTACCCTGGAGGAGATTGAAGAGTTTCTGGAGGAGAACATGGAGCCTGGAGTCAAGGAGGTCCCTGAGGGCAAC
AGCAAGGACTTGGATGCCTGCAGCCAGCTCTCAGCTGGGCCACACAAGAGCCACCTCCATCCTGGGTCCAGCGGGAGAGAGCGCTGTTCC
CCTCCACCAGGTGGTGCCAGTGCAGGAGGTGCCCAGGGCCCAGGTGGGGGCCCCACGCCTGATGGCCCCATCCCAGTGTTGCTGCAGATC
CAGCCCGTGCCTGTGAAGCAGGAATCGGGCACAGGGCCTGCCTCCCCTGGGCAAGCCCCAGAGAATGTCAAGGTTGCCCAGCTCCTGGTC
AACATCCAGGGGCAGACCTTCGCACTCGTGCCCCAGGTGGTACCCTCCTCCAACTTGAACCTGCCCTCCAAGTTTGTGCGCATTGCCCCT
GTGCCCATTGCCGCCAAGCCTGTTGGATCGGGACCCCTGGGGCCTGGCCCTGCCGGTCTCCTCATGGGCCAGAAGTTCCCCAAGAACCCA
GCCGCAGAACTCATCAAAATGCACAAATGTACTTTCCCTGGCTGCAGCAAGATGTACACCAAAAGCAGCCACCTCAAGGCCCACCTGCGC
CGGCACACGGGTGAGAAGCCCTTCGCCTGCACCTGGCCAGGCTGCGGCTGGAGGCCAACACTGGACAAATTGATGACCCCCAGGAGCAGC
ACAGAGTCATCAGCAGCAACCTGGCCCTCATCCAGGTGCAGGCCACTGTCGTGGGGCTCTTGGCTGCTGTGGCTGCGCTGCTGTTGGGCG
TGGTGTCTCGAGAGGAAGTGGATGTCGCCAAGGTGGAGTTGCTGTGTGCCAGCAGTGTCCTCACTGCCTTCCTTGCAGCCTTTGCCCTGG
GGGTGCTGATGGTCTGTATAGTGATTGGTGCTCGAAAGCTCGGGGTCAACCCAGACAACATTGCCACGCCCATTGCAGCCAGCCTGGGAG
ACCTCATCACACTGTCCATTCTGGCTTTGGTTAGCAGCTTCTTCTACAGACACAAAGATAGTCGGTATCTGACGCCGCTGGTCTGCCTCA
GCTTTGCGGCTCTGACCCCAGTGTGGGTCCTCATTGCCAAGCAGAGCCCACCCATCGTGAAGATCCTGAAGTTTGGCTGGTTCCCAATCA
TCCTGGCCATGGTCATCAGCAGTTTCGGAGGACTCATCTTGAGCAAAACCGTTTCTAAACAGCAGTACAAAGGCATGGCGATATTTACCC
CCGTCATATGTGGTGTTGGTGGCAATCTGGTGGCCATTCAGACCAGCCGAATCTCAACCTACCTGCACATGTGGAGTGCACCTGGCGTCC
TGCCCCTCCAGATGAAGAAATTCTGGCCCAACCCGTGTTCTACTTTCTGCACGTCAGAAATCAATTCCATGTCAGCTCGAGTCCTGCTCT
TGCTGGTGGTCCCAGGCCATCTGATTTTCTTCTACATCATCTACCTGGTGGAGGGTCAGTCAGTCATAAACAGCCAGACCTTTGTGGTGC
TCTACCTGCTGGCAGGCCTGATCCAGGTGACAATCCTGCTGTACCTCGCAGAAGTGATGGTTCGGCTGACTTGGCACCAGGCCCTGGATC
CTGACAACCACTGCATCCCCTACCTTACAGGGCTGGGGGACCTGCTCGGTACTGGCCTCCTGGCACTCTGCTTTTTCACTGACTGGCTAC
TGAAGAGCAAGGCAGAGCTGGGTGGCATCTCAGAACTGGCATCTGGACCTCCCTAACTGGGCCCCGCTGGTCCCATTTGCTCATTAGAAT
TTCCTCTCACATCAGTGGGATACAGAATTCAGTTTCTCCCTTGCCAGGTCCTTGGGATGGTTGACCCCTGCCTCTGCAGTAGCCTTTTGT
GAGTCTGCTAAGGTAGCTCTCACACACCTCGGCTCTGGGGTTGATACCTGAGCCTGCAATAGAGCCCTGAAATCAAGAGCATGGCTTGAG
TGTGTGAATATGATGTGTGCACATGCTTAATGAGCGTGCAAGTGTGCACACGTTTGTGGAGAGGAGGGTGTTCTGGCCTGAGAAGGTAAA
GAAGAGGCATGTCCAGTATGCTTTGCAGGGTGTGTTTGCTCTTTTCCATGCCCATGCAACCCAGATTGGGGTGGAGCAGGAAGGAGCTCT
TTTCTGTTCCCAAGCCTCAGAACTCTTGAGCTGTGGCTTACTTGCTGTCTTCACCAGGTTCAAGCTCCGTGGGCCACACTGCTGCTGTGC
CAAGAAGGTGTACAGCCTCCCCAGGATGGGGCCTCATACAACCCTTCATCTGCACTCAACATTTAATCGTGTCCTTGCTGTCTTTTTATT

>42864_42864_4_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000383598_length(amino acids)=503AA_BP=1
MNGHQIATNTTYDGGKYRHAFVLLFRNGFAQDESSETADDHGQDDWEPAKLQDLHDGWALLGNEDPHWGQSRKAEADQRRQIPTIFVSVE
EAANQSQNGQCDEVSQAGCNGRGNVVWVDPELSSTNHYTDHQHPQGKGCKEGSEDTAGTQQLHLGDIHFLSRHHAQQQRSHSSQEPHDSG
LHLDEGQVAADDSVLLLGVINLSSVGLQPQPGQVQAKGFSPVCRRRWALRWLLLVYILLQPGKVHLCILMSSAAGFLGNFWPMRRPAGPG
PRGPDPTGLAAMGTGAMRTNLEGRFKLEEGTTWGTSAKVCPWMLTRSWATLTFSGACPGEAGPVPDSCFTGTGWICSNTGMGPSGVGPPP
GPWAPPALAPPGGGEQRSLPLDPGWRWLLCGPAESWLQASKSLLLPSGTSLTPGSMFSSRNSSISSRVGWKGRGTSSGSPKGNSGKQKCS

--------------------------------------------------------------
>42864_42864_5_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000508835_length(transcript)=2556nt_BP=1313nt
GGGGAGTGAGTGCCCAGCGAGCTGCGGGCGGGCTAGTGCTCCGCCGCAGCGACCCGCGGGCCGGCGGGCGATCGAGCCAGCGCAGGACCC
GCGGCTCGGCCCCCGGCCGCCGCCGGACCGAGAGTCTAGCCGCCGCCCCCAGCCCAGCCCGCCCGGCCGCAGGACCGCCGGGGCCTGGCC
GCCGGTCCGGCGTGCGCCAAGTTCAGCCGCCACCGGCACGGCCAGGCCAGCATGGTGGACCACTTACTTCCAGTGGACGAGAACTTCTCG
TCGCCAAAATGCCCAGTTGGGTATCTGGGTGATAGGCTGGTTGGCCGGCGGGCATATCACATGCTGCCCTCACCCGTCTCTGAAGATGAC
AGCGATGCCTCCAGCCCCTGCTCCTGTTCCAGTCCCGACTCTCAAGCCCTCTGCTCCTGCTATGGTGGAGGCCTGGGCACCGAGAGCCAG
GACAGCATCTTGGACTTCCTATTGTCCCAGGCCACGCTGGGCAGTGGCGGGGGCAGCGGCAGTAGCATTGGGGCCAGCAGTGGCCCCGTG
GCCTGGGGGCCCTGGCGAAGGGCAGCGGCCCCTGTGAAGGGGGAGCATTTCTGCTTGCCCGAGTTTCCTTTGGGTGATCCTGATGACGTC
CCACGGCCCTTCCAGCCTACCCTGGAGGAGATTGAAGAGTTTCTGGAGGAGAACATGGAGCCTGGAGTCAAGGAGGTCCCTGAGGGCAAC
AGCAAGGACTTGGATGCCTGCAGCCAGCTCTCAGCTGGGCCACACAAGAGCCACCTCCATCCTGGGTCCAGCGGGAGAGAGCGCTGTTCC
CCTCCACCAGGTGGTGCCAGTGCAGGAGGTGCCCAGGGCCCAGGTGGGGGCCCCACGCCTGATGGCCCCATCCCAGTGTTGCTGCAGATC
CAGCCCGTGCCTGTGAAGCAGGAATCGGGCACAGGGCCTGCCTCCCCTGGGCAAGCCCCAGAGAATGTCAAGGTTGCCCAGCTCCTGGTC
AACATCCAGGGGCAGACCTTCGCACTCGTGCCCCAGGTGGTACCCTCCTCCAACTTGAACCTGCCCTCCAAGTTTGTGCGCATTGCCCCT
GTGCCCATTGCCGCCAAGCCTGTTGGATCGGGACCCCTGGGGCCTGGCCCTGCCGGTCTCCTCATGGGCCAGAAGTTCCCCAAGAACCCA
GCCGCAGAACTCATCAAAATGCACAAATGTACTTTCCCTGGCTGCAGCAAGATGTACACCAAAAGCAGCCACCTCAAGGCCCACCTGCGC
CGGCACACGGGTGAGAAGCCCTTCGCCTGCACCTGGCCAGGCTGCGGCTGGAGGCCAACACTGGACAAATTGATGACCCCCAGGAGCAGC
ACAGAGTCATCAGCAGCAACCTGGCCCTCATCCAGGTGCAGGCCACTGTCGTGGGGCTCTTGGCTGCTGTGGCTGCGCTGCTGTTGGGCG
TGGTGTCTCGAGAGGAAGTGGATGTCGCCAAGGTGGAGTTGCTGTGTGCCAGCAGTGTCCTCACTGCCTTCCTTGCAGCCTTTGCCCTGG
GGGTGCTGATGGTCTGTATAGTGATTGGTGCTCGAAAGCTCGGGGTCAACCCAGACAACATTGCCACGCCCATTGCAGCCAGCCTGGGAG
ACCTCATCACACTGTCCATTCTGGCTTTGGTTAGCAGCTTCTTCTACAGACACAAAGATAGTCGGTATCTGACGCCGCTGGTCTGCCTCA
GCTTTGCGGCTCTGACCCCAGTGTGGGTCCTCATTGCCAAGCAGAGCCCACCCATCGTGAAGATCCTGAAGTTTGGCTGGTTCCCAATCA
TCCTGGCCATGGTCATCAGCAGTTTCGGAGGACTCATCTTGAGCAAAACCGTTTCTAAACAGCAGTACAAAGGCATGGCGATATTTACCC
CCGTCATATGTGGTGTTGGTGGCAATCTGGTGGCCATTCAGACCAGCCGAATCTCAACCTACCTGCACATGTGGAGTGCACCTGGCGTCC
TGCCCCTCCAGATGAAGAAATTCTGGCCCAACCCGTGTTCTACTTTCTGCACGTCAGAAATCAATTCCATGTCAGCTCGAGTCCTGCTCT
TGCTGGTGGTCCCAGGCCATCTGATTTTCTTCTACATCATCTACCTGGTGGAGGGTCAGTCAGTCATAAACAGCCAGACCTTTGTGGTGC
TCTACCTGCTGGCAGGCCTGATCCAGGTGACAATCCTGCTGTACCTCGCAGAAGTGATGGTTCGGCTGACTTGGCACCAGGCCCTGGATC
CTGACAACCACTGCATCCCCTACCTTACAGGGCTGGGGGACCTGCTCGGTACTGGCCTCCTGGCACTCTGCTTTTTCACTGACTGGCTAC
TGAAGAGCAAGGCAGAGCTGGGTGGCATCTCAGAACTGGCATCTGGACCTCCCTAACTGGGCCCCGCTGGTCCCATTTGCTCATTAGAAT
TTCCTCTCACATCAGTGGGATACAGAATTCAGTTTCTCCCTTGCCAGGTCCTTGGGATGGTTGACCCCTGCCTCTGCAGTAGCCTTTTGT

>42864_42864_5_KLF15-SLC41A3_KLF15_chr3_126070684_ENST00000296233_SLC41A3_chr3_125752521_ENST00000508835_length(amino acids)=503AA_BP=1
MNGHQIATNTTYDGGKYRHAFVLLFRNGFAQDESSETADDHGQDDWEPAKLQDLHDGWALLGNEDPHWGQSRKAEADQRRQIPTIFVSVE
EAANQSQNGQCDEVSQAGCNGRGNVVWVDPELSSTNHYTDHQHPQGKGCKEGSEDTAGTQQLHLGDIHFLSRHHAQQQRSHSSQEPHDSG
LHLDEGQVAADDSVLLLGVINLSSVGLQPQPGQVQAKGFSPVCRRRWALRWLLLVYILLQPGKVHLCILMSSAAGFLGNFWPMRRPAGPG
PRGPDPTGLAAMGTGAMRTNLEGRFKLEEGTTWGTSAKVCPWMLTRSWATLTFSGACPGEAGPVPDSCFTGTGWICSNTGMGPSGVGPPP
GPWAPPALAPPGGGEQRSLPLDPGWRWLLCGPAESWLQASKSLLLPSGTSLTPGSMFSSRNSSISSRVGWKGRGTSSGSPKGNSGKQKCS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for KLF15-SLC41A3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KLF15-SLC41A3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KLF15-SLC41A3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource