FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:KPNB1-SLC25A3 (FusionGDB2 ID:43426)

Fusion Gene Summary for KPNB1-SLC25A3

check button Fusion gene summary
Fusion gene informationFusion gene name: KPNB1-SLC25A3
Fusion gene ID: 43426
HgeneTgene
Gene symbol

KPNB1

SLC25A3

Gene ID

3837

5250

Gene namekaryopherin subunit beta 1solute carrier family 25 member 3
SynonymsIMB1|IPO1|IPOB|Impnb|NTF97OK/SW-cl.48|PHC|PTP
Cytomap

17q21.32

12q23.1

Type of geneprotein-codingprotein-coding
Descriptionimportin subunit beta-1PTAC97importin 1importin 90importin beta-1 subunitkaryopherin (importin) beta 1nuclear factor p97pore targeting complex 97 kDa subunitphosphate carrier protein, mitochondrialphosphate transport proteinsolute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
Modification date2020031320200313
UniProtAcc

Q14974

.
Ensembl transtripts involved in fusion geneENST00000577918, ENST00000290158, 
ENST00000535458, ENST00000537679, 
ENST00000540627, 		ENST00000188376, 
ENST00000228318, ENST00000401722, 
ENST00000551917, ENST00000552981, 
ENST00000547534, ENST00000548847, 
ENST00000549338, ENST00000551265, 
Fusion gene scores* DoF score10 X 11 X 5=55012 X 11 X 7=924
# samples 1212
** MAII scorelog2(12/550*10)=-2.1963972128035
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(12/924*10)=-2.94485844580754
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: KPNB1 [Title/Abstract] AND SLC25A3 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointKPNB1(45738544)-SLC25A3(98991633), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneKPNB1

GO:0006606

protein import into nucleus

7615630|15964792

HgeneKPNB1

GO:0006610

ribosomal protein import into nucleus

9687515


check buttonFusion gene breakpoints across KPNB1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SLC25A3 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-61-1917KPNB1chr17

45738544

+SLC25A3chr12

98991633

+


Top

Fusion Gene ORF analysis for KPNB1-SLC25A3

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000577918ENST00000188376KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
3UTR-3CDSENST00000577918ENST00000228318KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
3UTR-3CDSENST00000577918ENST00000401722KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
3UTR-3CDSENST00000577918ENST00000551917KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
3UTR-3CDSENST00000577918ENST00000552981KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
3UTR-intronENST00000577918ENST00000547534KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
3UTR-intronENST00000577918ENST00000548847KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
3UTR-intronENST00000577918ENST00000549338KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
3UTR-intronENST00000577918ENST00000551265KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000290158ENST00000547534KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000290158ENST00000548847KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000290158ENST00000549338KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000290158ENST00000551265KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000535458ENST00000547534KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000535458ENST00000548847KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000535458ENST00000549338KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000535458ENST00000551265KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000537679ENST00000547534KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000537679ENST00000548847KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000537679ENST00000549338KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000537679ENST00000551265KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000540627ENST00000547534KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000540627ENST00000548847KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000540627ENST00000549338KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
5CDS-intronENST00000540627ENST00000551265KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000290158ENST00000188376KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000290158ENST00000228318KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000290158ENST00000401722KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000290158ENST00000551917KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000290158ENST00000552981KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000535458ENST00000188376KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000535458ENST00000228318KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000535458ENST00000401722KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000535458ENST00000551917KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000535458ENST00000552981KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000537679ENST00000188376KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000537679ENST00000228318KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000537679ENST00000401722KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000537679ENST00000551917KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000537679ENST00000552981KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000540627ENST00000188376KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000540627ENST00000228318KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000540627ENST00000401722KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000540627ENST00000551917KPNB1chr17

45738544

+SLC25A3chr12

98991633

+
In-frameENST00000540627ENST00000552981KPNB1chr17

45738544

+SLC25A3chr12

98991633

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000535458KPNB1chr1745738544+ENST00000401722SLC25A3chr1298991633+19859994201805461
ENST00000535458KPNB1chr1745738544+ENST00000228318SLC25A3chr1298991633+22759994201805461
ENST00000535458KPNB1chr1745738544+ENST00000188376SLC25A3chr1298991633+22759994201805461
ENST00000535458KPNB1chr1745738544+ENST00000551917SLC25A3chr1298991633+19859994201805461
ENST00000535458KPNB1chr1745738544+ENST00000552981SLC25A3chr1298991633+19869994201805461
ENST00000290158KPNB1chr1745738544+ENST00000401722SLC25A3chr1298991633+208911034071909500
ENST00000290158KPNB1chr1745738544+ENST00000228318SLC25A3chr1298991633+237911034071909500
ENST00000290158KPNB1chr1745738544+ENST00000188376SLC25A3chr1298991633+237911034071909500
ENST00000290158KPNB1chr1745738544+ENST00000551917SLC25A3chr1298991633+208911034071909500
ENST00000290158KPNB1chr1745738544+ENST00000552981SLC25A3chr1298991633+209011034071909500
ENST00000540627KPNB1chr1745738544+ENST00000401722SLC25A3chr1298991633+17647781631584473
ENST00000540627KPNB1chr1745738544+ENST00000228318SLC25A3chr1298991633+20547781631584473
ENST00000540627KPNB1chr1745738544+ENST00000188376SLC25A3chr1298991633+20547781631584473
ENST00000540627KPNB1chr1745738544+ENST00000551917SLC25A3chr1298991633+17647781631584473
ENST00000540627KPNB1chr1745738544+ENST00000552981SLC25A3chr1298991633+17657781631584473
ENST00000537679KPNB1chr1745738544+ENST00000401722SLC25A3chr1298991633+1335349491155368
ENST00000537679KPNB1chr1745738544+ENST00000228318SLC25A3chr1298991633+1625349491155368
ENST00000537679KPNB1chr1745738544+ENST00000188376SLC25A3chr1298991633+1625349491155368
ENST00000537679KPNB1chr1745738544+ENST00000551917SLC25A3chr1298991633+1335349491155368
ENST00000537679KPNB1chr1745738544+ENST00000552981SLC25A3chr1298991633+1336349491155368

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000535458ENST00000401722KPNB1chr1745738544+SLC25A3chr1298991633+0.0024408670.9975591
ENST00000535458ENST00000228318KPNB1chr1745738544+SLC25A3chr1298991633+0.0013834170.9986166
ENST00000535458ENST00000188376KPNB1chr1745738544+SLC25A3chr1298991633+0.0013834170.9986166
ENST00000535458ENST00000551917KPNB1chr1745738544+SLC25A3chr1298991633+0.0024408670.9975591
ENST00000535458ENST00000552981KPNB1chr1745738544+SLC25A3chr1298991633+0.0024337250.99756634
ENST00000290158ENST00000401722KPNB1chr1745738544+SLC25A3chr1298991633+0.0019738720.9980261
ENST00000290158ENST00000228318KPNB1chr1745738544+SLC25A3chr1298991633+0.0008797820.9991202
ENST00000290158ENST00000188376KPNB1chr1745738544+SLC25A3chr1298991633+0.0008797820.9991202
ENST00000290158ENST00000551917KPNB1chr1745738544+SLC25A3chr1298991633+0.0019738720.9980261
ENST00000290158ENST00000552981KPNB1chr1745738544+SLC25A3chr1298991633+0.0019888450.9980111
ENST00000540627ENST00000401722KPNB1chr1745738544+SLC25A3chr1298991633+0.0024427110.9975573
ENST00000540627ENST00000228318KPNB1chr1745738544+SLC25A3chr1298991633+0.0012135170.9987865
ENST00000540627ENST00000188376KPNB1chr1745738544+SLC25A3chr1298991633+0.0012135170.9987865
ENST00000540627ENST00000551917KPNB1chr1745738544+SLC25A3chr1298991633+0.0024427110.9975573
ENST00000540627ENST00000552981KPNB1chr1745738544+SLC25A3chr1298991633+0.002449820.9975502
ENST00000537679ENST00000401722KPNB1chr1745738544+SLC25A3chr1298991633+0.0022237890.9977762
ENST00000537679ENST00000228318KPNB1chr1745738544+SLC25A3chr1298991633+0.0008240610.99917597
ENST00000537679ENST00000188376KPNB1chr1745738544+SLC25A3chr1298991633+0.0008240610.99917597
ENST00000537679ENST00000551917KPNB1chr1745738544+SLC25A3chr1298991633+0.0022237890.9977762
ENST00000537679ENST00000552981KPNB1chr1745738544+SLC25A3chr1298991633+0.0022302040.99776983

Top

Fusion Genomic Features for KPNB1-SLC25A3


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
KPNB1chr1745738544+SLC25A3chr1298991633+1.93E-060.9999981
KPNB1chr1745738544+SLC25A3chr1298991633+1.93E-060.9999981

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for KPNB1-SLC25A3


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:45738544/chr12:98991633)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
KPNB1

Q14974

.
FUNCTION: Functions in nuclear protein import, either in association with an adapter protein, like an importin-alpha subunit, which binds to nuclear localization signals (NLS) in cargo substrates, or by acting as autonomous nuclear transport receptor. Acting autonomously, serves itself as NLS receptor. Docking of the importin/substrate complex to the nuclear pore complex (NPC) is mediated by KPNB1 through binding to nucleoporin FxFG repeats and the complex is subsequently translocated through the pore by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin-beta and the three components separate and importin-alpha and -beta are re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran from importin. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Mediates autonomously the nuclear import of ribosomal proteins RPL23A, RPS7 and RPL5. Binds to a beta-like import receptor binding (BIB) domain of RPL23A. In association with IPO7 mediates the nuclear import of H1 histone. In vitro, mediates nuclear import of H2A, H2B, H3 and H4 histones. In case of HIV-1 infection, binds and mediates the nuclear import of HIV-1 Rev. Imports SNAI1 and PRKCI into the nucleus. {ECO:0000269|PubMed:10228156, ECO:0000269|PubMed:11891849, ECO:0000269|PubMed:19386897, ECO:0000269|PubMed:24699649, ECO:0000269|PubMed:9687515}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+62221_101232877.0DomainImportin N-terminal
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622129_160232877.0RepeatHEAT 4
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622170_202232877.0RepeatHEAT 5
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+6222_31232877.0RepeatHEAT 1
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+62233_65232877.0RepeatHEAT 2
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+62285_123232877.0RepeatHEAT 3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617160_24493362.0RepeatNote=Solcar 2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617261_33993362.0RepeatNote=Solcar 3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828160_24494363.0RepeatNote=Solcar 2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828261_33994363.0RepeatNote=Solcar 3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228160_24493362.0RepeatNote=Solcar 2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228261_33993362.0RepeatNote=Solcar 3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828160_24493362.0RepeatNote=Solcar 2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828261_33993362.0RepeatNote=Solcar 3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728160_24494363.0RepeatNote=Solcar 2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728261_33994363.0RepeatNote=Solcar 3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128160_24493362.0RepeatNote=Solcar 2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128261_33993362.0RepeatNote=Solcar 3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617142_16193362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617184_21893362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617239_26193362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617285_31493362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617334_36293362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828142_16194363.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828184_21894363.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828239_26194363.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828285_31494363.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828334_36294363.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228142_16193362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228184_21893362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228239_26193362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228285_31493362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228334_36293362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828142_16193362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828184_21893362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828239_26193362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828285_31493362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828334_36293362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728142_16194363.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728184_21894363.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728239_26194363.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728285_31494363.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728334_36294363.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128142_16193362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128184_21893362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128239_26193362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128285_31493362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128334_36293362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617122_14193362.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617162_18393362.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617219_23893362.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617262_28493362.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000018837617315_33393362.0TransmembraneHelical%3B Name%3D6
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828122_14194363.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828162_18394363.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828219_23894363.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828262_28494363.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000022831828315_33394363.0TransmembraneHelical%3B Name%3D6
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228122_14193362.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228162_18393362.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228219_23893362.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228262_28493362.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000040172228315_33393362.0TransmembraneHelical%3B Name%3D6
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828122_14193362.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828162_18393362.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828219_23893362.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828262_28493362.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000054933828315_33393362.0TransmembraneHelical%3B Name%3D6
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728122_14194363.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728162_18394363.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728219_23894363.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728262_28494363.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055191728315_33394363.0TransmembraneHelical%3B Name%3D6
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128122_14193362.0TransmembraneHelical%3B Name%3D2
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128162_18393362.0TransmembraneHelical%3B Name%3D3
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128219_23893362.0TransmembraneHelical%3B Name%3D4
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128262_28493362.0TransmembraneHelical%3B Name%3D5
TgeneSLC25A3chr17:45738544chr12:98991633ENST0000055298128315_33393362.0TransmembraneHelical%3B Name%3D6

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622337_341232877.0Compositional biasNote=Poly-Asp
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622329_342232877.0RegionNote=IAB-binding
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622334_419232877.0RegionNote=Ran-GTP binding
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622212_247232877.0RepeatHEAT 6
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622253_302232877.0RepeatHEAT 7
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622314_360232877.0RepeatHEAT 8
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622364_394232877.0RepeatHEAT 9
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622402_438232877.0RepeatHEAT 10
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622449_485232877.0RepeatHEAT 11
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622500_537232877.0RepeatHEAT 12
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622544_592232877.0RepeatHEAT 13
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622600_639232877.0RepeatHEAT 14
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622644_681232877.0RepeatHEAT 15
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622686_724232877.0RepeatHEAT 16
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622732_776232877.0RepeatHEAT 17
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622786_829232877.0RepeatHEAT 18
HgeneKPNB1chr17:45738544chr12:98991633ENST00000290158+622831_873232877.0RepeatHEAT 19
TgeneSLC25A3chr17:45738544chr12:98991633ENST000001883761763_14793362.0RepeatNote=Solcar 1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000002283182863_14794363.0RepeatNote=Solcar 1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000004017222863_14793362.0RepeatNote=Solcar 1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005493382863_14793362.0RepeatNote=Solcar 1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005519172863_14794363.0RepeatNote=Solcar 1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005529812863_14793362.0RepeatNote=Solcar 1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000001883761750_6393362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST000001883761787_12193362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST000002283182850_6394363.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST000002283182887_12194363.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST000004017222850_6393362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST000004017222887_12193362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005493382850_6393362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005493382887_12193362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005519172850_6394363.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005519172887_12194363.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005529812850_6393362.0Topological domainMitochondrial intermembrane
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005529812887_12193362.0Topological domainMitochondrial matrix
TgeneSLC25A3chr17:45738544chr12:98991633ENST000001883761764_8693362.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000002283182864_8694363.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000004017222864_8693362.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005493382864_8693362.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005519172864_8694363.0TransmembraneHelical%3B Name%3D1
TgeneSLC25A3chr17:45738544chr12:98991633ENST000005529812864_8693362.0TransmembraneHelical%3B Name%3D1


Top

Fusion Gene Sequence for KPNB1-SLC25A3


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>43426_43426_1_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000188376_length(transcript)=2379nt_BP=1103nt
AACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGGTCCGGTCCGAATATCCCTCCGCCTTCCTCCCTCCCTCGCTCCCTCCCTG
CGCGCCGCCTCTCACTCACAGCCTCCCTTCCTTCTTTCTCCCTCCGCCTCCCGAGCACCAGCGCGCTCTGAGCTGCCCCCAGGGTCCCTC
CCCCGCCGCCAGCAGCCCATTTGGAGGGAGGAAGTAAGGGAAGAGGAGAGGAAGGGGAGCCGGACCGACTACCCAGACAGAGCCGGTGAA
TGGGTTTGTGGTGACCCCCGCCCCCCACCCCACCCTCCCTTCCCACCCGACCCCCAACCCCCATCCCCAGTTCGAGCCGCCGCCCGAAAG
GCCGGGCCGTCGTCTTAGGAGGAGTCGCCGCCGCCGCCACCTCCGCCATGGAGCTGATCACCATTCTCGAGAAGACCGTGTCTCCCGATC
GGCTGGAGCTGGAAGCGGCGCAGAAGTTCCTGGAGCGTGCGGCCGTGGAGAACCTGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGG
CAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCAC
AATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACC
GGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGG
CCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGC
AGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTA
CGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAG
CCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTC
GTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCT
TGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTG
ACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAA
TGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCT
GCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACAT
TTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTA
GCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTG
CACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGA
AGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTT
ATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAA
ATAAACCCAACTCTTCATGATTTGCCTGTGACTTATTTTTAAAACTTTTTTAAAAAAGATTTAGCTTTAAAATAGTTGGAAAGAATGAAG
TATATAAGTTAAGGAAAAAATACAAAACTGACCATGACCATTGTTGGTTGAATATTCCAGTTGCTATTCAGAAATTGTCATATGTCTCAA
GTTTTATCACACAAAGTTCCTGTATTTCTAGGGAAGCAGACTTTAAATTTCTAAAAACTTGATTTAATTATAGTTAAATATGTGTAGTCA

>43426_43426_1_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000188376_length(amino acids)=500AA_BP=232
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARRE
VKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG
MRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM
QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAP
LWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVW

--------------------------------------------------------------
>43426_43426_2_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000228318_length(transcript)=2379nt_BP=1103nt
AACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGGTCCGGTCCGAATATCCCTCCGCCTTCCTCCCTCCCTCGCTCCCTCCCTG
CGCGCCGCCTCTCACTCACAGCCTCCCTTCCTTCTTTCTCCCTCCGCCTCCCGAGCACCAGCGCGCTCTGAGCTGCCCCCAGGGTCCCTC
CCCCGCCGCCAGCAGCCCATTTGGAGGGAGGAAGTAAGGGAAGAGGAGAGGAAGGGGAGCCGGACCGACTACCCAGACAGAGCCGGTGAA
TGGGTTTGTGGTGACCCCCGCCCCCCACCCCACCCTCCCTTCCCACCCGACCCCCAACCCCCATCCCCAGTTCGAGCCGCCGCCCGAAAG
GCCGGGCCGTCGTCTTAGGAGGAGTCGCCGCCGCCGCCACCTCCGCCATGGAGCTGATCACCATTCTCGAGAAGACCGTGTCTCCCGATC
GGCTGGAGCTGGAAGCGGCGCAGAAGTTCCTGGAGCGTGCGGCCGTGGAGAACCTGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGG
CAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCAC
AATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACC
GGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGG
CCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGC
AGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTA
CGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAG
CCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTC
GTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCT
TGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTG
ACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAA
TGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCT
GCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACAT
TTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTA
GCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTG
CACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGA
AGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTT
ATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAA
ATAAACCCAACTCTTCATGATTTGCCTGTGACTTATTTTTAAAACTTTTTTAAAAAAGATTTAGCTTTAAAATAGTTGGAAAGAATGAAG
TATATAAGTTAAGGAAAAAATACAAAACTGACCATGACCATTGTTGGTTGAATATTCCAGTTGCTATTCAGAAATTGTCATATGTCTCAA
GTTTTATCACACAAAGTTCCTGTATTTCTAGGGAAGCAGACTTTAAATTTCTAAAAACTTGATTTAATTATAGTTAAATATGTGTAGTCA

>43426_43426_2_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000228318_length(amino acids)=500AA_BP=232
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARRE
VKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG
MRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM
QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAP
LWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVW

--------------------------------------------------------------
>43426_43426_3_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000401722_length(transcript)=2089nt_BP=1103nt
AACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGGTCCGGTCCGAATATCCCTCCGCCTTCCTCCCTCCCTCGCTCCCTCCCTG
CGCGCCGCCTCTCACTCACAGCCTCCCTTCCTTCTTTCTCCCTCCGCCTCCCGAGCACCAGCGCGCTCTGAGCTGCCCCCAGGGTCCCTC
CCCCGCCGCCAGCAGCCCATTTGGAGGGAGGAAGTAAGGGAAGAGGAGAGGAAGGGGAGCCGGACCGACTACCCAGACAGAGCCGGTGAA
TGGGTTTGTGGTGACCCCCGCCCCCCACCCCACCCTCCCTTCCCACCCGACCCCCAACCCCCATCCCCAGTTCGAGCCGCCGCCCGAAAG
GCCGGGCCGTCGTCTTAGGAGGAGTCGCCGCCGCCGCCACCTCCGCCATGGAGCTGATCACCATTCTCGAGAAGACCGTGTCTCCCGATC
GGCTGGAGCTGGAAGCGGCGCAGAAGTTCCTGGAGCGTGCGGCCGTGGAGAACCTGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGG
CAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCAC
AATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACC
GGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGG
CCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGC
AGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTA
CGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAG
CCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTC
GTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCT
TGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTG
ACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAA
TGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCT
GCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACAT
TTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTA
GCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTG
CACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGA
AGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTT
ATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAA

>43426_43426_3_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000401722_length(amino acids)=500AA_BP=232
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARRE
VKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG
MRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM
QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAP
LWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVW

--------------------------------------------------------------
>43426_43426_4_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000551917_length(transcript)=2089nt_BP=1103nt
AACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGGTCCGGTCCGAATATCCCTCCGCCTTCCTCCCTCCCTCGCTCCCTCCCTG
CGCGCCGCCTCTCACTCACAGCCTCCCTTCCTTCTTTCTCCCTCCGCCTCCCGAGCACCAGCGCGCTCTGAGCTGCCCCCAGGGTCCCTC
CCCCGCCGCCAGCAGCCCATTTGGAGGGAGGAAGTAAGGGAAGAGGAGAGGAAGGGGAGCCGGACCGACTACCCAGACAGAGCCGGTGAA
TGGGTTTGTGGTGACCCCCGCCCCCCACCCCACCCTCCCTTCCCACCCGACCCCCAACCCCCATCCCCAGTTCGAGCCGCCGCCCGAAAG
GCCGGGCCGTCGTCTTAGGAGGAGTCGCCGCCGCCGCCACCTCCGCCATGGAGCTGATCACCATTCTCGAGAAGACCGTGTCTCCCGATC
GGCTGGAGCTGGAAGCGGCGCAGAAGTTCCTGGAGCGTGCGGCCGTGGAGAACCTGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGG
CAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCAC
AATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACC
GGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGG
CCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGC
AGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTA
CGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAG
CCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTC
GTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCT
TGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTG
ACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAA
TGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCT
GCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACAT
TTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTA
GCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTG
CACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGA
AGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTT
ATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAA

>43426_43426_4_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000551917_length(amino acids)=500AA_BP=232
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARRE
VKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG
MRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM
QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAP
LWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVW

--------------------------------------------------------------
>43426_43426_5_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000552981_length(transcript)=2090nt_BP=1103nt
AACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGGTCCGGTCCGAATATCCCTCCGCCTTCCTCCCTCCCTCGCTCCCTCCCTG
CGCGCCGCCTCTCACTCACAGCCTCCCTTCCTTCTTTCTCCCTCCGCCTCCCGAGCACCAGCGCGCTCTGAGCTGCCCCCAGGGTCCCTC
CCCCGCCGCCAGCAGCCCATTTGGAGGGAGGAAGTAAGGGAAGAGGAGAGGAAGGGGAGCCGGACCGACTACCCAGACAGAGCCGGTGAA
TGGGTTTGTGGTGACCCCCGCCCCCCACCCCACCCTCCCTTCCCACCCGACCCCCAACCCCCATCCCCAGTTCGAGCCGCCGCCCGAAAG
GCCGGGCCGTCGTCTTAGGAGGAGTCGCCGCCGCCGCCACCTCCGCCATGGAGCTGATCACCATTCTCGAGAAGACCGTGTCTCCCGATC
GGCTGGAGCTGGAAGCGGCGCAGAAGTTCCTGGAGCGTGCGGCCGTGGAGAACCTGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGG
CAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCAC
AATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACC
GGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGG
CCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGC
AGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTA
CGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAG
CCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTC
GTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCT
TGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTG
ACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAA
TGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCT
GCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACAT
TTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTA
GCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTG
CACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGA
AGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTT
ATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAA

>43426_43426_5_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000290158_SLC25A3_chr12_98991633_ENST00000552981_length(amino acids)=500AA_BP=232
MELITILEKTVSPDRLELEAAQKFLERAAVENLPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARRE
VKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQG
MRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSM
QGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAP
LWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVW

--------------------------------------------------------------
>43426_43426_6_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000188376_length(transcript)=2275nt_BP=999nt
GTTGCCGGGCACCTCCCGCCTTCCCGCGCCCCGACCCCGAACTCCTCTCCTTAGTTCTCCCGGGCACCCTATCCTATCAACGCCTACTAT
CCCAGCCAATCGCGCAGGATCCGAGTCGTGCCTCCGGTCCACCCTCCTCCCAGCGCTCAGCCGGTCTGAGCTCAAGGCCTTTACCAAGCC
CACCCAATCAACGGCGGGCTCTCTCCTACCCCATCCCAATCTCCCTCCCCTCGGCCAATCCGCGCGCTCCATTCCGCTGCCCGCCCAGCC
AACCCGGGCCTTGAAACCAGCAGGCGAATGGGCGCGAGACGGCCCTTCGACGCTGAGCGCCTGGCCAGTTAGGGATTCCGCGTGGCCAGG
ACAACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAAC
AGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGG
TGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCC
TCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAAC
CCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAA
TCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTG
AACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCA
GATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAA
GGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATG
CTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCT
CCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAA
GGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACT
GTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTAC
ATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTG
GTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTT
ATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACT
CAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGT
GTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAAATAAACCCAACTCT
TCATGATTTGCCTGTGACTTATTTTTAAAACTTTTTTAAAAAAGATTTAGCTTTAAAATAGTTGGAAAGAATGAAGTATATAAGTTAAGG
AAAAAATACAAAACTGACCATGACCATTGTTGGTTGAATATTCCAGTTGCTATTCAGAAATTGTCATATGTCTCAAGTTTTATCACACAA
AGTTCCTGTATTTCTAGGGAAGCAGACTTTAAATTTCTAAAAACTTGATTTAATTATAGTTAAATATGTGTAGTCATTTGTGGTTATTTT

>43426_43426_6_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000188376_length(amino acids)=461AA_BP=193
MSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPEL
IPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIM
QVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASAS
AEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPE
QLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMP

--------------------------------------------------------------
>43426_43426_7_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000228318_length(transcript)=2275nt_BP=999nt
GTTGCCGGGCACCTCCCGCCTTCCCGCGCCCCGACCCCGAACTCCTCTCCTTAGTTCTCCCGGGCACCCTATCCTATCAACGCCTACTAT
CCCAGCCAATCGCGCAGGATCCGAGTCGTGCCTCCGGTCCACCCTCCTCCCAGCGCTCAGCCGGTCTGAGCTCAAGGCCTTTACCAAGCC
CACCCAATCAACGGCGGGCTCTCTCCTACCCCATCCCAATCTCCCTCCCCTCGGCCAATCCGCGCGCTCCATTCCGCTGCCCGCCCAGCC
AACCCGGGCCTTGAAACCAGCAGGCGAATGGGCGCGAGACGGCCCTTCGACGCTGAGCGCCTGGCCAGTTAGGGATTCCGCGTGGCCAGG
ACAACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAAC
AGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGG
TGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCC
TCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAAC
CCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAA
TCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTG
AACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCA
GATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAA
GGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATG
CTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCT
CCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAA
GGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACT
GTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTAC
ATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTG
GTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTT
ATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACT
CAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGT
GTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAAATAAACCCAACTCT
TCATGATTTGCCTGTGACTTATTTTTAAAACTTTTTTAAAAAAGATTTAGCTTTAAAATAGTTGGAAAGAATGAAGTATATAAGTTAAGG
AAAAAATACAAAACTGACCATGACCATTGTTGGTTGAATATTCCAGTTGCTATTCAGAAATTGTCATATGTCTCAAGTTTTATCACACAA
AGTTCCTGTATTTCTAGGGAAGCAGACTTTAAATTTCTAAAAACTTGATTTAATTATAGTTAAATATGTGTAGTCATTTGTGGTTATTTT

>43426_43426_7_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000228318_length(amino acids)=461AA_BP=193
MSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPEL
IPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIM
QVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASAS
AEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPE
QLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMP

--------------------------------------------------------------
>43426_43426_8_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000401722_length(transcript)=1985nt_BP=999nt
GTTGCCGGGCACCTCCCGCCTTCCCGCGCCCCGACCCCGAACTCCTCTCCTTAGTTCTCCCGGGCACCCTATCCTATCAACGCCTACTAT
CCCAGCCAATCGCGCAGGATCCGAGTCGTGCCTCCGGTCCACCCTCCTCCCAGCGCTCAGCCGGTCTGAGCTCAAGGCCTTTACCAAGCC
CACCCAATCAACGGCGGGCTCTCTCCTACCCCATCCCAATCTCCCTCCCCTCGGCCAATCCGCGCGCTCCATTCCGCTGCCCGCCCAGCC
AACCCGGGCCTTGAAACCAGCAGGCGAATGGGCGCGAGACGGCCCTTCGACGCTGAGCGCCTGGCCAGTTAGGGATTCCGCGTGGCCAGG
ACAACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAAC
AGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGG
TGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCC
TCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAAC
CCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAA
TCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTG
AACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCA
GATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAA
GGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATG
CTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCT
CCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAA
GGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACT
GTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTAC
ATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTG
GTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTT
ATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACT
CAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGT
GTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAAATAAACCCAACTCT

>43426_43426_8_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000401722_length(amino acids)=461AA_BP=193
MSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPEL
IPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIM
QVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASAS
AEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPE
QLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMP

--------------------------------------------------------------
>43426_43426_9_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000551917_length(transcript)=1985nt_BP=999nt
GTTGCCGGGCACCTCCCGCCTTCCCGCGCCCCGACCCCGAACTCCTCTCCTTAGTTCTCCCGGGCACCCTATCCTATCAACGCCTACTAT
CCCAGCCAATCGCGCAGGATCCGAGTCGTGCCTCCGGTCCACCCTCCTCCCAGCGCTCAGCCGGTCTGAGCTCAAGGCCTTTACCAAGCC
CACCCAATCAACGGCGGGCTCTCTCCTACCCCATCCCAATCTCCCTCCCCTCGGCCAATCCGCGCGCTCCATTCCGCTGCCCGCCCAGCC
AACCCGGGCCTTGAAACCAGCAGGCGAATGGGCGCGAGACGGCCCTTCGACGCTGAGCGCCTGGCCAGTTAGGGATTCCGCGTGGCCAGG
ACAACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAAC
AGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGG
TGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCC
TCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAAC
CCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAA
TCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTG
AACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCA
GATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAA
GGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATG
CTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCT
CCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAA
GGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACT
GTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTAC
ATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTG
GTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTT
ATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACT
CAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGT
GTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAAATAAACCCAACTCT

>43426_43426_9_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000551917_length(amino acids)=461AA_BP=193
MSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPEL
IPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIM
QVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASAS
AEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPE
QLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMP

--------------------------------------------------------------
>43426_43426_10_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000552981_length(transcript)=1986nt_BP=999nt
GTTGCCGGGCACCTCCCGCCTTCCCGCGCCCCGACCCCGAACTCCTCTCCTTAGTTCTCCCGGGCACCCTATCCTATCAACGCCTACTAT
CCCAGCCAATCGCGCAGGATCCGAGTCGTGCCTCCGGTCCACCCTCCTCCCAGCGCTCAGCCGGTCTGAGCTCAAGGCCTTTACCAAGCC
CACCCAATCAACGGCGGGCTCTCTCCTACCCCATCCCAATCTCCCTCCCCTCGGCCAATCCGCGCGCTCCATTCCGCTGCCCGCCCAGCC
AACCCGGGCCTTGAAACCAGCAGGCGAATGGGCGCGAGACGGCCCTTCGACGCTGAGCGCCTGGCCAGTTAGGGATTCCGCGTGGCCAGG
ACAACGGCCAATCGTCGTGGAGCGCGGCGCCTCCGCGGAGAGCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAAC
AGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAACTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGG
TGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAACTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCC
TCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAAC
CCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAA
TCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTG
AACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCA
GATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAA
GGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATG
CTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCT
CCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAA
GGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACT
GTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTAC
ATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTG
GTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTT
ATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACT
CAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGT
GTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAAATAAACCCAACTCT

>43426_43426_10_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000535458_SLC25A3_chr12_98991633_ENST00000552981_length(amino acids)=461AA_BP=193
MSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIACAEIPVNQWPEL
IPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIM
QVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASAS
AEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPE
QLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMP

--------------------------------------------------------------
>43426_43426_11_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000188376_length(transcript)=1625nt_BP=349nt
TGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACAT
GAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGC
CATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAA
AGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCA
AAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCT
TGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTA
TCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGT
TCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAA
GGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTT
TGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGC
AATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATT
TAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGT
CTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAA
ATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCT
GATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAAATAAACCCAACTCTTCATGATTTGCCTGTGACTT
ATTTTTAAAACTTTTTTAAAAAAGATTTAGCTTTAAAATAGTTGGAAAGAATGAAGTATATAAGTTAAGGAAAAAATACAAAACTGACCA
TGACCATTGTTGGTTGAATATTCCAGTTGCTATTCAGAAATTGTCATATGTCTCAAGTTTTATCACACAAAGTTCCTGTATTTCTAGGGA
AGCAGACTTTAAATTTCTAAAAACTTGATTTAATTATAGTTAAATATGTGTAGTCATTTGTGGTTATTTTGGCAAGTAAATGTCAGTGTA

>43426_43426_11_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000188376_length(amino acids)=368AA_BP=100
MVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVV
CEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEF
FADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLV
VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESL

--------------------------------------------------------------
>43426_43426_12_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000228318_length(transcript)=1625nt_BP=349nt
TGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACAT
GAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGC
CATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAA
AGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCA
AAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCT
TGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTA
TCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGT
TCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAA
GGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTT
TGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGC
AATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATT
TAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGT
CTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAA
ATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCT
GATATAATTACTGTAGTACTCTTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAAATAAACCCAACTCTTCATGATTTGCCTGTGACTT
ATTTTTAAAACTTTTTTAAAAAAGATTTAGCTTTAAAATAGTTGGAAAGAATGAAGTATATAAGTTAAGGAAAAAATACAAAACTGACCA
TGACCATTGTTGGTTGAATATTCCAGTTGCTATTCAGAAATTGTCATATGTCTCAAGTTTTATCACACAAAGTTCCTGTATTTCTAGGGA
AGCAGACTTTAAATTTCTAAAAACTTGATTTAATTATAGTTAAATATGTGTAGTCATTTGTGGTTATTTTGGCAAGTAAATGTCAGTGTA

>43426_43426_12_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000228318_length(amino acids)=368AA_BP=100
MVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVV
CEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEF
FADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLV
VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESL

--------------------------------------------------------------
>43426_43426_13_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000401722_length(transcript)=1335nt_BP=349nt
TGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACAT
GAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGC
CATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAA
AGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCA
AAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCT
TGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTA
TCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGT
TCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAA
GGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTT
TGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGC
AATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATT
TAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGT
CTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAA
ATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCT

>43426_43426_13_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000401722_length(amino acids)=368AA_BP=100
MVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVV
CEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEF
FADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLV
VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESL

--------------------------------------------------------------
>43426_43426_14_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000551917_length(transcript)=1335nt_BP=349nt
TGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACAT
GAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGC
CATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAA
AGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCA
AAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCT
TGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTA
TCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGT
TCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAA
GGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTT
TGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGC
AATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATT
TAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGT
CTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAA
ATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCT

>43426_43426_14_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000551917_length(amino acids)=368AA_BP=100
MVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVV
CEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEF
FADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLV
VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESL

--------------------------------------------------------------
>43426_43426_15_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000552981_length(transcript)=1336nt_BP=349nt
TGCTTGTGCAGAGATCCCAGTAAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACAT
GAAGGAGTCGACATTGGAAGCCATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGC
CATAATCCAGGGGATGAGGAAAGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAA
AGCAAACTTTGATAAAGAGTCTGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCA
AAAGTACAAGGGCATATTTAACGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCT
TGGCTACTCCATGCAGGGACTCTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTA
TCTCTGGCGCACATCACTATATTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGT
TCGAATTCAAACCCAGCCAGGTTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAA
GGGGGTTGCTCCTCTCTGGATGAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTT
TGTGGTTCCTAAGCCCCGCAGTGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGC
AATTGTTTCTCACCCTGCTGATTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATT
TAAAGGTGTATGGAAGGGACTGTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGT
CTACTTCAGACTTCCTCGCCCTCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAA
ATGTGGACTGAATCTGCTTGTTGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCT

>43426_43426_15_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000537679_SLC25A3_chr12_98991633_ENST00000552981_length(amino acids)=368AA_BP=100
MVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKANFDKESERHFIMQVV
CEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYLWRTSLYLAASASAEF
FADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFVVPKPRSECSKPEQLV
VTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVYFRLPRPPPPEMPESL

--------------------------------------------------------------
>43426_43426_16_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000188376_length(transcript)=2054nt_BP=778nt
ATTTAAGGGGTCCGGAGAAAATGAAGCTAAGTCCGCTAGAGACTGGTCCTTTGTATAAAAATGTGGGATGGATTGGTTGAAACAGCCTAG
ATGCCAGTTAAGTTTCTCTTTGGTGTCCATCTCCTGTTGGGGGATGGGGTCAGAGGGAAGGATTGGATGATGCTTGACATCTTTGAGAAA
GCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAA
CTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAA
CTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGT
AAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGC
CATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAA
AGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTC
TGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAA
CGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACT
CTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATA
TTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGG
TTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGAT
GAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAG
TGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGA
TTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACT
GTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCC
TCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGT
TGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTC
TTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAAATAAACCCAACTCTTCATGATTTGCCTGTGACTTATTTTTAAAACTTTTTTAAAA
AAGATTTAGCTTTAAAATAGTTGGAAAGAATGAAGTATATAAGTTAAGGAAAAAATACAAAACTGACCATGACCATTGTTGGTTGAATAT
TCCAGTTGCTATTCAGAAATTGTCATATGTCTCAAGTTTTATCACACAAAGTTCCTGTATTTCTAGGGAAGCAGACTTTAAATTTCTAAA

>43426_43426_16_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000188376_length(amino acids)=473AA_BP=205
MTSLRKPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIA
CAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKA
NFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYL
WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFV
VPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVY

--------------------------------------------------------------
>43426_43426_17_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000228318_length(transcript)=2054nt_BP=778nt
ATTTAAGGGGTCCGGAGAAAATGAAGCTAAGTCCGCTAGAGACTGGTCCTTTGTATAAAAATGTGGGATGGATTGGTTGAAACAGCCTAG
ATGCCAGTTAAGTTTCTCTTTGGTGTCCATCTCCTGTTGGGGGATGGGGTCAGAGGGAAGGATTGGATGATGCTTGACATCTTTGAGAAA
GCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAA
CTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAA
CTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGT
AAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGC
CATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAA
AGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTC
TGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAA
CGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACT
CTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATA
TTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGG
TTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGAT
GAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAG
TGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGA
TTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACT
GTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCC
TCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGT
TGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTC
TTGCTTAAGGCAAGAGTTTCAGATTTACTGTTGAAATAAACCCAACTCTTCATGATTTGCCTGTGACTTATTTTTAAAACTTTTTTAAAA
AAGATTTAGCTTTAAAATAGTTGGAAAGAATGAAGTATATAAGTTAAGGAAAAAATACAAAACTGACCATGACCATTGTTGGTTGAATAT
TCCAGTTGCTATTCAGAAATTGTCATATGTCTCAAGTTTTATCACACAAAGTTCCTGTATTTCTAGGGAAGCAGACTTTAAATTTCTAAA

>43426_43426_17_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000228318_length(amino acids)=473AA_BP=205
MTSLRKPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIA
CAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKA
NFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYL
WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFV
VPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVY

--------------------------------------------------------------
>43426_43426_18_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000401722_length(transcript)=1764nt_BP=778nt
ATTTAAGGGGTCCGGAGAAAATGAAGCTAAGTCCGCTAGAGACTGGTCCTTTGTATAAAAATGTGGGATGGATTGGTTGAAACAGCCTAG
ATGCCAGTTAAGTTTCTCTTTGGTGTCCATCTCCTGTTGGGGGATGGGGTCAGAGGGAAGGATTGGATGATGCTTGACATCTTTGAGAAA
GCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAA
CTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAA
CTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGT
AAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGC
CATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAA
AGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTC
TGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAA
CGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACT
CTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATA
TTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGG
TTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGAT
GAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAG
TGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGA
TTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACT
GTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCC
TCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGT
TGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTC

>43426_43426_18_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000401722_length(amino acids)=473AA_BP=205
MTSLRKPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIA
CAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKA
NFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYL
WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFV
VPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVY

--------------------------------------------------------------
>43426_43426_19_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000551917_length(transcript)=1764nt_BP=778nt
ATTTAAGGGGTCCGGAGAAAATGAAGCTAAGTCCGCTAGAGACTGGTCCTTTGTATAAAAATGTGGGATGGATTGGTTGAAACAGCCTAG
ATGCCAGTTAAGTTTCTCTTTGGTGTCCATCTCCTGTTGGGGGATGGGGTCAGAGGGAAGGATTGGATGATGCTTGACATCTTTGAGAAA
GCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAA
CTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAA
CTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGT
AAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGC
CATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAA
AGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTC
TGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAA
CGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACT
CTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATA
TTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGG
TTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGAT
GAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAG
TGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGA
TTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACT
GTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCC
TCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGT
TGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTC

>43426_43426_19_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000551917_length(amino acids)=473AA_BP=205
MTSLRKPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIA
CAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKA
NFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYL
WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFV
VPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVY

--------------------------------------------------------------
>43426_43426_20_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000552981_length(transcript)=1765nt_BP=778nt
ATTTAAGGGGTCCGGAGAAAATGAAGCTAAGTCCGCTAGAGACTGGTCCTTTGTATAAAAATGTGGGATGGATTGGTTGAAACAGCCTAG
ATGCCAGTTAAGTTTCTCTTTGGTGTCCATCTCCTGTTGGGGGATGGGGTCAGAGGGAAGGATTGGATGATGCTTGACATCTTTGAGAAA
GCCCACTTTCCTTGTGGAACTGTCCAGAGTGCTGGCAAATCCAGGAAACAGTCAGGTTGCCAGAGTTGCAGCTGGTCTACAAATCAAGAA
CTCTTTGACATCTAAAGATCCAGATATCAAGGCACAATATCAGCAGAGGTGGCTTGCTATTGATGCTAATGCTCGACGAGAAGTCAAGAA
CTATGTTTTGCAGACATTGGGTACAGAAACTTACCGGCCTAGTTCTGCCTCACAGTGTGTGGCTGGTATTGCTTGTGCAGAGATCCCAGT
AAACCAGTGGCCAGAACTCATTCCTCAGCTGGTGGCCAATGTCACAAACCCCAACAGCACAGAGCACATGAAGGAGTCGACATTGGAAGC
CATCGGTTATATTTGCCAAGATATAGACCCAGAGCAGCTACAAGATAAATCCAATGAGATTCTGACTGCCATAATCCAGGGGATGAGGAA
AGAAGAGCCTAGTAATAATGTGAAGCTAGCTGCTACGAATGCACTCCTGAACTCATTGGAGTTCACCAAAGCAAACTTTGATAAAGAGTC
TGAAAGGCACTTTATTATGCAGGTGGTCTGTGAAGCCACACAGTGTCCAGATACGAGGGTGGACCCCCAAAAGTACAAGGGCATATTTAA
CGGATTCTCAGTTACACTTAAAGAGGATGGTGTTCGTGGTTTGGCTAAAGGATGGGCTCCGACTTTCCTTGGCTACTCCATGCAGGGACT
CTGCAAGTTTGGCTTTTATGAAGTCTTTAAAGTCTTGTATAGCAATATGCTTGGAGAGGAGAATACTTATCTCTGGCGCACATCACTATA
TTTGGCTGCCTCTGCCAGTGCTGAATTCTTTGCTGACATTGCCCTGGCTCCTATGGAAGCTGCTAAGGTTCGAATTCAAACCCAGCCAGG
TTATGCCAACACTTTGAGGGATGCAGCTCCCAAAATGTATAAGGAAGAAGGCCTAAAAGCATTCTACAAGGGGGTTGCTCCTCTCTGGAT
GAGACAGATACCATACACCATGATGAAGTTCGCCTGCTTTGAACGTACTGTTGAAGCACTGTACAAGTTTGTGGTTCCTAAGCCCCGCAG
TGAATGTTCAAAGCCAGAGCAGCTGGTTGTAACATTTGTAGCAGGTTACATAGCTGGAGTCTTTTGTGCAATTGTTTCTCACCCTGCTGA
TTCTGTGGTATCTGTGTTGAATAAAGAAAAAGGTAGCAGTGCTTCTCTGGTCCTCAAGAGACTTGGATTTAAAGGTGTATGGAAGGGACT
GTTTGCCCGTATCATCATGATTGGTACCCTGACTGCACTACAGTGGTTTATCTATGACTCCGTGAAGGTCTACTTCAGACTTCCTCGCCC
TCCTCCACCCGAGATGCCAGAGTCTCTGAAGAAGAAGCTTGGGTTAACTCAGTAGTTAGATCAAAGCAAATGTGGACTGAATCTGCTTGT
TGATCAGTGTTGAAGAAAGTGCAAAAGGAACTTTTATATATTTGACAGTGTAGGAAATTGTCTATTCCTGATATAATTACTGTAGTACTC

>43426_43426_20_KPNB1-SLC25A3_KPNB1_chr17_45738544_ENST00000540627_SLC25A3_chr12_98991633_ENST00000552981_length(amino acids)=473AA_BP=205
MTSLRKPTFLVELSRVLANPGNSQVARVAAGLQIKNSLTSKDPDIKAQYQQRWLAIDANARREVKNYVLQTLGTETYRPSSASQCVAGIA
CAEIPVNQWPELIPQLVANVTNPNSTEHMKESTLEAIGYICQDIDPEQLQDKSNEILTAIIQGMRKEEPSNNVKLAATNALLNSLEFTKA
NFDKESERHFIMQVVCEATQCPDTRVDPQKYKGIFNGFSVTLKEDGVRGLAKGWAPTFLGYSMQGLCKFGFYEVFKVLYSNMLGEENTYL
WRTSLYLAASASAEFFADIALAPMEAAKVRIQTQPGYANTLRDAAPKMYKEEGLKAFYKGVAPLWMRQIPYTMMKFACFERTVEALYKFV
VPKPRSECSKPEQLVVTFVAGYIAGVFCAIVSHPADSVVSVLNKEKGSSASLVLKRLGFKGVWKGLFARIIMIGTLTALQWFIYDSVKVY

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for KPNB1-SLC25A3


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for KPNB1-SLC25A3


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for KPNB1-SLC25A3


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource