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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
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Fusion gene:KRAS-SLC2A14 (FusionGDB2 ID:43436)

Fusion Gene Summary for KRAS-SLC2A14

Fusion gene summary

Fusion gene information	Fusion gene name: KRAS-SLC2A14
	Fusion gene ID: 43436
		Hgene	Tgene
	Gene symbol	KRAS	SLC2A14
	Gene ID	3845	144195
	Gene name	KRAS proto-oncogene, GTPase	solute carrier family 2 member 14
	Synonyms	'C-K-RAS\|C-K-RAS\|CFC2\|K-RAS2A\|K-RAS2B\|K-RAS4A\|K-RAS4B\|K-Ras\|K-Ras 2\|KI-RAS\|KRAS1\|KRAS2\|NS\|NS3\|OES\|RALD\|RASK2\|c-Ki-ras\|c-Ki-ras2	GLUT14\|SLC2A3P3
	Cytomap	12p12.1	12p13.31
	Type of gene	protein-coding	protein-coding
	Description	GTPase KRasK-ras p21 proteinKirsten rat sarcoma viral oncogene homologKirsten rat sarcoma viral proto-oncogenePR310 c-K-ras oncogenec-Kirsten-ras proteincellular c-Ki-ras2 proto-oncogenecellular transforming proto-oncogeneoncogene KRAS2transformi	solute carrier family 2, facilitated glucose transporter member 14glucose transporter type 14solute carrier family 2 (facilitated glucose transporter), member 14solute carrier family 2 (facilitated glucose transporter), member 3 pseudogene 3
	Modification date	20200329	20200313
	UniProtAcc	P01116	.
	Ensembl transtripts involved in fusion gene	ENST00000256078, ENST00000311936, ENST00000556131, ENST00000557334,	ENST00000535295, ENST00000539924, ENST00000542546, ENST00000396589, ENST00000542505, ENST00000544749, ENST00000340749, ENST00000431042, ENST00000543909,
Fusion gene scores	* DoF score	6 X 2 X 5=60	6 X 5 X 4=120
	# samples	6	6
	** MAII score	log2(6/60*10)=0	log2(6/120*10)=-1 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: KRAS [Title/Abstract] AND SLC2A14 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	KRAS(25398208)-SLC2A14(7985410), # samples:1
Anticipated loss of major functional domain due to fusion event.	KRAS-SLC2A14 seems lost the major protein functional domain in Hgene partner, which is a CGC due to the frame-shifted ORF. KRAS-SLC2A14 seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. KRAS-SLC2A14 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. KRAS-SLC2A14 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Tgene	SLC2A14	GO:0070837	dehydroascorbic acid transport	28971850
Tgene	SLC2A14	GO:1904659	glucose transmembrane transport	28971850

Fusion gene breakpoints across KRAS (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across SLC2A14 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	LUAD	TCGA-75-5122-01A	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-

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Fusion Gene ORF analysis for KRAS-SLC2A14

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000256078	ENST00000535295	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000256078	ENST00000539924	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000256078	ENST00000542546	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000311936	ENST00000535295	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000311936	ENST00000539924	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000311936	ENST00000542546	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000556131	ENST00000535295	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000556131	ENST00000539924	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000556131	ENST00000542546	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000557334	ENST00000535295	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000557334	ENST00000539924	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-5UTR	ENST00000557334	ENST00000542546	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000256078	ENST00000396589	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000256078	ENST00000542505	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000256078	ENST00000544749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000311936	ENST00000396589	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000311936	ENST00000542505	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000311936	ENST00000544749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000556131	ENST00000396589	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000556131	ENST00000542505	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000556131	ENST00000544749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000557334	ENST00000396589	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000557334	ENST00000542505	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
5CDS-intron	ENST00000557334	ENST00000544749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
Frame-shift	ENST00000556131	ENST00000340749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
Frame-shift	ENST00000556131	ENST00000431042	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
Frame-shift	ENST00000556131	ENST00000543909	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
In-frame	ENST00000256078	ENST00000340749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
In-frame	ENST00000256078	ENST00000431042	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
In-frame	ENST00000256078	ENST00000543909	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
In-frame	ENST00000311936	ENST00000340749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
In-frame	ENST00000311936	ENST00000431042	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
In-frame	ENST00000311936	ENST00000543909	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
In-frame	ENST00000557334	ENST00000340749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
In-frame	ENST00000557334	ENST00000431042	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-
In-frame	ENST00000557334	ENST00000543909	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000311936	KRAS	chr12	25398208	-	ENST00000340749	SLC2A14	chr12	7985410	-	3583	303	183	1778	531
ENST00000311936	KRAS	chr12	25398208	-	ENST00000543909	SLC2A14	chr12	7985410	-	3581	303	183	1778	531
ENST00000311936	KRAS	chr12	25398208	-	ENST00000431042	SLC2A14	chr12	7985410	-	3576	303	183	1778	531
ENST00000557334	KRAS	chr12	25398208	-	ENST00000340749	SLC2A14	chr12	7985410	-	3588	308	188	1783	531
ENST00000557334	KRAS	chr12	25398208	-	ENST00000543909	SLC2A14	chr12	7985410	-	3586	308	188	1783	531
ENST00000557334	KRAS	chr12	25398208	-	ENST00000431042	SLC2A14	chr12	7985410	-	3581	308	188	1783	531
ENST00000256078	KRAS	chr12	25398208	-	ENST00000340749	SLC2A14	chr12	7985410	-	3455	175	55	1650	531
ENST00000256078	KRAS	chr12	25398208	-	ENST00000543909	SLC2A14	chr12	7985410	-	3453	175	55	1650	531
ENST00000256078	KRAS	chr12	25398208	-	ENST00000431042	SLC2A14	chr12	7985410	-	3448	175	55	1650	531

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000311936	ENST00000340749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-	0.000498595	0.99950135
ENST00000311936	ENST00000543909	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-	0.000502041	0.9994979
ENST00000311936	ENST00000431042	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-	0.000511507	0.9994885
ENST00000557334	ENST00000340749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-	0.00049765	0.9995023
ENST00000557334	ENST00000543909	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-	0.000501085	0.99949884
ENST00000557334	ENST00000431042	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-	0.000510517	0.9994894
ENST00000256078	ENST00000340749	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-	0.000420406	0.9995796
ENST00000256078	ENST00000543909	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-	0.000422263	0.9995777
ENST00000256078	ENST00000431042	KRAS	chr12	25398208	-	SLC2A14	chr12	7985410	-	0.00043032	0.9995697

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Fusion Genomic Features for KRAS-SLC2A14

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for KRAS-SLC2A14

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:25398208/chr12:7985410)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
KRAS P01116	.
FUNCTION: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621). Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838). Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306). {ECO:0000269\|PubMed:20949621, ECO:0000269\|PubMed:22711838, ECO:0000269\|PubMed:23698361, ECO:0000269\|PubMed:24623306, ECO:0000305}.	FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000256078

32_40

333.3333333333333

Motif

Note=Effector region

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000311936

32_40

189.0

Motif

Note=Effector region

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000256078

10_18

333.3333333333333

Nucleotide binding

GTP

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000256078

29_35

333.3333333333333

Nucleotide binding

GTP

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000311936

10_18

189.0

Nucleotide binding

GTP

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000311936

29_35

189.0

Nucleotide binding

GTP

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

304_310

498.0

Region

Monosaccharide binding

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

304_310

521.0

Region

Monosaccharide binding

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

304_310

498.0

Region

Monosaccharide binding

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

304_310

162.0

Region

Monosaccharide binding

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

304_310

521.0

Region

Monosaccharide binding

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

110_117

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

139_148

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

170_177

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

199_207

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

229_293

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

315_328

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

350_358

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

380_392

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

414_423

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

445_451

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

473_520

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

51_88

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

110_117

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

139_148

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

170_177

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

199_207

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

229_293

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

315_328

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

350_358

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

380_392

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

414_423

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

445_451

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

473_520

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

51_88

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

110_117

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

139_148

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

170_177

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

199_207

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

229_293

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

315_328

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

350_358

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

380_392

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

414_423

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

445_451

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

473_520

498.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

51_88

498.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

110_117

162.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

139_148

162.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

170_177

162.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

199_207

162.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

229_293

162.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

315_328

162.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

350_358

162.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

380_392

162.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

414_423

162.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

445_451

162.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

473_520

162.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

51_88

162.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

110_117

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

139_148

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

170_177

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

199_207

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

229_293

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

315_328

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

350_358

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

380_392

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

414_423

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

445_451

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

473_520

521.0

Topological domain

Cytoplasmic

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

51_88

521.0

Topological domain

Extracellular

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

118_138

498.0

Transmembrane

Helical%3B Name%3D3

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

149_169

498.0

Transmembrane

Helical%3B Name%3D4

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

178_198

498.0

Transmembrane

Helical%3B Name%3D5

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

208_228

498.0

Transmembrane

Helical%3B Name%3D6

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

294_314

498.0

Transmembrane

Helical%3B Name%3D7

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

30_50

498.0

Transmembrane

Helical%3B Name%3D1

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

329_349

498.0

Transmembrane

Helical%3B Name%3D8

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

359_379

498.0

Transmembrane

Helical%3B Name%3D9

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

393_413

498.0

Transmembrane

Helical%3B Name%3D10

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

424_444

498.0

Transmembrane

Helical%3B Name%3D11

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

452_472

498.0

Transmembrane

Helical%3B Name%3D12

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000340749

89_109

498.0

Transmembrane

Helical%3B Name%3D2

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

118_138

521.0

Transmembrane

Helical%3B Name%3D3

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

149_169

521.0

Transmembrane

Helical%3B Name%3D4

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

178_198

521.0

Transmembrane

Helical%3B Name%3D5

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

208_228

521.0

Transmembrane

Helical%3B Name%3D6

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

294_314

521.0

Transmembrane

Helical%3B Name%3D7

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

30_50

521.0

Transmembrane

Helical%3B Name%3D1

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

329_349

521.0

Transmembrane

Helical%3B Name%3D8

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

359_379

521.0

Transmembrane

Helical%3B Name%3D9

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

393_413

521.0

Transmembrane

Helical%3B Name%3D10

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

424_444

521.0

Transmembrane

Helical%3B Name%3D11

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

452_472

521.0

Transmembrane

Helical%3B Name%3D12

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000396589

89_109

521.0

Transmembrane

Helical%3B Name%3D2

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

118_138

498.0

Transmembrane

Helical%3B Name%3D3

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

149_169

498.0

Transmembrane

Helical%3B Name%3D4

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

178_198

498.0

Transmembrane

Helical%3B Name%3D5

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

208_228

498.0

Transmembrane

Helical%3B Name%3D6

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

294_314

498.0

Transmembrane

Helical%3B Name%3D7

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

30_50

498.0

Transmembrane

Helical%3B Name%3D1

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

329_349

498.0

Transmembrane

Helical%3B Name%3D8

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

359_379

498.0

Transmembrane

Helical%3B Name%3D9

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

393_413

498.0

Transmembrane

Helical%3B Name%3D10

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

424_444

498.0

Transmembrane

Helical%3B Name%3D11

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

452_472

498.0

Transmembrane

Helical%3B Name%3D12

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000431042

89_109

498.0

Transmembrane

Helical%3B Name%3D2

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

118_138

162.0

Transmembrane

Helical%3B Name%3D3

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

149_169

162.0

Transmembrane

Helical%3B Name%3D4

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

178_198

162.0

Transmembrane

Helical%3B Name%3D5

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

208_228

162.0

Transmembrane

Helical%3B Name%3D6

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

294_314

162.0

Transmembrane

Helical%3B Name%3D7

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

30_50

162.0

Transmembrane

Helical%3B Name%3D1

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

329_349

162.0

Transmembrane

Helical%3B Name%3D8

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

359_379

162.0

Transmembrane

Helical%3B Name%3D9

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

393_413

162.0

Transmembrane

Helical%3B Name%3D10

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

424_444

162.0

Transmembrane

Helical%3B Name%3D11

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

452_472

162.0

Transmembrane

Helical%3B Name%3D12

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000542505

89_109

162.0

Transmembrane

Helical%3B Name%3D2

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

118_138

521.0

Transmembrane

Helical%3B Name%3D3

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

149_169

521.0

Transmembrane

Helical%3B Name%3D4

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

178_198

521.0

Transmembrane

Helical%3B Name%3D5

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

208_228

521.0

Transmembrane

Helical%3B Name%3D6

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

294_314

521.0

Transmembrane

Helical%3B Name%3D7

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

30_50

521.0

Transmembrane

Helical%3B Name%3D1

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

329_349

521.0

Transmembrane

Helical%3B Name%3D8

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

359_379

521.0

Transmembrane

Helical%3B Name%3D9

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

393_413

521.0

Transmembrane

Helical%3B Name%3D10

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

424_444

521.0

Transmembrane

Helical%3B Name%3D11

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

452_472

521.0

Transmembrane

Helical%3B Name%3D12

Tgene

SLC2A14

chr12:25398208

chr12:7985410

ENST00000543909

89_109

521.0

Transmembrane

Helical%3B Name%3D2

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000256078

116_119

333.3333333333333

Nucleotide binding

GTP

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000256078

59_60

333.3333333333333

Nucleotide binding

GTP

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000311936

116_119

189.0

Nucleotide binding

GTP

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000311936

59_60

189.0

Nucleotide binding

GTP

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000256078

166_185

333.3333333333333

Region

Note=Hypervariable region

Hgene

KRAS

chr12:25398208

chr12:7985410

ENST00000311936

166_185

189.0

Region

Note=Hypervariable region

Top

Fusion Gene Sequence for KRAS-SLC2A14

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>43436_43436_1_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000256078_SLC2A14_chr12_7985410_ENST00000340749_length(transcript)=3455nt_BP=175nt
CTGAAGGCGGCGGCGGGGCCAGAGGCTCAGCGGCTCCCAGGTGCGGGAGAGAGGCCTGCTGAAAATGACTGAATATAAACTTGTGGTAGT
TGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTCAGAATCATTTTGTGGACGAATATGATCCAACAATAGAGGTCAC
CCCAGCTCTGATCTTTGCCATCACAGTTGCTACAATCGGCTCTTTCCAGTTTGGCTACAACACTGGGGTCATCAATGCTCCTGAGACGAT
CATAAAGGAATTTATCAATAAAACTTTGACGGACAAGGCAAATGCCCCTCCCTCTGAGGTGCTGCTCACGAATCTCTGGTCCTTGTCTGT
GGCCATATTTTCCGTCGGGGGTATGATCGGCTCCTTTTCCGTCGGACTCTTTGTTAACCGCTTTGGCAGGCGCAATTCAATGCTGATTGT
CAACCTGTTGGCTGCCACTGGTGGCTGCCTTATGGGACTGTGTAAAATAGCTGAGTCAGTTGAAATGCTGATCCTGGGCCGCTTGGTTAT
TGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCCCATGTACATTGGAGAGATCTCGCCTACTGCCCTGAGGGGTGCCTTTGGCACTCT
CAACCAGCTGGGCATAGTTATTGGAATTCTGGTGGCCCAGATCTTTGGTCTGGAACTCATCCTTGGGTCTGAAGAGCTATGGCCGGTGCT
ATTAGGCTTTACCATCCTTCCAGCTATCCTGCAAAGTGCAGCCCTTCCATGTTGCCCTGAAAGTCCCAGATTTTTGCTCATTAACAGAAA
AAAAGAGGAGAATGCTACGCGGATCCTCCAGCGGTTGTGGGGCACCCAGGATGTATCCCAAGACATCCAGGAGATGAAAGATGAGAGTGC
AAGGATGTCACAAGAAAAGCAAGTCACCGTGCTGGAGCTCTTTAGAGTGTCCAGCTACCGACAGCCCATCATCATTTCCATTGTGCTCCA
GCTCTCTCAGCAGCTCTCTGGGATCAATGCTGTGTTCTATTACTCAACAGGAATCTTCAAGGATGCAGGTGTTCAACAGCCCATCTATGC
CACCATCAGCGCGGGTGTGGTTAATACTATCTTCACTTTACTTTCTCTATTTCTGGTGGAAAGGGCAGGAAGAAGGACTCTGCATATGAT
AGGCCTTGGAGGGATGGCTTTTTGTTCCACGCTCATGACTGTTTCTTTGTTATTAAAGAATCACTATAATGGGATGAGCTTTGTCTGTAT
TGGGGCTATCTTGGTCTTTGTGGCCTGTTTTGAAATTGGACCAGGCCCCATTCCCTGGTTTATTGTGGCCGAACTCTTCAGCCAGGGCCC
CCGCCCAGCTGCGATGGCAGTGGCCGGCTGCTCCAACTGGACCTCCAACTTCCTAGTCGGATTGCTCTTCCCCTCTGCTGCTTACTATTT
AGGAGCCTACGTTTTTATTATCTTCACCGGCTTCCTCATTACCTTCTTGGCCTTTACCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGAC
TTTTGAGGATATCACACGGGCCTTTGAAGGGCAGGCACACGGTGCAGATAGATCTGGGAAGGACGGCGTCATGGGGATGAACAGCATCGA
GCCTGCTAAGGAGACCACCACCAATGTCTAAGTCATGCCTCCTTCCACCTCCCTCCCGGCATGGGAAAGCCACCTCTCCCTCAACAAGGG
AGAGACTTTATCAGGATGAACCCAGGACTGCTTCTGAATGCTGCTACTTGATTTCTTTCTCATCCCACGCACTCCATGAGCACCCCAAGG
CTGCAGTTTGTTGGATCTTCAATGGCTTTTTAAATTTTATTTCCTGGACATCCTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCA
TTTCAGGAGGGATTGGCCGCTTGGCACATGACAACTTTGCCAGCTTTTCCTCCCTTGGGTTCTGATATTGCCGCACTAGAGGATATAGGA
GAGGAAAAGTAAGGTGCAGTTGCCCCAACCTCAGACTTACCAGGAAGCAGATACATATGAGTGTGGAAGCCGGAGGGTGTTTATGTAAGA
GCACCTTCCTCACTTCCATACAGCTCTACGCGGCAAATTAACTTGAGTTTTATTTATCTTATCCTCTGGTTTAATTACATAAATATTTAT
TTTTTAAGTGTAATTTTGCCAAATAATAAAAACAGAAGGAAATTGAGATTAGAGGGAGGTGTTTAAAGAGAGGTTATAGAGTAAAAGATT
TGATGCTGGAGAGGTTAAGGTGCAATAAGAATTCAGGGAGAAATGTTGTTCATTATTGGAGGGTAAATGATGTGGTGCCTGAGGTCTGTA
CATTACCTCTTAACAATTTCTGTCCTTCAGATGGAAACTCTTTGATTTCTCAGAAAAGTTGTATGCCTATTTAATAAAGCTACTCATTTC
CTTTGGAACTTTATCTTTAAGATAATAGTTTACATGTAGTAGTACTTGAAATCTAGGATTATTAACTAATATGGGCATTGTAGTTAATGG
CGGTTGATGGGTTCTAATTTTGGATGGAGTCCAGGGAAGAGAAAGTGATTTCTAGAAAGCCTGTTCCCCTCACTGGACGAAATAACTCCT
TGTAGTAGTCTCATTACTTTTGAAGTAATCCCGCCACCTATCTAGTGGGAGAGCCATCCAAATGAGAAACCTAAAATAATTGGTTCTTGG
TAGAGATTCATTATTTCTCCACTTTGTTCTTTAGGAGATTTTAGGTGTTGATTTTCTGTTTTATTTTAACTCATACCTTTAAAGGAATTC
CCCAAAGAATGTTTACAGCAAACTTGGAATTTGTAACCTCAGCTCTGGGAGAGGATTTTTTTCTGAGCGATTATTATCTAAAGTGTGTTG
TTGCTTTAGGCTCACGGCACGCTTGCGTATGTCTGTTACCATGTCACTGTGGTCCTATGCCGAATGCCCTCAGGGGACTTGAATCTTTCC
AATAAACCAGGTTTAGACAGTATGAGTCAATGTGCAGTGCAGCCCACACTTGAGAGGATGAATGTATGTGCACTGTCACTTTGCTCTGGG
TGGAAGTATGTTATTGTTGACTTATTTTCTCTGTGTTTGTTCCTACAGCCCCTTTTTCATATGTTGCTCAGTCTCCCTTTCCCTTCTTGG
TGCTTACACATCTCAGACCCTTTAGCCAAACCCTTGCCAGTGACAGTATTTTGGTTCTCAGTTCTCACTGTTCCCTCTGCTCCTGGAGCC
TTTGAATAAAAATGCACGTAGCTATGGAGTGGGGTTTAGCTGGAAAGGTGGCCTTCCAACTTCACGTCAACTTCTGGCTCCTCAGTTTGG
CAGTAAGGCAGGGAAGTTGTTTTCCTATTTCTCACTGAGAAGATTGTGAATATTTCCATATGGATTTTCCATTATTGTTTGTTTGATTCT

>43436_43436_1_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000256078_SLC2A14_chr12_7985410_ENST00000340749_length(amino acids)=531AA_BP=40
MLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPS
EVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI
SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV
SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL
VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL

--------------------------------------------------------------
>43436_43436_2_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000256078_SLC2A14_chr12_7985410_ENST00000431042_length(transcript)=3448nt_BP=175nt
CTGAAGGCGGCGGCGGGGCCAGAGGCTCAGCGGCTCCCAGGTGCGGGAGAGAGGCCTGCTGAAAATGACTGAATATAAACTTGTGGTAGT
TGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTCAGAATCATTTTGTGGACGAATATGATCCAACAATAGAGGTCAC
CCCAGCTCTGATCTTTGCCATCACAGTTGCTACAATCGGCTCTTTCCAGTTTGGCTACAACACTGGGGTCATCAATGCTCCTGAGACGAT
CATAAAGGAATTTATCAATAAAACTTTGACGGACAAGGCAAATGCCCCTCCCTCTGAGGTGCTGCTCACGAATCTCTGGTCCTTGTCTGT
GGCCATATTTTCCGTCGGGGGTATGATCGGCTCCTTTTCCGTCGGACTCTTTGTTAACCGCTTTGGCAGGCGCAATTCAATGCTGATTGT
CAACCTGTTGGCTGCCACTGGTGGCTGCCTTATGGGACTGTGTAAAATAGCTGAGTCAGTTGAAATGCTGATCCTGGGCCGCTTGGTTAT
TGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCCCATGTACATTGGAGAGATCTCGCCTACTGCCCTGAGGGGTGCCTTTGGCACTCT
CAACCAGCTGGGCATAGTTATTGGAATTCTGGTGGCCCAGATCTTTGGTCTGGAACTCATCCTTGGGTCTGAAGAGCTATGGCCGGTGCT
ATTAGGCTTTACCATCCTTCCAGCTATCCTGCAAAGTGCAGCCCTTCCATGTTGCCCTGAAAGTCCCAGATTTTTGCTCATTAACAGAAA
AAAAGAGGAGAATGCTACGCGGATCCTCCAGCGGTTGTGGGGCACCCAGGATGTATCCCAAGACATCCAGGAGATGAAAGATGAGAGTGC
AAGGATGTCACAAGAAAAGCAAGTCACCGTGCTGGAGCTCTTTAGAGTGTCCAGCTACCGACAGCCCATCATCATTTCCATTGTGCTCCA
GCTCTCTCAGCAGCTCTCTGGGATCAATGCTGTGTTCTATTACTCAACAGGAATCTTCAAGGATGCAGGTGTTCAACAGCCCATCTATGC
CACCATCAGCGCGGGTGTGGTTAATACTATCTTCACTTTACTTTCTCTATTTCTGGTGGAAAGGGCAGGAAGAAGGACTCTGCATATGAT
AGGCCTTGGAGGGATGGCTTTTTGTTCCACGCTCATGACTGTTTCTTTGTTATTAAAGAATCACTATAATGGGATGAGCTTTGTCTGTAT
TGGGGCTATCTTGGTCTTTGTGGCCTGTTTTGAAATTGGACCAGGCCCCATTCCCTGGTTTATTGTGGCCGAACTCTTCAGCCAGGGCCC
CCGCCCAGCTGCGATGGCAGTGGCCGGCTGCTCCAACTGGACCTCCAACTTCCTAGTCGGATTGCTCTTCCCCTCTGCTGCTTACTATTT
AGGAGCCTACGTTTTTATTATCTTCACCGGCTTCCTCATTACCTTCTTGGCCTTTACCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGAC
TTTTGAGGATATCACACGGGCCTTTGAAGGGCAGGCACACGGTGCAGATAGATCTGGGAAGGACGGCGTCATGGGGATGAACAGCATCGA
GCCTGCTAAGGAGACCACCACCAATGTCTAAGTCATGCCTCCTTCCACCTCCCTCCCGGCATGGGAAAGCCACCTCTCCCTCAACAAGGG
AGAGACTTTATCAGGATGAACCCAGGACTGCTTCTGAATGCTGCTACTTGATTTCTTTCTCATCCCACGCACTCCATGAGCACCCCAAGG
CTGCAGTTTGTTGGATCTTCAATGGCTTTTTAAATTTTATTTCCTGGACATCCTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCA
TTTCAGGAGGGATTGGCCGCTTGGCACATGACAACTTTGCCAGCTTTTCCTCCCTTGGGTTCTGATATTGCCGCACTAGAGGATATAGGA
GAGGAAAAGTAAGGTGCAGTTGCCCCAACCTCAGACTTACCAGGAAGCAGATACATATGAGTGTGGAAGCCGGAGGGTGTTTATGTAAGA
GCACCTTCCTCACTTCCATACAGCTCTACGCGGCAAATTAACTTGAGTTTTATTTATCTTATCCTCTGGTTTAATTACATAAATATTTAT
TTTTTAAGTGTAATTTTGCCAAATAATAAAAACAGAAGGAAATTGAGATTAGAGGGAGGTGTTTAAAGAGAGGTTATAGAGTAAAAGATT
TGATGCTGGAGAGGTTAAGGTGCAATAAGAATTCAGGGAGAAATGTTGTTCATTATTGGAGGGTAAATGATGTGGTGCCTGAGGTCTGTA
CATTACCTCTTAACAATTTCTGTCCTTCAGATGGAAACTCTTTGATTTCTCAGAAAAGTTGTATGCCTATTTAATAAAGCTACTCATTTC
CTTTGGAACTTTATCTTTAAGATAATAGTTTACATGTAGTAGTACTTGAAATCTAGGATTATTAACTAATATGGGCATTGTAGTTAATGG
CGGTTGATGGGTTCTAATTTTGGATGGAGTCCAGGGAAGAGAAAGTGATTTCTAGAAAGCCTGTTCCCCTCACTGGACGAAATAACTCCT
TGTAGTAGTCTCATTACTTTTGAAGTAATCCCGCCACCTATCTAGTGGGAGAGCCATCCAAATGAGAAACCTAAAATAATTGGTTCTTGG
TAGAGATTCATTATTTCTCCACTTTGTTCTTTAGGAGATTTTAGGTGTTGATTTTCTGTTTTATTTTAACTCATACCTTTAAAGGAATTC
CCCAAAGAATGTTTACAGCAAACTTGGAATTTGTAACCTCAGCTCTGGGAGAGGATTTTTTTCTGAGCGATTATTATCTAAAGTGTGTTG
TTGCTTTAGGCTCACGGCACGCTTGCGTATGTCTGTTACCATGTCACTGTGGTCCTATGCCGAATGCCCTCAGGGGACTTGAATCTTTCC
AATAAACCAGGTTTAGACAGTATGAGTCAATGTGCAGTGCAGCCCACACTTGAGAGGATGAATGTATGTGCACTGTCACTTTGCTCTGGG
TGGAAGTATGTTATTGTTGACTTATTTTCTCTGTGTTTGTTCCTACAGCCCCTTTTTCATATGTTGCTCAGTCTCCCTTTCCCTTCTTGG
TGCTTACACATCTCAGACCCTTTAGCCAAACCCTTGCCAGTGACAGTATTTTGGTTCTCAGTTCTCACTGTTCCCTCTGCTCCTGGAGCC
TTTGAATAAAAATGCACGTAGCTATGGAGTGGGGTTTAGCTGGAAAGGTGGCCTTCCAACTTCACGTCAACTTCTGGCTCCTCAGTTTGG
CAGTAAGGCAGGGAAGTTGTTTTCCTATTTCTCACTGAGAAGATTGTGAATATTTCCATATGGATTTTCCATTATTGTTTGTTTGATTCT

>43436_43436_2_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000256078_SLC2A14_chr12_7985410_ENST00000431042_length(amino acids)=531AA_BP=40
MLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPS
EVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI
SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV
SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL
VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL

--------------------------------------------------------------
>43436_43436_3_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000256078_SLC2A14_chr12_7985410_ENST00000543909_length(transcript)=3453nt_BP=175nt
CTGAAGGCGGCGGCGGGGCCAGAGGCTCAGCGGCTCCCAGGTGCGGGAGAGAGGCCTGCTGAAAATGACTGAATATAAACTTGTGGTAGT
TGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTCAGAATCATTTTGTGGACGAATATGATCCAACAATAGAGGTCAC
CCCAGCTCTGATCTTTGCCATCACAGTTGCTACAATCGGCTCTTTCCAGTTTGGCTACAACACTGGGGTCATCAATGCTCCTGAGACGAT
CATAAAGGAATTTATCAATAAAACTTTGACGGACAAGGCAAATGCCCCTCCCTCTGAGGTGCTGCTCACGAATCTCTGGTCCTTGTCTGT
GGCCATATTTTCCGTCGGGGGTATGATCGGCTCCTTTTCCGTCGGACTCTTTGTTAACCGCTTTGGCAGGCGCAATTCAATGCTGATTGT
CAACCTGTTGGCTGCCACTGGTGGCTGCCTTATGGGACTGTGTAAAATAGCTGAGTCAGTTGAAATGCTGATCCTGGGCCGCTTGGTTAT
TGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCCCATGTACATTGGAGAGATCTCGCCTACTGCCCTGAGGGGTGCCTTTGGCACTCT
CAACCAGCTGGGCATAGTTATTGGAATTCTGGTGGCCCAGATCTTTGGTCTGGAACTCATCCTTGGGTCTGAAGAGCTATGGCCGGTGCT
ATTAGGCTTTACCATCCTTCCAGCTATCCTGCAAAGTGCAGCCCTTCCATGTTGCCCTGAAAGTCCCAGATTTTTGCTCATTAACAGAAA
AAAAGAGGAGAATGCTACGCGGATCCTCCAGCGGTTGTGGGGCACCCAGGATGTATCCCAAGACATCCAGGAGATGAAAGATGAGAGTGC
AAGGATGTCACAAGAAAAGCAAGTCACCGTGCTGGAGCTCTTTAGAGTGTCCAGCTACCGACAGCCCATCATCATTTCCATTGTGCTCCA
GCTCTCTCAGCAGCTCTCTGGGATCAATGCTGTGTTCTATTACTCAACAGGAATCTTCAAGGATGCAGGTGTTCAACAGCCCATCTATGC
CACCATCAGCGCGGGTGTGGTTAATACTATCTTCACTTTACTTTCTCTATTTCTGGTGGAAAGGGCAGGAAGAAGGACTCTGCATATGAT
AGGCCTTGGAGGGATGGCTTTTTGTTCCACGCTCATGACTGTTTCTTTGTTATTAAAGAATCACTATAATGGGATGAGCTTTGTCTGTAT
TGGGGCTATCTTGGTCTTTGTGGCCTGTTTTGAAATTGGACCAGGCCCCATTCCCTGGTTTATTGTGGCCGAACTCTTCAGCCAGGGCCC
CCGCCCAGCTGCGATGGCAGTGGCCGGCTGCTCCAACTGGACCTCCAACTTCCTAGTCGGATTGCTCTTCCCCTCTGCTGCTTACTATTT
AGGAGCCTACGTTTTTATTATCTTCACCGGCTTCCTCATTACCTTCTTGGCCTTTACCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGAC
TTTTGAGGATATCACACGGGCCTTTGAAGGGCAGGCACACGGTGCAGATAGATCTGGGAAGGACGGCGTCATGGGGATGAACAGCATCGA
GCCTGCTAAGGAGACCACCACCAATGTCTAAGTCATGCCTCCTTCCACCTCCCTCCCGGCATGGGAAAGCCACCTCTCCCTCAACAAGGG
AGAGACTTTATCAGGATGAACCCAGGACTGCTTCTGAATGCTGCTACTTGATTTCTTTCTCATCCCACGCACTCCATGAGCACCCCAAGG
CTGCAGTTTGTTGGATCTTCAATGGCTTTTTAAATTTTATTTCCTGGACATCCTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCA
TTTCAGGAGGGATTGGCCGCTTGGCACATGACAACTTTGCCAGCTTTTCCTCCCTTGGGTTCTGATATTGCCGCACTAGAGGATATAGGA
GAGGAAAAGTAAGGTGCAGTTGCCCCAACCTCAGACTTACCAGGAAGCAGATACATATGAGTGTGGAAGCCGGAGGGTGTTTATGTAAGA
GCACCTTCCTCACTTCCATACAGCTCTACGCGGCAAATTAACTTGAGTTTTATTTATCTTATCCTCTGGTTTAATTACATAAATATTTAT
TTTTTAAGTGTAATTTTGCCAAATAATAAAAACAGAAGGAAATTGAGATTAGAGGGAGGTGTTTAAAGAGAGGTTATAGAGTAAAAGATT
TGATGCTGGAGAGGTTAAGGTGCAATAAGAATTCAGGGAGAAATGTTGTTCATTATTGGAGGGTAAATGATGTGGTGCCTGAGGTCTGTA
CATTACCTCTTAACAATTTCTGTCCTTCAGATGGAAACTCTTTGATTTCTCAGAAAAGTTGTATGCCTATTTAATAAAGCTACTCATTTC
CTTTGGAACTTTATCTTTAAGATAATAGTTTACATGTAGTAGTACTTGAAATCTAGGATTATTAACTAATATGGGCATTGTAGTTAATGG
CGGTTGATGGGTTCTAATTTTGGATGGAGTCCAGGGAAGAGAAAGTGATTTCTAGAAAGCCTGTTCCCCTCACTGGACGAAATAACTCCT
TGTAGTAGTCTCATTACTTTTGAAGTAATCCCGCCACCTATCTAGTGGGAGAGCCATCCAAATGAGAAACCTAAAATAATTGGTTCTTGG
TAGAGATTCATTATTTCTCCACTTTGTTCTTTAGGAGATTTTAGGTGTTGATTTTCTGTTTTATTTTAACTCATACCTTTAAAGGAATTC
CCCAAAGAATGTTTACAGCAAACTTGGAATTTGTAACCTCAGCTCTGGGAGAGGATTTTTTTCTGAGCGATTATTATCTAAAGTGTGTTG
TTGCTTTAGGCTCACGGCACGCTTGCGTATGTCTGTTACCATGTCACTGTGGTCCTATGCCGAATGCCCTCAGGGGACTTGAATCTTTCC
AATAAACCAGGTTTAGACAGTATGAGTCAATGTGCAGTGCAGCCCACACTTGAGAGGATGAATGTATGTGCACTGTCACTTTGCTCTGGG
TGGAAGTATGTTATTGTTGACTTATTTTCTCTGTGTTTGTTCCTACAGCCCCTTTTTCATATGTTGCTCAGTCTCCCTTTCCCTTCTTGG
TGCTTACACATCTCAGACCCTTTAGCCAAACCCTTGCCAGTGACAGTATTTTGGTTCTCAGTTCTCACTGTTCCCTCTGCTCCTGGAGCC
TTTGAATAAAAATGCACGTAGCTATGGAGTGGGGTTTAGCTGGAAAGGTGGCCTTCCAACTTCACGTCAACTTCTGGCTCCTCAGTTTGG
CAGTAAGGCAGGGAAGTTGTTTTCCTATTTCTCACTGAGAAGATTGTGAATATTTCCATATGGATTTTCCATTATTGTTTGTTTGATTCT

>43436_43436_3_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000256078_SLC2A14_chr12_7985410_ENST00000543909_length(amino acids)=531AA_BP=40
MLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPS
EVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI
SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV
SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL
VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL

--------------------------------------------------------------
>43436_43436_4_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000311936_SLC2A14_chr12_7985410_ENST00000340749_length(transcript)=3583nt_BP=303nt
TCCTAGGCGGCGGCCGCGGCGGCGGAGGCAGCAGCGGCGGCGGCAGTGGCGGCGGCGAAGGTGGCGGCGGCTCGGCCAGTACTCCCGGCC
CCCGCCATTTCGGACTGGGAGCGAGCGCGGCGCAGGCACTGAAGGCGGCGGCGGGGCCAGAGGCTCAGCGGCTCCCAGGTGCGGGAGAGA
GGCCTGCTGAAAATGACTGAATATAAACTTGTGGTAGTTGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTCAGAAT
CATTTTGTGGACGAATATGATCCAACAATAGAGGTCACCCCAGCTCTGATCTTTGCCATCACAGTTGCTACAATCGGCTCTTTCCAGTTT
GGCTACAACACTGGGGTCATCAATGCTCCTGAGACGATCATAAAGGAATTTATCAATAAAACTTTGACGGACAAGGCAAATGCCCCTCCC
TCTGAGGTGCTGCTCACGAATCTCTGGTCCTTGTCTGTGGCCATATTTTCCGTCGGGGGTATGATCGGCTCCTTTTCCGTCGGACTCTTT
GTTAACCGCTTTGGCAGGCGCAATTCAATGCTGATTGTCAACCTGTTGGCTGCCACTGGTGGCTGCCTTATGGGACTGTGTAAAATAGCT
GAGTCAGTTGAAATGCTGATCCTGGGCCGCTTGGTTATTGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCCCATGTACATTGGAGAG
ATCTCGCCTACTGCCCTGAGGGGTGCCTTTGGCACTCTCAACCAGCTGGGCATAGTTATTGGAATTCTGGTGGCCCAGATCTTTGGTCTG
GAACTCATCCTTGGGTCTGAAGAGCTATGGCCGGTGCTATTAGGCTTTACCATCCTTCCAGCTATCCTGCAAAGTGCAGCCCTTCCATGT
TGCCCTGAAAGTCCCAGATTTTTGCTCATTAACAGAAAAAAAGAGGAGAATGCTACGCGGATCCTCCAGCGGTTGTGGGGCACCCAGGAT
GTATCCCAAGACATCCAGGAGATGAAAGATGAGAGTGCAAGGATGTCACAAGAAAAGCAAGTCACCGTGCTGGAGCTCTTTAGAGTGTCC
AGCTACCGACAGCCCATCATCATTTCCATTGTGCTCCAGCTCTCTCAGCAGCTCTCTGGGATCAATGCTGTGTTCTATTACTCAACAGGA
ATCTTCAAGGATGCAGGTGTTCAACAGCCCATCTATGCCACCATCAGCGCGGGTGTGGTTAATACTATCTTCACTTTACTTTCTCTATTT
CTGGTGGAAAGGGCAGGAAGAAGGACTCTGCATATGATAGGCCTTGGAGGGATGGCTTTTTGTTCCACGCTCATGACTGTTTCTTTGTTA
TTAAAGAATCACTATAATGGGATGAGCTTTGTCTGTATTGGGGCTATCTTGGTCTTTGTGGCCTGTTTTGAAATTGGACCAGGCCCCATT
CCCTGGTTTATTGTGGCCGAACTCTTCAGCCAGGGCCCCCGCCCAGCTGCGATGGCAGTGGCCGGCTGCTCCAACTGGACCTCCAACTTC
CTAGTCGGATTGCTCTTCCCCTCTGCTGCTTACTATTTAGGAGCCTACGTTTTTATTATCTTCACCGGCTTCCTCATTACCTTCTTGGCC
TTTACCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGACTTTTGAGGATATCACACGGGCCTTTGAAGGGCAGGCACACGGTGCAGATAGA
TCTGGGAAGGACGGCGTCATGGGGATGAACAGCATCGAGCCTGCTAAGGAGACCACCACCAATGTCTAAGTCATGCCTCCTTCCACCTCC
CTCCCGGCATGGGAAAGCCACCTCTCCCTCAACAAGGGAGAGACTTTATCAGGATGAACCCAGGACTGCTTCTGAATGCTGCTACTTGAT
TTCTTTCTCATCCCACGCACTCCATGAGCACCCCAAGGCTGCAGTTTGTTGGATCTTCAATGGCTTTTTAAATTTTATTTCCTGGACATC
CTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCATTTCAGGAGGGATTGGCCGCTTGGCACATGACAACTTTGCCAGCTTTTCCTC
CCTTGGGTTCTGATATTGCCGCACTAGAGGATATAGGAGAGGAAAAGTAAGGTGCAGTTGCCCCAACCTCAGACTTACCAGGAAGCAGAT
ACATATGAGTGTGGAAGCCGGAGGGTGTTTATGTAAGAGCACCTTCCTCACTTCCATACAGCTCTACGCGGCAAATTAACTTGAGTTTTA
TTTATCTTATCCTCTGGTTTAATTACATAAATATTTATTTTTTAAGTGTAATTTTGCCAAATAATAAAAACAGAAGGAAATTGAGATTAG
AGGGAGGTGTTTAAAGAGAGGTTATAGAGTAAAAGATTTGATGCTGGAGAGGTTAAGGTGCAATAAGAATTCAGGGAGAAATGTTGTTCA
TTATTGGAGGGTAAATGATGTGGTGCCTGAGGTCTGTACATTACCTCTTAACAATTTCTGTCCTTCAGATGGAAACTCTTTGATTTCTCA
GAAAAGTTGTATGCCTATTTAATAAAGCTACTCATTTCCTTTGGAACTTTATCTTTAAGATAATAGTTTACATGTAGTAGTACTTGAAAT
CTAGGATTATTAACTAATATGGGCATTGTAGTTAATGGCGGTTGATGGGTTCTAATTTTGGATGGAGTCCAGGGAAGAGAAAGTGATTTC
TAGAAAGCCTGTTCCCCTCACTGGACGAAATAACTCCTTGTAGTAGTCTCATTACTTTTGAAGTAATCCCGCCACCTATCTAGTGGGAGA
GCCATCCAAATGAGAAACCTAAAATAATTGGTTCTTGGTAGAGATTCATTATTTCTCCACTTTGTTCTTTAGGAGATTTTAGGTGTTGAT
TTTCTGTTTTATTTTAACTCATACCTTTAAAGGAATTCCCCAAAGAATGTTTACAGCAAACTTGGAATTTGTAACCTCAGCTCTGGGAGA
GGATTTTTTTCTGAGCGATTATTATCTAAAGTGTGTTGTTGCTTTAGGCTCACGGCACGCTTGCGTATGTCTGTTACCATGTCACTGTGG
TCCTATGCCGAATGCCCTCAGGGGACTTGAATCTTTCCAATAAACCAGGTTTAGACAGTATGAGTCAATGTGCAGTGCAGCCCACACTTG
AGAGGATGAATGTATGTGCACTGTCACTTTGCTCTGGGTGGAAGTATGTTATTGTTGACTTATTTTCTCTGTGTTTGTTCCTACAGCCCC
TTTTTCATATGTTGCTCAGTCTCCCTTTCCCTTCTTGGTGCTTACACATCTCAGACCCTTTAGCCAAACCCTTGCCAGTGACAGTATTTT
GGTTCTCAGTTCTCACTGTTCCCTCTGCTCCTGGAGCCTTTGAATAAAAATGCACGTAGCTATGGAGTGGGGTTTAGCTGGAAAGGTGGC
CTTCCAACTTCACGTCAACTTCTGGCTCCTCAGTTTGGCAGTAAGGCAGGGAAGTTGTTTTCCTATTTCTCACTGAGAAGATTGTGAATA

>43436_43436_4_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000311936_SLC2A14_chr12_7985410_ENST00000340749_length(amino acids)=531AA_BP=40
MLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPS
EVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI
SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV
SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL
VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL

--------------------------------------------------------------
>43436_43436_5_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000311936_SLC2A14_chr12_7985410_ENST00000431042_length(transcript)=3576nt_BP=303nt
TCCTAGGCGGCGGCCGCGGCGGCGGAGGCAGCAGCGGCGGCGGCAGTGGCGGCGGCGAAGGTGGCGGCGGCTCGGCCAGTACTCCCGGCC
CCCGCCATTTCGGACTGGGAGCGAGCGCGGCGCAGGCACTGAAGGCGGCGGCGGGGCCAGAGGCTCAGCGGCTCCCAGGTGCGGGAGAGA
GGCCTGCTGAAAATGACTGAATATAAACTTGTGGTAGTTGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTCAGAAT
CATTTTGTGGACGAATATGATCCAACAATAGAGGTCACCCCAGCTCTGATCTTTGCCATCACAGTTGCTACAATCGGCTCTTTCCAGTTT
GGCTACAACACTGGGGTCATCAATGCTCCTGAGACGATCATAAAGGAATTTATCAATAAAACTTTGACGGACAAGGCAAATGCCCCTCCC
TCTGAGGTGCTGCTCACGAATCTCTGGTCCTTGTCTGTGGCCATATTTTCCGTCGGGGGTATGATCGGCTCCTTTTCCGTCGGACTCTTT
GTTAACCGCTTTGGCAGGCGCAATTCAATGCTGATTGTCAACCTGTTGGCTGCCACTGGTGGCTGCCTTATGGGACTGTGTAAAATAGCT
GAGTCAGTTGAAATGCTGATCCTGGGCCGCTTGGTTATTGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCCCATGTACATTGGAGAG
ATCTCGCCTACTGCCCTGAGGGGTGCCTTTGGCACTCTCAACCAGCTGGGCATAGTTATTGGAATTCTGGTGGCCCAGATCTTTGGTCTG
GAACTCATCCTTGGGTCTGAAGAGCTATGGCCGGTGCTATTAGGCTTTACCATCCTTCCAGCTATCCTGCAAAGTGCAGCCCTTCCATGT
TGCCCTGAAAGTCCCAGATTTTTGCTCATTAACAGAAAAAAAGAGGAGAATGCTACGCGGATCCTCCAGCGGTTGTGGGGCACCCAGGAT
GTATCCCAAGACATCCAGGAGATGAAAGATGAGAGTGCAAGGATGTCACAAGAAAAGCAAGTCACCGTGCTGGAGCTCTTTAGAGTGTCC
AGCTACCGACAGCCCATCATCATTTCCATTGTGCTCCAGCTCTCTCAGCAGCTCTCTGGGATCAATGCTGTGTTCTATTACTCAACAGGA
ATCTTCAAGGATGCAGGTGTTCAACAGCCCATCTATGCCACCATCAGCGCGGGTGTGGTTAATACTATCTTCACTTTACTTTCTCTATTT
CTGGTGGAAAGGGCAGGAAGAAGGACTCTGCATATGATAGGCCTTGGAGGGATGGCTTTTTGTTCCACGCTCATGACTGTTTCTTTGTTA
TTAAAGAATCACTATAATGGGATGAGCTTTGTCTGTATTGGGGCTATCTTGGTCTTTGTGGCCTGTTTTGAAATTGGACCAGGCCCCATT
CCCTGGTTTATTGTGGCCGAACTCTTCAGCCAGGGCCCCCGCCCAGCTGCGATGGCAGTGGCCGGCTGCTCCAACTGGACCTCCAACTTC
CTAGTCGGATTGCTCTTCCCCTCTGCTGCTTACTATTTAGGAGCCTACGTTTTTATTATCTTCACCGGCTTCCTCATTACCTTCTTGGCC
TTTACCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGACTTTTGAGGATATCACACGGGCCTTTGAAGGGCAGGCACACGGTGCAGATAGA
TCTGGGAAGGACGGCGTCATGGGGATGAACAGCATCGAGCCTGCTAAGGAGACCACCACCAATGTCTAAGTCATGCCTCCTTCCACCTCC
CTCCCGGCATGGGAAAGCCACCTCTCCCTCAACAAGGGAGAGACTTTATCAGGATGAACCCAGGACTGCTTCTGAATGCTGCTACTTGAT
TTCTTTCTCATCCCACGCACTCCATGAGCACCCCAAGGCTGCAGTTTGTTGGATCTTCAATGGCTTTTTAAATTTTATTTCCTGGACATC
CTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCATTTCAGGAGGGATTGGCCGCTTGGCACATGACAACTTTGCCAGCTTTTCCTC
CCTTGGGTTCTGATATTGCCGCACTAGAGGATATAGGAGAGGAAAAGTAAGGTGCAGTTGCCCCAACCTCAGACTTACCAGGAAGCAGAT
ACATATGAGTGTGGAAGCCGGAGGGTGTTTATGTAAGAGCACCTTCCTCACTTCCATACAGCTCTACGCGGCAAATTAACTTGAGTTTTA
TTTATCTTATCCTCTGGTTTAATTACATAAATATTTATTTTTTAAGTGTAATTTTGCCAAATAATAAAAACAGAAGGAAATTGAGATTAG
AGGGAGGTGTTTAAAGAGAGGTTATAGAGTAAAAGATTTGATGCTGGAGAGGTTAAGGTGCAATAAGAATTCAGGGAGAAATGTTGTTCA
TTATTGGAGGGTAAATGATGTGGTGCCTGAGGTCTGTACATTACCTCTTAACAATTTCTGTCCTTCAGATGGAAACTCTTTGATTTCTCA
GAAAAGTTGTATGCCTATTTAATAAAGCTACTCATTTCCTTTGGAACTTTATCTTTAAGATAATAGTTTACATGTAGTAGTACTTGAAAT
CTAGGATTATTAACTAATATGGGCATTGTAGTTAATGGCGGTTGATGGGTTCTAATTTTGGATGGAGTCCAGGGAAGAGAAAGTGATTTC
TAGAAAGCCTGTTCCCCTCACTGGACGAAATAACTCCTTGTAGTAGTCTCATTACTTTTGAAGTAATCCCGCCACCTATCTAGTGGGAGA
GCCATCCAAATGAGAAACCTAAAATAATTGGTTCTTGGTAGAGATTCATTATTTCTCCACTTTGTTCTTTAGGAGATTTTAGGTGTTGAT
TTTCTGTTTTATTTTAACTCATACCTTTAAAGGAATTCCCCAAAGAATGTTTACAGCAAACTTGGAATTTGTAACCTCAGCTCTGGGAGA
GGATTTTTTTCTGAGCGATTATTATCTAAAGTGTGTTGTTGCTTTAGGCTCACGGCACGCTTGCGTATGTCTGTTACCATGTCACTGTGG
TCCTATGCCGAATGCCCTCAGGGGACTTGAATCTTTCCAATAAACCAGGTTTAGACAGTATGAGTCAATGTGCAGTGCAGCCCACACTTG
AGAGGATGAATGTATGTGCACTGTCACTTTGCTCTGGGTGGAAGTATGTTATTGTTGACTTATTTTCTCTGTGTTTGTTCCTACAGCCCC
TTTTTCATATGTTGCTCAGTCTCCCTTTCCCTTCTTGGTGCTTACACATCTCAGACCCTTTAGCCAAACCCTTGCCAGTGACAGTATTTT
GGTTCTCAGTTCTCACTGTTCCCTCTGCTCCTGGAGCCTTTGAATAAAAATGCACGTAGCTATGGAGTGGGGTTTAGCTGGAAAGGTGGC
CTTCCAACTTCACGTCAACTTCTGGCTCCTCAGTTTGGCAGTAAGGCAGGGAAGTTGTTTTCCTATTTCTCACTGAGAAGATTGTGAATA

>43436_43436_5_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000311936_SLC2A14_chr12_7985410_ENST00000431042_length(amino acids)=531AA_BP=40
MLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPS
EVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI
SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV
SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL
VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL

--------------------------------------------------------------
>43436_43436_6_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000311936_SLC2A14_chr12_7985410_ENST00000543909_length(transcript)=3581nt_BP=303nt
TCCTAGGCGGCGGCCGCGGCGGCGGAGGCAGCAGCGGCGGCGGCAGTGGCGGCGGCGAAGGTGGCGGCGGCTCGGCCAGTACTCCCGGCC
CCCGCCATTTCGGACTGGGAGCGAGCGCGGCGCAGGCACTGAAGGCGGCGGCGGGGCCAGAGGCTCAGCGGCTCCCAGGTGCGGGAGAGA
GGCCTGCTGAAAATGACTGAATATAAACTTGTGGTAGTTGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTCAGAAT
CATTTTGTGGACGAATATGATCCAACAATAGAGGTCACCCCAGCTCTGATCTTTGCCATCACAGTTGCTACAATCGGCTCTTTCCAGTTT
GGCTACAACACTGGGGTCATCAATGCTCCTGAGACGATCATAAAGGAATTTATCAATAAAACTTTGACGGACAAGGCAAATGCCCCTCCC
TCTGAGGTGCTGCTCACGAATCTCTGGTCCTTGTCTGTGGCCATATTTTCCGTCGGGGGTATGATCGGCTCCTTTTCCGTCGGACTCTTT
GTTAACCGCTTTGGCAGGCGCAATTCAATGCTGATTGTCAACCTGTTGGCTGCCACTGGTGGCTGCCTTATGGGACTGTGTAAAATAGCT
GAGTCAGTTGAAATGCTGATCCTGGGCCGCTTGGTTATTGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCCCATGTACATTGGAGAG
ATCTCGCCTACTGCCCTGAGGGGTGCCTTTGGCACTCTCAACCAGCTGGGCATAGTTATTGGAATTCTGGTGGCCCAGATCTTTGGTCTG
GAACTCATCCTTGGGTCTGAAGAGCTATGGCCGGTGCTATTAGGCTTTACCATCCTTCCAGCTATCCTGCAAAGTGCAGCCCTTCCATGT
TGCCCTGAAAGTCCCAGATTTTTGCTCATTAACAGAAAAAAAGAGGAGAATGCTACGCGGATCCTCCAGCGGTTGTGGGGCACCCAGGAT
GTATCCCAAGACATCCAGGAGATGAAAGATGAGAGTGCAAGGATGTCACAAGAAAAGCAAGTCACCGTGCTGGAGCTCTTTAGAGTGTCC
AGCTACCGACAGCCCATCATCATTTCCATTGTGCTCCAGCTCTCTCAGCAGCTCTCTGGGATCAATGCTGTGTTCTATTACTCAACAGGA
ATCTTCAAGGATGCAGGTGTTCAACAGCCCATCTATGCCACCATCAGCGCGGGTGTGGTTAATACTATCTTCACTTTACTTTCTCTATTT
CTGGTGGAAAGGGCAGGAAGAAGGACTCTGCATATGATAGGCCTTGGAGGGATGGCTTTTTGTTCCACGCTCATGACTGTTTCTTTGTTA
TTAAAGAATCACTATAATGGGATGAGCTTTGTCTGTATTGGGGCTATCTTGGTCTTTGTGGCCTGTTTTGAAATTGGACCAGGCCCCATT
CCCTGGTTTATTGTGGCCGAACTCTTCAGCCAGGGCCCCCGCCCAGCTGCGATGGCAGTGGCCGGCTGCTCCAACTGGACCTCCAACTTC
CTAGTCGGATTGCTCTTCCCCTCTGCTGCTTACTATTTAGGAGCCTACGTTTTTATTATCTTCACCGGCTTCCTCATTACCTTCTTGGCC
TTTACCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGACTTTTGAGGATATCACACGGGCCTTTGAAGGGCAGGCACACGGTGCAGATAGA
TCTGGGAAGGACGGCGTCATGGGGATGAACAGCATCGAGCCTGCTAAGGAGACCACCACCAATGTCTAAGTCATGCCTCCTTCCACCTCC
CTCCCGGCATGGGAAAGCCACCTCTCCCTCAACAAGGGAGAGACTTTATCAGGATGAACCCAGGACTGCTTCTGAATGCTGCTACTTGAT
TTCTTTCTCATCCCACGCACTCCATGAGCACCCCAAGGCTGCAGTTTGTTGGATCTTCAATGGCTTTTTAAATTTTATTTCCTGGACATC
CTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCATTTCAGGAGGGATTGGCCGCTTGGCACATGACAACTTTGCCAGCTTTTCCTC
CCTTGGGTTCTGATATTGCCGCACTAGAGGATATAGGAGAGGAAAAGTAAGGTGCAGTTGCCCCAACCTCAGACTTACCAGGAAGCAGAT
ACATATGAGTGTGGAAGCCGGAGGGTGTTTATGTAAGAGCACCTTCCTCACTTCCATACAGCTCTACGCGGCAAATTAACTTGAGTTTTA
TTTATCTTATCCTCTGGTTTAATTACATAAATATTTATTTTTTAAGTGTAATTTTGCCAAATAATAAAAACAGAAGGAAATTGAGATTAG
AGGGAGGTGTTTAAAGAGAGGTTATAGAGTAAAAGATTTGATGCTGGAGAGGTTAAGGTGCAATAAGAATTCAGGGAGAAATGTTGTTCA
TTATTGGAGGGTAAATGATGTGGTGCCTGAGGTCTGTACATTACCTCTTAACAATTTCTGTCCTTCAGATGGAAACTCTTTGATTTCTCA
GAAAAGTTGTATGCCTATTTAATAAAGCTACTCATTTCCTTTGGAACTTTATCTTTAAGATAATAGTTTACATGTAGTAGTACTTGAAAT
CTAGGATTATTAACTAATATGGGCATTGTAGTTAATGGCGGTTGATGGGTTCTAATTTTGGATGGAGTCCAGGGAAGAGAAAGTGATTTC
TAGAAAGCCTGTTCCCCTCACTGGACGAAATAACTCCTTGTAGTAGTCTCATTACTTTTGAAGTAATCCCGCCACCTATCTAGTGGGAGA
GCCATCCAAATGAGAAACCTAAAATAATTGGTTCTTGGTAGAGATTCATTATTTCTCCACTTTGTTCTTTAGGAGATTTTAGGTGTTGAT
TTTCTGTTTTATTTTAACTCATACCTTTAAAGGAATTCCCCAAAGAATGTTTACAGCAAACTTGGAATTTGTAACCTCAGCTCTGGGAGA
GGATTTTTTTCTGAGCGATTATTATCTAAAGTGTGTTGTTGCTTTAGGCTCACGGCACGCTTGCGTATGTCTGTTACCATGTCACTGTGG
TCCTATGCCGAATGCCCTCAGGGGACTTGAATCTTTCCAATAAACCAGGTTTAGACAGTATGAGTCAATGTGCAGTGCAGCCCACACTTG
AGAGGATGAATGTATGTGCACTGTCACTTTGCTCTGGGTGGAAGTATGTTATTGTTGACTTATTTTCTCTGTGTTTGTTCCTACAGCCCC
TTTTTCATATGTTGCTCAGTCTCCCTTTCCCTTCTTGGTGCTTACACATCTCAGACCCTTTAGCCAAACCCTTGCCAGTGACAGTATTTT
GGTTCTCAGTTCTCACTGTTCCCTCTGCTCCTGGAGCCTTTGAATAAAAATGCACGTAGCTATGGAGTGGGGTTTAGCTGGAAAGGTGGC
CTTCCAACTTCACGTCAACTTCTGGCTCCTCAGTTTGGCAGTAAGGCAGGGAAGTTGTTTTCCTATTTCTCACTGAGAAGATTGTGAATA

>43436_43436_6_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000311936_SLC2A14_chr12_7985410_ENST00000543909_length(amino acids)=531AA_BP=40
MLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPS
EVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI
SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV
SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL
VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL

--------------------------------------------------------------
>43436_43436_7_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000557334_SLC2A14_chr12_7985410_ENST00000340749_length(transcript)=3588nt_BP=308nt
GATTTTCCTAGGCGGCGGCCGCGGCGGCGGAGGCAGCAGCGGCGGCGGCAGTGGCGGCGGCGAAGGTGGCGGCGGCTCGGCCAGTACTCC
CGGCCCCCGCCATTTCGGACTGGGAGCGAGCGCGGCGCAGGCACTGAAGGCGGCGGCGGGGCCAGAGGCTCAGCGGCTCCCAGGTGCGGG
AGAGAGGCCTGCTGAAAATGACTGAATATAAACTTGTGGTAGTTGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTC
AGAATCATTTTGTGGACGAATATGATCCAACAATAGAGGTCACCCCAGCTCTGATCTTTGCCATCACAGTTGCTACAATCGGCTCTTTCC
AGTTTGGCTACAACACTGGGGTCATCAATGCTCCTGAGACGATCATAAAGGAATTTATCAATAAAACTTTGACGGACAAGGCAAATGCCC
CTCCCTCTGAGGTGCTGCTCACGAATCTCTGGTCCTTGTCTGTGGCCATATTTTCCGTCGGGGGTATGATCGGCTCCTTTTCCGTCGGAC
TCTTTGTTAACCGCTTTGGCAGGCGCAATTCAATGCTGATTGTCAACCTGTTGGCTGCCACTGGTGGCTGCCTTATGGGACTGTGTAAAA
TAGCTGAGTCAGTTGAAATGCTGATCCTGGGCCGCTTGGTTATTGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCCCATGTACATTG
GAGAGATCTCGCCTACTGCCCTGAGGGGTGCCTTTGGCACTCTCAACCAGCTGGGCATAGTTATTGGAATTCTGGTGGCCCAGATCTTTG
GTCTGGAACTCATCCTTGGGTCTGAAGAGCTATGGCCGGTGCTATTAGGCTTTACCATCCTTCCAGCTATCCTGCAAAGTGCAGCCCTTC
CATGTTGCCCTGAAAGTCCCAGATTTTTGCTCATTAACAGAAAAAAAGAGGAGAATGCTACGCGGATCCTCCAGCGGTTGTGGGGCACCC
AGGATGTATCCCAAGACATCCAGGAGATGAAAGATGAGAGTGCAAGGATGTCACAAGAAAAGCAAGTCACCGTGCTGGAGCTCTTTAGAG
TGTCCAGCTACCGACAGCCCATCATCATTTCCATTGTGCTCCAGCTCTCTCAGCAGCTCTCTGGGATCAATGCTGTGTTCTATTACTCAA
CAGGAATCTTCAAGGATGCAGGTGTTCAACAGCCCATCTATGCCACCATCAGCGCGGGTGTGGTTAATACTATCTTCACTTTACTTTCTC
TATTTCTGGTGGAAAGGGCAGGAAGAAGGACTCTGCATATGATAGGCCTTGGAGGGATGGCTTTTTGTTCCACGCTCATGACTGTTTCTT
TGTTATTAAAGAATCACTATAATGGGATGAGCTTTGTCTGTATTGGGGCTATCTTGGTCTTTGTGGCCTGTTTTGAAATTGGACCAGGCC
CCATTCCCTGGTTTATTGTGGCCGAACTCTTCAGCCAGGGCCCCCGCCCAGCTGCGATGGCAGTGGCCGGCTGCTCCAACTGGACCTCCA
ACTTCCTAGTCGGATTGCTCTTCCCCTCTGCTGCTTACTATTTAGGAGCCTACGTTTTTATTATCTTCACCGGCTTCCTCATTACCTTCT
TGGCCTTTACCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGACTTTTGAGGATATCACACGGGCCTTTGAAGGGCAGGCACACGGTGCAG
ATAGATCTGGGAAGGACGGCGTCATGGGGATGAACAGCATCGAGCCTGCTAAGGAGACCACCACCAATGTCTAAGTCATGCCTCCTTCCA
CCTCCCTCCCGGCATGGGAAAGCCACCTCTCCCTCAACAAGGGAGAGACTTTATCAGGATGAACCCAGGACTGCTTCTGAATGCTGCTAC
TTGATTTCTTTCTCATCCCACGCACTCCATGAGCACCCCAAGGCTGCAGTTTGTTGGATCTTCAATGGCTTTTTAAATTTTATTTCCTGG
ACATCCTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCATTTCAGGAGGGATTGGCCGCTTGGCACATGACAACTTTGCCAGCTTT
TCCTCCCTTGGGTTCTGATATTGCCGCACTAGAGGATATAGGAGAGGAAAAGTAAGGTGCAGTTGCCCCAACCTCAGACTTACCAGGAAG
CAGATACATATGAGTGTGGAAGCCGGAGGGTGTTTATGTAAGAGCACCTTCCTCACTTCCATACAGCTCTACGCGGCAAATTAACTTGAG
TTTTATTTATCTTATCCTCTGGTTTAATTACATAAATATTTATTTTTTAAGTGTAATTTTGCCAAATAATAAAAACAGAAGGAAATTGAG
ATTAGAGGGAGGTGTTTAAAGAGAGGTTATAGAGTAAAAGATTTGATGCTGGAGAGGTTAAGGTGCAATAAGAATTCAGGGAGAAATGTT
GTTCATTATTGGAGGGTAAATGATGTGGTGCCTGAGGTCTGTACATTACCTCTTAACAATTTCTGTCCTTCAGATGGAAACTCTTTGATT
TCTCAGAAAAGTTGTATGCCTATTTAATAAAGCTACTCATTTCCTTTGGAACTTTATCTTTAAGATAATAGTTTACATGTAGTAGTACTT
GAAATCTAGGATTATTAACTAATATGGGCATTGTAGTTAATGGCGGTTGATGGGTTCTAATTTTGGATGGAGTCCAGGGAAGAGAAAGTG
ATTTCTAGAAAGCCTGTTCCCCTCACTGGACGAAATAACTCCTTGTAGTAGTCTCATTACTTTTGAAGTAATCCCGCCACCTATCTAGTG
GGAGAGCCATCCAAATGAGAAACCTAAAATAATTGGTTCTTGGTAGAGATTCATTATTTCTCCACTTTGTTCTTTAGGAGATTTTAGGTG
TTGATTTTCTGTTTTATTTTAACTCATACCTTTAAAGGAATTCCCCAAAGAATGTTTACAGCAAACTTGGAATTTGTAACCTCAGCTCTG
GGAGAGGATTTTTTTCTGAGCGATTATTATCTAAAGTGTGTTGTTGCTTTAGGCTCACGGCACGCTTGCGTATGTCTGTTACCATGTCAC
TGTGGTCCTATGCCGAATGCCCTCAGGGGACTTGAATCTTTCCAATAAACCAGGTTTAGACAGTATGAGTCAATGTGCAGTGCAGCCCAC
ACTTGAGAGGATGAATGTATGTGCACTGTCACTTTGCTCTGGGTGGAAGTATGTTATTGTTGACTTATTTTCTCTGTGTTTGTTCCTACA
GCCCCTTTTTCATATGTTGCTCAGTCTCCCTTTCCCTTCTTGGTGCTTACACATCTCAGACCCTTTAGCCAAACCCTTGCCAGTGACAGT
ATTTTGGTTCTCAGTTCTCACTGTTCCCTCTGCTCCTGGAGCCTTTGAATAAAAATGCACGTAGCTATGGAGTGGGGTTTAGCTGGAAAG
GTGGCCTTCCAACTTCACGTCAACTTCTGGCTCCTCAGTTTGGCAGTAAGGCAGGGAAGTTGTTTTCCTATTTCTCACTGAGAAGATTGT

>43436_43436_7_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000557334_SLC2A14_chr12_7985410_ENST00000340749_length(amino acids)=531AA_BP=40
MLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPS
EVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI
SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV
SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL
VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL

--------------------------------------------------------------
>43436_43436_8_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000557334_SLC2A14_chr12_7985410_ENST00000431042_length(transcript)=3581nt_BP=308nt
GATTTTCCTAGGCGGCGGCCGCGGCGGCGGAGGCAGCAGCGGCGGCGGCAGTGGCGGCGGCGAAGGTGGCGGCGGCTCGGCCAGTACTCC
CGGCCCCCGCCATTTCGGACTGGGAGCGAGCGCGGCGCAGGCACTGAAGGCGGCGGCGGGGCCAGAGGCTCAGCGGCTCCCAGGTGCGGG
AGAGAGGCCTGCTGAAAATGACTGAATATAAACTTGTGGTAGTTGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTC
AGAATCATTTTGTGGACGAATATGATCCAACAATAGAGGTCACCCCAGCTCTGATCTTTGCCATCACAGTTGCTACAATCGGCTCTTTCC
AGTTTGGCTACAACACTGGGGTCATCAATGCTCCTGAGACGATCATAAAGGAATTTATCAATAAAACTTTGACGGACAAGGCAAATGCCC
CTCCCTCTGAGGTGCTGCTCACGAATCTCTGGTCCTTGTCTGTGGCCATATTTTCCGTCGGGGGTATGATCGGCTCCTTTTCCGTCGGAC
TCTTTGTTAACCGCTTTGGCAGGCGCAATTCAATGCTGATTGTCAACCTGTTGGCTGCCACTGGTGGCTGCCTTATGGGACTGTGTAAAA
TAGCTGAGTCAGTTGAAATGCTGATCCTGGGCCGCTTGGTTATTGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCCCATGTACATTG
GAGAGATCTCGCCTACTGCCCTGAGGGGTGCCTTTGGCACTCTCAACCAGCTGGGCATAGTTATTGGAATTCTGGTGGCCCAGATCTTTG
GTCTGGAACTCATCCTTGGGTCTGAAGAGCTATGGCCGGTGCTATTAGGCTTTACCATCCTTCCAGCTATCCTGCAAAGTGCAGCCCTTC
CATGTTGCCCTGAAAGTCCCAGATTTTTGCTCATTAACAGAAAAAAAGAGGAGAATGCTACGCGGATCCTCCAGCGGTTGTGGGGCACCC
AGGATGTATCCCAAGACATCCAGGAGATGAAAGATGAGAGTGCAAGGATGTCACAAGAAAAGCAAGTCACCGTGCTGGAGCTCTTTAGAG
TGTCCAGCTACCGACAGCCCATCATCATTTCCATTGTGCTCCAGCTCTCTCAGCAGCTCTCTGGGATCAATGCTGTGTTCTATTACTCAA
CAGGAATCTTCAAGGATGCAGGTGTTCAACAGCCCATCTATGCCACCATCAGCGCGGGTGTGGTTAATACTATCTTCACTTTACTTTCTC
TATTTCTGGTGGAAAGGGCAGGAAGAAGGACTCTGCATATGATAGGCCTTGGAGGGATGGCTTTTTGTTCCACGCTCATGACTGTTTCTT
TGTTATTAAAGAATCACTATAATGGGATGAGCTTTGTCTGTATTGGGGCTATCTTGGTCTTTGTGGCCTGTTTTGAAATTGGACCAGGCC
CCATTCCCTGGTTTATTGTGGCCGAACTCTTCAGCCAGGGCCCCCGCCCAGCTGCGATGGCAGTGGCCGGCTGCTCCAACTGGACCTCCA
ACTTCCTAGTCGGATTGCTCTTCCCCTCTGCTGCTTACTATTTAGGAGCCTACGTTTTTATTATCTTCACCGGCTTCCTCATTACCTTCT
TGGCCTTTACCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGACTTTTGAGGATATCACACGGGCCTTTGAAGGGCAGGCACACGGTGCAG
ATAGATCTGGGAAGGACGGCGTCATGGGGATGAACAGCATCGAGCCTGCTAAGGAGACCACCACCAATGTCTAAGTCATGCCTCCTTCCA
CCTCCCTCCCGGCATGGGAAAGCCACCTCTCCCTCAACAAGGGAGAGACTTTATCAGGATGAACCCAGGACTGCTTCTGAATGCTGCTAC
TTGATTTCTTTCTCATCCCACGCACTCCATGAGCACCCCAAGGCTGCAGTTTGTTGGATCTTCAATGGCTTTTTAAATTTTATTTCCTGG
ACATCCTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCATTTCAGGAGGGATTGGCCGCTTGGCACATGACAACTTTGCCAGCTTT
TCCTCCCTTGGGTTCTGATATTGCCGCACTAGAGGATATAGGAGAGGAAAAGTAAGGTGCAGTTGCCCCAACCTCAGACTTACCAGGAAG
CAGATACATATGAGTGTGGAAGCCGGAGGGTGTTTATGTAAGAGCACCTTCCTCACTTCCATACAGCTCTACGCGGCAAATTAACTTGAG
TTTTATTTATCTTATCCTCTGGTTTAATTACATAAATATTTATTTTTTAAGTGTAATTTTGCCAAATAATAAAAACAGAAGGAAATTGAG
ATTAGAGGGAGGTGTTTAAAGAGAGGTTATAGAGTAAAAGATTTGATGCTGGAGAGGTTAAGGTGCAATAAGAATTCAGGGAGAAATGTT
GTTCATTATTGGAGGGTAAATGATGTGGTGCCTGAGGTCTGTACATTACCTCTTAACAATTTCTGTCCTTCAGATGGAAACTCTTTGATT
TCTCAGAAAAGTTGTATGCCTATTTAATAAAGCTACTCATTTCCTTTGGAACTTTATCTTTAAGATAATAGTTTACATGTAGTAGTACTT
GAAATCTAGGATTATTAACTAATATGGGCATTGTAGTTAATGGCGGTTGATGGGTTCTAATTTTGGATGGAGTCCAGGGAAGAGAAAGTG
ATTTCTAGAAAGCCTGTTCCCCTCACTGGACGAAATAACTCCTTGTAGTAGTCTCATTACTTTTGAAGTAATCCCGCCACCTATCTAGTG
GGAGAGCCATCCAAATGAGAAACCTAAAATAATTGGTTCTTGGTAGAGATTCATTATTTCTCCACTTTGTTCTTTAGGAGATTTTAGGTG
TTGATTTTCTGTTTTATTTTAACTCATACCTTTAAAGGAATTCCCCAAAGAATGTTTACAGCAAACTTGGAATTTGTAACCTCAGCTCTG
GGAGAGGATTTTTTTCTGAGCGATTATTATCTAAAGTGTGTTGTTGCTTTAGGCTCACGGCACGCTTGCGTATGTCTGTTACCATGTCAC
TGTGGTCCTATGCCGAATGCCCTCAGGGGACTTGAATCTTTCCAATAAACCAGGTTTAGACAGTATGAGTCAATGTGCAGTGCAGCCCAC
ACTTGAGAGGATGAATGTATGTGCACTGTCACTTTGCTCTGGGTGGAAGTATGTTATTGTTGACTTATTTTCTCTGTGTTTGTTCCTACA
GCCCCTTTTTCATATGTTGCTCAGTCTCCCTTTCCCTTCTTGGTGCTTACACATCTCAGACCCTTTAGCCAAACCCTTGCCAGTGACAGT
ATTTTGGTTCTCAGTTCTCACTGTTCCCTCTGCTCCTGGAGCCTTTGAATAAAAATGCACGTAGCTATGGAGTGGGGTTTAGCTGGAAAG
GTGGCCTTCCAACTTCACGTCAACTTCTGGCTCCTCAGTTTGGCAGTAAGGCAGGGAAGTTGTTTTCCTATTTCTCACTGAGAAGATTGT

>43436_43436_8_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000557334_SLC2A14_chr12_7985410_ENST00000431042_length(amino acids)=531AA_BP=40
MLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPS
EVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI
SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV
SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL
VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL

--------------------------------------------------------------
>43436_43436_9_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000557334_SLC2A14_chr12_7985410_ENST00000543909_length(transcript)=3586nt_BP=308nt
GATTTTCCTAGGCGGCGGCCGCGGCGGCGGAGGCAGCAGCGGCGGCGGCAGTGGCGGCGGCGAAGGTGGCGGCGGCTCGGCCAGTACTCC
CGGCCCCCGCCATTTCGGACTGGGAGCGAGCGCGGCGCAGGCACTGAAGGCGGCGGCGGGGCCAGAGGCTCAGCGGCTCCCAGGTGCGGG
AGAGAGGCCTGCTGAAAATGACTGAATATAAACTTGTGGTAGTTGGAGCTGGTGGCGTAGGCAAGAGTGCCTTGACGATACAGCTAATTC
AGAATCATTTTGTGGACGAATATGATCCAACAATAGAGGTCACCCCAGCTCTGATCTTTGCCATCACAGTTGCTACAATCGGCTCTTTCC
AGTTTGGCTACAACACTGGGGTCATCAATGCTCCTGAGACGATCATAAAGGAATTTATCAATAAAACTTTGACGGACAAGGCAAATGCCC
CTCCCTCTGAGGTGCTGCTCACGAATCTCTGGTCCTTGTCTGTGGCCATATTTTCCGTCGGGGGTATGATCGGCTCCTTTTCCGTCGGAC
TCTTTGTTAACCGCTTTGGCAGGCGCAATTCAATGCTGATTGTCAACCTGTTGGCTGCCACTGGTGGCTGCCTTATGGGACTGTGTAAAA
TAGCTGAGTCAGTTGAAATGCTGATCCTGGGCCGCTTGGTTATTGGCCTCTTCTGCGGACTCTGCACAGGTTTTGTGCCCATGTACATTG
GAGAGATCTCGCCTACTGCCCTGAGGGGTGCCTTTGGCACTCTCAACCAGCTGGGCATAGTTATTGGAATTCTGGTGGCCCAGATCTTTG
GTCTGGAACTCATCCTTGGGTCTGAAGAGCTATGGCCGGTGCTATTAGGCTTTACCATCCTTCCAGCTATCCTGCAAAGTGCAGCCCTTC
CATGTTGCCCTGAAAGTCCCAGATTTTTGCTCATTAACAGAAAAAAAGAGGAGAATGCTACGCGGATCCTCCAGCGGTTGTGGGGCACCC
AGGATGTATCCCAAGACATCCAGGAGATGAAAGATGAGAGTGCAAGGATGTCACAAGAAAAGCAAGTCACCGTGCTGGAGCTCTTTAGAG
TGTCCAGCTACCGACAGCCCATCATCATTTCCATTGTGCTCCAGCTCTCTCAGCAGCTCTCTGGGATCAATGCTGTGTTCTATTACTCAA
CAGGAATCTTCAAGGATGCAGGTGTTCAACAGCCCATCTATGCCACCATCAGCGCGGGTGTGGTTAATACTATCTTCACTTTACTTTCTC
TATTTCTGGTGGAAAGGGCAGGAAGAAGGACTCTGCATATGATAGGCCTTGGAGGGATGGCTTTTTGTTCCACGCTCATGACTGTTTCTT
TGTTATTAAAGAATCACTATAATGGGATGAGCTTTGTCTGTATTGGGGCTATCTTGGTCTTTGTGGCCTGTTTTGAAATTGGACCAGGCC
CCATTCCCTGGTTTATTGTGGCCGAACTCTTCAGCCAGGGCCCCCGCCCAGCTGCGATGGCAGTGGCCGGCTGCTCCAACTGGACCTCCA
ACTTCCTAGTCGGATTGCTCTTCCCCTCTGCTGCTTACTATTTAGGAGCCTACGTTTTTATTATCTTCACCGGCTTCCTCATTACCTTCT
TGGCCTTTACCTTCTTCAAAGTCCCTGAGACCCGTGGCAGGACTTTTGAGGATATCACACGGGCCTTTGAAGGGCAGGCACACGGTGCAG
ATAGATCTGGGAAGGACGGCGTCATGGGGATGAACAGCATCGAGCCTGCTAAGGAGACCACCACCAATGTCTAAGTCATGCCTCCTTCCA
CCTCCCTCCCGGCATGGGAAAGCCACCTCTCCCTCAACAAGGGAGAGACTTTATCAGGATGAACCCAGGACTGCTTCTGAATGCTGCTAC
TTGATTTCTTTCTCATCCCACGCACTCCATGAGCACCCCAAGGCTGCAGTTTGTTGGATCTTCAATGGCTTTTTAAATTTTATTTCCTGG
ACATCCTCTTCTGCTTAGGAGAGACCGAGTGAACCTACCTTCATTTCAGGAGGGATTGGCCGCTTGGCACATGACAACTTTGCCAGCTTT
TCCTCCCTTGGGTTCTGATATTGCCGCACTAGAGGATATAGGAGAGGAAAAGTAAGGTGCAGTTGCCCCAACCTCAGACTTACCAGGAAG
CAGATACATATGAGTGTGGAAGCCGGAGGGTGTTTATGTAAGAGCACCTTCCTCACTTCCATACAGCTCTACGCGGCAAATTAACTTGAG
TTTTATTTATCTTATCCTCTGGTTTAATTACATAAATATTTATTTTTTAAGTGTAATTTTGCCAAATAATAAAAACAGAAGGAAATTGAG
ATTAGAGGGAGGTGTTTAAAGAGAGGTTATAGAGTAAAAGATTTGATGCTGGAGAGGTTAAGGTGCAATAAGAATTCAGGGAGAAATGTT
GTTCATTATTGGAGGGTAAATGATGTGGTGCCTGAGGTCTGTACATTACCTCTTAACAATTTCTGTCCTTCAGATGGAAACTCTTTGATT
TCTCAGAAAAGTTGTATGCCTATTTAATAAAGCTACTCATTTCCTTTGGAACTTTATCTTTAAGATAATAGTTTACATGTAGTAGTACTT
GAAATCTAGGATTATTAACTAATATGGGCATTGTAGTTAATGGCGGTTGATGGGTTCTAATTTTGGATGGAGTCCAGGGAAGAGAAAGTG
ATTTCTAGAAAGCCTGTTCCCCTCACTGGACGAAATAACTCCTTGTAGTAGTCTCATTACTTTTGAAGTAATCCCGCCACCTATCTAGTG
GGAGAGCCATCCAAATGAGAAACCTAAAATAATTGGTTCTTGGTAGAGATTCATTATTTCTCCACTTTGTTCTTTAGGAGATTTTAGGTG
TTGATTTTCTGTTTTATTTTAACTCATACCTTTAAAGGAATTCCCCAAAGAATGTTTACAGCAAACTTGGAATTTGTAACCTCAGCTCTG
GGAGAGGATTTTTTTCTGAGCGATTATTATCTAAAGTGTGTTGTTGCTTTAGGCTCACGGCACGCTTGCGTATGTCTGTTACCATGTCAC
TGTGGTCCTATGCCGAATGCCCTCAGGGGACTTGAATCTTTCCAATAAACCAGGTTTAGACAGTATGAGTCAATGTGCAGTGCAGCCCAC
ACTTGAGAGGATGAATGTATGTGCACTGTCACTTTGCTCTGGGTGGAAGTATGTTATTGTTGACTTATTTTCTCTGTGTTTGTTCCTACA
GCCCCTTTTTCATATGTTGCTCAGTCTCCCTTTCCCTTCTTGGTGCTTACACATCTCAGACCCTTTAGCCAAACCCTTGCCAGTGACAGT
ATTTTGGTTCTCAGTTCTCACTGTTCCCTCTGCTCCTGGAGCCTTTGAATAAAAATGCACGTAGCTATGGAGTGGGGTTTAGCTGGAAAG
GTGGCCTTCCAACTTCACGTCAACTTCTGGCTCCTCAGTTTGGCAGTAAGGCAGGGAAGTTGTTTTCCTATTTCTCACTGAGAAGATTGT

>43436_43436_9_KRAS-SLC2A14_KRAS_chr12_25398208_ENST00000557334_SLC2A14_chr12_7985410_ENST00000543909_length(amino acids)=531AA_BP=40
MLKMTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEVTPALIFAITVATIGSFQFGYNTGVINAPETIIKEFINKTLTDKANAPPS
EVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEI
SPTALRGAFGTLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINRKKEENATRILQRLWGTQDV
SQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFL
VERAGRRTLHMIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFL

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for KRAS-SLC2A14

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for KRAS-SLC2A14

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for KRAS-SLC2A14

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source