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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:ANAPC7-PDE11A (FusionGDB2 ID:4317)

Fusion Gene Summary for ANAPC7-PDE11A

Fusion gene summary

Fusion gene information	Fusion gene name: ANAPC7-PDE11A
	Fusion gene ID: 4317
		Hgene	Tgene
	Gene symbol	ANAPC7	PDE11A
	Gene ID	51434	50940
	Gene name	anaphase promoting complex subunit 7	phosphodiesterase 11A
	Synonyms	APC7	PPNAD2
	Cytomap	12q24.11	2q31.2
	Type of gene	protein-coding	protein-coding
	Description	anaphase-promoting complex subunit 7cyclosome subunit 7	dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11AcAMP and cGMP cyclic nucleotide phosphodiesterase 11A
	Modification date	20200313	20200313
	UniProtAcc	Q9UJX3	.
	Ensembl transtripts involved in fusion gene	ENST00000450008, ENST00000455511, ENST00000481473,	ENST00000497003, ENST00000389683, ENST00000409504, ENST00000449286, ENST00000450799, ENST00000286063, ENST00000358450,
Fusion gene scores	* DoF score	20 X 12 X 4=960	8 X 5 X 6=240
	# samples	21	11
	** MAII score	log2(21/960*10)=-2.1926450779424 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(11/240*10)=-1.12553088208386 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: ANAPC7 [Title/Abstract] AND PDE11A [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	ANAPC7(110832906)-PDE11A(178592900), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	ANAPC7	GO:0070979	protein K11-linked ubiquitination	18485873

Fusion gene breakpoints across ANAPC7 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PDE11A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	OV	TCGA-31-1951-01A	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
ChimerDB4	OV	TCGA-31-1951	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-

Top

Fusion Gene ORF analysis for ANAPC7-PDE11A

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000450008	ENST00000497003	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-5UTR	ENST00000450008	ENST00000497003	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
5CDS-5UTR	ENST00000455511	ENST00000497003	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-5UTR	ENST00000455511	ENST00000497003	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000450008	ENST00000389683	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000450008	ENST00000389683	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000450008	ENST00000409504	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000450008	ENST00000409504	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000450008	ENST00000449286	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000450008	ENST00000449286	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000450008	ENST00000450799	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000450008	ENST00000450799	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000455511	ENST00000389683	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000455511	ENST00000389683	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000455511	ENST00000409504	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000455511	ENST00000409504	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000455511	ENST00000449286	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000455511	ENST00000449286	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000455511	ENST00000450799	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
5CDS-intron	ENST00000455511	ENST00000450799	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
In-frame	ENST00000450008	ENST00000286063	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
In-frame	ENST00000450008	ENST00000286063	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
In-frame	ENST00000450008	ENST00000358450	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
In-frame	ENST00000450008	ENST00000358450	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
In-frame	ENST00000455511	ENST00000286063	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
In-frame	ENST00000455511	ENST00000286063	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
In-frame	ENST00000455511	ENST00000358450	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
In-frame	ENST00000455511	ENST00000358450	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
intron-3CDS	ENST00000481473	ENST00000286063	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
intron-3CDS	ENST00000481473	ENST00000286063	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
intron-3CDS	ENST00000481473	ENST00000358450	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
intron-3CDS	ENST00000481473	ENST00000358450	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
intron-5UTR	ENST00000481473	ENST00000497003	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
intron-5UTR	ENST00000481473	ENST00000497003	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
intron-intron	ENST00000481473	ENST00000389683	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
intron-intron	ENST00000481473	ENST00000389683	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
intron-intron	ENST00000481473	ENST00000409504	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
intron-intron	ENST00000481473	ENST00000409504	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
intron-intron	ENST00000481473	ENST00000449286	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
intron-intron	ENST00000481473	ENST00000449286	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-
intron-intron	ENST00000481473	ENST00000450799	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-
intron-intron	ENST00000481473	ENST00000450799	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000455511	ANAPC7	chr12	110832906	-	ENST00000286063	PDE11A	chr2	178592900	-	7680	511	1	1524	507
ENST00000455511	ANAPC7	chr12	110832906	-	ENST00000358450	PDE11A	chr2	178592900	-	2863	511	1	1524	507
ENST00000450008	ANAPC7	chr12	110832906	-	ENST00000286063	PDE11A	chr2	178592900	-	7680	511	1	1524	507
ENST00000450008	ANAPC7	chr12	110832906	-	ENST00000358450	PDE11A	chr2	178592900	-	2863	511	1	1524	507
ENST00000455511	ANAPC7	chr12	110832905	-	ENST00000286063	PDE11A	chr2	178592900	-	7680	511	1	1524	507
ENST00000455511	ANAPC7	chr12	110832905	-	ENST00000358450	PDE11A	chr2	178592900	-	2863	511	1	1524	507
ENST00000450008	ANAPC7	chr12	110832905	-	ENST00000286063	PDE11A	chr2	178592900	-	7680	511	1	1524	507
ENST00000450008	ANAPC7	chr12	110832905	-	ENST00000358450	PDE11A	chr2	178592900	-	2863	511	1	1524	507

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000455511	ENST00000286063	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-	0.000237525	0.9997625
ENST00000455511	ENST00000358450	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-	0.000785881	0.99921405
ENST00000450008	ENST00000286063	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-	0.000237525	0.9997625
ENST00000450008	ENST00000358450	ANAPC7	chr12	110832906	-	PDE11A	chr2	178592900	-	0.000785881	0.99921405
ENST00000455511	ENST00000286063	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-	0.000237525	0.9997625
ENST00000455511	ENST00000358450	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-	0.000785881	0.99921405
ENST00000450008	ENST00000286063	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-	0.000237525	0.9997625
ENST00000450008	ENST00000358450	ANAPC7	chr12	110832905	-	PDE11A	chr2	178592900	-	0.000785881	0.99921405

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Fusion Genomic Features for ANAPC7-PDE11A

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ANAPC7-PDE11A

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:110832906/chr2:178592900)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
ANAPC7 Q9UJX3	.
FUNCTION: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. {ECO:0000269\|PubMed:18485873}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

135_168

170

538.0

Repeat

Note=TPR 1

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

135_168

170

600.0

Repeat

Note=TPR 1

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

135_168

170

538.0

Repeat

Note=TPR 1

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

135_168

170

600.0

Repeat

Note=TPR 1

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000358450

402_558

346

684.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000358450

588_912

346

684.0

Domain

PDEase

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000389683

217_370

152

490.0

Domain

Note=GAF 1

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000389683

402_558

152

490.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000389683

588_912

152

490.0

Domain

PDEase

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000409504

402_558

238

663.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000409504

588_912

238

663.0

Domain

PDEase

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000449286

402_558

238

576.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000449286

588_912

238

576.0

Domain

PDEase

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000358450

402_558

346

684.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000358450

588_912

346

684.0

Domain

PDEase

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000389683

217_370

152

490.0

Domain

Note=GAF 1

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000389683

402_558

152

490.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000389683

588_912

152

490.0

Domain

PDEase

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000409504

402_558

238

663.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000409504

588_912

238

663.0

Domain

PDEase

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000449286

402_558

238

576.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000449286

588_912

238

576.0

Domain

PDEase

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

203_236

170

538.0

Repeat

Note=TPR 2

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

237_270

170

538.0

Repeat

Note=TPR 3

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

271_304

170

538.0

Repeat

Note=TPR 4

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

373_406

170

538.0

Repeat

Note=TPR 5

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

407_440

170

538.0

Repeat

Note=TPR 6

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

441_475

170

538.0

Repeat

Note=TPR 7

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

476_508

170

538.0

Repeat

Note=TPR 8

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

509_542

170

538.0

Repeat

Note=TPR 9

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000450008

543_565

170

538.0

Repeat

Note=TPR 10

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

203_236

170

600.0

Repeat

Note=TPR 2

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

237_270

170

600.0

Repeat

Note=TPR 3

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

271_304

170

600.0

Repeat

Note=TPR 4

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

373_406

170

600.0

Repeat

Note=TPR 5

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

407_440

170

600.0

Repeat

Note=TPR 6

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

441_475

170

600.0

Repeat

Note=TPR 7

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

476_508

170

600.0

Repeat

Note=TPR 8

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

509_542

170

600.0

Repeat

Note=TPR 9

Hgene

ANAPC7

chr12:110832905

chr2:178592900

ENST00000455511

543_565

170

600.0

Repeat

Note=TPR 10

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

203_236

170

538.0

Repeat

Note=TPR 2

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

237_270

170

538.0

Repeat

Note=TPR 3

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

271_304

170

538.0

Repeat

Note=TPR 4

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

373_406

170

538.0

Repeat

Note=TPR 5

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

407_440

170

538.0

Repeat

Note=TPR 6

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

441_475

170

538.0

Repeat

Note=TPR 7

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

476_508

170

538.0

Repeat

Note=TPR 8

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

509_542

170

538.0

Repeat

Note=TPR 9

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000450008

543_565

170

538.0

Repeat

Note=TPR 10

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

203_236

170

600.0

Repeat

Note=TPR 2

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

237_270

170

600.0

Repeat

Note=TPR 3

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

271_304

170

600.0

Repeat

Note=TPR 4

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

373_406

170

600.0

Repeat

Note=TPR 5

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

407_440

170

600.0

Repeat

Note=TPR 6

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

441_475

170

600.0

Repeat

Note=TPR 7

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

476_508

170

600.0

Repeat

Note=TPR 8

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

509_542

170

600.0

Repeat

Note=TPR 9

Hgene

ANAPC7

chr12:110832906

chr2:178592900

ENST00000455511

543_565

170

600.0

Repeat

Note=TPR 10

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000286063

217_370

596

934.0

Domain

Note=GAF 1

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000286063

402_558

596

934.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000286063

588_912

596

934.0

Domain

PDEase

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000358450

217_370

346

684.0

Domain

Note=GAF 1

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000409504

217_370

238

663.0

Domain

Note=GAF 1

Tgene

PDE11A

chr12:110832905

chr2:178592900

ENST00000449286

217_370

238

576.0

Domain

Note=GAF 1

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000286063

217_370

596

934.0

Domain

Note=GAF 1

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000286063

402_558

596

934.0

Domain

Note=GAF 2

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000286063

588_912

596

934.0

Domain

PDEase

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000358450

217_370

346

684.0

Domain

Note=GAF 1

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000409504

217_370

238

663.0

Domain

Note=GAF 1

Tgene

PDE11A

chr12:110832906

chr2:178592900

ENST00000449286

217_370

238

576.0

Domain

Note=GAF 1

Top

Fusion Gene Sequence for ANAPC7-PDE11A

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>4317_4317_1_ANAPC7-PDE11A_ANAPC7_chr12_110832905_ENST00000450008_PDE11A_chr2_178592900_ENST00000286063_length(transcript)=7680nt_BP=511nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA
ACATGTTTTAACCTTACAACTCTTTGTTCAAATAAATCTTTCAATGAATCCCCAACATATAAAACGTCAAAAAGCTGAATTCCTATGTGA
ATTATAAGCAGGGTTTGGACATCCAGAGCACCTACAAACCTTCATCTCTTTGATTACGTACATGGGGGTCCACAGGGACTCTGAAGAGTT
TGAAAATCCCTGGCCTAGATTAAACCTGAGAGCCATTCTAGCTCTTAAAAAAATCTGAAATTTACAAACCATTTTTCTTGTTATTGTTTT
TGTTTCTTTGTTTGTTTGTTTTTTGAGACTGAGTTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTTACTGCAAC
CTCTGCTTCCTGGGTTCAAGCAATTCTCCAGCCTCAACCTCCTGAGAAGCTGGGATTACAGGTGCCTGCCACCACGCCTGGCTAATTTTT
GTACTTTTAGTAGACACAGGGTTTCACCATGTTTGCCAGGCTGATCTCAAACTCCTGACCTCAGGTGAGCCACCCACCTCTGCCTCCGAA
AGTGCTGGGATTACAGGCGTGAGCCACCGTACCCGGCCCTTGTTATTGTTATTAATCATTATCAATCATTAACTTTACAGATATTAAAGA
AATAGGGGCCATGTTCTACATGCGACATTGTTTTCCTGGCACACAGTAGACAATTCAGGAAATGTCTGAAGAAGGAATGGGTAAAATTAA
GATACCAAAATGGAATTGAGGGGAGAGCAGGTAATTGTAGAGAAAAAGACTCTTTATGGCAAGAAACAAAGTAAAAGAAATGTATAGACC
GGGCGCGGTGGCTCACGCCTGTAATCCCAGCAATTTGGAAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCGTCCTGGCTA
ACACGGTGAAACCCTGTCTCTACTAAAAAACACAAAACAAATTAGCCAGGCGCGGTGGCAGGCGTCTGTAGTCCCAGCTACTGGGGAGGC
TGAGGCAAGAGAATGGCGGGAACCCGCGAGGCGGAGCTTGCAGTGAGTCGAGATCACGTCACTGCCCTCCAGCCTGGGCGACCAGCGAGA
CTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTATAAACCAGACTAAGAGGGGAATAAAAGCAAGAAGAAAAAGAAA
CGTAAGAACACCAGTAAAGGAAAGACAGGGACCGAGACAGGTGGTTAAGGGAAATGAAAAAAAAAAAAAAAAGGTGAAAGTCAATCCAAA
CAAAGAAAAATGGCACTTCCAACCAAAAAAAATGAAGGTGTAGAACCCTGTCATCAATTGCTCAGAAAAGAGAGACACTTGAGCAGGGAG
GGGTTTGAGAAAGGGGAGAAGGAAGGAGTGAGAGCCCTAAAAAATAATGTTCCTAGCTACCCTTTACAGCTGTCTCTGCAGGGAAGACTG
GAGAAAGTAGAGGGGGAAATGAATGCAGGAAGAAACTGCCTCTGCAGAGCAGGTAAGAGGAGGTTGTTCAGATTTATGGATTTTATTAAG
CCAGTTTTCTGTATCACTCTGCTATAAAGGAAAATAGCTTCTGCAGGGCTGTCTCTCCTCCTTCAGGTGGGGAACAAAGGGTGGGTGGAG
TCAGGGACAGAGTCTGGTCTGCGAGATCGTGACGTGTCTGCAGCTCCGAAGCACTGCAGGTGTTTCTGGGTAATGTGCCACATCATGTTT
ATATCACGAACGGGAATTGAAAATCAGTCTGTGTGAGGCAGAGATGAGCCCACATCTGTTATCCTCCCCAACAATAAATAAATAAATAGC
CCAGACAAATGGATGCCAGTCCATCTACAGCAACATTTTAAAGCATGTGCTTTATGACAAAACTGGACCCAGGGTCTGACAGAGACTGCA
GGCTGCCGTGAGCACTGTAGCTATCCTGAACATTGATGCTACATATTGCTAAGGGGAACATAATTTATAGCATAAACCCTACAAGCTTCC
ACTAAGGTTGAGTTTTCCTCTCATTTTCTTGCCGTTTTATTGGCTTCACTGCATGGTTGCCAATAGCAACATCCACTGGTAGCAAGGGGA
GTTCAACACCATTGCAATCTGCCATACAGTGGAGCCCTGACAATGTCAACCATCAATCTAGTAGCTGTTTGTAATTGCCTCCATCTATTT
CTCCTGTCTTGAGGTATCTTTCCTATTGTGGGTCAAGATTTAGAAACTGCTGACTAATGCCATGGGTCTGTGTCTCCATGACTATGAAGC
AGTGGACAGGAAGGTAGCAGCTTCCTGGTGCCAACAACCCCAGAGGTTAGAGGTTGAACTCTTGCGGGTTTCAGGCGTTTTTAATCCCTT
TTCTAAACAATTTATAATTTTGCAAGAATGTGAGGCATATGCAGTTATCCATATAATCTGCTTTTCCAAAAAAGAGAAAGGAAGTTTCCC
AGTCCTTATTATTAATGTTTATTTCCTATTGGAGAAAGACATTTGAAATATGAGCCTTCTTGTAAAAACTCAAACTGACCAGATTATGTT
TGCTTCCTCAGGTCTCTTGGCATTAATTGTTGAAATAACTTCATCCTACTTTTTCGATGAGATGTATTTTTTTCAGACATATTTATTCTT
ACTAGTCACTATGTAGCTATTATGTGCACAATCTACAATGTAGTGGCAATCCTGGTGGGTAGGGACAGCTTCACATACTGCAAAGGGTGC
CATTCAGTGCATAGCAGACTGGAACTCCCTCCTAGCTTGGCCACCAGCTGAACCTGTAATCTTAGGACTCTCCAAGTCTTAGAATCTCCA
TCTATTACATAAAAGCACTGACTTTTATTCAGTCCCCACACCAAAGGACCAAGACGTGTTTAGCTTTAAAGAAATTTTCCAGATAATTTT
CTTTTTTATTCTTCTCAAATAAAATAGCAACAAACCTAAAGCAGTCATCTTCTTAATAAAGACATAATAAAACTTACATATATGGGGTAG
ATGTAAGCACAATCATACTACAGATGTATCTTGAGCCTGTCTCTAATTATGATGAAAGATGTAGTCATCAATACAATTTAAAAAAAGATA
TGTCCTTTTTTTGAGACAGGGTCTTGCTCTGTCACCCAGGCTGGAGGGCAGTGGCACAATCACAGCCACTGCAGCCTTGACCTCTCCAAC
TTAAGTGATCTTTCCTGCCTCAGCCTCATGAGTAGCTGGGACCACAGGTGTGCACCACCACACCCAGCTAAATTTTGTATTGTTTGTAAA
GACGAGGCCTCACTATGCTGACCACACTGGTCTCGAACTCCTGGGCTCAAGCAATCCTCCTGCCTTGGCCTCCCAAAGTGTTAGGGTTAG
AGATATGAACCACCACACCCACCTTATATGTCCTTTTATTTCATAAAAAACAATTTTAGATTATCTGATATCACACATATCCCATAAATG
GTAGTCATTAATTTAGAAGTGAATTTATAAAGTTAAGAGAAGTTAAAATTGCACATGCATTTTGTTTCTAAAATCTGAGATGTCTATGCA
TTTCCAGGTATTGTATATTTGCAAATACATTGGGTTAGAAATCATCTTTAACATTTTGTGTTAGTGTAATAACAATATTATCTAATATTA
ATGCTGCCAGAATCCAGTTGCTTTTTCTGTGTATCAAAATTTATCATAACTTTTTCCACTTAACACTAGGTAATTAAACAGAATCTGCCC
AATTTATTCTGCAGTAAAATTATTTTAAAATCTATTTTTCCTGCTGACTCTTAGAAATTGCAGAAAGACAAAAACCAGTTTCATCTCCAG
TAATAGTGTGAAACAATTTCCTTCCAGTGGGACAGAAACCTAGACATACTAGGGAAAGATTTAAATATAAAGAAAAATGCCTTGGCTGAA
AAAAAAAAAAACCACCAAAACACAAAAAGGATTCATTAAAGCAACAGAACAAAACCTAATTTGGGACCCTAAAAACTCTGGCAATGCCAC
TGTAATGAAGTTTCATTATCTGCTTCAGAGTAACAGTCTCTGAAATTGTTATTCTGCTACATGCTGTAAAGAACTCCCAAAACTCAAATG
TATCAGGAAATGTAAAGGTTAAGTCTGACTACAAGAAGGCCAAAATTGCACCAGCTTCCTAAGTGAAGAATAATAGAATAAAACATATAG
AGGGCAGAAATAAAATGAGGTGTATCTGGAGAATTTCATGATGAGCATTTAGATTTAGCAATGCCCAATGTCATGCTGACACTGTTTGTC
ATGACCTTGTCTTCAGCTAGTAATTTGGGGTTGTACTTTTTTAAATTTAATTTTGAATGTTCTTGCATGTTTGGTACCTCTCTCCTCACT
GCTAAAGATAAATTGTTTATCTGTATAACATAACTACACCAATGTCATTTTTGTATACGCTAGTACACAAATGTGTTTTTTTATTAAGTA
ATGAAGTATTTGCTGTGAAAAATGTATTATTTGTGCCACCGTTTATATCTGTGTTCATTTTCTGTGTGTATATGCGTGTGTATTCGAATC
TCAATTTTTCTTTTACTCTAGTTTAGATTAAGACATATTTAGATGAAATTTTAAAAATAACATTGGAAATAGGAGGCTAAGTTTTGTTGA
GTCTCATTCCCTTGGGGGGAAATTGCTTTTGCCATTTTATTTTCATGTACAATAACCTAAAAAGGATCTCCTACTGACTTCCTTCCTAAT
TATTATTGTTTTACACGAAAGAAAGGAAATACGTTTTCAATTGAGTTGTTTGAAATCATTCACTTTGTGTAGATTTCCCAGACTGATGTT
TCATTGTAAGAATATTACATTATAGACAGGTTGGCCATTTCACAAGCAACTAATCCATAGTTTTGGAAGCCCGCTTTAAGAGACCTGAAT

>4317_4317_1_ANAPC7-PDE11A_ANAPC7_chr12_110832905_ENST00000450008_PDE11A_chr2_178592900_ENST00000286063_length(amino acids)=507AA_BP=170
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHD
KEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

--------------------------------------------------------------
>4317_4317_2_ANAPC7-PDE11A_ANAPC7_chr12_110832905_ENST00000450008_PDE11A_chr2_178592900_ENST00000358450_length(transcript)=2863nt_BP=511nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA

>4317_4317_2_ANAPC7-PDE11A_ANAPC7_chr12_110832905_ENST00000450008_PDE11A_chr2_178592900_ENST00000358450_length(amino acids)=507AA_BP=170
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHD
KEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

--------------------------------------------------------------
>4317_4317_3_ANAPC7-PDE11A_ANAPC7_chr12_110832905_ENST00000455511_PDE11A_chr2_178592900_ENST00000286063_length(transcript)=7680nt_BP=511nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA
ACATGTTTTAACCTTACAACTCTTTGTTCAAATAAATCTTTCAATGAATCCCCAACATATAAAACGTCAAAAAGCTGAATTCCTATGTGA
ATTATAAGCAGGGTTTGGACATCCAGAGCACCTACAAACCTTCATCTCTTTGATTACGTACATGGGGGTCCACAGGGACTCTGAAGAGTT
TGAAAATCCCTGGCCTAGATTAAACCTGAGAGCCATTCTAGCTCTTAAAAAAATCTGAAATTTACAAACCATTTTTCTTGTTATTGTTTT
TGTTTCTTTGTTTGTTTGTTTTTTGAGACTGAGTTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTTACTGCAAC
CTCTGCTTCCTGGGTTCAAGCAATTCTCCAGCCTCAACCTCCTGAGAAGCTGGGATTACAGGTGCCTGCCACCACGCCTGGCTAATTTTT
GTACTTTTAGTAGACACAGGGTTTCACCATGTTTGCCAGGCTGATCTCAAACTCCTGACCTCAGGTGAGCCACCCACCTCTGCCTCCGAA
AGTGCTGGGATTACAGGCGTGAGCCACCGTACCCGGCCCTTGTTATTGTTATTAATCATTATCAATCATTAACTTTACAGATATTAAAGA
AATAGGGGCCATGTTCTACATGCGACATTGTTTTCCTGGCACACAGTAGACAATTCAGGAAATGTCTGAAGAAGGAATGGGTAAAATTAA
GATACCAAAATGGAATTGAGGGGAGAGCAGGTAATTGTAGAGAAAAAGACTCTTTATGGCAAGAAACAAAGTAAAAGAAATGTATAGACC
GGGCGCGGTGGCTCACGCCTGTAATCCCAGCAATTTGGAAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCGTCCTGGCTA
ACACGGTGAAACCCTGTCTCTACTAAAAAACACAAAACAAATTAGCCAGGCGCGGTGGCAGGCGTCTGTAGTCCCAGCTACTGGGGAGGC
TGAGGCAAGAGAATGGCGGGAACCCGCGAGGCGGAGCTTGCAGTGAGTCGAGATCACGTCACTGCCCTCCAGCCTGGGCGACCAGCGAGA
CTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTATAAACCAGACTAAGAGGGGAATAAAAGCAAGAAGAAAAAGAAA
CGTAAGAACACCAGTAAAGGAAAGACAGGGACCGAGACAGGTGGTTAAGGGAAATGAAAAAAAAAAAAAAAAGGTGAAAGTCAATCCAAA
CAAAGAAAAATGGCACTTCCAACCAAAAAAAATGAAGGTGTAGAACCCTGTCATCAATTGCTCAGAAAAGAGAGACACTTGAGCAGGGAG
GGGTTTGAGAAAGGGGAGAAGGAAGGAGTGAGAGCCCTAAAAAATAATGTTCCTAGCTACCCTTTACAGCTGTCTCTGCAGGGAAGACTG
GAGAAAGTAGAGGGGGAAATGAATGCAGGAAGAAACTGCCTCTGCAGAGCAGGTAAGAGGAGGTTGTTCAGATTTATGGATTTTATTAAG
CCAGTTTTCTGTATCACTCTGCTATAAAGGAAAATAGCTTCTGCAGGGCTGTCTCTCCTCCTTCAGGTGGGGAACAAAGGGTGGGTGGAG
TCAGGGACAGAGTCTGGTCTGCGAGATCGTGACGTGTCTGCAGCTCCGAAGCACTGCAGGTGTTTCTGGGTAATGTGCCACATCATGTTT
ATATCACGAACGGGAATTGAAAATCAGTCTGTGTGAGGCAGAGATGAGCCCACATCTGTTATCCTCCCCAACAATAAATAAATAAATAGC
CCAGACAAATGGATGCCAGTCCATCTACAGCAACATTTTAAAGCATGTGCTTTATGACAAAACTGGACCCAGGGTCTGACAGAGACTGCA
GGCTGCCGTGAGCACTGTAGCTATCCTGAACATTGATGCTACATATTGCTAAGGGGAACATAATTTATAGCATAAACCCTACAAGCTTCC
ACTAAGGTTGAGTTTTCCTCTCATTTTCTTGCCGTTTTATTGGCTTCACTGCATGGTTGCCAATAGCAACATCCACTGGTAGCAAGGGGA
GTTCAACACCATTGCAATCTGCCATACAGTGGAGCCCTGACAATGTCAACCATCAATCTAGTAGCTGTTTGTAATTGCCTCCATCTATTT
CTCCTGTCTTGAGGTATCTTTCCTATTGTGGGTCAAGATTTAGAAACTGCTGACTAATGCCATGGGTCTGTGTCTCCATGACTATGAAGC
AGTGGACAGGAAGGTAGCAGCTTCCTGGTGCCAACAACCCCAGAGGTTAGAGGTTGAACTCTTGCGGGTTTCAGGCGTTTTTAATCCCTT
TTCTAAACAATTTATAATTTTGCAAGAATGTGAGGCATATGCAGTTATCCATATAATCTGCTTTTCCAAAAAAGAGAAAGGAAGTTTCCC
AGTCCTTATTATTAATGTTTATTTCCTATTGGAGAAAGACATTTGAAATATGAGCCTTCTTGTAAAAACTCAAACTGACCAGATTATGTT
TGCTTCCTCAGGTCTCTTGGCATTAATTGTTGAAATAACTTCATCCTACTTTTTCGATGAGATGTATTTTTTTCAGACATATTTATTCTT
ACTAGTCACTATGTAGCTATTATGTGCACAATCTACAATGTAGTGGCAATCCTGGTGGGTAGGGACAGCTTCACATACTGCAAAGGGTGC
CATTCAGTGCATAGCAGACTGGAACTCCCTCCTAGCTTGGCCACCAGCTGAACCTGTAATCTTAGGACTCTCCAAGTCTTAGAATCTCCA
TCTATTACATAAAAGCACTGACTTTTATTCAGTCCCCACACCAAAGGACCAAGACGTGTTTAGCTTTAAAGAAATTTTCCAGATAATTTT
CTTTTTTATTCTTCTCAAATAAAATAGCAACAAACCTAAAGCAGTCATCTTCTTAATAAAGACATAATAAAACTTACATATATGGGGTAG
ATGTAAGCACAATCATACTACAGATGTATCTTGAGCCTGTCTCTAATTATGATGAAAGATGTAGTCATCAATACAATTTAAAAAAAGATA
TGTCCTTTTTTTGAGACAGGGTCTTGCTCTGTCACCCAGGCTGGAGGGCAGTGGCACAATCACAGCCACTGCAGCCTTGACCTCTCCAAC
TTAAGTGATCTTTCCTGCCTCAGCCTCATGAGTAGCTGGGACCACAGGTGTGCACCACCACACCCAGCTAAATTTTGTATTGTTTGTAAA
GACGAGGCCTCACTATGCTGACCACACTGGTCTCGAACTCCTGGGCTCAAGCAATCCTCCTGCCTTGGCCTCCCAAAGTGTTAGGGTTAG
AGATATGAACCACCACACCCACCTTATATGTCCTTTTATTTCATAAAAAACAATTTTAGATTATCTGATATCACACATATCCCATAAATG
GTAGTCATTAATTTAGAAGTGAATTTATAAAGTTAAGAGAAGTTAAAATTGCACATGCATTTTGTTTCTAAAATCTGAGATGTCTATGCA
TTTCCAGGTATTGTATATTTGCAAATACATTGGGTTAGAAATCATCTTTAACATTTTGTGTTAGTGTAATAACAATATTATCTAATATTA
ATGCTGCCAGAATCCAGTTGCTTTTTCTGTGTATCAAAATTTATCATAACTTTTTCCACTTAACACTAGGTAATTAAACAGAATCTGCCC
AATTTATTCTGCAGTAAAATTATTTTAAAATCTATTTTTCCTGCTGACTCTTAGAAATTGCAGAAAGACAAAAACCAGTTTCATCTCCAG
TAATAGTGTGAAACAATTTCCTTCCAGTGGGACAGAAACCTAGACATACTAGGGAAAGATTTAAATATAAAGAAAAATGCCTTGGCTGAA
AAAAAAAAAAACCACCAAAACACAAAAAGGATTCATTAAAGCAACAGAACAAAACCTAATTTGGGACCCTAAAAACTCTGGCAATGCCAC
TGTAATGAAGTTTCATTATCTGCTTCAGAGTAACAGTCTCTGAAATTGTTATTCTGCTACATGCTGTAAAGAACTCCCAAAACTCAAATG
TATCAGGAAATGTAAAGGTTAAGTCTGACTACAAGAAGGCCAAAATTGCACCAGCTTCCTAAGTGAAGAATAATAGAATAAAACATATAG
AGGGCAGAAATAAAATGAGGTGTATCTGGAGAATTTCATGATGAGCATTTAGATTTAGCAATGCCCAATGTCATGCTGACACTGTTTGTC
ATGACCTTGTCTTCAGCTAGTAATTTGGGGTTGTACTTTTTTAAATTTAATTTTGAATGTTCTTGCATGTTTGGTACCTCTCTCCTCACT
GCTAAAGATAAATTGTTTATCTGTATAACATAACTACACCAATGTCATTTTTGTATACGCTAGTACACAAATGTGTTTTTTTATTAAGTA
ATGAAGTATTTGCTGTGAAAAATGTATTATTTGTGCCACCGTTTATATCTGTGTTCATTTTCTGTGTGTATATGCGTGTGTATTCGAATC
TCAATTTTTCTTTTACTCTAGTTTAGATTAAGACATATTTAGATGAAATTTTAAAAATAACATTGGAAATAGGAGGCTAAGTTTTGTTGA
GTCTCATTCCCTTGGGGGGAAATTGCTTTTGCCATTTTATTTTCATGTACAATAACCTAAAAAGGATCTCCTACTGACTTCCTTCCTAAT
TATTATTGTTTTACACGAAAGAAAGGAAATACGTTTTCAATTGAGTTGTTTGAAATCATTCACTTTGTGTAGATTTCCCAGACTGATGTT
TCATTGTAAGAATATTACATTATAGACAGGTTGGCCATTTCACAAGCAACTAATCCATAGTTTTGGAAGCCCGCTTTAAGAGACCTGAAT

>4317_4317_3_ANAPC7-PDE11A_ANAPC7_chr12_110832905_ENST00000455511_PDE11A_chr2_178592900_ENST00000286063_length(amino acids)=507AA_BP=170
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHD
KEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

--------------------------------------------------------------
>4317_4317_4_ANAPC7-PDE11A_ANAPC7_chr12_110832905_ENST00000455511_PDE11A_chr2_178592900_ENST00000358450_length(transcript)=2863nt_BP=511nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA

>4317_4317_4_ANAPC7-PDE11A_ANAPC7_chr12_110832905_ENST00000455511_PDE11A_chr2_178592900_ENST00000358450_length(amino acids)=507AA_BP=170
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHD
KEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

--------------------------------------------------------------
>4317_4317_5_ANAPC7-PDE11A_ANAPC7_chr12_110832906_ENST00000450008_PDE11A_chr2_178592900_ENST00000286063_length(transcript)=7680nt_BP=511nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA
ACATGTTTTAACCTTACAACTCTTTGTTCAAATAAATCTTTCAATGAATCCCCAACATATAAAACGTCAAAAAGCTGAATTCCTATGTGA
ATTATAAGCAGGGTTTGGACATCCAGAGCACCTACAAACCTTCATCTCTTTGATTACGTACATGGGGGTCCACAGGGACTCTGAAGAGTT
TGAAAATCCCTGGCCTAGATTAAACCTGAGAGCCATTCTAGCTCTTAAAAAAATCTGAAATTTACAAACCATTTTTCTTGTTATTGTTTT
TGTTTCTTTGTTTGTTTGTTTTTTGAGACTGAGTTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTTACTGCAAC
CTCTGCTTCCTGGGTTCAAGCAATTCTCCAGCCTCAACCTCCTGAGAAGCTGGGATTACAGGTGCCTGCCACCACGCCTGGCTAATTTTT
GTACTTTTAGTAGACACAGGGTTTCACCATGTTTGCCAGGCTGATCTCAAACTCCTGACCTCAGGTGAGCCACCCACCTCTGCCTCCGAA
AGTGCTGGGATTACAGGCGTGAGCCACCGTACCCGGCCCTTGTTATTGTTATTAATCATTATCAATCATTAACTTTACAGATATTAAAGA
AATAGGGGCCATGTTCTACATGCGACATTGTTTTCCTGGCACACAGTAGACAATTCAGGAAATGTCTGAAGAAGGAATGGGTAAAATTAA
GATACCAAAATGGAATTGAGGGGAGAGCAGGTAATTGTAGAGAAAAAGACTCTTTATGGCAAGAAACAAAGTAAAAGAAATGTATAGACC
GGGCGCGGTGGCTCACGCCTGTAATCCCAGCAATTTGGAAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCGTCCTGGCTA
ACACGGTGAAACCCTGTCTCTACTAAAAAACACAAAACAAATTAGCCAGGCGCGGTGGCAGGCGTCTGTAGTCCCAGCTACTGGGGAGGC
TGAGGCAAGAGAATGGCGGGAACCCGCGAGGCGGAGCTTGCAGTGAGTCGAGATCACGTCACTGCCCTCCAGCCTGGGCGACCAGCGAGA
CTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTATAAACCAGACTAAGAGGGGAATAAAAGCAAGAAGAAAAAGAAA
CGTAAGAACACCAGTAAAGGAAAGACAGGGACCGAGACAGGTGGTTAAGGGAAATGAAAAAAAAAAAAAAAAGGTGAAAGTCAATCCAAA
CAAAGAAAAATGGCACTTCCAACCAAAAAAAATGAAGGTGTAGAACCCTGTCATCAATTGCTCAGAAAAGAGAGACACTTGAGCAGGGAG
GGGTTTGAGAAAGGGGAGAAGGAAGGAGTGAGAGCCCTAAAAAATAATGTTCCTAGCTACCCTTTACAGCTGTCTCTGCAGGGAAGACTG
GAGAAAGTAGAGGGGGAAATGAATGCAGGAAGAAACTGCCTCTGCAGAGCAGGTAAGAGGAGGTTGTTCAGATTTATGGATTTTATTAAG
CCAGTTTTCTGTATCACTCTGCTATAAAGGAAAATAGCTTCTGCAGGGCTGTCTCTCCTCCTTCAGGTGGGGAACAAAGGGTGGGTGGAG
TCAGGGACAGAGTCTGGTCTGCGAGATCGTGACGTGTCTGCAGCTCCGAAGCACTGCAGGTGTTTCTGGGTAATGTGCCACATCATGTTT
ATATCACGAACGGGAATTGAAAATCAGTCTGTGTGAGGCAGAGATGAGCCCACATCTGTTATCCTCCCCAACAATAAATAAATAAATAGC
CCAGACAAATGGATGCCAGTCCATCTACAGCAACATTTTAAAGCATGTGCTTTATGACAAAACTGGACCCAGGGTCTGACAGAGACTGCA
GGCTGCCGTGAGCACTGTAGCTATCCTGAACATTGATGCTACATATTGCTAAGGGGAACATAATTTATAGCATAAACCCTACAAGCTTCC
ACTAAGGTTGAGTTTTCCTCTCATTTTCTTGCCGTTTTATTGGCTTCACTGCATGGTTGCCAATAGCAACATCCACTGGTAGCAAGGGGA
GTTCAACACCATTGCAATCTGCCATACAGTGGAGCCCTGACAATGTCAACCATCAATCTAGTAGCTGTTTGTAATTGCCTCCATCTATTT
CTCCTGTCTTGAGGTATCTTTCCTATTGTGGGTCAAGATTTAGAAACTGCTGACTAATGCCATGGGTCTGTGTCTCCATGACTATGAAGC
AGTGGACAGGAAGGTAGCAGCTTCCTGGTGCCAACAACCCCAGAGGTTAGAGGTTGAACTCTTGCGGGTTTCAGGCGTTTTTAATCCCTT
TTCTAAACAATTTATAATTTTGCAAGAATGTGAGGCATATGCAGTTATCCATATAATCTGCTTTTCCAAAAAAGAGAAAGGAAGTTTCCC
AGTCCTTATTATTAATGTTTATTTCCTATTGGAGAAAGACATTTGAAATATGAGCCTTCTTGTAAAAACTCAAACTGACCAGATTATGTT
TGCTTCCTCAGGTCTCTTGGCATTAATTGTTGAAATAACTTCATCCTACTTTTTCGATGAGATGTATTTTTTTCAGACATATTTATTCTT
ACTAGTCACTATGTAGCTATTATGTGCACAATCTACAATGTAGTGGCAATCCTGGTGGGTAGGGACAGCTTCACATACTGCAAAGGGTGC
CATTCAGTGCATAGCAGACTGGAACTCCCTCCTAGCTTGGCCACCAGCTGAACCTGTAATCTTAGGACTCTCCAAGTCTTAGAATCTCCA
TCTATTACATAAAAGCACTGACTTTTATTCAGTCCCCACACCAAAGGACCAAGACGTGTTTAGCTTTAAAGAAATTTTCCAGATAATTTT
CTTTTTTATTCTTCTCAAATAAAATAGCAACAAACCTAAAGCAGTCATCTTCTTAATAAAGACATAATAAAACTTACATATATGGGGTAG
ATGTAAGCACAATCATACTACAGATGTATCTTGAGCCTGTCTCTAATTATGATGAAAGATGTAGTCATCAATACAATTTAAAAAAAGATA
TGTCCTTTTTTTGAGACAGGGTCTTGCTCTGTCACCCAGGCTGGAGGGCAGTGGCACAATCACAGCCACTGCAGCCTTGACCTCTCCAAC
TTAAGTGATCTTTCCTGCCTCAGCCTCATGAGTAGCTGGGACCACAGGTGTGCACCACCACACCCAGCTAAATTTTGTATTGTTTGTAAA
GACGAGGCCTCACTATGCTGACCACACTGGTCTCGAACTCCTGGGCTCAAGCAATCCTCCTGCCTTGGCCTCCCAAAGTGTTAGGGTTAG
AGATATGAACCACCACACCCACCTTATATGTCCTTTTATTTCATAAAAAACAATTTTAGATTATCTGATATCACACATATCCCATAAATG
GTAGTCATTAATTTAGAAGTGAATTTATAAAGTTAAGAGAAGTTAAAATTGCACATGCATTTTGTTTCTAAAATCTGAGATGTCTATGCA
TTTCCAGGTATTGTATATTTGCAAATACATTGGGTTAGAAATCATCTTTAACATTTTGTGTTAGTGTAATAACAATATTATCTAATATTA
ATGCTGCCAGAATCCAGTTGCTTTTTCTGTGTATCAAAATTTATCATAACTTTTTCCACTTAACACTAGGTAATTAAACAGAATCTGCCC
AATTTATTCTGCAGTAAAATTATTTTAAAATCTATTTTTCCTGCTGACTCTTAGAAATTGCAGAAAGACAAAAACCAGTTTCATCTCCAG
TAATAGTGTGAAACAATTTCCTTCCAGTGGGACAGAAACCTAGACATACTAGGGAAAGATTTAAATATAAAGAAAAATGCCTTGGCTGAA
AAAAAAAAAAACCACCAAAACACAAAAAGGATTCATTAAAGCAACAGAACAAAACCTAATTTGGGACCCTAAAAACTCTGGCAATGCCAC
TGTAATGAAGTTTCATTATCTGCTTCAGAGTAACAGTCTCTGAAATTGTTATTCTGCTACATGCTGTAAAGAACTCCCAAAACTCAAATG
TATCAGGAAATGTAAAGGTTAAGTCTGACTACAAGAAGGCCAAAATTGCACCAGCTTCCTAAGTGAAGAATAATAGAATAAAACATATAG
AGGGCAGAAATAAAATGAGGTGTATCTGGAGAATTTCATGATGAGCATTTAGATTTAGCAATGCCCAATGTCATGCTGACACTGTTTGTC
ATGACCTTGTCTTCAGCTAGTAATTTGGGGTTGTACTTTTTTAAATTTAATTTTGAATGTTCTTGCATGTTTGGTACCTCTCTCCTCACT
GCTAAAGATAAATTGTTTATCTGTATAACATAACTACACCAATGTCATTTTTGTATACGCTAGTACACAAATGTGTTTTTTTATTAAGTA
ATGAAGTATTTGCTGTGAAAAATGTATTATTTGTGCCACCGTTTATATCTGTGTTCATTTTCTGTGTGTATATGCGTGTGTATTCGAATC
TCAATTTTTCTTTTACTCTAGTTTAGATTAAGACATATTTAGATGAAATTTTAAAAATAACATTGGAAATAGGAGGCTAAGTTTTGTTGA
GTCTCATTCCCTTGGGGGGAAATTGCTTTTGCCATTTTATTTTCATGTACAATAACCTAAAAAGGATCTCCTACTGACTTCCTTCCTAAT
TATTATTGTTTTACACGAAAGAAAGGAAATACGTTTTCAATTGAGTTGTTTGAAATCATTCACTTTGTGTAGATTTCCCAGACTGATGTT
TCATTGTAAGAATATTACATTATAGACAGGTTGGCCATTTCACAAGCAACTAATCCATAGTTTTGGAAGCCCGCTTTAAGAGACCTGAAT

>4317_4317_5_ANAPC7-PDE11A_ANAPC7_chr12_110832906_ENST00000450008_PDE11A_chr2_178592900_ENST00000286063_length(amino acids)=507AA_BP=170
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHD
KEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

--------------------------------------------------------------
>4317_4317_6_ANAPC7-PDE11A_ANAPC7_chr12_110832906_ENST00000450008_PDE11A_chr2_178592900_ENST00000358450_length(transcript)=2863nt_BP=511nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA

>4317_4317_6_ANAPC7-PDE11A_ANAPC7_chr12_110832906_ENST00000450008_PDE11A_chr2_178592900_ENST00000358450_length(amino acids)=507AA_BP=170
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHD
KEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

--------------------------------------------------------------
>4317_4317_7_ANAPC7-PDE11A_ANAPC7_chr12_110832906_ENST00000455511_PDE11A_chr2_178592900_ENST00000286063_length(transcript)=7680nt_BP=511nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA
ACATGTTTTAACCTTACAACTCTTTGTTCAAATAAATCTTTCAATGAATCCCCAACATATAAAACGTCAAAAAGCTGAATTCCTATGTGA
ATTATAAGCAGGGTTTGGACATCCAGAGCACCTACAAACCTTCATCTCTTTGATTACGTACATGGGGGTCCACAGGGACTCTGAAGAGTT
TGAAAATCCCTGGCCTAGATTAAACCTGAGAGCCATTCTAGCTCTTAAAAAAATCTGAAATTTACAAACCATTTTTCTTGTTATTGTTTT
TGTTTCTTTGTTTGTTTGTTTTTTGAGACTGAGTTTTCACTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTTACTGCAAC
CTCTGCTTCCTGGGTTCAAGCAATTCTCCAGCCTCAACCTCCTGAGAAGCTGGGATTACAGGTGCCTGCCACCACGCCTGGCTAATTTTT
GTACTTTTAGTAGACACAGGGTTTCACCATGTTTGCCAGGCTGATCTCAAACTCCTGACCTCAGGTGAGCCACCCACCTCTGCCTCCGAA
AGTGCTGGGATTACAGGCGTGAGCCACCGTACCCGGCCCTTGTTATTGTTATTAATCATTATCAATCATTAACTTTACAGATATTAAAGA
AATAGGGGCCATGTTCTACATGCGACATTGTTTTCCTGGCACACAGTAGACAATTCAGGAAATGTCTGAAGAAGGAATGGGTAAAATTAA
GATACCAAAATGGAATTGAGGGGAGAGCAGGTAATTGTAGAGAAAAAGACTCTTTATGGCAAGAAACAAAGTAAAAGAAATGTATAGACC
GGGCGCGGTGGCTCACGCCTGTAATCCCAGCAATTTGGAAGGCCGAGGCGGGCGGATCACGAGGTCAGGAGATCGAGACCGTCCTGGCTA
ACACGGTGAAACCCTGTCTCTACTAAAAAACACAAAACAAATTAGCCAGGCGCGGTGGCAGGCGTCTGTAGTCCCAGCTACTGGGGAGGC
TGAGGCAAGAGAATGGCGGGAACCCGCGAGGCGGAGCTTGCAGTGAGTCGAGATCACGTCACTGCCCTCCAGCCTGGGCGACCAGCGAGA
CTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGTATAAACCAGACTAAGAGGGGAATAAAAGCAAGAAGAAAAAGAAA
CGTAAGAACACCAGTAAAGGAAAGACAGGGACCGAGACAGGTGGTTAAGGGAAATGAAAAAAAAAAAAAAAAGGTGAAAGTCAATCCAAA
CAAAGAAAAATGGCACTTCCAACCAAAAAAAATGAAGGTGTAGAACCCTGTCATCAATTGCTCAGAAAAGAGAGACACTTGAGCAGGGAG
GGGTTTGAGAAAGGGGAGAAGGAAGGAGTGAGAGCCCTAAAAAATAATGTTCCTAGCTACCCTTTACAGCTGTCTCTGCAGGGAAGACTG
GAGAAAGTAGAGGGGGAAATGAATGCAGGAAGAAACTGCCTCTGCAGAGCAGGTAAGAGGAGGTTGTTCAGATTTATGGATTTTATTAAG
CCAGTTTTCTGTATCACTCTGCTATAAAGGAAAATAGCTTCTGCAGGGCTGTCTCTCCTCCTTCAGGTGGGGAACAAAGGGTGGGTGGAG
TCAGGGACAGAGTCTGGTCTGCGAGATCGTGACGTGTCTGCAGCTCCGAAGCACTGCAGGTGTTTCTGGGTAATGTGCCACATCATGTTT
ATATCACGAACGGGAATTGAAAATCAGTCTGTGTGAGGCAGAGATGAGCCCACATCTGTTATCCTCCCCAACAATAAATAAATAAATAGC
CCAGACAAATGGATGCCAGTCCATCTACAGCAACATTTTAAAGCATGTGCTTTATGACAAAACTGGACCCAGGGTCTGACAGAGACTGCA
GGCTGCCGTGAGCACTGTAGCTATCCTGAACATTGATGCTACATATTGCTAAGGGGAACATAATTTATAGCATAAACCCTACAAGCTTCC
ACTAAGGTTGAGTTTTCCTCTCATTTTCTTGCCGTTTTATTGGCTTCACTGCATGGTTGCCAATAGCAACATCCACTGGTAGCAAGGGGA
GTTCAACACCATTGCAATCTGCCATACAGTGGAGCCCTGACAATGTCAACCATCAATCTAGTAGCTGTTTGTAATTGCCTCCATCTATTT
CTCCTGTCTTGAGGTATCTTTCCTATTGTGGGTCAAGATTTAGAAACTGCTGACTAATGCCATGGGTCTGTGTCTCCATGACTATGAAGC
AGTGGACAGGAAGGTAGCAGCTTCCTGGTGCCAACAACCCCAGAGGTTAGAGGTTGAACTCTTGCGGGTTTCAGGCGTTTTTAATCCCTT
TTCTAAACAATTTATAATTTTGCAAGAATGTGAGGCATATGCAGTTATCCATATAATCTGCTTTTCCAAAAAAGAGAAAGGAAGTTTCCC
AGTCCTTATTATTAATGTTTATTTCCTATTGGAGAAAGACATTTGAAATATGAGCCTTCTTGTAAAAACTCAAACTGACCAGATTATGTT
TGCTTCCTCAGGTCTCTTGGCATTAATTGTTGAAATAACTTCATCCTACTTTTTCGATGAGATGTATTTTTTTCAGACATATTTATTCTT
ACTAGTCACTATGTAGCTATTATGTGCACAATCTACAATGTAGTGGCAATCCTGGTGGGTAGGGACAGCTTCACATACTGCAAAGGGTGC
CATTCAGTGCATAGCAGACTGGAACTCCCTCCTAGCTTGGCCACCAGCTGAACCTGTAATCTTAGGACTCTCCAAGTCTTAGAATCTCCA
TCTATTACATAAAAGCACTGACTTTTATTCAGTCCCCACACCAAAGGACCAAGACGTGTTTAGCTTTAAAGAAATTTTCCAGATAATTTT
CTTTTTTATTCTTCTCAAATAAAATAGCAACAAACCTAAAGCAGTCATCTTCTTAATAAAGACATAATAAAACTTACATATATGGGGTAG
ATGTAAGCACAATCATACTACAGATGTATCTTGAGCCTGTCTCTAATTATGATGAAAGATGTAGTCATCAATACAATTTAAAAAAAGATA
TGTCCTTTTTTTGAGACAGGGTCTTGCTCTGTCACCCAGGCTGGAGGGCAGTGGCACAATCACAGCCACTGCAGCCTTGACCTCTCCAAC
TTAAGTGATCTTTCCTGCCTCAGCCTCATGAGTAGCTGGGACCACAGGTGTGCACCACCACACCCAGCTAAATTTTGTATTGTTTGTAAA
GACGAGGCCTCACTATGCTGACCACACTGGTCTCGAACTCCTGGGCTCAAGCAATCCTCCTGCCTTGGCCTCCCAAAGTGTTAGGGTTAG
AGATATGAACCACCACACCCACCTTATATGTCCTTTTATTTCATAAAAAACAATTTTAGATTATCTGATATCACACATATCCCATAAATG
GTAGTCATTAATTTAGAAGTGAATTTATAAAGTTAAGAGAAGTTAAAATTGCACATGCATTTTGTTTCTAAAATCTGAGATGTCTATGCA
TTTCCAGGTATTGTATATTTGCAAATACATTGGGTTAGAAATCATCTTTAACATTTTGTGTTAGTGTAATAACAATATTATCTAATATTA
ATGCTGCCAGAATCCAGTTGCTTTTTCTGTGTATCAAAATTTATCATAACTTTTTCCACTTAACACTAGGTAATTAAACAGAATCTGCCC
AATTTATTCTGCAGTAAAATTATTTTAAAATCTATTTTTCCTGCTGACTCTTAGAAATTGCAGAAAGACAAAAACCAGTTTCATCTCCAG
TAATAGTGTGAAACAATTTCCTTCCAGTGGGACAGAAACCTAGACATACTAGGGAAAGATTTAAATATAAAGAAAAATGCCTTGGCTGAA
AAAAAAAAAAACCACCAAAACACAAAAAGGATTCATTAAAGCAACAGAACAAAACCTAATTTGGGACCCTAAAAACTCTGGCAATGCCAC
TGTAATGAAGTTTCATTATCTGCTTCAGAGTAACAGTCTCTGAAATTGTTATTCTGCTACATGCTGTAAAGAACTCCCAAAACTCAAATG
TATCAGGAAATGTAAAGGTTAAGTCTGACTACAAGAAGGCCAAAATTGCACCAGCTTCCTAAGTGAAGAATAATAGAATAAAACATATAG
AGGGCAGAAATAAAATGAGGTGTATCTGGAGAATTTCATGATGAGCATTTAGATTTAGCAATGCCCAATGTCATGCTGACACTGTTTGTC
ATGACCTTGTCTTCAGCTAGTAATTTGGGGTTGTACTTTTTTAAATTTAATTTTGAATGTTCTTGCATGTTTGGTACCTCTCTCCTCACT
GCTAAAGATAAATTGTTTATCTGTATAACATAACTACACCAATGTCATTTTTGTATACGCTAGTACACAAATGTGTTTTTTTATTAAGTA
ATGAAGTATTTGCTGTGAAAAATGTATTATTTGTGCCACCGTTTATATCTGTGTTCATTTTCTGTGTGTATATGCGTGTGTATTCGAATC
TCAATTTTTCTTTTACTCTAGTTTAGATTAAGACATATTTAGATGAAATTTTAAAAATAACATTGGAAATAGGAGGCTAAGTTTTGTTGA
GTCTCATTCCCTTGGGGGGAAATTGCTTTTGCCATTTTATTTTCATGTACAATAACCTAAAAAGGATCTCCTACTGACTTCCTTCCTAAT
TATTATTGTTTTACACGAAAGAAAGGAAATACGTTTTCAATTGAGTTGTTTGAAATCATTCACTTTGTGTAGATTTCCCAGACTGATGTT
TCATTGTAAGAATATTACATTATAGACAGGTTGGCCATTTCACAAGCAACTAATCCATAGTTTTGGAAGCCCGCTTTAAGAGACCTGAAT

>4317_4317_7_ANAPC7-PDE11A_ANAPC7_chr12_110832906_ENST00000455511_PDE11A_chr2_178592900_ENST00000286063_length(amino acids)=507AA_BP=170
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHD
KEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

--------------------------------------------------------------
>4317_4317_8_ANAPC7-PDE11A_ANAPC7_chr12_110832906_ENST00000455511_PDE11A_chr2_178592900_ENST00000358450_length(transcript)=2863nt_BP=511nt
GATGGACCCCGGCGACGCCGCCATTTTGGAGTCTTCCCTAAGGATCCTCTACCGGCTTTTCGAGTCAGTGCTGCCGCCGCTGCCCGCGGC
TTTGCAGAGCAGGATGAATGTGATAGACCACGTGCGGGACATGGCGGCCGCGGGGCTGCACTCCAACGTGCGGCTCCTCAGCAGCTTGTT
ACTTACAATGAGTAATAACAACCCTGAGTTATTCTCCCCACCTCAGAAGTACCAGCTTTTGGTGTATCATGCAGATTCTCTCTTTCATGA
TAAGGAATATCGGAATGCTGTGAGTAAGTATACCATGGCTTTACAGCAGAAGAAAGCGCTAAGTAAAACTTCAAAAGTGAGACCTTCAAC
TGGAAATTCTGCATCTACTCCACAAAGTCAGTGTCTTCCATCTGAAATTGAAGTGAAATACAAAATGGCTGAATGTTATACAATGCTAAA
ACAAGATAAAGATGCCATTGCTATACTTGATGGGATCCCTTCAAGACAAAGAACTCCCAAAGCAGCCAACATCCCTCTGGTGTCAGAACT
TGCCATCGATGACATTCATTTTGATGACTTTTCTCTCGACGTTGATGCCATGATCACAGCTGCTCTCCGGATGTTCATGGAGCTGGGGAT
GGTACAGAAATTTAAAATTGACTATGAGACACTGTGTAGGTGGCTTTTGACAGTGAGGAAAAACTATCGGATGGTTCTATACCACAACTG
GAGACATGCCTTCAACGTGTGTCAGCTGATGTTCGCGATGTTAACCACTGCTGGGTTTCAAGACATTCTGACCGAGGTGGAAATTTTAGC
GGTGATTGTGGGATGCCTGTGTCATGACCTCGACCACAGGGGAACCAACAATGCCTTCCAAGCTAAGAGTGGCTCTGCCCTGGCCCAACT
CTATGGAACCTCTGCTACCTTGGAGCATCACCATTTCAACCACGCCGTGATGATCCTTCAAAGTGAGGGTCACAATATCTTTGCTAACCT
GTCCTCCAAGGAATATAGTGACCTTATGCAGCTTTTGAAGCAGTCAATATTGGCAACAGACCTCACGCTGTACTTTGAGAGGAGAACTGA
ATTCTTTGAACTTGTCAGTAAAGGAGAATACGATTGGAACATCAAAAACCATCGTGATATATTTCGATCAATGTTAATGACAGCCTGTGA
CCTTGGAGCCGTGACCAAACCGTGGGAGATCTCCAGACAGGTGGCAGAACTTGTAACCAGTGAGTTCTTCGAACAAGGAGATCGGGAGAG
ATTAGAGCTCAAACTCACTCCTTCAGCAATTTTTGATCGGAACCGGAAGGATGAACTGCCTCGGTTGCAACTGGAGTGGATTGATAGCAT
CTGCATGCCTTTGTATCAGGCACTGGTGAAGGTCAACGTGAAACTGAAGCCGATGCTAGATTCAGTAGCTACAAACAGAAGTAAGTGGGA
AGAGCTACACCAAAAACGACTGCTGGCCTCAACTGCCTCATCCTCCCCTGCCAGTGTTATGGTAGCCAAGGAAGACAGGAACTAAACCTC
CAGGTCAGCTGCAGCTGCAAAATGACTACAGCCTGAAGGGCCATTTTCAGTCCAGCAATGTCATCCTTTTGTTCTTTTAGCTCAGAAAGA
CCTAACATCTCAAGGATGCACTGGGAAGCATGCCTGGGCTTTCACCTTGAAGCATGGTCAGCAGCAGAGAGAGCAACGGGAAGGACAAAG
AAAGAGGTGGGGCAGGGAGCACACCCCAGGACCCTCACTTTTCCCTAATGAACACGCATGGGCTGAAATGAAGGCTCTGGGTAGGGGACT
GTTTTGGATCCAAGGACCTGTGGACAGTCGGCCTACTTACTCTGAGCTGAGGGAACACTGAACAGTAAAAGCGTCATTAGCGCTGCTTCG
TTTTGTATAGGGCTTTTCTGTTTGTTACAAGCCAAACACTGCCTGTCTTTGCTTCCTGTCCCTGAATGCCTTTTTGTGCCAGACTGTCCC
AAGAATCCTAATTTGTATTCCATAGAGGTATTTTATTTTTAATCCTAGAGCTTCTTATTGATGGATCCTTTAGAATTGCCTACCTAAAAG
GTAAACTATACTATCCTTATAAATACTGATCAATCCCAGTTCTCCCCCTAAAAATGAATACATAGTAGGACTATAGCAAATGTGTTTGAT
GGGTAATTCTAGACTGGGACTATGGTACCCTTTTCCAGAGTTTTAAAATTCAACCTTCATTACAGACAAAGTTTTCTCCCAGAAGGAATG
GATTGATAGATTTTGATTAAAGTAAGGGTGGAAGGAAATCTGTAGCTGGATTTACCACAAGTGACATCTAGAAACTATAGTTCACAGGAC
AGAGCAGAGCCATGGAGACTAAGCATTGACTACCTTGAGTTCTCCTAGTGAGGAGTTCTGGTATAAAATTTAAGATTACTACCAGTAACC
AACTTAAAGCAAACTATAGGGGTCCCTAATTTTGGATTTTTCCTTAAGTGTAAGAAACAATGCTTCAAATGTTAAGAAATAACAGTCTGG
GCAAAGAACGCATATTCTATAGGAAGCCAGGTTTACAATAGGTAAGAATAAACTGTATTAAGTAGATGTAATGACTAGAAAGCTGCTTTG
CTCCCTATATTGAGAAATTGTGGACATGGTATGTGTTATCCAAAGAACATTGGGCTAGAAGATAGATTTCTATCCTTAGCTTTGGCATTA
TTGACTGGATTGACTTGAACAAGTCACTTAACTTCTACAAGCTTGTTTCCTTATTTGTCAAATTAGATTACACTAGGAAACGATTCTCGA

>4317_4317_8_ANAPC7-PDE11A_ANAPC7_chr12_110832906_ENST00000455511_PDE11A_chr2_178592900_ENST00000358450_length(amino acids)=507AA_BP=170
MDPGDAAILESSLRILYRLFESVLPPLPAALQSRMNVIDHVRDMAAAGLHSNVRLLSSLLLTMSNNNPELFSPPQKYQLLVYHADSLFHD
KEYRNAVSKYTMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILDGIPSRQRTPKAANIPLVSEL
AIDDIHFDDFSLDVDAMITAALRMFMELGMVQKFKIDYETLCRWLLTVRKNYRMVLYHNWRHAFNVCQLMFAMLTTAGFQDILTEVEILA
VIVGCLCHDLDHRGTNNAFQAKSGSALAQLYGTSATLEHHHFNHAVMILQSEGHNIFANLSSKEYSDLMQLLKQSILATDLTLYFERRTE
FFELVSKGEYDWNIKNHRDIFRSMLMTACDLGAVTKPWEISRQVAELVTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSI

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Fusion Gene PPI Analysis for ANAPC7-PDE11A

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for ANAPC7-PDE11A

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for ANAPC7-PDE11A

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source