FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:KMT2A-CBL (FusionGDB2 ID:43149)

Fusion Gene Summary for KMT2A-CBL

check button Fusion gene summary
Fusion gene informationFusion gene name: KMT2A-CBL
Fusion gene ID: 43149
HgeneTgene
Gene symbol

KMT2A

CBL

Gene ID

4297

867

Gene namelysine methyltransferase 2ACbl proto-oncogene
SynonymsALL-1|CXXC7|HRX|HTRX1|MLL|MLL1|MLL1A|TRX1|WDSTSC-CBL|CBL2|FRA11B|NSLL|RNF55
Cytomap

11q23.3

11q23.3

Type of geneprotein-codingprotein-coding
Descriptionhistone-lysine N-methyltransferase 2ACXXC-type zinc finger protein 7lysine (K)-specific methyltransferase 2Alysine N-methyltransferase 2Amixed lineage leukemia 1myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)trithorax-likeE3 ubiquitin-protein ligase CBLCas-Br-M (murine) ecotropic retroviral transforming sequenceCbl proto-oncogene, E3 ubiquitin protein ligaseRING finger protein 55RING-type E3 ubiquitin transferase CBLcasitas B-lineage lymphoma proto-oncogenefragile si
Modification date2020031920200327
UniProtAcc

Q03164

Q8IUK8

Ensembl transtripts involved in fusion geneENST00000354520, ENST00000389506, 
ENST00000534358, ENST00000420751, 
ENST00000264033, 
Fusion gene scores* DoF score79 X 196 X 13=20129211 X 14 X 7=1078
# samples 24112
** MAII scorelog2(241/201292*10)=-6.38411287931608
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/1078*10)=-3.16725086714399
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KMT2A [Title/Abstract] AND CBL [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKMT2A(118353213)-CBL(119155677), # samples:1
Anticipated loss of major functional domain due to fusion event.KMT2A-CBL seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF.
KMT2A-CBL seems lost the major protein functional domain in Hgene partner, which is a epigenetic factor due to the frame-shifted ORF.
KMT2A-CBL seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
KMT2A-CBL seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
KMT2A-CBL seems lost the major protein functional domain in Hgene partner, which is a transcription factor due to the frame-shifted ORF.
KMT2A-CBL seems lost the major protein functional domain in Tgene partner, which is a CGC due to the frame-shifted ORF.
KMT2A-CBL seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKMT2A

GO:0044648

histone H3-K4 dimethylation

25561738

HgeneKMT2A

GO:0045944

positive regulation of transcription by RNA polymerase II

20861184

HgeneKMT2A

GO:0051568

histone H3-K4 methylation

19556245

HgeneKMT2A

GO:0065003

protein-containing complex assembly

15199122

HgeneKMT2A

GO:0080182

histone H3-K4 trimethylation

20861184

HgeneKMT2A

GO:0097692

histone H3-K4 monomethylation

25561738|26324722


check buttonFusion gene breakpoints across KMT2A (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CBL (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerKB3..KMT2Achr11

118350953

+CBLchr11

119148875

+
ChimerKB3..KMT2Achr11

118353210

+CBLchr11

119155678

+
ChimerKB3..KMT2Achr11

118353210

CBLchr11

119155678

+
ChiTaRS5.0N/AAY125965KMT2Achr11

118353213

+CBLchr11

119155677

+


Top

Fusion Gene ORF analysis for KMT2A-CBL

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
Frame-shiftENST00000354520ENST00000264033KMT2Achr11

118350953

+CBLchr11

119148875

+
Frame-shiftENST00000389506ENST00000264033KMT2Achr11

118350953

+CBLchr11

119148875

+
Frame-shiftENST00000534358ENST00000264033KMT2Achr11

118350953

+CBLchr11

119148875

+
In-frameENST00000354520ENST00000264033KMT2Achr11

118353210

+CBLchr11

119155678

+
In-frameENST00000354520ENST00000264033KMT2Achr11

118353213

+CBLchr11

119155677

+
In-frameENST00000389506ENST00000264033KMT2Achr11

118353210

+CBLchr11

119155678

+
In-frameENST00000389506ENST00000264033KMT2Achr11

118353213

+CBLchr11

119155677

+
In-frameENST00000534358ENST00000264033KMT2Achr11

118353210

+CBLchr11

119155678

+
In-frameENST00000534358ENST00000264033KMT2Achr11

118353213

+CBLchr11

119155677

+
intron-3CDSENST00000420751ENST00000264033KMT2Achr11

118350953

+CBLchr11

119148875

+
intron-3CDSENST00000420751ENST00000264033KMT2Achr11

118353210

+CBLchr11

119155678

+
intron-3CDSENST00000420751ENST00000264033KMT2Achr11

118353213

+CBLchr11

119155677

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000534358KMT2Achr11118353210+ENST00000264033CBLchr11119155678+1376741092353981791
ENST00000389506KMT2Achr11118353210+ENST00000264033CBLchr11119155678+137444086053751791
ENST00000354520KMT2Achr11118353210+ENST00000264033CBLchr11119155678+137444086053751791
ENST00000534358KMT2Achr11118353213+ENST00000264033CBLchr11119155677+1376741092353981791
ENST00000389506KMT2Achr11118353213+ENST00000264033CBLchr11119155677+137444086053751791
ENST00000354520KMT2Achr11118353213+ENST00000264033CBLchr11119155677+137444086053751791

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000534358ENST00000264033KMT2Achr11118353213+CBLchr11119155677+0.0002936240.9997063
ENST00000389506ENST00000264033KMT2Achr11118353213+CBLchr11119155677+0.000285490.99971443
ENST00000354520ENST00000264033KMT2Achr11118353213+CBLchr11119155677+0.000285490.99971443

Top

Fusion Genomic Features for KMT2A-CBL


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KMT2Achr11118353210+CBLchr11119155678+0.000597810.99940217
KMT2Achr11118353210+CBLchr11119155678+0.000597810.99940217

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for KMT2A-CBL


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr11:118353213/chr11:119155677)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KMT2A

Q03164

CBL

Q8IUK8

FUNCTION: Histone methyltransferase that plays an essential role in early development and hematopoiesis (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac) (PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:24235145, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Catalyzes methyl group transfer from S-adenosyl-L-methionine to the epsilon-amino group of 'Lys-4' of histone H3 (H3K4) via a non-processive mechanism. Part of chromatin remodeling machinery predominantly forms H3K4me1 and H3K4me2 methylation marks at active chromatin sites where transcription and DNA repair take place (PubMed:25561738, PubMed:15960975, PubMed:12453419, PubMed:15960975, PubMed:19556245, PubMed:19187761, PubMed:20677832, PubMed:21220120, PubMed:26886794). Has weak methyltransferase activity by itself, and requires other component of the MLL1/MLL complex to obtain full methyltransferase activity (PubMed:19187761, PubMed:26886794). Has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', while it has higher activity toward H3 acetylated on 'Lys-9' (PubMed:19187761). Binds to unmethylated CpG elements in the promoter of target genes and helps maintain them in the nonmethylated state (PubMed:20010842). Required for transcriptional activation of HOXA9 (PubMed:12453419, PubMed:20677832, PubMed:20010842). Promotes PPP1R15A-induced apoptosis (PubMed:10490642). Plays a critical role in the control of circadian gene expression and is essential for the transcriptional activation mediated by the CLOCK-ARNTL/BMAL1 heterodimer (By similarity). Establishes a permissive chromatin state for circadian transcription by mediating a rhythmic methylation of 'Lys-4' of histone H3 (H3K4me) and this histone modification directs the circadian acetylation at H3K9 and H3K14 allowing the recruitment of CLOCK-ARNTL/BMAL1 to chromatin (By similarity). Also has auto-methylation activity on Cys-3882 in absence of histone H3 substrate (PubMed:24235145). {ECO:0000250|UniProtKB:P55200, ECO:0000269|PubMed:10490642, ECO:0000269|PubMed:12453419, ECO:0000269|PubMed:15960975, ECO:0000269|PubMed:19187761, ECO:0000269|PubMed:19556245, ECO:0000269|PubMed:20010842, ECO:0000269|PubMed:21220120, ECO:0000269|PubMed:24235145, ECO:0000269|PubMed:26886794, ECO:0000305|PubMed:20677832}.FUNCTION: Acts as a synaptic organizer in specific subsets of neurons in the brain (By similarity). Essential for long-term maintenance but not establishment of excitatory synapses (By similarity). {ECO:0000250|UniProtKB:Q8BGU2}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+835137_14313623932.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+83517_10213623932.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+835561_56413623932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+835568_57113623932.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+836137_14313623970.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+83617_10213623970.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+836561_56413623970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+836568_57113623970.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+836137_14313623973.0Compositional biasNote=Poly-Gly
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+83617_10213623973.0Compositional biasNote=Ala/Gly/Ser-rich
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+836561_56413623973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+836568_57113623973.0Compositional biasNote=Poly-Pro
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+835169_18013623932.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+835217_22713623932.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+835301_30913623932.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+836169_18013623970.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+836217_22713623970.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+836301_30913623970.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+836169_18013623973.0DNA bindingNote=A.T hook 1
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+836217_22713623973.0DNA bindingNote=A.T hook 2
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+836301_30913623973.0DNA bindingNote=A.T hook 3
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+835123_13413623932.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+835147_15213623932.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8356_2513623932.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+836123_13413623970.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+836147_15213623970.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8366_2513623970.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+836123_13413623973.0MotifIntegrase domain-binding motif 1 (IBM1)
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+836147_15213623973.0MotifIntegrase domain-binding motif 2 (IBM2)
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8366_2513623973.0MotifMenin-binding motif (MBM)
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8351147_119513623932.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8361147_119513623970.0Zinc fingerCXXC-type
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8361147_119513623973.0Zinc fingerCXXC-type
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816477_688477907.0Compositional biasNote=Pro-rich
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816689_834477907.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816856_895477907.0DomainUBA

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8351703_174813623932.0DomainBromo%3B divergent
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8352018_207413623932.0DomainFYR N-terminal
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8353666_374713623932.0DomainFYR C-terminal
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8353829_394513623932.0DomainSET
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8353953_396913623932.0DomainPost-SET
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8361703_174813623970.0DomainBromo%3B divergent
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8362018_207413623970.0DomainFYR N-terminal
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8363666_374713623970.0DomainFYR C-terminal
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8363829_394513623970.0DomainSET
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8363953_396913623970.0DomainPost-SET
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8361703_174813623973.0DomainBromo%3B divergent
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8362018_207413623973.0DomainFYR N-terminal
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8363666_374713623973.0DomainFYR C-terminal
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8363829_394513623973.0DomainSET
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8363953_396913623973.0DomainPost-SET
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8353906_390713623932.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8363906_390713623970.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8363906_390713623973.0RegionS-adenosyl-L-methionine binding
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8351431_148213623932.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8351479_153313623932.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8351566_162713623932.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8351870_191013623932.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8351931_197813623932.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8361431_148213623970.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8361479_153313623970.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8361566_162713623970.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8361870_191013623970.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8361931_197813623970.0Zinc fingerPHD-type 4
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8361431_148213623973.0Zinc fingerPHD-type 1
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8361479_153313623973.0Zinc fingerPHD-type 2
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8361566_162713623973.0Zinc fingerPHD-type 3
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8361870_191013623973.0Zinc fingerC2HC pre-PHD-type
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8361931_197813623973.0Zinc fingerPHD-type 4
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816227_240477907.0Calcium binding.
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816357_476477907.0Compositional biasNote=Asp/Glu-rich (acidic)
TgeneCBLchr11:118353213chr11:119155677ENST0000026403381647_351477907.0DomainCbl-PTB
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816176_248477907.0RegionNote=EF-hand-like
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816249_351477907.0RegionNote=SH2-like
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816352_380477907.0RegionNote=Linker
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816358_906477907.0RegionRequired for ubiquitination of SPRED2
TgeneCBLchr11:118353213chr11:119155677ENST0000026403381647_175477907.0RegionNote=4H
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816381_420477907.0Zinc fingerRING-type


Top

Fusion Gene Sequence for KMT2A-CBL


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>43149_43149_1_KMT2A-CBL_KMT2A_chr11_118353210_ENST00000354520_CBL_chr11_119155678_ENST00000264033_length(transcript)=13744nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGTGGAACGGCCGCCTTCTCCATTCTCCATGGCCCCACAAGCTTCCCTTCCCCCG
GTGCCACCACGACTTGACCTTCTGCCGCAGCGAGTATGTGTTCCCTCAAGTGCTTCTGCTCTTGGAACTGCTTCTAAGGCTGCTTCTGGC
TCCCTTCATAAAGACAAACCATTGCCAGTACCTCCCACACTTCGAGATCTTCCACCACCACCGCCTCCAGACCGGCCATATTCTGTTGGA
GCAGAATCCCGACCTCAAAGACGCCCCTTGCCTTGTACACCAGGCGACTGTCCCTCCAGAGACAAACTGCCCCCTGTCCCCTCTAGCCGC
CTTGGAGACTCATGGCTGCCCCGGCCAATCCCCAAAGTACCAGTATCTGCCCCAAGTTCCAGTGATCCCTGGACAGGAAGAGAATTAACC
AACCGGCACTCACTTCCATTTTCATTGCCCTCACAAATGGAGCCCAGACCAGATGTGCCTAGGCTCGGAAGCACGTTCAGTCTGGATACC
TCCATGAGTATGAATAGCAGCCCATTAGTAGGTCCAGAGTGTGACCACCCCAAAATCAAACCTTCCTCATCTGCCAATGCCATTTATTCT
CTGGCTGCCAGACCTCTTCCTGTGCCAAAACTGCCACCTGGGGAGCAATGTGAGGGTGAAGAGGACACAGAGTACATGACTCCCTCTTCC
AGGCCTCTACGGCCTTTGGATACATCCCAGAGTTCACGAGCATGTGATTGCGACCAGCAGATTGATAGCTGTACGTATGAAGCAATGTAT
AATATTCAGTCCCAGGCGCCATCTATCACCGAGAGCAGCACCTTTGGTGAAGGGAATTTGGCCGCAGCCCATGCCAACACTGGTCCCGAG
GAGTCAGAAAATGAGGATGATGGGTATGATGTCCCAAAGCCACCTGTGCCGGCCGTGCTGGCCCGCCGAACTCTCTCAGATATCTCTAAT
GCCAGCTCCTCCTTTGGCTGGTTGTCTCTGGATGGTGATCCTACAACAAATGTCACTGAAGGTTCCCAAGTTCCCGAGAGGCCTCCAAAA
CCATTCCCGCGGAGAATCAACTCTGAACGGAAAGCTGGCAGCTGTCAGCAAGGTAGTGGTCCTGCCGCCTCTGCTGCCACCGCCTCACCT
CAGCTCTCCAGTGAGATCGAGAACCTCATGAGTCAGGGGTACTCCTACCAGGACATCCAGAAAGCTTTGGTCATTGCCCAGAACAACATC
GAGATGGCCAAAAACATCCTCCGGGAATTTGTTTCCATTTCTTCTCCTGCCCATGTAGCTACCTAGCACACCATCTCCCTGCTGCAGGTT
TAGAGGACCAGTGAGTTGGGAGTTATTACTCAAGTGGCACCTAGAAGGGCAGGAGTTCCTTTGGTGACTTCACAGTGAAGTCTTGCCCTC
TCTGTGGGATATCACATCAGTGGTTCCAAGATTTCAAAGTGGTGAAATGAAAATGGAGCAGCTAGTATGTTTTATTATTTTATGGGTCTT
GAGTGCATTTGAAGGTGTCCTTCAGTTCCCACGTAGAGAGAGTGTGGATTATATTACATGATAACCTACCTGGGGAACAGTCCAGAAAGC
TATAGAACAAGTATTTTGCTGGAAATCCTAATTGAGGACTTAAGACTTCCTGGGTTAAGGATGTGGCCGTGTGTGTGTGTGTCTGCCTGT
GGTTGTATGTGTCCTTGTGATTATAAGATTAACCTGCTGTGTGTGTTAATTCCAGGCAGGGAATTAGCACAAAAGGTTTAGGAAGGAATC
TTTTTTTAAAGACTTCCATCTACTGTGGTATTATACCCAAGCCTAGTGTGTATTACAACTTCAACACTCCCCTTTGGCTTATATTACCAT
GTGCATAGCTAAAGTCTTCTATTTTTAGAACACCTTCTGTCTGTTCTTTCCCCATCAACTCCTTCCTCATCCTTCTTGGTGTTCTGTCAT
GGGCCATGGGCTTGCTATGGCCAGCCTTACTGAGGCCAAGCAGCTTATGGGATGTTCTTTATTGTGTGTGATGGTATTGGTTTGTTTGGT
AGATAAGTGGGAGGAAAAGTACTGTTGCTACACTATTATAGGCATGTTTGATACTAGCAGCTAACACTGGTCACTCCAAAGCACTGTTTC
TATAGGAACATTGAAGCTATTAAGATGTTTTGATTATCCTAATTACATAATGACCGATTTGAGATAGAGGCCTTTAAATACATTCCATGC
CCTCCCCAGAAAATAGTCTGTGGGAGTCAGTTGCCTTGGTGCCAGGTATGTGTTCTGATGTAGGTCATGAGTCTTTCTACTTAATGGGAA
GGGAAGAACATTTGTTTCCAGGATGACTTTCTGGCCAGAATACCGGAAAGCTTTTAGGAAGCTTCGTTCACATGCTATTTAAATGCACAA
AATAGACAGTAAGGATTTATCTGTTCAGTTTTTCTTCCCAGTGAATTAATTTCAGCTTATATGGGTGTCTTCATTTGAACATGAGGAATA
TTAGGTTATATTTTCAGCAGTGGTTTTTTCCTTTGCCCTTTAAGGAGTGGGGATAATGTCCACGGTGGCCCAGCCTCTTGCTGATGGCAC
CTTCCCTGCATTGCTGCCTCCCGATGATGTGGTTCTTTTCTTGTGCCTGTGGCTTTGGGAATGTAACATCTCTTTCCTCCTTTCCTTCCC
TTTTCCTCTTCACCTGAGGTCCTAAATACTCTCTGTAATTACTGTGTTCTTCACGGTAATTAGACATCATTCAGTGAATAAATTACTGTA
GTCAAAGACAGTATGGGCTGGCAGTTTGTGTAATTGCAAGTTCATAAAGAGAATTGAGGGTCCAGTTGGGAGAACTATTAGTCAGTTCTT
TTATATGCTGATAAATGATCCCTCGAGTTCAGTTAGTATTCTGTCCAGAGTGTTTAGCTCACTTTCTTAGCAGTGTGTAAGCTTTCTCCA
TGTCAGAAGCAAGCCTGCTCTTTGATAAATCTGTCTTCCTGAAAATCTAAATCATGCTTTTGTCTTTAGATCTACACAGAAATGACCCTC
CTTGGATCAGTTTTCTTTCCAGTCTAATCATCTTTGGAACTAAAACTTGTTCTAACTCGTCTCTTGGCATTCAGCTACTCCTAGATCTTT
TGGTTTTATCCCCTGGCCTCAGAGCCATTTATATTCCCAGAGTAGGCAGTACAGGATCTCGTGTTGATTTGCTGTGGTTACCCAGTGTCT
TCTCTACATGGCATAAAGCGGCAAAGCCCACCATTAGGTGAGGCGGTCCCGAGTTGAGGTAGAGTGGGGCAGAGGAAGATGGCAGTGAAT
ATCAAACAGTAGACCGCCATCAACTTCTAACAGCCAGTACACACACTGTTTCATTTTGAGGTAACGTTCAGTTTTGCATTTTGTTTAAAT
ATTGAAGGCCTAGACAAAGAACTAGAAAAAAAAAAGCAGTTTCCAGGCCCATCCATATTGTAATTTTTCTTTATCTGCAGATATTGCCTG
TAGTCTAAAGATCTCTTTGGAAGACAAAGCATTGGCTATATATCTTTTGCCTTTTCCATGCATCTAAATCTTCTCTGGAGATTATCTCCC
TACTGTGTAGGTTAAGGGCAGTCTCGACTTTTCCTTTTTTGAGTCCTGTGTGGCTCTTTGAATCAGCGTGAAACTGAGGCTCCAGCTCCC
TGTGTTGTGTGTGTGTGCCATCCATGGGCTTGGGTGTCAGTTTGTCACAGGTATCTGCCAGCATTCAAGGTTTTGGATCATTTCATGAGG
ATCTTTCCTTTGACTGGGTGCTGTGAGGACACACCTGGGTCTGTGCCTGAGATTGCCAGGCAAGATTAAGGAAAGTTTTCATGTGGCTTT
TGTTTTGAGGTTATTCTCAAAACCTTAATTTCTTATATTTTCTGTTGACTAAGGCACCAGTAACCCATTCTTCACCCTCCATTTGTATGG
CAATTTAAAAGTCTTTGGCTTTGCTCTGAATTTAATTAAAACTGCCTTTTATGAACAGACTTCGAGTTTTGCCATTTTGGGCAAGCCCTT
CCGCTTGTCCCTTCCTAGTGGCTAATAAAGTAAAAAAACCCACACTACTTTGTTCTCTTTTTCTCATATTCATTGGGCTGTTGTATTCAG
CCAGTCTCATGCTTTCCCTGGGTCTTCACGGATTGCTTTCCAAGCTGCCTTGTTGCGGGGTTGCTGCAGAGCAGCAACTGGACCTTTCCA
GCTGTCGCCATGTTCCTTCCACTAAAGTAGAGGGTTCTTAAAATGGAAAAACCTGTGGGCTCTTCATATACCTCCCTTTAGTTAAGTAAT
AGACCAGGCAGCTTCTCATCTCAGCATTTACCTGTTAATATTTTTGTGAATAGTGCTCTCTACCTGTGGGTGGCCGTTCTCTTCCACTTG
CTCGTCTCCCCCCAGCCCCATTCTGCATAATCTACCATTCTTCTCCTCTCTTTCTCTTCTTATACAGACCCTCATTACTGGGGCCCAAGA
TGTGGGATACTACTGTTAGTATTATTTAACTATTTTGTAGATTTAAAAGATTTCTGGTTAAGGGAGGTGGGGGTCACTGTTCATCACTCT
TAAAATATGTGTTTTCTCTATAGAAAAGTAAAATGTGTTTATGGTCCCAAACAGTCAACTCACAAATTTTTATAACAAAATTTCCTTGTA
AAAACTAGGGACCATCTATATATTCCCTTTAAGATCTAGTTCTTTTTGTAGGTGTTCAGCAATGGTGATAAAGCAGAATATTCTCCTACC
TCACGTCATTAAAGTCAGAAGATTATAGACCTTCTCAAACTATAAGTCCCTCTTCTTGCCGTTGGCCTTTCTGACTCTGGAATGACCACT
GTTCATTGAAAAATAGTTTTCTGACTATTGGTCTGGCTCTAACAGTTTGTTTGTTCATCCAGCAAATGTTTATGAGTGATGACCATGTGC
CAGAAATGTCAGGTATGTGTCCTTCCCTTGGCGCCACATAGTAGTTTACTAATGTTTGGGGGATTGTACTTGGACTGTCATAGCCTCTGC
GTTTGACCTTAAAATAGCTCTTCCCAGTAAGATTGTGCAATTTTTATTCACAGCTCTTCCATGTAGACTTACCTTTCCTCATAGAGCTAT
CCTGGTTAATAACAGGCCAAGATTCTCCCATTATCCCCTGTTGTCTCCTGTAGCTTTGATAATGCCTGGGAGATTCCTTGGTGTAAGTGT
CATGGATACCGACTGTTTTTATGTTGGAATTTGTTCCAACATAATTAGAATCTGTTTGGTGAGTTGAAAGGTAAGTTGGCTCAGAGTTGC
ACAGTAGGGCATTAAATGTTTAAGCAAAGCATCTGCCCACACTCCCCTTTCCAATCTAGTGCCTTCCTTGAACTTTTTCCTGAGCTGCTA
CGTCCCTAATCCCCCTTGTTGGGAGGATTTTCGTATCACCCTTATGGGACCTGTCACCATGTCCTGTACTATTTGGAATTGGTTTTCCAG
TCTTTCAACAACCGTTGTGGCTAACTATGTTTTAGAAGGGCTGGAGGTGTGGGCCCTGTCTTCGGGTCTCAGGACCCAAAGATCCTTTAG
TCAGTTGTTGGGTCTTCCAAGAGCCAGACATTAATACAGATTGAACTCCATCAGTCCCCTAATTGTCAGCCTTTACCTCCCTCCCAGAGC
AAGGAGTTTAGGGATTCTAAAGCTTAGTGTCCACACATCATTCTACCAGACCTTAGAGCTTTAGAAGCTCAATCTAAAATACTGTAACTC
AGCATAAACTATTACTATCACTCCTTTGAACTCAGTCTCCATGAGCAGTGTTTTGTTGGAAATACATAGAACGGCTTAATGCCTAGAGGG
TGGTGGATAGTGAAGGACGGTCAAGGTTATATTTTTGACTGCTTAGGGATTCTTTGGATCCAAGAAACAGAAATGTTCAAGCGGAATAAA
GGAGGGAGTGGAGTTGTGGTAAGGATGCAGGGTATTTCGCAGAACCCAGGACGGGAAGTGCCTTTGGTTCTTGGGTGGAGCTGGAACTGC
AGAGCTTTGCACCTAGTCCTTTCTCCCGCTTCACAGTCTGCTTATGGTATATGTGGCCCCCAAATAGGCACTCTAGTCCTCAAGTCTACA
CCACCTTCCAACTCTGGGGATCACCATGAACAAATTCTCAATTTCCCATACTTAATTTTTTTTTTTTTTGAGATGGAGTCTCGCTGTGTC
GCCCAGGCTGGAGTGCAGTGGTGCAGTCTCAACTCACCACAACCTCTGCCTCCCAGGTTCAAGCAGTTCTCTGCCTCAACCTCCCGAGTA
GCTGGGATTACAGGCGCCTGCCACCATGCCCAGCTAATGTTCATATTTTTAGTAGAGACAGGGTTTCACCGTCTTGGCTAGGCTGGTCTT
GAACTCCTGACCCTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTAAGATTACAGGCGTGAGCCACCGCGCCCGGCCCATACTTCGTA
TTCTTAAAAAAAACTACACTCAGCCCAGCACATTGATCAAGTATCTATCTCTGAGCAGTTGGCCTTGCCAGGGAGAGCAGAGATGTGGCA
GGCTCCTTCAGCTGGAGACAGGGAGCTTCTCAGAGAAGTGAGCAGAGACTCCACAGACACCCTAAAAAGGCTTCTACTCAAGAAGTAAAG
CCACTACTCCTGCCTTTTTGCTTAGTGGACAGGAAGGCACAGGAGTTTGTCTGGGACATCATAGAAATTCTTAGGTTTAACTTAATTCTG
GTCATTGTCTTCTTTATTTCCTGTTTTTCTTCCCTTTGTCAGTCTTCGCATCCAAGATTTCTTCCCTCCCTCTTGTGGGCCAGCCTGTCC
TGTTCCAGAGCTAGCCTGTTCCTGGGTAGCCTTCCTTAGCCTCCATTCAGCCTCAGGTCTTTTGCCTTCTTCCGTGTTTATTTAGAGAGC
AGAATCTAATAACGGGTTCCACTGTAGCCACTATCCATGGACTTCTGGGTCCTCTTCAGGTTTGAGTGCTTGAAAATGTTCATTCTCTGG
GCTTGTGGCCTGTCTCCTCCACTCTCCTCCTCACCCTCTCGCTCCTTCCTGTGTGAGGGCCGCTCTGCAGTAATGTTCTCAGGCAAGCCT
TCCTAGGCACCTCAGAAACTACTTTGCCAGAGCCAGTAAGAATATATAATATTGGAGCAGTTGCCAGGATAGAAATTAAATATAGATTCC
AGTTTAGGATAGAGTTTTTACCGAGAGCTCTTTAGACAGTATACCTGTGTCTTCTCTGGCAATTGCTTTCATTTTAGTCCTATATAAAAG
CTTTCCTTTTCTGTTTTTTTTTAAAACTATGCTTTTGCTTGCCTAAATCTTTTGATCTTATATTTCTCTCATCTCAGAGCCTGTCCTGAG
TTGTAAGGTATTTCATACTGCCTTACTTAAAAGTTTTTTAAACTACTAGAGTCATTTGATACACACAGAAGTTACCTAATAATCCAAAGA
TGTCCATCAAGGGAGGAAGGGTGGGTCATCAGACTTTGCCTTTGATGTTGTAGACTAGGCTCCTGAGTTAAGCAGCAGAGGGACAGCAGT
GCCATGTGCCTTCACTGTGTCCCAGGAAATCTGGGTTGGTTCCAGTGGGAAATACCAGTATTTCTTGGTTCTGGAAAGTAGCAAAAGAGT
AGGAGATGGGGAAATAGGGATGGGGAGAGCAAGCCCCGCATGTCCATGGCGAGTCAGGTGGGGAGCACGGGTGGAAGGGCCGGCTGTTGA
CAGACAGACTAAGCTGTGTGGTGCTCTTGCCGCCCCTTCCTGGGTACAGAGCTTGAGAAAAATGCAGCCGACCACTCCCTGTGTTTGTAC
AGAGCAAAGCCCAAAAGCCAACCTCAGATCTCCTGATTTGGCAGCTGAAGAAATCAGCAGAGTCCTGATTGCCTGATTCAGTCCCAAAAA
TGAATGTCAGGCCCCGCCCCCTCCCCACCAACATTGCCTCTCCTACATTCTCCTTCTGCCCCTAAATCAGACAGGAGGCCAGAGAGGAGT
ATTGCTCAATGCGTGCTATGTGCAACTCCTCAGGCCTTGTGCCACCTCCATGCTGAGCCCTGAAGCAGGGTGTCCTGGGTGCCTGTGTGT
CAGCTCCCTCCTCTCTACCTACCTCTGACCTTCTTGTGGGTGAGGGTGGCCATGCTTATGGCCATCTTAAAACTGGAGAGGCAGAGAACT
ACTTATGAGTCTGTAGACCACGTGTTGTCTTCCATGGCCTGTTTCTCCTGCTGTCTGGGTGAGTGAGCCTGCAACGCAATGCCCATGAGA
GTAAATGCCTCCTGACCTACCCTGCTCAGCACTGTTCTAGTGTCTTGGCCTTGAAAGAAAAGCCTGACTTCCTGCTGACACATGTGGTAG
GGGCATGGCAGCTATGAGGCACCTCCTACGTCTGTTTTCTGGCTGTGGTGACTTGGGATTTTTAACCTTATATATCTTTTTCCTTTACTC
AAAACAAAACAATTTTTAGCACACTGAAAAAAAAAAAAAGCCAAATGTTTTGTGCCTTTCTAAGGCAGCACTGTATCCCAGGCTGCATTT
TAGGACTTAATATGGAAATACCAGAGTCTGAGCTCCTCTACCTTGAGTTTCATTAGTCCTTAGTGTCTAGGAGACAGGAAAGAATGCTCT
CTGTGACTGGAGAGGTGACATGCAGGTGCAGTGTGTCTGGAGTCCCTTTCCCCTGCTGTGAGACTTCAGTGGAGGAGAGAAGCATTGTAC
CCTGGGATCATTTGGTTGGTTCCAATCACAAGCTTAGTTATCAGGTTGCATGCCTTGTCTCCTGCAAAAGACAGAATGTTTCACAATTCC
CAGGTAAACTCTGGACCATTCCAAGTGTCCTAGCCTTCTGATGACATTAATTACCTAGTTGTGTCGAGGAGTATAGGATGGACTCTCCTG
AGAAGGGGAGGTTGGTGGCTTTGTCTTTTCTTTTTGCTGGATCCTGAACTGGTCTAGACCTCCTGCCCCCACCCCCCAGCCCCCATCAGA
TGTGGCTGGCCTTTCATTTGAAGGCTTCAGACTTAAAGCATTAAGCAGCTAGTGCCCTCTGCAGGGCCTGGTTTCCCCAGGGAAGGGCAG
CAAGGAACATGGGACCAGAAGCCTGTCCTCAGTAATGTGACTATAGTGAGCTTTAGCAAAAGTTTTTCTATATAATGACATCTTACTTAT
CTTTTACCCTTTCCTCAGTTTTCCCCTGCCTTTAACTAATAAAGAATTGGGAGACAGAAATTTTAAAGTCCTCCTTATTCAAGATTTTGA
AATTCTTAGCCTGGGAGTGCTGGAGAGAACCTGATGCTTTCTCCAGAATGAAGAGTCCCAATTTGTATATCAGTGTTAAGAAGAAAACAA
AACAAACACATAGGTGAGATTTTCGTGGACTATTTTAAAAATGTGTCATTAATATAAAAAATTTATATTAGCAGTATTTAATCATTCTCA
CCTGTAAAGAATAAGAAAAACAGAAGGTAAATATTCTTACAGAGAATAGCAGAGCTTTAAGATTCATTTTCATTTTAAGTCCATTTTATT
TTGCCAGTGTATTAATGTTTAGAAGTCTGTTTTACTAATGTTATTTATTAATTTTTTTTCATTTCCATACACAGTTAGTTAACTAAAGAG

>43149_43149_1_KMT2A-CBL_KMT2A_chr11_118353210_ENST00000354520_CBL_chr11_119155678_ENST00000264033_length(amino acids)=1791AA_BP=7
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVG
AESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDT
SMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMY
NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPK

--------------------------------------------------------------
>43149_43149_2_KMT2A-CBL_KMT2A_chr11_118353210_ENST00000389506_CBL_chr11_119155678_ENST00000264033_length(transcript)=13744nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGTGGAACGGCCGCCTTCTCCATTCTCCATGGCCCCACAAGCTTCCCTTCCCCCG
GTGCCACCACGACTTGACCTTCTGCCGCAGCGAGTATGTGTTCCCTCAAGTGCTTCTGCTCTTGGAACTGCTTCTAAGGCTGCTTCTGGC
TCCCTTCATAAAGACAAACCATTGCCAGTACCTCCCACACTTCGAGATCTTCCACCACCACCGCCTCCAGACCGGCCATATTCTGTTGGA
GCAGAATCCCGACCTCAAAGACGCCCCTTGCCTTGTACACCAGGCGACTGTCCCTCCAGAGACAAACTGCCCCCTGTCCCCTCTAGCCGC
CTTGGAGACTCATGGCTGCCCCGGCCAATCCCCAAAGTACCAGTATCTGCCCCAAGTTCCAGTGATCCCTGGACAGGAAGAGAATTAACC
AACCGGCACTCACTTCCATTTTCATTGCCCTCACAAATGGAGCCCAGACCAGATGTGCCTAGGCTCGGAAGCACGTTCAGTCTGGATACC
TCCATGAGTATGAATAGCAGCCCATTAGTAGGTCCAGAGTGTGACCACCCCAAAATCAAACCTTCCTCATCTGCCAATGCCATTTATTCT
CTGGCTGCCAGACCTCTTCCTGTGCCAAAACTGCCACCTGGGGAGCAATGTGAGGGTGAAGAGGACACAGAGTACATGACTCCCTCTTCC
AGGCCTCTACGGCCTTTGGATACATCCCAGAGTTCACGAGCATGTGATTGCGACCAGCAGATTGATAGCTGTACGTATGAAGCAATGTAT
AATATTCAGTCCCAGGCGCCATCTATCACCGAGAGCAGCACCTTTGGTGAAGGGAATTTGGCCGCAGCCCATGCCAACACTGGTCCCGAG
GAGTCAGAAAATGAGGATGATGGGTATGATGTCCCAAAGCCACCTGTGCCGGCCGTGCTGGCCCGCCGAACTCTCTCAGATATCTCTAAT
GCCAGCTCCTCCTTTGGCTGGTTGTCTCTGGATGGTGATCCTACAACAAATGTCACTGAAGGTTCCCAAGTTCCCGAGAGGCCTCCAAAA
CCATTCCCGCGGAGAATCAACTCTGAACGGAAAGCTGGCAGCTGTCAGCAAGGTAGTGGTCCTGCCGCCTCTGCTGCCACCGCCTCACCT
CAGCTCTCCAGTGAGATCGAGAACCTCATGAGTCAGGGGTACTCCTACCAGGACATCCAGAAAGCTTTGGTCATTGCCCAGAACAACATC
GAGATGGCCAAAAACATCCTCCGGGAATTTGTTTCCATTTCTTCTCCTGCCCATGTAGCTACCTAGCACACCATCTCCCTGCTGCAGGTT
TAGAGGACCAGTGAGTTGGGAGTTATTACTCAAGTGGCACCTAGAAGGGCAGGAGTTCCTTTGGTGACTTCACAGTGAAGTCTTGCCCTC
TCTGTGGGATATCACATCAGTGGTTCCAAGATTTCAAAGTGGTGAAATGAAAATGGAGCAGCTAGTATGTTTTATTATTTTATGGGTCTT
GAGTGCATTTGAAGGTGTCCTTCAGTTCCCACGTAGAGAGAGTGTGGATTATATTACATGATAACCTACCTGGGGAACAGTCCAGAAAGC
TATAGAACAAGTATTTTGCTGGAAATCCTAATTGAGGACTTAAGACTTCCTGGGTTAAGGATGTGGCCGTGTGTGTGTGTGTCTGCCTGT
GGTTGTATGTGTCCTTGTGATTATAAGATTAACCTGCTGTGTGTGTTAATTCCAGGCAGGGAATTAGCACAAAAGGTTTAGGAAGGAATC
TTTTTTTAAAGACTTCCATCTACTGTGGTATTATACCCAAGCCTAGTGTGTATTACAACTTCAACACTCCCCTTTGGCTTATATTACCAT
GTGCATAGCTAAAGTCTTCTATTTTTAGAACACCTTCTGTCTGTTCTTTCCCCATCAACTCCTTCCTCATCCTTCTTGGTGTTCTGTCAT
GGGCCATGGGCTTGCTATGGCCAGCCTTACTGAGGCCAAGCAGCTTATGGGATGTTCTTTATTGTGTGTGATGGTATTGGTTTGTTTGGT
AGATAAGTGGGAGGAAAAGTACTGTTGCTACACTATTATAGGCATGTTTGATACTAGCAGCTAACACTGGTCACTCCAAAGCACTGTTTC
TATAGGAACATTGAAGCTATTAAGATGTTTTGATTATCCTAATTACATAATGACCGATTTGAGATAGAGGCCTTTAAATACATTCCATGC
CCTCCCCAGAAAATAGTCTGTGGGAGTCAGTTGCCTTGGTGCCAGGTATGTGTTCTGATGTAGGTCATGAGTCTTTCTACTTAATGGGAA
GGGAAGAACATTTGTTTCCAGGATGACTTTCTGGCCAGAATACCGGAAAGCTTTTAGGAAGCTTCGTTCACATGCTATTTAAATGCACAA
AATAGACAGTAAGGATTTATCTGTTCAGTTTTTCTTCCCAGTGAATTAATTTCAGCTTATATGGGTGTCTTCATTTGAACATGAGGAATA
TTAGGTTATATTTTCAGCAGTGGTTTTTTCCTTTGCCCTTTAAGGAGTGGGGATAATGTCCACGGTGGCCCAGCCTCTTGCTGATGGCAC
CTTCCCTGCATTGCTGCCTCCCGATGATGTGGTTCTTTTCTTGTGCCTGTGGCTTTGGGAATGTAACATCTCTTTCCTCCTTTCCTTCCC
TTTTCCTCTTCACCTGAGGTCCTAAATACTCTCTGTAATTACTGTGTTCTTCACGGTAATTAGACATCATTCAGTGAATAAATTACTGTA
GTCAAAGACAGTATGGGCTGGCAGTTTGTGTAATTGCAAGTTCATAAAGAGAATTGAGGGTCCAGTTGGGAGAACTATTAGTCAGTTCTT
TTATATGCTGATAAATGATCCCTCGAGTTCAGTTAGTATTCTGTCCAGAGTGTTTAGCTCACTTTCTTAGCAGTGTGTAAGCTTTCTCCA
TGTCAGAAGCAAGCCTGCTCTTTGATAAATCTGTCTTCCTGAAAATCTAAATCATGCTTTTGTCTTTAGATCTACACAGAAATGACCCTC
CTTGGATCAGTTTTCTTTCCAGTCTAATCATCTTTGGAACTAAAACTTGTTCTAACTCGTCTCTTGGCATTCAGCTACTCCTAGATCTTT
TGGTTTTATCCCCTGGCCTCAGAGCCATTTATATTCCCAGAGTAGGCAGTACAGGATCTCGTGTTGATTTGCTGTGGTTACCCAGTGTCT
TCTCTACATGGCATAAAGCGGCAAAGCCCACCATTAGGTGAGGCGGTCCCGAGTTGAGGTAGAGTGGGGCAGAGGAAGATGGCAGTGAAT
ATCAAACAGTAGACCGCCATCAACTTCTAACAGCCAGTACACACACTGTTTCATTTTGAGGTAACGTTCAGTTTTGCATTTTGTTTAAAT
ATTGAAGGCCTAGACAAAGAACTAGAAAAAAAAAAGCAGTTTCCAGGCCCATCCATATTGTAATTTTTCTTTATCTGCAGATATTGCCTG
TAGTCTAAAGATCTCTTTGGAAGACAAAGCATTGGCTATATATCTTTTGCCTTTTCCATGCATCTAAATCTTCTCTGGAGATTATCTCCC
TACTGTGTAGGTTAAGGGCAGTCTCGACTTTTCCTTTTTTGAGTCCTGTGTGGCTCTTTGAATCAGCGTGAAACTGAGGCTCCAGCTCCC
TGTGTTGTGTGTGTGTGCCATCCATGGGCTTGGGTGTCAGTTTGTCACAGGTATCTGCCAGCATTCAAGGTTTTGGATCATTTCATGAGG
ATCTTTCCTTTGACTGGGTGCTGTGAGGACACACCTGGGTCTGTGCCTGAGATTGCCAGGCAAGATTAAGGAAAGTTTTCATGTGGCTTT
TGTTTTGAGGTTATTCTCAAAACCTTAATTTCTTATATTTTCTGTTGACTAAGGCACCAGTAACCCATTCTTCACCCTCCATTTGTATGG
CAATTTAAAAGTCTTTGGCTTTGCTCTGAATTTAATTAAAACTGCCTTTTATGAACAGACTTCGAGTTTTGCCATTTTGGGCAAGCCCTT
CCGCTTGTCCCTTCCTAGTGGCTAATAAAGTAAAAAAACCCACACTACTTTGTTCTCTTTTTCTCATATTCATTGGGCTGTTGTATTCAG
CCAGTCTCATGCTTTCCCTGGGTCTTCACGGATTGCTTTCCAAGCTGCCTTGTTGCGGGGTTGCTGCAGAGCAGCAACTGGACCTTTCCA
GCTGTCGCCATGTTCCTTCCACTAAAGTAGAGGGTTCTTAAAATGGAAAAACCTGTGGGCTCTTCATATACCTCCCTTTAGTTAAGTAAT
AGACCAGGCAGCTTCTCATCTCAGCATTTACCTGTTAATATTTTTGTGAATAGTGCTCTCTACCTGTGGGTGGCCGTTCTCTTCCACTTG
CTCGTCTCCCCCCAGCCCCATTCTGCATAATCTACCATTCTTCTCCTCTCTTTCTCTTCTTATACAGACCCTCATTACTGGGGCCCAAGA
TGTGGGATACTACTGTTAGTATTATTTAACTATTTTGTAGATTTAAAAGATTTCTGGTTAAGGGAGGTGGGGGTCACTGTTCATCACTCT
TAAAATATGTGTTTTCTCTATAGAAAAGTAAAATGTGTTTATGGTCCCAAACAGTCAACTCACAAATTTTTATAACAAAATTTCCTTGTA
AAAACTAGGGACCATCTATATATTCCCTTTAAGATCTAGTTCTTTTTGTAGGTGTTCAGCAATGGTGATAAAGCAGAATATTCTCCTACC
TCACGTCATTAAAGTCAGAAGATTATAGACCTTCTCAAACTATAAGTCCCTCTTCTTGCCGTTGGCCTTTCTGACTCTGGAATGACCACT
GTTCATTGAAAAATAGTTTTCTGACTATTGGTCTGGCTCTAACAGTTTGTTTGTTCATCCAGCAAATGTTTATGAGTGATGACCATGTGC
CAGAAATGTCAGGTATGTGTCCTTCCCTTGGCGCCACATAGTAGTTTACTAATGTTTGGGGGATTGTACTTGGACTGTCATAGCCTCTGC
GTTTGACCTTAAAATAGCTCTTCCCAGTAAGATTGTGCAATTTTTATTCACAGCTCTTCCATGTAGACTTACCTTTCCTCATAGAGCTAT
CCTGGTTAATAACAGGCCAAGATTCTCCCATTATCCCCTGTTGTCTCCTGTAGCTTTGATAATGCCTGGGAGATTCCTTGGTGTAAGTGT
CATGGATACCGACTGTTTTTATGTTGGAATTTGTTCCAACATAATTAGAATCTGTTTGGTGAGTTGAAAGGTAAGTTGGCTCAGAGTTGC
ACAGTAGGGCATTAAATGTTTAAGCAAAGCATCTGCCCACACTCCCCTTTCCAATCTAGTGCCTTCCTTGAACTTTTTCCTGAGCTGCTA
CGTCCCTAATCCCCCTTGTTGGGAGGATTTTCGTATCACCCTTATGGGACCTGTCACCATGTCCTGTACTATTTGGAATTGGTTTTCCAG
TCTTTCAACAACCGTTGTGGCTAACTATGTTTTAGAAGGGCTGGAGGTGTGGGCCCTGTCTTCGGGTCTCAGGACCCAAAGATCCTTTAG
TCAGTTGTTGGGTCTTCCAAGAGCCAGACATTAATACAGATTGAACTCCATCAGTCCCCTAATTGTCAGCCTTTACCTCCCTCCCAGAGC
AAGGAGTTTAGGGATTCTAAAGCTTAGTGTCCACACATCATTCTACCAGACCTTAGAGCTTTAGAAGCTCAATCTAAAATACTGTAACTC
AGCATAAACTATTACTATCACTCCTTTGAACTCAGTCTCCATGAGCAGTGTTTTGTTGGAAATACATAGAACGGCTTAATGCCTAGAGGG
TGGTGGATAGTGAAGGACGGTCAAGGTTATATTTTTGACTGCTTAGGGATTCTTTGGATCCAAGAAACAGAAATGTTCAAGCGGAATAAA
GGAGGGAGTGGAGTTGTGGTAAGGATGCAGGGTATTTCGCAGAACCCAGGACGGGAAGTGCCTTTGGTTCTTGGGTGGAGCTGGAACTGC
AGAGCTTTGCACCTAGTCCTTTCTCCCGCTTCACAGTCTGCTTATGGTATATGTGGCCCCCAAATAGGCACTCTAGTCCTCAAGTCTACA
CCACCTTCCAACTCTGGGGATCACCATGAACAAATTCTCAATTTCCCATACTTAATTTTTTTTTTTTTTGAGATGGAGTCTCGCTGTGTC
GCCCAGGCTGGAGTGCAGTGGTGCAGTCTCAACTCACCACAACCTCTGCCTCCCAGGTTCAAGCAGTTCTCTGCCTCAACCTCCCGAGTA
GCTGGGATTACAGGCGCCTGCCACCATGCCCAGCTAATGTTCATATTTTTAGTAGAGACAGGGTTTCACCGTCTTGGCTAGGCTGGTCTT
GAACTCCTGACCCTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTAAGATTACAGGCGTGAGCCACCGCGCCCGGCCCATACTTCGTA
TTCTTAAAAAAAACTACACTCAGCCCAGCACATTGATCAAGTATCTATCTCTGAGCAGTTGGCCTTGCCAGGGAGAGCAGAGATGTGGCA
GGCTCCTTCAGCTGGAGACAGGGAGCTTCTCAGAGAAGTGAGCAGAGACTCCACAGACACCCTAAAAAGGCTTCTACTCAAGAAGTAAAG
CCACTACTCCTGCCTTTTTGCTTAGTGGACAGGAAGGCACAGGAGTTTGTCTGGGACATCATAGAAATTCTTAGGTTTAACTTAATTCTG
GTCATTGTCTTCTTTATTTCCTGTTTTTCTTCCCTTTGTCAGTCTTCGCATCCAAGATTTCTTCCCTCCCTCTTGTGGGCCAGCCTGTCC
TGTTCCAGAGCTAGCCTGTTCCTGGGTAGCCTTCCTTAGCCTCCATTCAGCCTCAGGTCTTTTGCCTTCTTCCGTGTTTATTTAGAGAGC
AGAATCTAATAACGGGTTCCACTGTAGCCACTATCCATGGACTTCTGGGTCCTCTTCAGGTTTGAGTGCTTGAAAATGTTCATTCTCTGG
GCTTGTGGCCTGTCTCCTCCACTCTCCTCCTCACCCTCTCGCTCCTTCCTGTGTGAGGGCCGCTCTGCAGTAATGTTCTCAGGCAAGCCT
TCCTAGGCACCTCAGAAACTACTTTGCCAGAGCCAGTAAGAATATATAATATTGGAGCAGTTGCCAGGATAGAAATTAAATATAGATTCC
AGTTTAGGATAGAGTTTTTACCGAGAGCTCTTTAGACAGTATACCTGTGTCTTCTCTGGCAATTGCTTTCATTTTAGTCCTATATAAAAG
CTTTCCTTTTCTGTTTTTTTTTAAAACTATGCTTTTGCTTGCCTAAATCTTTTGATCTTATATTTCTCTCATCTCAGAGCCTGTCCTGAG
TTGTAAGGTATTTCATACTGCCTTACTTAAAAGTTTTTTAAACTACTAGAGTCATTTGATACACACAGAAGTTACCTAATAATCCAAAGA
TGTCCATCAAGGGAGGAAGGGTGGGTCATCAGACTTTGCCTTTGATGTTGTAGACTAGGCTCCTGAGTTAAGCAGCAGAGGGACAGCAGT
GCCATGTGCCTTCACTGTGTCCCAGGAAATCTGGGTTGGTTCCAGTGGGAAATACCAGTATTTCTTGGTTCTGGAAAGTAGCAAAAGAGT
AGGAGATGGGGAAATAGGGATGGGGAGAGCAAGCCCCGCATGTCCATGGCGAGTCAGGTGGGGAGCACGGGTGGAAGGGCCGGCTGTTGA
CAGACAGACTAAGCTGTGTGGTGCTCTTGCCGCCCCTTCCTGGGTACAGAGCTTGAGAAAAATGCAGCCGACCACTCCCTGTGTTTGTAC
AGAGCAAAGCCCAAAAGCCAACCTCAGATCTCCTGATTTGGCAGCTGAAGAAATCAGCAGAGTCCTGATTGCCTGATTCAGTCCCAAAAA
TGAATGTCAGGCCCCGCCCCCTCCCCACCAACATTGCCTCTCCTACATTCTCCTTCTGCCCCTAAATCAGACAGGAGGCCAGAGAGGAGT
ATTGCTCAATGCGTGCTATGTGCAACTCCTCAGGCCTTGTGCCACCTCCATGCTGAGCCCTGAAGCAGGGTGTCCTGGGTGCCTGTGTGT
CAGCTCCCTCCTCTCTACCTACCTCTGACCTTCTTGTGGGTGAGGGTGGCCATGCTTATGGCCATCTTAAAACTGGAGAGGCAGAGAACT
ACTTATGAGTCTGTAGACCACGTGTTGTCTTCCATGGCCTGTTTCTCCTGCTGTCTGGGTGAGTGAGCCTGCAACGCAATGCCCATGAGA
GTAAATGCCTCCTGACCTACCCTGCTCAGCACTGTTCTAGTGTCTTGGCCTTGAAAGAAAAGCCTGACTTCCTGCTGACACATGTGGTAG
GGGCATGGCAGCTATGAGGCACCTCCTACGTCTGTTTTCTGGCTGTGGTGACTTGGGATTTTTAACCTTATATATCTTTTTCCTTTACTC
AAAACAAAACAATTTTTAGCACACTGAAAAAAAAAAAAAGCCAAATGTTTTGTGCCTTTCTAAGGCAGCACTGTATCCCAGGCTGCATTT
TAGGACTTAATATGGAAATACCAGAGTCTGAGCTCCTCTACCTTGAGTTTCATTAGTCCTTAGTGTCTAGGAGACAGGAAAGAATGCTCT
CTGTGACTGGAGAGGTGACATGCAGGTGCAGTGTGTCTGGAGTCCCTTTCCCCTGCTGTGAGACTTCAGTGGAGGAGAGAAGCATTGTAC
CCTGGGATCATTTGGTTGGTTCCAATCACAAGCTTAGTTATCAGGTTGCATGCCTTGTCTCCTGCAAAAGACAGAATGTTTCACAATTCC
CAGGTAAACTCTGGACCATTCCAAGTGTCCTAGCCTTCTGATGACATTAATTACCTAGTTGTGTCGAGGAGTATAGGATGGACTCTCCTG
AGAAGGGGAGGTTGGTGGCTTTGTCTTTTCTTTTTGCTGGATCCTGAACTGGTCTAGACCTCCTGCCCCCACCCCCCAGCCCCCATCAGA
TGTGGCTGGCCTTTCATTTGAAGGCTTCAGACTTAAAGCATTAAGCAGCTAGTGCCCTCTGCAGGGCCTGGTTTCCCCAGGGAAGGGCAG
CAAGGAACATGGGACCAGAAGCCTGTCCTCAGTAATGTGACTATAGTGAGCTTTAGCAAAAGTTTTTCTATATAATGACATCTTACTTAT
CTTTTACCCTTTCCTCAGTTTTCCCCTGCCTTTAACTAATAAAGAATTGGGAGACAGAAATTTTAAAGTCCTCCTTATTCAAGATTTTGA
AATTCTTAGCCTGGGAGTGCTGGAGAGAACCTGATGCTTTCTCCAGAATGAAGAGTCCCAATTTGTATATCAGTGTTAAGAAGAAAACAA
AACAAACACATAGGTGAGATTTTCGTGGACTATTTTAAAAATGTGTCATTAATATAAAAAATTTATATTAGCAGTATTTAATCATTCTCA
CCTGTAAAGAATAAGAAAAACAGAAGGTAAATATTCTTACAGAGAATAGCAGAGCTTTAAGATTCATTTTCATTTTAAGTCCATTTTATT
TTGCCAGTGTATTAATGTTTAGAAGTCTGTTTTACTAATGTTATTTATTAATTTTTTTTCATTTCCATACACAGTTAGTTAACTAAAGAG

>43149_43149_2_KMT2A-CBL_KMT2A_chr11_118353210_ENST00000389506_CBL_chr11_119155678_ENST00000264033_length(amino acids)=1791AA_BP=7
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVG
AESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDT
SMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMY
NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPK

--------------------------------------------------------------
>43149_43149_3_KMT2A-CBL_KMT2A_chr11_118353210_ENST00000534358_CBL_chr11_119155678_ENST00000264033_length(transcript)=13767nt_BP=4109nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGTGGAACGGCCGCCTTCTCCATTCTCCATGG
CCCCACAAGCTTCCCTTCCCCCGGTGCCACCACGACTTGACCTTCTGCCGCAGCGAGTATGTGTTCCCTCAAGTGCTTCTGCTCTTGGAA
CTGCTTCTAAGGCTGCTTCTGGCTCCCTTCATAAAGACAAACCATTGCCAGTACCTCCCACACTTCGAGATCTTCCACCACCACCGCCTC
CAGACCGGCCATATTCTGTTGGAGCAGAATCCCGACCTCAAAGACGCCCCTTGCCTTGTACACCAGGCGACTGTCCCTCCAGAGACAAAC
TGCCCCCTGTCCCCTCTAGCCGCCTTGGAGACTCATGGCTGCCCCGGCCAATCCCCAAAGTACCAGTATCTGCCCCAAGTTCCAGTGATC
CCTGGACAGGAAGAGAATTAACCAACCGGCACTCACTTCCATTTTCATTGCCCTCACAAATGGAGCCCAGACCAGATGTGCCTAGGCTCG
GAAGCACGTTCAGTCTGGATACCTCCATGAGTATGAATAGCAGCCCATTAGTAGGTCCAGAGTGTGACCACCCCAAAATCAAACCTTCCT
CATCTGCCAATGCCATTTATTCTCTGGCTGCCAGACCTCTTCCTGTGCCAAAACTGCCACCTGGGGAGCAATGTGAGGGTGAAGAGGACA
CAGAGTACATGACTCCCTCTTCCAGGCCTCTACGGCCTTTGGATACATCCCAGAGTTCACGAGCATGTGATTGCGACCAGCAGATTGATA
GCTGTACGTATGAAGCAATGTATAATATTCAGTCCCAGGCGCCATCTATCACCGAGAGCAGCACCTTTGGTGAAGGGAATTTGGCCGCAG
CCCATGCCAACACTGGTCCCGAGGAGTCAGAAAATGAGGATGATGGGTATGATGTCCCAAAGCCACCTGTGCCGGCCGTGCTGGCCCGCC
GAACTCTCTCAGATATCTCTAATGCCAGCTCCTCCTTTGGCTGGTTGTCTCTGGATGGTGATCCTACAACAAATGTCACTGAAGGTTCCC
AAGTTCCCGAGAGGCCTCCAAAACCATTCCCGCGGAGAATCAACTCTGAACGGAAAGCTGGCAGCTGTCAGCAAGGTAGTGGTCCTGCCG
CCTCTGCTGCCACCGCCTCACCTCAGCTCTCCAGTGAGATCGAGAACCTCATGAGTCAGGGGTACTCCTACCAGGACATCCAGAAAGCTT
TGGTCATTGCCCAGAACAACATCGAGATGGCCAAAAACATCCTCCGGGAATTTGTTTCCATTTCTTCTCCTGCCCATGTAGCTACCTAGC
ACACCATCTCCCTGCTGCAGGTTTAGAGGACCAGTGAGTTGGGAGTTATTACTCAAGTGGCACCTAGAAGGGCAGGAGTTCCTTTGGTGA
CTTCACAGTGAAGTCTTGCCCTCTCTGTGGGATATCACATCAGTGGTTCCAAGATTTCAAAGTGGTGAAATGAAAATGGAGCAGCTAGTA
TGTTTTATTATTTTATGGGTCTTGAGTGCATTTGAAGGTGTCCTTCAGTTCCCACGTAGAGAGAGTGTGGATTATATTACATGATAACCT
ACCTGGGGAACAGTCCAGAAAGCTATAGAACAAGTATTTTGCTGGAAATCCTAATTGAGGACTTAAGACTTCCTGGGTTAAGGATGTGGC
CGTGTGTGTGTGTGTCTGCCTGTGGTTGTATGTGTCCTTGTGATTATAAGATTAACCTGCTGTGTGTGTTAATTCCAGGCAGGGAATTAG
CACAAAAGGTTTAGGAAGGAATCTTTTTTTAAAGACTTCCATCTACTGTGGTATTATACCCAAGCCTAGTGTGTATTACAACTTCAACAC
TCCCCTTTGGCTTATATTACCATGTGCATAGCTAAAGTCTTCTATTTTTAGAACACCTTCTGTCTGTTCTTTCCCCATCAACTCCTTCCT
CATCCTTCTTGGTGTTCTGTCATGGGCCATGGGCTTGCTATGGCCAGCCTTACTGAGGCCAAGCAGCTTATGGGATGTTCTTTATTGTGT
GTGATGGTATTGGTTTGTTTGGTAGATAAGTGGGAGGAAAAGTACTGTTGCTACACTATTATAGGCATGTTTGATACTAGCAGCTAACAC
TGGTCACTCCAAAGCACTGTTTCTATAGGAACATTGAAGCTATTAAGATGTTTTGATTATCCTAATTACATAATGACCGATTTGAGATAG
AGGCCTTTAAATACATTCCATGCCCTCCCCAGAAAATAGTCTGTGGGAGTCAGTTGCCTTGGTGCCAGGTATGTGTTCTGATGTAGGTCA
TGAGTCTTTCTACTTAATGGGAAGGGAAGAACATTTGTTTCCAGGATGACTTTCTGGCCAGAATACCGGAAAGCTTTTAGGAAGCTTCGT
TCACATGCTATTTAAATGCACAAAATAGACAGTAAGGATTTATCTGTTCAGTTTTTCTTCCCAGTGAATTAATTTCAGCTTATATGGGTG
TCTTCATTTGAACATGAGGAATATTAGGTTATATTTTCAGCAGTGGTTTTTTCCTTTGCCCTTTAAGGAGTGGGGATAATGTCCACGGTG
GCCCAGCCTCTTGCTGATGGCACCTTCCCTGCATTGCTGCCTCCCGATGATGTGGTTCTTTTCTTGTGCCTGTGGCTTTGGGAATGTAAC
ATCTCTTTCCTCCTTTCCTTCCCTTTTCCTCTTCACCTGAGGTCCTAAATACTCTCTGTAATTACTGTGTTCTTCACGGTAATTAGACAT
CATTCAGTGAATAAATTACTGTAGTCAAAGACAGTATGGGCTGGCAGTTTGTGTAATTGCAAGTTCATAAAGAGAATTGAGGGTCCAGTT
GGGAGAACTATTAGTCAGTTCTTTTATATGCTGATAAATGATCCCTCGAGTTCAGTTAGTATTCTGTCCAGAGTGTTTAGCTCACTTTCT
TAGCAGTGTGTAAGCTTTCTCCATGTCAGAAGCAAGCCTGCTCTTTGATAAATCTGTCTTCCTGAAAATCTAAATCATGCTTTTGTCTTT
AGATCTACACAGAAATGACCCTCCTTGGATCAGTTTTCTTTCCAGTCTAATCATCTTTGGAACTAAAACTTGTTCTAACTCGTCTCTTGG
CATTCAGCTACTCCTAGATCTTTTGGTTTTATCCCCTGGCCTCAGAGCCATTTATATTCCCAGAGTAGGCAGTACAGGATCTCGTGTTGA
TTTGCTGTGGTTACCCAGTGTCTTCTCTACATGGCATAAAGCGGCAAAGCCCACCATTAGGTGAGGCGGTCCCGAGTTGAGGTAGAGTGG
GGCAGAGGAAGATGGCAGTGAATATCAAACAGTAGACCGCCATCAACTTCTAACAGCCAGTACACACACTGTTTCATTTTGAGGTAACGT
TCAGTTTTGCATTTTGTTTAAATATTGAAGGCCTAGACAAAGAACTAGAAAAAAAAAAGCAGTTTCCAGGCCCATCCATATTGTAATTTT
TCTTTATCTGCAGATATTGCCTGTAGTCTAAAGATCTCTTTGGAAGACAAAGCATTGGCTATATATCTTTTGCCTTTTCCATGCATCTAA
ATCTTCTCTGGAGATTATCTCCCTACTGTGTAGGTTAAGGGCAGTCTCGACTTTTCCTTTTTTGAGTCCTGTGTGGCTCTTTGAATCAGC
GTGAAACTGAGGCTCCAGCTCCCTGTGTTGTGTGTGTGTGCCATCCATGGGCTTGGGTGTCAGTTTGTCACAGGTATCTGCCAGCATTCA
AGGTTTTGGATCATTTCATGAGGATCTTTCCTTTGACTGGGTGCTGTGAGGACACACCTGGGTCTGTGCCTGAGATTGCCAGGCAAGATT
AAGGAAAGTTTTCATGTGGCTTTTGTTTTGAGGTTATTCTCAAAACCTTAATTTCTTATATTTTCTGTTGACTAAGGCACCAGTAACCCA
TTCTTCACCCTCCATTTGTATGGCAATTTAAAAGTCTTTGGCTTTGCTCTGAATTTAATTAAAACTGCCTTTTATGAACAGACTTCGAGT
TTTGCCATTTTGGGCAAGCCCTTCCGCTTGTCCCTTCCTAGTGGCTAATAAAGTAAAAAAACCCACACTACTTTGTTCTCTTTTTCTCAT
ATTCATTGGGCTGTTGTATTCAGCCAGTCTCATGCTTTCCCTGGGTCTTCACGGATTGCTTTCCAAGCTGCCTTGTTGCGGGGTTGCTGC
AGAGCAGCAACTGGACCTTTCCAGCTGTCGCCATGTTCCTTCCACTAAAGTAGAGGGTTCTTAAAATGGAAAAACCTGTGGGCTCTTCAT
ATACCTCCCTTTAGTTAAGTAATAGACCAGGCAGCTTCTCATCTCAGCATTTACCTGTTAATATTTTTGTGAATAGTGCTCTCTACCTGT
GGGTGGCCGTTCTCTTCCACTTGCTCGTCTCCCCCCAGCCCCATTCTGCATAATCTACCATTCTTCTCCTCTCTTTCTCTTCTTATACAG
ACCCTCATTACTGGGGCCCAAGATGTGGGATACTACTGTTAGTATTATTTAACTATTTTGTAGATTTAAAAGATTTCTGGTTAAGGGAGG
TGGGGGTCACTGTTCATCACTCTTAAAATATGTGTTTTCTCTATAGAAAAGTAAAATGTGTTTATGGTCCCAAACAGTCAACTCACAAAT
TTTTATAACAAAATTTCCTTGTAAAAACTAGGGACCATCTATATATTCCCTTTAAGATCTAGTTCTTTTTGTAGGTGTTCAGCAATGGTG
ATAAAGCAGAATATTCTCCTACCTCACGTCATTAAAGTCAGAAGATTATAGACCTTCTCAAACTATAAGTCCCTCTTCTTGCCGTTGGCC
TTTCTGACTCTGGAATGACCACTGTTCATTGAAAAATAGTTTTCTGACTATTGGTCTGGCTCTAACAGTTTGTTTGTTCATCCAGCAAAT
GTTTATGAGTGATGACCATGTGCCAGAAATGTCAGGTATGTGTCCTTCCCTTGGCGCCACATAGTAGTTTACTAATGTTTGGGGGATTGT
ACTTGGACTGTCATAGCCTCTGCGTTTGACCTTAAAATAGCTCTTCCCAGTAAGATTGTGCAATTTTTATTCACAGCTCTTCCATGTAGA
CTTACCTTTCCTCATAGAGCTATCCTGGTTAATAACAGGCCAAGATTCTCCCATTATCCCCTGTTGTCTCCTGTAGCTTTGATAATGCCT
GGGAGATTCCTTGGTGTAAGTGTCATGGATACCGACTGTTTTTATGTTGGAATTTGTTCCAACATAATTAGAATCTGTTTGGTGAGTTGA
AAGGTAAGTTGGCTCAGAGTTGCACAGTAGGGCATTAAATGTTTAAGCAAAGCATCTGCCCACACTCCCCTTTCCAATCTAGTGCCTTCC
TTGAACTTTTTCCTGAGCTGCTACGTCCCTAATCCCCCTTGTTGGGAGGATTTTCGTATCACCCTTATGGGACCTGTCACCATGTCCTGT
ACTATTTGGAATTGGTTTTCCAGTCTTTCAACAACCGTTGTGGCTAACTATGTTTTAGAAGGGCTGGAGGTGTGGGCCCTGTCTTCGGGT
CTCAGGACCCAAAGATCCTTTAGTCAGTTGTTGGGTCTTCCAAGAGCCAGACATTAATACAGATTGAACTCCATCAGTCCCCTAATTGTC
AGCCTTTACCTCCCTCCCAGAGCAAGGAGTTTAGGGATTCTAAAGCTTAGTGTCCACACATCATTCTACCAGACCTTAGAGCTTTAGAAG
CTCAATCTAAAATACTGTAACTCAGCATAAACTATTACTATCACTCCTTTGAACTCAGTCTCCATGAGCAGTGTTTTGTTGGAAATACAT
AGAACGGCTTAATGCCTAGAGGGTGGTGGATAGTGAAGGACGGTCAAGGTTATATTTTTGACTGCTTAGGGATTCTTTGGATCCAAGAAA
CAGAAATGTTCAAGCGGAATAAAGGAGGGAGTGGAGTTGTGGTAAGGATGCAGGGTATTTCGCAGAACCCAGGACGGGAAGTGCCTTTGG
TTCTTGGGTGGAGCTGGAACTGCAGAGCTTTGCACCTAGTCCTTTCTCCCGCTTCACAGTCTGCTTATGGTATATGTGGCCCCCAAATAG
GCACTCTAGTCCTCAAGTCTACACCACCTTCCAACTCTGGGGATCACCATGAACAAATTCTCAATTTCCCATACTTAATTTTTTTTTTTT
TTGAGATGGAGTCTCGCTGTGTCGCCCAGGCTGGAGTGCAGTGGTGCAGTCTCAACTCACCACAACCTCTGCCTCCCAGGTTCAAGCAGT
TCTCTGCCTCAACCTCCCGAGTAGCTGGGATTACAGGCGCCTGCCACCATGCCCAGCTAATGTTCATATTTTTAGTAGAGACAGGGTTTC
ACCGTCTTGGCTAGGCTGGTCTTGAACTCCTGACCCTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTAAGATTACAGGCGTGAGCCA
CCGCGCCCGGCCCATACTTCGTATTCTTAAAAAAAACTACACTCAGCCCAGCACATTGATCAAGTATCTATCTCTGAGCAGTTGGCCTTG
CCAGGGAGAGCAGAGATGTGGCAGGCTCCTTCAGCTGGAGACAGGGAGCTTCTCAGAGAAGTGAGCAGAGACTCCACAGACACCCTAAAA
AGGCTTCTACTCAAGAAGTAAAGCCACTACTCCTGCCTTTTTGCTTAGTGGACAGGAAGGCACAGGAGTTTGTCTGGGACATCATAGAAA
TTCTTAGGTTTAACTTAATTCTGGTCATTGTCTTCTTTATTTCCTGTTTTTCTTCCCTTTGTCAGTCTTCGCATCCAAGATTTCTTCCCT
CCCTCTTGTGGGCCAGCCTGTCCTGTTCCAGAGCTAGCCTGTTCCTGGGTAGCCTTCCTTAGCCTCCATTCAGCCTCAGGTCTTTTGCCT
TCTTCCGTGTTTATTTAGAGAGCAGAATCTAATAACGGGTTCCACTGTAGCCACTATCCATGGACTTCTGGGTCCTCTTCAGGTTTGAGT
GCTTGAAAATGTTCATTCTCTGGGCTTGTGGCCTGTCTCCTCCACTCTCCTCCTCACCCTCTCGCTCCTTCCTGTGTGAGGGCCGCTCTG
CAGTAATGTTCTCAGGCAAGCCTTCCTAGGCACCTCAGAAACTACTTTGCCAGAGCCAGTAAGAATATATAATATTGGAGCAGTTGCCAG
GATAGAAATTAAATATAGATTCCAGTTTAGGATAGAGTTTTTACCGAGAGCTCTTTAGACAGTATACCTGTGTCTTCTCTGGCAATTGCT
TTCATTTTAGTCCTATATAAAAGCTTTCCTTTTCTGTTTTTTTTTAAAACTATGCTTTTGCTTGCCTAAATCTTTTGATCTTATATTTCT
CTCATCTCAGAGCCTGTCCTGAGTTGTAAGGTATTTCATACTGCCTTACTTAAAAGTTTTTTAAACTACTAGAGTCATTTGATACACACA
GAAGTTACCTAATAATCCAAAGATGTCCATCAAGGGAGGAAGGGTGGGTCATCAGACTTTGCCTTTGATGTTGTAGACTAGGCTCCTGAG
TTAAGCAGCAGAGGGACAGCAGTGCCATGTGCCTTCACTGTGTCCCAGGAAATCTGGGTTGGTTCCAGTGGGAAATACCAGTATTTCTTG
GTTCTGGAAAGTAGCAAAAGAGTAGGAGATGGGGAAATAGGGATGGGGAGAGCAAGCCCCGCATGTCCATGGCGAGTCAGGTGGGGAGCA
CGGGTGGAAGGGCCGGCTGTTGACAGACAGACTAAGCTGTGTGGTGCTCTTGCCGCCCCTTCCTGGGTACAGAGCTTGAGAAAAATGCAG
CCGACCACTCCCTGTGTTTGTACAGAGCAAAGCCCAAAAGCCAACCTCAGATCTCCTGATTTGGCAGCTGAAGAAATCAGCAGAGTCCTG
ATTGCCTGATTCAGTCCCAAAAATGAATGTCAGGCCCCGCCCCCTCCCCACCAACATTGCCTCTCCTACATTCTCCTTCTGCCCCTAAAT
CAGACAGGAGGCCAGAGAGGAGTATTGCTCAATGCGTGCTATGTGCAACTCCTCAGGCCTTGTGCCACCTCCATGCTGAGCCCTGAAGCA
GGGTGTCCTGGGTGCCTGTGTGTCAGCTCCCTCCTCTCTACCTACCTCTGACCTTCTTGTGGGTGAGGGTGGCCATGCTTATGGCCATCT
TAAAACTGGAGAGGCAGAGAACTACTTATGAGTCTGTAGACCACGTGTTGTCTTCCATGGCCTGTTTCTCCTGCTGTCTGGGTGAGTGAG
CCTGCAACGCAATGCCCATGAGAGTAAATGCCTCCTGACCTACCCTGCTCAGCACTGTTCTAGTGTCTTGGCCTTGAAAGAAAAGCCTGA
CTTCCTGCTGACACATGTGGTAGGGGCATGGCAGCTATGAGGCACCTCCTACGTCTGTTTTCTGGCTGTGGTGACTTGGGATTTTTAACC
TTATATATCTTTTTCCTTTACTCAAAACAAAACAATTTTTAGCACACTGAAAAAAAAAAAAAGCCAAATGTTTTGTGCCTTTCTAAGGCA
GCACTGTATCCCAGGCTGCATTTTAGGACTTAATATGGAAATACCAGAGTCTGAGCTCCTCTACCTTGAGTTTCATTAGTCCTTAGTGTC
TAGGAGACAGGAAAGAATGCTCTCTGTGACTGGAGAGGTGACATGCAGGTGCAGTGTGTCTGGAGTCCCTTTCCCCTGCTGTGAGACTTC
AGTGGAGGAGAGAAGCATTGTACCCTGGGATCATTTGGTTGGTTCCAATCACAAGCTTAGTTATCAGGTTGCATGCCTTGTCTCCTGCAA
AAGACAGAATGTTTCACAATTCCCAGGTAAACTCTGGACCATTCCAAGTGTCCTAGCCTTCTGATGACATTAATTACCTAGTTGTGTCGA
GGAGTATAGGATGGACTCTCCTGAGAAGGGGAGGTTGGTGGCTTTGTCTTTTCTTTTTGCTGGATCCTGAACTGGTCTAGACCTCCTGCC
CCCACCCCCCAGCCCCCATCAGATGTGGCTGGCCTTTCATTTGAAGGCTTCAGACTTAAAGCATTAAGCAGCTAGTGCCCTCTGCAGGGC
CTGGTTTCCCCAGGGAAGGGCAGCAAGGAACATGGGACCAGAAGCCTGTCCTCAGTAATGTGACTATAGTGAGCTTTAGCAAAAGTTTTT
CTATATAATGACATCTTACTTATCTTTTACCCTTTCCTCAGTTTTCCCCTGCCTTTAACTAATAAAGAATTGGGAGACAGAAATTTTAAA
GTCCTCCTTATTCAAGATTTTGAAATTCTTAGCCTGGGAGTGCTGGAGAGAACCTGATGCTTTCTCCAGAATGAAGAGTCCCAATTTGTA
TATCAGTGTTAAGAAGAAAACAAAACAAACACATAGGTGAGATTTTCGTGGACTATTTTAAAAATGTGTCATTAATATAAAAAATTTATA
TTAGCAGTATTTAATCATTCTCACCTGTAAAGAATAAGAAAAACAGAAGGTAAATATTCTTACAGAGAATAGCAGAGCTTTAAGATTCAT
TTTCATTTTAAGTCCATTTTATTTTGCCAGTGTATTAATGTTTAGAAGTCTGTTTTACTAATGTTATTTATTAATTTTTTTTCATTTCCA

>43149_43149_3_KMT2A-CBL_KMT2A_chr11_118353210_ENST00000534358_CBL_chr11_119155678_ENST00000264033_length(amino acids)=1791AA_BP=7
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVG
AESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDT
SMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMY
NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPK

--------------------------------------------------------------
>43149_43149_4_KMT2A-CBL_KMT2A_chr11_118353213_ENST00000354520_CBL_chr11_119155677_ENST00000264033_length(transcript)=13744nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGTGGAACGGCCGCCTTCTCCATTCTCCATGGCCCCACAAGCTTCCCTTCCCCCG
GTGCCACCACGACTTGACCTTCTGCCGCAGCGAGTATGTGTTCCCTCAAGTGCTTCTGCTCTTGGAACTGCTTCTAAGGCTGCTTCTGGC
TCCCTTCATAAAGACAAACCATTGCCAGTACCTCCCACACTTCGAGATCTTCCACCACCACCGCCTCCAGACCGGCCATATTCTGTTGGA
GCAGAATCCCGACCTCAAAGACGCCCCTTGCCTTGTACACCAGGCGACTGTCCCTCCAGAGACAAACTGCCCCCTGTCCCCTCTAGCCGC
CTTGGAGACTCATGGCTGCCCCGGCCAATCCCCAAAGTACCAGTATCTGCCCCAAGTTCCAGTGATCCCTGGACAGGAAGAGAATTAACC
AACCGGCACTCACTTCCATTTTCATTGCCCTCACAAATGGAGCCCAGACCAGATGTGCCTAGGCTCGGAAGCACGTTCAGTCTGGATACC
TCCATGAGTATGAATAGCAGCCCATTAGTAGGTCCAGAGTGTGACCACCCCAAAATCAAACCTTCCTCATCTGCCAATGCCATTTATTCT
CTGGCTGCCAGACCTCTTCCTGTGCCAAAACTGCCACCTGGGGAGCAATGTGAGGGTGAAGAGGACACAGAGTACATGACTCCCTCTTCC
AGGCCTCTACGGCCTTTGGATACATCCCAGAGTTCACGAGCATGTGATTGCGACCAGCAGATTGATAGCTGTACGTATGAAGCAATGTAT
AATATTCAGTCCCAGGCGCCATCTATCACCGAGAGCAGCACCTTTGGTGAAGGGAATTTGGCCGCAGCCCATGCCAACACTGGTCCCGAG
GAGTCAGAAAATGAGGATGATGGGTATGATGTCCCAAAGCCACCTGTGCCGGCCGTGCTGGCCCGCCGAACTCTCTCAGATATCTCTAAT
GCCAGCTCCTCCTTTGGCTGGTTGTCTCTGGATGGTGATCCTACAACAAATGTCACTGAAGGTTCCCAAGTTCCCGAGAGGCCTCCAAAA
CCATTCCCGCGGAGAATCAACTCTGAACGGAAAGCTGGCAGCTGTCAGCAAGGTAGTGGTCCTGCCGCCTCTGCTGCCACCGCCTCACCT
CAGCTCTCCAGTGAGATCGAGAACCTCATGAGTCAGGGGTACTCCTACCAGGACATCCAGAAAGCTTTGGTCATTGCCCAGAACAACATC
GAGATGGCCAAAAACATCCTCCGGGAATTTGTTTCCATTTCTTCTCCTGCCCATGTAGCTACCTAGCACACCATCTCCCTGCTGCAGGTT
TAGAGGACCAGTGAGTTGGGAGTTATTACTCAAGTGGCACCTAGAAGGGCAGGAGTTCCTTTGGTGACTTCACAGTGAAGTCTTGCCCTC
TCTGTGGGATATCACATCAGTGGTTCCAAGATTTCAAAGTGGTGAAATGAAAATGGAGCAGCTAGTATGTTTTATTATTTTATGGGTCTT
GAGTGCATTTGAAGGTGTCCTTCAGTTCCCACGTAGAGAGAGTGTGGATTATATTACATGATAACCTACCTGGGGAACAGTCCAGAAAGC
TATAGAACAAGTATTTTGCTGGAAATCCTAATTGAGGACTTAAGACTTCCTGGGTTAAGGATGTGGCCGTGTGTGTGTGTGTCTGCCTGT
GGTTGTATGTGTCCTTGTGATTATAAGATTAACCTGCTGTGTGTGTTAATTCCAGGCAGGGAATTAGCACAAAAGGTTTAGGAAGGAATC
TTTTTTTAAAGACTTCCATCTACTGTGGTATTATACCCAAGCCTAGTGTGTATTACAACTTCAACACTCCCCTTTGGCTTATATTACCAT
GTGCATAGCTAAAGTCTTCTATTTTTAGAACACCTTCTGTCTGTTCTTTCCCCATCAACTCCTTCCTCATCCTTCTTGGTGTTCTGTCAT
GGGCCATGGGCTTGCTATGGCCAGCCTTACTGAGGCCAAGCAGCTTATGGGATGTTCTTTATTGTGTGTGATGGTATTGGTTTGTTTGGT
AGATAAGTGGGAGGAAAAGTACTGTTGCTACACTATTATAGGCATGTTTGATACTAGCAGCTAACACTGGTCACTCCAAAGCACTGTTTC
TATAGGAACATTGAAGCTATTAAGATGTTTTGATTATCCTAATTACATAATGACCGATTTGAGATAGAGGCCTTTAAATACATTCCATGC
CCTCCCCAGAAAATAGTCTGTGGGAGTCAGTTGCCTTGGTGCCAGGTATGTGTTCTGATGTAGGTCATGAGTCTTTCTACTTAATGGGAA
GGGAAGAACATTTGTTTCCAGGATGACTTTCTGGCCAGAATACCGGAAAGCTTTTAGGAAGCTTCGTTCACATGCTATTTAAATGCACAA
AATAGACAGTAAGGATTTATCTGTTCAGTTTTTCTTCCCAGTGAATTAATTTCAGCTTATATGGGTGTCTTCATTTGAACATGAGGAATA
TTAGGTTATATTTTCAGCAGTGGTTTTTTCCTTTGCCCTTTAAGGAGTGGGGATAATGTCCACGGTGGCCCAGCCTCTTGCTGATGGCAC
CTTCCCTGCATTGCTGCCTCCCGATGATGTGGTTCTTTTCTTGTGCCTGTGGCTTTGGGAATGTAACATCTCTTTCCTCCTTTCCTTCCC
TTTTCCTCTTCACCTGAGGTCCTAAATACTCTCTGTAATTACTGTGTTCTTCACGGTAATTAGACATCATTCAGTGAATAAATTACTGTA
GTCAAAGACAGTATGGGCTGGCAGTTTGTGTAATTGCAAGTTCATAAAGAGAATTGAGGGTCCAGTTGGGAGAACTATTAGTCAGTTCTT
TTATATGCTGATAAATGATCCCTCGAGTTCAGTTAGTATTCTGTCCAGAGTGTTTAGCTCACTTTCTTAGCAGTGTGTAAGCTTTCTCCA
TGTCAGAAGCAAGCCTGCTCTTTGATAAATCTGTCTTCCTGAAAATCTAAATCATGCTTTTGTCTTTAGATCTACACAGAAATGACCCTC
CTTGGATCAGTTTTCTTTCCAGTCTAATCATCTTTGGAACTAAAACTTGTTCTAACTCGTCTCTTGGCATTCAGCTACTCCTAGATCTTT
TGGTTTTATCCCCTGGCCTCAGAGCCATTTATATTCCCAGAGTAGGCAGTACAGGATCTCGTGTTGATTTGCTGTGGTTACCCAGTGTCT
TCTCTACATGGCATAAAGCGGCAAAGCCCACCATTAGGTGAGGCGGTCCCGAGTTGAGGTAGAGTGGGGCAGAGGAAGATGGCAGTGAAT
ATCAAACAGTAGACCGCCATCAACTTCTAACAGCCAGTACACACACTGTTTCATTTTGAGGTAACGTTCAGTTTTGCATTTTGTTTAAAT
ATTGAAGGCCTAGACAAAGAACTAGAAAAAAAAAAGCAGTTTCCAGGCCCATCCATATTGTAATTTTTCTTTATCTGCAGATATTGCCTG
TAGTCTAAAGATCTCTTTGGAAGACAAAGCATTGGCTATATATCTTTTGCCTTTTCCATGCATCTAAATCTTCTCTGGAGATTATCTCCC
TACTGTGTAGGTTAAGGGCAGTCTCGACTTTTCCTTTTTTGAGTCCTGTGTGGCTCTTTGAATCAGCGTGAAACTGAGGCTCCAGCTCCC
TGTGTTGTGTGTGTGTGCCATCCATGGGCTTGGGTGTCAGTTTGTCACAGGTATCTGCCAGCATTCAAGGTTTTGGATCATTTCATGAGG
ATCTTTCCTTTGACTGGGTGCTGTGAGGACACACCTGGGTCTGTGCCTGAGATTGCCAGGCAAGATTAAGGAAAGTTTTCATGTGGCTTT
TGTTTTGAGGTTATTCTCAAAACCTTAATTTCTTATATTTTCTGTTGACTAAGGCACCAGTAACCCATTCTTCACCCTCCATTTGTATGG
CAATTTAAAAGTCTTTGGCTTTGCTCTGAATTTAATTAAAACTGCCTTTTATGAACAGACTTCGAGTTTTGCCATTTTGGGCAAGCCCTT
CCGCTTGTCCCTTCCTAGTGGCTAATAAAGTAAAAAAACCCACACTACTTTGTTCTCTTTTTCTCATATTCATTGGGCTGTTGTATTCAG
CCAGTCTCATGCTTTCCCTGGGTCTTCACGGATTGCTTTCCAAGCTGCCTTGTTGCGGGGTTGCTGCAGAGCAGCAACTGGACCTTTCCA
GCTGTCGCCATGTTCCTTCCACTAAAGTAGAGGGTTCTTAAAATGGAAAAACCTGTGGGCTCTTCATATACCTCCCTTTAGTTAAGTAAT
AGACCAGGCAGCTTCTCATCTCAGCATTTACCTGTTAATATTTTTGTGAATAGTGCTCTCTACCTGTGGGTGGCCGTTCTCTTCCACTTG
CTCGTCTCCCCCCAGCCCCATTCTGCATAATCTACCATTCTTCTCCTCTCTTTCTCTTCTTATACAGACCCTCATTACTGGGGCCCAAGA
TGTGGGATACTACTGTTAGTATTATTTAACTATTTTGTAGATTTAAAAGATTTCTGGTTAAGGGAGGTGGGGGTCACTGTTCATCACTCT
TAAAATATGTGTTTTCTCTATAGAAAAGTAAAATGTGTTTATGGTCCCAAACAGTCAACTCACAAATTTTTATAACAAAATTTCCTTGTA
AAAACTAGGGACCATCTATATATTCCCTTTAAGATCTAGTTCTTTTTGTAGGTGTTCAGCAATGGTGATAAAGCAGAATATTCTCCTACC
TCACGTCATTAAAGTCAGAAGATTATAGACCTTCTCAAACTATAAGTCCCTCTTCTTGCCGTTGGCCTTTCTGACTCTGGAATGACCACT
GTTCATTGAAAAATAGTTTTCTGACTATTGGTCTGGCTCTAACAGTTTGTTTGTTCATCCAGCAAATGTTTATGAGTGATGACCATGTGC
CAGAAATGTCAGGTATGTGTCCTTCCCTTGGCGCCACATAGTAGTTTACTAATGTTTGGGGGATTGTACTTGGACTGTCATAGCCTCTGC
GTTTGACCTTAAAATAGCTCTTCCCAGTAAGATTGTGCAATTTTTATTCACAGCTCTTCCATGTAGACTTACCTTTCCTCATAGAGCTAT
CCTGGTTAATAACAGGCCAAGATTCTCCCATTATCCCCTGTTGTCTCCTGTAGCTTTGATAATGCCTGGGAGATTCCTTGGTGTAAGTGT
CATGGATACCGACTGTTTTTATGTTGGAATTTGTTCCAACATAATTAGAATCTGTTTGGTGAGTTGAAAGGTAAGTTGGCTCAGAGTTGC
ACAGTAGGGCATTAAATGTTTAAGCAAAGCATCTGCCCACACTCCCCTTTCCAATCTAGTGCCTTCCTTGAACTTTTTCCTGAGCTGCTA
CGTCCCTAATCCCCCTTGTTGGGAGGATTTTCGTATCACCCTTATGGGACCTGTCACCATGTCCTGTACTATTTGGAATTGGTTTTCCAG
TCTTTCAACAACCGTTGTGGCTAACTATGTTTTAGAAGGGCTGGAGGTGTGGGCCCTGTCTTCGGGTCTCAGGACCCAAAGATCCTTTAG
TCAGTTGTTGGGTCTTCCAAGAGCCAGACATTAATACAGATTGAACTCCATCAGTCCCCTAATTGTCAGCCTTTACCTCCCTCCCAGAGC
AAGGAGTTTAGGGATTCTAAAGCTTAGTGTCCACACATCATTCTACCAGACCTTAGAGCTTTAGAAGCTCAATCTAAAATACTGTAACTC
AGCATAAACTATTACTATCACTCCTTTGAACTCAGTCTCCATGAGCAGTGTTTTGTTGGAAATACATAGAACGGCTTAATGCCTAGAGGG
TGGTGGATAGTGAAGGACGGTCAAGGTTATATTTTTGACTGCTTAGGGATTCTTTGGATCCAAGAAACAGAAATGTTCAAGCGGAATAAA
GGAGGGAGTGGAGTTGTGGTAAGGATGCAGGGTATTTCGCAGAACCCAGGACGGGAAGTGCCTTTGGTTCTTGGGTGGAGCTGGAACTGC
AGAGCTTTGCACCTAGTCCTTTCTCCCGCTTCACAGTCTGCTTATGGTATATGTGGCCCCCAAATAGGCACTCTAGTCCTCAAGTCTACA
CCACCTTCCAACTCTGGGGATCACCATGAACAAATTCTCAATTTCCCATACTTAATTTTTTTTTTTTTTGAGATGGAGTCTCGCTGTGTC
GCCCAGGCTGGAGTGCAGTGGTGCAGTCTCAACTCACCACAACCTCTGCCTCCCAGGTTCAAGCAGTTCTCTGCCTCAACCTCCCGAGTA
GCTGGGATTACAGGCGCCTGCCACCATGCCCAGCTAATGTTCATATTTTTAGTAGAGACAGGGTTTCACCGTCTTGGCTAGGCTGGTCTT
GAACTCCTGACCCTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTAAGATTACAGGCGTGAGCCACCGCGCCCGGCCCATACTTCGTA
TTCTTAAAAAAAACTACACTCAGCCCAGCACATTGATCAAGTATCTATCTCTGAGCAGTTGGCCTTGCCAGGGAGAGCAGAGATGTGGCA
GGCTCCTTCAGCTGGAGACAGGGAGCTTCTCAGAGAAGTGAGCAGAGACTCCACAGACACCCTAAAAAGGCTTCTACTCAAGAAGTAAAG
CCACTACTCCTGCCTTTTTGCTTAGTGGACAGGAAGGCACAGGAGTTTGTCTGGGACATCATAGAAATTCTTAGGTTTAACTTAATTCTG
GTCATTGTCTTCTTTATTTCCTGTTTTTCTTCCCTTTGTCAGTCTTCGCATCCAAGATTTCTTCCCTCCCTCTTGTGGGCCAGCCTGTCC
TGTTCCAGAGCTAGCCTGTTCCTGGGTAGCCTTCCTTAGCCTCCATTCAGCCTCAGGTCTTTTGCCTTCTTCCGTGTTTATTTAGAGAGC
AGAATCTAATAACGGGTTCCACTGTAGCCACTATCCATGGACTTCTGGGTCCTCTTCAGGTTTGAGTGCTTGAAAATGTTCATTCTCTGG
GCTTGTGGCCTGTCTCCTCCACTCTCCTCCTCACCCTCTCGCTCCTTCCTGTGTGAGGGCCGCTCTGCAGTAATGTTCTCAGGCAAGCCT
TCCTAGGCACCTCAGAAACTACTTTGCCAGAGCCAGTAAGAATATATAATATTGGAGCAGTTGCCAGGATAGAAATTAAATATAGATTCC
AGTTTAGGATAGAGTTTTTACCGAGAGCTCTTTAGACAGTATACCTGTGTCTTCTCTGGCAATTGCTTTCATTTTAGTCCTATATAAAAG
CTTTCCTTTTCTGTTTTTTTTTAAAACTATGCTTTTGCTTGCCTAAATCTTTTGATCTTATATTTCTCTCATCTCAGAGCCTGTCCTGAG
TTGTAAGGTATTTCATACTGCCTTACTTAAAAGTTTTTTAAACTACTAGAGTCATTTGATACACACAGAAGTTACCTAATAATCCAAAGA
TGTCCATCAAGGGAGGAAGGGTGGGTCATCAGACTTTGCCTTTGATGTTGTAGACTAGGCTCCTGAGTTAAGCAGCAGAGGGACAGCAGT
GCCATGTGCCTTCACTGTGTCCCAGGAAATCTGGGTTGGTTCCAGTGGGAAATACCAGTATTTCTTGGTTCTGGAAAGTAGCAAAAGAGT
AGGAGATGGGGAAATAGGGATGGGGAGAGCAAGCCCCGCATGTCCATGGCGAGTCAGGTGGGGAGCACGGGTGGAAGGGCCGGCTGTTGA
CAGACAGACTAAGCTGTGTGGTGCTCTTGCCGCCCCTTCCTGGGTACAGAGCTTGAGAAAAATGCAGCCGACCACTCCCTGTGTTTGTAC
AGAGCAAAGCCCAAAAGCCAACCTCAGATCTCCTGATTTGGCAGCTGAAGAAATCAGCAGAGTCCTGATTGCCTGATTCAGTCCCAAAAA
TGAATGTCAGGCCCCGCCCCCTCCCCACCAACATTGCCTCTCCTACATTCTCCTTCTGCCCCTAAATCAGACAGGAGGCCAGAGAGGAGT
ATTGCTCAATGCGTGCTATGTGCAACTCCTCAGGCCTTGTGCCACCTCCATGCTGAGCCCTGAAGCAGGGTGTCCTGGGTGCCTGTGTGT
CAGCTCCCTCCTCTCTACCTACCTCTGACCTTCTTGTGGGTGAGGGTGGCCATGCTTATGGCCATCTTAAAACTGGAGAGGCAGAGAACT
ACTTATGAGTCTGTAGACCACGTGTTGTCTTCCATGGCCTGTTTCTCCTGCTGTCTGGGTGAGTGAGCCTGCAACGCAATGCCCATGAGA
GTAAATGCCTCCTGACCTACCCTGCTCAGCACTGTTCTAGTGTCTTGGCCTTGAAAGAAAAGCCTGACTTCCTGCTGACACATGTGGTAG
GGGCATGGCAGCTATGAGGCACCTCCTACGTCTGTTTTCTGGCTGTGGTGACTTGGGATTTTTAACCTTATATATCTTTTTCCTTTACTC
AAAACAAAACAATTTTTAGCACACTGAAAAAAAAAAAAAGCCAAATGTTTTGTGCCTTTCTAAGGCAGCACTGTATCCCAGGCTGCATTT
TAGGACTTAATATGGAAATACCAGAGTCTGAGCTCCTCTACCTTGAGTTTCATTAGTCCTTAGTGTCTAGGAGACAGGAAAGAATGCTCT
CTGTGACTGGAGAGGTGACATGCAGGTGCAGTGTGTCTGGAGTCCCTTTCCCCTGCTGTGAGACTTCAGTGGAGGAGAGAAGCATTGTAC
CCTGGGATCATTTGGTTGGTTCCAATCACAAGCTTAGTTATCAGGTTGCATGCCTTGTCTCCTGCAAAAGACAGAATGTTTCACAATTCC
CAGGTAAACTCTGGACCATTCCAAGTGTCCTAGCCTTCTGATGACATTAATTACCTAGTTGTGTCGAGGAGTATAGGATGGACTCTCCTG
AGAAGGGGAGGTTGGTGGCTTTGTCTTTTCTTTTTGCTGGATCCTGAACTGGTCTAGACCTCCTGCCCCCACCCCCCAGCCCCCATCAGA
TGTGGCTGGCCTTTCATTTGAAGGCTTCAGACTTAAAGCATTAAGCAGCTAGTGCCCTCTGCAGGGCCTGGTTTCCCCAGGGAAGGGCAG
CAAGGAACATGGGACCAGAAGCCTGTCCTCAGTAATGTGACTATAGTGAGCTTTAGCAAAAGTTTTTCTATATAATGACATCTTACTTAT
CTTTTACCCTTTCCTCAGTTTTCCCCTGCCTTTAACTAATAAAGAATTGGGAGACAGAAATTTTAAAGTCCTCCTTATTCAAGATTTTGA
AATTCTTAGCCTGGGAGTGCTGGAGAGAACCTGATGCTTTCTCCAGAATGAAGAGTCCCAATTTGTATATCAGTGTTAAGAAGAAAACAA
AACAAACACATAGGTGAGATTTTCGTGGACTATTTTAAAAATGTGTCATTAATATAAAAAATTTATATTAGCAGTATTTAATCATTCTCA
CCTGTAAAGAATAAGAAAAACAGAAGGTAAATATTCTTACAGAGAATAGCAGAGCTTTAAGATTCATTTTCATTTTAAGTCCATTTTATT
TTGCCAGTGTATTAATGTTTAGAAGTCTGTTTTACTAATGTTATTTATTAATTTTTTTTCATTTCCATACACAGTTAGTTAACTAAAGAG

>43149_43149_4_KMT2A-CBL_KMT2A_chr11_118353213_ENST00000354520_CBL_chr11_119155677_ENST00000264033_length(amino acids)=1791AA_BP=7
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVG
AESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDT
SMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMY
NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPK

--------------------------------------------------------------
>43149_43149_5_KMT2A-CBL_KMT2A_chr11_118353213_ENST00000389506_CBL_chr11_119155677_ENST00000264033_length(transcript)=13744nt_BP=4086nt
ATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGGGGCGCCGGGGCCTAGGGGGCGCC
CCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGGCGCCCCCCTCCCCCCCGGCTGTG
GCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAGCAGCCTCCTCGTCGTCCGCCTCG
TCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCGACGCGGCGCTGCAGGTCTCGGCC
GCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCGGAGAGGATGAGCAATTCTTAGGT
TTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTCGAAAACCTCGTGGGAGACCTAGA
AGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAGAGACCAAATCTGGAGATAAGATC
AAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAATCAAAATAACACATGGAAAGGAC
ATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTACGTTTCAGCAAGCCACAAAGATT
AAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAGGAAGGAAGGGGGTACAAATTGTA
CGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTGAACTGGAAAAGCCCCAGAAAGTC
CGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTCGAAGGATTAAGCCAGTTAGGATT
ATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGGCTCAAAAGAAAATTGAAAAAGAA
GCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTGTTGTCAGTGCTATCTCCTCGCGG
ATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGATTAGAGTCTACACCGAATAGTAGA
TTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGTCTTCAGACTCCTCTCGATCTAGT
AGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGCGGAGCGATACCCCTGAAGTTCAT
CCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAGTGTCGGAGAGAAGTTTTGGATCT
AGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTCCACCTCTGCTGACTCCACCGCCA
CCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAGCATCACCATTTTTGCCTGCTTCC
ACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAAAGCATTCTAGGTCAGAGCCACAA
TACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGACCCCCTCCACTAACTCCCGAGGAC
GTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCCATTCTGGAACAAGGTTTGATATG
CACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTGAGTCTGTAACCTTGCCTAGTAAT
CGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTCCTATTCGATCTGAACCAAGATCT
CCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCCCGTCTTCTGTCTCTTCCTCGTTA
AGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCCTGACTCAGTCTGGGGAATCTGCA
GAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTACTCCTCTCTTCCCTTGGTTTACC
CCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAGATGCTGACAAGAGCGTGGAGAAG
GACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAAGGAAAAAGGGATCAGAAATTCAG
AGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCACTTCATCTTCTGCCAAAAAAGCA
ACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATACAACAGCTGTCAAAACCAAAATA
CTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCCTGGAGAAGGAGAAAACCCTCTGC
CTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGGCAGACAAGCTTCCAATGACTGAC
AAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTCTTAAACAAACCGACCAGCCCAAA
GCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCAGAAGAGCAGCTGTTGCCCTTGGC
CGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAAAGATTTTGTCTTCCATGGGGAAT
GATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTAAACCTGTCACTAGAAACAAGGCA
CCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGGTGCCTGAGGACTGTGGTGTTTGT
ACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAAAATGTCAGAATCTACAATGGATG
CCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCAGTGAAAAGAAAGACAGCAAAGAG
AGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTGCCCCAAAGAAAAGCAGTAGTGAG
CCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAATCCAAACAGGCCACCACTCCAGCT
TCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAGGACCGCCAAGAAAAGAAGTTCCC
AAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCAAACAGAAAAAAGTGGCTCCCCGC
CCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGTGGAACGGCCGCCTTCTCCATTCTCCATGGCCCCACAAGCTTCCCTTCCCCCG
GTGCCACCACGACTTGACCTTCTGCCGCAGCGAGTATGTGTTCCCTCAAGTGCTTCTGCTCTTGGAACTGCTTCTAAGGCTGCTTCTGGC
TCCCTTCATAAAGACAAACCATTGCCAGTACCTCCCACACTTCGAGATCTTCCACCACCACCGCCTCCAGACCGGCCATATTCTGTTGGA
GCAGAATCCCGACCTCAAAGACGCCCCTTGCCTTGTACACCAGGCGACTGTCCCTCCAGAGACAAACTGCCCCCTGTCCCCTCTAGCCGC
CTTGGAGACTCATGGCTGCCCCGGCCAATCCCCAAAGTACCAGTATCTGCCCCAAGTTCCAGTGATCCCTGGACAGGAAGAGAATTAACC
AACCGGCACTCACTTCCATTTTCATTGCCCTCACAAATGGAGCCCAGACCAGATGTGCCTAGGCTCGGAAGCACGTTCAGTCTGGATACC
TCCATGAGTATGAATAGCAGCCCATTAGTAGGTCCAGAGTGTGACCACCCCAAAATCAAACCTTCCTCATCTGCCAATGCCATTTATTCT
CTGGCTGCCAGACCTCTTCCTGTGCCAAAACTGCCACCTGGGGAGCAATGTGAGGGTGAAGAGGACACAGAGTACATGACTCCCTCTTCC
AGGCCTCTACGGCCTTTGGATACATCCCAGAGTTCACGAGCATGTGATTGCGACCAGCAGATTGATAGCTGTACGTATGAAGCAATGTAT
AATATTCAGTCCCAGGCGCCATCTATCACCGAGAGCAGCACCTTTGGTGAAGGGAATTTGGCCGCAGCCCATGCCAACACTGGTCCCGAG
GAGTCAGAAAATGAGGATGATGGGTATGATGTCCCAAAGCCACCTGTGCCGGCCGTGCTGGCCCGCCGAACTCTCTCAGATATCTCTAAT
GCCAGCTCCTCCTTTGGCTGGTTGTCTCTGGATGGTGATCCTACAACAAATGTCACTGAAGGTTCCCAAGTTCCCGAGAGGCCTCCAAAA
CCATTCCCGCGGAGAATCAACTCTGAACGGAAAGCTGGCAGCTGTCAGCAAGGTAGTGGTCCTGCCGCCTCTGCTGCCACCGCCTCACCT
CAGCTCTCCAGTGAGATCGAGAACCTCATGAGTCAGGGGTACTCCTACCAGGACATCCAGAAAGCTTTGGTCATTGCCCAGAACAACATC
GAGATGGCCAAAAACATCCTCCGGGAATTTGTTTCCATTTCTTCTCCTGCCCATGTAGCTACCTAGCACACCATCTCCCTGCTGCAGGTT
TAGAGGACCAGTGAGTTGGGAGTTATTACTCAAGTGGCACCTAGAAGGGCAGGAGTTCCTTTGGTGACTTCACAGTGAAGTCTTGCCCTC
TCTGTGGGATATCACATCAGTGGTTCCAAGATTTCAAAGTGGTGAAATGAAAATGGAGCAGCTAGTATGTTTTATTATTTTATGGGTCTT
GAGTGCATTTGAAGGTGTCCTTCAGTTCCCACGTAGAGAGAGTGTGGATTATATTACATGATAACCTACCTGGGGAACAGTCCAGAAAGC
TATAGAACAAGTATTTTGCTGGAAATCCTAATTGAGGACTTAAGACTTCCTGGGTTAAGGATGTGGCCGTGTGTGTGTGTGTCTGCCTGT
GGTTGTATGTGTCCTTGTGATTATAAGATTAACCTGCTGTGTGTGTTAATTCCAGGCAGGGAATTAGCACAAAAGGTTTAGGAAGGAATC
TTTTTTTAAAGACTTCCATCTACTGTGGTATTATACCCAAGCCTAGTGTGTATTACAACTTCAACACTCCCCTTTGGCTTATATTACCAT
GTGCATAGCTAAAGTCTTCTATTTTTAGAACACCTTCTGTCTGTTCTTTCCCCATCAACTCCTTCCTCATCCTTCTTGGTGTTCTGTCAT
GGGCCATGGGCTTGCTATGGCCAGCCTTACTGAGGCCAAGCAGCTTATGGGATGTTCTTTATTGTGTGTGATGGTATTGGTTTGTTTGGT
AGATAAGTGGGAGGAAAAGTACTGTTGCTACACTATTATAGGCATGTTTGATACTAGCAGCTAACACTGGTCACTCCAAAGCACTGTTTC
TATAGGAACATTGAAGCTATTAAGATGTTTTGATTATCCTAATTACATAATGACCGATTTGAGATAGAGGCCTTTAAATACATTCCATGC
CCTCCCCAGAAAATAGTCTGTGGGAGTCAGTTGCCTTGGTGCCAGGTATGTGTTCTGATGTAGGTCATGAGTCTTTCTACTTAATGGGAA
GGGAAGAACATTTGTTTCCAGGATGACTTTCTGGCCAGAATACCGGAAAGCTTTTAGGAAGCTTCGTTCACATGCTATTTAAATGCACAA
AATAGACAGTAAGGATTTATCTGTTCAGTTTTTCTTCCCAGTGAATTAATTTCAGCTTATATGGGTGTCTTCATTTGAACATGAGGAATA
TTAGGTTATATTTTCAGCAGTGGTTTTTTCCTTTGCCCTTTAAGGAGTGGGGATAATGTCCACGGTGGCCCAGCCTCTTGCTGATGGCAC
CTTCCCTGCATTGCTGCCTCCCGATGATGTGGTTCTTTTCTTGTGCCTGTGGCTTTGGGAATGTAACATCTCTTTCCTCCTTTCCTTCCC
TTTTCCTCTTCACCTGAGGTCCTAAATACTCTCTGTAATTACTGTGTTCTTCACGGTAATTAGACATCATTCAGTGAATAAATTACTGTA
GTCAAAGACAGTATGGGCTGGCAGTTTGTGTAATTGCAAGTTCATAAAGAGAATTGAGGGTCCAGTTGGGAGAACTATTAGTCAGTTCTT
TTATATGCTGATAAATGATCCCTCGAGTTCAGTTAGTATTCTGTCCAGAGTGTTTAGCTCACTTTCTTAGCAGTGTGTAAGCTTTCTCCA
TGTCAGAAGCAAGCCTGCTCTTTGATAAATCTGTCTTCCTGAAAATCTAAATCATGCTTTTGTCTTTAGATCTACACAGAAATGACCCTC
CTTGGATCAGTTTTCTTTCCAGTCTAATCATCTTTGGAACTAAAACTTGTTCTAACTCGTCTCTTGGCATTCAGCTACTCCTAGATCTTT
TGGTTTTATCCCCTGGCCTCAGAGCCATTTATATTCCCAGAGTAGGCAGTACAGGATCTCGTGTTGATTTGCTGTGGTTACCCAGTGTCT
TCTCTACATGGCATAAAGCGGCAAAGCCCACCATTAGGTGAGGCGGTCCCGAGTTGAGGTAGAGTGGGGCAGAGGAAGATGGCAGTGAAT
ATCAAACAGTAGACCGCCATCAACTTCTAACAGCCAGTACACACACTGTTTCATTTTGAGGTAACGTTCAGTTTTGCATTTTGTTTAAAT
ATTGAAGGCCTAGACAAAGAACTAGAAAAAAAAAAGCAGTTTCCAGGCCCATCCATATTGTAATTTTTCTTTATCTGCAGATATTGCCTG
TAGTCTAAAGATCTCTTTGGAAGACAAAGCATTGGCTATATATCTTTTGCCTTTTCCATGCATCTAAATCTTCTCTGGAGATTATCTCCC
TACTGTGTAGGTTAAGGGCAGTCTCGACTTTTCCTTTTTTGAGTCCTGTGTGGCTCTTTGAATCAGCGTGAAACTGAGGCTCCAGCTCCC
TGTGTTGTGTGTGTGTGCCATCCATGGGCTTGGGTGTCAGTTTGTCACAGGTATCTGCCAGCATTCAAGGTTTTGGATCATTTCATGAGG
ATCTTTCCTTTGACTGGGTGCTGTGAGGACACACCTGGGTCTGTGCCTGAGATTGCCAGGCAAGATTAAGGAAAGTTTTCATGTGGCTTT
TGTTTTGAGGTTATTCTCAAAACCTTAATTTCTTATATTTTCTGTTGACTAAGGCACCAGTAACCCATTCTTCACCCTCCATTTGTATGG
CAATTTAAAAGTCTTTGGCTTTGCTCTGAATTTAATTAAAACTGCCTTTTATGAACAGACTTCGAGTTTTGCCATTTTGGGCAAGCCCTT
CCGCTTGTCCCTTCCTAGTGGCTAATAAAGTAAAAAAACCCACACTACTTTGTTCTCTTTTTCTCATATTCATTGGGCTGTTGTATTCAG
CCAGTCTCATGCTTTCCCTGGGTCTTCACGGATTGCTTTCCAAGCTGCCTTGTTGCGGGGTTGCTGCAGAGCAGCAACTGGACCTTTCCA
GCTGTCGCCATGTTCCTTCCACTAAAGTAGAGGGTTCTTAAAATGGAAAAACCTGTGGGCTCTTCATATACCTCCCTTTAGTTAAGTAAT
AGACCAGGCAGCTTCTCATCTCAGCATTTACCTGTTAATATTTTTGTGAATAGTGCTCTCTACCTGTGGGTGGCCGTTCTCTTCCACTTG
CTCGTCTCCCCCCAGCCCCATTCTGCATAATCTACCATTCTTCTCCTCTCTTTCTCTTCTTATACAGACCCTCATTACTGGGGCCCAAGA
TGTGGGATACTACTGTTAGTATTATTTAACTATTTTGTAGATTTAAAAGATTTCTGGTTAAGGGAGGTGGGGGTCACTGTTCATCACTCT
TAAAATATGTGTTTTCTCTATAGAAAAGTAAAATGTGTTTATGGTCCCAAACAGTCAACTCACAAATTTTTATAACAAAATTTCCTTGTA
AAAACTAGGGACCATCTATATATTCCCTTTAAGATCTAGTTCTTTTTGTAGGTGTTCAGCAATGGTGATAAAGCAGAATATTCTCCTACC
TCACGTCATTAAAGTCAGAAGATTATAGACCTTCTCAAACTATAAGTCCCTCTTCTTGCCGTTGGCCTTTCTGACTCTGGAATGACCACT
GTTCATTGAAAAATAGTTTTCTGACTATTGGTCTGGCTCTAACAGTTTGTTTGTTCATCCAGCAAATGTTTATGAGTGATGACCATGTGC
CAGAAATGTCAGGTATGTGTCCTTCCCTTGGCGCCACATAGTAGTTTACTAATGTTTGGGGGATTGTACTTGGACTGTCATAGCCTCTGC
GTTTGACCTTAAAATAGCTCTTCCCAGTAAGATTGTGCAATTTTTATTCACAGCTCTTCCATGTAGACTTACCTTTCCTCATAGAGCTAT
CCTGGTTAATAACAGGCCAAGATTCTCCCATTATCCCCTGTTGTCTCCTGTAGCTTTGATAATGCCTGGGAGATTCCTTGGTGTAAGTGT
CATGGATACCGACTGTTTTTATGTTGGAATTTGTTCCAACATAATTAGAATCTGTTTGGTGAGTTGAAAGGTAAGTTGGCTCAGAGTTGC
ACAGTAGGGCATTAAATGTTTAAGCAAAGCATCTGCCCACACTCCCCTTTCCAATCTAGTGCCTTCCTTGAACTTTTTCCTGAGCTGCTA
CGTCCCTAATCCCCCTTGTTGGGAGGATTTTCGTATCACCCTTATGGGACCTGTCACCATGTCCTGTACTATTTGGAATTGGTTTTCCAG
TCTTTCAACAACCGTTGTGGCTAACTATGTTTTAGAAGGGCTGGAGGTGTGGGCCCTGTCTTCGGGTCTCAGGACCCAAAGATCCTTTAG
TCAGTTGTTGGGTCTTCCAAGAGCCAGACATTAATACAGATTGAACTCCATCAGTCCCCTAATTGTCAGCCTTTACCTCCCTCCCAGAGC
AAGGAGTTTAGGGATTCTAAAGCTTAGTGTCCACACATCATTCTACCAGACCTTAGAGCTTTAGAAGCTCAATCTAAAATACTGTAACTC
AGCATAAACTATTACTATCACTCCTTTGAACTCAGTCTCCATGAGCAGTGTTTTGTTGGAAATACATAGAACGGCTTAATGCCTAGAGGG
TGGTGGATAGTGAAGGACGGTCAAGGTTATATTTTTGACTGCTTAGGGATTCTTTGGATCCAAGAAACAGAAATGTTCAAGCGGAATAAA
GGAGGGAGTGGAGTTGTGGTAAGGATGCAGGGTATTTCGCAGAACCCAGGACGGGAAGTGCCTTTGGTTCTTGGGTGGAGCTGGAACTGC
AGAGCTTTGCACCTAGTCCTTTCTCCCGCTTCACAGTCTGCTTATGGTATATGTGGCCCCCAAATAGGCACTCTAGTCCTCAAGTCTACA
CCACCTTCCAACTCTGGGGATCACCATGAACAAATTCTCAATTTCCCATACTTAATTTTTTTTTTTTTTGAGATGGAGTCTCGCTGTGTC
GCCCAGGCTGGAGTGCAGTGGTGCAGTCTCAACTCACCACAACCTCTGCCTCCCAGGTTCAAGCAGTTCTCTGCCTCAACCTCCCGAGTA
GCTGGGATTACAGGCGCCTGCCACCATGCCCAGCTAATGTTCATATTTTTAGTAGAGACAGGGTTTCACCGTCTTGGCTAGGCTGGTCTT
GAACTCCTGACCCTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTAAGATTACAGGCGTGAGCCACCGCGCCCGGCCCATACTTCGTA
TTCTTAAAAAAAACTACACTCAGCCCAGCACATTGATCAAGTATCTATCTCTGAGCAGTTGGCCTTGCCAGGGAGAGCAGAGATGTGGCA
GGCTCCTTCAGCTGGAGACAGGGAGCTTCTCAGAGAAGTGAGCAGAGACTCCACAGACACCCTAAAAAGGCTTCTACTCAAGAAGTAAAG
CCACTACTCCTGCCTTTTTGCTTAGTGGACAGGAAGGCACAGGAGTTTGTCTGGGACATCATAGAAATTCTTAGGTTTAACTTAATTCTG
GTCATTGTCTTCTTTATTTCCTGTTTTTCTTCCCTTTGTCAGTCTTCGCATCCAAGATTTCTTCCCTCCCTCTTGTGGGCCAGCCTGTCC
TGTTCCAGAGCTAGCCTGTTCCTGGGTAGCCTTCCTTAGCCTCCATTCAGCCTCAGGTCTTTTGCCTTCTTCCGTGTTTATTTAGAGAGC
AGAATCTAATAACGGGTTCCACTGTAGCCACTATCCATGGACTTCTGGGTCCTCTTCAGGTTTGAGTGCTTGAAAATGTTCATTCTCTGG
GCTTGTGGCCTGTCTCCTCCACTCTCCTCCTCACCCTCTCGCTCCTTCCTGTGTGAGGGCCGCTCTGCAGTAATGTTCTCAGGCAAGCCT
TCCTAGGCACCTCAGAAACTACTTTGCCAGAGCCAGTAAGAATATATAATATTGGAGCAGTTGCCAGGATAGAAATTAAATATAGATTCC
AGTTTAGGATAGAGTTTTTACCGAGAGCTCTTTAGACAGTATACCTGTGTCTTCTCTGGCAATTGCTTTCATTTTAGTCCTATATAAAAG
CTTTCCTTTTCTGTTTTTTTTTAAAACTATGCTTTTGCTTGCCTAAATCTTTTGATCTTATATTTCTCTCATCTCAGAGCCTGTCCTGAG
TTGTAAGGTATTTCATACTGCCTTACTTAAAAGTTTTTTAAACTACTAGAGTCATTTGATACACACAGAAGTTACCTAATAATCCAAAGA
TGTCCATCAAGGGAGGAAGGGTGGGTCATCAGACTTTGCCTTTGATGTTGTAGACTAGGCTCCTGAGTTAAGCAGCAGAGGGACAGCAGT
GCCATGTGCCTTCACTGTGTCCCAGGAAATCTGGGTTGGTTCCAGTGGGAAATACCAGTATTTCTTGGTTCTGGAAAGTAGCAAAAGAGT
AGGAGATGGGGAAATAGGGATGGGGAGAGCAAGCCCCGCATGTCCATGGCGAGTCAGGTGGGGAGCACGGGTGGAAGGGCCGGCTGTTGA
CAGACAGACTAAGCTGTGTGGTGCTCTTGCCGCCCCTTCCTGGGTACAGAGCTTGAGAAAAATGCAGCCGACCACTCCCTGTGTTTGTAC
AGAGCAAAGCCCAAAAGCCAACCTCAGATCTCCTGATTTGGCAGCTGAAGAAATCAGCAGAGTCCTGATTGCCTGATTCAGTCCCAAAAA
TGAATGTCAGGCCCCGCCCCCTCCCCACCAACATTGCCTCTCCTACATTCTCCTTCTGCCCCTAAATCAGACAGGAGGCCAGAGAGGAGT
ATTGCTCAATGCGTGCTATGTGCAACTCCTCAGGCCTTGTGCCACCTCCATGCTGAGCCCTGAAGCAGGGTGTCCTGGGTGCCTGTGTGT
CAGCTCCCTCCTCTCTACCTACCTCTGACCTTCTTGTGGGTGAGGGTGGCCATGCTTATGGCCATCTTAAAACTGGAGAGGCAGAGAACT
ACTTATGAGTCTGTAGACCACGTGTTGTCTTCCATGGCCTGTTTCTCCTGCTGTCTGGGTGAGTGAGCCTGCAACGCAATGCCCATGAGA
GTAAATGCCTCCTGACCTACCCTGCTCAGCACTGTTCTAGTGTCTTGGCCTTGAAAGAAAAGCCTGACTTCCTGCTGACACATGTGGTAG
GGGCATGGCAGCTATGAGGCACCTCCTACGTCTGTTTTCTGGCTGTGGTGACTTGGGATTTTTAACCTTATATATCTTTTTCCTTTACTC
AAAACAAAACAATTTTTAGCACACTGAAAAAAAAAAAAAGCCAAATGTTTTGTGCCTTTCTAAGGCAGCACTGTATCCCAGGCTGCATTT
TAGGACTTAATATGGAAATACCAGAGTCTGAGCTCCTCTACCTTGAGTTTCATTAGTCCTTAGTGTCTAGGAGACAGGAAAGAATGCTCT
CTGTGACTGGAGAGGTGACATGCAGGTGCAGTGTGTCTGGAGTCCCTTTCCCCTGCTGTGAGACTTCAGTGGAGGAGAGAAGCATTGTAC
CCTGGGATCATTTGGTTGGTTCCAATCACAAGCTTAGTTATCAGGTTGCATGCCTTGTCTCCTGCAAAAGACAGAATGTTTCACAATTCC
CAGGTAAACTCTGGACCATTCCAAGTGTCCTAGCCTTCTGATGACATTAATTACCTAGTTGTGTCGAGGAGTATAGGATGGACTCTCCTG
AGAAGGGGAGGTTGGTGGCTTTGTCTTTTCTTTTTGCTGGATCCTGAACTGGTCTAGACCTCCTGCCCCCACCCCCCAGCCCCCATCAGA
TGTGGCTGGCCTTTCATTTGAAGGCTTCAGACTTAAAGCATTAAGCAGCTAGTGCCCTCTGCAGGGCCTGGTTTCCCCAGGGAAGGGCAG
CAAGGAACATGGGACCAGAAGCCTGTCCTCAGTAATGTGACTATAGTGAGCTTTAGCAAAAGTTTTTCTATATAATGACATCTTACTTAT
CTTTTACCCTTTCCTCAGTTTTCCCCTGCCTTTAACTAATAAAGAATTGGGAGACAGAAATTTTAAAGTCCTCCTTATTCAAGATTTTGA
AATTCTTAGCCTGGGAGTGCTGGAGAGAACCTGATGCTTTCTCCAGAATGAAGAGTCCCAATTTGTATATCAGTGTTAAGAAGAAAACAA
AACAAACACATAGGTGAGATTTTCGTGGACTATTTTAAAAATGTGTCATTAATATAAAAAATTTATATTAGCAGTATTTAATCATTCTCA
CCTGTAAAGAATAAGAAAAACAGAAGGTAAATATTCTTACAGAGAATAGCAGAGCTTTAAGATTCATTTTCATTTTAAGTCCATTTTATT
TTGCCAGTGTATTAATGTTTAGAAGTCTGTTTTACTAATGTTATTTATTAATTTTTTTTCATTTCCATACACAGTTAGTTAACTAAAGAG

>43149_43149_5_KMT2A-CBL_KMT2A_chr11_118353213_ENST00000389506_CBL_chr11_119155677_ENST00000264033_length(amino acids)=1791AA_BP=7
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVG
AESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDT
SMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMY
NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPK

--------------------------------------------------------------
>43149_43149_6_KMT2A-CBL_KMT2A_chr11_118353213_ENST00000534358_CBL_chr11_119155677_ENST00000264033_length(transcript)=13767nt_BP=4109nt
CTGCTTCACTTCACGGGGCGAACATGGCGCACAGCTGTCGGTGGCGCTTCCCCGCCCGACCCGGGACCACCGGGGGCGGCGGCGGCGGGG
GGCGCCGGGGCCTAGGGGGCGCCCCGCGGCAACGCGTCCCGGCCCTGCTGCTTCCCCCCGGGCCCCCGGTCGGCGGTGGCGGCCCCGGGG
CGCCCCCCTCCCCCCCGGCTGTGGCGGCCGCGGCGGCGGCGGCGGGAAGCAGCGGGGCTGGGGTTCCAGGGGGAGCGGCCGCCGCCTCAG
CAGCCTCCTCGTCGTCCGCCTCGTCTTCGTCTTCGTCATCGTCCTCAGCCTCTTCAGGGCCGGCCCTGCTCCGGGTGGGCCCGGGCTTCG
ACGCGGCGCTGCAGGTCTCGGCCGCCATCGGCACCAACCTGCGCCGGTTCCGGGCCGTGTTTGGGGAGAGCGGCGGGGGAGGCGGCAGCG
GAGAGGATGAGCAATTCTTAGGTTTTGGCTCAGATGAAGAAGTCAGAGTGCGAAGTCCCACAAGGTCTCCTTCAGTTAAAACTAGTCCTC
GAAAACCTCGTGGGAGACCTAGAAGTGGCTCTGACCGAAATTCAGCTATCCTCTCAGATCCATCTGTGTTTTCCCCTCTAAATAAATCAG
AGACCAAATCTGGAGATAAGATCAAGAAGAAAGATTCTAAAAGTATAGAAAAGAAGAGAGGAAGACCTCCCACCTTCCCTGGAGTAAAAA
TCAAAATAACACATGGAAAGGACATTTCAGAGTTACCAAAGGGAAACAAAGAAGATAGCCTGAAAAAAATTAAAAGGACACCTTCTGCTA
CGTTTCAGCAAGCCACAAAGATTAAAAAATTAAGAGCAGGTAAACTCTCTCCTCTCAAGTCTAAGTTTAAGACAGGGAAGCTTCAAATAG
GAAGGAAGGGGGTACAAATTGTACGACGGAGAGGAAGGCCTCCATCAACAGAAAGGATAAAGACCCCTTCGGGTCTCCTCATTAATTCTG
AACTGGAAAAGCCCCAGAAAGTCCGGAAAGACAAGGAAGGAACACCTCCACTTACAAAAGAAGATAAGACAGTTGTCAGACAAAGCCCTC
GAAGGATTAAGCCAGTTAGGATTATTCCTTCTTCAAAAAGGACAGATGCAACCATTGCTAAGCAACTCTTACAGAGGGCAAAAAAGGGGG
CTCAAAAGAAAATTGAAAAAGAAGCAGCTCAGCTGCAGGGAAGAAAGGTGAAGACACAGGTCAAAAATATTCGACAGTTCATCATGCCTG
TTGTCAGTGCTATCTCCTCGCGGATCATTAAGACCCCTCGGCGGTTTATAGAGGATGAGGATTATGACCCTCCAATTAAAATTGCCCGAT
TAGAGTCTACACCGAATAGTAGATTCAGTGCCCCGTCCTGTGGATCTTCTGAAAAATCAAGTGCAGCTTCTCAGCACTCCTCTCAAATGT
CTTCAGACTCCTCTCGATCTAGTAGCCCCAGTGTTGATACCTCCACAGACTCTCAGGCTTCTGAGGAGATTCAGGTACTTCCTGAGGAGC
GGAGCGATACCCCTGAAGTTCATCCTCCACTGCCCATTTCCCAGTCCCCAGAAAATGAGAGTAATGATAGGAGAAGCAGAAGGTATTCAG
TGTCGGAGAGAAGTTTTGGATCTAGAACGACGAAAAAATTATCAACTCTACAAAGTGCCCCCCAGCAGCAGACCTCCTCGTCTCCACCTC
CACCTCTGCTGACTCCACCGCCACCACTGCAGCCAGCCTCCAGTATCTCTGACCACACACCTTGGCTTATGCCTCCAACAATCCCCTTAG
CATCACCATTTTTGCCTGCTTCCACTGCTCCTATGCAAGGGAAGCGAAAATCTATTTTGCGAGAACCGACATTTAGGTGGACTTCTTTAA
AGCATTCTAGGTCAGAGCCACAATACTTTTCCTCAGCAAAGTATGCCAAAGAAGGTCTTATTCGCAAACCAATATTTGATAATTTCCGAC
CCCCTCCACTAACTCCCGAGGACGTTGGCTTTGCATCTGGTTTTTCTGCATCTGGTACCGCTGCTTCAGCCCGATTGTTTTCGCCACTCC
ATTCTGGAACAAGGTTTGATATGCACAAAAGGAGCCCTCTTCTGAGAGCTCCAAGATTTACTCCAAGTGAGGCTCACTCTAGAATATTTG
AGTCTGTAACCTTGCCTAGTAATCGAACTTCTGCTGGAACATCTTCTTCAGGAGTATCCAATAGAAAAAGGAAAAGAAAAGTGTTTAGTC
CTATTCGATCTGAACCAAGATCTCCTTCTCACTCCATGAGGACAAGAAGTGGAAGGCTTAGTAGTTCTGAGCTCTCACCTCTCACCCCCC
CGTCTTCTGTCTCTTCCTCGTTAAGCATTTCTGTTAGTCCTCTTGCCACTAGTGCCTTAAACCCAACTTTTACTTTTCCTTCTCATTCCC
TGACTCAGTCTGGGGAATCTGCAGAGAAAAATCAGAGACCAAGGAAGCAGACTAGTGCTCCGGCAGAGCCATTTTCATCAAGTAGTCCTA
CTCCTCTCTTCCCTTGGTTTACCCCAGGCTCTCAGACTGAAAGAGGGAGAAATAAAGACAAGGCCCCCGAGGAGCTGTCCAAAGATCGAG
ATGCTGACAAGAGCGTGGAGAAGGACAAGAGTAGAGAGAGAGACCGGGAGAGAGAAAAGGAGAATAAGCGGGAGTCAAGGAAAGAGAAAA
GGAAAAAGGGATCAGAAATTCAGAGTAGTTCTGCTTTGTATCCTGTGGGTAGGGTTTCCAAAGAGAAGGTTGTTGGTGAAGATGTTGCCA
CTTCATCTTCTGCCAAAAAAGCAACAGGGCGGAAGAAGTCTTCATCACATGATTCTGGGACTGATATTACTTCTGTGACTCTTGGGGATA
CAACAGCTGTCAAAACCAAAATACTTATAAAGAAAGGGAGAGGAAATCTGGAAAAAACCAACTTGGACCTCGGCCCAACTGCCCCATCCC
TGGAGAAGGAGAAAACCCTCTGCCTTTCCACTCCTTCATCTAGCACTGTTAAACATTCCACTTCCTCCATAGGCTCCATGTTGGCTCAGG
CAGACAAGCTTCCAATGACTGACAAGAGGGTTGCCAGCCTCCTAAAAAAGGCCAAAGCTCAGCTCTGCAAGATTGAGAAGAGTAAGAGTC
TTAAACAAACCGACCAGCCCAAAGCACAGGGTCAAGAAAGTGACTCATCAGAGACCTCTGTGCGAGGACCCCGGATTAAACATGTCTGCA
GAAGAGCAGCTGTTGCCCTTGGCCGAAAACGAGCTGTGTTTCCTGATGACATGCCCACCCTGAGTGCCTTACCATGGGAAGAACGAGAAA
AGATTTTGTCTTCCATGGGGAATGATGACAAGTCATCAATTGCTGGCTCAGAAGATGCTGAACCTCTTGCTCCACCCATCAAACCAATTA
AACCTGTCACTAGAAACAAGGCACCCCAGGAACCTCCAGTAAAGAAAGGACGTCGATCGAGGCGGTGTGGGCAGTGTCCCGGCTGCCAGG
TGCCTGAGGACTGTGGTGTTTGTACTAATTGCTTAGATAAGCCCAAGTTTGGTGGTCGCAATATAAAGAAGCAGTGCTGCAAGATGAGAA
AATGTCAGAATCTACAATGGATGCCTTCCAAAGCCTACCTGCAGAAGCAAGCTAAAGCTGTGAAAAAGAAAGAGAAAAAGTCTAAGACCA
GTGAAAAGAAAGACAGCAAAGAGAGCAGTGTTGTGAAGAACGTGGTGGACTCTAGTCAGAAACCTACCCCATCAGCAAGAGAGGATCCTG
CCCCAAAGAAAAGCAGTAGTGAGCCTCCTCCACGAAAGCCCGTCGAGGAAAAGAGTGAAGAAGGGAATGTCTCGGCCCCTGGGCCTGAAT
CCAAACAGGCCACCACTCCAGCTTCCAGGAAGTCAAGCAAGCAGGTCTCCCAGCCAGCACTGGTCATCCCGCCTCAGCCACCTACTACAG
GACCGCCAAGAAAAGAAGTTCCCAAAACCACTCCTAGTGAGCCCAAGAAAAAGCAGCCTCCACCACCAGAATCAGGTCCAGAGCAGAGCA
AACAGAAAAAAGTGGCTCCCCGCCCAAGTATCCCTGTAAAACAAAAACCAAAAGAAAAGGTGGAACGGCCGCCTTCTCCATTCTCCATGG
CCCCACAAGCTTCCCTTCCCCCGGTGCCACCACGACTTGACCTTCTGCCGCAGCGAGTATGTGTTCCCTCAAGTGCTTCTGCTCTTGGAA
CTGCTTCTAAGGCTGCTTCTGGCTCCCTTCATAAAGACAAACCATTGCCAGTACCTCCCACACTTCGAGATCTTCCACCACCACCGCCTC
CAGACCGGCCATATTCTGTTGGAGCAGAATCCCGACCTCAAAGACGCCCCTTGCCTTGTACACCAGGCGACTGTCCCTCCAGAGACAAAC
TGCCCCCTGTCCCCTCTAGCCGCCTTGGAGACTCATGGCTGCCCCGGCCAATCCCCAAAGTACCAGTATCTGCCCCAAGTTCCAGTGATC
CCTGGACAGGAAGAGAATTAACCAACCGGCACTCACTTCCATTTTCATTGCCCTCACAAATGGAGCCCAGACCAGATGTGCCTAGGCTCG
GAAGCACGTTCAGTCTGGATACCTCCATGAGTATGAATAGCAGCCCATTAGTAGGTCCAGAGTGTGACCACCCCAAAATCAAACCTTCCT
CATCTGCCAATGCCATTTATTCTCTGGCTGCCAGACCTCTTCCTGTGCCAAAACTGCCACCTGGGGAGCAATGTGAGGGTGAAGAGGACA
CAGAGTACATGACTCCCTCTTCCAGGCCTCTACGGCCTTTGGATACATCCCAGAGTTCACGAGCATGTGATTGCGACCAGCAGATTGATA
GCTGTACGTATGAAGCAATGTATAATATTCAGTCCCAGGCGCCATCTATCACCGAGAGCAGCACCTTTGGTGAAGGGAATTTGGCCGCAG
CCCATGCCAACACTGGTCCCGAGGAGTCAGAAAATGAGGATGATGGGTATGATGTCCCAAAGCCACCTGTGCCGGCCGTGCTGGCCCGCC
GAACTCTCTCAGATATCTCTAATGCCAGCTCCTCCTTTGGCTGGTTGTCTCTGGATGGTGATCCTACAACAAATGTCACTGAAGGTTCCC
AAGTTCCCGAGAGGCCTCCAAAACCATTCCCGCGGAGAATCAACTCTGAACGGAAAGCTGGCAGCTGTCAGCAAGGTAGTGGTCCTGCCG
CCTCTGCTGCCACCGCCTCACCTCAGCTCTCCAGTGAGATCGAGAACCTCATGAGTCAGGGGTACTCCTACCAGGACATCCAGAAAGCTT
TGGTCATTGCCCAGAACAACATCGAGATGGCCAAAAACATCCTCCGGGAATTTGTTTCCATTTCTTCTCCTGCCCATGTAGCTACCTAGC
ACACCATCTCCCTGCTGCAGGTTTAGAGGACCAGTGAGTTGGGAGTTATTACTCAAGTGGCACCTAGAAGGGCAGGAGTTCCTTTGGTGA
CTTCACAGTGAAGTCTTGCCCTCTCTGTGGGATATCACATCAGTGGTTCCAAGATTTCAAAGTGGTGAAATGAAAATGGAGCAGCTAGTA
TGTTTTATTATTTTATGGGTCTTGAGTGCATTTGAAGGTGTCCTTCAGTTCCCACGTAGAGAGAGTGTGGATTATATTACATGATAACCT
ACCTGGGGAACAGTCCAGAAAGCTATAGAACAAGTATTTTGCTGGAAATCCTAATTGAGGACTTAAGACTTCCTGGGTTAAGGATGTGGC
CGTGTGTGTGTGTGTCTGCCTGTGGTTGTATGTGTCCTTGTGATTATAAGATTAACCTGCTGTGTGTGTTAATTCCAGGCAGGGAATTAG
CACAAAAGGTTTAGGAAGGAATCTTTTTTTAAAGACTTCCATCTACTGTGGTATTATACCCAAGCCTAGTGTGTATTACAACTTCAACAC
TCCCCTTTGGCTTATATTACCATGTGCATAGCTAAAGTCTTCTATTTTTAGAACACCTTCTGTCTGTTCTTTCCCCATCAACTCCTTCCT
CATCCTTCTTGGTGTTCTGTCATGGGCCATGGGCTTGCTATGGCCAGCCTTACTGAGGCCAAGCAGCTTATGGGATGTTCTTTATTGTGT
GTGATGGTATTGGTTTGTTTGGTAGATAAGTGGGAGGAAAAGTACTGTTGCTACACTATTATAGGCATGTTTGATACTAGCAGCTAACAC
TGGTCACTCCAAAGCACTGTTTCTATAGGAACATTGAAGCTATTAAGATGTTTTGATTATCCTAATTACATAATGACCGATTTGAGATAG
AGGCCTTTAAATACATTCCATGCCCTCCCCAGAAAATAGTCTGTGGGAGTCAGTTGCCTTGGTGCCAGGTATGTGTTCTGATGTAGGTCA
TGAGTCTTTCTACTTAATGGGAAGGGAAGAACATTTGTTTCCAGGATGACTTTCTGGCCAGAATACCGGAAAGCTTTTAGGAAGCTTCGT
TCACATGCTATTTAAATGCACAAAATAGACAGTAAGGATTTATCTGTTCAGTTTTTCTTCCCAGTGAATTAATTTCAGCTTATATGGGTG
TCTTCATTTGAACATGAGGAATATTAGGTTATATTTTCAGCAGTGGTTTTTTCCTTTGCCCTTTAAGGAGTGGGGATAATGTCCACGGTG
GCCCAGCCTCTTGCTGATGGCACCTTCCCTGCATTGCTGCCTCCCGATGATGTGGTTCTTTTCTTGTGCCTGTGGCTTTGGGAATGTAAC
ATCTCTTTCCTCCTTTCCTTCCCTTTTCCTCTTCACCTGAGGTCCTAAATACTCTCTGTAATTACTGTGTTCTTCACGGTAATTAGACAT
CATTCAGTGAATAAATTACTGTAGTCAAAGACAGTATGGGCTGGCAGTTTGTGTAATTGCAAGTTCATAAAGAGAATTGAGGGTCCAGTT
GGGAGAACTATTAGTCAGTTCTTTTATATGCTGATAAATGATCCCTCGAGTTCAGTTAGTATTCTGTCCAGAGTGTTTAGCTCACTTTCT
TAGCAGTGTGTAAGCTTTCTCCATGTCAGAAGCAAGCCTGCTCTTTGATAAATCTGTCTTCCTGAAAATCTAAATCATGCTTTTGTCTTT
AGATCTACACAGAAATGACCCTCCTTGGATCAGTTTTCTTTCCAGTCTAATCATCTTTGGAACTAAAACTTGTTCTAACTCGTCTCTTGG
CATTCAGCTACTCCTAGATCTTTTGGTTTTATCCCCTGGCCTCAGAGCCATTTATATTCCCAGAGTAGGCAGTACAGGATCTCGTGTTGA
TTTGCTGTGGTTACCCAGTGTCTTCTCTACATGGCATAAAGCGGCAAAGCCCACCATTAGGTGAGGCGGTCCCGAGTTGAGGTAGAGTGG
GGCAGAGGAAGATGGCAGTGAATATCAAACAGTAGACCGCCATCAACTTCTAACAGCCAGTACACACACTGTTTCATTTTGAGGTAACGT
TCAGTTTTGCATTTTGTTTAAATATTGAAGGCCTAGACAAAGAACTAGAAAAAAAAAAGCAGTTTCCAGGCCCATCCATATTGTAATTTT
TCTTTATCTGCAGATATTGCCTGTAGTCTAAAGATCTCTTTGGAAGACAAAGCATTGGCTATATATCTTTTGCCTTTTCCATGCATCTAA
ATCTTCTCTGGAGATTATCTCCCTACTGTGTAGGTTAAGGGCAGTCTCGACTTTTCCTTTTTTGAGTCCTGTGTGGCTCTTTGAATCAGC
GTGAAACTGAGGCTCCAGCTCCCTGTGTTGTGTGTGTGTGCCATCCATGGGCTTGGGTGTCAGTTTGTCACAGGTATCTGCCAGCATTCA
AGGTTTTGGATCATTTCATGAGGATCTTTCCTTTGACTGGGTGCTGTGAGGACACACCTGGGTCTGTGCCTGAGATTGCCAGGCAAGATT
AAGGAAAGTTTTCATGTGGCTTTTGTTTTGAGGTTATTCTCAAAACCTTAATTTCTTATATTTTCTGTTGACTAAGGCACCAGTAACCCA
TTCTTCACCCTCCATTTGTATGGCAATTTAAAAGTCTTTGGCTTTGCTCTGAATTTAATTAAAACTGCCTTTTATGAACAGACTTCGAGT
TTTGCCATTTTGGGCAAGCCCTTCCGCTTGTCCCTTCCTAGTGGCTAATAAAGTAAAAAAACCCACACTACTTTGTTCTCTTTTTCTCAT
ATTCATTGGGCTGTTGTATTCAGCCAGTCTCATGCTTTCCCTGGGTCTTCACGGATTGCTTTCCAAGCTGCCTTGTTGCGGGGTTGCTGC
AGAGCAGCAACTGGACCTTTCCAGCTGTCGCCATGTTCCTTCCACTAAAGTAGAGGGTTCTTAAAATGGAAAAACCTGTGGGCTCTTCAT
ATACCTCCCTTTAGTTAAGTAATAGACCAGGCAGCTTCTCATCTCAGCATTTACCTGTTAATATTTTTGTGAATAGTGCTCTCTACCTGT
GGGTGGCCGTTCTCTTCCACTTGCTCGTCTCCCCCCAGCCCCATTCTGCATAATCTACCATTCTTCTCCTCTCTTTCTCTTCTTATACAG
ACCCTCATTACTGGGGCCCAAGATGTGGGATACTACTGTTAGTATTATTTAACTATTTTGTAGATTTAAAAGATTTCTGGTTAAGGGAGG
TGGGGGTCACTGTTCATCACTCTTAAAATATGTGTTTTCTCTATAGAAAAGTAAAATGTGTTTATGGTCCCAAACAGTCAACTCACAAAT
TTTTATAACAAAATTTCCTTGTAAAAACTAGGGACCATCTATATATTCCCTTTAAGATCTAGTTCTTTTTGTAGGTGTTCAGCAATGGTG
ATAAAGCAGAATATTCTCCTACCTCACGTCATTAAAGTCAGAAGATTATAGACCTTCTCAAACTATAAGTCCCTCTTCTTGCCGTTGGCC
TTTCTGACTCTGGAATGACCACTGTTCATTGAAAAATAGTTTTCTGACTATTGGTCTGGCTCTAACAGTTTGTTTGTTCATCCAGCAAAT
GTTTATGAGTGATGACCATGTGCCAGAAATGTCAGGTATGTGTCCTTCCCTTGGCGCCACATAGTAGTTTACTAATGTTTGGGGGATTGT
ACTTGGACTGTCATAGCCTCTGCGTTTGACCTTAAAATAGCTCTTCCCAGTAAGATTGTGCAATTTTTATTCACAGCTCTTCCATGTAGA
CTTACCTTTCCTCATAGAGCTATCCTGGTTAATAACAGGCCAAGATTCTCCCATTATCCCCTGTTGTCTCCTGTAGCTTTGATAATGCCT
GGGAGATTCCTTGGTGTAAGTGTCATGGATACCGACTGTTTTTATGTTGGAATTTGTTCCAACATAATTAGAATCTGTTTGGTGAGTTGA
AAGGTAAGTTGGCTCAGAGTTGCACAGTAGGGCATTAAATGTTTAAGCAAAGCATCTGCCCACACTCCCCTTTCCAATCTAGTGCCTTCC
TTGAACTTTTTCCTGAGCTGCTACGTCCCTAATCCCCCTTGTTGGGAGGATTTTCGTATCACCCTTATGGGACCTGTCACCATGTCCTGT
ACTATTTGGAATTGGTTTTCCAGTCTTTCAACAACCGTTGTGGCTAACTATGTTTTAGAAGGGCTGGAGGTGTGGGCCCTGTCTTCGGGT
CTCAGGACCCAAAGATCCTTTAGTCAGTTGTTGGGTCTTCCAAGAGCCAGACATTAATACAGATTGAACTCCATCAGTCCCCTAATTGTC
AGCCTTTACCTCCCTCCCAGAGCAAGGAGTTTAGGGATTCTAAAGCTTAGTGTCCACACATCATTCTACCAGACCTTAGAGCTTTAGAAG
CTCAATCTAAAATACTGTAACTCAGCATAAACTATTACTATCACTCCTTTGAACTCAGTCTCCATGAGCAGTGTTTTGTTGGAAATACAT
AGAACGGCTTAATGCCTAGAGGGTGGTGGATAGTGAAGGACGGTCAAGGTTATATTTTTGACTGCTTAGGGATTCTTTGGATCCAAGAAA
CAGAAATGTTCAAGCGGAATAAAGGAGGGAGTGGAGTTGTGGTAAGGATGCAGGGTATTTCGCAGAACCCAGGACGGGAAGTGCCTTTGG
TTCTTGGGTGGAGCTGGAACTGCAGAGCTTTGCACCTAGTCCTTTCTCCCGCTTCACAGTCTGCTTATGGTATATGTGGCCCCCAAATAG
GCACTCTAGTCCTCAAGTCTACACCACCTTCCAACTCTGGGGATCACCATGAACAAATTCTCAATTTCCCATACTTAATTTTTTTTTTTT
TTGAGATGGAGTCTCGCTGTGTCGCCCAGGCTGGAGTGCAGTGGTGCAGTCTCAACTCACCACAACCTCTGCCTCCCAGGTTCAAGCAGT
TCTCTGCCTCAACCTCCCGAGTAGCTGGGATTACAGGCGCCTGCCACCATGCCCAGCTAATGTTCATATTTTTAGTAGAGACAGGGTTTC
ACCGTCTTGGCTAGGCTGGTCTTGAACTCCTGACCCTCATGATCCACCCACCTCGGCCTCCCAAAGTGCTAAGATTACAGGCGTGAGCCA
CCGCGCCCGGCCCATACTTCGTATTCTTAAAAAAAACTACACTCAGCCCAGCACATTGATCAAGTATCTATCTCTGAGCAGTTGGCCTTG
CCAGGGAGAGCAGAGATGTGGCAGGCTCCTTCAGCTGGAGACAGGGAGCTTCTCAGAGAAGTGAGCAGAGACTCCACAGACACCCTAAAA
AGGCTTCTACTCAAGAAGTAAAGCCACTACTCCTGCCTTTTTGCTTAGTGGACAGGAAGGCACAGGAGTTTGTCTGGGACATCATAGAAA
TTCTTAGGTTTAACTTAATTCTGGTCATTGTCTTCTTTATTTCCTGTTTTTCTTCCCTTTGTCAGTCTTCGCATCCAAGATTTCTTCCCT
CCCTCTTGTGGGCCAGCCTGTCCTGTTCCAGAGCTAGCCTGTTCCTGGGTAGCCTTCCTTAGCCTCCATTCAGCCTCAGGTCTTTTGCCT
TCTTCCGTGTTTATTTAGAGAGCAGAATCTAATAACGGGTTCCACTGTAGCCACTATCCATGGACTTCTGGGTCCTCTTCAGGTTTGAGT
GCTTGAAAATGTTCATTCTCTGGGCTTGTGGCCTGTCTCCTCCACTCTCCTCCTCACCCTCTCGCTCCTTCCTGTGTGAGGGCCGCTCTG
CAGTAATGTTCTCAGGCAAGCCTTCCTAGGCACCTCAGAAACTACTTTGCCAGAGCCAGTAAGAATATATAATATTGGAGCAGTTGCCAG
GATAGAAATTAAATATAGATTCCAGTTTAGGATAGAGTTTTTACCGAGAGCTCTTTAGACAGTATACCTGTGTCTTCTCTGGCAATTGCT
TTCATTTTAGTCCTATATAAAAGCTTTCCTTTTCTGTTTTTTTTTAAAACTATGCTTTTGCTTGCCTAAATCTTTTGATCTTATATTTCT
CTCATCTCAGAGCCTGTCCTGAGTTGTAAGGTATTTCATACTGCCTTACTTAAAAGTTTTTTAAACTACTAGAGTCATTTGATACACACA
GAAGTTACCTAATAATCCAAAGATGTCCATCAAGGGAGGAAGGGTGGGTCATCAGACTTTGCCTTTGATGTTGTAGACTAGGCTCCTGAG
TTAAGCAGCAGAGGGACAGCAGTGCCATGTGCCTTCACTGTGTCCCAGGAAATCTGGGTTGGTTCCAGTGGGAAATACCAGTATTTCTTG
GTTCTGGAAAGTAGCAAAAGAGTAGGAGATGGGGAAATAGGGATGGGGAGAGCAAGCCCCGCATGTCCATGGCGAGTCAGGTGGGGAGCA
CGGGTGGAAGGGCCGGCTGTTGACAGACAGACTAAGCTGTGTGGTGCTCTTGCCGCCCCTTCCTGGGTACAGAGCTTGAGAAAAATGCAG
CCGACCACTCCCTGTGTTTGTACAGAGCAAAGCCCAAAAGCCAACCTCAGATCTCCTGATTTGGCAGCTGAAGAAATCAGCAGAGTCCTG
ATTGCCTGATTCAGTCCCAAAAATGAATGTCAGGCCCCGCCCCCTCCCCACCAACATTGCCTCTCCTACATTCTCCTTCTGCCCCTAAAT
CAGACAGGAGGCCAGAGAGGAGTATTGCTCAATGCGTGCTATGTGCAACTCCTCAGGCCTTGTGCCACCTCCATGCTGAGCCCTGAAGCA
GGGTGTCCTGGGTGCCTGTGTGTCAGCTCCCTCCTCTCTACCTACCTCTGACCTTCTTGTGGGTGAGGGTGGCCATGCTTATGGCCATCT
TAAAACTGGAGAGGCAGAGAACTACTTATGAGTCTGTAGACCACGTGTTGTCTTCCATGGCCTGTTTCTCCTGCTGTCTGGGTGAGTGAG
CCTGCAACGCAATGCCCATGAGAGTAAATGCCTCCTGACCTACCCTGCTCAGCACTGTTCTAGTGTCTTGGCCTTGAAAGAAAAGCCTGA
CTTCCTGCTGACACATGTGGTAGGGGCATGGCAGCTATGAGGCACCTCCTACGTCTGTTTTCTGGCTGTGGTGACTTGGGATTTTTAACC
TTATATATCTTTTTCCTTTACTCAAAACAAAACAATTTTTAGCACACTGAAAAAAAAAAAAAGCCAAATGTTTTGTGCCTTTCTAAGGCA
GCACTGTATCCCAGGCTGCATTTTAGGACTTAATATGGAAATACCAGAGTCTGAGCTCCTCTACCTTGAGTTTCATTAGTCCTTAGTGTC
TAGGAGACAGGAAAGAATGCTCTCTGTGACTGGAGAGGTGACATGCAGGTGCAGTGTGTCTGGAGTCCCTTTCCCCTGCTGTGAGACTTC
AGTGGAGGAGAGAAGCATTGTACCCTGGGATCATTTGGTTGGTTCCAATCACAAGCTTAGTTATCAGGTTGCATGCCTTGTCTCCTGCAA
AAGACAGAATGTTTCACAATTCCCAGGTAAACTCTGGACCATTCCAAGTGTCCTAGCCTTCTGATGACATTAATTACCTAGTTGTGTCGA
GGAGTATAGGATGGACTCTCCTGAGAAGGGGAGGTTGGTGGCTTTGTCTTTTCTTTTTGCTGGATCCTGAACTGGTCTAGACCTCCTGCC
CCCACCCCCCAGCCCCCATCAGATGTGGCTGGCCTTTCATTTGAAGGCTTCAGACTTAAAGCATTAAGCAGCTAGTGCCCTCTGCAGGGC
CTGGTTTCCCCAGGGAAGGGCAGCAAGGAACATGGGACCAGAAGCCTGTCCTCAGTAATGTGACTATAGTGAGCTTTAGCAAAAGTTTTT
CTATATAATGACATCTTACTTATCTTTTACCCTTTCCTCAGTTTTCCCCTGCCTTTAACTAATAAAGAATTGGGAGACAGAAATTTTAAA
GTCCTCCTTATTCAAGATTTTGAAATTCTTAGCCTGGGAGTGCTGGAGAGAACCTGATGCTTTCTCCAGAATGAAGAGTCCCAATTTGTA
TATCAGTGTTAAGAAGAAAACAAAACAAACACATAGGTGAGATTTTCGTGGACTATTTTAAAAATGTGTCATTAATATAAAAAATTTATA
TTAGCAGTATTTAATCATTCTCACCTGTAAAGAATAAGAAAAACAGAAGGTAAATATTCTTACAGAGAATAGCAGAGCTTTAAGATTCAT
TTTCATTTTAAGTCCATTTTATTTTGCCAGTGTATTAATGTTTAGAAGTCTGTTTTACTAATGTTATTTATTAATTTTTTTTCATTTCCA

>43149_43149_6_KMT2A-CBL_KMT2A_chr11_118353213_ENST00000534358_CBL_chr11_119155677_ENST00000264033_length(amino acids)=1791AA_BP=7
MAHSCRWRFPARPGTTGGGGGGGRRGLGGAPRQRVPALLLPPGPPVGGGGPGAPPSPPAVAAAAAAAGSSGAGVPGGAAAASAASSSSAS
SSSSSSSSASSGPALLRVGPGFDAALQVSAAIGTNLRRFRAVFGESGGGGGSGEDEQFLGFGSDEEVRVRSPTRSPSVKTSPRKPRGRPR
SGSDRNSAILSDPSVFSPLNKSETKSGDKIKKKDSKSIEKKRGRPPTFPGVKIKITHGKDISELPKGNKEDSLKKIKRTPSATFQQATKI
KKLRAGKLSPLKSKFKTGKLQIGRKGVQIVRRRGRPPSTERIKTPSGLLINSELEKPQKVRKDKEGTPPLTKEDKTVVRQSPRRIKPVRI
IPSSKRTDATIAKQLLQRAKKGAQKKIEKEAAQLQGRKVKTQVKNIRQFIMPVVSAISSRIIKTPRRFIEDEDYDPPIKIARLESTPNSR
FSAPSCGSSEKSSAASQHSSQMSSDSSRSSSPSVDTSTDSQASEEIQVLPEERSDTPEVHPPLPISQSPENESNDRRSRRYSVSERSFGS
RTTKKLSTLQSAPQQQTSSSPPPPLLTPPPPLQPASSISDHTPWLMPPTIPLASPFLPASTAPMQGKRKSILREPTFRWTSLKHSRSEPQ
YFSSAKYAKEGLIRKPIFDNFRPPPLTPEDVGFASGFSASGTAASARLFSPLHSGTRFDMHKRSPLLRAPRFTPSEAHSRIFESVTLPSN
RTSAGTSSSGVSNRKRKRKVFSPIRSEPRSPSHSMRTRSGRLSSSELSPLTPPSSVSSSLSISVSPLATSALNPTFTFPSHSLTQSGESA
EKNQRPRKQTSAPAEPFSSSSPTPLFPWFTPGSQTERGRNKDKAPEELSKDRDADKSVEKDKSRERDREREKENKRESRKEKRKKGSEIQ
SSSALYPVGRVSKEKVVGEDVATSSSAKKATGRKKSSSHDSGTDITSVTLGDTTAVKTKILIKKGRGNLEKTNLDLGPTAPSLEKEKTLC
LSTPSSSTVKHSTSSIGSMLAQADKLPMTDKRVASLLKKAKAQLCKIEKSKSLKQTDQPKAQGQESDSSETSVRGPRIKHVCRRAAVALG
RKRAVFPDDMPTLSALPWEEREKILSSMGNDDKSSIAGSEDAEPLAPPIKPIKPVTRNKAPQEPPVKKGRRSRRCGQCPGCQVPEDCGVC
TNCLDKPKFGGRNIKKQCCKMRKCQNLQWMPSKAYLQKQAKAVKKKEKKSKTSEKKDSKESSVVKNVVDSSQKPTPSAREDPAPKKSSSE
PPPRKPVEEKSEEGNVSAPGPESKQATTPASRKSSKQVSQPALVIPPQPPTTGPPRKEVPKTTPSEPKKKQPPPPESGPEQSKQKKVAPR
PSIPVKQKPKEKVERPPSPFSMAPQASLPPVPPRLDLLPQRVCVPSSASALGTASKAASGSLHKDKPLPVPPTLRDLPPPPPPDRPYSVG
AESRPQRRPLPCTPGDCPSRDKLPPVPSSRLGDSWLPRPIPKVPVSAPSSSDPWTGRELTNRHSLPFSLPSQMEPRPDVPRLGSTFSLDT
SMSMNSSPLVGPECDHPKIKPSSSANAIYSLAARPLPVPKLPPGEQCEGEEDTEYMTPSSRPLRPLDTSQSSRACDCDQQIDSCTYEAMY
NIQSQAPSITESSTFGEGNLAAAHANTGPEESENEDDGYDVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTTNVTEGSQVPERPPK

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for KMT2A-CBL


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneCBLchr11:118353213chr11:119155677ENST00000264033816648_906477.0907.0CD2AP


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneKMT2Achr11:118353213chr11:119155677ENST00000354520+8351584_16001362.03932.0histone H3K4me3
HgeneKMT2Achr11:118353213chr11:119155677ENST00000389506+8361584_16001362.03970.0histone H3K4me3
HgeneKMT2Achr11:118353213chr11:119155677ENST00000534358+8361584_16001362.03973.0histone H3K4me3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for KMT2A-CBL


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for KMT2A-CBL


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource