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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:KLHL7-BRAF (FusionGDB2 ID:43033)

Fusion Gene Summary for KLHL7-BRAF

check button Fusion gene summary
Fusion gene informationFusion gene name: KLHL7-BRAF
Fusion gene ID: 43033
HgeneTgene
Gene symbol

KLHL7

BRAF

Gene ID

55975

673

Gene namekelch like family member 7B-Raf proto-oncogene, serine/threonine kinase
SynonymsCISS3|KLHL6|PERCHING|SBBI26B-RAF1|B-raf|BRAF1|NS7|RAFB1
Cytomap

7p15.3

7q34

Type of geneprotein-codingprotein-coding
Descriptionkelch-like protein 7kelch-like 6kelch-like 7kelch/BTBserine/threonine-protein kinase B-raf94 kDa B-raf proteinB-Raf proto-oncogene serine/threonine-protein kinase (p94)B-Raf serine/threonine-proteinmurine sarcoma viral (v-raf) oncogene homolog B1proto-oncogene B-Rafv-raf murine sarcoma viral oncogene
Modification date2020032720200329
UniProtAcc.

P15056

Ensembl transtripts involved in fusion geneENST00000410047, ENST00000322275, 
ENST00000322231, ENST00000339077, 
ENST00000409689, ENST00000479288, 
ENST00000539124, ENST00000542558, 
ENST00000545443, ENST00000545771, 
ENST00000288602, 
Fusion gene scores* DoF score6 X 7 X 3=12648 X 58 X 16=44544
# samples 869
** MAII scorelog2(8/126*10)=-0.655351828612554
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(69/44544*10)=-6.0124909441832
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KLHL7 [Title/Abstract] AND BRAF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKLHL7(23165418)-BRAF(140482957), # samples:2
Anticipated loss of major functional domain due to fusion event.KLHL7-BRAF seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
KLHL7-BRAF seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
KLHL7-BRAF seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
KLHL7-BRAF seems lost the major protein functional domain in Tgene partner, which is a kinase due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKLHL7

GO:0016567

protein ubiquitination

21828050

TgeneBRAF

GO:0000186

activation of MAPKK activity

29433126

TgeneBRAF

GO:0006468

protein phosphorylation

17563371

TgeneBRAF

GO:0010828

positive regulation of glucose transmembrane transport

23010278

TgeneBRAF

GO:0033138

positive regulation of peptidyl-serine phosphorylation

19667065

TgeneBRAF

GO:0043066

negative regulation of apoptotic process

19667065

TgeneBRAF

GO:0070374

positive regulation of ERK1 and ERK2 cascade

22065586

TgeneBRAF

GO:0071277

cellular response to calcium ion

18567582

TgeneBRAF

GO:0090150

establishment of protein localization to membrane

23010278


check buttonFusion gene breakpoints across KLHL7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BRAF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4GBMTCGA-28-5218-01AKLHL7chr7

23165418

+BRAFchr7

140482957

-


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Fusion Gene ORF analysis for KLHL7-BRAF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000410047ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-
In-frameENST00000322275ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-
intron-3CDSENST00000322231ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-
intron-3CDSENST00000339077ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-
intron-3CDSENST00000409689ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-
intron-3CDSENST00000479288ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-
intron-3CDSENST00000539124ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-
intron-3CDSENST00000542558ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-
intron-3CDSENST00000545443ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-
intron-3CDSENST00000545771ENST00000288602KLHL7chr7

23165418

+BRAFchr7

140482957

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000322275KLHL7chr723165418+ENST00000288602BRAFchr7140482957-21729309442053369

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000322275ENST00000288602KLHL7chr723165418+BRAFchr7140482957-0.0023847350.99761534

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Fusion Genomic Features for KLHL7-BRAF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KLHL7-BRAF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:23165418/chr7:140482957)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.BRAF

P15056

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Protein kinase involved in the transduction of mitogenic signals from the cell membrane to the nucleus (Probable). Phosphorylates MAP2K1, and thereby activates the MAP kinase signal transduction pathway (PubMed:21441910, PubMed:29433126). May play a role in the postsynaptic responses of hippocampal neurons (PubMed:1508179). {ECO:0000269|PubMed:1508179, ECO:0000269|PubMed:21441910, ECO:0000269|PubMed:29433126, ECO:0000305}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneBRAFchr7:23165418chr7:140482957ENST00000288602818428_432392767.0Compositional biasNote=Poly-Ser
TgeneBRAFchr7:23165418chr7:140482957ENST00000288602818457_717392767.0DomainProtein kinase
TgeneBRAFchr7:23165418chr7:140482957ENST00000288602818463_471392767.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322231+112146_2480565.0DomainNote=BACK
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322231+11244_1110565.0DomainBTB
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322275+15146_2480167.0DomainNote=BACK
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322275+1544_1110167.0DomainBTB
HgeneKLHL7chr7:23165418chr7:140482957ENST00000339077+111146_2480587.0DomainNote=BACK
HgeneKLHL7chr7:23165418chr7:140482957ENST00000339077+11144_1110587.0DomainBTB
HgeneKLHL7chr7:23165418chr7:140482957ENST00000409689+111146_2480539.0DomainNote=BACK
HgeneKLHL7chr7:23165418chr7:140482957ENST00000409689+11144_1110539.0DomainBTB
HgeneKLHL7chr7:23165418chr7:140482957ENST00000410047+16146_2480145.0DomainNote=BACK
HgeneKLHL7chr7:23165418chr7:140482957ENST00000410047+1644_1110145.0DomainBTB
HgeneKLHL7chr7:23165418chr7:140482957ENST00000545443+111146_2480565.0DomainNote=BACK
HgeneKLHL7chr7:23165418chr7:140482957ENST00000545443+11144_1110565.0DomainBTB
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322231+112294_3360565.0RepeatNote=Kelch 1
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322231+112337_3820565.0RepeatNote=Kelch 2
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322231+112383_4300565.0RepeatNote=Kelch 3
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322231+112431_4810565.0RepeatNote=Kelch 4
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322231+112483_5280565.0RepeatNote=Kelch 5
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322231+112530_5750565.0RepeatNote=Kelch 6
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322275+15294_3360167.0RepeatNote=Kelch 1
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322275+15337_3820167.0RepeatNote=Kelch 2
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322275+15383_4300167.0RepeatNote=Kelch 3
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322275+15431_4810167.0RepeatNote=Kelch 4
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322275+15483_5280167.0RepeatNote=Kelch 5
HgeneKLHL7chr7:23165418chr7:140482957ENST00000322275+15530_5750167.0RepeatNote=Kelch 6
HgeneKLHL7chr7:23165418chr7:140482957ENST00000339077+111294_3360587.0RepeatNote=Kelch 1
HgeneKLHL7chr7:23165418chr7:140482957ENST00000339077+111337_3820587.0RepeatNote=Kelch 2
HgeneKLHL7chr7:23165418chr7:140482957ENST00000339077+111383_4300587.0RepeatNote=Kelch 3
HgeneKLHL7chr7:23165418chr7:140482957ENST00000339077+111431_4810587.0RepeatNote=Kelch 4
HgeneKLHL7chr7:23165418chr7:140482957ENST00000339077+111483_5280587.0RepeatNote=Kelch 5
HgeneKLHL7chr7:23165418chr7:140482957ENST00000339077+111530_5750587.0RepeatNote=Kelch 6
HgeneKLHL7chr7:23165418chr7:140482957ENST00000409689+111294_3360539.0RepeatNote=Kelch 1
HgeneKLHL7chr7:23165418chr7:140482957ENST00000409689+111337_3820539.0RepeatNote=Kelch 2
HgeneKLHL7chr7:23165418chr7:140482957ENST00000409689+111383_4300539.0RepeatNote=Kelch 3
HgeneKLHL7chr7:23165418chr7:140482957ENST00000409689+111431_4810539.0RepeatNote=Kelch 4
HgeneKLHL7chr7:23165418chr7:140482957ENST00000409689+111483_5280539.0RepeatNote=Kelch 5
HgeneKLHL7chr7:23165418chr7:140482957ENST00000409689+111530_5750539.0RepeatNote=Kelch 6
HgeneKLHL7chr7:23165418chr7:140482957ENST00000410047+16294_3360145.0RepeatNote=Kelch 1
HgeneKLHL7chr7:23165418chr7:140482957ENST00000410047+16337_3820145.0RepeatNote=Kelch 2
HgeneKLHL7chr7:23165418chr7:140482957ENST00000410047+16383_4300145.0RepeatNote=Kelch 3
HgeneKLHL7chr7:23165418chr7:140482957ENST00000410047+16431_4810145.0RepeatNote=Kelch 4
HgeneKLHL7chr7:23165418chr7:140482957ENST00000410047+16483_5280145.0RepeatNote=Kelch 5
HgeneKLHL7chr7:23165418chr7:140482957ENST00000410047+16530_5750145.0RepeatNote=Kelch 6
HgeneKLHL7chr7:23165418chr7:140482957ENST00000545443+111294_3360565.0RepeatNote=Kelch 1
HgeneKLHL7chr7:23165418chr7:140482957ENST00000545443+111337_3820565.0RepeatNote=Kelch 2
HgeneKLHL7chr7:23165418chr7:140482957ENST00000545443+111383_4300565.0RepeatNote=Kelch 3
HgeneKLHL7chr7:23165418chr7:140482957ENST00000545443+111431_4810565.0RepeatNote=Kelch 4
HgeneKLHL7chr7:23165418chr7:140482957ENST00000545443+111483_5280565.0RepeatNote=Kelch 5
HgeneKLHL7chr7:23165418chr7:140482957ENST00000545443+111530_5750565.0RepeatNote=Kelch 6
TgeneBRAFchr7:23165418chr7:140482957ENST00000288602818122_129392767.0Compositional biasNote=Poly-Ser
TgeneBRAFchr7:23165418chr7:140482957ENST000002886028186_11392767.0Compositional biasNote=Poly-Gly
TgeneBRAFchr7:23165418chr7:140482957ENST00000288602818155_227392767.0DomainRBD
TgeneBRAFchr7:23165418chr7:140482957ENST00000288602818234_280392767.0Zinc fingerPhorbol-ester/DAG-type


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Fusion Gene Sequence for KLHL7-BRAF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>43033_43033_1_KLHL7-BRAF_KLHL7_chr7_23165418_ENST00000322275_BRAF_chr7_140482957_ENST00000288602_length(transcript)=2172nt_BP=930nt
GGGTTCTGCCCGGGGACGCAGCCCAGTTGGTAGCGTCGCTCCCTGAGCGTTTCTAAGGGGGCCGCCCGGCCTTGTCTTTCGGCAGTGGCC
GAGCCACCGCCGCCTGCCGCGCGTTCCAGAGCTGGGCGCTGCAGCTGCACTGCCGATCGCCGTGTTTGGTCGATAGAATCCCCAGTGTGC
CCAGAGAGTGCGACCCCTCGCCCGGCCCGGCGAGCCCCGGGCGTGAACCGAGCTGAGGGAGGATGGCAGCCTCTGGGGTGGAGAAGAGCA
GCAAGAAGAAGACCGAGAAGAAACTTGCTGCTCGGGAAGAAGCTAAATTGTTGGCGGGTTTCATGGGCGTCATGAATAACATGCGGAAAC
AGAAAACGTTGTGTGACGTGATCCTCATGGTCCAGGAAAGAAAGATACCTGCTCATCGTGTTGTTCTTGCTGCAGCCAGTCATTTTTTTA
ACTTAATGTTCACAACTAACATGCTTGAATCAAAGTCCTTTGAAGTAGAACTCAAAGATGCTGAACCTGATATTATTGAACAACTGGTGG
AATTTGCTTATACTGCTAGAATTTCCGTGAATAGCAACAATGTTCAGTCTTTGCTGGATGCAGCAAACCAATATCAGATTGAACCTGTGA
AGAAAATGTGTGTTGATTTTTTGAAAGAACAAGTTGATGCTTCAAATTGTCTTGGTATGCTTTTCACTGTGTGATGATCCTTAGTGGCAC
ATGAATGAACGTCCAGATGTTTGTGCAGTAGCCCACCCTTATCTGCAGGATACGTTCCAAGACCCCCAGTGAATGCCTGAAACTGCAGAT
AGTACTGAATCCTATATATACTGTGTTTTTTATGATACATACATGCCTATGATGAAGTTTAATTTCTAAATTAGACAGTAAAAGATTAAC
AACAATAATAATAAAATAGAACAACTTTAAGATCAACCACAGGTTTGTCTGCTACCCCCCCTGCCTCATTACCTGGCTCACTAACTAACG
TGAAAGCCTTACAGAAATCTCCAGGACCTCAGCGAGAAAGGAAGTCATCTTCATCCTCAGAAGACAGGAATCGAATGAAAACACTTGGTA
GACGGGACTCGAGTGATGATTGGGAGATTCCTGATGGGCAGATTACAGTGGGACAAAGAATTGGATCTGGATCATTTGGAACAGTCTACA
AGGGAAAGTGGCATGGTGATGTGGCAGTGAAAATGTTGAATGTGACAGCACCTACACCTCAGCAGTTACAAGCCTTCAAAAATGAAGTAG
GAGTACTCAGGAAAACACGACATGTGAATATCCTACTCTTCATGGGCTATTCCACAAAGCCACAACTGGCTATTGTTACCCAGTGGTGTG
AGGGCTCCAGCTTGTATCACCATCTCCATATCATTGAGACCAAATTTGAGATGATCAAACTTATAGATATTGCACGACAGACTGCACAGG
GCATGGATTACTTACACGCCAAGTCAATCATCCACAGAGACCTCAAGAGTAATAATATATTTCTTCATGAAGACCTCACAGTAAAAATAG
GTGATTTTGGTCTAGCTACAGTGAAATCTCGATGGAGTGGGTCCCATCAGTTTGAACAGTTGTCTGGATCCATTTTGTGGATGGCACCAG
AAGTCATCAGAATGCAAGATAAAAATCCATACAGCTTTCAGTCAGATGTATATGCATTTGGAATTGTTCTGTATGAATTGATGACTGGAC
AGTTACCTTATTCAAACATCAACAACAGGGACCAGATAATTTTTATGGTGGGACGAGGATACCTGTCTCCAGATCTCAGTAAGGTACGGA
GTAACTGTCCAAAAGCCATGAAGAGATTAATGGCAGAGTGCCTCAAAAAGAAAAGAGATGAGAGACCACTCTTTCCCCAAATTCTCGCCT
CTATTGAGCTGCTGGCCCGCTCATTGCCAAAAATTCACCGCAGTGCATCAGAACCCTCCTTGAATCGGGCTGGTTTCCAAACAGAGGATT
TTAGTCTATATGCTTGTGCTTCTCCAAAAACACCCATCCAGGCAGGGGGATATGGTGCGTTTCCTGTCCACTGAAACAAATGAGTGAGAG
AGTTCAGGAGAGTAGCAACAAAAGGAAAATAAATGAACATATGTTTGCTTATATGTTAAATTGAATAAAATACTCTCTTTTTTTTTAAGG

>43033_43033_1_KLHL7-BRAF_KLHL7_chr7_23165418_ENST00000322275_BRAF_chr7_140482957_ENST00000288602_length(amino acids)=369AA_BP=
MSATPPASLPGSLTNVKALQKSPGPQRERKSSSSSEDRNRMKTLGRRDSSDDWEIPDGQITVGQRIGSGSFGTVYKGKWHGDVAVKMLNV
TAPTPQQLQAFKNEVGVLRKTRHVNILLFMGYSTKPQLAIVTQWCEGSSLYHHLHIIETKFEMIKLIDIARQTAQGMDYLHAKSIIHRDL
KSNNIFLHEDLTVKIGDFGLATVKSRWSGSHQFEQLSGSILWMAPEVIRMQDKNPYSFQSDVYAFGIVLYELMTGQLPYSNINNRDQIIF
MVGRGYLSPDLSKVRSNCPKAMKRLMAECLKKKRDERPLFPQILASIELLARSLPKIHRSASEPSLNRAGFQTEDFSLYACASPKTPIQA

--------------------------------------------------------------

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Fusion Gene PPI Analysis for KLHL7-BRAF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for KLHL7-BRAF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for KLHL7-BRAF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource