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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANAPC5-SRRM2 (FusionGDB2 ID:4302)

Fusion Gene Summary for ANAPC5-SRRM2

check button Fusion gene summary
Fusion gene informationFusion gene name: ANAPC5-SRRM2
Fusion gene ID: 4302
HgeneTgene
Gene symbol

ANAPC5

SRRM2

Gene ID

51433

23524

Gene nameanaphase promoting complex subunit 5serine/arginine repetitive matrix 2
SynonymsAPC5300-KD|CWF21|Cwc21|HSPC075|SRL300|SRm300
Cytomap

12q24.31

16p13.3

Type of geneprotein-codingprotein-coding
Descriptionanaphase-promoting complex subunit 5cyclosome subunit 5serine/arginine repetitive matrix protein 2300 kDa nuclear matrix antigenRNA binding proteinSR-related nuclear matrix protein of 300 kDaser/Arg-related nuclear matrix protein of 300 kDaserine/arginine-rich splicing factor-related nuclear matrix prote
Modification date2020031320200313
UniProtAcc

Q9UJX4

.
Ensembl transtripts involved in fusion geneENST00000261819, ENST00000344395, 
ENST00000441917, ENST00000535482, 
ENST00000541887, ENST00000544314, 
ENST00000536366, 		ENST00000574593, 
ENST00000301740, 
Fusion gene scores* DoF score9 X 11 X 6=59420 X 27 X 9=4860
# samples 1128
** MAII scorelog2(11/594*10)=-2.43295940727611
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(28/4860*10)=-4.11745758154818
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANAPC5 [Title/Abstract] AND SRRM2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANAPC5(121766118)-SRRM2(2808985), # samples:1
Anticipated loss of major functional domain due to fusion event.ANAPC5-SRRM2 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ANAPC5-SRRM2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANAPC5

GO:0070979

protein K11-linked ubiquitination

18485873

TgeneSRRM2

GO:0000398

mRNA splicing, via spliceosome

28076346


check buttonFusion gene breakpoints across ANAPC5 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SRRM2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4Non-Cancer269NANAPC5chr12

121766118

-SRRM2chr16

2808985

+


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Fusion Gene ORF analysis for ANAPC5-SRRM2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000261819ENST00000574593ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
5CDS-intronENST00000344395ENST00000574593ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
5CDS-intronENST00000441917ENST00000574593ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
5CDS-intronENST00000535482ENST00000574593ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
5CDS-intronENST00000541887ENST00000574593ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
5UTR-3CDSENST00000544314ENST00000301740ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
5UTR-intronENST00000544314ENST00000574593ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
Frame-shiftENST00000441917ENST00000301740ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
In-frameENST00000261819ENST00000301740ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
In-frameENST00000344395ENST00000301740ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
In-frameENST00000535482ENST00000301740ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
In-frameENST00000541887ENST00000301740ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
intron-3CDSENST00000536366ENST00000301740ANAPC5chr12

121766118

-SRRM2chr16

2808985

+
intron-intronENST00000536366ENST00000574593ANAPC5chr12

121766118

-SRRM2chr16

2808985

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000541887ANAPC5chr12121766118-ENST00000301740SRRM2chr162808985+952413134889782976
ENST00000261819ANAPC5chr12121766118-ENST00000301740SRRM2chr162808985+9637142612290912989
ENST00000535482ANAPC5chr12121766118-ENST00000301740SRRM2chr162808985+920299168986562655
ENST00000344395ANAPC5chr12121766118-ENST00000301740SRRM2chr162808985+9179968086332877

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000541887ENST00000301740ANAPC5chr12121766118-SRRM2chr162808985+0.0088964960.99110353
ENST00000261819ENST00000301740ANAPC5chr12121766118-SRRM2chr162808985+0.0090702220.9909298
ENST00000535482ENST00000301740ANAPC5chr12121766118-SRRM2chr162808985+0.0133943560.9866057
ENST00000344395ENST00000301740ANAPC5chr12121766118-SRRM2chr162808985+0.0086652150.99133486

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Fusion Genomic Features for ANAPC5-SRRM2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANAPC5chr12121766118-SRRM2chr162808985+0.196684210.80331576
ANAPC5chr12121766118-SRRM2chr162808985+0.196684210.80331576

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANAPC5-SRRM2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:121766118/chr16:2808985)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANAPC5

Q9UJX4

.
FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269|PubMed:18485873}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017209_249434756.0RepeatNote=TPR 1
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017250_300434756.0RepeatNote=TPR 2
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017301_337434756.0RepeatNote=TPR 3
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017338_378434756.0RepeatNote=TPR 4
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017379_418434756.0RepeatNote=TPR 5
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815209_249322644.0RepeatNote=TPR 1
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815250_300322644.0RepeatNote=TPR 2
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916209_249322644.0RepeatNote=TPR 1
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916250_300322644.0RepeatNote=TPR 2
TgeneSRRM2chr12:121766118chr16:2808985ENST000003017404151666_20891972753.0Compositional biasNote=Arg-rich
TgeneSRRM2chr12:121766118chr16:2808985ENST000003017404152182_23781972753.0Compositional biasNote=Ala-rich
TgeneSRRM2chr12:121766118chr16:2808985ENST000003017404152673_27501972753.0Compositional biasNote=Arg-rich
TgeneSRRM2chr12:121766118chr16:2808985ENST00000301740415350_4471972753.0Compositional biasNote=Pro-rich
TgeneSRRM2chr12:121766118chr16:2808985ENST00000301740415462_8161972753.0Compositional biasNote=Arg-rich
TgeneSRRM2chr12:121766118chr16:2808985ENST00000301740415197_2591972753.0RegionNote=Sufficient for RNA-binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017419_466434756.0RepeatNote=TPR 6
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017467_500434756.0RepeatNote=TPR 7
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017501_540434756.0RepeatNote=TPR 8
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017541_580434756.0RepeatNote=TPR 9
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017581_620434756.0RepeatNote=TPR 10
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017621_660434756.0RepeatNote=TPR 11
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017661_696434756.0RepeatNote=TPR 12
HgeneANAPC5chr12:121766118chr16:2808985ENST00000261819-1017697_736434756.0RepeatNote=TPR 13
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815301_337322644.0RepeatNote=TPR 3
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815338_378322644.0RepeatNote=TPR 4
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815379_418322644.0RepeatNote=TPR 5
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815419_466322644.0RepeatNote=TPR 6
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815467_500322644.0RepeatNote=TPR 7
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815501_540322644.0RepeatNote=TPR 8
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815541_580322644.0RepeatNote=TPR 9
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815581_620322644.0RepeatNote=TPR 10
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815621_660322644.0RepeatNote=TPR 11
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815661_696322644.0RepeatNote=TPR 12
HgeneANAPC5chr12:121766118chr16:2808985ENST00000344395-815697_736322644.0RepeatNote=TPR 13
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916301_337322644.0RepeatNote=TPR 3
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916338_378322644.0RepeatNote=TPR 4
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916379_418322644.0RepeatNote=TPR 5
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916419_466322644.0RepeatNote=TPR 6
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916467_500322644.0RepeatNote=TPR 7
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916501_540322644.0RepeatNote=TPR 8
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916541_580322644.0RepeatNote=TPR 9
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916581_620322644.0RepeatNote=TPR 10
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916621_660322644.0RepeatNote=TPR 11
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916661_696322644.0RepeatNote=TPR 12
HgeneANAPC5chr12:121766118chr16:2808985ENST00000441917-916697_736322644.0RepeatNote=TPR 13
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15209_2490220.0RepeatNote=TPR 1
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15250_3000220.0RepeatNote=TPR 2
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15301_3370220.0RepeatNote=TPR 3
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15338_3780220.0RepeatNote=TPR 4
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15379_4180220.0RepeatNote=TPR 5
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15419_4660220.0RepeatNote=TPR 6
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15467_5000220.0RepeatNote=TPR 7
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15501_5400220.0RepeatNote=TPR 8
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15541_5800220.0RepeatNote=TPR 9
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15581_6200220.0RepeatNote=TPR 10
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15621_6600220.0RepeatNote=TPR 11
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15661_6960220.0RepeatNote=TPR 12
HgeneANAPC5chr12:121766118chr16:2808985ENST00000536366-15697_7360220.0RepeatNote=TPR 13
TgeneSRRM2chr12:121766118chr16:2808985ENST0000030174041560_921972753.0Coiled coilOntology_term=ECO:0000255
TgeneSRRM2chr12:121766118chr16:2808985ENST00000301740415177_27311972753.0Compositional biasNote=Ser-rich
TgeneSRRM2chr12:121766118chr16:2808985ENST00000301740415186_2461972753.0Compositional biasNote=Lys-rich


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Fusion Gene Sequence for ANAPC5-SRRM2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4302_4302_1_ANAPC5-SRRM2_ANAPC5_chr12_121766118_ENST00000261819_SRRM2_chr16_2808985_ENST00000301740_length(transcript)=9637nt_BP=1426nt
GCGGATGTCTGTTTCCTGGGATATTGTGAGGGCGGGCGGAGATGTAGACCCGGTAGTGTTGTGCCTTGTGGTGACAACTGGCGGCAGCGC
GCCGCGGGCCCGAGACTTAGTCTCGGGCCGCCATGGCCAGCGTCCACGAGAGCCTCTACTTCAATCCCATGATGACCAATGGGGTTGTGC
ACGCCAATGTGTTCGGCATCAAGGACTGGGTGACGCCGTACAAGATCGCGGTGCTGGTGCTGCTGAACGAGATGAGCCGCACAGGCGAGG
GCGCCGTCAGCCTCATGGAGCGGCGGAGGCTCAACCAGCTGCTCCTGCCCCTGCTGCAGGGCCCAGATATTACACTGTCAAAACTTTACA
AGTTAATTGAAGAGTCTTGTCCACAGCTGGCAAATTCAGTGCAGATCAGAATCAAACTGATGGCTGAAGGCGAGTTGAAGGATATGGAAC
AGTTTTTTGATGACCTTTCAGATTCTTTCTCTGGAACTGAACCAGAGGTTCACAAAACAAGTGTAGTAGGTTTGTTTCTGCGTCACATGA
TCTTGGCCTACAGTAAGCTTTCTTTCAGCCAAGTGTTTAAACTGTACACTGCCCTTCAGCAGTACTTCCAGAATGGTGAGAAAAAGACAG
TGGAGGATGCTGATATGGAACTGACCAGTAGAGATGAGGGTGAAAGAAAAATGGAAAAAGAAGAACTTGATGTATCTGTAAGAGAAGAGG
AGGTATCTTGCAGTGGGCCTCTGTCCCAAAAACAAGCAGAATTTTTTCTTTCTCAACAGGCTTCTTTGCTAAAGAATGATGAGACTAAGG
CCCTCACTCCAGCTTCCTTGCAGAAGGAATTAAACAATTTGTTGAAATTTAATCCTGATTTTGCTGAAGCGCATTATCTCAGCTACTTAA
ACAACCTCCGTGTCCAAGATGTTTTCAGTTCAACACACAGTCTCCTCCATTATTTTGATCGTCTGATTCTTACCGGAGCCGAAAGCAAAA
GTAATGGGGAAGAGGGCTATGGCCGGAGCTTGAGATACGCCGCTCTGAATCTTGCCGCCCTGCACTGCCGCTTCGGTCACTATCAACAGG
CAGAGCTCGCCCTGCAGGAGGCAATTAGGATTGCCCAGGAGTCCAACGATCACGTGTGTCTCCAGCACTGTTTGAGCTGGCTTTATGTGC
TGGGGCAGAAGAGATCCGATAGCTATGTTCTGCTGGAGCATTCTGTGAAGAAGGCAGTACATTTTGGGTTACCGTACCTCGCCTCCCTGG
GAATACAGTCCCTTGTTCAACAGAGAGCTTTTGCTGGGAAGACGGCAAACAAGCTGATGGATGCCCTAAAGGACTCCGACCTCCTGCACT
GGAAACACAGCCTGTCAGAGCTCATCGATATCAGCATCGCACAGAAAACGGCCATCTGGAGGCTGTATGGCCGCAGCAGGTCAGAGAGCA
GCTCTCCTCGACGGGAGAGAAAGAAAAGCTCAAAGAAGAAGAAGCACAGGTCAGAATCTGAGTCCAAGAAACGTAAGCATAGGTCTCCCA
CTCCAAAGAGCAAACGTAAATCTAAGGACAAAAAGCGAAAGCGGTCTCGAAGTACAACACCAGCCCCCAAGAGCCGCCGGGCCCACCGTT
CAACTTCTGCTGACTCTGCTTCCTCCTCCGATACTTCCCGCAGTCGGTCTCGAAGTGCTGCAGCTAAAACTCATACAACTGCCTTGGCTG
GGCGAAGTCCTTCCCCTGCTTCAGGGCGACGCGGGGAGGGAGATGCGCCTTTCAGTGAACCAGGTACTACCAGCACACAACGGCCTAGTA
GCCCGGAGACTGCTACGAAACAGCCTAGCAGCCCTTATGAAGACAAAGATAAAGACAAGAAGGAGAAATCTGCAACTCGACCTAGCCCCT
CTCCGGAAAGGAGCAGCACAGGCCCAGAACCACCTGCTCCCACTCCGCTCCTTGCTGAGCGACATGGCGGCTCCCCACAACCCCTTGCAA
CCACCCCCTTAAGCCAGGAGCCAGTGAACCCCCCATCTGAGGCCTCTCCAACTCGGGACCGTTCACCACCTAAGTCTCCCGAGAAACTTC
CCCAGTCTTCTTCCTCAGAGAGCAGCCCACCATCCCCTCAACCTACCAAAGTTTCTCGGCATGCCAGCTCTTCCCCAGAAAGTCCTAAAC
CTGCTCCAGCTCCAGGGTCCCACCGAGAGATTTCTTCTTCTCCCACATCTAAGAATCGCTCACATGGCCGAGCAAAACGGGATAAATCAC
ATTCTCATACCCCCTCCCGTAGGATGGGGAGGTCCCGTAGCCCTGCCACCGCTAAGAGAGGGCGATCTCGGTCTCGAACCCCTACCAAGA
GAGGTCATTCTCGATCCCGATCTCCCCAGTGGCGTAGGTCCAGGTCTGCACAGAGGTGGGGAAGATCTAGAAGCCCCCAGCGACGTGGCC
GCTCTAGGTCTCCTCAGCGACCAGGCTGGTCTAGGAGCAGAAATACCCAGAGAAGAGGCAGGTCTAGGTCAGCAAGGCGAGGGAGGTCCC
ACTCTAGATCCCCAGCCACTAGGGGTAGATCTCGTTCTAGAACACCAGCCCGCCGGGGCAGGTCCCGCTCTAGAACACCTGCCAGGCGGA
GATCACGATCCAGAACTCCCACCAGGCGTAGGTCTCGGTCTAGAACACCAGCCCGGAGGGGCAGGTCTCGGTCTAGAACACCTGCTAGGC
GCAGATCTAGGACCCGATCACCAGTACGACGCAGGTCTCGTAGTAGATCACCAGCCAGGAGAAGTGGCAGGTCACGCTCTAGAACCCCAG
CTAGACGTGGCCGCTCACGCTCCAGAACCCCAGCCAGACGTGGCCGCTCACGCTCTAGAACCCCAGCTAGACGCAGTGGTCGCTCACGCT
CCAGAACACCAGCCAGGAGAGGGAGGTCTCGGTCTAGGACACCAAGACGAGGAAGATCCCGCAGTAGAAGCTTAGTTAGACGTGGAAGAT
CTCACTCTAGAACACCTCAAAGAAGAGGCAGATCTGGCTCATCTTCAGAGCGGAAAAACAAATCCAGAACATCTCAAAGAAGAAGCAGGT
CCAATTCAAGCCCAGAAATGAAGAAATCTCGCATTTCTTCAAGGCGGAGCAGGTCTCTCTCTTCACCACGGTCCAAAGCAAAATCTCGCT
TGTCTTTGAGGCGCAGCCTTTCAGGGTCTTCCCCATGCCCTAAACAAAAGTCACAGACACCACCCAGGCGCAGTCGCTCTGGATCCTCCC
AACCTAAAGCTAAATCTAGAACGCCACCCAGACGCAGTCGCTCCAGTTCTTCTCCGCCACCTAAACAGAAATCTAAGACACCATCAAGAC
AAAGTCATTCCAGTTCATCTCCTCATCCTAAAGTGAAATCTGGAACACCACCGAGGCAAGGGTCCATAACAAGTCCCCAGGCCAATGAGC
AATCTGTAACGCCACAGAGACGGAGCTGTTTTGAATCATCACCTGACCCTGAGTTGAAATCTAGGACCCCTTCTAGACATAGCTGCTCAG
GGTCCTCTCCTCCTAGAGTGAAATCTAGCACACCTCCCAGACAGAGCCCATCTAGGTCATCATCTCCACAACCCAAAGTGAAGGCAATAA
TATCACCAAGACAAAGAAGCCATTCTGGCTCCTCTTCTCCAAGTCCTAGTAGGGTGACGTCGAGAACAACTCCACGGCGAAGCAGATCAG
TATCTCCCTGCTCCAATGTGGAATCCAGATTGTTGCCAAGATACAGTCATTCTGGGTCCTCCTCACCAGATACCAAAGTGAAACCTGAAA
CACCGCCAAGACAAAGTCACTCAGGGTCTATTTCACCATACCCCAAAGTAAAGGCCCAAACTCCACCGGGGCCAAGTCTTTCTGGATCAA
AGTCACCATGTCCCCAAGAGAAGTCTAAAGACTCACTAGTTCAAAGTTGCCCTGGATCCCTCTCTCTCTGTGCAGGAGTAAAATCTAGCA
CACCACCAGGCGAGAGCTATTTTGGTGTCTCATCTCTGCAACTGAAAGGACAATCTCAAACTTCACCAGACCACAGATCTGATACTTCAA
GTCCAGAAGTGAGACAGAGTCATTCAGAATCACCATCTCTGCAGAGCAAATCTCAAACATCACCTAAGGGAGGTCGGTCCAGGTCTTCAT
CTCCAGTCACTGAGCTGGCATCCAGATCTCCAATAAGACAAGATAGAGGTGAGTTCTCAGCGAGTCCTATGTTGAAATCTGGAATGTCTC
CTGAGCAGAGCAGGTTCCAGTCTGACTCTTCTTCATATCCTACAGTGGACTCGAATTCTCTCTTGGGGCAGAGTAGATTGGAGACTGCTG
AATCAAAAGAGAAAATGGCCTTACCCCCTCAGGAGGATGCTACTGCATCACCTCCTAGACAGAAAGACAAATTTAGTCCCTTTCCAGTAC
AGGATAGGCCTGAGTCTTCACTGGTATTCAAAGACACACTTAGAACCCCGCCAAGGGAAAGAAGTGGTGCTGGGTCATCTCCAGAAACAA
AAGAGCAAAATAGTGCATTGCCTACGTCAAGCCAAGATGAAGAGTTAATGGAGGTGGTAGAGAAGTCTGAAGAACCCGCAGGCCAAATCC
TGTCTCATTTGTCTTCAGAACTTAAAGAAATGTCCACAAGTAACTTTGAATCATCTCCTGAAGTAGAAGAAAGGCCTGCTGTGTCTTTGA
CTCTTGATCAGAGCCAGTCACAGGCTTCTTTGGAAGCAGTAGAAGTCCCTTCAATGGCCTCATCTTGGGGTGGGCCACATTTTTCTCCAG
AACATAAAGAACTGTCTAACTCCCCACTCAGGGAGAACAGCTTTGGATCACCTTTAGAATTTAGAAACTCAGGCCCACTTGGTACAGAAA
TGAATACTGGATTTTCTTCTGAGGTTAAAGAAGATTTGAATGGACCGTTTCTTAATCAGCTGGAAACAGATCCATCTCTAGACATGAAAG
AACAATCGACAAGATCCTCTGGACACAGCAGTTCTGAGTTATCCCCAGATGCAGTGGAAAAGGCAGGGATGTCTTCAAATCAGAGCATCT
CTTCACCTGTGCTTGATGCTGTACCCAGAACACCCTCGAGAGAAAGAAGTAGTTCTGCATCTTCTCCTGAAATGAAAGATGGTTTACCCA
GAACTCCATCAAGGAGAAGCAGGTCTGGGTCTTCTCCAGGACTTAGAGATGGGTCTGGGACTCCCTCGAGGCACAGCCTGTCTGGGTCCT
CTCCTGGAATGAAAGATATACCTAGAACGCCATCTAGAGGGAGAAGCGAATGTGATTCTTCCCCAGAACCGAAAGCTTTGCCTCAGACTC
CTAGGCCGAGGAGTCGTTCTCCATCATCCCCAGAGCTCAACAACAAGTGTCTTACCCCCCAGAGAGAAAGAAGCGGGTCAGAATCATCAG
TTGATCAGAAAACTGTGGCTCGGACTCCCCTGGGGCAGAGAAGTCGTTCGGGATCCTCTCAAGAACTTGATGTGAAACCCAGTGCATCCC
CTCAGGAAAGAAGTGAGTCAGACTCTTCTCCAGATTCTAAAGCCAAGACAAGAACCCCACTTCGGCAGAGGAGTCGGTCTGGATCATCTC
CAGAGGTTGACAGCAAATCTCGACTATCCCCTCGGCGCAGTAGGTCTGGTTCCTCCCCTGAAGTGAAAGATAAGCCAAGAGCAGCACCCA
GGGCACAGAGTGGTTCTGATTCCTCTCCTGAACCTAAAGCTCCAGCCCCTCGGGCCCTTCCCAGACGAAGCAGATCAGGTTCATCAAGCA
AAGGCAGAGGCCCTTCTCCTGAAGGAAGCAGCAGTACCGAGTCCTCTCCTGAACATCCGCCCAAATCCAGAACTGCTCGCAGAGGTTCCA
GGTCATCACCAGAGCCCAAGACCAAGTCTCGTACACCACCTCGACGTCGCAGCTCTCGATCATCTCCGGAGCTAACAAGGAAGGCCAGAC
TGTCCCGTAGAAGCCGCTCTGCCTCATCCTCACCAGAAACTCGCTCTAGAACTCCCCCAAGGCACCGGAGAAGTCCCTCAGTGTCTTCCC
CGGAGCCAGCCGAAAAATCGAGGTCTTCACGCCGACGGCGCTCAGCTTCATCTCCACGCACTAAGACAACCTCAAGGAGAGGCCGCTCTC
CTTCGCCAAAGCCTCGTGGACTCCAGAGGTCCCGTTCCCGCTCAAGGAGAGAGAAAACAAGAACAACCCGACGTCGAGATAGGTCTGGAT
CTTCTCAGTCAACCTCTCGGCGAAGACAGCGGAGCCGGTCAAGGTCGCGGGTTACTCGGCGGCGGAGGGGAGGCTCTGGTTATCACTCAA
GGTCACCTGCCCGGCAGGAAAGTTCCCGGACCTCCTCTCGACGCCGAAGAGGCCGCTCTCGGACACCCCCAACCAGTCGGAAGCGTTCTC
GCTCACGCACATCACCAGCCCCGTGGAAACGCTCTAGATCTCGAGCCTCTCCAGCCACTCACCGGCGATCCAGGTCCAGAACCCCCCTGA
TAAGCCGACGTAGGTCCAGATCTCGAACTTCACCAGTCAGCCGGAGACGGTCAAGGTCCAGGACTTCAGTGACTCGACGAAGATCCCGGT
CAAGAGCATCCCCAGTGAGCAGAAGGCGATCCAGATCCAGAACGCCACCAGTAACCCGCCGTCGTTCAAGGTCTAGAACGCCAACAACAC
GCCGCCGCTCCCGTTCTAGAACTCCACCAGTGACTCGCAGAAGGTCCAGATCCAGGACTCCACCAGTAACCAGGAGGCGATCTCGAAGCA
GAACTTCGCCTATCACTCGCAGAAGATCAAGATCCAGAACATCTCCGGTCACCCGAAGGAGATCTCGATCTCGCACATCTCCAGTAACTC
GAAGAAGGTCCCGCTCTCGAACCTCACCAGTGACACGCCGCCGCTCTAGGTCCCGGACACCTCCAGCTATTCGGCGCCGCTCTAGATCTC
GAACGCCACTGTTACCACGCAAACGTTCTCGAAGTCGCTCACCACTTGCTATCCGCCGCCGCTCCAGATCCCGTACTCCACGAACAGCTC
GGGGTAAACGGTCCTTAACAAGATCTCCTCCAGCCATCCGCAGGCGTTCTGCATCTGGAAGTAGTTCTGATCGTTCACGATCTGCTACTC
CTCCAGCAACAAGAAATCATTCTGGTTCACGGACACCTCCAGTAGCACTCAACAGTTCCAGAATGAGCTGCTTCAGTCGTCCTAGCATGT
CCCCAACACCTCTTGATCGCTGCAGATCACCTGGAATGCTTGAACCCCTTGGCAGCTCTAGAACACCCATGTCTGTCCTGCAGCAAGCCG
GCGGCTCCATGATGGATGGTCCAGGTCCCCGAATACCTGACCACCAGAGAACATCTGTGCCAGAAAATCATGCTCAGTCCAGGATTGCAC
TTGCCCTGACAGCTATCAGTCTTGGCACCGCTCGGCCTCCTCCGTCCATGTCTGCTGCTGGCCTTGCTGCAAGAATGTCCCAGGTTCCAG
CCCCGGTGCCTCTCATGAGTCTCAGAACCGCACCAGCAGCCAACCTTGCCAGCAGGATTCCTGCAGCCTCTGCGGCAGCCATGAACCTAG
CCAGCGCCAGGACACCTGCCATTCCAACAGCAGTGAACCTGGCTGACTCTCGAACGCCAGCTGCAGCAGCGGCCATGAACTTGGCCAGCC
CCAGAACAGCGGTGGCACCTTCGGCTGTGAACCTGGCTGACCCTCGCACTCCCACAGCCCCAGCTGTGAACCTAGCAGGGGCCAGAACCC
CAGCTGCCTTGGCAGCTCTGAGTCTCACAGGCTCTGGCACACCACCAACTGCTGCAAACTATCCCTCCAGCTCCAGAACACCACAGGCTC
CAGCCTCTGCAAACCTGGTGGGTCCTCGGTCTGCACATGCCACAGCTCCTGTGAATATTGCCGGCTCCAGAACCGCCGCAGCCTTGGCCC
CCGCGAGCCTCACCAGTGCTAGGATGGCTCCAGCATTGTCTGGTGCAAACCTCACCAGCCCCAGGGTGCCCCTTTCTGCCTACGAGCGTG
TCAGTGGCAGAACCTCACCACCGCTCCTTGACCGAGCTAGGTCCAGAACACCACCGTCTGCCCCAAGCCAATCTAGGATGACCTCTGAAC
GGGCTCCCTCCCCTTCCTCTAGAATGGGCCAGGCTCCTTCACAGTCTCTTCTCCCTCCAGCACAGGATCAGCCGAGGTCTCCTGTGCCTT
CTGCTTTTTCAGACCAATCCCGTTGTTTGATTGCCCAGACCACCCCTGTAGCAGGGTCTCAGTCCCTTTCCTCTGGGGCAGTGGCAACGA
CCACGTCCTCTGCTGGTGATCACAATGGCATGCTCTCTGTCCCTGCCCCTGGGGTGCCCCACTCTGATGTGGGGGAGCCACCTGCCTCTA
CTGGGGCCCAGCAGCCTTCTGCATTAGCCGCCCTGCAGCCAGCAAAGGAGCGGCGGAGTTCCTCCTCGTCGTCGTCGTCCTCTAGCTCCT
CCTCTTCTTCATCATCGTCGTCGTCGTCCTCCTCCTCCTCTGGCTCCAGTTCTAGTGACTCAGAGGGCTCTAGCCTTCCTGTGCAACCTG
AGGTGGCACTGAAGAGGGTCCCCAGCCCCACCCCAGCCCCAAAGGAGGCTGTTCGAGAGGGACGTCCTCCGGAGCCAACCCCAGCCAAAC
GGAAGAGGCGCTCTAGCAGTTCCAGTTCCAGCTCCTCCTCTTCATCTTCCTCCTCCTCCTCCTCCTCCTCTTCTTCCTCCTCCTCTTCCT
CTTCTTCTTCTTCCTCCTCATCTTCCTCCTCCTCGTCGTCTTCCTCCCCTTCCCCTGCTAAGCCTGGCCCTCAGGCCTTGCCCAAACCTG
CAAGCCCCAAGAAGCCACCCCCTGGCGAGCGGAGGTCCCGCAGCCCCCGGAAGCCAATAGACTCCCTCAGGGACTCTCGGTCCCTCAGCT
ACTCGCCTGTGGAGCGTCGCCGTCCCTCGCCCCAGCCCTCACCACGGGACCAGCAGAGCAGCAGCAGTGAGCGGGGTTCCCGGAGAGGCC
AGCGTGGGGACAGCCGCTCCCCCAGCCACAAGCGCAGGAGGGAGACACCTAGCCCTCGGCCCATGAGACACCGCTCCTCCAGGTCTCCAT
AAATTGTCTTTGGGGGATTCCACCACACCCAATGCTCTGGAGCCACAAGGAGTGTCCCTTCTTCCCCAGCAGAGCCGTGGGAGGGTCCTT
GTCTGCTCTCCTTTGAACCTTGGCAGCCCTTGGATGGAGGGCTCCCTTTCCCTCCCCTTTTTTTTTTCTTTGTTCCTGTGAAATGTTAAT
CTCCGTGAGTTCTTCCTGGTTCATGTGTTCTGGGGGGTTTGGGGTGGGAGGGAATGCAGATGGGAGTTGGGGGAGGGGAGGATACAGTTC
AGGATACCCCAGCCTGGAGTCAGGGCCAGGGAGGCATGGCCCCACTTGTATCCAGAAGTTCCCAGGGGTGATTGTGATGGTGGTTGGGAC
TGGAGGTTGTATAAGGTGTTCTTGGAAGGAAGGGGCAGGAGTTGGAATTAGTTGGTCCCTACTGTCCCCCATGAGGTTGTGAACCCCTCC
CCCCAACTTTTCATGTTTCTTAAAGGCATTTTGGTTTTTTAAAATCTGTACAGCAAGAGCAACTTTTTCTGTCAAATAAAAATGAGAAAT

>4302_4302_1_ANAPC5-SRRM2_ANAPC5_chr12_121766118_ENST00000261819_SRRM2_chr16_2808985_ENST00000301740_length(amino acids)=2989AA_BP=670
MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLA
NSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR
DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS
THSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL
LEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSRSESSSPRRERKKSS
KKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRR
GEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNP
PSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGR
SRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRS
RSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTP
ARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSR
ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPK
VKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGS
SSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKD
SLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSP
IRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFK
DTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASL
EAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSS
SELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTP
SRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSP
DSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSS
STESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSR
RRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRT
SSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRS
RSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPV
TRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSR
TPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTA
RPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVN
LADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAP
ALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLI
AQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSS
SSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS
SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHK

--------------------------------------------------------------
>4302_4302_2_ANAPC5-SRRM2_ANAPC5_chr12_121766118_ENST00000344395_SRRM2_chr16_2808985_ENST00000301740_length(transcript)=9179nt_BP=968nt
ATGGCTGAAGGCGAGTTGAAGGATATGGAACAGTTTTTTGATGACCTTTCAGATTCTTTCTCTGGAACTGAACCAGAGGTTCACAAAACA
AGTGTAGTAGGTTTGTTTCTGCGTCACATGATCTTGGCCTACAGTAAGCTTTCTTTCAGCCAAGTGTTTAAACTGTACACTGCCCTTCAG
CAGTACTTCCAGAATGGTGAGAAAAAGACAGTGGAGGATGCTGATATGGAACTGACCAGTAGAGATGAGGGTGAAAGAAAAATGGAAAAA
GAAGAACTTGATGTATCTGTAAGAGAAGAGGAGGTATCTTGCAGTGGGCCTCTGTCCCAAAAACAAGCAGAATTTTTTCTTTCTCAACAG
GCTTCTTTGCTAAAGAATGATGAGACTAAGGCCCTCACTCCAGCTTCCTTGCAGAAGGAATTAAACAATTTGTTGAAATTTAATCCTGAT
TTTGCTGAAGCGCATTATCTCAGCTACTTAAACAACCTCCGTGTCCAAGATGTTTTCAGTTCAACACACAGTCTCCTCCATTATTTTGAT
CGTCTGATTCTTACCGGAGCCGAAAGCAAAAGTAATGGGGAAGAGGGCTATGGCCGGAGCTTGAGATACGCCGCTCTGAATCTTGCCGCC
CTGCACTGCCGCTTCGGTCACTATCAACAGGCAGAGCTCGCCCTGCAGGAGGCAATTAGGATTGCCCAGGAGTCCAACGATCACGTGTGT
CTCCAGCACTGTTTGAGCTGGCTTTATGTGCTGGGGCAGAAGAGATCCGATAGCTATGTTCTGCTGGAGCATTCTGTGAAGAAGGCAGTA
CATTTTGGGTTACCGAGAGCTTTTGCTGGGAAGACGGCAAACAAGCTGATGGATGCCCTAAAGGACTCCGACCTCCTGCACTGGAAACAC
AGCCTGTCAGAGCTCATCGATATCAGCATCGCACAGAAAACGGCCATCTGGAGGCTGTATGGCCGCAGCAGGTCAGAGAGCAGCTCTCCT
CGACGGGAGAGAAAGAAAAGCTCAAAGAAGAAGAAGCACAGGTCAGAATCTGAGTCCAAGAAACGTAAGCATAGGTCTCCCACTCCAAAG
AGCAAACGTAAATCTAAGGACAAAAAGCGAAAGCGGTCTCGAAGTACAACACCAGCCCCCAAGAGCCGCCGGGCCCACCGTTCAACTTCT
GCTGACTCTGCTTCCTCCTCCGATACTTCCCGCAGTCGGTCTCGAAGTGCTGCAGCTAAAACTCATACAACTGCCTTGGCTGGGCGAAGT
CCTTCCCCTGCTTCAGGGCGACGCGGGGAGGGAGATGCGCCTTTCAGTGAACCAGGTACTACCAGCACACAACGGCCTAGTAGCCCGGAG
ACTGCTACGAAACAGCCTAGCAGCCCTTATGAAGACAAAGATAAAGACAAGAAGGAGAAATCTGCAACTCGACCTAGCCCCTCTCCGGAA
AGGAGCAGCACAGGCCCAGAACCACCTGCTCCCACTCCGCTCCTTGCTGAGCGACATGGCGGCTCCCCACAACCCCTTGCAACCACCCCC
TTAAGCCAGGAGCCAGTGAACCCCCCATCTGAGGCCTCTCCAACTCGGGACCGTTCACCACCTAAGTCTCCCGAGAAACTTCCCCAGTCT
TCTTCCTCAGAGAGCAGCCCACCATCCCCTCAACCTACCAAAGTTTCTCGGCATGCCAGCTCTTCCCCAGAAAGTCCTAAACCTGCTCCA
GCTCCAGGGTCCCACCGAGAGATTTCTTCTTCTCCCACATCTAAGAATCGCTCACATGGCCGAGCAAAACGGGATAAATCACATTCTCAT
ACCCCCTCCCGTAGGATGGGGAGGTCCCGTAGCCCTGCCACCGCTAAGAGAGGGCGATCTCGGTCTCGAACCCCTACCAAGAGAGGTCAT
TCTCGATCCCGATCTCCCCAGTGGCGTAGGTCCAGGTCTGCACAGAGGTGGGGAAGATCTAGAAGCCCCCAGCGACGTGGCCGCTCTAGG
TCTCCTCAGCGACCAGGCTGGTCTAGGAGCAGAAATACCCAGAGAAGAGGCAGGTCTAGGTCAGCAAGGCGAGGGAGGTCCCACTCTAGA
TCCCCAGCCACTAGGGGTAGATCTCGTTCTAGAACACCAGCCCGCCGGGGCAGGTCCCGCTCTAGAACACCTGCCAGGCGGAGATCACGA
TCCAGAACTCCCACCAGGCGTAGGTCTCGGTCTAGAACACCAGCCCGGAGGGGCAGGTCTCGGTCTAGAACACCTGCTAGGCGCAGATCT
AGGACCCGATCACCAGTACGACGCAGGTCTCGTAGTAGATCACCAGCCAGGAGAAGTGGCAGGTCACGCTCTAGAACCCCAGCTAGACGT
GGCCGCTCACGCTCCAGAACCCCAGCCAGACGTGGCCGCTCACGCTCTAGAACCCCAGCTAGACGCAGTGGTCGCTCACGCTCCAGAACA
CCAGCCAGGAGAGGGAGGTCTCGGTCTAGGACACCAAGACGAGGAAGATCCCGCAGTAGAAGCTTAGTTAGACGTGGAAGATCTCACTCT
AGAACACCTCAAAGAAGAGGCAGATCTGGCTCATCTTCAGAGCGGAAAAACAAATCCAGAACATCTCAAAGAAGAAGCAGGTCCAATTCA
AGCCCAGAAATGAAGAAATCTCGCATTTCTTCAAGGCGGAGCAGGTCTCTCTCTTCACCACGGTCCAAAGCAAAATCTCGCTTGTCTTTG
AGGCGCAGCCTTTCAGGGTCTTCCCCATGCCCTAAACAAAAGTCACAGACACCACCCAGGCGCAGTCGCTCTGGATCCTCCCAACCTAAA
GCTAAATCTAGAACGCCACCCAGACGCAGTCGCTCCAGTTCTTCTCCGCCACCTAAACAGAAATCTAAGACACCATCAAGACAAAGTCAT
TCCAGTTCATCTCCTCATCCTAAAGTGAAATCTGGAACACCACCGAGGCAAGGGTCCATAACAAGTCCCCAGGCCAATGAGCAATCTGTA
ACGCCACAGAGACGGAGCTGTTTTGAATCATCACCTGACCCTGAGTTGAAATCTAGGACCCCTTCTAGACATAGCTGCTCAGGGTCCTCT
CCTCCTAGAGTGAAATCTAGCACACCTCCCAGACAGAGCCCATCTAGGTCATCATCTCCACAACCCAAAGTGAAGGCAATAATATCACCA
AGACAAAGAAGCCATTCTGGCTCCTCTTCTCCAAGTCCTAGTAGGGTGACGTCGAGAACAACTCCACGGCGAAGCAGATCAGTATCTCCC
TGCTCCAATGTGGAATCCAGATTGTTGCCAAGATACAGTCATTCTGGGTCCTCCTCACCAGATACCAAAGTGAAACCTGAAACACCGCCA
AGACAAAGTCACTCAGGGTCTATTTCACCATACCCCAAAGTAAAGGCCCAAACTCCACCGGGGCCAAGTCTTTCTGGATCAAAGTCACCA
TGTCCCCAAGAGAAGTCTAAAGACTCACTAGTTCAAAGTTGCCCTGGATCCCTCTCTCTCTGTGCAGGAGTAAAATCTAGCACACCACCA
GGCGAGAGCTATTTTGGTGTCTCATCTCTGCAACTGAAAGGACAATCTCAAACTTCACCAGACCACAGATCTGATACTTCAAGTCCAGAA
GTGAGACAGAGTCATTCAGAATCACCATCTCTGCAGAGCAAATCTCAAACATCACCTAAGGGAGGTCGGTCCAGGTCTTCATCTCCAGTC
ACTGAGCTGGCATCCAGATCTCCAATAAGACAAGATAGAGGTGAGTTCTCAGCGAGTCCTATGTTGAAATCTGGAATGTCTCCTGAGCAG
AGCAGGTTCCAGTCTGACTCTTCTTCATATCCTACAGTGGACTCGAATTCTCTCTTGGGGCAGAGTAGATTGGAGACTGCTGAATCAAAA
GAGAAAATGGCCTTACCCCCTCAGGAGGATGCTACTGCATCACCTCCTAGACAGAAAGACAAATTTAGTCCCTTTCCAGTACAGGATAGG
CCTGAGTCTTCACTGGTATTCAAAGACACACTTAGAACCCCGCCAAGGGAAAGAAGTGGTGCTGGGTCATCTCCAGAAACAAAAGAGCAA
AATAGTGCATTGCCTACGTCAAGCCAAGATGAAGAGTTAATGGAGGTGGTAGAGAAGTCTGAAGAACCCGCAGGCCAAATCCTGTCTCAT
TTGTCTTCAGAACTTAAAGAAATGTCCACAAGTAACTTTGAATCATCTCCTGAAGTAGAAGAAAGGCCTGCTGTGTCTTTGACTCTTGAT
CAGAGCCAGTCACAGGCTTCTTTGGAAGCAGTAGAAGTCCCTTCAATGGCCTCATCTTGGGGTGGGCCACATTTTTCTCCAGAACATAAA
GAACTGTCTAACTCCCCACTCAGGGAGAACAGCTTTGGATCACCTTTAGAATTTAGAAACTCAGGCCCACTTGGTACAGAAATGAATACT
GGATTTTCTTCTGAGGTTAAAGAAGATTTGAATGGACCGTTTCTTAATCAGCTGGAAACAGATCCATCTCTAGACATGAAAGAACAATCG
ACAAGATCCTCTGGACACAGCAGTTCTGAGTTATCCCCAGATGCAGTGGAAAAGGCAGGGATGTCTTCAAATCAGAGCATCTCTTCACCT
GTGCTTGATGCTGTACCCAGAACACCCTCGAGAGAAAGAAGTAGTTCTGCATCTTCTCCTGAAATGAAAGATGGTTTACCCAGAACTCCA
TCAAGGAGAAGCAGGTCTGGGTCTTCTCCAGGACTTAGAGATGGGTCTGGGACTCCCTCGAGGCACAGCCTGTCTGGGTCCTCTCCTGGA
ATGAAAGATATACCTAGAACGCCATCTAGAGGGAGAAGCGAATGTGATTCTTCCCCAGAACCGAAAGCTTTGCCTCAGACTCCTAGGCCG
AGGAGTCGTTCTCCATCATCCCCAGAGCTCAACAACAAGTGTCTTACCCCCCAGAGAGAAAGAAGCGGGTCAGAATCATCAGTTGATCAG
AAAACTGTGGCTCGGACTCCCCTGGGGCAGAGAAGTCGTTCGGGATCCTCTCAAGAACTTGATGTGAAACCCAGTGCATCCCCTCAGGAA
AGAAGTGAGTCAGACTCTTCTCCAGATTCTAAAGCCAAGACAAGAACCCCACTTCGGCAGAGGAGTCGGTCTGGATCATCTCCAGAGGTT
GACAGCAAATCTCGACTATCCCCTCGGCGCAGTAGGTCTGGTTCCTCCCCTGAAGTGAAAGATAAGCCAAGAGCAGCACCCAGGGCACAG
AGTGGTTCTGATTCCTCTCCTGAACCTAAAGCTCCAGCCCCTCGGGCCCTTCCCAGACGAAGCAGATCAGGTTCATCAAGCAAAGGCAGA
GGCCCTTCTCCTGAAGGAAGCAGCAGTACCGAGTCCTCTCCTGAACATCCGCCCAAATCCAGAACTGCTCGCAGAGGTTCCAGGTCATCA
CCAGAGCCCAAGACCAAGTCTCGTACACCACCTCGACGTCGCAGCTCTCGATCATCTCCGGAGCTAACAAGGAAGGCCAGACTGTCCCGT
AGAAGCCGCTCTGCCTCATCCTCACCAGAAACTCGCTCTAGAACTCCCCCAAGGCACCGGAGAAGTCCCTCAGTGTCTTCCCCGGAGCCA
GCCGAAAAATCGAGGTCTTCACGCCGACGGCGCTCAGCTTCATCTCCACGCACTAAGACAACCTCAAGGAGAGGCCGCTCTCCTTCGCCA
AAGCCTCGTGGACTCCAGAGGTCCCGTTCCCGCTCAAGGAGAGAGAAAACAAGAACAACCCGACGTCGAGATAGGTCTGGATCTTCTCAG
TCAACCTCTCGGCGAAGACAGCGGAGCCGGTCAAGGTCGCGGGTTACTCGGCGGCGGAGGGGAGGCTCTGGTTATCACTCAAGGTCACCT
GCCCGGCAGGAAAGTTCCCGGACCTCCTCTCGACGCCGAAGAGGCCGCTCTCGGACACCCCCAACCAGTCGGAAGCGTTCTCGCTCACGC
ACATCACCAGCCCCGTGGAAACGCTCTAGATCTCGAGCCTCTCCAGCCACTCACCGGCGATCCAGGTCCAGAACCCCCCTGATAAGCCGA
CGTAGGTCCAGATCTCGAACTTCACCAGTCAGCCGGAGACGGTCAAGGTCCAGGACTTCAGTGACTCGACGAAGATCCCGGTCAAGAGCA
TCCCCAGTGAGCAGAAGGCGATCCAGATCCAGAACGCCACCAGTAACCCGCCGTCGTTCAAGGTCTAGAACGCCAACAACACGCCGCCGC
TCCCGTTCTAGAACTCCACCAGTGACTCGCAGAAGGTCCAGATCCAGGACTCCACCAGTAACCAGGAGGCGATCTCGAAGCAGAACTTCG
CCTATCACTCGCAGAAGATCAAGATCCAGAACATCTCCGGTCACCCGAAGGAGATCTCGATCTCGCACATCTCCAGTAACTCGAAGAAGG
TCCCGCTCTCGAACCTCACCAGTGACACGCCGCCGCTCTAGGTCCCGGACACCTCCAGCTATTCGGCGCCGCTCTAGATCTCGAACGCCA
CTGTTACCACGCAAACGTTCTCGAAGTCGCTCACCACTTGCTATCCGCCGCCGCTCCAGATCCCGTACTCCACGAACAGCTCGGGGTAAA
CGGTCCTTAACAAGATCTCCTCCAGCCATCCGCAGGCGTTCTGCATCTGGAAGTAGTTCTGATCGTTCACGATCTGCTACTCCTCCAGCA
ACAAGAAATCATTCTGGTTCACGGACACCTCCAGTAGCACTCAACAGTTCCAGAATGAGCTGCTTCAGTCGTCCTAGCATGTCCCCAACA
CCTCTTGATCGCTGCAGATCACCTGGAATGCTTGAACCCCTTGGCAGCTCTAGAACACCCATGTCTGTCCTGCAGCAAGCCGGCGGCTCC
ATGATGGATGGTCCAGGTCCCCGAATACCTGACCACCAGAGAACATCTGTGCCAGAAAATCATGCTCAGTCCAGGATTGCACTTGCCCTG
ACAGCTATCAGTCTTGGCACCGCTCGGCCTCCTCCGTCCATGTCTGCTGCTGGCCTTGCTGCAAGAATGTCCCAGGTTCCAGCCCCGGTG
CCTCTCATGAGTCTCAGAACCGCACCAGCAGCCAACCTTGCCAGCAGGATTCCTGCAGCCTCTGCGGCAGCCATGAACCTAGCCAGCGCC
AGGACACCTGCCATTCCAACAGCAGTGAACCTGGCTGACTCTCGAACGCCAGCTGCAGCAGCGGCCATGAACTTGGCCAGCCCCAGAACA
GCGGTGGCACCTTCGGCTGTGAACCTGGCTGACCCTCGCACTCCCACAGCCCCAGCTGTGAACCTAGCAGGGGCCAGAACCCCAGCTGCC
TTGGCAGCTCTGAGTCTCACAGGCTCTGGCACACCACCAACTGCTGCAAACTATCCCTCCAGCTCCAGAACACCACAGGCTCCAGCCTCT
GCAAACCTGGTGGGTCCTCGGTCTGCACATGCCACAGCTCCTGTGAATATTGCCGGCTCCAGAACCGCCGCAGCCTTGGCCCCCGCGAGC
CTCACCAGTGCTAGGATGGCTCCAGCATTGTCTGGTGCAAACCTCACCAGCCCCAGGGTGCCCCTTTCTGCCTACGAGCGTGTCAGTGGC
AGAACCTCACCACCGCTCCTTGACCGAGCTAGGTCCAGAACACCACCGTCTGCCCCAAGCCAATCTAGGATGACCTCTGAACGGGCTCCC
TCCCCTTCCTCTAGAATGGGCCAGGCTCCTTCACAGTCTCTTCTCCCTCCAGCACAGGATCAGCCGAGGTCTCCTGTGCCTTCTGCTTTT
TCAGACCAATCCCGTTGTTTGATTGCCCAGACCACCCCTGTAGCAGGGTCTCAGTCCCTTTCCTCTGGGGCAGTGGCAACGACCACGTCC
TCTGCTGGTGATCACAATGGCATGCTCTCTGTCCCTGCCCCTGGGGTGCCCCACTCTGATGTGGGGGAGCCACCTGCCTCTACTGGGGCC
CAGCAGCCTTCTGCATTAGCCGCCCTGCAGCCAGCAAAGGAGCGGCGGAGTTCCTCCTCGTCGTCGTCGTCCTCTAGCTCCTCCTCTTCT
TCATCATCGTCGTCGTCGTCCTCCTCCTCCTCTGGCTCCAGTTCTAGTGACTCAGAGGGCTCTAGCCTTCCTGTGCAACCTGAGGTGGCA
CTGAAGAGGGTCCCCAGCCCCACCCCAGCCCCAAAGGAGGCTGTTCGAGAGGGACGTCCTCCGGAGCCAACCCCAGCCAAACGGAAGAGG
CGCTCTAGCAGTTCCAGTTCCAGCTCCTCCTCTTCATCTTCCTCCTCCTCCTCCTCCTCCTCTTCTTCCTCCTCCTCTTCCTCTTCTTCT
TCTTCCTCCTCATCTTCCTCCTCCTCGTCGTCTTCCTCCCCTTCCCCTGCTAAGCCTGGCCCTCAGGCCTTGCCCAAACCTGCAAGCCCC
AAGAAGCCACCCCCTGGCGAGCGGAGGTCCCGCAGCCCCCGGAAGCCAATAGACTCCCTCAGGGACTCTCGGTCCCTCAGCTACTCGCCT
GTGGAGCGTCGCCGTCCCTCGCCCCAGCCCTCACCACGGGACCAGCAGAGCAGCAGCAGTGAGCGGGGTTCCCGGAGAGGCCAGCGTGGG
GACAGCCGCTCCCCCAGCCACAAGCGCAGGAGGGAGACACCTAGCCCTCGGCCCATGAGACACCGCTCCTCCAGGTCTCCATAAATTGTC
TTTGGGGGATTCCACCACACCCAATGCTCTGGAGCCACAAGGAGTGTCCCTTCTTCCCCAGCAGAGCCGTGGGAGGGTCCTTGTCTGCTC
TCCTTTGAACCTTGGCAGCCCTTGGATGGAGGGCTCCCTTTCCCTCCCCTTTTTTTTTTCTTTGTTCCTGTGAAATGTTAATCTCCGTGA
GTTCTTCCTGGTTCATGTGTTCTGGGGGGTTTGGGGTGGGAGGGAATGCAGATGGGAGTTGGGGGAGGGGAGGATACAGTTCAGGATACC
CCAGCCTGGAGTCAGGGCCAGGGAGGCATGGCCCCACTTGTATCCAGAAGTTCCCAGGGGTGATTGTGATGGTGGTTGGGACTGGAGGTT
GTATAAGGTGTTCTTGGAAGGAAGGGGCAGGAGTTGGAATTAGTTGGTCCCTACTGTCCCCCATGAGGTTGTGAACCCCTCCCCCCAACT

>4302_4302_2_ANAPC5-SRRM2_ANAPC5_chr12_121766118_ENST00000344395_SRRM2_chr16_2808985_ENST00000301740_length(amino acids)=2877AA_BP=558
MAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSRDEGERKMEK
EELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSSTHSLLHYFD
RLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVLLEHSVKKAV
HFGLPRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPK
SKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPE
TATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQS
SSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGH
SRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSR
SRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRT
PARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSL
RRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSV
TPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSP
CSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPP
GESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQ
SRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQ
NSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHK
ELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSP
VLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRP
RSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEV
DSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSS
PEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSP
KPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSR
TSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRR
SRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTP
LLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPT
PLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPV
PLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAA
LAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSG
RTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTS
SAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVA
LKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASP

--------------------------------------------------------------
>4302_4302_3_ANAPC5-SRRM2_ANAPC5_chr12_121766118_ENST00000535482_SRRM2_chr16_2808985_ENST00000301740_length(transcript)=9202nt_BP=991nt
ATTGCCCAGGAGTCCAACGATCACGTGTGTCTCCAGCACTGTTTGGTGAGGCCATCCTCTGGTCTTGGGAGTTTTGTTCACGGGTTGAAT
TGGCCTTCACAAGGCCCCGTTGAATTGGGTTGTTTTGCAGTTGGAGCAGAGATCTTCAGCAGCAAAAGGAAACAAGTTAGGTGGTCATGG
GAATTCAGAAAGGGCAACTTATCTTTACTTACCTTTCTTAATTCATGACATCTGTTTTGCTTTTGGCATATATCTGCTCTACAAAGTTTA
ATGCAACTTGCCATGAAAGAAGAGAAACCTTTATCACATTTAGCACTGGCATTAACAAAAGATGTATACTACACTTAGTAACTGGGTGAG
ATGTTGTCCTGTAATAGCAAAATCACCAGGGCAGTGGAACACAGAAGCTACTTGACAAGCACCTGAGAATCTTATTTCTCAATTGAAGGC
CATATGGGAGCTTCATGCTTTTTTTCTGAAACACCTGCCACTCAGTGGCTGTCAGGTGAAGCAGAACAATGACTCATTTATTTCAGCCTG
GTTTTAATGATGTTGATATGTTTGACAGGTCTCATTGAGATTCTTGATATTTCTTGAAAGAGTATTTGAGAGGATTCATTTTGTCCCTTT
TAAATTCTTTCTTATGACCACATTGATATTTCACTAGAACATCAGCCATTGCCACTGTTATGATATATTTTGATGATTTCTCTTGCCAGA
GCTGGCTTTATGTGCTGGGGCAGAAGAGATCCGATAGCTATGTTCTGCTGGAGCATTCTGTGAAGAAGGCAGTACATTTTGGGTTACCGT
ACCTCGCCTCCCTGGGAATACAGTCCCTTGTTCAACAGAGAGCTTTTGCTGGGAAGACGGCAAACAAGCTGATGGATGCCCTAAAGGACT
CCGACCTCCTGCACTGGAAACACAGCCTGTCAGAGCTCATCGATATCAGCATCGCACAGAAAACGGCCATCTGGAGGCTGTATGGCCGCA
GCAGGTCAGAGAGCAGCTCTCCTCGACGGGAGAGAAAGAAAAGCTCAAAGAAGAAGAAGCACAGGTCAGAATCTGAGTCCAAGAAACGTA
AGCATAGGTCTCCCACTCCAAAGAGCAAACGTAAATCTAAGGACAAAAAGCGAAAGCGGTCTCGAAGTACAACACCAGCCCCCAAGAGCC
GCCGGGCCCACCGTTCAACTTCTGCTGACTCTGCTTCCTCCTCCGATACTTCCCGCAGTCGGTCTCGAAGTGCTGCAGCTAAAACTCATA
CAACTGCCTTGGCTGGGCGAAGTCCTTCCCCTGCTTCAGGGCGACGCGGGGAGGGAGATGCGCCTTTCAGTGAACCAGGTACTACCAGCA
CACAACGGCCTAGTAGCCCGGAGACTGCTACGAAACAGCCTAGCAGCCCTTATGAAGACAAAGATAAAGACAAGAAGGAGAAATCTGCAA
CTCGACCTAGCCCCTCTCCGGAAAGGAGCAGCACAGGCCCAGAACCACCTGCTCCCACTCCGCTCCTTGCTGAGCGACATGGCGGCTCCC
CACAACCCCTTGCAACCACCCCCTTAAGCCAGGAGCCAGTGAACCCCCCATCTGAGGCCTCTCCAACTCGGGACCGTTCACCACCTAAGT
CTCCCGAGAAACTTCCCCAGTCTTCTTCCTCAGAGAGCAGCCCACCATCCCCTCAACCTACCAAAGTTTCTCGGCATGCCAGCTCTTCCC
CAGAAAGTCCTAAACCTGCTCCAGCTCCAGGGTCCCACCGAGAGATTTCTTCTTCTCCCACATCTAAGAATCGCTCACATGGCCGAGCAA
AACGGGATAAATCACATTCTCATACCCCCTCCCGTAGGATGGGGAGGTCCCGTAGCCCTGCCACCGCTAAGAGAGGGCGATCTCGGTCTC
GAACCCCTACCAAGAGAGGTCATTCTCGATCCCGATCTCCCCAGTGGCGTAGGTCCAGGTCTGCACAGAGGTGGGGAAGATCTAGAAGCC
CCCAGCGACGTGGCCGCTCTAGGTCTCCTCAGCGACCAGGCTGGTCTAGGAGCAGAAATACCCAGAGAAGAGGCAGGTCTAGGTCAGCAA
GGCGAGGGAGGTCCCACTCTAGATCCCCAGCCACTAGGGGTAGATCTCGTTCTAGAACACCAGCCCGCCGGGGCAGGTCCCGCTCTAGAA
CACCTGCCAGGCGGAGATCACGATCCAGAACTCCCACCAGGCGTAGGTCTCGGTCTAGAACACCAGCCCGGAGGGGCAGGTCTCGGTCTA
GAACACCTGCTAGGCGCAGATCTAGGACCCGATCACCAGTACGACGCAGGTCTCGTAGTAGATCACCAGCCAGGAGAAGTGGCAGGTCAC
GCTCTAGAACCCCAGCTAGACGTGGCCGCTCACGCTCCAGAACCCCAGCCAGACGTGGCCGCTCACGCTCTAGAACCCCAGCTAGACGCA
GTGGTCGCTCACGCTCCAGAACACCAGCCAGGAGAGGGAGGTCTCGGTCTAGGACACCAAGACGAGGAAGATCCCGCAGTAGAAGCTTAG
TTAGACGTGGAAGATCTCACTCTAGAACACCTCAAAGAAGAGGCAGATCTGGCTCATCTTCAGAGCGGAAAAACAAATCCAGAACATCTC
AAAGAAGAAGCAGGTCCAATTCAAGCCCAGAAATGAAGAAATCTCGCATTTCTTCAAGGCGGAGCAGGTCTCTCTCTTCACCACGGTCCA
AAGCAAAATCTCGCTTGTCTTTGAGGCGCAGCCTTTCAGGGTCTTCCCCATGCCCTAAACAAAAGTCACAGACACCACCCAGGCGCAGTC
GCTCTGGATCCTCCCAACCTAAAGCTAAATCTAGAACGCCACCCAGACGCAGTCGCTCCAGTTCTTCTCCGCCACCTAAACAGAAATCTA
AGACACCATCAAGACAAAGTCATTCCAGTTCATCTCCTCATCCTAAAGTGAAATCTGGAACACCACCGAGGCAAGGGTCCATAACAAGTC
CCCAGGCCAATGAGCAATCTGTAACGCCACAGAGACGGAGCTGTTTTGAATCATCACCTGACCCTGAGTTGAAATCTAGGACCCCTTCTA
GACATAGCTGCTCAGGGTCCTCTCCTCCTAGAGTGAAATCTAGCACACCTCCCAGACAGAGCCCATCTAGGTCATCATCTCCACAACCCA
AAGTGAAGGCAATAATATCACCAAGACAAAGAAGCCATTCTGGCTCCTCTTCTCCAAGTCCTAGTAGGGTGACGTCGAGAACAACTCCAC
GGCGAAGCAGATCAGTATCTCCCTGCTCCAATGTGGAATCCAGATTGTTGCCAAGATACAGTCATTCTGGGTCCTCCTCACCAGATACCA
AAGTGAAACCTGAAACACCGCCAAGACAAAGTCACTCAGGGTCTATTTCACCATACCCCAAAGTAAAGGCCCAAACTCCACCGGGGCCAA
GTCTTTCTGGATCAAAGTCACCATGTCCCCAAGAGAAGTCTAAAGACTCACTAGTTCAAAGTTGCCCTGGATCCCTCTCTCTCTGTGCAG
GAGTAAAATCTAGCACACCACCAGGCGAGAGCTATTTTGGTGTCTCATCTCTGCAACTGAAAGGACAATCTCAAACTTCACCAGACCACA
GATCTGATACTTCAAGTCCAGAAGTGAGACAGAGTCATTCAGAATCACCATCTCTGCAGAGCAAATCTCAAACATCACCTAAGGGAGGTC
GGTCCAGGTCTTCATCTCCAGTCACTGAGCTGGCATCCAGATCTCCAATAAGACAAGATAGAGGTGAGTTCTCAGCGAGTCCTATGTTGA
AATCTGGAATGTCTCCTGAGCAGAGCAGGTTCCAGTCTGACTCTTCTTCATATCCTACAGTGGACTCGAATTCTCTCTTGGGGCAGAGTA
GATTGGAGACTGCTGAATCAAAAGAGAAAATGGCCTTACCCCCTCAGGAGGATGCTACTGCATCACCTCCTAGACAGAAAGACAAATTTA
GTCCCTTTCCAGTACAGGATAGGCCTGAGTCTTCACTGGTATTCAAAGACACACTTAGAACCCCGCCAAGGGAAAGAAGTGGTGCTGGGT
CATCTCCAGAAACAAAAGAGCAAAATAGTGCATTGCCTACGTCAAGCCAAGATGAAGAGTTAATGGAGGTGGTAGAGAAGTCTGAAGAAC
CCGCAGGCCAAATCCTGTCTCATTTGTCTTCAGAACTTAAAGAAATGTCCACAAGTAACTTTGAATCATCTCCTGAAGTAGAAGAAAGGC
CTGCTGTGTCTTTGACTCTTGATCAGAGCCAGTCACAGGCTTCTTTGGAAGCAGTAGAAGTCCCTTCAATGGCCTCATCTTGGGGTGGGC
CACATTTTTCTCCAGAACATAAAGAACTGTCTAACTCCCCACTCAGGGAGAACAGCTTTGGATCACCTTTAGAATTTAGAAACTCAGGCC
CACTTGGTACAGAAATGAATACTGGATTTTCTTCTGAGGTTAAAGAAGATTTGAATGGACCGTTTCTTAATCAGCTGGAAACAGATCCAT
CTCTAGACATGAAAGAACAATCGACAAGATCCTCTGGACACAGCAGTTCTGAGTTATCCCCAGATGCAGTGGAAAAGGCAGGGATGTCTT
CAAATCAGAGCATCTCTTCACCTGTGCTTGATGCTGTACCCAGAACACCCTCGAGAGAAAGAAGTAGTTCTGCATCTTCTCCTGAAATGA
AAGATGGTTTACCCAGAACTCCATCAAGGAGAAGCAGGTCTGGGTCTTCTCCAGGACTTAGAGATGGGTCTGGGACTCCCTCGAGGCACA
GCCTGTCTGGGTCCTCTCCTGGAATGAAAGATATACCTAGAACGCCATCTAGAGGGAGAAGCGAATGTGATTCTTCCCCAGAACCGAAAG
CTTTGCCTCAGACTCCTAGGCCGAGGAGTCGTTCTCCATCATCCCCAGAGCTCAACAACAAGTGTCTTACCCCCCAGAGAGAAAGAAGCG
GGTCAGAATCATCAGTTGATCAGAAAACTGTGGCTCGGACTCCCCTGGGGCAGAGAAGTCGTTCGGGATCCTCTCAAGAACTTGATGTGA
AACCCAGTGCATCCCCTCAGGAAAGAAGTGAGTCAGACTCTTCTCCAGATTCTAAAGCCAAGACAAGAACCCCACTTCGGCAGAGGAGTC
GGTCTGGATCATCTCCAGAGGTTGACAGCAAATCTCGACTATCCCCTCGGCGCAGTAGGTCTGGTTCCTCCCCTGAAGTGAAAGATAAGC
CAAGAGCAGCACCCAGGGCACAGAGTGGTTCTGATTCCTCTCCTGAACCTAAAGCTCCAGCCCCTCGGGCCCTTCCCAGACGAAGCAGAT
CAGGTTCATCAAGCAAAGGCAGAGGCCCTTCTCCTGAAGGAAGCAGCAGTACCGAGTCCTCTCCTGAACATCCGCCCAAATCCAGAACTG
CTCGCAGAGGTTCCAGGTCATCACCAGAGCCCAAGACCAAGTCTCGTACACCACCTCGACGTCGCAGCTCTCGATCATCTCCGGAGCTAA
CAAGGAAGGCCAGACTGTCCCGTAGAAGCCGCTCTGCCTCATCCTCACCAGAAACTCGCTCTAGAACTCCCCCAAGGCACCGGAGAAGTC
CCTCAGTGTCTTCCCCGGAGCCAGCCGAAAAATCGAGGTCTTCACGCCGACGGCGCTCAGCTTCATCTCCACGCACTAAGACAACCTCAA
GGAGAGGCCGCTCTCCTTCGCCAAAGCCTCGTGGACTCCAGAGGTCCCGTTCCCGCTCAAGGAGAGAGAAAACAAGAACAACCCGACGTC
GAGATAGGTCTGGATCTTCTCAGTCAACCTCTCGGCGAAGACAGCGGAGCCGGTCAAGGTCGCGGGTTACTCGGCGGCGGAGGGGAGGCT
CTGGTTATCACTCAAGGTCACCTGCCCGGCAGGAAAGTTCCCGGACCTCCTCTCGACGCCGAAGAGGCCGCTCTCGGACACCCCCAACCA
GTCGGAAGCGTTCTCGCTCACGCACATCACCAGCCCCGTGGAAACGCTCTAGATCTCGAGCCTCTCCAGCCACTCACCGGCGATCCAGGT
CCAGAACCCCCCTGATAAGCCGACGTAGGTCCAGATCTCGAACTTCACCAGTCAGCCGGAGACGGTCAAGGTCCAGGACTTCAGTGACTC
GACGAAGATCCCGGTCAAGAGCATCCCCAGTGAGCAGAAGGCGATCCAGATCCAGAACGCCACCAGTAACCCGCCGTCGTTCAAGGTCTA
GAACGCCAACAACACGCCGCCGCTCCCGTTCTAGAACTCCACCAGTGACTCGCAGAAGGTCCAGATCCAGGACTCCACCAGTAACCAGGA
GGCGATCTCGAAGCAGAACTTCGCCTATCACTCGCAGAAGATCAAGATCCAGAACATCTCCGGTCACCCGAAGGAGATCTCGATCTCGCA
CATCTCCAGTAACTCGAAGAAGGTCCCGCTCTCGAACCTCACCAGTGACACGCCGCCGCTCTAGGTCCCGGACACCTCCAGCTATTCGGC
GCCGCTCTAGATCTCGAACGCCACTGTTACCACGCAAACGTTCTCGAAGTCGCTCACCACTTGCTATCCGCCGCCGCTCCAGATCCCGTA
CTCCACGAACAGCTCGGGGTAAACGGTCCTTAACAAGATCTCCTCCAGCCATCCGCAGGCGTTCTGCATCTGGAAGTAGTTCTGATCGTT
CACGATCTGCTACTCCTCCAGCAACAAGAAATCATTCTGGTTCACGGACACCTCCAGTAGCACTCAACAGTTCCAGAATGAGCTGCTTCA
GTCGTCCTAGCATGTCCCCAACACCTCTTGATCGCTGCAGATCACCTGGAATGCTTGAACCCCTTGGCAGCTCTAGAACACCCATGTCTG
TCCTGCAGCAAGCCGGCGGCTCCATGATGGATGGTCCAGGTCCCCGAATACCTGACCACCAGAGAACATCTGTGCCAGAAAATCATGCTC
AGTCCAGGATTGCACTTGCCCTGACAGCTATCAGTCTTGGCACCGCTCGGCCTCCTCCGTCCATGTCTGCTGCTGGCCTTGCTGCAAGAA
TGTCCCAGGTTCCAGCCCCGGTGCCTCTCATGAGTCTCAGAACCGCACCAGCAGCCAACCTTGCCAGCAGGATTCCTGCAGCCTCTGCGG
CAGCCATGAACCTAGCCAGCGCCAGGACACCTGCCATTCCAACAGCAGTGAACCTGGCTGACTCTCGAACGCCAGCTGCAGCAGCGGCCA
TGAACTTGGCCAGCCCCAGAACAGCGGTGGCACCTTCGGCTGTGAACCTGGCTGACCCTCGCACTCCCACAGCCCCAGCTGTGAACCTAG
CAGGGGCCAGAACCCCAGCTGCCTTGGCAGCTCTGAGTCTCACAGGCTCTGGCACACCACCAACTGCTGCAAACTATCCCTCCAGCTCCA
GAACACCACAGGCTCCAGCCTCTGCAAACCTGGTGGGTCCTCGGTCTGCACATGCCACAGCTCCTGTGAATATTGCCGGCTCCAGAACCG
CCGCAGCCTTGGCCCCCGCGAGCCTCACCAGTGCTAGGATGGCTCCAGCATTGTCTGGTGCAAACCTCACCAGCCCCAGGGTGCCCCTTT
CTGCCTACGAGCGTGTCAGTGGCAGAACCTCACCACCGCTCCTTGACCGAGCTAGGTCCAGAACACCACCGTCTGCCCCAAGCCAATCTA
GGATGACCTCTGAACGGGCTCCCTCCCCTTCCTCTAGAATGGGCCAGGCTCCTTCACAGTCTCTTCTCCCTCCAGCACAGGATCAGCCGA
GGTCTCCTGTGCCTTCTGCTTTTTCAGACCAATCCCGTTGTTTGATTGCCCAGACCACCCCTGTAGCAGGGTCTCAGTCCCTTTCCTCTG
GGGCAGTGGCAACGACCACGTCCTCTGCTGGTGATCACAATGGCATGCTCTCTGTCCCTGCCCCTGGGGTGCCCCACTCTGATGTGGGGG
AGCCACCTGCCTCTACTGGGGCCCAGCAGCCTTCTGCATTAGCCGCCCTGCAGCCAGCAAAGGAGCGGCGGAGTTCCTCCTCGTCGTCGT
CGTCCTCTAGCTCCTCCTCTTCTTCATCATCGTCGTCGTCGTCCTCCTCCTCCTCTGGCTCCAGTTCTAGTGACTCAGAGGGCTCTAGCC
TTCCTGTGCAACCTGAGGTGGCACTGAAGAGGGTCCCCAGCCCCACCCCAGCCCCAAAGGAGGCTGTTCGAGAGGGACGTCCTCCGGAGC
CAACCCCAGCCAAACGGAAGAGGCGCTCTAGCAGTTCCAGTTCCAGCTCCTCCTCTTCATCTTCCTCCTCCTCCTCCTCCTCCTCTTCTT
CCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCATCTTCCTCCTCCTCGTCGTCTTCCTCCCCTTCCCCTGCTAAGCCTGGCCCTCAGG
CCTTGCCCAAACCTGCAAGCCCCAAGAAGCCACCCCCTGGCGAGCGGAGGTCCCGCAGCCCCCGGAAGCCAATAGACTCCCTCAGGGACT
CTCGGTCCCTCAGCTACTCGCCTGTGGAGCGTCGCCGTCCCTCGCCCCAGCCCTCACCACGGGACCAGCAGAGCAGCAGCAGTGAGCGGG
GTTCCCGGAGAGGCCAGCGTGGGGACAGCCGCTCCCCCAGCCACAAGCGCAGGAGGGAGACACCTAGCCCTCGGCCCATGAGACACCGCT
CCTCCAGGTCTCCATAAATTGTCTTTGGGGGATTCCACCACACCCAATGCTCTGGAGCCACAAGGAGTGTCCCTTCTTCCCCAGCAGAGC
CGTGGGAGGGTCCTTGTCTGCTCTCCTTTGAACCTTGGCAGCCCTTGGATGGAGGGCTCCCTTTCCCTCCCCTTTTTTTTTTCTTTGTTC
CTGTGAAATGTTAATCTCCGTGAGTTCTTCCTGGTTCATGTGTTCTGGGGGGTTTGGGGTGGGAGGGAATGCAGATGGGAGTTGGGGGAG
GGGAGGATACAGTTCAGGATACCCCAGCCTGGAGTCAGGGCCAGGGAGGCATGGCCCCACTTGTATCCAGAAGTTCCCAGGGGTGATTGT
GATGGTGGTTGGGACTGGAGGTTGTATAAGGTGTTCTTGGAAGGAAGGGGCAGGAGTTGGAATTAGTTGGTCCCTACTGTCCCCCATGAG
GTTGTGAACCCCTCCCCCCAACTTTTCATGTTTCTTAAAGGCATTTTGGTTTTTTAAAATCTGTACAGCAAGAGCAACTTTTTCTGTCAA

>4302_4302_3_ANAPC5-SRRM2_ANAPC5_chr12_121766118_ENST00000535482_SRRM2_chr16_2808985_ENST00000301740_length(amino acids)=2655AA_BP=336
MIYFDDFSCQSWLYVLGQKRSDSYVLLEHSVKKAVHFGLPYLASLGIQSLVQQRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQ
KTAIWRLYGRSRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRS
RSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPT
PLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSP
TSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRN
TQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRS
RSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSS
SERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRS
SSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQ
SPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYP
KVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLCAGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQ
SKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPMLKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDAT
ASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGAGSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSN
FESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWGGPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNG
PFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGMSSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGL
RDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRS
RSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAP
APRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETR
SRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSR
SRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSR
RRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTS
PVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRR
RSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDH
QRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAARMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLA
DSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVNLAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHAT
APVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVPLSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQ
SLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLSSGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPA
KERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSS
SSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSP

--------------------------------------------------------------
>4302_4302_4_ANAPC5-SRRM2_ANAPC5_chr12_121766118_ENST00000541887_SRRM2_chr16_2808985_ENST00000301740_length(transcript)=9524nt_BP=1313nt
CAACTGGCGGCAGCGCGCCGCGGGCCCGAGACTTAGTCTCGGGCCGCCATGGCCAGCGTCCACGAGAGCCTCTACTTCAATCCCATGATG
ACCAATGGGGTTGTGCACGCCAATGTGTTCGGCATCAAGGACTGGGTGACGCCGTACAAGATCGCGGTGCTGGTGCTGCTGAACGAGATG
AGCCGCACAGGCGAGGGCGCCGTCAGCCTCATGGAGCGGCGGAGGCTCAACCAGCTGCTCCTGCCCCTGCTGCAGGGCCCAGATATTACA
CTGTCAAAACTTTACAAGTTAATTGAAGAGTCTTGTCCACAGCTGGCAAATTCAGTGCAGATCAGAATCAAACTGATGGCTGAAGGCGAG
TTGAAGGATATGGAACAGTTTTTTGATGACCTTTCAGATTCTTTCTCTGGAACTGAACCAGAGGTTCACAAAACAAGTGTAGTAGGTTTG
TTTCTGCGTCACATGATCTTGGCCTACAGTAAGCTTTCTTTCAGCCAAGTGTTTAAACTGTACACTGCCCTTCAGCAGTACTTCCAGAAT
GGTGAGAAAAAGACAGTGGAGGATGCTGATATGGAACTGACCAGTAGAGATGAGGGTGAAAGAAAAATGGAAAAAGAAGAACTTGATGTA
TCTGTAAGAGAAGAGGAGGTATCTTGCAGTGGGCCTCTGTCCCAAAAACAAGCAGAATTTTTTCTTTCTCAACAGGCTTCTTTGCTAAAG
AATGATGAGACTAAGGCCCTCACTCCAGCTTCCTTGCAGAAGGAATTAAACAATTTGTTGAAATTTAATCCTGATTTTGCTGAAGCGCAT
TATCTCAGCTACTTAAACAACCTCCGTGTCCAAGATGTTTTCAGTTCAACACACAGTCTCCTCCATTATTTTGATCGTCTGATTCTTACC
GGAGCCGAAAGCAAAAGTAATGGGGAAGAGGGCTATGGCCGGAGCTTGAGATACGCCGCTCTGAATCTTGCCGCCCTGCACTGCCGCTTC
GGTCACTATCAACAGGCAGAGCTCGCCCTGCAGGAGGCAATTAGGATTGCCCAGGAGTCCAACGATCACGTGTGTCTCCAGCACTGTTTG
AGCTGGCTTTATGTGCTGGGGCAGAAGAGATCCGATAGCTATGTTCTGCTGGAGCATTCTGTGAAGAAGGCAGTACATTTTGGGTTACCG
AGAGCTTTTGCTGGGAAGACGGCAAACAAGCTGATGGATGCCCTAAAGGACTCCGACCTCCTGCACTGGAAACACAGCCTGTCAGAGCTC
ATCGATATCAGCATCGCACAGAAAACGGCCATCTGGAGGCTGTATGGCCGCAGCAGGTCAGAGAGCAGCTCTCCTCGACGGGAGAGAAAG
AAAAGCTCAAAGAAGAAGAAGCACAGGTCAGAATCTGAGTCCAAGAAACGTAAGCATAGGTCTCCCACTCCAAAGAGCAAACGTAAATCT
AAGGACAAAAAGCGAAAGCGGTCTCGAAGTACAACACCAGCCCCCAAGAGCCGCCGGGCCCACCGTTCAACTTCTGCTGACTCTGCTTCC
TCCTCCGATACTTCCCGCAGTCGGTCTCGAAGTGCTGCAGCTAAAACTCATACAACTGCCTTGGCTGGGCGAAGTCCTTCCCCTGCTTCA
GGGCGACGCGGGGAGGGAGATGCGCCTTTCAGTGAACCAGGTACTACCAGCACACAACGGCCTAGTAGCCCGGAGACTGCTACGAAACAG
CCTAGCAGCCCTTATGAAGACAAAGATAAAGACAAGAAGGAGAAATCTGCAACTCGACCTAGCCCCTCTCCGGAAAGGAGCAGCACAGGC
CCAGAACCACCTGCTCCCACTCCGCTCCTTGCTGAGCGACATGGCGGCTCCCCACAACCCCTTGCAACCACCCCCTTAAGCCAGGAGCCA
GTGAACCCCCCATCTGAGGCCTCTCCAACTCGGGACCGTTCACCACCTAAGTCTCCCGAGAAACTTCCCCAGTCTTCTTCCTCAGAGAGC
AGCCCACCATCCCCTCAACCTACCAAAGTTTCTCGGCATGCCAGCTCTTCCCCAGAAAGTCCTAAACCTGCTCCAGCTCCAGGGTCCCAC
CGAGAGATTTCTTCTTCTCCCACATCTAAGAATCGCTCACATGGCCGAGCAAAACGGGATAAATCACATTCTCATACCCCCTCCCGTAGG
ATGGGGAGGTCCCGTAGCCCTGCCACCGCTAAGAGAGGGCGATCTCGGTCTCGAACCCCTACCAAGAGAGGTCATTCTCGATCCCGATCT
CCCCAGTGGCGTAGGTCCAGGTCTGCACAGAGGTGGGGAAGATCTAGAAGCCCCCAGCGACGTGGCCGCTCTAGGTCTCCTCAGCGACCA
GGCTGGTCTAGGAGCAGAAATACCCAGAGAAGAGGCAGGTCTAGGTCAGCAAGGCGAGGGAGGTCCCACTCTAGATCCCCAGCCACTAGG
GGTAGATCTCGTTCTAGAACACCAGCCCGCCGGGGCAGGTCCCGCTCTAGAACACCTGCCAGGCGGAGATCACGATCCAGAACTCCCACC
AGGCGTAGGTCTCGGTCTAGAACACCAGCCCGGAGGGGCAGGTCTCGGTCTAGAACACCTGCTAGGCGCAGATCTAGGACCCGATCACCA
GTACGACGCAGGTCTCGTAGTAGATCACCAGCCAGGAGAAGTGGCAGGTCACGCTCTAGAACCCCAGCTAGACGTGGCCGCTCACGCTCC
AGAACCCCAGCCAGACGTGGCCGCTCACGCTCTAGAACCCCAGCTAGACGCAGTGGTCGCTCACGCTCCAGAACACCAGCCAGGAGAGGG
AGGTCTCGGTCTAGGACACCAAGACGAGGAAGATCCCGCAGTAGAAGCTTAGTTAGACGTGGAAGATCTCACTCTAGAACACCTCAAAGA
AGAGGCAGATCTGGCTCATCTTCAGAGCGGAAAAACAAATCCAGAACATCTCAAAGAAGAAGCAGGTCCAATTCAAGCCCAGAAATGAAG
AAATCTCGCATTTCTTCAAGGCGGAGCAGGTCTCTCTCTTCACCACGGTCCAAAGCAAAATCTCGCTTGTCTTTGAGGCGCAGCCTTTCA
GGGTCTTCCCCATGCCCTAAACAAAAGTCACAGACACCACCCAGGCGCAGTCGCTCTGGATCCTCCCAACCTAAAGCTAAATCTAGAACG
CCACCCAGACGCAGTCGCTCCAGTTCTTCTCCGCCACCTAAACAGAAATCTAAGACACCATCAAGACAAAGTCATTCCAGTTCATCTCCT
CATCCTAAAGTGAAATCTGGAACACCACCGAGGCAAGGGTCCATAACAAGTCCCCAGGCCAATGAGCAATCTGTAACGCCACAGAGACGG
AGCTGTTTTGAATCATCACCTGACCCTGAGTTGAAATCTAGGACCCCTTCTAGACATAGCTGCTCAGGGTCCTCTCCTCCTAGAGTGAAA
TCTAGCACACCTCCCAGACAGAGCCCATCTAGGTCATCATCTCCACAACCCAAAGTGAAGGCAATAATATCACCAAGACAAAGAAGCCAT
TCTGGCTCCTCTTCTCCAAGTCCTAGTAGGGTGACGTCGAGAACAACTCCACGGCGAAGCAGATCAGTATCTCCCTGCTCCAATGTGGAA
TCCAGATTGTTGCCAAGATACAGTCATTCTGGGTCCTCCTCACCAGATACCAAAGTGAAACCTGAAACACCGCCAAGACAAAGTCACTCA
GGGTCTATTTCACCATACCCCAAAGTAAAGGCCCAAACTCCACCGGGGCCAAGTCTTTCTGGATCAAAGTCACCATGTCCCCAAGAGAAG
TCTAAAGACTCACTAGTTCAAAGTTGCCCTGGATCCCTCTCTCTCTGTGCAGGAGTAAAATCTAGCACACCACCAGGCGAGAGCTATTTT
GGTGTCTCATCTCTGCAACTGAAAGGACAATCTCAAACTTCACCAGACCACAGATCTGATACTTCAAGTCCAGAAGTGAGACAGAGTCAT
TCAGAATCACCATCTCTGCAGAGCAAATCTCAAACATCACCTAAGGGAGGTCGGTCCAGGTCTTCATCTCCAGTCACTGAGCTGGCATCC
AGATCTCCAATAAGACAAGATAGAGGTGAGTTCTCAGCGAGTCCTATGTTGAAATCTGGAATGTCTCCTGAGCAGAGCAGGTTCCAGTCT
GACTCTTCTTCATATCCTACAGTGGACTCGAATTCTCTCTTGGGGCAGAGTAGATTGGAGACTGCTGAATCAAAAGAGAAAATGGCCTTA
CCCCCTCAGGAGGATGCTACTGCATCACCTCCTAGACAGAAAGACAAATTTAGTCCCTTTCCAGTACAGGATAGGCCTGAGTCTTCACTG
GTATTCAAAGACACACTTAGAACCCCGCCAAGGGAAAGAAGTGGTGCTGGGTCATCTCCAGAAACAAAAGAGCAAAATAGTGCATTGCCT
ACGTCAAGCCAAGATGAAGAGTTAATGGAGGTGGTAGAGAAGTCTGAAGAACCCGCAGGCCAAATCCTGTCTCATTTGTCTTCAGAACTT
AAAGAAATGTCCACAAGTAACTTTGAATCATCTCCTGAAGTAGAAGAAAGGCCTGCTGTGTCTTTGACTCTTGATCAGAGCCAGTCACAG
GCTTCTTTGGAAGCAGTAGAAGTCCCTTCAATGGCCTCATCTTGGGGTGGGCCACATTTTTCTCCAGAACATAAAGAACTGTCTAACTCC
CCACTCAGGGAGAACAGCTTTGGATCACCTTTAGAATTTAGAAACTCAGGCCCACTTGGTACAGAAATGAATACTGGATTTTCTTCTGAG
GTTAAAGAAGATTTGAATGGACCGTTTCTTAATCAGCTGGAAACAGATCCATCTCTAGACATGAAAGAACAATCGACAAGATCCTCTGGA
CACAGCAGTTCTGAGTTATCCCCAGATGCAGTGGAAAAGGCAGGGATGTCTTCAAATCAGAGCATCTCTTCACCTGTGCTTGATGCTGTA
CCCAGAACACCCTCGAGAGAAAGAAGTAGTTCTGCATCTTCTCCTGAAATGAAAGATGGTTTACCCAGAACTCCATCAAGGAGAAGCAGG
TCTGGGTCTTCTCCAGGACTTAGAGATGGGTCTGGGACTCCCTCGAGGCACAGCCTGTCTGGGTCCTCTCCTGGAATGAAAGATATACCT
AGAACGCCATCTAGAGGGAGAAGCGAATGTGATTCTTCCCCAGAACCGAAAGCTTTGCCTCAGACTCCTAGGCCGAGGAGTCGTTCTCCA
TCATCCCCAGAGCTCAACAACAAGTGTCTTACCCCCCAGAGAGAAAGAAGCGGGTCAGAATCATCAGTTGATCAGAAAACTGTGGCTCGG
ACTCCCCTGGGGCAGAGAAGTCGTTCGGGATCCTCTCAAGAACTTGATGTGAAACCCAGTGCATCCCCTCAGGAAAGAAGTGAGTCAGAC
TCTTCTCCAGATTCTAAAGCCAAGACAAGAACCCCACTTCGGCAGAGGAGTCGGTCTGGATCATCTCCAGAGGTTGACAGCAAATCTCGA
CTATCCCCTCGGCGCAGTAGGTCTGGTTCCTCCCCTGAAGTGAAAGATAAGCCAAGAGCAGCACCCAGGGCACAGAGTGGTTCTGATTCC
TCTCCTGAACCTAAAGCTCCAGCCCCTCGGGCCCTTCCCAGACGAAGCAGATCAGGTTCATCAAGCAAAGGCAGAGGCCCTTCTCCTGAA
GGAAGCAGCAGTACCGAGTCCTCTCCTGAACATCCGCCCAAATCCAGAACTGCTCGCAGAGGTTCCAGGTCATCACCAGAGCCCAAGACC
AAGTCTCGTACACCACCTCGACGTCGCAGCTCTCGATCATCTCCGGAGCTAACAAGGAAGGCCAGACTGTCCCGTAGAAGCCGCTCTGCC
TCATCCTCACCAGAAACTCGCTCTAGAACTCCCCCAAGGCACCGGAGAAGTCCCTCAGTGTCTTCCCCGGAGCCAGCCGAAAAATCGAGG
TCTTCACGCCGACGGCGCTCAGCTTCATCTCCACGCACTAAGACAACCTCAAGGAGAGGCCGCTCTCCTTCGCCAAAGCCTCGTGGACTC
CAGAGGTCCCGTTCCCGCTCAAGGAGAGAGAAAACAAGAACAACCCGACGTCGAGATAGGTCTGGATCTTCTCAGTCAACCTCTCGGCGA
AGACAGCGGAGCCGGTCAAGGTCGCGGGTTACTCGGCGGCGGAGGGGAGGCTCTGGTTATCACTCAAGGTCACCTGCCCGGCAGGAAAGT
TCCCGGACCTCCTCTCGACGCCGAAGAGGCCGCTCTCGGACACCCCCAACCAGTCGGAAGCGTTCTCGCTCACGCACATCACCAGCCCCG
TGGAAACGCTCTAGATCTCGAGCCTCTCCAGCCACTCACCGGCGATCCAGGTCCAGAACCCCCCTGATAAGCCGACGTAGGTCCAGATCT
CGAACTTCACCAGTCAGCCGGAGACGGTCAAGGTCCAGGACTTCAGTGACTCGACGAAGATCCCGGTCAAGAGCATCCCCAGTGAGCAGA
AGGCGATCCAGATCCAGAACGCCACCAGTAACCCGCCGTCGTTCAAGGTCTAGAACGCCAACAACACGCCGCCGCTCCCGTTCTAGAACT
CCACCAGTGACTCGCAGAAGGTCCAGATCCAGGACTCCACCAGTAACCAGGAGGCGATCTCGAAGCAGAACTTCGCCTATCACTCGCAGA
AGATCAAGATCCAGAACATCTCCGGTCACCCGAAGGAGATCTCGATCTCGCACATCTCCAGTAACTCGAAGAAGGTCCCGCTCTCGAACC
TCACCAGTGACACGCCGCCGCTCTAGGTCCCGGACACCTCCAGCTATTCGGCGCCGCTCTAGATCTCGAACGCCACTGTTACCACGCAAA
CGTTCTCGAAGTCGCTCACCACTTGCTATCCGCCGCCGCTCCAGATCCCGTACTCCACGAACAGCTCGGGGTAAACGGTCCTTAACAAGA
TCTCCTCCAGCCATCCGCAGGCGTTCTGCATCTGGAAGTAGTTCTGATCGTTCACGATCTGCTACTCCTCCAGCAACAAGAAATCATTCT
GGTTCACGGACACCTCCAGTAGCACTCAACAGTTCCAGAATGAGCTGCTTCAGTCGTCCTAGCATGTCCCCAACACCTCTTGATCGCTGC
AGATCACCTGGAATGCTTGAACCCCTTGGCAGCTCTAGAACACCCATGTCTGTCCTGCAGCAAGCCGGCGGCTCCATGATGGATGGTCCA
GGTCCCCGAATACCTGACCACCAGAGAACATCTGTGCCAGAAAATCATGCTCAGTCCAGGATTGCACTTGCCCTGACAGCTATCAGTCTT
GGCACCGCTCGGCCTCCTCCGTCCATGTCTGCTGCTGGCCTTGCTGCAAGAATGTCCCAGGTTCCAGCCCCGGTGCCTCTCATGAGTCTC
AGAACCGCACCAGCAGCCAACCTTGCCAGCAGGATTCCTGCAGCCTCTGCGGCAGCCATGAACCTAGCCAGCGCCAGGACACCTGCCATT
CCAACAGCAGTGAACCTGGCTGACTCTCGAACGCCAGCTGCAGCAGCGGCCATGAACTTGGCCAGCCCCAGAACAGCGGTGGCACCTTCG
GCTGTGAACCTGGCTGACCCTCGCACTCCCACAGCCCCAGCTGTGAACCTAGCAGGGGCCAGAACCCCAGCTGCCTTGGCAGCTCTGAGT
CTCACAGGCTCTGGCACACCACCAACTGCTGCAAACTATCCCTCCAGCTCCAGAACACCACAGGCTCCAGCCTCTGCAAACCTGGTGGGT
CCTCGGTCTGCACATGCCACAGCTCCTGTGAATATTGCCGGCTCCAGAACCGCCGCAGCCTTGGCCCCCGCGAGCCTCACCAGTGCTAGG
ATGGCTCCAGCATTGTCTGGTGCAAACCTCACCAGCCCCAGGGTGCCCCTTTCTGCCTACGAGCGTGTCAGTGGCAGAACCTCACCACCG
CTCCTTGACCGAGCTAGGTCCAGAACACCACCGTCTGCCCCAAGCCAATCTAGGATGACCTCTGAACGGGCTCCCTCCCCTTCCTCTAGA
ATGGGCCAGGCTCCTTCACAGTCTCTTCTCCCTCCAGCACAGGATCAGCCGAGGTCTCCTGTGCCTTCTGCTTTTTCAGACCAATCCCGT
TGTTTGATTGCCCAGACCACCCCTGTAGCAGGGTCTCAGTCCCTTTCCTCTGGGGCAGTGGCAACGACCACGTCCTCTGCTGGTGATCAC
AATGGCATGCTCTCTGTCCCTGCCCCTGGGGTGCCCCACTCTGATGTGGGGGAGCCACCTGCCTCTACTGGGGCCCAGCAGCCTTCTGCA
TTAGCCGCCCTGCAGCCAGCAAAGGAGCGGCGGAGTTCCTCCTCGTCGTCGTCGTCCTCTAGCTCCTCCTCTTCTTCATCATCGTCGTCG
TCGTCCTCCTCCTCCTCTGGCTCCAGTTCTAGTGACTCAGAGGGCTCTAGCCTTCCTGTGCAACCTGAGGTGGCACTGAAGAGGGTCCCC
AGCCCCACCCCAGCCCCAAAGGAGGCTGTTCGAGAGGGACGTCCTCCGGAGCCAACCCCAGCCAAACGGAAGAGGCGCTCTAGCAGTTCC
AGTTCCAGCTCCTCCTCTTCATCTTCCTCCTCCTCCTCCTCCTCCTCTTCTTCCTCCTCCTCTTCCTCTTCTTCTTCTTCCTCCTCATCT
TCCTCCTCCTCGTCGTCTTCCTCCCCTTCCCCTGCTAAGCCTGGCCCTCAGGCCTTGCCCAAACCTGCAAGCCCCAAGAAGCCACCCCCT
GGCGAGCGGAGGTCCCGCAGCCCCCGGAAGCCAATAGACTCCCTCAGGGACTCTCGGTCCCTCAGCTACTCGCCTGTGGAGCGTCGCCGT
CCCTCGCCCCAGCCCTCACCACGGGACCAGCAGAGCAGCAGCAGTGAGCGGGGTTCCCGGAGAGGCCAGCGTGGGGACAGCCGCTCCCCC
AGCCACAAGCGCAGGAGGGAGACACCTAGCCCTCGGCCCATGAGACACCGCTCCTCCAGGTCTCCATAAATTGTCTTTGGGGGATTCCAC
CACACCCAATGCTCTGGAGCCACAAGGAGTGTCCCTTCTTCCCCAGCAGAGCCGTGGGAGGGTCCTTGTCTGCTCTCCTTTGAACCTTGG
CAGCCCTTGGATGGAGGGCTCCCTTTCCCTCCCCTTTTTTTTTTCTTTGTTCCTGTGAAATGTTAATCTCCGTGAGTTCTTCCTGGTTCA
TGTGTTCTGGGGGGTTTGGGGTGGGAGGGAATGCAGATGGGAGTTGGGGGAGGGGAGGATACAGTTCAGGATACCCCAGCCTGGAGTCAG
GGCCAGGGAGGCATGGCCCCACTTGTATCCAGAAGTTCCCAGGGGTGATTGTGATGGTGGTTGGGACTGGAGGTTGTATAAGGTGTTCTT
GGAAGGAAGGGGCAGGAGTTGGAATTAGTTGGTCCCTACTGTCCCCCATGAGGTTGTGAACCCCTCCCCCCAACTTTTCATGTTTCTTAA

>4302_4302_4_ANAPC5-SRRM2_ANAPC5_chr12_121766118_ENST00000541887_SRRM2_chr16_2808985_ENST00000301740_length(amino acids)=2976AA_BP=657
MASVHESLYFNPMMTNGVVHANVFGIKDWVTPYKIAVLVLLNEMSRTGEGAVSLMERRRLNQLLLPLLQGPDITLSKLYKLIEESCPQLA
NSVQIRIKLMAEGELKDMEQFFDDLSDSFSGTEPEVHKTSVVGLFLRHMILAYSKLSFSQVFKLYTALQQYFQNGEKKTVEDADMELTSR
DEGERKMEKEELDVSVREEEVSCSGPLSQKQAEFFLSQQASLLKNDETKALTPASLQKELNNLLKFNPDFAEAHYLSYLNNLRVQDVFSS
THSLLHYFDRLILTGAESKSNGEEGYGRSLRYAALNLAALHCRFGHYQQAELALQEAIRIAQESNDHVCLQHCLSWLYVLGQKRSDSYVL
LEHSVKKAVHFGLPRAFAGKTANKLMDALKDSDLLHWKHSLSELIDISIAQKTAIWRLYGRSRSESSSPRRERKKSSKKKKHRSESESKK
RKHRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTT
STQRPSSPETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRSPP
KSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAKRGRSR
SRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS
RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPAR
RSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSSPR
SKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSIT
SPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTT
PRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISPYPKVKAQTPPGPSLSGSKSPCPQEKSKDSLVQSCPGSLSLC
AGVKSSTPPGESYFGVSSLQLKGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIRQDRGEFSASPM
LKSGMSPEQSRFQSDSSSYPTVDSNSLLGQSRLETAESKEKMALPPQEDATASPPRQKDKFSPFPVQDRPESSLVFKDTLRTPPRERSGA
GSSPETKEQNSALPTSSQDEELMEVVEKSEEPAGQILSHLSSELKEMSTSNFESSPEVEERPAVSLTLDQSQSQASLEAVEVPSMASSWG
GPHFSPEHKELSNSPLRENSFGSPLEFRNSGPLGTEMNTGFSSEVKEDLNGPFLNQLETDPSLDMKEQSTRSSGHSSSELSPDAVEKAGM
SSNQSISSPVLDAVPRTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEP
KALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSESDSSPDSKAKTRTPLRQR
SRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSR
TARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTT
SRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP
TSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSR
SRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTPPAI
RRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNSSRMSC
FSRPSMSPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQRTSVPENHAQSRIALALTAISLGTARPPPSMSAAGLAA
RMSQVPAPVPLMSLRTAPAANLASRIPAASAAAMNLASARTPAIPTAVNLADSRTPAAAAAMNLASPRTAVAPSAVNLADPRTPTAPAVN
LAGARTPAALAALSLTGSGTPPTAANYPSSSRTPQAPASANLVGPRSAHATAPVNIAGSRTAAALAPASLTSARMAPALSGANLTSPRVP
LSAYERVSGRTSPPLLDRARSRTPPSAPSQSRMTSERAPSPSSRMGQAPSQSLLPPAQDQPRSPVPSAFSDQSRCLIAQTTPVAGSQSLS
SGAVATTTSSAGDHNGMLSVPAPGVPHSDVGEPPASTGAQQPSALAALQPAKERRSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGS
SLPVQPEVALKRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSPSPAKPGP
QALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRH

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ANAPC5-SRRM2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANAPC5-SRRM2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANAPC5-SRRM2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource