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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:KMT2A-AFF4 (FusionGDB2 ID:43140) |
Fusion Gene Summary for KMT2A-AFF4 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: KMT2A-AFF4 | Fusion gene ID: 43140 | Hgene | Tgene | Gene symbol | KMT2A | AFF4 | Gene ID | 4297 | 27125 |
| Gene name | lysine methyltransferase 2A | AF4/FMR2 family member 4 | |
| Synonyms | ALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTS | AF5Q31|CHOPS|MCEF | |
| Cytomap | 11q23.3 | 5q31.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | histone-lysine N-methyltransferase 2ACXXC-type zinc finger protein 7lysine (K)-specific methyltransferase 2Alysine N-methyltransferase 2Amixed lineage leukemia 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)trithorax-like | AF4/FMR2 family member 4ALL1-fused gene from chromosome 5q31 proteinmajor CDK9 elongation factor-associated protein | |
| Modification date | 20200319 | 20200315 | |
| UniProtAcc | Q03164 | Q9UHB7 | |
| Ensembl transtripts involved in fusion gene | ENST00000420751, ENST00000354520, ENST00000389506, ENST00000534358, | ENST00000265343, ENST00000378595, ENST00000491831, | |
| Fusion gene scores | * DoF score | 79 X 196 X 13=201292 | 8 X 9 X 3=216 |
| # samples | 241 | 8 | |
| ** MAII score | log2(241/201292*10)=-6.38411287931608 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(8/216*10)=-1.43295940727611 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: KMT2A [Title/Abstract] AND AFF4 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | |||
| Anticipated loss of major functional domain due to fusion event. | KMT2A-AFF4 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. KMT2A-AFF4 seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF. KMT2A-AFF4 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. KMT2A-AFF4 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. KMT2A-AFF4 seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF. KMT2A-AFF4 seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | KMT2A | GO:0044648 | histone H3-K4 dimethylation | 25561738 |
| Hgene | KMT2A | GO:0045944 | positive regulation of transcription by RNA polymerase II | 20861184 |
| Hgene | KMT2A | GO:0051568 | histone H3-K4 methylation | 19556245 |
| Hgene | KMT2A | GO:0065003 | protein-containing complex assembly | 15199122 |
| Hgene | KMT2A | GO:0080182 | histone H3-K4 trimethylation | 20861184 |
| Hgene | KMT2A | GO:0097692 | histone H3-K4 monomethylation | 25561738|26324722 |
| Fusion gene breakpoints across KMT2A (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene breakpoints across AFF4 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerKB3 | . | . | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| ChimerKB3 | . | . | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| ChimerKB3 | . | . | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| ChimerKB3 | . | . | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
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Fusion Gene ORF analysis for KMT2A-AFF4 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 3UTR-3CDS | ENST00000420751 | ENST00000265343 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| 3UTR-3CDS | ENST00000420751 | ENST00000265343 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| 3UTR-3CDS | ENST00000420751 | ENST00000378595 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| 3UTR-3CDS | ENST00000420751 | ENST00000378595 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| 3UTR-5UTR | ENST00000420751 | ENST00000491831 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| 3UTR-5UTR | ENST00000420751 | ENST00000491831 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| 5CDS-5UTR | ENST00000354520 | ENST00000491831 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| 5CDS-5UTR | ENST00000354520 | ENST00000491831 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| 5CDS-5UTR | ENST00000354520 | ENST00000491831 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| 5CDS-5UTR | ENST00000354520 | ENST00000491831 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| 5CDS-5UTR | ENST00000389506 | ENST00000491831 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| 5CDS-5UTR | ENST00000389506 | ENST00000491831 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| 5CDS-5UTR | ENST00000389506 | ENST00000491831 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| 5CDS-5UTR | ENST00000389506 | ENST00000491831 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| 5CDS-5UTR | ENST00000534358 | ENST00000491831 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| 5CDS-5UTR | ENST00000534358 | ENST00000491831 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| 5CDS-5UTR | ENST00000534358 | ENST00000491831 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| 5CDS-5UTR | ENST00000534358 | ENST00000491831 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| Frame-shift | ENST00000354520 | ENST00000265343 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| Frame-shift | ENST00000354520 | ENST00000378595 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| Frame-shift | ENST00000389506 | ENST00000265343 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| Frame-shift | ENST00000389506 | ENST00000378595 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| Frame-shift | ENST00000534358 | ENST00000265343 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| Frame-shift | ENST00000534358 | ENST00000378595 | KMT2A | chr11 | 118352807 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000354520 | ENST00000265343 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000354520 | ENST00000265343 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| In-frame | ENST00000354520 | ENST00000265343 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000354520 | ENST00000378595 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000354520 | ENST00000378595 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| In-frame | ENST00000354520 | ENST00000378595 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000389506 | ENST00000265343 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000389506 | ENST00000265343 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| In-frame | ENST00000389506 | ENST00000265343 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000389506 | ENST00000378595 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000389506 | ENST00000378595 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| In-frame | ENST00000389506 | ENST00000378595 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000534358 | ENST00000265343 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000534358 | ENST00000265343 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| In-frame | ENST00000534358 | ENST00000265343 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000534358 | ENST00000378595 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| In-frame | ENST00000534358 | ENST00000378595 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| In-frame | ENST00000534358 | ENST00000378595 | KMT2A | chr11 | 118355029 | + | AFF4 | chr5 | 132240096 | - |
| intron-3CDS | ENST00000420751 | ENST00000265343 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| intron-3CDS | ENST00000420751 | ENST00000265343 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| intron-3CDS | ENST00000420751 | ENST00000378595 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| intron-3CDS | ENST00000420751 | ENST00000378595 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| intron-5UTR | ENST00000420751 | ENST00000491831 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132240096 | - |
| intron-5UTR | ENST00000420751 | ENST00000491831 | KMT2A | chr11 | 118353210 | + | AFF4 | chr5 | 132262899 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000534358 | KMT2A | chr11 | 118353210 | + | ENST00000265343 | AFF4 | chr5 | 132262899 | - | 12318 | 4109 | 23 | 6637 | 2204 |
| ENST00000534358 | KMT2A | chr11 | 118353210 | + | ENST00000378595 | AFF4 | chr5 | 132262899 | - | 6130 | 4109 | 23 | 5848 | 1941 |
| ENST00000389506 | KMT2A | chr11 | 118353210 | + | ENST00000265343 | AFF4 | chr5 | 132262899 | - | 12295 | 4086 | 0 | 6614 | 2204 |
| ENST00000389506 | KMT2A | chr11 | 118353210 | + | ENST00000378595 | AFF4 | chr5 | 132262899 | - | 6107 | 4086 | 0 | 5825 | 1941 |
| ENST00000354520 | KMT2A | chr11 | 118353210 | + | ENST00000265343 | AFF4 | chr5 | 132262899 | - | 12295 | 4086 | 0 | 6614 | 2204 |
| ENST00000354520 | KMT2A | chr11 | 118353210 | + | ENST00000378595 | AFF4 | chr5 | 132262899 | - | 6107 | 4086 | 0 | 5825 | 1941 |
| ENST00000534358 | KMT2A | chr11 | 118353210 | + | ENST00000265343 | AFF4 | chr5 | 132240096 | - | 12231 | 4109 | 23 | 6550 | 2175 |
| ENST00000534358 | KMT2A | chr11 | 118353210 | + | ENST00000378595 | AFF4 | chr5 | 132240096 | - | 6043 | 4109 | 23 | 5761 | 1912 |
| ENST00000389506 | KMT2A | chr11 | 118353210 | + | ENST00000265343 | AFF4 | chr5 | 132240096 | - | 12208 | 4086 | 0 | 6527 | 2175 |
| ENST00000389506 | KMT2A | chr11 | 118353210 | + | ENST00000378595 | AFF4 | chr5 | 132240096 | - | 6020 | 4086 | 0 | 5738 | 1912 |
| ENST00000354520 | KMT2A | chr11 | 118353210 | + | ENST00000265343 | AFF4 | chr5 | 132240096 | - | 12208 | 4086 | 0 | 6527 | 2175 |
| ENST00000354520 | KMT2A | chr11 | 118353210 | + | ENST00000378595 | AFF4 | chr5 | 132240096 | - | 6020 | 4086 | 0 | 5738 | 1912 |
| ENST00000534358 | KMT2A | chr11 | 118355029 | + | ENST00000265343 | AFF4 | chr5 | 132240096 | - | 12363 | 4241 | 23 | 6682 | 2219 |
| ENST00000534358 | KMT2A | chr11 | 118355029 | + | ENST00000378595 | AFF4 | chr5 | 132240096 | - | 6175 | 4241 | 23 | 5893 | 1956 |
| ENST00000389506 | KMT2A | chr11 | 118355029 | + | ENST00000265343 | AFF4 | chr5 | 132240096 | - | 12340 | 4218 | 0 | 6659 | 2219 |
| ENST00000389506 | KMT2A | chr11 | 118355029 | + | ENST00000378595 | AFF4 | chr5 | 132240096 | - | 6152 | 4218 | 0 | 5870 | 1956 |
| ENST00000354520 | KMT2A | chr11 | 118355029 | + | ENST00000265343 | AFF4 | chr5 | 132240096 | - | 12340 | 4218 | 0 | 6659 | 2219 |
| ENST00000354520 | KMT2A | chr11 | 118355029 | + | ENST00000378595 | AFF4 | chr5 | 132240096 | - | 6152 | 4218 | 0 | 5870 | 1956 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
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Fusion Genomic Features for KMT2A-AFF4 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for KMT2A-AFF4 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:/chr5:) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| KMT2A | AFF4 |
| FUNCTION: Histone methyltransferase that plays an essential role in early development and hematopoiesis (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac) (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:24235145, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. Part of chromatin remodeling machinery predominantly forms H3K4me1 and H3K4me2 methylation marks at active chromatin sites where transcription and DNA repair take place (PubMed:25561738, PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity (PubMed:19187761, PubMed:26886794). Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9' (PubMed:19187761). Binds to unmethylated CpG elements in the promoter of target genes and helps maintain them in the nonmethylated state (PubMed:20010842). Required for transcriptional activation of HOXA9 (PubMed:12453419, PubMed:20677832, PubMed:20010842). Promotes PPP1R15A-induced apoptosis (PubMed:10490642). Plays a critical role in the control of circadian gene expression and is essential for the transcriptional activation mediated by the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Establishes a permissive chromatin state for circadian transcription by mediating a rhythmic methylation of 'Lys-4' of histone H3 (H3K4me) and this histone modification directs the circadian acetylation at H3K9 and H3K14 allowing the recruitment of CLOCK-ARNTL/BMAL1 to chromatin (By similarity). Also has auto-methylation activity on Cys-3882 in absence of histone H3 substrate (PubMed:24235145). {ECO:0000250|UniProtKB:P55200, ECO:0000269|PubMed:10490642, ECO:0000269|PubMed:12453419, ECO:0000269|PubMed:15960975, ECO:0000269|PubMed:19187761, ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:20010842, ECO:0000269|PubMed:21220120, ECO:0000269|PubMed:24235145, ECO:0000269|PubMed:26886794, ECO:0000305|PubMed:20677832}. | FUNCTION: Key component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. In the SEC complex, AFF4 acts as a central scaffold that recruits other factors through direct interactions with ELL proteins (ELL, ELL2 or ELL3) and the P-TEFb complex. In case of infection by HIV-1 virus, the SEC complex is recruited by the viral Tat protein to stimulate viral gene expression. {ECO:0000269|PubMed:20159561, ECO:0000269|PubMed:20471948, ECO:0000269|PubMed:23251033}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
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Fusion Gene Sequence for KMT2A-AFF4 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >43140_43140_1_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000354520_AFF4_chr5_132240096_ENST00000265343_length(transcript)=12208nt_BP=4086nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCT AAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGT GATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCT AGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAG AGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCC GCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACA AGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAA TCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCT CGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCA AGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAG AAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTAC CCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAG AAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGA AAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAA AAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAAT TCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCT GTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAAC AAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTT AAGGAAAAGGCTCCAAGTAGCTCCTCTAACTGTCCTCCATCTGCACCAACTCTTGATTCTTCTAAGCCTCGGAGAACAAAGCTTGTCTTT GATGACAGAAATTATTCAGCAGACCATTATTTACAAGAAGCAAAAAAGCTAAAGCACAATGCAGATGCATTGTCTGATAGGTTTGAGAAA GCTGTATACTATCTTGATGCTGTGGTATCTTTCATTGAATGTGGGAATGCATTAGAGAAGAATGCTCAGGAATCCAAATCCCCATTCCCT ATGTATTCAGAGACGGTGGATCTCATCAAATACACTATGAAGCTAAAGAATTACTTGGCACCAGATGCTACAGCTGCAGATAAACGACTC ACAGTACTTTGCCTGCGATGCGAGTCTTTGCTGTACCTGAGGCTGTTCAAACTGAAGAAGGAAAATGCTCTGAAGTACTCAAAGACACTG ACAGAGCACCTGAAGAATTCTTATAATAATTCTCAAGCACCATCGCCTGGCTTGGGAAGCAAAGCTGTGGGGATGCCTTCCCCTGTTTCT CCAAAGCTGTCACCAGGCAATTCAGGAAATTATTCATCTGGGGCCAGTAGTGCTTCTGCAAGTGGTTCTTCAGTGACCATTCCACAGAAG ATCCACCAGATGGCAGCCAGCTATGTTCAGGTCACATCCAACTTCCTCTATGCCACCGAAATTTGGGACCAAGCTGAACAGCTTTCCAAA GAGCAAAAAGAATTCTTTGCTGAACTGGATAAAGTAATGGGCCCTCTCATCTTTAATGCAAGCATCATGACAGATCTAGTTCGTTATACC CGGCAGGGACTGCACTGGCTTCGCCAGGATGCCAAGTTGATATCTTGAACTGAACACATTCTCGTTGCCTCTGATTTTCTCCACAACACT GTGTCACATCACGAAGGAAAACTGCCATAACATACCACCTAGTCGACACTAAGAATGAGGAATAGTTTTCTCCTCGTTGGTTCATGTGTT GTTGTTTTTGATAATCCAAAGCGATCATGTCAGTTGGCCCTTTAATATTTCCAATGTGAAAGATTATTTAAATGCTTTTAAATCTGCAGC ACATTGATAAGATGGTTTCCGTGAGCTATGATAAGATTGAAATTCCAGTTGCAATTCATAACTAATGAATTGAAATTTTATTTATTTTAA TTTTTTTAAGTTCCCAGATTGGGGCTAGTTTAAGACTTAGTTATTTCTGCCTATAAATTTACTCTGTTGAATATTTAGCATAAATTTAAT GTAGACATTTTTATTTATATACCTTGGGAGCTTTATTACCTAATATCTTTTTGTGGTAGCTGTTCTAAGAGTAAGAATTGGTTCGTCTAA AATAAGGACATATTCTTTCTACACCTGCTACCTGACCTGATATTTGAAATCTTAACTCCAATTTTATTATTGTGGAATTTACAGTTAGTA TTAAGGATATTCTTCTACACATGAAAAAATCACTTAAATATGAGAAAATGGCATTCTACATGTATGTACTATGAAATGTGTCTGATTTGG TATGCATTATTTCAAAAACTGTGAATGTGTGTTAATAACACTACAGCAATCACACAGTGACTATAGCTTGCATTTAATGCATTACAAAAG AGGGAGGACAAACTTTCTAGAAGAAGCATTTCATGTTGAAGGGTTTCATAAAAGGACAATCCTGAACGTTACGGATTTTATTAAAACCAT ATGTTATTTTTTGTTGCTAATCATTTGACACTTAATCGAAACAGAATAAGTTACTGTGGAAAAAAGGATGATCCAACTCCTGAGGATTGC CGCCTGTGTGTCTTTAATTGATTATCTTTGATAGTTAGAGTTATTTTTCAGATTTTTCCCCCTCATACTGGATTGTGATGCTCTGATATG AGCATGCAATGACTGATACAGAAATAGGCTGGAGCTTCGGTGTGTGCTTTTGCTATACAGCTTACAGTTCTAATGCCTGATGTAGAGATG ATGAATTTCTCCTTTTTAAACCTATCTTCTGTTTACTCCTTTTGCATTATGAAGGCCCTCTTCAATGATGTATGTTTCTGATGGAATCAG AAAATTTCACACTAGAAAAGTGTACCTAACTTGATTCAGTGTGAGCTCTTGGGACAGGGAGTGGAGCCAGGGGTAGAGCTTAAAGAAGCT GGCTCTGTAAGAGTTGTATATCAAAGTACCTTTTGCTACAAGGTGCATATAGAAGTCTAAGATAAGAAATGTACCCTCTATACTTTATTT TTCATGCCCCTATCATGTTTGGTGTGCCTTAAATCTTACCTTTAAATGAAGACTCTATGGATTGTTTACAAATGAAGTTTTACACTAGGA CCAGATCGTCCATACATGATTGGTCTTCTACAATAATAATGTTCAATTCTTTCATTTTAAATCTTTCTTTAGGGTCATATAAAGATTAGT TCTTTCAGAAAAGCTATTGCTTTGGTACATGACTTAGTCTAACCAGTTGGGTAATGCTGCTTTGAAAAATAGTTTGTCCCTCTCCCCATT CCAAAAATGAATCCATTCAGTCAGAAAAAAAGATTATCCTACTATTTGTAGATGATTGCTAAGGCTTGAAATAGGAAAGGGGAAAGAAGG GATAGAAAAGTTTCAAGTCCAGTAGTGCAGTGAATCCTTTGTGTTTGAGACTTTTTTACACTTATTTCTGAAGTTAGTGAACTTTCATTG TCCCTGTGGCCTCATATTTATAGAGCTTCTTAACTGTTTTGTACCTCAGATTGTTTTTAGATGTCATTGAAGATTGAGATGTACAAATTA TGTTGAATTTAACCTGTTTCTCTTGGAGAAATTGCCTCTGATATCTTTCTAACTTAATCTTAGTGTGTTCTAGGAACAGTTTTCCATAAG AGGACAACTTCTCAATGATCATGATAGTTATTTAGTAAGAAATAATGGTTGTTAATCAAATACATGTTATGTCTTGTCCTTCTCTGATTT TTCTGACTTGGATTCCTTAATTTGCAGTGATGTCTTAGAAATGGAAAAAGTATCCTCTGGGCTTTCAGACTTTCAGCAACAACAGCCAGT GGGATACCTCTGAGTTCTTGTGTTCTAGTCTCTTGTATGTCCTGAAAGGCAGCAGGAGCATTTTTGGGGTCACACTGATATTTTGTTAAA GCAGAGTTTCCTGCATGGTTTATGGTGCTGCTCTAATATTTTCTCTTTAAAACTGTGTCAATTTTTGGAGAATGAATTTTTCAACCTTTT CATTGTGGAGGATTTTTCCCACAAGGTAGTAATGGGCAATGGATCAAAATCCTATCATAAATGATTGAATTTTCAATGTCATAGTGTGTG GAAATACTACTCCCTTTCCTCCATGTCTATCTTCTTAGATGTTCTGTCTTTGTCATCATCTGCTCCAGCACATACTTTGGACTCCTTTAC AGGTGACCTTCCCCCCTCCCTCCTCAATAGGTGTCCTCAGTGTTTTCTAAGCATTTAAAACTGAATTTGACAAGTGGCTAAAAACTTAGT CTGAGACTTGTACTTAGTATATGGTTAATTATAGAAACAACAACTATTTTAAACAGTTACTCTGTTGACTGCTCTTTATGACTACACTTG TATGCCAGGAGGCAGCAGCCTATACACCATTAGACTCTTTACAAGCAACCAACGAACCAATTGCAGTGGTTGCAGTTGTCACAGTAGTCT TGCCTGGGCCAGACTGGGCTGGGCTGTGGGAAGCATTCCCCTTCAGGGGAGTTTCCACAGCTCAGCCCAGGCTCCAGTCTGGCTAGAGAG CATCCAGCCCATTCCTTGCCTCAGTGCCACCTTTTTCTGGGCAAGTAGCCAAGAAGTGACTTTATATGCAGTGAGTACTTCAGATAAACT TACAGCTACAGCTGCCGAAGAGTGGAGAAGGTTGACCACCATTTATTTAATTCTCTAGTGTAAAAACAATTGAGAGCAGTGTGCGTGAGC CCACAGACACCTGTGTTTCTGGGAGCTCTGGCAGTGGCGGATTCATAGGCACTTGGGCTGCACTTTGAATGACACACTTGGCTTTATTAG ATTCACTAGTTTTTAAAAAATTGTTGTTCGTTTCTTTTCATTAAAGGTTTAATCAGACAGATCAGACAGCATAATTTTGTATTTAATGAC AGAAACGTTGGTACATTTCTTCATGAATGAGCTTGCATTCTGAAGCAAGAGCCTACAAAAGGCACTTGTTATAAATGAAAGTTCTGGCTC TAGAGGCCAGTACTCTGGAGTTTCAGAGCAGCCAGTGATTGTTCCAGTCAGTGATGCCTAGTTATATAGAGGAGGAGTACACTGTGCACT CTTCTAGGTGTAAGGGTATGCAACTTTGGATCTTAAAATTCTGTACACATACACACTTTATATATATGTATGTATGTATGAAAACATGAA ATTAGTTTGTCAAATATGTGTGTGTTTAGTATTTTAGCTTAGTGCAACTATTTCCACATTATTTATTAAATTGATCTAAGACACTTTCTT GTTGACACCTTGAATATTAATGTTCAAGGGTGCAATGTGTATTCCTTTAGATTGTTAAAGCTTAATTACTATGATTTGTAGTAAATTAAC TTTTAAAATGTATTTGAGCCCTTCTGTAGTGTCGTAGGGCTCTTACAGGGTGGGAAAGATTTTAATTTTCCAGTTGCTAATTGAACAGTA TGGCCTCATTATATATTTTGATTTATAGGAGTTTGTGTCTGGGTCCCAGGAACATCTACTGGGGATGACTGTTAGGCAGCTTGTGATGAT GTTTTTTAAAAAACCTAAGTAACTTGGGGAGACAGAGCATTTCAAACCCATATAGACACCTATCATACCTGTATATCCCCTAATACATGG AACATAAATTTCATTTCAGCTTTATGCATTAATGTATTGAAGAGGCAGGCTTTTTTTCCAGTAATAATACTGTACATCTAAGGTTGCTAT TCAGTAAAACTAATAGAAGAGATAATTATTGAATACCTTGGAATATGTAGTGAGAAGAGGCCAAATTTTTCATGTTTGTGAGCATGTCTT TCAGATACTCGCTAATGGAGAAATTCACTTTAGACCTCTAGACCCCAAAACCAAGTTAGCAAGTGACAAAAAGTAAATTATTAATAGTCT GTAAAGTGGATGCTGGTCTTACAAAGCTCCTATTCACATGAACCCTATGGTTAATTAGAAAGAACTTGCTGTCTCCAGAAAAGGGAATGG AAATAATAACTATGTATCTTCTTTTCATGTAATTTGGTCACAGAATAAGGTATTCAAGTTAAGTCTAATCCAAGTCTTAGAGATCTTTAA GTATCCTAAAATAGCAGCCTAAGTAGTCATCATGTAAAGAAGTTGACTTTCAGGAATGTCAGCATTGACCTCTCCTTGCCACTGTTACTC AGCTAAACATAACTTGCCATTCTTAAAAATAAAAAAGCTCCCACCCAGAAACTCTAGTGATACTCAGTTTTGACCTCTTACTGCTTCCAT GTGGGACTTCTTTTCAGCTTTTAACCATTGGAATTTTCTACCTGCTATGTTCCTCTCTGGAAAATATCAATTTGGAAATGCTGCCTTTCA AATCAATGCCATGATCATCCATATTGTTGAGTTTGTTGTTGGTGTTCCAGAAGTGTCCCCATTTTACAACTTTATGCACACACCTGGCAA ATCATTAACATGAGCATTCAACAGTACTGGGATGGGTGGGGTGGGGGTAGGGGGCTCACCAACAGAACTGGCCAGTTGACATTGCCTGAA AAGGCACCACCTTTAAGGGCCAGTTGTGGGGTTGGTAAGCACAGTTATGAAAATTTCTATCTAGCCTCCGTTTTGAATGGTTTTAAGAAA TTTTGTATATGGAGGATGGAAATGCTTATATATTTATTGAAAATCCTTTTATTTGAAATTAAAATTATTTGGTATATAATTGTTTGATAT TTGGGGAGGGTTTTGGAGGGGAGATAATGTCACTGATAAATTAAAAGCCTGTTGATTTTGCAGAAAGGTACTGTTAGTGACTGATAAGGA TGCCTTTGTTTTGTACATGAACCAAATCTTTGTTTTACATTTCTTTTATCCAAAATATTTAGGCATCTGACATTTTCAACCAGAATTTCA ATTATATACTGTGATTTTTATTTGTTGCAATACATTACAATTTCAGAGGTACTTTGGGGCTCAAAAGCTAGGATTTCTAAGTCAGTATGT GCATTTCACACGATAAAGCTGTTAATGGTGAGCAAAGTATTATATACTAACTAGATTTTTCCACATCTGTATAGTATATTATATGTATTT TGTGGTATTGAGAGTATAGAAAGTTTAGAGTGTCAAACATGCGTTTAATGTGTATTTTTAAACAAATTTATGGCAATTAAAATATTTGGA GACAAGGGTATCACATTTCAATTTGTAAAGATCTTTTTAACTCTACTGTGTCATTAAGATGCTTTGTACAATGCCAAACCATAGTTGGAG >43140_43140_1_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000354520_AFF4_chr5_132240096_ENST00000265343_length(amino acids)=2175AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDS SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDT SGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS RKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEE KELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKN SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV KEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFP MYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVS PKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLVRYT -------------------------------------------------------------- >43140_43140_2_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000354520_AFF4_chr5_132240096_ENST00000378595_length(transcript)=6020nt_BP=4086nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCT AAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGT GATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCT AGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAG AGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCC GCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACA AGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAA TCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCT CGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCA AGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAG AAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTAC CCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAG AAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGA AAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAA AAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAAT TCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCT GTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAAC AAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTT AAGGTAAAGTGTTGGGGGCCTGGGGCTTTTGAAAATCATTCAACTTGCCATGTGACTTTTCCAGGGTGACACTGTGCTTTGAAATTATTG TAACATCTCAGTAAATATATAGGCCTATGTCTTTTACCCTCTATATGTAATAATCCTGATAAATGAATACAGTGATATAAGACTGTGAAG GTGGTAAGTCAGCTGGTCACATACATATTGAAAGAAAAACCCTTGGGTACAGTGGCTCATACCTGTAGTCCCAGCTATTTGGGAGGCTAA >43140_43140_2_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000354520_AFF4_chr5_132240096_ENST00000378595_length(amino acids)=1912AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDS SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDT SGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS RKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEE KELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKN SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV -------------------------------------------------------------- >43140_43140_3_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000354520_AFF4_chr5_132262899_ENST00000265343_length(transcript)=12295nt_BP=4086nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACGCATTCATGGCCTCCCCCTCTAACGGCTATTCATACACCATGCAAA ACAGAACCTTCCAAATTTCCTTTTCCAACTAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAA ACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGAT AAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGT AGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGT GCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCC TCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGT GGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCT CCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGT GGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGG AAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAA TCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCC GAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAG GAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAG CCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAA GTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCA GCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTT CCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAG GAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAG GAAAAGGCTCCAAGTAGCTCCTCTAACTGTCCTCCATCTGCACCAACTCTTGATTCTTCTAAGCCTCGGAGAACAAAGCTTGTCTTTGAT GACAGAAATTATTCAGCAGACCATTATTTACAAGAAGCAAAAAAGCTAAAGCACAATGCAGATGCATTGTCTGATAGGTTTGAGAAAGCT GTATACTATCTTGATGCTGTGGTATCTTTCATTGAATGTGGGAATGCATTAGAGAAGAATGCTCAGGAATCCAAATCCCCATTCCCTATG TATTCAGAGACGGTGGATCTCATCAAATACACTATGAAGCTAAAGAATTACTTGGCACCAGATGCTACAGCTGCAGATAAACGACTCACA GTACTTTGCCTGCGATGCGAGTCTTTGCTGTACCTGAGGCTGTTCAAACTGAAGAAGGAAAATGCTCTGAAGTACTCAAAGACACTGACA GAGCACCTGAAGAATTCTTATAATAATTCTCAAGCACCATCGCCTGGCTTGGGAAGCAAAGCTGTGGGGATGCCTTCCCCTGTTTCTCCA AAGCTGTCACCAGGCAATTCAGGAAATTATTCATCTGGGGCCAGTAGTGCTTCTGCAAGTGGTTCTTCAGTGACCATTCCACAGAAGATC CACCAGATGGCAGCCAGCTATGTTCAGGTCACATCCAACTTCCTCTATGCCACCGAAATTTGGGACCAAGCTGAACAGCTTTCCAAAGAG CAAAAAGAATTCTTTGCTGAACTGGATAAAGTAATGGGCCCTCTCATCTTTAATGCAAGCATCATGACAGATCTAGTTCGTTATACCCGG CAGGGACTGCACTGGCTTCGCCAGGATGCCAAGTTGATATCTTGAACTGAACACATTCTCGTTGCCTCTGATTTTCTCCACAACACTGTG TCACATCACGAAGGAAAACTGCCATAACATACCACCTAGTCGACACTAAGAATGAGGAATAGTTTTCTCCTCGTTGGTTCATGTGTTGTT GTTTTTGATAATCCAAAGCGATCATGTCAGTTGGCCCTTTAATATTTCCAATGTGAAAGATTATTTAAATGCTTTTAAATCTGCAGCACA TTGATAAGATGGTTTCCGTGAGCTATGATAAGATTGAAATTCCAGTTGCAATTCATAACTAATGAATTGAAATTTTATTTATTTTAATTT TTTTAAGTTCCCAGATTGGGGCTAGTTTAAGACTTAGTTATTTCTGCCTATAAATTTACTCTGTTGAATATTTAGCATAAATTTAATGTA GACATTTTTATTTATATACCTTGGGAGCTTTATTACCTAATATCTTTTTGTGGTAGCTGTTCTAAGAGTAAGAATTGGTTCGTCTAAAAT AAGGACATATTCTTTCTACACCTGCTACCTGACCTGATATTTGAAATCTTAACTCCAATTTTATTATTGTGGAATTTACAGTTAGTATTA AGGATATTCTTCTACACATGAAAAAATCACTTAAATATGAGAAAATGGCATTCTACATGTATGTACTATGAAATGTGTCTGATTTGGTAT GCATTATTTCAAAAACTGTGAATGTGTGTTAATAACACTACAGCAATCACACAGTGACTATAGCTTGCATTTAATGCATTACAAAAGAGG GAGGACAAACTTTCTAGAAGAAGCATTTCATGTTGAAGGGTTTCATAAAAGGACAATCCTGAACGTTACGGATTTTATTAAAACCATATG TTATTTTTTGTTGCTAATCATTTGACACTTAATCGAAACAGAATAAGTTACTGTGGAAAAAAGGATGATCCAACTCCTGAGGATTGCCGC CTGTGTGTCTTTAATTGATTATCTTTGATAGTTAGAGTTATTTTTCAGATTTTTCCCCCTCATACTGGATTGTGATGCTCTGATATGAGC ATGCAATGACTGATACAGAAATAGGCTGGAGCTTCGGTGTGTGCTTTTGCTATACAGCTTACAGTTCTAATGCCTGATGTAGAGATGATG AATTTCTCCTTTTTAAACCTATCTTCTGTTTACTCCTTTTGCATTATGAAGGCCCTCTTCAATGATGTATGTTTCTGATGGAATCAGAAA ATTTCACACTAGAAAAGTGTACCTAACTTGATTCAGTGTGAGCTCTTGGGACAGGGAGTGGAGCCAGGGGTAGAGCTTAAAGAAGCTGGC TCTGTAAGAGTTGTATATCAAAGTACCTTTTGCTACAAGGTGCATATAGAAGTCTAAGATAAGAAATGTACCCTCTATACTTTATTTTTC ATGCCCCTATCATGTTTGGTGTGCCTTAAATCTTACCTTTAAATGAAGACTCTATGGATTGTTTACAAATGAAGTTTTACACTAGGACCA GATCGTCCATACATGATTGGTCTTCTACAATAATAATGTTCAATTCTTTCATTTTAAATCTTTCTTTAGGGTCATATAAAGATTAGTTCT TTCAGAAAAGCTATTGCTTTGGTACATGACTTAGTCTAACCAGTTGGGTAATGCTGCTTTGAAAAATAGTTTGTCCCTCTCCCCATTCCA AAAATGAATCCATTCAGTCAGAAAAAAAGATTATCCTACTATTTGTAGATGATTGCTAAGGCTTGAAATAGGAAAGGGGAAAGAAGGGAT AGAAAAGTTTCAAGTCCAGTAGTGCAGTGAATCCTTTGTGTTTGAGACTTTTTTACACTTATTTCTGAAGTTAGTGAACTTTCATTGTCC CTGTGGCCTCATATTTATAGAGCTTCTTAACTGTTTTGTACCTCAGATTGTTTTTAGATGTCATTGAAGATTGAGATGTACAAATTATGT TGAATTTAACCTGTTTCTCTTGGAGAAATTGCCTCTGATATCTTTCTAACTTAATCTTAGTGTGTTCTAGGAACAGTTTTCCATAAGAGG ACAACTTCTCAATGATCATGATAGTTATTTAGTAAGAAATAATGGTTGTTAATCAAATACATGTTATGTCTTGTCCTTCTCTGATTTTTC TGACTTGGATTCCTTAATTTGCAGTGATGTCTTAGAAATGGAAAAAGTATCCTCTGGGCTTTCAGACTTTCAGCAACAACAGCCAGTGGG ATACCTCTGAGTTCTTGTGTTCTAGTCTCTTGTATGTCCTGAAAGGCAGCAGGAGCATTTTTGGGGTCACACTGATATTTTGTTAAAGCA GAGTTTCCTGCATGGTTTATGGTGCTGCTCTAATATTTTCTCTTTAAAACTGTGTCAATTTTTGGAGAATGAATTTTTCAACCTTTTCAT TGTGGAGGATTTTTCCCACAAGGTAGTAATGGGCAATGGATCAAAATCCTATCATAAATGATTGAATTTTCAATGTCATAGTGTGTGGAA ATACTACTCCCTTTCCTCCATGTCTATCTTCTTAGATGTTCTGTCTTTGTCATCATCTGCTCCAGCACATACTTTGGACTCCTTTACAGG TGACCTTCCCCCCTCCCTCCTCAATAGGTGTCCTCAGTGTTTTCTAAGCATTTAAAACTGAATTTGACAAGTGGCTAAAAACTTAGTCTG AGACTTGTACTTAGTATATGGTTAATTATAGAAACAACAACTATTTTAAACAGTTACTCTGTTGACTGCTCTTTATGACTACACTTGTAT GCCAGGAGGCAGCAGCCTATACACCATTAGACTCTTTACAAGCAACCAACGAACCAATTGCAGTGGTTGCAGTTGTCACAGTAGTCTTGC CTGGGCCAGACTGGGCTGGGCTGTGGGAAGCATTCCCCTTCAGGGGAGTTTCCACAGCTCAGCCCAGGCTCCAGTCTGGCTAGAGAGCAT CCAGCCCATTCCTTGCCTCAGTGCCACCTTTTTCTGGGCAAGTAGCCAAGAAGTGACTTTATATGCAGTGAGTACTTCAGATAAACTTAC AGCTACAGCTGCCGAAGAGTGGAGAAGGTTGACCACCATTTATTTAATTCTCTAGTGTAAAAACAATTGAGAGCAGTGTGCGTGAGCCCA CAGACACCTGTGTTTCTGGGAGCTCTGGCAGTGGCGGATTCATAGGCACTTGGGCTGCACTTTGAATGACACACTTGGCTTTATTAGATT CACTAGTTTTTAAAAAATTGTTGTTCGTTTCTTTTCATTAAAGGTTTAATCAGACAGATCAGACAGCATAATTTTGTATTTAATGACAGA AACGTTGGTACATTTCTTCATGAATGAGCTTGCATTCTGAAGCAAGAGCCTACAAAAGGCACTTGTTATAAATGAAAGTTCTGGCTCTAG AGGCCAGTACTCTGGAGTTTCAGAGCAGCCAGTGATTGTTCCAGTCAGTGATGCCTAGTTATATAGAGGAGGAGTACACTGTGCACTCTT CTAGGTGTAAGGGTATGCAACTTTGGATCTTAAAATTCTGTACACATACACACTTTATATATATGTATGTATGTATGAAAACATGAAATT AGTTTGTCAAATATGTGTGTGTTTAGTATTTTAGCTTAGTGCAACTATTTCCACATTATTTATTAAATTGATCTAAGACACTTTCTTGTT GACACCTTGAATATTAATGTTCAAGGGTGCAATGTGTATTCCTTTAGATTGTTAAAGCTTAATTACTATGATTTGTAGTAAATTAACTTT TAAAATGTATTTGAGCCCTTCTGTAGTGTCGTAGGGCTCTTACAGGGTGGGAAAGATTTTAATTTTCCAGTTGCTAATTGAACAGTATGG CCTCATTATATATTTTGATTTATAGGAGTTTGTGTCTGGGTCCCAGGAACATCTACTGGGGATGACTGTTAGGCAGCTTGTGATGATGTT TTTTAAAAAACCTAAGTAACTTGGGGAGACAGAGCATTTCAAACCCATATAGACACCTATCATACCTGTATATCCCCTAATACATGGAAC ATAAATTTCATTTCAGCTTTATGCATTAATGTATTGAAGAGGCAGGCTTTTTTTCCAGTAATAATACTGTACATCTAAGGTTGCTATTCA GTAAAACTAATAGAAGAGATAATTATTGAATACCTTGGAATATGTAGTGAGAAGAGGCCAAATTTTTCATGTTTGTGAGCATGTCTTTCA GATACTCGCTAATGGAGAAATTCACTTTAGACCTCTAGACCCCAAAACCAAGTTAGCAAGTGACAAAAAGTAAATTATTAATAGTCTGTA AAGTGGATGCTGGTCTTACAAAGCTCCTATTCACATGAACCCTATGGTTAATTAGAAAGAACTTGCTGTCTCCAGAAAAGGGAATGGAAA TAATAACTATGTATCTTCTTTTCATGTAATTTGGTCACAGAATAAGGTATTCAAGTTAAGTCTAATCCAAGTCTTAGAGATCTTTAAGTA TCCTAAAATAGCAGCCTAAGTAGTCATCATGTAAAGAAGTTGACTTTCAGGAATGTCAGCATTGACCTCTCCTTGCCACTGTTACTCAGC TAAACATAACTTGCCATTCTTAAAAATAAAAAAGCTCCCACCCAGAAACTCTAGTGATACTCAGTTTTGACCTCTTACTGCTTCCATGTG GGACTTCTTTTCAGCTTTTAACCATTGGAATTTTCTACCTGCTATGTTCCTCTCTGGAAAATATCAATTTGGAAATGCTGCCTTTCAAAT CAATGCCATGATCATCCATATTGTTGAGTTTGTTGTTGGTGTTCCAGAAGTGTCCCCATTTTACAACTTTATGCACACACCTGGCAAATC ATTAACATGAGCATTCAACAGTACTGGGATGGGTGGGGTGGGGGTAGGGGGCTCACCAACAGAACTGGCCAGTTGACATTGCCTGAAAAG GCACCACCTTTAAGGGCCAGTTGTGGGGTTGGTAAGCACAGTTATGAAAATTTCTATCTAGCCTCCGTTTTGAATGGTTTTAAGAAATTT TGTATATGGAGGATGGAAATGCTTATATATTTATTGAAAATCCTTTTATTTGAAATTAAAATTATTTGGTATATAATTGTTTGATATTTG GGGAGGGTTTTGGAGGGGAGATAATGTCACTGATAAATTAAAAGCCTGTTGATTTTGCAGAAAGGTACTGTTAGTGACTGATAAGGATGC CTTTGTTTTGTACATGAACCAAATCTTTGTTTTACATTTCTTTTATCCAAAATATTTAGGCATCTGACATTTTCAACCAGAATTTCAATT ATATACTGTGATTTTTATTTGTTGCAATACATTACAATTTCAGAGGTACTTTGGGGCTCAAAAGCTAGGATTTCTAAGTCAGTATGTGCA TTTCACACGATAAAGCTGTTAATGGTGAGCAAAGTATTATATACTAACTAGATTTTTCCACATCTGTATAGTATATTATATGTATTTTGT GGTATTGAGAGTATAGAAAGTTTAGAGTGTCAAACATGCGTTTAATGTGTATTTTTAAACAAATTTATGGCAATTAAAATATTTGGAGAC AAGGGTATCACATTTCAATTTGTAAAGATCTTTTTAACTCTACTGTGTCATTAAGATGCTTTGTACAATGCCAAACCATAGTTGGAGAAA >43140_43140_3_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000354520_AFF4_chr5_132262899_ENST00000265343_length(amino acids)=2204AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCD KTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPA SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPR GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYP ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEK VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNK ETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKA VYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLT EHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKE -------------------------------------------------------------- >43140_43140_4_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000354520_AFF4_chr5_132262899_ENST00000378595_length(transcript)=6107nt_BP=4086nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACGCATTCATGGCCTCCCCCTCTAACGGCTATTCATACACCATGCAAA ACAGAACCTTCCAAATTTCCTTTTCCAACTAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAA ACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGAT AAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGT AGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGT GCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCC TCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGT GGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCT CCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGT GGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGG AAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAA TCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCC GAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAG GAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAG CCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAA GTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCA GCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTT CCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAG GAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAG GTAAAGTGTTGGGGGCCTGGGGCTTTTGAAAATCATTCAACTTGCCATGTGACTTTTCCAGGGTGACACTGTGCTTTGAAATTATTGTAA CATCTCAGTAAATATATAGGCCTATGTCTTTTACCCTCTATATGTAATAATCCTGATAAATGAATACAGTGATATAAGACTGTGAAGGTG GTAAGTCAGCTGGTCACATACATATTGAAAGAAAAACCCTTGGGTACAGTGGCTCATACCTGTAGTCCCAGCTATTTGGGAGGCTAAGAT >43140_43140_4_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000354520_AFF4_chr5_132262899_ENST00000378595_length(amino acids)=1941AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCD KTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPA SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPR GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYP ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEK VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNK -------------------------------------------------------------- >43140_43140_5_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000389506_AFF4_chr5_132240096_ENST00000265343_length(transcript)=12208nt_BP=4086nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCT AAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGT GATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCT AGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAG AGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCC GCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACA AGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAA TCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCT CGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCA AGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAG AAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTAC CCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAG AAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGA AAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAA AAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAAT TCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCT GTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAAC AAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTT AAGGAAAAGGCTCCAAGTAGCTCCTCTAACTGTCCTCCATCTGCACCAACTCTTGATTCTTCTAAGCCTCGGAGAACAAAGCTTGTCTTT GATGACAGAAATTATTCAGCAGACCATTATTTACAAGAAGCAAAAAAGCTAAAGCACAATGCAGATGCATTGTCTGATAGGTTTGAGAAA GCTGTATACTATCTTGATGCTGTGGTATCTTTCATTGAATGTGGGAATGCATTAGAGAAGAATGCTCAGGAATCCAAATCCCCATTCCCT ATGTATTCAGAGACGGTGGATCTCATCAAATACACTATGAAGCTAAAGAATTACTTGGCACCAGATGCTACAGCTGCAGATAAACGACTC ACAGTACTTTGCCTGCGATGCGAGTCTTTGCTGTACCTGAGGCTGTTCAAACTGAAGAAGGAAAATGCTCTGAAGTACTCAAAGACACTG ACAGAGCACCTGAAGAATTCTTATAATAATTCTCAAGCACCATCGCCTGGCTTGGGAAGCAAAGCTGTGGGGATGCCTTCCCCTGTTTCT CCAAAGCTGTCACCAGGCAATTCAGGAAATTATTCATCTGGGGCCAGTAGTGCTTCTGCAAGTGGTTCTTCAGTGACCATTCCACAGAAG ATCCACCAGATGGCAGCCAGCTATGTTCAGGTCACATCCAACTTCCTCTATGCCACCGAAATTTGGGACCAAGCTGAACAGCTTTCCAAA GAGCAAAAAGAATTCTTTGCTGAACTGGATAAAGTAATGGGCCCTCTCATCTTTAATGCAAGCATCATGACAGATCTAGTTCGTTATACC CGGCAGGGACTGCACTGGCTTCGCCAGGATGCCAAGTTGATATCTTGAACTGAACACATTCTCGTTGCCTCTGATTTTCTCCACAACACT GTGTCACATCACGAAGGAAAACTGCCATAACATACCACCTAGTCGACACTAAGAATGAGGAATAGTTTTCTCCTCGTTGGTTCATGTGTT GTTGTTTTTGATAATCCAAAGCGATCATGTCAGTTGGCCCTTTAATATTTCCAATGTGAAAGATTATTTAAATGCTTTTAAATCTGCAGC ACATTGATAAGATGGTTTCCGTGAGCTATGATAAGATTGAAATTCCAGTTGCAATTCATAACTAATGAATTGAAATTTTATTTATTTTAA TTTTTTTAAGTTCCCAGATTGGGGCTAGTTTAAGACTTAGTTATTTCTGCCTATAAATTTACTCTGTTGAATATTTAGCATAAATTTAAT GTAGACATTTTTATTTATATACCTTGGGAGCTTTATTACCTAATATCTTTTTGTGGTAGCTGTTCTAAGAGTAAGAATTGGTTCGTCTAA AATAAGGACATATTCTTTCTACACCTGCTACCTGACCTGATATTTGAAATCTTAACTCCAATTTTATTATTGTGGAATTTACAGTTAGTA TTAAGGATATTCTTCTACACATGAAAAAATCACTTAAATATGAGAAAATGGCATTCTACATGTATGTACTATGAAATGTGTCTGATTTGG TATGCATTATTTCAAAAACTGTGAATGTGTGTTAATAACACTACAGCAATCACACAGTGACTATAGCTTGCATTTAATGCATTACAAAAG AGGGAGGACAAACTTTCTAGAAGAAGCATTTCATGTTGAAGGGTTTCATAAAAGGACAATCCTGAACGTTACGGATTTTATTAAAACCAT ATGTTATTTTTTGTTGCTAATCATTTGACACTTAATCGAAACAGAATAAGTTACTGTGGAAAAAAGGATGATCCAACTCCTGAGGATTGC CGCCTGTGTGTCTTTAATTGATTATCTTTGATAGTTAGAGTTATTTTTCAGATTTTTCCCCCTCATACTGGATTGTGATGCTCTGATATG AGCATGCAATGACTGATACAGAAATAGGCTGGAGCTTCGGTGTGTGCTTTTGCTATACAGCTTACAGTTCTAATGCCTGATGTAGAGATG ATGAATTTCTCCTTTTTAAACCTATCTTCTGTTTACTCCTTTTGCATTATGAAGGCCCTCTTCAATGATGTATGTTTCTGATGGAATCAG AAAATTTCACACTAGAAAAGTGTACCTAACTTGATTCAGTGTGAGCTCTTGGGACAGGGAGTGGAGCCAGGGGTAGAGCTTAAAGAAGCT GGCTCTGTAAGAGTTGTATATCAAAGTACCTTTTGCTACAAGGTGCATATAGAAGTCTAAGATAAGAAATGTACCCTCTATACTTTATTT TTCATGCCCCTATCATGTTTGGTGTGCCTTAAATCTTACCTTTAAATGAAGACTCTATGGATTGTTTACAAATGAAGTTTTACACTAGGA CCAGATCGTCCATACATGATTGGTCTTCTACAATAATAATGTTCAATTCTTTCATTTTAAATCTTTCTTTAGGGTCATATAAAGATTAGT TCTTTCAGAAAAGCTATTGCTTTGGTACATGACTTAGTCTAACCAGTTGGGTAATGCTGCTTTGAAAAATAGTTTGTCCCTCTCCCCATT CCAAAAATGAATCCATTCAGTCAGAAAAAAAGATTATCCTACTATTTGTAGATGATTGCTAAGGCTTGAAATAGGAAAGGGGAAAGAAGG GATAGAAAAGTTTCAAGTCCAGTAGTGCAGTGAATCCTTTGTGTTTGAGACTTTTTTACACTTATTTCTGAAGTTAGTGAACTTTCATTG TCCCTGTGGCCTCATATTTATAGAGCTTCTTAACTGTTTTGTACCTCAGATTGTTTTTAGATGTCATTGAAGATTGAGATGTACAAATTA TGTTGAATTTAACCTGTTTCTCTTGGAGAAATTGCCTCTGATATCTTTCTAACTTAATCTTAGTGTGTTCTAGGAACAGTTTTCCATAAG AGGACAACTTCTCAATGATCATGATAGTTATTTAGTAAGAAATAATGGTTGTTAATCAAATACATGTTATGTCTTGTCCTTCTCTGATTT TTCTGACTTGGATTCCTTAATTTGCAGTGATGTCTTAGAAATGGAAAAAGTATCCTCTGGGCTTTCAGACTTTCAGCAACAACAGCCAGT GGGATACCTCTGAGTTCTTGTGTTCTAGTCTCTTGTATGTCCTGAAAGGCAGCAGGAGCATTTTTGGGGTCACACTGATATTTTGTTAAA GCAGAGTTTCCTGCATGGTTTATGGTGCTGCTCTAATATTTTCTCTTTAAAACTGTGTCAATTTTTGGAGAATGAATTTTTCAACCTTTT CATTGTGGAGGATTTTTCCCACAAGGTAGTAATGGGCAATGGATCAAAATCCTATCATAAATGATTGAATTTTCAATGTCATAGTGTGTG GAAATACTACTCCCTTTCCTCCATGTCTATCTTCTTAGATGTTCTGTCTTTGTCATCATCTGCTCCAGCACATACTTTGGACTCCTTTAC AGGTGACCTTCCCCCCTCCCTCCTCAATAGGTGTCCTCAGTGTTTTCTAAGCATTTAAAACTGAATTTGACAAGTGGCTAAAAACTTAGT CTGAGACTTGTACTTAGTATATGGTTAATTATAGAAACAACAACTATTTTAAACAGTTACTCTGTTGACTGCTCTTTATGACTACACTTG TATGCCAGGAGGCAGCAGCCTATACACCATTAGACTCTTTACAAGCAACCAACGAACCAATTGCAGTGGTTGCAGTTGTCACAGTAGTCT TGCCTGGGCCAGACTGGGCTGGGCTGTGGGAAGCATTCCCCTTCAGGGGAGTTTCCACAGCTCAGCCCAGGCTCCAGTCTGGCTAGAGAG CATCCAGCCCATTCCTTGCCTCAGTGCCACCTTTTTCTGGGCAAGTAGCCAAGAAGTGACTTTATATGCAGTGAGTACTTCAGATAAACT TACAGCTACAGCTGCCGAAGAGTGGAGAAGGTTGACCACCATTTATTTAATTCTCTAGTGTAAAAACAATTGAGAGCAGTGTGCGTGAGC CCACAGACACCTGTGTTTCTGGGAGCTCTGGCAGTGGCGGATTCATAGGCACTTGGGCTGCACTTTGAATGACACACTTGGCTTTATTAG ATTCACTAGTTTTTAAAAAATTGTTGTTCGTTTCTTTTCATTAAAGGTTTAATCAGACAGATCAGACAGCATAATTTTGTATTTAATGAC AGAAACGTTGGTACATTTCTTCATGAATGAGCTTGCATTCTGAAGCAAGAGCCTACAAAAGGCACTTGTTATAAATGAAAGTTCTGGCTC TAGAGGCCAGTACTCTGGAGTTTCAGAGCAGCCAGTGATTGTTCCAGTCAGTGATGCCTAGTTATATAGAGGAGGAGTACACTGTGCACT CTTCTAGGTGTAAGGGTATGCAACTTTGGATCTTAAAATTCTGTACACATACACACTTTATATATATGTATGTATGTATGAAAACATGAA ATTAGTTTGTCAAATATGTGTGTGTTTAGTATTTTAGCTTAGTGCAACTATTTCCACATTATTTATTAAATTGATCTAAGACACTTTCTT GTTGACACCTTGAATATTAATGTTCAAGGGTGCAATGTGTATTCCTTTAGATTGTTAAAGCTTAATTACTATGATTTGTAGTAAATTAAC TTTTAAAATGTATTTGAGCCCTTCTGTAGTGTCGTAGGGCTCTTACAGGGTGGGAAAGATTTTAATTTTCCAGTTGCTAATTGAACAGTA TGGCCTCATTATATATTTTGATTTATAGGAGTTTGTGTCTGGGTCCCAGGAACATCTACTGGGGATGACTGTTAGGCAGCTTGTGATGAT GTTTTTTAAAAAACCTAAGTAACTTGGGGAGACAGAGCATTTCAAACCCATATAGACACCTATCATACCTGTATATCCCCTAATACATGG AACATAAATTTCATTTCAGCTTTATGCATTAATGTATTGAAGAGGCAGGCTTTTTTTCCAGTAATAATACTGTACATCTAAGGTTGCTAT TCAGTAAAACTAATAGAAGAGATAATTATTGAATACCTTGGAATATGTAGTGAGAAGAGGCCAAATTTTTCATGTTTGTGAGCATGTCTT TCAGATACTCGCTAATGGAGAAATTCACTTTAGACCTCTAGACCCCAAAACCAAGTTAGCAAGTGACAAAAAGTAAATTATTAATAGTCT GTAAAGTGGATGCTGGTCTTACAAAGCTCCTATTCACATGAACCCTATGGTTAATTAGAAAGAACTTGCTGTCTCCAGAAAAGGGAATGG AAATAATAACTATGTATCTTCTTTTCATGTAATTTGGTCACAGAATAAGGTATTCAAGTTAAGTCTAATCCAAGTCTTAGAGATCTTTAA GTATCCTAAAATAGCAGCCTAAGTAGTCATCATGTAAAGAAGTTGACTTTCAGGAATGTCAGCATTGACCTCTCCTTGCCACTGTTACTC AGCTAAACATAACTTGCCATTCTTAAAAATAAAAAAGCTCCCACCCAGAAACTCTAGTGATACTCAGTTTTGACCTCTTACTGCTTCCAT GTGGGACTTCTTTTCAGCTTTTAACCATTGGAATTTTCTACCTGCTATGTTCCTCTCTGGAAAATATCAATTTGGAAATGCTGCCTTTCA AATCAATGCCATGATCATCCATATTGTTGAGTTTGTTGTTGGTGTTCCAGAAGTGTCCCCATTTTACAACTTTATGCACACACCTGGCAA ATCATTAACATGAGCATTCAACAGTACTGGGATGGGTGGGGTGGGGGTAGGGGGCTCACCAACAGAACTGGCCAGTTGACATTGCCTGAA AAGGCACCACCTTTAAGGGCCAGTTGTGGGGTTGGTAAGCACAGTTATGAAAATTTCTATCTAGCCTCCGTTTTGAATGGTTTTAAGAAA TTTTGTATATGGAGGATGGAAATGCTTATATATTTATTGAAAATCCTTTTATTTGAAATTAAAATTATTTGGTATATAATTGTTTGATAT TTGGGGAGGGTTTTGGAGGGGAGATAATGTCACTGATAAATTAAAAGCCTGTTGATTTTGCAGAAAGGTACTGTTAGTGACTGATAAGGA TGCCTTTGTTTTGTACATGAACCAAATCTTTGTTTTACATTTCTTTTATCCAAAATATTTAGGCATCTGACATTTTCAACCAGAATTTCA ATTATATACTGTGATTTTTATTTGTTGCAATACATTACAATTTCAGAGGTACTTTGGGGCTCAAAAGCTAGGATTTCTAAGTCAGTATGT GCATTTCACACGATAAAGCTGTTAATGGTGAGCAAAGTATTATATACTAACTAGATTTTTCCACATCTGTATAGTATATTATATGTATTT TGTGGTATTGAGAGTATAGAAAGTTTAGAGTGTCAAACATGCGTTTAATGTGTATTTTTAAACAAATTTATGGCAATTAAAATATTTGGA GACAAGGGTATCACATTTCAATTTGTAAAGATCTTTTTAACTCTACTGTGTCATTAAGATGCTTTGTACAATGCCAAACCATAGTTGGAG >43140_43140_5_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000389506_AFF4_chr5_132240096_ENST00000265343_length(amino acids)=2175AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDS SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDT SGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS RKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEE KELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKN SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV KEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFP MYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVS PKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLVRYT -------------------------------------------------------------- >43140_43140_6_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000389506_AFF4_chr5_132240096_ENST00000378595_length(transcript)=6020nt_BP=4086nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCT AAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGT GATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCT AGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAG AGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCC GCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACA AGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAA TCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCT CGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCA AGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAG AAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTAC CCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAG AAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGA AAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAA AAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAAT TCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCT GTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAAC AAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTT AAGGTAAAGTGTTGGGGGCCTGGGGCTTTTGAAAATCATTCAACTTGCCATGTGACTTTTCCAGGGTGACACTGTGCTTTGAAATTATTG TAACATCTCAGTAAATATATAGGCCTATGTCTTTTACCCTCTATATGTAATAATCCTGATAAATGAATACAGTGATATAAGACTGTGAAG GTGGTAAGTCAGCTGGTCACATACATATTGAAAGAAAAACCCTTGGGTACAGTGGCTCATACCTGTAGTCCCAGCTATTTGGGAGGCTAA >43140_43140_6_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000389506_AFF4_chr5_132240096_ENST00000378595_length(amino acids)=1912AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDS SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDT SGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS RKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEE KELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKN SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV -------------------------------------------------------------- >43140_43140_7_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000389506_AFF4_chr5_132262899_ENST00000265343_length(transcript)=12295nt_BP=4086nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACGCATTCATGGCCTCCCCCTCTAACGGCTATTCATACACCATGCAAA ACAGAACCTTCCAAATTTCCTTTTCCAACTAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAA ACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGAT AAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGT AGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGT GCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCC TCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGT GGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCT CCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGT GGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGG AAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAA TCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCC GAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAG GAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAG CCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAA GTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCA GCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTT CCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAG GAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAG GAAAAGGCTCCAAGTAGCTCCTCTAACTGTCCTCCATCTGCACCAACTCTTGATTCTTCTAAGCCTCGGAGAACAAAGCTTGTCTTTGAT GACAGAAATTATTCAGCAGACCATTATTTACAAGAAGCAAAAAAGCTAAAGCACAATGCAGATGCATTGTCTGATAGGTTTGAGAAAGCT GTATACTATCTTGATGCTGTGGTATCTTTCATTGAATGTGGGAATGCATTAGAGAAGAATGCTCAGGAATCCAAATCCCCATTCCCTATG TATTCAGAGACGGTGGATCTCATCAAATACACTATGAAGCTAAAGAATTACTTGGCACCAGATGCTACAGCTGCAGATAAACGACTCACA GTACTTTGCCTGCGATGCGAGTCTTTGCTGTACCTGAGGCTGTTCAAACTGAAGAAGGAAAATGCTCTGAAGTACTCAAAGACACTGACA GAGCACCTGAAGAATTCTTATAATAATTCTCAAGCACCATCGCCTGGCTTGGGAAGCAAAGCTGTGGGGATGCCTTCCCCTGTTTCTCCA AAGCTGTCACCAGGCAATTCAGGAAATTATTCATCTGGGGCCAGTAGTGCTTCTGCAAGTGGTTCTTCAGTGACCATTCCACAGAAGATC CACCAGATGGCAGCCAGCTATGTTCAGGTCACATCCAACTTCCTCTATGCCACCGAAATTTGGGACCAAGCTGAACAGCTTTCCAAAGAG CAAAAAGAATTCTTTGCTGAACTGGATAAAGTAATGGGCCCTCTCATCTTTAATGCAAGCATCATGACAGATCTAGTTCGTTATACCCGG CAGGGACTGCACTGGCTTCGCCAGGATGCCAAGTTGATATCTTGAACTGAACACATTCTCGTTGCCTCTGATTTTCTCCACAACACTGTG TCACATCACGAAGGAAAACTGCCATAACATACCACCTAGTCGACACTAAGAATGAGGAATAGTTTTCTCCTCGTTGGTTCATGTGTTGTT GTTTTTGATAATCCAAAGCGATCATGTCAGTTGGCCCTTTAATATTTCCAATGTGAAAGATTATTTAAATGCTTTTAAATCTGCAGCACA TTGATAAGATGGTTTCCGTGAGCTATGATAAGATTGAAATTCCAGTTGCAATTCATAACTAATGAATTGAAATTTTATTTATTTTAATTT TTTTAAGTTCCCAGATTGGGGCTAGTTTAAGACTTAGTTATTTCTGCCTATAAATTTACTCTGTTGAATATTTAGCATAAATTTAATGTA GACATTTTTATTTATATACCTTGGGAGCTTTATTACCTAATATCTTTTTGTGGTAGCTGTTCTAAGAGTAAGAATTGGTTCGTCTAAAAT AAGGACATATTCTTTCTACACCTGCTACCTGACCTGATATTTGAAATCTTAACTCCAATTTTATTATTGTGGAATTTACAGTTAGTATTA AGGATATTCTTCTACACATGAAAAAATCACTTAAATATGAGAAAATGGCATTCTACATGTATGTACTATGAAATGTGTCTGATTTGGTAT GCATTATTTCAAAAACTGTGAATGTGTGTTAATAACACTACAGCAATCACACAGTGACTATAGCTTGCATTTAATGCATTACAAAAGAGG GAGGACAAACTTTCTAGAAGAAGCATTTCATGTTGAAGGGTTTCATAAAAGGACAATCCTGAACGTTACGGATTTTATTAAAACCATATG TTATTTTTTGTTGCTAATCATTTGACACTTAATCGAAACAGAATAAGTTACTGTGGAAAAAAGGATGATCCAACTCCTGAGGATTGCCGC CTGTGTGTCTTTAATTGATTATCTTTGATAGTTAGAGTTATTTTTCAGATTTTTCCCCCTCATACTGGATTGTGATGCTCTGATATGAGC ATGCAATGACTGATACAGAAATAGGCTGGAGCTTCGGTGTGTGCTTTTGCTATACAGCTTACAGTTCTAATGCCTGATGTAGAGATGATG AATTTCTCCTTTTTAAACCTATCTTCTGTTTACTCCTTTTGCATTATGAAGGCCCTCTTCAATGATGTATGTTTCTGATGGAATCAGAAA ATTTCACACTAGAAAAGTGTACCTAACTTGATTCAGTGTGAGCTCTTGGGACAGGGAGTGGAGCCAGGGGTAGAGCTTAAAGAAGCTGGC TCTGTAAGAGTTGTATATCAAAGTACCTTTTGCTACAAGGTGCATATAGAAGTCTAAGATAAGAAATGTACCCTCTATACTTTATTTTTC ATGCCCCTATCATGTTTGGTGTGCCTTAAATCTTACCTTTAAATGAAGACTCTATGGATTGTTTACAAATGAAGTTTTACACTAGGACCA GATCGTCCATACATGATTGGTCTTCTACAATAATAATGTTCAATTCTTTCATTTTAAATCTTTCTTTAGGGTCATATAAAGATTAGTTCT TTCAGAAAAGCTATTGCTTTGGTACATGACTTAGTCTAACCAGTTGGGTAATGCTGCTTTGAAAAATAGTTTGTCCCTCTCCCCATTCCA AAAATGAATCCATTCAGTCAGAAAAAAAGATTATCCTACTATTTGTAGATGATTGCTAAGGCTTGAAATAGGAAAGGGGAAAGAAGGGAT AGAAAAGTTTCAAGTCCAGTAGTGCAGTGAATCCTTTGTGTTTGAGACTTTTTTACACTTATTTCTGAAGTTAGTGAACTTTCATTGTCC CTGTGGCCTCATATTTATAGAGCTTCTTAACTGTTTTGTACCTCAGATTGTTTTTAGATGTCATTGAAGATTGAGATGTACAAATTATGT TGAATTTAACCTGTTTCTCTTGGAGAAATTGCCTCTGATATCTTTCTAACTTAATCTTAGTGTGTTCTAGGAACAGTTTTCCATAAGAGG ACAACTTCTCAATGATCATGATAGTTATTTAGTAAGAAATAATGGTTGTTAATCAAATACATGTTATGTCTTGTCCTTCTCTGATTTTTC TGACTTGGATTCCTTAATTTGCAGTGATGTCTTAGAAATGGAAAAAGTATCCTCTGGGCTTTCAGACTTTCAGCAACAACAGCCAGTGGG ATACCTCTGAGTTCTTGTGTTCTAGTCTCTTGTATGTCCTGAAAGGCAGCAGGAGCATTTTTGGGGTCACACTGATATTTTGTTAAAGCA GAGTTTCCTGCATGGTTTATGGTGCTGCTCTAATATTTTCTCTTTAAAACTGTGTCAATTTTTGGAGAATGAATTTTTCAACCTTTTCAT TGTGGAGGATTTTTCCCACAAGGTAGTAATGGGCAATGGATCAAAATCCTATCATAAATGATTGAATTTTCAATGTCATAGTGTGTGGAA ATACTACTCCCTTTCCTCCATGTCTATCTTCTTAGATGTTCTGTCTTTGTCATCATCTGCTCCAGCACATACTTTGGACTCCTTTACAGG TGACCTTCCCCCCTCCCTCCTCAATAGGTGTCCTCAGTGTTTTCTAAGCATTTAAAACTGAATTTGACAAGTGGCTAAAAACTTAGTCTG AGACTTGTACTTAGTATATGGTTAATTATAGAAACAACAACTATTTTAAACAGTTACTCTGTTGACTGCTCTTTATGACTACACTTGTAT GCCAGGAGGCAGCAGCCTATACACCATTAGACTCTTTACAAGCAACCAACGAACCAATTGCAGTGGTTGCAGTTGTCACAGTAGTCTTGC CTGGGCCAGACTGGGCTGGGCTGTGGGAAGCATTCCCCTTCAGGGGAGTTTCCACAGCTCAGCCCAGGCTCCAGTCTGGCTAGAGAGCAT CCAGCCCATTCCTTGCCTCAGTGCCACCTTTTTCTGGGCAAGTAGCCAAGAAGTGACTTTATATGCAGTGAGTACTTCAGATAAACTTAC AGCTACAGCTGCCGAAGAGTGGAGAAGGTTGACCACCATTTATTTAATTCTCTAGTGTAAAAACAATTGAGAGCAGTGTGCGTGAGCCCA CAGACACCTGTGTTTCTGGGAGCTCTGGCAGTGGCGGATTCATAGGCACTTGGGCTGCACTTTGAATGACACACTTGGCTTTATTAGATT CACTAGTTTTTAAAAAATTGTTGTTCGTTTCTTTTCATTAAAGGTTTAATCAGACAGATCAGACAGCATAATTTTGTATTTAATGACAGA AACGTTGGTACATTTCTTCATGAATGAGCTTGCATTCTGAAGCAAGAGCCTACAAAAGGCACTTGTTATAAATGAAAGTTCTGGCTCTAG AGGCCAGTACTCTGGAGTTTCAGAGCAGCCAGTGATTGTTCCAGTCAGTGATGCCTAGTTATATAGAGGAGGAGTACACTGTGCACTCTT CTAGGTGTAAGGGTATGCAACTTTGGATCTTAAAATTCTGTACACATACACACTTTATATATATGTATGTATGTATGAAAACATGAAATT AGTTTGTCAAATATGTGTGTGTTTAGTATTTTAGCTTAGTGCAACTATTTCCACATTATTTATTAAATTGATCTAAGACACTTTCTTGTT GACACCTTGAATATTAATGTTCAAGGGTGCAATGTGTATTCCTTTAGATTGTTAAAGCTTAATTACTATGATTTGTAGTAAATTAACTTT TAAAATGTATTTGAGCCCTTCTGTAGTGTCGTAGGGCTCTTACAGGGTGGGAAAGATTTTAATTTTCCAGTTGCTAATTGAACAGTATGG CCTCATTATATATTTTGATTTATAGGAGTTTGTGTCTGGGTCCCAGGAACATCTACTGGGGATGACTGTTAGGCAGCTTGTGATGATGTT TTTTAAAAAACCTAAGTAACTTGGGGAGACAGAGCATTTCAAACCCATATAGACACCTATCATACCTGTATATCCCCTAATACATGGAAC ATAAATTTCATTTCAGCTTTATGCATTAATGTATTGAAGAGGCAGGCTTTTTTTCCAGTAATAATACTGTACATCTAAGGTTGCTATTCA GTAAAACTAATAGAAGAGATAATTATTGAATACCTTGGAATATGTAGTGAGAAGAGGCCAAATTTTTCATGTTTGTGAGCATGTCTTTCA GATACTCGCTAATGGAGAAATTCACTTTAGACCTCTAGACCCCAAAACCAAGTTAGCAAGTGACAAAAAGTAAATTATTAATAGTCTGTA AAGTGGATGCTGGTCTTACAAAGCTCCTATTCACATGAACCCTATGGTTAATTAGAAAGAACTTGCTGTCTCCAGAAAAGGGAATGGAAA TAATAACTATGTATCTTCTTTTCATGTAATTTGGTCACAGAATAAGGTATTCAAGTTAAGTCTAATCCAAGTCTTAGAGATCTTTAAGTA TCCTAAAATAGCAGCCTAAGTAGTCATCATGTAAAGAAGTTGACTTTCAGGAATGTCAGCATTGACCTCTCCTTGCCACTGTTACTCAGC TAAACATAACTTGCCATTCTTAAAAATAAAAAAGCTCCCACCCAGAAACTCTAGTGATACTCAGTTTTGACCTCTTACTGCTTCCATGTG GGACTTCTTTTCAGCTTTTAACCATTGGAATTTTCTACCTGCTATGTTCCTCTCTGGAAAATATCAATTTGGAAATGCTGCCTTTCAAAT CAATGCCATGATCATCCATATTGTTGAGTTTGTTGTTGGTGTTCCAGAAGTGTCCCCATTTTACAACTTTATGCACACACCTGGCAAATC ATTAACATGAGCATTCAACAGTACTGGGATGGGTGGGGTGGGGGTAGGGGGCTCACCAACAGAACTGGCCAGTTGACATTGCCTGAAAAG GCACCACCTTTAAGGGCCAGTTGTGGGGTTGGTAAGCACAGTTATGAAAATTTCTATCTAGCCTCCGTTTTGAATGGTTTTAAGAAATTT TGTATATGGAGGATGGAAATGCTTATATATTTATTGAAAATCCTTTTATTTGAAATTAAAATTATTTGGTATATAATTGTTTGATATTTG GGGAGGGTTTTGGAGGGGAGATAATGTCACTGATAAATTAAAAGCCTGTTGATTTTGCAGAAAGGTACTGTTAGTGACTGATAAGGATGC CTTTGTTTTGTACATGAACCAAATCTTTGTTTTACATTTCTTTTATCCAAAATATTTAGGCATCTGACATTTTCAACCAGAATTTCAATT ATATACTGTGATTTTTATTTGTTGCAATACATTACAATTTCAGAGGTACTTTGGGGCTCAAAAGCTAGGATTTCTAAGTCAGTATGTGCA TTTCACACGATAAAGCTGTTAATGGTGAGCAAAGTATTATATACTAACTAGATTTTTCCACATCTGTATAGTATATTATATGTATTTTGT GGTATTGAGAGTATAGAAAGTTTAGAGTGTCAAACATGCGTTTAATGTGTATTTTTAAACAAATTTATGGCAATTAAAATATTTGGAGAC AAGGGTATCACATTTCAATTTGTAAAGATCTTTTTAACTCTACTGTGTCATTAAGATGCTTTGTACAATGCCAAACCATAGTTGGAGAAA >43140_43140_7_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000389506_AFF4_chr5_132262899_ENST00000265343_length(amino acids)=2204AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCD KTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPA SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPR GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYP ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEK VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNK ETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKA VYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLT EHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKE -------------------------------------------------------------- >43140_43140_8_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000389506_AFF4_chr5_132262899_ENST00000378595_length(transcript)=6107nt_BP=4086nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACGCATTCATGGCCTCCCCCTCTAACGGCTATTCATACACCATGCAAA ACAGAACCTTCCAAATTTCCTTTTCCAACTAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAA ACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGAT AAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGT AGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGT GCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCC TCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGT GGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCT CCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGT GGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGG AAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAA TCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCC GAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAG GAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAG CCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAA GTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCA GCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTT CCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAG GAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAG GTAAAGTGTTGGGGGCCTGGGGCTTTTGAAAATCATTCAACTTGCCATGTGACTTTTCCAGGGTGACACTGTGCTTTGAAATTATTGTAA CATCTCAGTAAATATATAGGCCTATGTCTTTTACCCTCTATATGTAATAATCCTGATAAATGAATACAGTGATATAAGACTGTGAAGGTG GTAAGTCAGCTGGTCACATACATATTGAAAGAAAAACCCTTGGGTACAGTGGCTCATACCTGTAGTCCCAGCTATTTGGGAGGCTAAGAT >43140_43140_8_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000389506_AFF4_chr5_132262899_ENST00000378595_length(amino acids)=1941AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCD KTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPA SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPR GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYP ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEK VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNK -------------------------------------------------------------- >43140_43140_9_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000534358_AFF4_chr5_132240096_ENST00000265343_length(transcript)=12231nt_BP=4109nt CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAG AACAAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAG ACAGTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAG CAGATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACA GTGAGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAG TGAACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCA CTGGGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAG AAAGTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTG AGAAGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGAC ACAAAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATA AGTCAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTC CTTCCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAAC GAATGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGA ATCTTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAG AGGCTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGA AACCCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATT TGTTGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCT TAAAGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGA CTTCCAGTAGCTCCAAGGAGGTTAAGGAAAAGGCTCCAAGTAGCTCCTCTAACTGTCCTCCATCTGCACCAACTCTTGATTCTTCTAAGC CTCGGAGAACAAAGCTTGTCTTTGATGACAGAAATTATTCAGCAGACCATTATTTACAAGAAGCAAAAAAGCTAAAGCACAATGCAGATG CATTGTCTGATAGGTTTGAGAAAGCTGTATACTATCTTGATGCTGTGGTATCTTTCATTGAATGTGGGAATGCATTAGAGAAGAATGCTC AGGAATCCAAATCCCCATTCCCTATGTATTCAGAGACGGTGGATCTCATCAAATACACTATGAAGCTAAAGAATTACTTGGCACCAGATG CTACAGCTGCAGATAAACGACTCACAGTACTTTGCCTGCGATGCGAGTCTTTGCTGTACCTGAGGCTGTTCAAACTGAAGAAGGAAAATG CTCTGAAGTACTCAAAGACACTGACAGAGCACCTGAAGAATTCTTATAATAATTCTCAAGCACCATCGCCTGGCTTGGGAAGCAAAGCTG TGGGGATGCCTTCCCCTGTTTCTCCAAAGCTGTCACCAGGCAATTCAGGAAATTATTCATCTGGGGCCAGTAGTGCTTCTGCAAGTGGTT CTTCAGTGACCATTCCACAGAAGATCCACCAGATGGCAGCCAGCTATGTTCAGGTCACATCCAACTTCCTCTATGCCACCGAAATTTGGG ACCAAGCTGAACAGCTTTCCAAAGAGCAAAAAGAATTCTTTGCTGAACTGGATAAAGTAATGGGCCCTCTCATCTTTAATGCAAGCATCA TGACAGATCTAGTTCGTTATACCCGGCAGGGACTGCACTGGCTTCGCCAGGATGCCAAGTTGATATCTTGAACTGAACACATTCTCGTTG CCTCTGATTTTCTCCACAACACTGTGTCACATCACGAAGGAAAACTGCCATAACATACCACCTAGTCGACACTAAGAATGAGGAATAGTT TTCTCCTCGTTGGTTCATGTGTTGTTGTTTTTGATAATCCAAAGCGATCATGTCAGTTGGCCCTTTAATATTTCCAATGTGAAAGATTAT TTAAATGCTTTTAAATCTGCAGCACATTGATAAGATGGTTTCCGTGAGCTATGATAAGATTGAAATTCCAGTTGCAATTCATAACTAATG AATTGAAATTTTATTTATTTTAATTTTTTTAAGTTCCCAGATTGGGGCTAGTTTAAGACTTAGTTATTTCTGCCTATAAATTTACTCTGT TGAATATTTAGCATAAATTTAATGTAGACATTTTTATTTATATACCTTGGGAGCTTTATTACCTAATATCTTTTTGTGGTAGCTGTTCTA AGAGTAAGAATTGGTTCGTCTAAAATAAGGACATATTCTTTCTACACCTGCTACCTGACCTGATATTTGAAATCTTAACTCCAATTTTAT TATTGTGGAATTTACAGTTAGTATTAAGGATATTCTTCTACACATGAAAAAATCACTTAAATATGAGAAAATGGCATTCTACATGTATGT ACTATGAAATGTGTCTGATTTGGTATGCATTATTTCAAAAACTGTGAATGTGTGTTAATAACACTACAGCAATCACACAGTGACTATAGC TTGCATTTAATGCATTACAAAAGAGGGAGGACAAACTTTCTAGAAGAAGCATTTCATGTTGAAGGGTTTCATAAAAGGACAATCCTGAAC GTTACGGATTTTATTAAAACCATATGTTATTTTTTGTTGCTAATCATTTGACACTTAATCGAAACAGAATAAGTTACTGTGGAAAAAAGG ATGATCCAACTCCTGAGGATTGCCGCCTGTGTGTCTTTAATTGATTATCTTTGATAGTTAGAGTTATTTTTCAGATTTTTCCCCCTCATA CTGGATTGTGATGCTCTGATATGAGCATGCAATGACTGATACAGAAATAGGCTGGAGCTTCGGTGTGTGCTTTTGCTATACAGCTTACAG TTCTAATGCCTGATGTAGAGATGATGAATTTCTCCTTTTTAAACCTATCTTCTGTTTACTCCTTTTGCATTATGAAGGCCCTCTTCAATG ATGTATGTTTCTGATGGAATCAGAAAATTTCACACTAGAAAAGTGTACCTAACTTGATTCAGTGTGAGCTCTTGGGACAGGGAGTGGAGC CAGGGGTAGAGCTTAAAGAAGCTGGCTCTGTAAGAGTTGTATATCAAAGTACCTTTTGCTACAAGGTGCATATAGAAGTCTAAGATAAGA AATGTACCCTCTATACTTTATTTTTCATGCCCCTATCATGTTTGGTGTGCCTTAAATCTTACCTTTAAATGAAGACTCTATGGATTGTTT ACAAATGAAGTTTTACACTAGGACCAGATCGTCCATACATGATTGGTCTTCTACAATAATAATGTTCAATTCTTTCATTTTAAATCTTTC TTTAGGGTCATATAAAGATTAGTTCTTTCAGAAAAGCTATTGCTTTGGTACATGACTTAGTCTAACCAGTTGGGTAATGCTGCTTTGAAA AATAGTTTGTCCCTCTCCCCATTCCAAAAATGAATCCATTCAGTCAGAAAAAAAGATTATCCTACTATTTGTAGATGATTGCTAAGGCTT GAAATAGGAAAGGGGAAAGAAGGGATAGAAAAGTTTCAAGTCCAGTAGTGCAGTGAATCCTTTGTGTTTGAGACTTTTTTACACTTATTT CTGAAGTTAGTGAACTTTCATTGTCCCTGTGGCCTCATATTTATAGAGCTTCTTAACTGTTTTGTACCTCAGATTGTTTTTAGATGTCAT TGAAGATTGAGATGTACAAATTATGTTGAATTTAACCTGTTTCTCTTGGAGAAATTGCCTCTGATATCTTTCTAACTTAATCTTAGTGTG TTCTAGGAACAGTTTTCCATAAGAGGACAACTTCTCAATGATCATGATAGTTATTTAGTAAGAAATAATGGTTGTTAATCAAATACATGT TATGTCTTGTCCTTCTCTGATTTTTCTGACTTGGATTCCTTAATTTGCAGTGATGTCTTAGAAATGGAAAAAGTATCCTCTGGGCTTTCA GACTTTCAGCAACAACAGCCAGTGGGATACCTCTGAGTTCTTGTGTTCTAGTCTCTTGTATGTCCTGAAAGGCAGCAGGAGCATTTTTGG GGTCACACTGATATTTTGTTAAAGCAGAGTTTCCTGCATGGTTTATGGTGCTGCTCTAATATTTTCTCTTTAAAACTGTGTCAATTTTTG GAGAATGAATTTTTCAACCTTTTCATTGTGGAGGATTTTTCCCACAAGGTAGTAATGGGCAATGGATCAAAATCCTATCATAAATGATTG AATTTTCAATGTCATAGTGTGTGGAAATACTACTCCCTTTCCTCCATGTCTATCTTCTTAGATGTTCTGTCTTTGTCATCATCTGCTCCA GCACATACTTTGGACTCCTTTACAGGTGACCTTCCCCCCTCCCTCCTCAATAGGTGTCCTCAGTGTTTTCTAAGCATTTAAAACTGAATT TGACAAGTGGCTAAAAACTTAGTCTGAGACTTGTACTTAGTATATGGTTAATTATAGAAACAACAACTATTTTAAACAGTTACTCTGTTG ACTGCTCTTTATGACTACACTTGTATGCCAGGAGGCAGCAGCCTATACACCATTAGACTCTTTACAAGCAACCAACGAACCAATTGCAGT GGTTGCAGTTGTCACAGTAGTCTTGCCTGGGCCAGACTGGGCTGGGCTGTGGGAAGCATTCCCCTTCAGGGGAGTTTCCACAGCTCAGCC CAGGCTCCAGTCTGGCTAGAGAGCATCCAGCCCATTCCTTGCCTCAGTGCCACCTTTTTCTGGGCAAGTAGCCAAGAAGTGACTTTATAT GCAGTGAGTACTTCAGATAAACTTACAGCTACAGCTGCCGAAGAGTGGAGAAGGTTGACCACCATTTATTTAATTCTCTAGTGTAAAAAC AATTGAGAGCAGTGTGCGTGAGCCCACAGACACCTGTGTTTCTGGGAGCTCTGGCAGTGGCGGATTCATAGGCACTTGGGCTGCACTTTG AATGACACACTTGGCTTTATTAGATTCACTAGTTTTTAAAAAATTGTTGTTCGTTTCTTTTCATTAAAGGTTTAATCAGACAGATCAGAC AGCATAATTTTGTATTTAATGACAGAAACGTTGGTACATTTCTTCATGAATGAGCTTGCATTCTGAAGCAAGAGCCTACAAAAGGCACTT GTTATAAATGAAAGTTCTGGCTCTAGAGGCCAGTACTCTGGAGTTTCAGAGCAGCCAGTGATTGTTCCAGTCAGTGATGCCTAGTTATAT AGAGGAGGAGTACACTGTGCACTCTTCTAGGTGTAAGGGTATGCAACTTTGGATCTTAAAATTCTGTACACATACACACTTTATATATAT GTATGTATGTATGAAAACATGAAATTAGTTTGTCAAATATGTGTGTGTTTAGTATTTTAGCTTAGTGCAACTATTTCCACATTATTTATT AAATTGATCTAAGACACTTTCTTGTTGACACCTTGAATATTAATGTTCAAGGGTGCAATGTGTATTCCTTTAGATTGTTAAAGCTTAATT ACTATGATTTGTAGTAAATTAACTTTTAAAATGTATTTGAGCCCTTCTGTAGTGTCGTAGGGCTCTTACAGGGTGGGAAAGATTTTAATT TTCCAGTTGCTAATTGAACAGTATGGCCTCATTATATATTTTGATTTATAGGAGTTTGTGTCTGGGTCCCAGGAACATCTACTGGGGATG ACTGTTAGGCAGCTTGTGATGATGTTTTTTAAAAAACCTAAGTAACTTGGGGAGACAGAGCATTTCAAACCCATATAGACACCTATCATA CCTGTATATCCCCTAATACATGGAACATAAATTTCATTTCAGCTTTATGCATTAATGTATTGAAGAGGCAGGCTTTTTTTCCAGTAATAA TACTGTACATCTAAGGTTGCTATTCAGTAAAACTAATAGAAGAGATAATTATTGAATACCTTGGAATATGTAGTGAGAAGAGGCCAAATT TTTCATGTTTGTGAGCATGTCTTTCAGATACTCGCTAATGGAGAAATTCACTTTAGACCTCTAGACCCCAAAACCAAGTTAGCAAGTGAC AAAAAGTAAATTATTAATAGTCTGTAAAGTGGATGCTGGTCTTACAAAGCTCCTATTCACATGAACCCTATGGTTAATTAGAAAGAACTT GCTGTCTCCAGAAAAGGGAATGGAAATAATAACTATGTATCTTCTTTTCATGTAATTTGGTCACAGAATAAGGTATTCAAGTTAAGTCTA ATCCAAGTCTTAGAGATCTTTAAGTATCCTAAAATAGCAGCCTAAGTAGTCATCATGTAAAGAAGTTGACTTTCAGGAATGTCAGCATTG ACCTCTCCTTGCCACTGTTACTCAGCTAAACATAACTTGCCATTCTTAAAAATAAAAAAGCTCCCACCCAGAAACTCTAGTGATACTCAG TTTTGACCTCTTACTGCTTCCATGTGGGACTTCTTTTCAGCTTTTAACCATTGGAATTTTCTACCTGCTATGTTCCTCTCTGGAAAATAT CAATTTGGAAATGCTGCCTTTCAAATCAATGCCATGATCATCCATATTGTTGAGTTTGTTGTTGGTGTTCCAGAAGTGTCCCCATTTTAC AACTTTATGCACACACCTGGCAAATCATTAACATGAGCATTCAACAGTACTGGGATGGGTGGGGTGGGGGTAGGGGGCTCACCAACAGAA CTGGCCAGTTGACATTGCCTGAAAAGGCACCACCTTTAAGGGCCAGTTGTGGGGTTGGTAAGCACAGTTATGAAAATTTCTATCTAGCCT CCGTTTTGAATGGTTTTAAGAAATTTTGTATATGGAGGATGGAAATGCTTATATATTTATTGAAAATCCTTTTATTTGAAATTAAAATTA TTTGGTATATAATTGTTTGATATTTGGGGAGGGTTTTGGAGGGGAGATAATGTCACTGATAAATTAAAAGCCTGTTGATTTTGCAGAAAG GTACTGTTAGTGACTGATAAGGATGCCTTTGTTTTGTACATGAACCAAATCTTTGTTTTACATTTCTTTTATCCAAAATATTTAGGCATC TGACATTTTCAACCAGAATTTCAATTATATACTGTGATTTTTATTTGTTGCAATACATTACAATTTCAGAGGTACTTTGGGGCTCAAAAG CTAGGATTTCTAAGTCAGTATGTGCATTTCACACGATAAAGCTGTTAATGGTGAGCAAAGTATTATATACTAACTAGATTTTTCCACATC TGTATAGTATATTATATGTATTTTGTGGTATTGAGAGTATAGAAAGTTTAGAGTGTCAAACATGCGTTTAATGTGTATTTTTAAACAAAT TTATGGCAATTAAAATATTTGGAGACAAGGGTATCACATTTCAATTTGTAAAGATCTTTTTAACTCTACTGTGTCATTAAGATGCTTTGT >43140_43140_9_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000534358_AFF4_chr5_132240096_ENST00000265343_length(amino acids)=2175AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDS SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDT SGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS RKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEE KELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKN SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV KEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFP MYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVS PKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKEQKEFFAELDKVMGPLIFNASIMTDLVRYT -------------------------------------------------------------- >43140_43140_10_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000534358_AFF4_chr5_132240096_ENST00000378595_length(transcript)=6043nt_BP=4109nt CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAG AACAAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAG ACAGTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAG CAGATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACA GTGAGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAG TGAACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCA CTGGGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAG AAAGTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTG AGAAGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGAC ACAAAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATA AGTCAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTC CTTCCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAAC GAATGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGA ATCTTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAG AGGCTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGA AACCCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATT TGTTGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCT TAAAGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGA CTTCCAGTAGCTCCAAGGAGGTTAAGGTAAAGTGTTGGGGGCCTGGGGCTTTTGAAAATCATTCAACTTGCCATGTGACTTTTCCAGGGT GACACTGTGCTTTGAAATTATTGTAACATCTCAGTAAATATATAGGCCTATGTCTTTTACCCTCTATATGTAATAATCCTGATAAATGAA TACAGTGATATAAGACTGTGAAGGTGGTAAGTCAGCTGGTCACATACATATTGAAAGAAAAACCCTTGGGTACAGTGGCTCATACCTGTA GTCCCAGCTATTTGGGAGGCTAAGATGGAAGGATCATTTGAGGAATTTGAGTCCAGCCTGGGCAATGTGGTGAGACCCTGTCTGTAAAAG >43140_43140_10_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000534358_AFF4_chr5_132240096_ENST00000378595_length(amino acids)=1912AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDS SSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDT SGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGS RKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEE KELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKN SAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEV -------------------------------------------------------------- >43140_43140_11_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000534358_AFF4_chr5_132262899_ENST00000265343_length(transcript)=12318nt_BP=4109nt CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACGCATTCATGGCCTCCCCCTCTAA CGGCTATTCATACACCATGCAAAACAGAACCTTCCAAATTTCCTTTTCCAACTAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAAC AAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACA GTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAG ATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTG AGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGA ACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTG GGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAA GTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGA AGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACA AAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGT CAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTT CCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAA TGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATC TTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGG CTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAAC CCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGT TGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAA AGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTT CCAGTAGCTCCAAGGAGGTTAAGGAAAAGGCTCCAAGTAGCTCCTCTAACTGTCCTCCATCTGCACCAACTCTTGATTCTTCTAAGCCTC GGAGAACAAAGCTTGTCTTTGATGACAGAAATTATTCAGCAGACCATTATTTACAAGAAGCAAAAAAGCTAAAGCACAATGCAGATGCAT TGTCTGATAGGTTTGAGAAAGCTGTATACTATCTTGATGCTGTGGTATCTTTCATTGAATGTGGGAATGCATTAGAGAAGAATGCTCAGG AATCCAAATCCCCATTCCCTATGTATTCAGAGACGGTGGATCTCATCAAATACACTATGAAGCTAAAGAATTACTTGGCACCAGATGCTA CAGCTGCAGATAAACGACTCACAGTACTTTGCCTGCGATGCGAGTCTTTGCTGTACCTGAGGCTGTTCAAACTGAAGAAGGAAAATGCTC TGAAGTACTCAAAGACACTGACAGAGCACCTGAAGAATTCTTATAATAATTCTCAAGCACCATCGCCTGGCTTGGGAAGCAAAGCTGTGG GGATGCCTTCCCCTGTTTCTCCAAAGCTGTCACCAGGCAATTCAGGAAATTATTCATCTGGGGCCAGTAGTGCTTCTGCAAGTGGTTCTT CAGTGACCATTCCACAGAAGATCCACCAGATGGCAGCCAGCTATGTTCAGGTCACATCCAACTTCCTCTATGCCACCGAAATTTGGGACC AAGCTGAACAGCTTTCCAAAGAGCAAAAAGAATTCTTTGCTGAACTGGATAAAGTAATGGGCCCTCTCATCTTTAATGCAAGCATCATGA CAGATCTAGTTCGTTATACCCGGCAGGGACTGCACTGGCTTCGCCAGGATGCCAAGTTGATATCTTGAACTGAACACATTCTCGTTGCCT CTGATTTTCTCCACAACACTGTGTCACATCACGAAGGAAAACTGCCATAACATACCACCTAGTCGACACTAAGAATGAGGAATAGTTTTC TCCTCGTTGGTTCATGTGTTGTTGTTTTTGATAATCCAAAGCGATCATGTCAGTTGGCCCTTTAATATTTCCAATGTGAAAGATTATTTA AATGCTTTTAAATCTGCAGCACATTGATAAGATGGTTTCCGTGAGCTATGATAAGATTGAAATTCCAGTTGCAATTCATAACTAATGAAT TGAAATTTTATTTATTTTAATTTTTTTAAGTTCCCAGATTGGGGCTAGTTTAAGACTTAGTTATTTCTGCCTATAAATTTACTCTGTTGA ATATTTAGCATAAATTTAATGTAGACATTTTTATTTATATACCTTGGGAGCTTTATTACCTAATATCTTTTTGTGGTAGCTGTTCTAAGA GTAAGAATTGGTTCGTCTAAAATAAGGACATATTCTTTCTACACCTGCTACCTGACCTGATATTTGAAATCTTAACTCCAATTTTATTAT TGTGGAATTTACAGTTAGTATTAAGGATATTCTTCTACACATGAAAAAATCACTTAAATATGAGAAAATGGCATTCTACATGTATGTACT ATGAAATGTGTCTGATTTGGTATGCATTATTTCAAAAACTGTGAATGTGTGTTAATAACACTACAGCAATCACACAGTGACTATAGCTTG CATTTAATGCATTACAAAAGAGGGAGGACAAACTTTCTAGAAGAAGCATTTCATGTTGAAGGGTTTCATAAAAGGACAATCCTGAACGTT ACGGATTTTATTAAAACCATATGTTATTTTTTGTTGCTAATCATTTGACACTTAATCGAAACAGAATAAGTTACTGTGGAAAAAAGGATG ATCCAACTCCTGAGGATTGCCGCCTGTGTGTCTTTAATTGATTATCTTTGATAGTTAGAGTTATTTTTCAGATTTTTCCCCCTCATACTG GATTGTGATGCTCTGATATGAGCATGCAATGACTGATACAGAAATAGGCTGGAGCTTCGGTGTGTGCTTTTGCTATACAGCTTACAGTTC TAATGCCTGATGTAGAGATGATGAATTTCTCCTTTTTAAACCTATCTTCTGTTTACTCCTTTTGCATTATGAAGGCCCTCTTCAATGATG TATGTTTCTGATGGAATCAGAAAATTTCACACTAGAAAAGTGTACCTAACTTGATTCAGTGTGAGCTCTTGGGACAGGGAGTGGAGCCAG GGGTAGAGCTTAAAGAAGCTGGCTCTGTAAGAGTTGTATATCAAAGTACCTTTTGCTACAAGGTGCATATAGAAGTCTAAGATAAGAAAT GTACCCTCTATACTTTATTTTTCATGCCCCTATCATGTTTGGTGTGCCTTAAATCTTACCTTTAAATGAAGACTCTATGGATTGTTTACA AATGAAGTTTTACACTAGGACCAGATCGTCCATACATGATTGGTCTTCTACAATAATAATGTTCAATTCTTTCATTTTAAATCTTTCTTT AGGGTCATATAAAGATTAGTTCTTTCAGAAAAGCTATTGCTTTGGTACATGACTTAGTCTAACCAGTTGGGTAATGCTGCTTTGAAAAAT AGTTTGTCCCTCTCCCCATTCCAAAAATGAATCCATTCAGTCAGAAAAAAAGATTATCCTACTATTTGTAGATGATTGCTAAGGCTTGAA ATAGGAAAGGGGAAAGAAGGGATAGAAAAGTTTCAAGTCCAGTAGTGCAGTGAATCCTTTGTGTTTGAGACTTTTTTACACTTATTTCTG AAGTTAGTGAACTTTCATTGTCCCTGTGGCCTCATATTTATAGAGCTTCTTAACTGTTTTGTACCTCAGATTGTTTTTAGATGTCATTGA AGATTGAGATGTACAAATTATGTTGAATTTAACCTGTTTCTCTTGGAGAAATTGCCTCTGATATCTTTCTAACTTAATCTTAGTGTGTTC TAGGAACAGTTTTCCATAAGAGGACAACTTCTCAATGATCATGATAGTTATTTAGTAAGAAATAATGGTTGTTAATCAAATACATGTTAT GTCTTGTCCTTCTCTGATTTTTCTGACTTGGATTCCTTAATTTGCAGTGATGTCTTAGAAATGGAAAAAGTATCCTCTGGGCTTTCAGAC TTTCAGCAACAACAGCCAGTGGGATACCTCTGAGTTCTTGTGTTCTAGTCTCTTGTATGTCCTGAAAGGCAGCAGGAGCATTTTTGGGGT CACACTGATATTTTGTTAAAGCAGAGTTTCCTGCATGGTTTATGGTGCTGCTCTAATATTTTCTCTTTAAAACTGTGTCAATTTTTGGAG AATGAATTTTTCAACCTTTTCATTGTGGAGGATTTTTCCCACAAGGTAGTAATGGGCAATGGATCAAAATCCTATCATAAATGATTGAAT TTTCAATGTCATAGTGTGTGGAAATACTACTCCCTTTCCTCCATGTCTATCTTCTTAGATGTTCTGTCTTTGTCATCATCTGCTCCAGCA CATACTTTGGACTCCTTTACAGGTGACCTTCCCCCCTCCCTCCTCAATAGGTGTCCTCAGTGTTTTCTAAGCATTTAAAACTGAATTTGA CAAGTGGCTAAAAACTTAGTCTGAGACTTGTACTTAGTATATGGTTAATTATAGAAACAACAACTATTTTAAACAGTTACTCTGTTGACT GCTCTTTATGACTACACTTGTATGCCAGGAGGCAGCAGCCTATACACCATTAGACTCTTTACAAGCAACCAACGAACCAATTGCAGTGGT TGCAGTTGTCACAGTAGTCTTGCCTGGGCCAGACTGGGCTGGGCTGTGGGAAGCATTCCCCTTCAGGGGAGTTTCCACAGCTCAGCCCAG GCTCCAGTCTGGCTAGAGAGCATCCAGCCCATTCCTTGCCTCAGTGCCACCTTTTTCTGGGCAAGTAGCCAAGAAGTGACTTTATATGCA GTGAGTACTTCAGATAAACTTACAGCTACAGCTGCCGAAGAGTGGAGAAGGTTGACCACCATTTATTTAATTCTCTAGTGTAAAAACAAT TGAGAGCAGTGTGCGTGAGCCCACAGACACCTGTGTTTCTGGGAGCTCTGGCAGTGGCGGATTCATAGGCACTTGGGCTGCACTTTGAAT GACACACTTGGCTTTATTAGATTCACTAGTTTTTAAAAAATTGTTGTTCGTTTCTTTTCATTAAAGGTTTAATCAGACAGATCAGACAGC ATAATTTTGTATTTAATGACAGAAACGTTGGTACATTTCTTCATGAATGAGCTTGCATTCTGAAGCAAGAGCCTACAAAAGGCACTTGTT ATAAATGAAAGTTCTGGCTCTAGAGGCCAGTACTCTGGAGTTTCAGAGCAGCCAGTGATTGTTCCAGTCAGTGATGCCTAGTTATATAGA GGAGGAGTACACTGTGCACTCTTCTAGGTGTAAGGGTATGCAACTTTGGATCTTAAAATTCTGTACACATACACACTTTATATATATGTA TGTATGTATGAAAACATGAAATTAGTTTGTCAAATATGTGTGTGTTTAGTATTTTAGCTTAGTGCAACTATTTCCACATTATTTATTAAA TTGATCTAAGACACTTTCTTGTTGACACCTTGAATATTAATGTTCAAGGGTGCAATGTGTATTCCTTTAGATTGTTAAAGCTTAATTACT ATGATTTGTAGTAAATTAACTTTTAAAATGTATTTGAGCCCTTCTGTAGTGTCGTAGGGCTCTTACAGGGTGGGAAAGATTTTAATTTTC CAGTTGCTAATTGAACAGTATGGCCTCATTATATATTTTGATTTATAGGAGTTTGTGTCTGGGTCCCAGGAACATCTACTGGGGATGACT GTTAGGCAGCTTGTGATGATGTTTTTTAAAAAACCTAAGTAACTTGGGGAGACAGAGCATTTCAAACCCATATAGACACCTATCATACCT GTATATCCCCTAATACATGGAACATAAATTTCATTTCAGCTTTATGCATTAATGTATTGAAGAGGCAGGCTTTTTTTCCAGTAATAATAC TGTACATCTAAGGTTGCTATTCAGTAAAACTAATAGAAGAGATAATTATTGAATACCTTGGAATATGTAGTGAGAAGAGGCCAAATTTTT CATGTTTGTGAGCATGTCTTTCAGATACTCGCTAATGGAGAAATTCACTTTAGACCTCTAGACCCCAAAACCAAGTTAGCAAGTGACAAA AAGTAAATTATTAATAGTCTGTAAAGTGGATGCTGGTCTTACAAAGCTCCTATTCACATGAACCCTATGGTTAATTAGAAAGAACTTGCT GTCTCCAGAAAAGGGAATGGAAATAATAACTATGTATCTTCTTTTCATGTAATTTGGTCACAGAATAAGGTATTCAAGTTAAGTCTAATC CAAGTCTTAGAGATCTTTAAGTATCCTAAAATAGCAGCCTAAGTAGTCATCATGTAAAGAAGTTGACTTTCAGGAATGTCAGCATTGACC TCTCCTTGCCACTGTTACTCAGCTAAACATAACTTGCCATTCTTAAAAATAAAAAAGCTCCCACCCAGAAACTCTAGTGATACTCAGTTT TGACCTCTTACTGCTTCCATGTGGGACTTCTTTTCAGCTTTTAACCATTGGAATTTTCTACCTGCTATGTTCCTCTCTGGAAAATATCAA TTTGGAAATGCTGCCTTTCAAATCAATGCCATGATCATCCATATTGTTGAGTTTGTTGTTGGTGTTCCAGAAGTGTCCCCATTTTACAAC TTTATGCACACACCTGGCAAATCATTAACATGAGCATTCAACAGTACTGGGATGGGTGGGGTGGGGGTAGGGGGCTCACCAACAGAACTG GCCAGTTGACATTGCCTGAAAAGGCACCACCTTTAAGGGCCAGTTGTGGGGTTGGTAAGCACAGTTATGAAAATTTCTATCTAGCCTCCG TTTTGAATGGTTTTAAGAAATTTTGTATATGGAGGATGGAAATGCTTATATATTTATTGAAAATCCTTTTATTTGAAATTAAAATTATTT GGTATATAATTGTTTGATATTTGGGGAGGGTTTTGGAGGGGAGATAATGTCACTGATAAATTAAAAGCCTGTTGATTTTGCAGAAAGGTA CTGTTAGTGACTGATAAGGATGCCTTTGTTTTGTACATGAACCAAATCTTTGTTTTACATTTCTTTTATCCAAAATATTTAGGCATCTGA CATTTTCAACCAGAATTTCAATTATATACTGTGATTTTTATTTGTTGCAATACATTACAATTTCAGAGGTACTTTGGGGCTCAAAAGCTA GGATTTCTAAGTCAGTATGTGCATTTCACACGATAAAGCTGTTAATGGTGAGCAAAGTATTATATACTAACTAGATTTTTCCACATCTGT ATAGTATATTATATGTATTTTGTGGTATTGAGAGTATAGAAAGTTTAGAGTGTCAAACATGCGTTTAATGTGTATTTTTAAACAAATTTA TGGCAATTAAAATATTTGGAGACAAGGGTATCACATTTCAATTTGTAAAGATCTTTTTAACTCTACTGTGTCATTAAGATGCTTTGTACA >43140_43140_11_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000534358_AFF4_chr5_132262899_ENST00000265343_length(amino acids)=2204AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCD KTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPA SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPR GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYP ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEK VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNK ETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKKLKHNADALSDRFEKA VYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLFKLKKENALKYSKTLT EHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFLYATEIWDQAEQLSKE -------------------------------------------------------------- >43140_43140_12_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000534358_AFF4_chr5_132262899_ENST00000378595_length(transcript)=6130nt_BP=4109nt CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAGATGACGCATTCATGGCCTCCCCCTCTAA CGGCTATTCATACACCATGCAAAACAGAACCTTCCAAATTTCCTTTTCCAACTAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAAC AAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACA GTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAG ATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTG AGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGA ACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTG GGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAA GTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGA AGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACA AAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGT CAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTT CCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAA TGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATC TTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGG CTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAAC CCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGT TGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAA AGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTT CCAGTAGCTCCAAGGAGGTTAAGGTAAAGTGTTGGGGGCCTGGGGCTTTTGAAAATCATTCAACTTGCCATGTGACTTTTCCAGGGTGAC ACTGTGCTTTGAAATTATTGTAACATCTCAGTAAATATATAGGCCTATGTCTTTTACCCTCTATATGTAATAATCCTGATAAATGAATAC AGTGATATAAGACTGTGAAGGTGGTAAGTCAGCTGGTCACATACATATTGAAAGAAAAACCCTTGGGTACAGTGGCTCATACCTGTAGTC CCAGCTATTTGGGAGGCTAAGATGGAAGGATCATTTGAGGAATTTGAGTCCAGCCTGGGCAATGTGGTGAGACCCTGTCTGTAAAAGAAC >43140_43140_12_KMT2A-AFF4_KMT2A_chr11_118353210_ENST00000534358_AFF4_chr5_132262899_ENST00000378595_length(amino acids)=1941AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEMTHSWPPPLTAIHTPCKTEPSKFPFPTKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDLKLSSSEDSDGEQDCD KTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQLDNWLNKVNPHKVSPA SSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGKKQPKKAEKAAAEEPR GGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSDESESLPPSSQTPKYP ESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNVPEKHTREAQKQASEK VSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRTISQSSSLKSSSNSNK -------------------------------------------------------------- >43140_43140_13_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000354520_AFF4_chr5_132240096_ENST00000265343_length(transcript)=12340nt_BP=4218nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGAGTCTCAGCAG TCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTA AAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCA CACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGT GAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTT GATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAG GAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAA ACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAA AAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGC AGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACA GCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGAT GAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAA GATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTT ATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTG CCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAAC CGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGT GCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACT ATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAG AAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAGGAAAAGGCTCCAAGTAGCTCCTCTAACTGTCCTCCATCTGCACCA ACTCTTGATTCTTCTAAGCCTCGGAGAACAAAGCTTGTCTTTGATGACAGAAATTATTCAGCAGACCATTATTTACAAGAAGCAAAAAAG CTAAAGCACAATGCAGATGCATTGTCTGATAGGTTTGAGAAAGCTGTATACTATCTTGATGCTGTGGTATCTTTCATTGAATGTGGGAAT GCATTAGAGAAGAATGCTCAGGAATCCAAATCCCCATTCCCTATGTATTCAGAGACGGTGGATCTCATCAAATACACTATGAAGCTAAAG AATTACTTGGCACCAGATGCTACAGCTGCAGATAAACGACTCACAGTACTTTGCCTGCGATGCGAGTCTTTGCTGTACCTGAGGCTGTTC AAACTGAAGAAGGAAAATGCTCTGAAGTACTCAAAGACACTGACAGAGCACCTGAAGAATTCTTATAATAATTCTCAAGCACCATCGCCT GGCTTGGGAAGCAAAGCTGTGGGGATGCCTTCCCCTGTTTCTCCAAAGCTGTCACCAGGCAATTCAGGAAATTATTCATCTGGGGCCAGT AGTGCTTCTGCAAGTGGTTCTTCAGTGACCATTCCACAGAAGATCCACCAGATGGCAGCCAGCTATGTTCAGGTCACATCCAACTTCCTC TATGCCACCGAAATTTGGGACCAAGCTGAACAGCTTTCCAAAGAGCAAAAAGAATTCTTTGCTGAACTGGATAAAGTAATGGGCCCTCTC ATCTTTAATGCAAGCATCATGACAGATCTAGTTCGTTATACCCGGCAGGGACTGCACTGGCTTCGCCAGGATGCCAAGTTGATATCTTGA ACTGAACACATTCTCGTTGCCTCTGATTTTCTCCACAACACTGTGTCACATCACGAAGGAAAACTGCCATAACATACCACCTAGTCGACA CTAAGAATGAGGAATAGTTTTCTCCTCGTTGGTTCATGTGTTGTTGTTTTTGATAATCCAAAGCGATCATGTCAGTTGGCCCTTTAATAT TTCCAATGTGAAAGATTATTTAAATGCTTTTAAATCTGCAGCACATTGATAAGATGGTTTCCGTGAGCTATGATAAGATTGAAATTCCAG TTGCAATTCATAACTAATGAATTGAAATTTTATTTATTTTAATTTTTTTAAGTTCCCAGATTGGGGCTAGTTTAAGACTTAGTTATTTCT GCCTATAAATTTACTCTGTTGAATATTTAGCATAAATTTAATGTAGACATTTTTATTTATATACCTTGGGAGCTTTATTACCTAATATCT TTTTGTGGTAGCTGTTCTAAGAGTAAGAATTGGTTCGTCTAAAATAAGGACATATTCTTTCTACACCTGCTACCTGACCTGATATTTGAA ATCTTAACTCCAATTTTATTATTGTGGAATTTACAGTTAGTATTAAGGATATTCTTCTACACATGAAAAAATCACTTAAATATGAGAAAA TGGCATTCTACATGTATGTACTATGAAATGTGTCTGATTTGGTATGCATTATTTCAAAAACTGTGAATGTGTGTTAATAACACTACAGCA ATCACACAGTGACTATAGCTTGCATTTAATGCATTACAAAAGAGGGAGGACAAACTTTCTAGAAGAAGCATTTCATGTTGAAGGGTTTCA TAAAAGGACAATCCTGAACGTTACGGATTTTATTAAAACCATATGTTATTTTTTGTTGCTAATCATTTGACACTTAATCGAAACAGAATA AGTTACTGTGGAAAAAAGGATGATCCAACTCCTGAGGATTGCCGCCTGTGTGTCTTTAATTGATTATCTTTGATAGTTAGAGTTATTTTT CAGATTTTTCCCCCTCATACTGGATTGTGATGCTCTGATATGAGCATGCAATGACTGATACAGAAATAGGCTGGAGCTTCGGTGTGTGCT TTTGCTATACAGCTTACAGTTCTAATGCCTGATGTAGAGATGATGAATTTCTCCTTTTTAAACCTATCTTCTGTTTACTCCTTTTGCATT ATGAAGGCCCTCTTCAATGATGTATGTTTCTGATGGAATCAGAAAATTTCACACTAGAAAAGTGTACCTAACTTGATTCAGTGTGAGCTC TTGGGACAGGGAGTGGAGCCAGGGGTAGAGCTTAAAGAAGCTGGCTCTGTAAGAGTTGTATATCAAAGTACCTTTTGCTACAAGGTGCAT ATAGAAGTCTAAGATAAGAAATGTACCCTCTATACTTTATTTTTCATGCCCCTATCATGTTTGGTGTGCCTTAAATCTTACCTTTAAATG AAGACTCTATGGATTGTTTACAAATGAAGTTTTACACTAGGACCAGATCGTCCATACATGATTGGTCTTCTACAATAATAATGTTCAATT CTTTCATTTTAAATCTTTCTTTAGGGTCATATAAAGATTAGTTCTTTCAGAAAAGCTATTGCTTTGGTACATGACTTAGTCTAACCAGTT GGGTAATGCTGCTTTGAAAAATAGTTTGTCCCTCTCCCCATTCCAAAAATGAATCCATTCAGTCAGAAAAAAAGATTATCCTACTATTTG TAGATGATTGCTAAGGCTTGAAATAGGAAAGGGGAAAGAAGGGATAGAAAAGTTTCAAGTCCAGTAGTGCAGTGAATCCTTTGTGTTTGA GACTTTTTTACACTTATTTCTGAAGTTAGTGAACTTTCATTGTCCCTGTGGCCTCATATTTATAGAGCTTCTTAACTGTTTTGTACCTCA GATTGTTTTTAGATGTCATTGAAGATTGAGATGTACAAATTATGTTGAATTTAACCTGTTTCTCTTGGAGAAATTGCCTCTGATATCTTT CTAACTTAATCTTAGTGTGTTCTAGGAACAGTTTTCCATAAGAGGACAACTTCTCAATGATCATGATAGTTATTTAGTAAGAAATAATGG TTGTTAATCAAATACATGTTATGTCTTGTCCTTCTCTGATTTTTCTGACTTGGATTCCTTAATTTGCAGTGATGTCTTAGAAATGGAAAA AGTATCCTCTGGGCTTTCAGACTTTCAGCAACAACAGCCAGTGGGATACCTCTGAGTTCTTGTGTTCTAGTCTCTTGTATGTCCTGAAAG GCAGCAGGAGCATTTTTGGGGTCACACTGATATTTTGTTAAAGCAGAGTTTCCTGCATGGTTTATGGTGCTGCTCTAATATTTTCTCTTT AAAACTGTGTCAATTTTTGGAGAATGAATTTTTCAACCTTTTCATTGTGGAGGATTTTTCCCACAAGGTAGTAATGGGCAATGGATCAAA ATCCTATCATAAATGATTGAATTTTCAATGTCATAGTGTGTGGAAATACTACTCCCTTTCCTCCATGTCTATCTTCTTAGATGTTCTGTC TTTGTCATCATCTGCTCCAGCACATACTTTGGACTCCTTTACAGGTGACCTTCCCCCCTCCCTCCTCAATAGGTGTCCTCAGTGTTTTCT AAGCATTTAAAACTGAATTTGACAAGTGGCTAAAAACTTAGTCTGAGACTTGTACTTAGTATATGGTTAATTATAGAAACAACAACTATT TTAAACAGTTACTCTGTTGACTGCTCTTTATGACTACACTTGTATGCCAGGAGGCAGCAGCCTATACACCATTAGACTCTTTACAAGCAA CCAACGAACCAATTGCAGTGGTTGCAGTTGTCACAGTAGTCTTGCCTGGGCCAGACTGGGCTGGGCTGTGGGAAGCATTCCCCTTCAGGG GAGTTTCCACAGCTCAGCCCAGGCTCCAGTCTGGCTAGAGAGCATCCAGCCCATTCCTTGCCTCAGTGCCACCTTTTTCTGGGCAAGTAG CCAAGAAGTGACTTTATATGCAGTGAGTACTTCAGATAAACTTACAGCTACAGCTGCCGAAGAGTGGAGAAGGTTGACCACCATTTATTT AATTCTCTAGTGTAAAAACAATTGAGAGCAGTGTGCGTGAGCCCACAGACACCTGTGTTTCTGGGAGCTCTGGCAGTGGCGGATTCATAG GCACTTGGGCTGCACTTTGAATGACACACTTGGCTTTATTAGATTCACTAGTTTTTAAAAAATTGTTGTTCGTTTCTTTTCATTAAAGGT TTAATCAGACAGATCAGACAGCATAATTTTGTATTTAATGACAGAAACGTTGGTACATTTCTTCATGAATGAGCTTGCATTCTGAAGCAA GAGCCTACAAAAGGCACTTGTTATAAATGAAAGTTCTGGCTCTAGAGGCCAGTACTCTGGAGTTTCAGAGCAGCCAGTGATTGTTCCAGT CAGTGATGCCTAGTTATATAGAGGAGGAGTACACTGTGCACTCTTCTAGGTGTAAGGGTATGCAACTTTGGATCTTAAAATTCTGTACAC ATACACACTTTATATATATGTATGTATGTATGAAAACATGAAATTAGTTTGTCAAATATGTGTGTGTTTAGTATTTTAGCTTAGTGCAAC TATTTCCACATTATTTATTAAATTGATCTAAGACACTTTCTTGTTGACACCTTGAATATTAATGTTCAAGGGTGCAATGTGTATTCCTTT AGATTGTTAAAGCTTAATTACTATGATTTGTAGTAAATTAACTTTTAAAATGTATTTGAGCCCTTCTGTAGTGTCGTAGGGCTCTTACAG GGTGGGAAAGATTTTAATTTTCCAGTTGCTAATTGAACAGTATGGCCTCATTATATATTTTGATTTATAGGAGTTTGTGTCTGGGTCCCA GGAACATCTACTGGGGATGACTGTTAGGCAGCTTGTGATGATGTTTTTTAAAAAACCTAAGTAACTTGGGGAGACAGAGCATTTCAAACC CATATAGACACCTATCATACCTGTATATCCCCTAATACATGGAACATAAATTTCATTTCAGCTTTATGCATTAATGTATTGAAGAGGCAG GCTTTTTTTCCAGTAATAATACTGTACATCTAAGGTTGCTATTCAGTAAAACTAATAGAAGAGATAATTATTGAATACCTTGGAATATGT AGTGAGAAGAGGCCAAATTTTTCATGTTTGTGAGCATGTCTTTCAGATACTCGCTAATGGAGAAATTCACTTTAGACCTCTAGACCCCAA AACCAAGTTAGCAAGTGACAAAAAGTAAATTATTAATAGTCTGTAAAGTGGATGCTGGTCTTACAAAGCTCCTATTCACATGAACCCTAT GGTTAATTAGAAAGAACTTGCTGTCTCCAGAAAAGGGAATGGAAATAATAACTATGTATCTTCTTTTCATGTAATTTGGTCACAGAATAA GGTATTCAAGTTAAGTCTAATCCAAGTCTTAGAGATCTTTAAGTATCCTAAAATAGCAGCCTAAGTAGTCATCATGTAAAGAAGTTGACT TTCAGGAATGTCAGCATTGACCTCTCCTTGCCACTGTTACTCAGCTAAACATAACTTGCCATTCTTAAAAATAAAAAAGCTCCCACCCAG AAACTCTAGTGATACTCAGTTTTGACCTCTTACTGCTTCCATGTGGGACTTCTTTTCAGCTTTTAACCATTGGAATTTTCTACCTGCTAT GTTCCTCTCTGGAAAATATCAATTTGGAAATGCTGCCTTTCAAATCAATGCCATGATCATCCATATTGTTGAGTTTGTTGTTGGTGTTCC AGAAGTGTCCCCATTTTACAACTTTATGCACACACCTGGCAAATCATTAACATGAGCATTCAACAGTACTGGGATGGGTGGGGTGGGGGT AGGGGGCTCACCAACAGAACTGGCCAGTTGACATTGCCTGAAAAGGCACCACCTTTAAGGGCCAGTTGTGGGGTTGGTAAGCACAGTTAT GAAAATTTCTATCTAGCCTCCGTTTTGAATGGTTTTAAGAAATTTTGTATATGGAGGATGGAAATGCTTATATATTTATTGAAAATCCTT TTATTTGAAATTAAAATTATTTGGTATATAATTGTTTGATATTTGGGGAGGGTTTTGGAGGGGAGATAATGTCACTGATAAATTAAAAGC CTGTTGATTTTGCAGAAAGGTACTGTTAGTGACTGATAAGGATGCCTTTGTTTTGTACATGAACCAAATCTTTGTTTTACATTTCTTTTA TCCAAAATATTTAGGCATCTGACATTTTCAACCAGAATTTCAATTATATACTGTGATTTTTATTTGTTGCAATACATTACAATTTCAGAG GTACTTTGGGGCTCAAAAGCTAGGATTTCTAAGTCAGTATGTGCATTTCACACGATAAAGCTGTTAATGGTGAGCAAAGTATTATATACT AACTAGATTTTTCCACATCTGTATAGTATATTATATGTATTTTGTGGTATTGAGAGTATAGAAAGTTTAGAGTGTCAAACATGCGTTTAA TGTGTATTTTTAAACAAATTTATGGCAATTAAAATATTTGGAGACAAGGGTATCACATTTCAATTTGTAAAGATCTTTTTAACTCTACTG TGTCATTAAGATGCTTTGTACAATGCCAAACCATAGTTGGAGAAACTAAGTTTAATAAATATCAAATAGATTTTCTGTATTAAAGTTACT >43140_43140_13_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000354520_AFF4_chr5_132240096_ENST00000265343_length(amino acids)=2219AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDL KLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQL DNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK KQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSD ESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNV PEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRT ISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKK LKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLF KLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFL -------------------------------------------------------------- >43140_43140_14_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000354520_AFF4_chr5_132240096_ENST00000378595_length(transcript)=6152nt_BP=4218nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGAGTCTCAGCAG TCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTA AAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCA CACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGT GAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTT GATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAG GAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAA ACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAA AAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGC AGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACA GCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGAT GAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAA GATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTT ATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTG CCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAAC CGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGT GCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACT ATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAG AAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAGGTAAAGTGTTGGGGGCCTGGGGCTTTTGAAAATCATTCAACTTGC CATGTGACTTTTCCAGGGTGACACTGTGCTTTGAAATTATTGTAACATCTCAGTAAATATATAGGCCTATGTCTTTTACCCTCTATATGT AATAATCCTGATAAATGAATACAGTGATATAAGACTGTGAAGGTGGTAAGTCAGCTGGTCACATACATATTGAAAGAAAAACCCTTGGGT ACAGTGGCTCATACCTGTAGTCCCAGCTATTTGGGAGGCTAAGATGGAAGGATCATTTGAGGAATTTGAGTCCAGCCTGGGCAATGTGGT >43140_43140_14_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000354520_AFF4_chr5_132240096_ENST00000378595_length(amino acids)=1956AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDL KLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQL DNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK KQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSD ESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNV PEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRT -------------------------------------------------------------- >43140_43140_15_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000389506_AFF4_chr5_132240096_ENST00000265343_length(transcript)=12340nt_BP=4218nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGAGTCTCAGCAG TCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTA AAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCA CACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGT GAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTT GATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAG GAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAA ACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAA AAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGC AGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACA GCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGAT GAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAA GATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTT ATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTG CCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAAC CGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGT GCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACT ATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAG AAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAGGAAAAGGCTCCAAGTAGCTCCTCTAACTGTCCTCCATCTGCACCA ACTCTTGATTCTTCTAAGCCTCGGAGAACAAAGCTTGTCTTTGATGACAGAAATTATTCAGCAGACCATTATTTACAAGAAGCAAAAAAG CTAAAGCACAATGCAGATGCATTGTCTGATAGGTTTGAGAAAGCTGTATACTATCTTGATGCTGTGGTATCTTTCATTGAATGTGGGAAT GCATTAGAGAAGAATGCTCAGGAATCCAAATCCCCATTCCCTATGTATTCAGAGACGGTGGATCTCATCAAATACACTATGAAGCTAAAG AATTACTTGGCACCAGATGCTACAGCTGCAGATAAACGACTCACAGTACTTTGCCTGCGATGCGAGTCTTTGCTGTACCTGAGGCTGTTC AAACTGAAGAAGGAAAATGCTCTGAAGTACTCAAAGACACTGACAGAGCACCTGAAGAATTCTTATAATAATTCTCAAGCACCATCGCCT GGCTTGGGAAGCAAAGCTGTGGGGATGCCTTCCCCTGTTTCTCCAAAGCTGTCACCAGGCAATTCAGGAAATTATTCATCTGGGGCCAGT AGTGCTTCTGCAAGTGGTTCTTCAGTGACCATTCCACAGAAGATCCACCAGATGGCAGCCAGCTATGTTCAGGTCACATCCAACTTCCTC TATGCCACCGAAATTTGGGACCAAGCTGAACAGCTTTCCAAAGAGCAAAAAGAATTCTTTGCTGAACTGGATAAAGTAATGGGCCCTCTC ATCTTTAATGCAAGCATCATGACAGATCTAGTTCGTTATACCCGGCAGGGACTGCACTGGCTTCGCCAGGATGCCAAGTTGATATCTTGA ACTGAACACATTCTCGTTGCCTCTGATTTTCTCCACAACACTGTGTCACATCACGAAGGAAAACTGCCATAACATACCACCTAGTCGACA CTAAGAATGAGGAATAGTTTTCTCCTCGTTGGTTCATGTGTTGTTGTTTTTGATAATCCAAAGCGATCATGTCAGTTGGCCCTTTAATAT TTCCAATGTGAAAGATTATTTAAATGCTTTTAAATCTGCAGCACATTGATAAGATGGTTTCCGTGAGCTATGATAAGATTGAAATTCCAG TTGCAATTCATAACTAATGAATTGAAATTTTATTTATTTTAATTTTTTTAAGTTCCCAGATTGGGGCTAGTTTAAGACTTAGTTATTTCT GCCTATAAATTTACTCTGTTGAATATTTAGCATAAATTTAATGTAGACATTTTTATTTATATACCTTGGGAGCTTTATTACCTAATATCT TTTTGTGGTAGCTGTTCTAAGAGTAAGAATTGGTTCGTCTAAAATAAGGACATATTCTTTCTACACCTGCTACCTGACCTGATATTTGAA ATCTTAACTCCAATTTTATTATTGTGGAATTTACAGTTAGTATTAAGGATATTCTTCTACACATGAAAAAATCACTTAAATATGAGAAAA TGGCATTCTACATGTATGTACTATGAAATGTGTCTGATTTGGTATGCATTATTTCAAAAACTGTGAATGTGTGTTAATAACACTACAGCA ATCACACAGTGACTATAGCTTGCATTTAATGCATTACAAAAGAGGGAGGACAAACTTTCTAGAAGAAGCATTTCATGTTGAAGGGTTTCA TAAAAGGACAATCCTGAACGTTACGGATTTTATTAAAACCATATGTTATTTTTTGTTGCTAATCATTTGACACTTAATCGAAACAGAATA AGTTACTGTGGAAAAAAGGATGATCCAACTCCTGAGGATTGCCGCCTGTGTGTCTTTAATTGATTATCTTTGATAGTTAGAGTTATTTTT CAGATTTTTCCCCCTCATACTGGATTGTGATGCTCTGATATGAGCATGCAATGACTGATACAGAAATAGGCTGGAGCTTCGGTGTGTGCT TTTGCTATACAGCTTACAGTTCTAATGCCTGATGTAGAGATGATGAATTTCTCCTTTTTAAACCTATCTTCTGTTTACTCCTTTTGCATT ATGAAGGCCCTCTTCAATGATGTATGTTTCTGATGGAATCAGAAAATTTCACACTAGAAAAGTGTACCTAACTTGATTCAGTGTGAGCTC TTGGGACAGGGAGTGGAGCCAGGGGTAGAGCTTAAAGAAGCTGGCTCTGTAAGAGTTGTATATCAAAGTACCTTTTGCTACAAGGTGCAT ATAGAAGTCTAAGATAAGAAATGTACCCTCTATACTTTATTTTTCATGCCCCTATCATGTTTGGTGTGCCTTAAATCTTACCTTTAAATG AAGACTCTATGGATTGTTTACAAATGAAGTTTTACACTAGGACCAGATCGTCCATACATGATTGGTCTTCTACAATAATAATGTTCAATT CTTTCATTTTAAATCTTTCTTTAGGGTCATATAAAGATTAGTTCTTTCAGAAAAGCTATTGCTTTGGTACATGACTTAGTCTAACCAGTT GGGTAATGCTGCTTTGAAAAATAGTTTGTCCCTCTCCCCATTCCAAAAATGAATCCATTCAGTCAGAAAAAAAGATTATCCTACTATTTG TAGATGATTGCTAAGGCTTGAAATAGGAAAGGGGAAAGAAGGGATAGAAAAGTTTCAAGTCCAGTAGTGCAGTGAATCCTTTGTGTTTGA GACTTTTTTACACTTATTTCTGAAGTTAGTGAACTTTCATTGTCCCTGTGGCCTCATATTTATAGAGCTTCTTAACTGTTTTGTACCTCA GATTGTTTTTAGATGTCATTGAAGATTGAGATGTACAAATTATGTTGAATTTAACCTGTTTCTCTTGGAGAAATTGCCTCTGATATCTTT CTAACTTAATCTTAGTGTGTTCTAGGAACAGTTTTCCATAAGAGGACAACTTCTCAATGATCATGATAGTTATTTAGTAAGAAATAATGG TTGTTAATCAAATACATGTTATGTCTTGTCCTTCTCTGATTTTTCTGACTTGGATTCCTTAATTTGCAGTGATGTCTTAGAAATGGAAAA AGTATCCTCTGGGCTTTCAGACTTTCAGCAACAACAGCCAGTGGGATACCTCTGAGTTCTTGTGTTCTAGTCTCTTGTATGTCCTGAAAG GCAGCAGGAGCATTTTTGGGGTCACACTGATATTTTGTTAAAGCAGAGTTTCCTGCATGGTTTATGGTGCTGCTCTAATATTTTCTCTTT AAAACTGTGTCAATTTTTGGAGAATGAATTTTTCAACCTTTTCATTGTGGAGGATTTTTCCCACAAGGTAGTAATGGGCAATGGATCAAA ATCCTATCATAAATGATTGAATTTTCAATGTCATAGTGTGTGGAAATACTACTCCCTTTCCTCCATGTCTATCTTCTTAGATGTTCTGTC TTTGTCATCATCTGCTCCAGCACATACTTTGGACTCCTTTACAGGTGACCTTCCCCCCTCCCTCCTCAATAGGTGTCCTCAGTGTTTTCT AAGCATTTAAAACTGAATTTGACAAGTGGCTAAAAACTTAGTCTGAGACTTGTACTTAGTATATGGTTAATTATAGAAACAACAACTATT TTAAACAGTTACTCTGTTGACTGCTCTTTATGACTACACTTGTATGCCAGGAGGCAGCAGCCTATACACCATTAGACTCTTTACAAGCAA CCAACGAACCAATTGCAGTGGTTGCAGTTGTCACAGTAGTCTTGCCTGGGCCAGACTGGGCTGGGCTGTGGGAAGCATTCCCCTTCAGGG GAGTTTCCACAGCTCAGCCCAGGCTCCAGTCTGGCTAGAGAGCATCCAGCCCATTCCTTGCCTCAGTGCCACCTTTTTCTGGGCAAGTAG CCAAGAAGTGACTTTATATGCAGTGAGTACTTCAGATAAACTTACAGCTACAGCTGCCGAAGAGTGGAGAAGGTTGACCACCATTTATTT AATTCTCTAGTGTAAAAACAATTGAGAGCAGTGTGCGTGAGCCCACAGACACCTGTGTTTCTGGGAGCTCTGGCAGTGGCGGATTCATAG GCACTTGGGCTGCACTTTGAATGACACACTTGGCTTTATTAGATTCACTAGTTTTTAAAAAATTGTTGTTCGTTTCTTTTCATTAAAGGT TTAATCAGACAGATCAGACAGCATAATTTTGTATTTAATGACAGAAACGTTGGTACATTTCTTCATGAATGAGCTTGCATTCTGAAGCAA GAGCCTACAAAAGGCACTTGTTATAAATGAAAGTTCTGGCTCTAGAGGCCAGTACTCTGGAGTTTCAGAGCAGCCAGTGATTGTTCCAGT CAGTGATGCCTAGTTATATAGAGGAGGAGTACACTGTGCACTCTTCTAGGTGTAAGGGTATGCAACTTTGGATCTTAAAATTCTGTACAC ATACACACTTTATATATATGTATGTATGTATGAAAACATGAAATTAGTTTGTCAAATATGTGTGTGTTTAGTATTTTAGCTTAGTGCAAC TATTTCCACATTATTTATTAAATTGATCTAAGACACTTTCTTGTTGACACCTTGAATATTAATGTTCAAGGGTGCAATGTGTATTCCTTT AGATTGTTAAAGCTTAATTACTATGATTTGTAGTAAATTAACTTTTAAAATGTATTTGAGCCCTTCTGTAGTGTCGTAGGGCTCTTACAG GGTGGGAAAGATTTTAATTTTCCAGTTGCTAATTGAACAGTATGGCCTCATTATATATTTTGATTTATAGGAGTTTGTGTCTGGGTCCCA GGAACATCTACTGGGGATGACTGTTAGGCAGCTTGTGATGATGTTTTTTAAAAAACCTAAGTAACTTGGGGAGACAGAGCATTTCAAACC CATATAGACACCTATCATACCTGTATATCCCCTAATACATGGAACATAAATTTCATTTCAGCTTTATGCATTAATGTATTGAAGAGGCAG GCTTTTTTTCCAGTAATAATACTGTACATCTAAGGTTGCTATTCAGTAAAACTAATAGAAGAGATAATTATTGAATACCTTGGAATATGT AGTGAGAAGAGGCCAAATTTTTCATGTTTGTGAGCATGTCTTTCAGATACTCGCTAATGGAGAAATTCACTTTAGACCTCTAGACCCCAA AACCAAGTTAGCAAGTGACAAAAAGTAAATTATTAATAGTCTGTAAAGTGGATGCTGGTCTTACAAAGCTCCTATTCACATGAACCCTAT GGTTAATTAGAAAGAACTTGCTGTCTCCAGAAAAGGGAATGGAAATAATAACTATGTATCTTCTTTTCATGTAATTTGGTCACAGAATAA GGTATTCAAGTTAAGTCTAATCCAAGTCTTAGAGATCTTTAAGTATCCTAAAATAGCAGCCTAAGTAGTCATCATGTAAAGAAGTTGACT TTCAGGAATGTCAGCATTGACCTCTCCTTGCCACTGTTACTCAGCTAAACATAACTTGCCATTCTTAAAAATAAAAAAGCTCCCACCCAG AAACTCTAGTGATACTCAGTTTTGACCTCTTACTGCTTCCATGTGGGACTTCTTTTCAGCTTTTAACCATTGGAATTTTCTACCTGCTAT GTTCCTCTCTGGAAAATATCAATTTGGAAATGCTGCCTTTCAAATCAATGCCATGATCATCCATATTGTTGAGTTTGTTGTTGGTGTTCC AGAAGTGTCCCCATTTTACAACTTTATGCACACACCTGGCAAATCATTAACATGAGCATTCAACAGTACTGGGATGGGTGGGGTGGGGGT AGGGGGCTCACCAACAGAACTGGCCAGTTGACATTGCCTGAAAAGGCACCACCTTTAAGGGCCAGTTGTGGGGTTGGTAAGCACAGTTAT GAAAATTTCTATCTAGCCTCCGTTTTGAATGGTTTTAAGAAATTTTGTATATGGAGGATGGAAATGCTTATATATTTATTGAAAATCCTT TTATTTGAAATTAAAATTATTTGGTATATAATTGTTTGATATTTGGGGAGGGTTTTGGAGGGGAGATAATGTCACTGATAAATTAAAAGC CTGTTGATTTTGCAGAAAGGTACTGTTAGTGACTGATAAGGATGCCTTTGTTTTGTACATGAACCAAATCTTTGTTTTACATTTCTTTTA TCCAAAATATTTAGGCATCTGACATTTTCAACCAGAATTTCAATTATATACTGTGATTTTTATTTGTTGCAATACATTACAATTTCAGAG GTACTTTGGGGCTCAAAAGCTAGGATTTCTAAGTCAGTATGTGCATTTCACACGATAAAGCTGTTAATGGTGAGCAAAGTATTATATACT AACTAGATTTTTCCACATCTGTATAGTATATTATATGTATTTTGTGGTATTGAGAGTATAGAAAGTTTAGAGTGTCAAACATGCGTTTAA TGTGTATTTTTAAACAAATTTATGGCAATTAAAATATTTGGAGACAAGGGTATCACATTTCAATTTGTAAAGATCTTTTTAACTCTACTG TGTCATTAAGATGCTTTGTACAATGCCAAACCATAGTTGGAGAAACTAAGTTTAATAAATATCAAATAGATTTTCTGTATTAAAGTTACT >43140_43140_15_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000389506_AFF4_chr5_132240096_ENST00000265343_length(amino acids)=2219AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDL KLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQL DNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK KQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSD ESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNV PEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRT ISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKK LKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLF KLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFL -------------------------------------------------------------- >43140_43140_16_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000389506_AFF4_chr5_132240096_ENST00000378595_length(transcript)=6152nt_BP=4218nt ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGAATGCAGGCACTTTGAACATCCTC AGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAGTGGACTTTAAGGAGTCTCAGCAG TCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTAAATCTATGTTAAAAGATGACTTA AAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACACCAGGAAGTAACTCTGAACCTTCA CACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCAGCTCTGGATCTGACTCAGAGAGT GAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCCCGCCAACAAACAAATGGCAACTT GATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCCCATCATCTCAAGGCTACAAAAAG GAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCGCTACTCCGGGACGAGACTCCAAA ACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAACACAGAGAAGAACTGTAGGCAAA AAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTGAAACCCCTGTAGACTTGGCTAGC AGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGTCTAAGTCTTCCCCTCGACCTACA GCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAGATACCTCATCCTCAGATTCAGAT GAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTAAACCCTCCTCAGTGGAGGAAGAA GATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTGAGCCTGATGACAGGTACCCACTT ATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGCCCAAGGGGGAAAAGAAAAATGTG CCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGAAGCATAAGAATGAAGATGATAAC CGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCAACAGAGAGTCATCTAAGCAGAGT GCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAGAGCATGGCTCTCGGAAGAGGACT ATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAAACAGTTCCTCCACATCAAAGCAG AAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAGGTAAAGTGTTGGGGGCCTGGGGCTTTTGAAAATCATTCAACTTGC CATGTGACTTTTCCAGGGTGACACTGTGCTTTGAAATTATTGTAACATCTCAGTAAATATATAGGCCTATGTCTTTTACCCTCTATATGT AATAATCCTGATAAATGAATACAGTGATATAAGACTGTGAAGGTGGTAAGTCAGCTGGTCACATACATATTGAAAGAAAAACCCTTGGGT ACAGTGGCTCATACCTGTAGTCCCAGCTATTTGGGAGGCTAAGATGGAAGGATCATTTGAGGAATTTGAGTCCAGCCTGGGCAATGTGGT >43140_43140_16_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000389506_AFF4_chr5_132240096_ENST00000378595_length(amino acids)=1956AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDL KLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQL DNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK KQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSD ESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNV PEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRT -------------------------------------------------------------- >43140_43140_17_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000534358_AFF4_chr5_132240096_ENST00000265343_length(transcript)=12363nt_BP=4241nt CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGA ATGCAGGCACTTTGAACATCCTCAGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAG TGGACTTTAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTA AATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACAC CAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCA GCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCC CGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCC CATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCG CTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAA CACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTG AAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGT CTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAG ATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTA AACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTG AGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGC CCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGA AGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCA ACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAG AGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAA ACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAGGAAAAGGCTCCAAGTAGCTCCT CTAACTGTCCTCCATCTGCACCAACTCTTGATTCTTCTAAGCCTCGGAGAACAAAGCTTGTCTTTGATGACAGAAATTATTCAGCAGACC ATTATTTACAAGAAGCAAAAAAGCTAAAGCACAATGCAGATGCATTGTCTGATAGGTTTGAGAAAGCTGTATACTATCTTGATGCTGTGG TATCTTTCATTGAATGTGGGAATGCATTAGAGAAGAATGCTCAGGAATCCAAATCCCCATTCCCTATGTATTCAGAGACGGTGGATCTCA TCAAATACACTATGAAGCTAAAGAATTACTTGGCACCAGATGCTACAGCTGCAGATAAACGACTCACAGTACTTTGCCTGCGATGCGAGT CTTTGCTGTACCTGAGGCTGTTCAAACTGAAGAAGGAAAATGCTCTGAAGTACTCAAAGACACTGACAGAGCACCTGAAGAATTCTTATA ATAATTCTCAAGCACCATCGCCTGGCTTGGGAAGCAAAGCTGTGGGGATGCCTTCCCCTGTTTCTCCAAAGCTGTCACCAGGCAATTCAG GAAATTATTCATCTGGGGCCAGTAGTGCTTCTGCAAGTGGTTCTTCAGTGACCATTCCACAGAAGATCCACCAGATGGCAGCCAGCTATG TTCAGGTCACATCCAACTTCCTCTATGCCACCGAAATTTGGGACCAAGCTGAACAGCTTTCCAAAGAGCAAAAAGAATTCTTTGCTGAAC TGGATAAAGTAATGGGCCCTCTCATCTTTAATGCAAGCATCATGACAGATCTAGTTCGTTATACCCGGCAGGGACTGCACTGGCTTCGCC AGGATGCCAAGTTGATATCTTGAACTGAACACATTCTCGTTGCCTCTGATTTTCTCCACAACACTGTGTCACATCACGAAGGAAAACTGC CATAACATACCACCTAGTCGACACTAAGAATGAGGAATAGTTTTCTCCTCGTTGGTTCATGTGTTGTTGTTTTTGATAATCCAAAGCGAT CATGTCAGTTGGCCCTTTAATATTTCCAATGTGAAAGATTATTTAAATGCTTTTAAATCTGCAGCACATTGATAAGATGGTTTCCGTGAG CTATGATAAGATTGAAATTCCAGTTGCAATTCATAACTAATGAATTGAAATTTTATTTATTTTAATTTTTTTAAGTTCCCAGATTGGGGC TAGTTTAAGACTTAGTTATTTCTGCCTATAAATTTACTCTGTTGAATATTTAGCATAAATTTAATGTAGACATTTTTATTTATATACCTT GGGAGCTTTATTACCTAATATCTTTTTGTGGTAGCTGTTCTAAGAGTAAGAATTGGTTCGTCTAAAATAAGGACATATTCTTTCTACACC TGCTACCTGACCTGATATTTGAAATCTTAACTCCAATTTTATTATTGTGGAATTTACAGTTAGTATTAAGGATATTCTTCTACACATGAA AAAATCACTTAAATATGAGAAAATGGCATTCTACATGTATGTACTATGAAATGTGTCTGATTTGGTATGCATTATTTCAAAAACTGTGAA TGTGTGTTAATAACACTACAGCAATCACACAGTGACTATAGCTTGCATTTAATGCATTACAAAAGAGGGAGGACAAACTTTCTAGAAGAA GCATTTCATGTTGAAGGGTTTCATAAAAGGACAATCCTGAACGTTACGGATTTTATTAAAACCATATGTTATTTTTTGTTGCTAATCATT TGACACTTAATCGAAACAGAATAAGTTACTGTGGAAAAAAGGATGATCCAACTCCTGAGGATTGCCGCCTGTGTGTCTTTAATTGATTAT CTTTGATAGTTAGAGTTATTTTTCAGATTTTTCCCCCTCATACTGGATTGTGATGCTCTGATATGAGCATGCAATGACTGATACAGAAAT AGGCTGGAGCTTCGGTGTGTGCTTTTGCTATACAGCTTACAGTTCTAATGCCTGATGTAGAGATGATGAATTTCTCCTTTTTAAACCTAT CTTCTGTTTACTCCTTTTGCATTATGAAGGCCCTCTTCAATGATGTATGTTTCTGATGGAATCAGAAAATTTCACACTAGAAAAGTGTAC CTAACTTGATTCAGTGTGAGCTCTTGGGACAGGGAGTGGAGCCAGGGGTAGAGCTTAAAGAAGCTGGCTCTGTAAGAGTTGTATATCAAA GTACCTTTTGCTACAAGGTGCATATAGAAGTCTAAGATAAGAAATGTACCCTCTATACTTTATTTTTCATGCCCCTATCATGTTTGGTGT GCCTTAAATCTTACCTTTAAATGAAGACTCTATGGATTGTTTACAAATGAAGTTTTACACTAGGACCAGATCGTCCATACATGATTGGTC TTCTACAATAATAATGTTCAATTCTTTCATTTTAAATCTTTCTTTAGGGTCATATAAAGATTAGTTCTTTCAGAAAAGCTATTGCTTTGG TACATGACTTAGTCTAACCAGTTGGGTAATGCTGCTTTGAAAAATAGTTTGTCCCTCTCCCCATTCCAAAAATGAATCCATTCAGTCAGA AAAAAAGATTATCCTACTATTTGTAGATGATTGCTAAGGCTTGAAATAGGAAAGGGGAAAGAAGGGATAGAAAAGTTTCAAGTCCAGTAG TGCAGTGAATCCTTTGTGTTTGAGACTTTTTTACACTTATTTCTGAAGTTAGTGAACTTTCATTGTCCCTGTGGCCTCATATTTATAGAG CTTCTTAACTGTTTTGTACCTCAGATTGTTTTTAGATGTCATTGAAGATTGAGATGTACAAATTATGTTGAATTTAACCTGTTTCTCTTG GAGAAATTGCCTCTGATATCTTTCTAACTTAATCTTAGTGTGTTCTAGGAACAGTTTTCCATAAGAGGACAACTTCTCAATGATCATGAT AGTTATTTAGTAAGAAATAATGGTTGTTAATCAAATACATGTTATGTCTTGTCCTTCTCTGATTTTTCTGACTTGGATTCCTTAATTTGC AGTGATGTCTTAGAAATGGAAAAAGTATCCTCTGGGCTTTCAGACTTTCAGCAACAACAGCCAGTGGGATACCTCTGAGTTCTTGTGTTC TAGTCTCTTGTATGTCCTGAAAGGCAGCAGGAGCATTTTTGGGGTCACACTGATATTTTGTTAAAGCAGAGTTTCCTGCATGGTTTATGG TGCTGCTCTAATATTTTCTCTTTAAAACTGTGTCAATTTTTGGAGAATGAATTTTTCAACCTTTTCATTGTGGAGGATTTTTCCCACAAG GTAGTAATGGGCAATGGATCAAAATCCTATCATAAATGATTGAATTTTCAATGTCATAGTGTGTGGAAATACTACTCCCTTTCCTCCATG TCTATCTTCTTAGATGTTCTGTCTTTGTCATCATCTGCTCCAGCACATACTTTGGACTCCTTTACAGGTGACCTTCCCCCCTCCCTCCTC AATAGGTGTCCTCAGTGTTTTCTAAGCATTTAAAACTGAATTTGACAAGTGGCTAAAAACTTAGTCTGAGACTTGTACTTAGTATATGGT TAATTATAGAAACAACAACTATTTTAAACAGTTACTCTGTTGACTGCTCTTTATGACTACACTTGTATGCCAGGAGGCAGCAGCCTATAC ACCATTAGACTCTTTACAAGCAACCAACGAACCAATTGCAGTGGTTGCAGTTGTCACAGTAGTCTTGCCTGGGCCAGACTGGGCTGGGCT GTGGGAAGCATTCCCCTTCAGGGGAGTTTCCACAGCTCAGCCCAGGCTCCAGTCTGGCTAGAGAGCATCCAGCCCATTCCTTGCCTCAGT GCCACCTTTTTCTGGGCAAGTAGCCAAGAAGTGACTTTATATGCAGTGAGTACTTCAGATAAACTTACAGCTACAGCTGCCGAAGAGTGG AGAAGGTTGACCACCATTTATTTAATTCTCTAGTGTAAAAACAATTGAGAGCAGTGTGCGTGAGCCCACAGACACCTGTGTTTCTGGGAG CTCTGGCAGTGGCGGATTCATAGGCACTTGGGCTGCACTTTGAATGACACACTTGGCTTTATTAGATTCACTAGTTTTTAAAAAATTGTT GTTCGTTTCTTTTCATTAAAGGTTTAATCAGACAGATCAGACAGCATAATTTTGTATTTAATGACAGAAACGTTGGTACATTTCTTCATG AATGAGCTTGCATTCTGAAGCAAGAGCCTACAAAAGGCACTTGTTATAAATGAAAGTTCTGGCTCTAGAGGCCAGTACTCTGGAGTTTCA GAGCAGCCAGTGATTGTTCCAGTCAGTGATGCCTAGTTATATAGAGGAGGAGTACACTGTGCACTCTTCTAGGTGTAAGGGTATGCAACT TTGGATCTTAAAATTCTGTACACATACACACTTTATATATATGTATGTATGTATGAAAACATGAAATTAGTTTGTCAAATATGTGTGTGT TTAGTATTTTAGCTTAGTGCAACTATTTCCACATTATTTATTAAATTGATCTAAGACACTTTCTTGTTGACACCTTGAATATTAATGTTC AAGGGTGCAATGTGTATTCCTTTAGATTGTTAAAGCTTAATTACTATGATTTGTAGTAAATTAACTTTTAAAATGTATTTGAGCCCTTCT GTAGTGTCGTAGGGCTCTTACAGGGTGGGAAAGATTTTAATTTTCCAGTTGCTAATTGAACAGTATGGCCTCATTATATATTTTGATTTA TAGGAGTTTGTGTCTGGGTCCCAGGAACATCTACTGGGGATGACTGTTAGGCAGCTTGTGATGATGTTTTTTAAAAAACCTAAGTAACTT GGGGAGACAGAGCATTTCAAACCCATATAGACACCTATCATACCTGTATATCCCCTAATACATGGAACATAAATTTCATTTCAGCTTTAT GCATTAATGTATTGAAGAGGCAGGCTTTTTTTCCAGTAATAATACTGTACATCTAAGGTTGCTATTCAGTAAAACTAATAGAAGAGATAA TTATTGAATACCTTGGAATATGTAGTGAGAAGAGGCCAAATTTTTCATGTTTGTGAGCATGTCTTTCAGATACTCGCTAATGGAGAAATT CACTTTAGACCTCTAGACCCCAAAACCAAGTTAGCAAGTGACAAAAAGTAAATTATTAATAGTCTGTAAAGTGGATGCTGGTCTTACAAA GCTCCTATTCACATGAACCCTATGGTTAATTAGAAAGAACTTGCTGTCTCCAGAAAAGGGAATGGAAATAATAACTATGTATCTTCTTTT CATGTAATTTGGTCACAGAATAAGGTATTCAAGTTAAGTCTAATCCAAGTCTTAGAGATCTTTAAGTATCCTAAAATAGCAGCCTAAGTA GTCATCATGTAAAGAAGTTGACTTTCAGGAATGTCAGCATTGACCTCTCCTTGCCACTGTTACTCAGCTAAACATAACTTGCCATTCTTA AAAATAAAAAAGCTCCCACCCAGAAACTCTAGTGATACTCAGTTTTGACCTCTTACTGCTTCCATGTGGGACTTCTTTTCAGCTTTTAAC CATTGGAATTTTCTACCTGCTATGTTCCTCTCTGGAAAATATCAATTTGGAAATGCTGCCTTTCAAATCAATGCCATGATCATCCATATT GTTGAGTTTGTTGTTGGTGTTCCAGAAGTGTCCCCATTTTACAACTTTATGCACACACCTGGCAAATCATTAACATGAGCATTCAACAGT ACTGGGATGGGTGGGGTGGGGGTAGGGGGCTCACCAACAGAACTGGCCAGTTGACATTGCCTGAAAAGGCACCACCTTTAAGGGCCAGTT GTGGGGTTGGTAAGCACAGTTATGAAAATTTCTATCTAGCCTCCGTTTTGAATGGTTTTAAGAAATTTTGTATATGGAGGATGGAAATGC TTATATATTTATTGAAAATCCTTTTATTTGAAATTAAAATTATTTGGTATATAATTGTTTGATATTTGGGGAGGGTTTTGGAGGGGAGAT AATGTCACTGATAAATTAAAAGCCTGTTGATTTTGCAGAAAGGTACTGTTAGTGACTGATAAGGATGCCTTTGTTTTGTACATGAACCAA ATCTTTGTTTTACATTTCTTTTATCCAAAATATTTAGGCATCTGACATTTTCAACCAGAATTTCAATTATATACTGTGATTTTTATTTGT TGCAATACATTACAATTTCAGAGGTACTTTGGGGCTCAAAAGCTAGGATTTCTAAGTCAGTATGTGCATTTCACACGATAAAGCTGTTAA TGGTGAGCAAAGTATTATATACTAACTAGATTTTTCCACATCTGTATAGTATATTATATGTATTTTGTGGTATTGAGAGTATAGAAAGTT TAGAGTGTCAAACATGCGTTTAATGTGTATTTTTAAACAAATTTATGGCAATTAAAATATTTGGAGACAAGGGTATCACATTTCAATTTG TAAAGATCTTTTTAACTCTACTGTGTCATTAAGATGCTTTGTACAATGCCAAACCATAGTTGGAGAAACTAAGTTTAATAAATATCAAAT >43140_43140_17_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000534358_AFF4_chr5_132240096_ENST00000265343_length(amino acids)=2219AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDL KLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQL DNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK KQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSD ESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNV PEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRT ISQSSSLKSSSNSNKETSGSSKNSSSTSKQKKTEGKTSSSSKEVKEKAPSSSSNCPPSAPTLDSSKPRRTKLVFDDRNYSADHYLQEAKK LKHNADALSDRFEKAVYYLDAVVSFIECGNALEKNAQESKSPFPMYSETVDLIKYTMKLKNYLAPDATAADKRLTVLCLRCESLLYLRLF KLKKENALKYSKTLTEHLKNSYNNSQAPSPGLGSKAVGMPSPVSPKLSPGNSGNYSSGASSASASGSSVTIPQKIHQMAASYVQVTSNFL -------------------------------------------------------------- >43140_43140_18_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000534358_AFF4_chr5_132240096_ENST00000378595_length(transcript)=6175nt_BP=4241nt CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGAAAAACCACCTCCGGTCAATAAGCAGGAGA ATGCAGGCACTTTGAACATCCTCAGCACTCTCTCCAATGGCAATAGTTCTAAGCAAAAAATTCCAGCAGATGGAGTCCACAGGATCAGAG TGGACTTTAAGGAGTCTCAGCAGTCCAATTTTGGCACTGGAGAACAAAAAAGATATAATCCTTCTAAAACTTCAAATGGGCACCAGTCTA AATCTATGTTAAAAGATGACTTAAAACTAAGCAGCAGTGAAGACAGTGATGGGGAACAGGATTGTGATAAGACAATGCCGAGGAGTACAC CAGGAAGTAACTCTGAACCTTCACACCATAATAGTGAAGGAGCAGATAACTCCAGGGATGATTCTAGTAGCCACAGTGGATCTGAAAGCA GCTCTGGATCTGACTCAGAGAGTGAAAGTAGTTCCAGTGACAGTGAGGCAAATGAGCCATCCCAGAGTGCATCTCCCGAGCCTGAACCCC CGCCAACAAACAAATGGCAACTTGATAATTGGCTGAATAAAGTGAACCCACATAAAGTGTCACCCGCCTCTTCAGTGGACAGTAACATCC CATCATCTCAAGGCTACAAAAAGGAAGGCCGAGAGCAGGGCACTGGGAATAGCTACACTGATACAAGTGGACCTAAAGAAACGAGTTCCG CTACTCCGGGACGAGACTCCAAAACCATCCAAAAGGGATCAGAAAGTGGGCGTGGGAGGCAGAAATCTCCTGCACAGAGTGACAGCACAA CACAGAGAAGAACTGTAGGCAAAAAACAACCCAAAAAGGCTGAGAAGGCAGCTGCTGAAGAGCCTCGTGGAGGCCTGAAGATAGAAAGTG AAACCCCTGTAGACTTGGCTAGCAGCATGCCCTCCAGCAGACACAAAGCAGCCACCAAAGGCTCAAGGAAACCCAATATAAAGAAGGAGT CTAAGTCTTCCCCTCGACCTACAGCAGAGAAAAAGAAATATAAGTCAACAAGTAAATCTTCCCAGAAATCAAGGGAAATCATAGAAACAG ATACCTCATCCTCAGATTCAGATGAAAGTGAGAGCCTTCCTCCTTCCTCACAAACTCCTAAGTACCCCGAGAGCAATAGGACTCCTGTTA AACCCTCCTCAGTGGAGGAAGAAGATAGCTTTTTTCGGCAACGAATGTTCTCTCCTATGGAAGAGAAGGAACTTCTTTCACCCCTCAGTG AGCCTGATGACAGGTACCCACTTATTGTGAAGATTGACCTGAATCTTTTGACTAGAATACCAGGAAAGCCTTACAAAGAAACAGAGCCGC CCAAGGGGGAAAAGAAAAATGTGCCAGAAAAGCACACGAGAGAGGCTCAGAAACAAGCCTCAGAAAAAGTTTCCAACAAAGGCAAGAGGA AGCATAAGAATGAAGATGATAACCGAGCCAGTGAGAGCAAGAAACCCAAAACGGAGGACAAGAATTCAGCAGGCCATAAGCCATCCAGCA ACAGAGAGTCATCTAAGCAGAGTGCTGCAAAAGAAAAGGATTTGTTGCCTTCTCCCGCTGGGCCTGTTCCTTCAAAAGATCCAAAAACAG AGCATGGCTCTCGGAAGAGGACTATTAGTCAGTCTTCTTCCTTAAAGTCAAGCAGTAACAGCAACAAGGAGACGAGTGGCAGCAGCAAAA ACAGTTCCTCCACATCAAAGCAGAAGAAGACCGAAGGGAAGACTTCCAGTAGCTCCAAGGAGGTTAAGGTAAAGTGTTGGGGGCCTGGGG CTTTTGAAAATCATTCAACTTGCCATGTGACTTTTCCAGGGTGACACTGTGCTTTGAAATTATTGTAACATCTCAGTAAATATATAGGCC TATGTCTTTTACCCTCTATATGTAATAATCCTGATAAATGAATACAGTGATATAAGACTGTGAAGGTGGTAAGTCAGCTGGTCACATACA TATTGAAAGAAAAACCCTTGGGTACAGTGGCTCATACCTGTAGTCCCAGCTATTTGGGAGGCTAAGATGGAAGGATCATTTGAGGAATTT >43140_43140_18_KMT2A-AFF4_KMT2A_chr11_118355029_ENST00000534358_AFF4_chr5_132240096_ENST00000378595_length(amino acids)=1956AA_BP=57 MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR PSIPVKQKPKEKEKPPPVNKQENAGTLNILSTLSNGNSSKQKIPADGVHRIRVDFKESQQSNFGTGEQKRYNPSKTSNGHQSKSMLKDDL KLSSSEDSDGEQDCDKTMPRSTPGSNSEPSHHNSEGADNSRDDSSSHSGSESSSGSDSESESSSSDSEANEPSQSASPEPEPPPTNKWQL DNWLNKVNPHKVSPASSVDSNIPSSQGYKKEGREQGTGNSYTDTSGPKETSSATPGRDSKTIQKGSESGRGRQKSPAQSDSTTQRRTVGK KQPKKAEKAAAEEPRGGLKIESETPVDLASSMPSSRHKAATKGSRKPNIKKESKSSPRPTAEKKKYKSTSKSSQKSREIIETDTSSSDSD ESESLPPSSQTPKYPESNRTPVKPSSVEEEDSFFRQRMFSPMEEKELLSPLSEPDDRYPLIVKIDLNLLTRIPGKPYKETEPPKGEKKNV PEKHTREAQKQASEKVSNKGKRKHKNEDDNRASESKKPKTEDKNSAGHKPSSNRESSKQSAAKEKDLLPSPAGPVPSKDPKTEHGSRKRT -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for KMT2A-AFF4 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for KMT2A-AFF4 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for KMT2A-AFF4 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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