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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KLHL22-KIAA1549L (FusionGDB2 ID:42958)

Fusion Gene Summary for KLHL22-KIAA1549L

check button Fusion gene summary
Fusion gene informationFusion gene name: KLHL22-KIAA1549L
Fusion gene ID: 42958
HgeneTgene
Gene symbol

KLHL22

KIAA1549L

Gene ID

84861

25758

Gene namekelch like family member 22KIAA1549 like
SynonymsKELCHLC11orf41|C11orf69|G2
Cytomap

22q11.21

11p13

Type of geneprotein-codingprotein-coding
Descriptionkelch-like protein 22kelch-like 22UPF0606 protein KIAA1549LUPF0606 protein C11orf41uncharacterized protein C11orf69
Modification date2020031320200313
UniProtAcc.

Q6ZVL6

Ensembl transtripts involved in fusion geneENST00000328879, ENST00000440659, 
ENST00000470335, 		ENST00000265654, 
ENST00000321505, ENST00000389726, 
Fusion gene scores* DoF score10 X 9 X 6=54010 X 11 X 5=550
# samples 139
** MAII scorelog2(13/540*10)=-2.05444778402238
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/550*10)=-2.61143471208235
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KLHL22 [Title/Abstract] AND KIAA1549L [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKLHL22(20819145)-KIAA1549L(33677558), # samples:1
Anticipated loss of major functional domain due to fusion event.KLHL22-KIAA1549L seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKLHL22

GO:0006513

protein monoubiquitination

23455478


check buttonFusion gene breakpoints across KLHL22 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across KIAA1549L (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4HNSCTCGA-CV-6937-01AKLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+


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Fusion Gene ORF analysis for KLHL22-KIAA1549L

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000328879ENST00000265654KLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+
5CDS-intronENST00000440659ENST00000265654KLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+
Frame-shiftENST00000440659ENST00000321505KLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+
Frame-shiftENST00000440659ENST00000389726KLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+
In-frameENST00000328879ENST00000321505KLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+
In-frameENST00000328879ENST00000389726KLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+
intron-3CDSENST00000470335ENST00000321505KLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+
intron-3CDSENST00000470335ENST00000389726KLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+
intron-intronENST00000470335ENST00000265654KLHL22chr22

20819145

-KIAA1549Lchr11

33677558

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000328879KLHL22chr2220819145-ENST00000321505KIAA1549Lchr1133677558+789812691571482441
ENST00000328879KLHL22chr2220819145-ENST00000389726KIAA1549Lchr1133677558+789812691571482441

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000328879ENST00000321505KLHL22chr2220819145-KIAA1549Lchr1133677558+0.0025971460.99740285
ENST00000328879ENST00000389726KLHL22chr2220819145-KIAA1549Lchr1133677558+0.0025971460.99740285

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Fusion Genomic Features for KLHL22-KIAA1549L


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KLHL22chr2220819144-KIAA1549Lchr1133677557+0.0273338460.9726661
KLHL22chr2220819144-KIAA1549Lchr1133677557+0.0273338460.9726661

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for KLHL22-KIAA1549L


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:20819145/chr11:33677558)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.KIAA1549L

Q6ZVL6

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKLHL22chr22:20819145chr11:33677558ENST00000328879-4750_117370635.0DomainBTB
HgeneKLHL22chr22:20819145chr11:33677558ENST00000328879-47299_349370635.0RepeatNote=Kelch 1
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST00000265654011958_98601236.0Coiled coilOntology_term=ECO:0000255
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST000002656540111196_120001236.0Compositional biasNote=Poly-Ile
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST000002656540111638_164401236.0Compositional biasNote=Poly-Pro
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST0000026565401157_6201236.0Compositional biasNote=Poly-Pro
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST0000032150515201638_164416231850.0Compositional biasNote=Poly-Pro
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST000002656540111180_120001236.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKLHL22chr22:20819145chr11:33677558ENST00000328879-47350_399370635.0RepeatNote=Kelch 2
HgeneKLHL22chr22:20819145chr11:33677558ENST00000328879-47400_446370635.0RepeatNote=Kelch 3
HgeneKLHL22chr22:20819145chr11:33677558ENST00000328879-47448_493370635.0RepeatNote=Kelch 4
HgeneKLHL22chr22:20819145chr11:33677558ENST00000328879-47494_544370635.0RepeatNote=Kelch 5
HgeneKLHL22chr22:20819145chr11:33677558ENST00000328879-47545_593370635.0RepeatNote=Kelch 6
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST000003215051520958_98616231850.0Coiled coilOntology_term=ECO:0000255
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST0000032150515201196_120016231850.0Compositional biasNote=Poly-Ile
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST00000321505152057_6216231850.0Compositional biasNote=Poly-Pro
TgeneKIAA1549Lchr22:20819145chr11:33677558ENST0000032150515201180_120016231850.0TransmembraneHelical


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Fusion Gene Sequence for KLHL22-KIAA1549L


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>42958_42958_1_KLHL22-KIAA1549L_KLHL22_chr22_20819145_ENST00000328879_KIAA1549L_chr11_33677558_ENST00000321505_length(transcript)=7898nt_BP=1269nt
ACGTGACGGCCCAGGCCCCCGCCCCGCCGGCTCCTCTCGCCCAGCCTCCCGCCTCGCGCCTCCCGCCTCCCGCCTCCCGCCTCCCTCCAG
CTGCGAGTGCGGCCTCGGCTGGCGGCGGCACCAGGCCACAGTTGTAAGGGATCTTGTGGCTGTCAGGATGGCAGAGGAGCAGGAGTTCAC
CCAGCTCTGCAAGTTGCCTGCACAGCCCTCACACCCACACTGCGTGAACAACACCTACCGCAGCGCACAGCACTCCCAGGCTCTGCTCCG
AGGGCTGCTGGCTCTCCGGGACAGCGGAATCCTCTTCGATGTTGTGCTGGTGGTGGAGGGCAGACACATCGAGGCCCATCGCATCCTGCT
GGCTGCGTCCTGCGATTACTTCAGAGGAATGTTTGCTGGGGGATTGAAGGAGATGGAACAGGAAGAGGTCCTGATCCACGGTGTGTCCTA
CAATGCTATGTGCCAAATCCTACATTTCATATACACCTCCGAGCTGGAGCTCAGCCTGAGCAATGTACAAGAGACACTGGTGGCTGCCTG
CCAGCTTCAGATCCCAGAAATTATCCATTTCTGCTGTGATTTCCTCATGTCCTGGGTGGACGAAGAGAACATTCTCGATGTCTACCGGCT
GGCAGAGCTGTTTGACTTGAGCCGCCTGACTGAGCAACTGGACACCTATATCCTCAAAAACTTTGTGGCCTTCTCTCGGACTGACAAGTA
CCGCCAGCTTCCATTGGAGAAGGTCTACTCCCTCCTCAGCAGCAATCGCCTGGAGGTCTCCTGCGAGACCGAGGTATATGAGGGGGCCCT
TCTCTACCATTATAGCCTGGAGCAGGTGCAGGCTGACCAGATCTCGCTGCACGAGCCCCCAAAGCTCCTTGAGACAGTGCGGTTTCCGCT
GATGGAAGCTGAGGTCCTGCAGCGGCTGCATGACAAGCTGGACCCCAGCCCTTTGAGGGACACAGTGGCCAGCGCCCTCATGTACCACCG
GAACGAGAGCCTACAGCCCAGCCTGCAGAGCCCGCAAACGGAGCTGCGGTCGGACTTCCAGTGCGTTGTGGGCTTCGGGGGCATTCACTC
CACGCCGTCCACTGTCCTCAGCGACCAGGCCAAGTATCTAAACCCCTTACTGGGAGAGTGGAAGCACTTCACTGCCTCCCTGGCCCCCCG
CATGTCCAACCAGGGCATCGCGGTGCTCAACAACTTCGTATACTTGATTGGAGGGGACAACAATGTCCAAGGATTTCGAGCAGAGTCCCG
ATGCTGGAGGCTTACAGGTTTTCCCAGCTTCCTGAGATGGTCATGGGCTCACCGCCTCCACCCGTACCTCCCCGGACTGGTCCTGTGGCT
GTCGCTTCTCTCAGGCGATCCACCTCAGACATCGGCAGCAAGACCAGAATGGCCGAGTCTACAGGGCCCGAGCCGGCCCAGCTGCACGAC
AGCGCCTCCTTCACGCAGATGTCCAGAGGCCCTGTGTCCGTGACGCAGTTGGATCAGTCGGCTTTAAATTACTCAGGTAATACGGTGCCA
GCAGTGTTCGCCATCCCAGCTGCCAACAGACCTGGCTTCACCGGCTACTTCATCCCAACGCCTCCCTCATCCTATAGGAACCAGGCCTGG
ATGTCCTATGCAGGAGAGAATGAGCTCCCGAGCCAGTGGGCAGATTCGGTGCCCCTCCCAGGGTACATCGAGGCCTACCCCCGATCACGG
TACCCCCAGAGCTCTCCCTCCAGGCTTCCTCGTCAGTACAGCCAGCCAGCCAACCTGCACCCCAGCCTGGAGCAGGCCCCGGCGCCCTCC
ACAGCGGCCTCGCAGCAGAGCCTGGCAGAAAACGACCCGTCTGACGCTCCCCTGACCAACATCTCCACTGCGGCCCTTGTGAAGGCCATC
CGGGAGGAGGTGGCCAAGCTGGCCAAAAAACAGACAGACATGTTTGAGTTCCAGGTCTAACGCCTTAGCCCCGTGGGACTCTGGACTTCC
AAACTCTGAGGACTCAGCCTTTGGGTTTCCCATGCCTACGTGTTAGGACTTGAGACATAGCAATGGGTGAGTCTTTCTCACCCTCCATTT
CTGAAAAGGTGAACTATGGGGCTTCTGGGAACAGGAAACTCTTGAACGACTAGATTCTTGGCTCATCCAACTGATTGTGGGTCAAGTCCC
TGGCTTGGGGCCTTATGTTTGATACTCTCTCATGTCAAATGTTTGAACTTTGGGCATGTGCCCTATGGAAGCTTAGTCACAAGAGGCACT
AGCTAATCTACAGATTCCTATCCAATGCCACATTTTAATAAATCACCGGAAGCGGGAGAATGTAGCTCTTATCTTCGGTGACCTCTGCAT
GTTAACTCTGTTTCTGTGTTAAAGGCAATGCAGGAGTGTGGATTAAGCACCAGACTGTATTCTCATTCAACCATGACCGTGCGCATTAAA
ATCAGTTTGTAAGGGAGACACTGACTCCAGCCAAGAAACCTGAGCCCCTTTTTTTTAGGTTCATATTCAAAGTCAAATGAACTGGATGAA
AGTCAGTACCAATGGCTGTGCCTATAAATAGACCTGATTCTTTGTTTCCCTCGTCAATTAAACAAAGGCCAAGAAAGAGAGAAGATGAGA
GGGAATGGTGGATTTGCGTTGACAGATTTTTTAAAAGGTGTTGCCATTTTGGAAATAAAAGTCCCCTACAAGTTAGGATCTAACTGAAAG
AGAATCGGTGCTAAGAGCTTTTAGGATCCTACAAAAGAAACACAGTTATTTGTGAAGGTTTTTCTTTGCCTTGTTTTGAAGGTGGCCTGA
GAATGGAGCTTCTCTTTTTCTTGGGATAATAGATACATCAACTTTTACAAGAAAATCTCTGTCTCTTCAACAATGATGTCCAGTGTGTGC
TGCTGAGTGGTACAAAAGGAAATAGTACTTGATTCCTGTTAGAAACAGGAGTGGTAGAACCACAGTCTTCCCAGGCCGCAGCCTCTGTTT
ATAGAAGCTTCTGAATGTAGAAAAGCTGTTGAATTTCATTTAAATGTAAATAACCTTTTAAAAAGCGTATGGAGTTAGCCAGTTCCCCCT
AGTTAATGGACATAGGAAGACATTTGCTGAAATGGTAGGGTGGCCACTTTGTGACCATGATGTTGCAAGTTGCCCTCCCTGGCATGGTGA
GTTGGCTTCCAGAGCTGTGGGTAGAGGACATCGCCTCACGGCACTGAGGCACCAGCCGCTGCCTACCCATCAATGCAAGCAAAACAGCTA
CTGACTTTGTGTAGCAGGGAGATTGGGGACTCTGGTTCCCTCGCCAAGTGTGGCAGCCTGTGCAGTGTTGGGGGCTTACTTGGTATCTGT
TGGAGAATGAGGTCCTGTCCTGCTTTCACCCATGACCCATCTAGCTTCAGCTGTATCCATTTTCTTCTGAGCCCATCTTCCATTGTCCTC
AACGAGTTTCTTTGGTCTTTACTGAAAGAAGATAGTAGAAATTTAAAAGTTGAGAGAAGACTAGAAATGGAACTGATTAGAAGGGGAGGT
TCAAACTGTCAATGCACAGACTTTTCAAAGAAGTTGTTTATATTTTCCAATGGCAAACTGCCCTTTCTGGAATGTTCAGAGATGATGTGT
CATGGAACCTTCAAACAAGTCTCTTGTTCGGATGATAATAGGTAGTGTCCTTTTAGTATGCTGGTTGATCTTTCATAGTGTTAGTGTTTT
GTTACTTAAAAAGGAAATCAGCTATAAATAAAATGTATTTTTGTAATTCCCGTGTGTATATATGGTATATTTCTATCAATGGCCAGTTGT
TGTAGTCCAAAACCTAAATCAGTTTGCAAAACACTGTGGACAGTGCGAGATTTTATTGACAGGTTAACACAATGCCTACGTCTATCCACA
TAGGCATTCAATGCACTTGAATGAACAAAGAGCCAAAGAAACTCAGCCTGTTCATGCAAATGGTATGAGTCTGATAAAATCAGCTACATT
GTCCTGCTTTATCAATAATAATATTTCATTAGTGCAATGATATCAACCAGTACTTTGTCTACTTGGTAAATGCCTGGAAATACTGTATGT
GAAAATGATGTTTCAAGATCTTACTGTAATTGAAGTATACGTAAATGTTTCAGAAGACAGTGTCTGAAATTTGGCTGTTTCAATGACTTA
CAGAGACTGAGTCTACAGTTTGCAGAGCTATGGCTCCAGAGTGCTAAGAGGGTGGAGTCACAAATCACTGTGGTCTTTACAGAGCCCCAG
GAAATACTGAGTGAGTCAACTGAGACGACTAAAAAGATAGCATGCTAAATCAGATACTGTCTTAAACTAGACACCATGGGTTCAAGAATA
GTATTAATAGATGAGAGGAAAACCTTAAGTTGGAAAGAAATCAGTCTGTTCATGTTATCCCACTCATGGGGAGACAGAGCCACTCTGGTC
AGATTTTCTGTGAGTGAGATGTGGTCCCTTCCCTGAAGAATCTCCTAACCTCATAGAGGTGAGAGAGATGACTGGACAGCTGACTCTAAG
AGATGGTCAAAAGTGCCTCAAGGAATTGAAATAAGGTTCCCAGAGAGCCCTGAGGAGGCAGCAATGAACAAACACCCTGTTCATCAGAAC
CCTCTAGATAGTCACAGAAGCCACAAAAGGACCTTGGTTGACCTTGGAGGAGGAAGCAGAAGTACCACGAAGTGGAGTGACTGGCCCAGT
GATTCAGTCCCAACCTCCTGGTTCACGAACCTGCTTGCTTTCCATCTCGCCATGTGGCCTGCAGGCTTGTCAGTAACACATTTCTTTAGC
TGTGCCTAGAGGTTTAAAAAAAAGATAAGGGTCATATGAAGAACTCCATAATGTTCTTGCCAAGAAAAAAGATGATTGAGTATATAACGA
ACTTCAGATACAGTGTATAGAGGATGATGCATTTGTGGCATAATAAATAGTTTTCAGTGCTGGTTTTGATATGAGTTTTCTGCATTCATG
AAAAAGAAATGCATTTTGGCTTTTTCCAGAAAGAGTACCATCAAGGAAACGGAGACCTCAACTGCTGTTCTAGACTGTGGGGGTGCATTC
CTGTCTCAGCACCAAGGATCCCAACAGGCAGGCAGGGAGGCCCTTGACTTTGTGTCACTGTGAGGCAGCAGAGTCCATGCTCTGCATCAG
GGGAGGTGCAGTAAAGGTCCATTGTGTGGCTTGAGACCTATGATCTGAGGCTTGTGCATAATAAGATGGCAGCTGTTACCTACAGAGCAA
GGAGTTTCCTCTTTCAGGGTAGATTATGTAAGAATCAATTCCCTGGTCCCAGGAGAAGTTTTATTGTGAGTTTGTTAATTTAAGAACTCA
CTCAGCAGAAGGACATGTAATGTCTGAGTAATCTTGATGGAAGAAAGGAAATAGATCTGTGATTAAAACACACACACACACACACACACA
CACACACACACACCCTACTTCGGAGAGAGAATGTAGAATGGAGGAGGTGAGGAATTTAACTAATAGAGATGCTTTTTCTAACAGGCAGAA
ATTAGAGAAATGGATCAAAAGATTTAAACATTGATTACATATAAACGAGTTTCCTTTTTTTCTACATAGCACACAGGTGCTCAACATTTA
ATGAATAATATAACAGATACTGTCTTAAAAGTTTAAAAACAGGATTTGTACTTAATCCTAAATTCCTCTTATCACACACCAGAAAATAAT
TTGGATTTTATTTACAAACTACATCCAAATACTCTTAAGGAAAGAGTGTCATTTAGCTTGGAGTAGGGACTGACTGGGGTCTAAGTGTTG
GAAATTAAATTCTGCCATTCAGTCCAACCTCAAAGGTGTTCCAGGCAAGGAGTTTTGCAAGGACTAGAAACCCTTTCACACTTGAAGTGC
AGGTGTTGGCTGAAAGAATAGAGGGACATTTCACAAACACAGAACACGGCTCCCCTACAGGAAAGGGATGGAGACAGCTACCTTTGCTCT
TGCTCTCACATTCTCTGTCCTCATGGACTTTCTTCTCTGTTTCCCTCTGCCTATCTATCTGCCTGGTTCTCTTGCTTCTCCTGGCCAACC
AGCTTTCTCATTAGTGCATATGTAGCTGAAAAATCCACCCCTCAAGAACCCACTCCACACAACCTTTCCTTTTCAGTACCCACCACGCTC
TGACTAGCATCTCTGTGATGCCTAAGGCAAATTTTTGAGGATCTGATTGGTTTAGTTCATCTGCCTATGGGTGAGCCACCCTGGGGTCAG
GTGCCTGTCCAATCACCTGTTACCAAGGAGGCAGGGCCGTGTCATTTAAGCATGGCCCCATGGACTGACCCTTTCAGCAGGGACTTTTAT
TGGGGGCTGGTACCCAGAAGAAGGAGCATGAGTGGGCAAGACCTTCAAAAAGAACCTACTACACACTGGAACTGACTAGTACTCCTGGGA
TGCCATGCCACGCAGCAGCCAGCACTCGGAGAGCAGTCCCCTGGATACTACCACACAGAGAAAAGGGGCATCTTCACTTGCACATCAGGT
GAGGGTGCACACACTTGAAACTCTGCTAGACTGGCCAGAGCTGCCCCAGCCACTTCTCACCCCACCACCAGTTATTGATACAGCCGCTGG
GTCTAGGAAGCGATTTCTGAACAAGGCCCAGTTAGCACAATGTCTTGCTCAGCAGACAATAAATACTTGTAAATTGAATTGCATGATCTT
AGCTCAGGTGCTACTAATGTGGCTCACGGCCACACACTTGCATGGATAAGAAAACCAATGAGCCCCTCAACAGAGTCTTTTGAAACAAAA
TTGGTTTCAAGTGAAACTTACATTATTTTTTGGCTGTGACCTTCTGAATATAATAACTTAGTGTCCTGAGAATTGAAAGGCCTCTTGATT
TCTTAGGTGAACTGTTACAGAATCCTAGCCTGTGGTAAATGCTAAAATGTAAGGTGTTTCTGAGAAGGAATATTTAGGAAATATAATTGT
GCCACACACACATTACTTTAGAAGATATGCAGTTGCTCTGATTCTGCAGGTTTAAAAAAAATGGGAAGTTTGTGATATGGCAGAATCTGT
CTCCATTGGTCAAACCATACTTCAGTGAGAGCCATTATAAGTGAAATCTAAAAATTGATCGTTTTCATTCTCTGACTTTGGTCAGACTTT
TGCAAATTATGGAGAGAGGCCATCAACATATTTTACATAAATTACTGTGGCCCCATCTTATTTCTCCTCATTTCTTCCTTATGTTTAAAC
ACGCCCCCATCTCACACACAAACTGAGAAAAGATTTGTATCAAACAGAATCAGAGGCATATGAATGGACTGGAAATTGTGAAAAAGGTAT
AAATATCCTAGACCTTGATCAACTCACTTTAAACTGGTCTCTGATTCCTCATCTGTCAAATGAGTATAAGACCCTCTGTACTTCCCATGG
TGATTTTGAGGAGCACATGCATAATGTATCTGAAAATGGCTTGACAAGCACTTGAAGCCATTCTTACTAAATTATTAGTTTTGTAATTCG
GTTTTATCCAGGAAAATATTTTAGCTCCTCCTATCTGCTGAATTAATTTATACAGTCACATGTTCCATGACACCATGTTTTGCCAAGGAA
AAATAAAGAAATTCCTAAATTTGAAATTGCCCACAAGATCTAGCCTCATCTGGAGTTGCTGTTATTGTCCTTGTTGTCTATGATTTGGAG
GATATGTAAGTACTTGTACATGTGCTTTAACTCTGGGTGAAAAACCCCAACCGGTGAGTCTTTAAAACCATATTAGACACATTGGGCAAA
GTACTGAGCAGAAGCTTTGAATGTAGCTGTTGTTATTTTAATGCTTCGCTTTCTAATGAACTTTGTACGTCCTTAGCCTCTGCCGGGAAC

>42958_42958_1_KLHL22-KIAA1549L_KLHL22_chr22_20819145_ENST00000328879_KIAA1549L_chr11_33677558_ENST00000321505_length(amino acids)=441AA_BP=370
MAEEQEFTQLCKLPAQPSHPHCVNNTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEMEQEE
VLIHGVSYNAMCQILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLMSWVDEENILDVYRLAELFDLSRLTEQLDTYILKNFV
AFSRTDKYRQLPLEKVYSLLSSNRLEVSCETEVYEGALLYHYSLEQVQADQISLHEPPKLLETVRFPLMEAEVLQRLHDKLDPSPLRDTV
ASALMYHRNESLQPSLQSPQTELRSDFQCVVGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTASLAPRMSNQGIAVLNNFVYLIGGDNNV

--------------------------------------------------------------
>42958_42958_2_KLHL22-KIAA1549L_KLHL22_chr22_20819145_ENST00000328879_KIAA1549L_chr11_33677558_ENST00000389726_length(transcript)=7898nt_BP=1269nt
ACGTGACGGCCCAGGCCCCCGCCCCGCCGGCTCCTCTCGCCCAGCCTCCCGCCTCGCGCCTCCCGCCTCCCGCCTCCCGCCTCCCTCCAG
CTGCGAGTGCGGCCTCGGCTGGCGGCGGCACCAGGCCACAGTTGTAAGGGATCTTGTGGCTGTCAGGATGGCAGAGGAGCAGGAGTTCAC
CCAGCTCTGCAAGTTGCCTGCACAGCCCTCACACCCACACTGCGTGAACAACACCTACCGCAGCGCACAGCACTCCCAGGCTCTGCTCCG
AGGGCTGCTGGCTCTCCGGGACAGCGGAATCCTCTTCGATGTTGTGCTGGTGGTGGAGGGCAGACACATCGAGGCCCATCGCATCCTGCT
GGCTGCGTCCTGCGATTACTTCAGAGGAATGTTTGCTGGGGGATTGAAGGAGATGGAACAGGAAGAGGTCCTGATCCACGGTGTGTCCTA
CAATGCTATGTGCCAAATCCTACATTTCATATACACCTCCGAGCTGGAGCTCAGCCTGAGCAATGTACAAGAGACACTGGTGGCTGCCTG
CCAGCTTCAGATCCCAGAAATTATCCATTTCTGCTGTGATTTCCTCATGTCCTGGGTGGACGAAGAGAACATTCTCGATGTCTACCGGCT
GGCAGAGCTGTTTGACTTGAGCCGCCTGACTGAGCAACTGGACACCTATATCCTCAAAAACTTTGTGGCCTTCTCTCGGACTGACAAGTA
CCGCCAGCTTCCATTGGAGAAGGTCTACTCCCTCCTCAGCAGCAATCGCCTGGAGGTCTCCTGCGAGACCGAGGTATATGAGGGGGCCCT
TCTCTACCATTATAGCCTGGAGCAGGTGCAGGCTGACCAGATCTCGCTGCACGAGCCCCCAAAGCTCCTTGAGACAGTGCGGTTTCCGCT
GATGGAAGCTGAGGTCCTGCAGCGGCTGCATGACAAGCTGGACCCCAGCCCTTTGAGGGACACAGTGGCCAGCGCCCTCATGTACCACCG
GAACGAGAGCCTACAGCCCAGCCTGCAGAGCCCGCAAACGGAGCTGCGGTCGGACTTCCAGTGCGTTGTGGGCTTCGGGGGCATTCACTC
CACGCCGTCCACTGTCCTCAGCGACCAGGCCAAGTATCTAAACCCCTTACTGGGAGAGTGGAAGCACTTCACTGCCTCCCTGGCCCCCCG
CATGTCCAACCAGGGCATCGCGGTGCTCAACAACTTCGTATACTTGATTGGAGGGGACAACAATGTCCAAGGATTTCGAGCAGAGTCCCG
ATGCTGGAGGCTTACAGGTTTTCCCAGCTTCCTGAGATGGTCATGGGCTCACCGCCTCCACCCGTACCTCCCCGGACTGGTCCTGTGGCT
GTCGCTTCTCTCAGGCGATCCACCTCAGACATCGGCAGCAAGACCAGAATGGCCGAGTCTACAGGGCCCGAGCCGGCCCAGCTGCACGAC
AGCGCCTCCTTCACGCAGATGTCCAGAGGCCCTGTGTCCGTGACGCAGTTGGATCAGTCGGCTTTAAATTACTCAGGTAATACGGTGCCA
GCAGTGTTCGCCATCCCAGCTGCCAACAGACCTGGCTTCACCGGCTACTTCATCCCAACGCCTCCCTCATCCTATAGGAACCAGGCCTGG
ATGTCCTATGCAGGAGAGAATGAGCTCCCGAGCCAGTGGGCAGATTCGGTGCCCCTCCCAGGGTACATCGAGGCCTACCCCCGATCACGG
TACCCCCAGAGCTCTCCCTCCAGGCTTCCTCGTCAGTACAGCCAGCCAGCCAACCTGCACCCCAGCCTGGAGCAGGCCCCGGCGCCCTCC
ACAGCGGCCTCGCAGCAGAGCCTGGCAGAAAACGACCCGTCTGACGCTCCCCTGACCAACATCTCCACTGCGGCCCTTGTGAAGGCCATC
CGGGAGGAGGTGGCCAAGCTGGCCAAAAAACAGACAGACATGTTTGAGTTCCAGGTCTAACGCCTTAGCCCCGTGGGACTCTGGACTTCC
AAACTCTGAGGACTCAGCCTTTGGGTTTCCCATGCCTACGTGTTAGGACTTGAGACATAGCAATGGGTGAGTCTTTCTCACCCTCCATTT
CTGAAAAGGTGAACTATGGGGCTTCTGGGAACAGGAAACTCTTGAACGACTAGATTCTTGGCTCATCCAACTGATTGTGGGTCAAGTCCC
TGGCTTGGGGCCTTATGTTTGATACTCTCTCATGTCAAATGTTTGAACTTTGGGCATGTGCCCTATGGAAGCTTAGTCACAAGAGGCACT
AGCTAATCTACAGATTCCTATCCAATGCCACATTTTAATAAATCACCGGAAGCGGGAGAATGTAGCTCTTATCTTCGGTGACCTCTGCAT
GTTAACTCTGTTTCTGTGTTAAAGGCAATGCAGGAGTGTGGATTAAGCACCAGACTGTATTCTCATTCAACCATGACCGTGCGCATTAAA
ATCAGTTTGTAAGGGAGACACTGACTCCAGCCAAGAAACCTGAGCCCCTTTTTTTTAGGTTCATATTCAAAGTCAAATGAACTGGATGAA
AGTCAGTACCAATGGCTGTGCCTATAAATAGACCTGATTCTTTGTTTCCCTCGTCAATTAAACAAAGGCCAAGAAAGAGAGAAGATGAGA
GGGAATGGTGGATTTGCGTTGACAGATTTTTTAAAAGGTGTTGCCATTTTGGAAATAAAAGTCCCCTACAAGTTAGGATCTAACTGAAAG
AGAATCGGTGCTAAGAGCTTTTAGGATCCTACAAAAGAAACACAGTTATTTGTGAAGGTTTTTCTTTGCCTTGTTTTGAAGGTGGCCTGA
GAATGGAGCTTCTCTTTTTCTTGGGATAATAGATACATCAACTTTTACAAGAAAATCTCTGTCTCTTCAACAATGATGTCCAGTGTGTGC
TGCTGAGTGGTACAAAAGGAAATAGTACTTGATTCCTGTTAGAAACAGGAGTGGTAGAACCACAGTCTTCCCAGGCCGCAGCCTCTGTTT
ATAGAAGCTTCTGAATGTAGAAAAGCTGTTGAATTTCATTTAAATGTAAATAACCTTTTAAAAAGCGTATGGAGTTAGCCAGTTCCCCCT
AGTTAATGGACATAGGAAGACATTTGCTGAAATGGTAGGGTGGCCACTTTGTGACCATGATGTTGCAAGTTGCCCTCCCTGGCATGGTGA
GTTGGCTTCCAGAGCTGTGGGTAGAGGACATCGCCTCACGGCACTGAGGCACCAGCCGCTGCCTACCCATCAATGCAAGCAAAACAGCTA
CTGACTTTGTGTAGCAGGGAGATTGGGGACTCTGGTTCCCTCGCCAAGTGTGGCAGCCTGTGCAGTGTTGGGGGCTTACTTGGTATCTGT
TGGAGAATGAGGTCCTGTCCTGCTTTCACCCATGACCCATCTAGCTTCAGCTGTATCCATTTTCTTCTGAGCCCATCTTCCATTGTCCTC
AACGAGTTTCTTTGGTCTTTACTGAAAGAAGATAGTAGAAATTTAAAAGTTGAGAGAAGACTAGAAATGGAACTGATTAGAAGGGGAGGT
TCAAACTGTCAATGCACAGACTTTTCAAAGAAGTTGTTTATATTTTCCAATGGCAAACTGCCCTTTCTGGAATGTTCAGAGATGATGTGT
CATGGAACCTTCAAACAAGTCTCTTGTTCGGATGATAATAGGTAGTGTCCTTTTAGTATGCTGGTTGATCTTTCATAGTGTTAGTGTTTT
GTTACTTAAAAAGGAAATCAGCTATAAATAAAATGTATTTTTGTAATTCCCGTGTGTATATATGGTATATTTCTATCAATGGCCAGTTGT
TGTAGTCCAAAACCTAAATCAGTTTGCAAAACACTGTGGACAGTGCGAGATTTTATTGACAGGTTAACACAATGCCTACGTCTATCCACA
TAGGCATTCAATGCACTTGAATGAACAAAGAGCCAAAGAAACTCAGCCTGTTCATGCAAATGGTATGAGTCTGATAAAATCAGCTACATT
GTCCTGCTTTATCAATAATAATATTTCATTAGTGCAATGATATCAACCAGTACTTTGTCTACTTGGTAAATGCCTGGAAATACTGTATGT
GAAAATGATGTTTCAAGATCTTACTGTAATTGAAGTATACGTAAATGTTTCAGAAGACAGTGTCTGAAATTTGGCTGTTTCAATGACTTA
CAGAGACTGAGTCTACAGTTTGCAGAGCTATGGCTCCAGAGTGCTAAGAGGGTGGAGTCACAAATCACTGTGGTCTTTACAGAGCCCCAG
GAAATACTGAGTGAGTCAACTGAGACGACTAAAAAGATAGCATGCTAAATCAGATACTGTCTTAAACTAGACACCATGGGTTCAAGAATA
GTATTAATAGATGAGAGGAAAACCTTAAGTTGGAAAGAAATCAGTCTGTTCATGTTATCCCACTCATGGGGAGACAGAGCCACTCTGGTC
AGATTTTCTGTGAGTGAGATGTGGTCCCTTCCCTGAAGAATCTCCTAACCTCATAGAGGTGAGAGAGATGACTGGACAGCTGACTCTAAG
AGATGGTCAAAAGTGCCTCAAGGAATTGAAATAAGGTTCCCAGAGAGCCCTGAGGAGGCAGCAATGAACAAACACCCTGTTCATCAGAAC
CCTCTAGATAGTCACAGAAGCCACAAAAGGACCTTGGTTGACCTTGGAGGAGGAAGCAGAAGTACCACGAAGTGGAGTGACTGGCCCAGT
GATTCAGTCCCAACCTCCTGGTTCACGAACCTGCTTGCTTTCCATCTCGCCATGTGGCCTGCAGGCTTGTCAGTAACACATTTCTTTAGC
TGTGCCTAGAGGTTTAAAAAAAAGATAAGGGTCATATGAAGAACTCCATAATGTTCTTGCCAAGAAAAAAGATGATTGAGTATATAACGA
ACTTCAGATACAGTGTATAGAGGATGATGCATTTGTGGCATAATAAATAGTTTTCAGTGCTGGTTTTGATATGAGTTTTCTGCATTCATG
AAAAAGAAATGCATTTTGGCTTTTTCCAGAAAGAGTACCATCAAGGAAACGGAGACCTCAACTGCTGTTCTAGACTGTGGGGGTGCATTC
CTGTCTCAGCACCAAGGATCCCAACAGGCAGGCAGGGAGGCCCTTGACTTTGTGTCACTGTGAGGCAGCAGAGTCCATGCTCTGCATCAG
GGGAGGTGCAGTAAAGGTCCATTGTGTGGCTTGAGACCTATGATCTGAGGCTTGTGCATAATAAGATGGCAGCTGTTACCTACAGAGCAA
GGAGTTTCCTCTTTCAGGGTAGATTATGTAAGAATCAATTCCCTGGTCCCAGGAGAAGTTTTATTGTGAGTTTGTTAATTTAAGAACTCA
CTCAGCAGAAGGACATGTAATGTCTGAGTAATCTTGATGGAAGAAAGGAAATAGATCTGTGATTAAAACACACACACACACACACACACA
CACACACACACACCCTACTTCGGAGAGAGAATGTAGAATGGAGGAGGTGAGGAATTTAACTAATAGAGATGCTTTTTCTAACAGGCAGAA
ATTAGAGAAATGGATCAAAAGATTTAAACATTGATTACATATAAACGAGTTTCCTTTTTTTCTACATAGCACACAGGTGCTCAACATTTA
ATGAATAATATAACAGATACTGTCTTAAAAGTTTAAAAACAGGATTTGTACTTAATCCTAAATTCCTCTTATCACACACCAGAAAATAAT
TTGGATTTTATTTACAAACTACATCCAAATACTCTTAAGGAAAGAGTGTCATTTAGCTTGGAGTAGGGACTGACTGGGGTCTAAGTGTTG
GAAATTAAATTCTGCCATTCAGTCCAACCTCAAAGGTGTTCCAGGCAAGGAGTTTTGCAAGGACTAGAAACCCTTTCACACTTGAAGTGC
AGGTGTTGGCTGAAAGAATAGAGGGACATTTCACAAACACAGAACACGGCTCCCCTACAGGAAAGGGATGGAGACAGCTACCTTTGCTCT
TGCTCTCACATTCTCTGTCCTCATGGACTTTCTTCTCTGTTTCCCTCTGCCTATCTATCTGCCTGGTTCTCTTGCTTCTCCTGGCCAACC
AGCTTTCTCATTAGTGCATATGTAGCTGAAAAATCCACCCCTCAAGAACCCACTCCACACAACCTTTCCTTTTCAGTACCCACCACGCTC
TGACTAGCATCTCTGTGATGCCTAAGGCAAATTTTTGAGGATCTGATTGGTTTAGTTCATCTGCCTATGGGTGAGCCACCCTGGGGTCAG
GTGCCTGTCCAATCACCTGTTACCAAGGAGGCAGGGCCGTGTCATTTAAGCATGGCCCCATGGACTGACCCTTTCAGCAGGGACTTTTAT
TGGGGGCTGGTACCCAGAAGAAGGAGCATGAGTGGGCAAGACCTTCAAAAAGAACCTACTACACACTGGAACTGACTAGTACTCCTGGGA
TGCCATGCCACGCAGCAGCCAGCACTCGGAGAGCAGTCCCCTGGATACTACCACACAGAGAAAAGGGGCATCTTCACTTGCACATCAGGT
GAGGGTGCACACACTTGAAACTCTGCTAGACTGGCCAGAGCTGCCCCAGCCACTTCTCACCCCACCACCAGTTATTGATACAGCCGCTGG
GTCTAGGAAGCGATTTCTGAACAAGGCCCAGTTAGCACAATGTCTTGCTCAGCAGACAATAAATACTTGTAAATTGAATTGCATGATCTT
AGCTCAGGTGCTACTAATGTGGCTCACGGCCACACACTTGCATGGATAAGAAAACCAATGAGCCCCTCAACAGAGTCTTTTGAAACAAAA
TTGGTTTCAAGTGAAACTTACATTATTTTTTGGCTGTGACCTTCTGAATATAATAACTTAGTGTCCTGAGAATTGAAAGGCCTCTTGATT
TCTTAGGTGAACTGTTACAGAATCCTAGCCTGTGGTAAATGCTAAAATGTAAGGTGTTTCTGAGAAGGAATATTTAGGAAATATAATTGT
GCCACACACACATTACTTTAGAAGATATGCAGTTGCTCTGATTCTGCAGGTTTAAAAAAAATGGGAAGTTTGTGATATGGCAGAATCTGT
CTCCATTGGTCAAACCATACTTCAGTGAGAGCCATTATAAGTGAAATCTAAAAATTGATCGTTTTCATTCTCTGACTTTGGTCAGACTTT
TGCAAATTATGGAGAGAGGCCATCAACATATTTTACATAAATTACTGTGGCCCCATCTTATTTCTCCTCATTTCTTCCTTATGTTTAAAC
ACGCCCCCATCTCACACACAAACTGAGAAAAGATTTGTATCAAACAGAATCAGAGGCATATGAATGGACTGGAAATTGTGAAAAAGGTAT
AAATATCCTAGACCTTGATCAACTCACTTTAAACTGGTCTCTGATTCCTCATCTGTCAAATGAGTATAAGACCCTCTGTACTTCCCATGG
TGATTTTGAGGAGCACATGCATAATGTATCTGAAAATGGCTTGACAAGCACTTGAAGCCATTCTTACTAAATTATTAGTTTTGTAATTCG
GTTTTATCCAGGAAAATATTTTAGCTCCTCCTATCTGCTGAATTAATTTATACAGTCACATGTTCCATGACACCATGTTTTGCCAAGGAA
AAATAAAGAAATTCCTAAATTTGAAATTGCCCACAAGATCTAGCCTCATCTGGAGTTGCTGTTATTGTCCTTGTTGTCTATGATTTGGAG
GATATGTAAGTACTTGTACATGTGCTTTAACTCTGGGTGAAAAACCCCAACCGGTGAGTCTTTAAAACCATATTAGACACATTGGGCAAA
GTACTGAGCAGAAGCTTTGAATGTAGCTGTTGTTATTTTAATGCTTCGCTTTCTAATGAACTTTGTACGTCCTTAGCCTCTGCCGGGAAC

>42958_42958_2_KLHL22-KIAA1549L_KLHL22_chr22_20819145_ENST00000328879_KIAA1549L_chr11_33677558_ENST00000389726_length(amino acids)=441AA_BP=370
MAEEQEFTQLCKLPAQPSHPHCVNNTYRSAQHSQALLRGLLALRDSGILFDVVLVVEGRHIEAHRILLAASCDYFRGMFAGGLKEMEQEE
VLIHGVSYNAMCQILHFIYTSELELSLSNVQETLVAACQLQIPEIIHFCCDFLMSWVDEENILDVYRLAELFDLSRLTEQLDTYILKNFV
AFSRTDKYRQLPLEKVYSLLSSNRLEVSCETEVYEGALLYHYSLEQVQADQISLHEPPKLLETVRFPLMEAEVLQRLHDKLDPSPLRDTV
ASALMYHRNESLQPSLQSPQTELRSDFQCVVGFGGIHSTPSTVLSDQAKYLNPLLGEWKHFTASLAPRMSNQGIAVLNNFVYLIGGDNNV

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Fusion Gene PPI Analysis for KLHL22-KIAA1549L


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KLHL22-KIAA1549L


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KLHL22-KIAA1549L


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource