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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LAMA3-OSBPL1A (FusionGDB2 ID:43877)

Fusion Gene Summary for LAMA3-OSBPL1A

check button Fusion gene summary
Fusion gene informationFusion gene name: LAMA3-OSBPL1A
Fusion gene ID: 43877
HgeneTgene
Gene symbol

LAMA3

OSBPL1A

Gene ID

3910

114876

Gene namelaminin subunit alpha 4oxysterol binding protein like 1A
SynonymsCMD1JJ|LAMA3|LAMA4*-1ORP-1|ORP1|OSBPL1B
Cytomap

6q21

18q11.2

Type of geneprotein-codingprotein-coding
Descriptionlaminin subunit alpha-4laminin alpha 4 chainlaminin, alpha 4oxysterol-binding protein-related protein 1OSBP-related protein 1oxysterol binding protein-like 1Boxysterol-binding protein-related protein 1 variant 1oxysterol-binding protein-related protein 1 variant 2
Modification date2020031320200313
UniProtAcc

Q16787

.
Ensembl transtripts involved in fusion geneENST00000588770, ENST00000269217, 
ENST00000313654, ENST00000399516, 
ENST00000587184, 		ENST00000319481, 
ENST00000357041, ENST00000399441, 
ENST00000399443, ENST00000582618, 
Fusion gene scores* DoF score28 X 24 X 10=672018 X 15 X 10=2700
# samples 3319
** MAII scorelog2(33/6720*10)=-4.34792330342031
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(19/2700*10)=-3.82888808360725
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LAMA3 [Title/Abstract] AND OSBPL1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLAMA3(21513899)-OSBPL1A(21892070), # samples:4
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across LAMA3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across OSBPL1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-IN-A7NU-01ALAMA3chr18

21513899

-OSBPL1Achr18

21892070

-
ChimerDB4STADTCGA-IN-A7NU-01ALAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
ChimerDB4STADTCGA-IN-A7NULAMA3chr18

21513899

+OSBPL1Achr18

21892070

-


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Fusion Gene ORF analysis for LAMA3-OSBPL1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000588770ENST00000319481LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
3UTR-intronENST00000588770ENST00000357041LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
3UTR-intronENST00000588770ENST00000399441LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
3UTR-intronENST00000588770ENST00000399443LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
3UTR-intronENST00000588770ENST00000582618LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000269217ENST00000357041LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000269217ENST00000399441LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000269217ENST00000399443LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000269217ENST00000582618LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000313654ENST00000357041LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000313654ENST00000399441LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000313654ENST00000399443LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000313654ENST00000582618LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000399516ENST00000357041LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000399516ENST00000399441LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000399516ENST00000399443LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000399516ENST00000582618LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000587184ENST00000357041LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000587184ENST00000399441LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000587184ENST00000399443LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
5CDS-intronENST00000587184ENST00000582618LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
In-frameENST00000269217ENST00000319481LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
In-frameENST00000313654ENST00000319481LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
In-frameENST00000399516ENST00000319481LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-
In-frameENST00000587184ENST00000319481LAMA3chr18

21513899

+OSBPL1Achr18

21892070

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000313654LAMA3chr1821513899+ENST00000319481OSBPL1Achr1821892070-121229103241109863581
ENST00000399516LAMA3chr1821513899+ENST00000319481OSBPL1Achr1821892070-1171386940105773525
ENST00000269217LAMA3chr1821513899+ENST00000319481OSBPL1Achr1821892070-7259424020561231972
ENST00000587184LAMA3chr1821513899+ENST00000319481OSBPL1Achr1821892070-68863867057501916

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000313654ENST00000319481LAMA3chr1821513899+OSBPL1Achr1821892070-0.0004734040.9995266
ENST00000399516ENST00000319481LAMA3chr1821513899+OSBPL1Achr1821892070-0.000334320.99966574
ENST00000269217ENST00000319481LAMA3chr1821513899+OSBPL1Achr1821892070-0.0006362190.99936384
ENST00000587184ENST00000319481LAMA3chr1821513899+OSBPL1Achr1821892070-0.0004927820.9995072

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Fusion Genomic Features for LAMA3-OSBPL1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LAMA3-OSBPL1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr18:21513899/chr18:21892070)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LAMA3

Q16787

.
FUNCTION: Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.; FUNCTION: Laminin-5 is thought to be involved in (1) cell adhesion via integrin alpha-3/beta-1 in focal adhesion and integrin alpha-6/beta-4 in hemidesmosomes, (2) signal transduction via tyrosine phosphorylation of pp125-FAK and p80, (3) differentiation of keratinocytes.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751852_194129543334.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751987_216929543334.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67752322_238829543334.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741852_194128983278.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741987_216928983278.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66742322_238828983278.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751266_131129543334.0DomainLaminin EGF-like 9
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751312_135529543334.0DomainLaminin EGF-like 10
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751356_140429543334.0DomainLaminin EGF-like 11
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751405_145529543334.0DomainLaminin EGF-like 12
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751476_165329543334.0DomainLaminin IV type A
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751687_173329543334.0DomainLaminin EGF-like 13
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751734_178629543334.0DomainLaminin EGF-like 14
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751787_182129543334.0DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67752390_259129543334.0DomainLaminin G-like 1
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67752598_276029543334.0DomainLaminin G-like 2
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67752767_292729543334.0DomainLaminin G-like 3
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775299_35529543334.0DomainLaminin EGF-like 1
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775356_42529543334.0DomainLaminin EGF-like 2
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775426_46929543334.0DomainLaminin EGF-like 3
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+677543_29829543334.0DomainLaminin N-terminal
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775491_53529543334.0DomainLaminin EGF-like 4
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775536_58829543334.0DomainLaminin EGF-like 5
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775590_63029543334.0DomainLaminin EGF-like 6
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775631_68329543334.0DomainLaminin EGF-like 7
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775684_72829543334.0DomainLaminin EGF-like 8
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741266_131128983278.0DomainLaminin EGF-like 9
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741312_135528983278.0DomainLaminin EGF-like 10
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741356_140428983278.0DomainLaminin EGF-like 11
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741405_145528983278.0DomainLaminin EGF-like 12
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741476_165328983278.0DomainLaminin IV type A
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741687_173328983278.0DomainLaminin EGF-like 13
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741734_178628983278.0DomainLaminin EGF-like 14
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741787_182128983278.0DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66742390_259128983278.0DomainLaminin G-like 1
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66742598_276028983278.0DomainLaminin G-like 2
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674299_35528983278.0DomainLaminin EGF-like 1
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674356_42528983278.0DomainLaminin EGF-like 2
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674426_46928983278.0DomainLaminin EGF-like 3
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+667443_29828983278.0DomainLaminin N-terminal
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674491_53528983278.0DomainLaminin EGF-like 4
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674536_58828983278.0DomainLaminin EGF-like 5
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674590_63028983278.0DomainLaminin EGF-like 6
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674631_68328983278.0DomainLaminin EGF-like 7
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674684_72828983278.0DomainLaminin EGF-like 8
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937299_35512891669.0DomainLaminin EGF-like 1
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937356_42512891669.0DomainLaminin EGF-like 2
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937426_46912891669.0DomainLaminin EGF-like 3
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+293743_29812891669.0DomainLaminin N-terminal
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937491_53512891669.0DomainLaminin EGF-like 4
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937536_58812891669.0DomainLaminin EGF-like 5
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937590_63012891669.0DomainLaminin EGF-like 6
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937631_68312891669.0DomainLaminin EGF-like 7
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937684_72812891669.0DomainLaminin EGF-like 8
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67752278_228029543334.0MotifCell attachment site
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66742278_228028983278.0MotifCell attachment site
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751266_146529543334.0RegionNote=Domain III B
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751654_182129543334.0RegionNote=Domain III A
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67751822_238929543334.0RegionNote=Domain II and I
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775298_72829543334.0RegionNote=Domain V
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+6775796_126529543334.0RegionNote=Domain IV 1 (domain IV B)
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741266_146528983278.0RegionNote=Domain III B
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741654_182128983278.0RegionNote=Domain III A
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66741822_238928983278.0RegionNote=Domain II and I
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674298_72828983278.0RegionNote=Domain V
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+6674796_126528983278.0RegionNote=Domain IV 1 (domain IV B)
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937298_72812891669.0RegionNote=Domain V
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+2937796_126512891669.0RegionNote=Domain IV 1 (domain IV B)
TgeneOSBPL1Achr18:21513899chr18:21892070ENST000003194811128430_463323951.0Coiled coilOntology_term=ECO:0000255
TgeneOSBPL1Achr18:21513899chr18:21892070ENST000003194811128877_913323951.0Coiled coilOntology_term=ECO:0000255
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000357041016430_4630569.0Coiled coilOntology_term=ECO:0000255
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000357041016877_9130569.0Coiled coilOntology_term=ECO:0000255
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000399443014430_4630438.0Coiled coilOntology_term=ECO:0000255
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000399443014877_9130438.0Coiled coilOntology_term=ECO:0000255
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000357041016235_3340569.0DomainPH
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000399443014235_3340438.0DomainPH
TgeneOSBPL1Achr18:21513899chr18:21892070ENST000003194811128469_483323951.0MotifFFAT
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000357041016469_4830569.0MotifFFAT
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000399443014469_4830438.0MotifFFAT
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000357041016175_2040569.0RepeatNote=ANK 3
TgeneOSBPL1Achr18:21513899chr18:21892070ENST0000035704101647_760569.0RepeatNote=ANK 1
TgeneOSBPL1Achr18:21513899chr18:21892070ENST0000035704101680_1090569.0RepeatNote=ANK 2
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000399443014175_2040438.0RepeatNote=ANK 3
TgeneOSBPL1Achr18:21513899chr18:21892070ENST0000039944301447_760438.0RepeatNote=ANK 1
TgeneOSBPL1Achr18:21513899chr18:21892070ENST0000039944301480_1090438.0RepeatNote=ANK 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371852_194112891669.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371987_216912891669.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29372322_238812891669.0Coiled coilOntology_term=ECO:0000255
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67752986_315029543334.0DomainLaminin G-like 4
HgeneLAMA3chr18:21513899chr18:21892070ENST00000313654+67753157_333029543334.0DomainLaminin G-like 5
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66742767_292728983278.0DomainLaminin G-like 3
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66742986_315028983278.0DomainLaminin G-like 4
HgeneLAMA3chr18:21513899chr18:21892070ENST00000399516+66743157_333028983278.0DomainLaminin G-like 5
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371266_131112891669.0DomainLaminin EGF-like 9
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371312_135512891669.0DomainLaminin EGF-like 10
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371356_140412891669.0DomainLaminin EGF-like 11
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371405_145512891669.0DomainLaminin EGF-like 12
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371476_165312891669.0DomainLaminin IV type A
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371687_173312891669.0DomainLaminin EGF-like 13
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371734_178612891669.0DomainLaminin EGF-like 14
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371787_182112891669.0DomainLaminin EGF-like 15%3B truncated
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29372390_259112891669.0DomainLaminin G-like 1
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29372598_276012891669.0DomainLaminin G-like 2
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29372767_292712891669.0DomainLaminin G-like 3
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29372986_315012891669.0DomainLaminin G-like 4
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29373157_333012891669.0DomainLaminin G-like 5
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29372278_228012891669.0MotifCell attachment site
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371266_146512891669.0RegionNote=Domain III B
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371654_182112891669.0RegionNote=Domain III A
HgeneLAMA3chr18:21513899chr18:21892070ENST00000587184+29371822_238912891669.0RegionNote=Domain II and I
TgeneOSBPL1Achr18:21513899chr18:21892070ENST000003194811128235_334323951.0DomainPH
TgeneOSBPL1Achr18:21513899chr18:21892070ENST000003194811128175_204323951.0RepeatNote=ANK 3
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000319481112847_76323951.0RepeatNote=ANK 1
TgeneOSBPL1Achr18:21513899chr18:21892070ENST00000319481112880_109323951.0RepeatNote=ANK 2


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Fusion Gene Sequence for LAMA3-OSBPL1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>43877_43877_1_LAMA3-OSBPL1A_LAMA3_chr18_21513899_ENST00000269217_OSBPL1A_chr18_21892070_ENST00000319481_length(transcript)=7259nt_BP=4240nt
AATTACAGAGCGGTGCGCTTACCTGCGGGACTGTTATGTGCGCTCTGGCACAGGCTGACTCATGTGTGAAGTTTAAAGGTGGGGCCCCTG
CCGCAGACAGCCTTCCTCACCTGAGTCAGGCAGGCCCGGGCACTGAGCAGGAAGGGCAGGTATAAGAGGAAGAGGCAGAGGTTCCTGCGC
AGCCAGCGGACGTCCAGGAACCGGGATGCCTCCAGCAGTGAGGCGGTCAGCCTGCAGCATGGGATGGCTGTGGATCTTTGGGGCAGCCCT
GGGGCAGTGTCTGGGCTACAGTTCACAGCAGCAAAGGGTGCCATTTCTTCAGCCTCCCGGTCAAAGTCAACTGCAAGCGAGTTATGTGGA
GTTTAGACCCAGCCAGGGTTGTAGCCCTGGATACTATCGGGATCATAAAGGCTTGTATACCGGACGGTGTGTTCCCTGCAATTGCAACGG
ACATTCAAATCAATGCCAGGATGGCTCAGGCATATGTGTTAACTGTCAGCACAACACCGCGGGAGAGCACTGTGAACGCTGCCAGGAGGG
CTACTATGGCAACGCCGTCCACGGATCCTGCAGGGCCTGCCCATGTCCTCACACTAACAGCTTTGCCACTGGCTGTGTGGTGAATGGGGG
AGACGTGCGGTGCTCCTGCAAAGCTGGGTACACAGGAACACAGTGTGAAAGGTGTGCACCGGGATATTTCGGGAATCCCCAGAAATTCGG
AGGTAGCTGCCAACCATGCAGTTGTAACAGCAATGGCCAGCTGGGCAGCTGTCATCCCCTGACTGGAGACTGCATAAACCAAGAACCCAA
AGATAGCAGCCCTGCAGAAGAATGTGATGATTGCGACAGCTGTGTGATGACCCTCCTGAACGACCTGGCCACCATGGGCGAGCAGCTCCG
CCTGGTCAAGTCTCAGCTGCAGGGCCTGAGTGCCAGCGCAGGGCTTCTGGAGCAGATGAGGCACATGGAGACCCAGGCCAAGGACCTGAG
GAATCAGTTGCTCAACTACCGTTCTGCCATTTCAAATCATGGATCAAAAATAGAAGGCCTGGAAAGAGAACTGACTGATTTGAATCAAGA
ATTTGAGACTTTGCAAGAAAAGGCTCAAGTAAATTCCAGAAAAGCACAAACATTAAACAACAATGTTAATCGGGCAACACAAAGCGCAAA
AGAACTGGATGTGAAGATTAAAAATGTCATCCGGAATGTGCACATTCTTTTAAAGCAGATCTCTGGGACAGATGGAGAGGGAAACAACGT
GCCTTCAGGTGACTTTTCCAGAGAGTGGGCTGAAGCCCAGCGCATGATGAGGGAACTGCGGAACAGGAACTTTGGAAAGCACCTCAGAGA
AGCAGAAGCTGATAAAAGGGAGTCGCAGCTCTTGCTGAACCGGATAAGGACCTGGCAGAAAACCCACCAGGGGGAGAACAATGGGCTTGC
TAACAGTATCCGGGATTCTTTAAATGAATACGAAGCCAAACTCAGTGACCTTCGTGCTCGGCTGCAGGAGGCAGCTGCCCAAGCCAAGCA
GGCAAATGGCTTGAACCAAGAAAACGAGAGAGCTTTGGGAGCCATTCAGAGACAAGTGAAAGAAATAAATTCCCTGCAGAGTGATTTCAC
CAAGTATCTAACCACTGCAGACTCATCTTTGTTGCAAACCAACATTGCGCTGCAGCTGATGGAGAAAAGCCAGAAGGAATATGAAAAATT
AGCTGCCAGTTTAAATGAAGCAAGACAAGAACTAAGTGACAAAGTAAGAGAACTTTCCAGATCTGCTGGCAAAACATCCCTTGTGGAGGA
GGCAGAAAAGCACGCGCGGTCCTTACAAGAGCTGGCAAAGCAGCTGGAAGAGATCAAGAGAAACGCCAGCGGGGATGAGCTGGTGCGCTG
TGCTGTGGATGCCGCCACCGCCTACGAGAACATCCTCAATGCCATCAAAGCGGCCGAGGACGCAGCCAACAGGGCTGCCAGTGCATCTGA
ATCTGCCCTCCAGACAGTGATAAAGGAAGATCTGCCAAGAAAAGCTAAAACCCTGAGTTCCAACAGTGATAAACTGTTAAATGAAGCCAA
GATGACACAAAAGAAGCTAAAGCAAGAAGTCAGTCCAGCTCTCAACAACCTACAGCAAACCCTGAATATTGTGACAGTTCAGAAAGAAGT
GATAGACACCAATCTCACAACTCTCCGAGATGGTCTTCATGGGATACAGAGAGGTGATATTGATGCTATGATCAGTAGTGCAAAGAGCAT
GGTCAGAAAGGCCAACGACATCACAGATGAGGTTCTGGATGGGCTCAACCCCATCCAGACAGATGTGGAAAGAATTAAGGACACCTATGG
GAGGACACAGAACGAAGACTTCAAAAAGGCTCTGACTGATGCAGATAACTCGGTGAATAAGTTAACCAACAAACTACCTGATCTTTGGCG
CAAGATTGAAAGTATCAACCAACAGCTGTTGCCCTTGGGAAACATCTCTGACAACATGGACAGAATACGAGAACTAATTCAGCAGGCCAG
AGATGCTGCCAGTAAGGTTGCTGTCCCCATGAGGTTCAATGGTAAATCTGGAGTCGAAGTCCGACTGCCAAATGACCTGGAAGATTTGAA
AGGATATACATCTCTGTCCTTGTTTCTCCAAAGGCCCAACTCAAGAGAAAATGGGGGTACTGAGAATATGTTTGTGATGTACCTTGGAAA
TAAAGATGCCTCCCGGGACTACATCGGCATGGCAGTTGTGGATGGCCAGCTCACCTGTGTCTACAACCTGGGGGACCGTGAGGCTGAACT
CCAAGTGGACCAGATCTTGACCAAGAGTGAGACTAAGGAGGCAGTTATGGATCGGGTGAAATTTCAGAGAATTTATCAGTTTGCAAGGCT
TAATTACACCAAAGGAGCCACATCCAGTAAACCAGAAACACCCGGAGTCTATGACATGGATGGTAGAAATAGCAATACACTCCTTAATTT
GGATCCTGAAAATGTTGTATTTTATGTTGGAGGTTACCCACCTGATTTTAAACTTCCCAGTCGACTAAGTTTCCCTCCATACAAAGGTTG
TATTGAATTAGATGACCTCAATGAAAATGTTCTGAGCTTGTACAACTTCAAAAAAACATTCAATCTCAACACAACTGAAGTGGAGCCTTG
TAGAAGGAGGAAGGAAGAGTCAGACAAAAATTATTTTGAAGGTACGGGCTATGCTCGAGTTCCAACTCAACCACATGCTCCCATCCCAAC
CTTTGGACAGACAATTCAGACCACCGTGGATAGAGGCTTGCTGTTCTTTGCAGAAAACGGGGATCGCTTCATATCTCTAAATATAGAAGA
TGGCAAGCTCATGGTGAGATACAAACTGAATTCAGAGCTACCAAAAGAGAGAGGAGTTGGAGACGCCATAAACAACGGCAGAGACCATTC
GATTCAGATCAAAATTGGAAAACTCCAAAAGCGTATGTGGATAAATGTGGACGTTCAAAACACTATAATTGATGGTGAAGTATTTGATTT
CAGCACATATTATCTGGGAGGAATTCCAATTGCAATCAGGGAAAGATTTAACATTTCTACGCCTGCTTTCCGAGGCTGCATGAAAAATTT
GAAGAAAACCAGTGGTGTCGTTAGATTGAATGATACTGTGGGAGTAACCAAAAAGTGCTCGGAAGACTGGAAGCTTGTGCGATCTGCCTC
ATTCTCCAGAGGAGGACAATTGAGTTTCACTGATTTGGGCTTACCACCTACTGACCACCTCCAGGCCTCATTTGGATTTCAGACCTTTCA
ACCCAGTGGCATATTATTAGATCATCAGACATGGACAAGGAACCTGCAGGTCACTCTGGAAGATGGTTACATTGAATTGAGCACCAGCGA
TAGCGGCAGCCCAATTTTTAAATCTCCACAGACGTATATGGATGGTTTACTGCATTATGTATCTGTAATAAGCGACAACTCTGGACTACG
GCTTCTCATCGATGACCAGCTTCTGAGAAATAGCAAAAGGCTAAAACACATTTCAAGTTCCCGGCAGTCTCTGCGTCTGGGCGGGAGCAA
TTTTGAGGGTTGTATTAGCAATGTTTTTGTCCAGAGGTTATCACTGAGTCCTGAAGTCCTAGATTTGACCAGTAACTCTCTCAAGAGAGA
TGTGTCCCTGGGAGGCTGCAGTTTAAACAAACCACCTTTTCTAATGTTGCTTAAAGGTTCTACCAGGTTTAACAAGACCAAGACTTTTCG
TATCAACCAGGACTGGCTGGAAGCAATAGAAGAACATTCTGCTTACAGCACTCACTACTGTTCCCAGGACCAGCTGACTGATGAGGAGGA
GGAAGATACGGTTTCTGCTGCAGACCTGAAGAAATCATTAGAGAAAGCACAGTCATGCCAACAGCGACTAGATAGGGAAATTTCCAACTT
TCTCAAAATGATTAAGGAGTGTGACATGGCTAAAGAAATGCTTCCATCATTTCTTCAGAAAGTTGAAGTTGTCTCAGAAGCTTCTAGAGA
AACTTGTGTAGCTTTGACTGATTGCCTTAATCTCTTCACCAAACAAGAAGGGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAAAA
CAAAATCTTGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGCAT
CCTTAGCGAGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCCTT
TGAAGAGGAAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGCAT
CAAGAAACACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATGGA
ACTATCCAAGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTCAT
CCACAAGGCCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAACG
GACTGGAAAACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTCAG
CCATCACCCACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTCTG
GGGGAAGAGTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACCTG
CTGTGTGCATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGTGT
GTTGAATTTTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGTGC
CCTCTATGGGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAAGA
GAAGAAGAACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGAAG
CGTTCTTCTATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTAGA
CAAAGACATGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCTAG
TGAAGAAAAAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTCCA
TCAAGGTCCTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATTTA
TTAAAATGCATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACTTA
TCTTTTAAAAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAAAG
TCTTAGGAAAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATATG
CTTTTTATGGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATCAA
GTTATTTTGAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTTAT
TCTCAGATATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTCCA
TCTTCCAAGAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTCAT
TTACTTAGTGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTATA
AAATCTAGCAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCCAG
TGGCAAATGCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAGTA
CCTGTGTACTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTATTT
ATCCACCCAAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACAAG

>43877_43877_1_LAMA3-OSBPL1A_LAMA3_chr18_21513899_ENST00000269217_OSBPL1A_chr18_21892070_ENST00000319481_length(amino acids)=1972AA_BP=1344
MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDG
SGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC
NSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRS
AISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSRE
WAEAQRMMRELRNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQEN
ERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSL
QELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQ
EVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFK
KALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLF
LQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATS
SKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESD
KNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKL
QKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLS
FTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLL
RNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQDWLEA
IEEHSAYSTHYCSQDQLTDEEEEDTVSAADLKKSLEKAQSCQQRLDREISNFLKMIKECDMAKEMLPSFLQKVEVVSEASRETCVALTDC
LNLFTKQEGVRNFKLEQEQEKNKILSEALETLATEHHELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLG
SRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSD
PVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEP
KGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTEC
LYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIP

--------------------------------------------------------------
>43877_43877_2_LAMA3-OSBPL1A_LAMA3_chr18_21513899_ENST00000313654_OSBPL1A_chr18_21892070_ENST00000319481_length(transcript)=12122nt_BP=9103nt
GAGCGCTGTCAGTTCCTGATCCGGCTGGTGCCCGCTCCAGCCGCGGCAGGTTCCAGAGCTGAGAGGCCACCCCCACGCCGCGGGCTTCCA
GCGCGTGGAGCAAGGGGAGCGGCCCCGGCGCCGCCCATATCCCCGGCTGCGCTAGTCCTGGCGCTGCAGGTCCGGGAGGCGCAGGCGGAG
AGCGGCGGTGCCCCCGAGCCCCTCTGCGGACGGCTCAGGCGGGAGGACCCCGCGCGGCTGGATGGCGGCGGCCGCGCGGCCTCGGGGTCG
GGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCAGCCTGCGGGGCGACCGCTCGGGATCCCGG
GGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATTTGGGCCACCGCCACCTGCGGGGAGAGGGG
ACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCCCCAGGCAGCGGCCACACCATCCAGGGCCA
GTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATCGATGGATCTGAACGTTGGTGGCAAAGCCC
TCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGCTCTTCCATGTGGCCTATATTTTAATCAAATT
TGCAAATTCTCCTCGCCCTGATCTTTGGGTCTTGGAAAGATCTGTAGACTTTGGAAGCACCTACTCACCATGGCAATATTTTGCTCATTC
TAAAGTAGACTGTTTAAAAGAATTTGGGCGGGAGGCAAATATGGCTGTCACCCGGGATGATGATGTACTTTGTGTTACTGAATATTCCCG
TATTGTACCTTTGGAAAATGGTGAGGTTGTGGTGTCCTTGATAAACGGTCGTCCAGGTGCAAAAAATTTTACTTTCTCTCACACCCTGAG
GGAGTTTACCAAGGCAACAAACATCCGCTTGCGTTTTCTTAGAACCAATACGCTTCTTGGACACCTCATCTCCAAAGCCCAGCGAGATCC
AACTGTCACTCGGCGGTATTATTACAGCATAAAGGACATCAGCATTGGTGGGCAGTGTGTTTGCAATGGCCATGCTGAAGTGTGCAATAT
AAACAATCCTGAAAAACTGTTTCGGTGTGAATGCCAGCACCACACCTGTGGGGAGACGTGTGATCGCTGCTGCACAGGGTACAATCAGAG
GCGCTGGCGGCCCGCCGCTTGGGAGCAGAGCCACGAGTGTGAAGCATGCAACTGCCACGGCCATGCCAGCAACTGTTACTATGATCCAGA
TGTTGAGCGGCAGCAGGCAAGCTTGAATACCCAGGGCATCTATGCTGGTGGAGGGGTCTGCATTAACTGTCAGCACAACACAGCTGGAGT
AAACTGTGAACAGTGTGCTAAGGGCTATTACCGCCCTTATGGGGTTCCAGTGGATGCCCCTGATGGCTGCATCCCCTGCAGCTGTGACCC
TGAGCATGCGGATGGCTGTGAACAGGGTTCAGGCCGCTGTCACTGCAAGCCAAATTTCCACGGAGACAACTGTGAGAAGTGTGCAATTGG
ATACTACAATTTCCCATTTTGCTTGAGAATTCCCATTTTTCCTGTTTCTACACCAAGTTCAGAAGATCCAGTAGCTGGAGATATAAAAGG
GTGTGACTGTAATCTGGAAGGTGTTCTCCCTGAAATATGTGATGCCCACGGACGGTGCCTGTGCCGCCCTGGGGTTGAGGGCCCTCGATG
TGATACCTGCCGCTCTGGTTTCTACTCATTCCCTATTTGCCAAGCCTGCTGGTGTTCAGCCCTTGGATCCTACCAGATGCCCTGCAGCTC
AGTGACTGGACAGTGTGAATGTCGGCCAGGAGTTACAGGACAGCGGTGTGACAGGTGTCTCTCAGGAGCTTATGATTTCCCCCACTGCCA
AGGTTCCAGCAGTGCTTGTGACCCAGCTGGTACCATCAACTCCAATTTGGGGTATTGCCAATGCAAGCTTCATGTTGAAGGTCCTACTTG
TAGCCGCTGCAAACTGTTATATTGGAATCTGGACAAAGAAAACCCCAGTGGATGTTCAGAATGCAAGTGCCATAAGGCGGGAACAGTGAG
TGGAACTGGAGAGTGTAGGCAGGGAGATGGTGACTGTCACTGCAAGTCCCATGTGGGTGGCGATTCCTGCGACACCTGTGAAGATGGATA
TTTTGCTTTGGAAAAGAGCAATTACTTTGGGTGTCAAGGGTGTCAGTGTGACATTGGTGGGGCATTGTCCTCCATGTGCAGTGGGCCCTC
GGGAGTGTGCCAGTGCCGAGAGCATGTCGTGGGAAAGGTGTGCCAGCGGCCTGAAAACAACTACTATTTCCCAGATTTGCATCATATGAA
GTATGAGATTGAAGACGGCAGCACACCTAATGGGAGAGACCTTCGATTTGGATTTGATCCGCTGGCATTTCCTGAGTTTAGCTGGAGAGG
ATATGCCCAAATGACCTCAGTACAGAATGATGTAAGAATAACATTGAATGTAGGGAAGTCAAGTGGCTCCTTGTTTCGTGTTATTCTGAG
ATACGTTAACCCTGGAACTGAAGCAGTATCTGGCCATATAACTATTTATCCATCCTGGGGTGCTGCTCAAAGCAAAGAGATCATCTTCCT
GCCGAGTAAGGAGCCAGCCTTTGTCACTGTCCCTGGAAATGGTTTTGCAGACCCATTTTCAATCACACCAGGAATATGGGTTGCTTGTAT
TAAGGCAGAAGGAGTCCTTCTGGATTACCTGGTGCTGCTCCCCAGGGACTACTATGAAGCCTCTGTACTGCAGCTGCCAGTCACAGAACC
ATGTGCCTACGCAGGACCTCCCCAAGAAAATTGCTTACTCTACCAGCATTTGCCAGTGACCAGATTCCCCTGTACCCTGGCTTGTGAGGC
CAGACACTTCCTGCTTGATGGGGAGCCAAGACCCGTGGCAGTGAGGCAGCCCACACCTGCACACCCTGTCATGGTGGACCTCAGCGGGAG
AGAGGTGGAATTGCATCTGCGGCTGCGCATCCCACAGGTTGGCCACTACGTGGTTGTGGTCGAGTATTCCACGGAGGCAGCTCAGCTGTT
TGTGGTTGATGTGAATGTGAAGAGCTCCGGGTCTGTTCTGGCAGGCCAGGTGAACATTTACAGCTGCAACTACAGTGTTCTCTGCCGGAG
TGCTGTGATTGATCACATGAGCCGCATCGCCATGTATGAGCTATTGGCAGATGCAGACATTCAGCTCAAGGGACACATGGCCCGATTCCT
TCTGCATCAAGTTTGTATCATACCTATTGAAGAATTCTCAGCTGAGTATGTGAGACCACAAGTCCACTGCATTGCCAGTTATGGGCGATT
TGTCAATCAAAGTGCCACCTGTGTCTCCTTGGCCCATGAAACTCCTCCAACAGCATTAATTTTGGATGTTCTAAGTGGCAGGCCTTTCCC
TCACCTGCCCCAGCAGTCGTCACCTTCTGTTGATGTTCTTCCTGGGGTCACCTTGAAGGCACCGCAGAATCAAGTGACCCTGAGAGGACG
TGTACCACACCTGGGCCGATACGTCTTTGTCATCCATTTTTACCAAGCAGCGCACCCGACGTTTCCCGCGCAGGTGTCGGTGGATGGCGG
GTGGCCACGGGCAGGCTCCTTCCATGCCTCTTTTTGCCCCCATGTGCTTGGCTGCCGGGATCAAGTGATTGCCGAAGGCCAGATTGAGTT
TGACATCTCAGAGCCTGAAGTGGCCGCAACTGTGAAGGTTCCAGAAGGAAAGTCCTTGGTTTTGGTCCGTGTTCTAGTGGTGCCTGCAGA
AAACTATGACTACCAAATACTTCACAAAAAATCCATGGACAAGTCACTCGAGTTTATCACCAATTGTGGAAAAAACAGCTTTTACCTTGA
CCCCCAGACAGCCTCCAGATTCTGTAAGAATTCCGCCAGGTCCCTGGTGGCCTTTTACCACAAGGGCGCCCTGCCTTGTGAGTGCCACCC
CACTGGGGCCACCGGCCCTCACTGCAGCCCTGAGGGTGGGCAGTGCCCATGCCAGCCCAACGTCATCGGGCGGCAGTGCACCCGCTGTGC
AACAGGCCACTACGGATTCCCACGCTGCAAGCCGTGCAGCTGTGGTCGGCGCCTTTGTGAAGAGATGACGGGGCAGTGCCGCTGCCCTCC
CCGCACGGTCAGGCCCCAGTGTGAGGTGTGTGAGACACACTCATTCAGCTTCCACCCCATGGCCGGCTGCGAAGGCTGCAACTGTTCCAG
GAGGGGCACCATCGAGGCTGCCATGCCGGAGTGTGACCGGGACAGCGGGCAGTGCAGATGCAAGCCCAGAATCACAGGGCGGCAGTGTGA
CCGATGTGCTTCCGGGTTTTACCGCTTTCCTGAGTGTGTTCCCTGCAATTGCAACAGAGATGGGACTGAGCCAGGAGTGTGTGACCCAGG
GACCGGGGCTTGCCTCTGCAAGGAAAATGTAGAAGGCACAGAGTGTAATGTGTGTCGAGAAGGCTCATTCCATTTGGACCCAGCCAATCT
CAAGGGTTGTACCAGCTGTTTCTGTTTTGGAGTAAATAATCAATGTCACAGCTCACATAAGCGAAGGACTAAGTTTGTGGATATGCTGGG
CTGGCACCTGGAGACAGCAGACAGAGTGGACATCCCTGTCTCTTTCAACCCAGGCAGCAACAGTATGGTGGCGGATCTCCAGGAGCTGCC
CGCAACCATCCACAGCGCGTCCTGGGTCGCACCCACCTCCTACCTGGGGGACAAGGTTTCTTCATATGGTGGTTACCTCACTTACCAAGC
CAAGTCCTTTGGCTTGCCTGGCGACATGGTTCTTCTGGAAAAGAAGCCGGATGTACAGCTCACTGGTCAGCACATGTCCATCATCTATGA
GGAGACAAACACCCCACGGCCAGACCGGCTGCATCATGGACGAGTGCACGTGGTCGAGGGAAACTTCAGACATGCCAGCAGCCGTGCCCC
AGTGTCTAGGGAGGAGCTGATGACAGTGCTGTCTAGACTGGCAGATGTGCGCATCCAAGGCCTCTACTTCACAGAGACTCAAAGGCTCAC
CCTGAGCGAGGTGGGGCTAGAGGAAGCCTCTGACACAGGAAGTGGGCGCATAGCACTTGCTGTGGAAATCTGTGCCTGCCCCCCTGCCTA
CGCTGGTGACTCTTGTCAGGGTTGTAGCCCTGGATACTATCGGGATCATAAAGGCTTGTATACCGGACGGTGTGTTCCCTGCAATTGCAA
CGGACATTCAAATCAATGCCAGGATGGCTCAGGCATATGTGTTAACTGTCAGCACAACACCGCGGGAGAGCACTGTGAACGCTGCCAGGA
GGGCTACTATGGCAACGCCGTCCACGGATCCTGCAGGGCCTGCCCATGTCCTCACACTAACAGCTTTGCCACTGGCTGTGTGGTGAATGG
GGGAGACGTGCGGTGCTCCTGCAAAGCTGGGTACACAGGAACACAGTGTGAAAGGTGTGCACCGGGATATTTCGGGAATCCCCAGAAATT
CGGAGGTAGCTGCCAACCATGCAGTTGTAACAGCAATGGCCAGCTGGGCAGCTGTCATCCCCTGACTGGAGACTGCATAAACCAAGAACC
CAAAGATAGCAGCCCTGCAGAAGAATGTGATGATTGCGACAGCTGTGTGATGACCCTCCTGAACGACCTGGCCACCATGGGCGAGCAGCT
CCGCCTGGTCAAGTCTCAGCTGCAGGGCCTGAGTGCCAGCGCAGGGCTTCTGGAGCAGATGAGGCACATGGAGACCCAGGCCAAGGACCT
GAGGAATCAGTTGCTCAACTACCGTTCTGCCATTTCAAATCATGGATCAAAAATAGAAGGCCTGGAAAGAGAACTGACTGATTTGAATCA
AGAATTTGAGACTTTGCAAGAAAAGGCTCAAGTAAATTCCAGAAAAGCACAAACATTAAACAACAATGTTAATCGGGCAACACAAAGCGC
AAAAGAACTGGATGTGAAGATTAAAAATGTCATCCGGAATGTGCACATTCTTTTAAAGCAGATCTCTGGGACAGATGGAGAGGGAAACAA
CGTGCCTTCAGGTGACTTTTCCAGAGAGTGGGCTGAAGCCCAGCGCATGATGAGGGAACTGCGGAACAGGAACTTTGGAAAGCACCTCAG
AGAAGCAGAAGCTGATAAAAGGGAGTCGCAGCTCTTGCTGAACCGGATAAGGACCTGGCAGAAAACCCACCAGGGGGAGAACAATGGGCT
TGCTAACAGTATCCGGGATTCTTTAAATGAATACGAAGCCAAACTCAGTGACCTTCGTGCTCGGCTGCAGGAGGCAGCTGCCCAAGCCAA
GCAGGCAAATGGCTTGAACCAAGAAAACGAGAGAGCTTTGGGAGCCATTCAGAGACAAGTGAAAGAAATAAATTCCCTGCAGAGTGATTT
CACCAAGTATCTAACCACTGCAGACTCATCTTTGTTGCAAACCAACATTGCGCTGCAGCTGATGGAGAAAAGCCAGAAGGAATATGAAAA
ATTAGCTGCCAGTTTAAATGAAGCAAGACAAGAACTAAGTGACAAAGTAAGAGAACTTTCCAGATCTGCTGGCAAAACATCCCTTGTGGA
GGAGGCAGAAAAGCACGCGCGGTCCTTACAAGAGCTGGCAAAGCAGCTGGAAGAGATCAAGAGAAACGCCAGCGGGGATGAGCTGGTGCG
CTGTGCTGTGGATGCCGCCACCGCCTACGAGAACATCCTCAATGCCATCAAAGCGGCCGAGGACGCAGCCAACAGGGCTGCCAGTGCATC
TGAATCTGCCCTCCAGACAGTGATAAAGGAAGATCTGCCAAGAAAAGCTAAAACCCTGAGTTCCAACAGTGATAAACTGTTAAATGAAGC
CAAGATGACACAAAAGAAGCTAAAGCAAGAAGTCAGTCCAGCTCTCAACAACCTACAGCAAACCCTGAATATTGTGACAGTTCAGAAAGA
AGTGATAGACACCAATCTCACAACTCTCCGAGATGGTCTTCATGGGATACAGAGAGGTGATATTGATGCTATGATCAGTAGTGCAAAGAG
CATGGTCAGAAAGGCCAACGACATCACAGATGAGGTTCTGGATGGGCTCAACCCCATCCAGACAGATGTGGAAAGAATTAAGGACACCTA
TGGGAGGACACAGAACGAAGACTTCAAAAAGGCTCTGACTGATGCAGATAACTCGGTGAATAAGTTAACCAACAAACTACCTGATCTTTG
GCGCAAGATTGAAAGTATCAACCAACAGCTGTTGCCCTTGGGAAACATCTCTGACAACATGGACAGAATACGAGAACTAATTCAGCAGGC
CAGAGATGCTGCCAGTAAGGTTGCTGTCCCCATGAGGTTCAATGGTAAATCTGGAGTCGAAGTCCGACTGCCAAATGACCTGGAAGATTT
GAAAGGATATACATCTCTGTCCTTGTTTCTCCAAAGGCCCAACTCAAGAGAAAATGGGGGTACTGAGAATATGTTTGTGATGTACCTTGG
AAATAAAGATGCCTCCCGGGACTACATCGGCATGGCAGTTGTGGATGGCCAGCTCACCTGTGTCTACAACCTGGGGGACCGTGAGGCTGA
ACTCCAAGTGGACCAGATCTTGACCAAGAGTGAGACTAAGGAGGCAGTTATGGATCGGGTGAAATTTCAGAGAATTTATCAGTTTGCAAG
GCTTAATTACACCAAAGGAGCCACATCCAGTAAACCAGAAACACCCGGAGTCTATGACATGGATGGTAGAAATAGCAATACACTCCTTAA
TTTGGATCCTGAAAATGTTGTATTTTATGTTGGAGGTTACCCACCTGATTTTAAACTTCCCAGTCGACTAAGTTTCCCTCCATACAAAGG
TTGTATTGAATTAGATGACCTCAATGAAAATGTTCTGAGCTTGTACAACTTCAAAAAAACATTCAATCTCAACACAACTGAAGTGGAGCC
TTGTAGAAGGAGGAAGGAAGAGTCAGACAAAAATTATTTTGAAGGTACGGGCTATGCTCGAGTTCCAACTCAACCACATGCTCCCATCCC
AACCTTTGGACAGACAATTCAGACCACCGTGGATAGAGGCTTGCTGTTCTTTGCAGAAAACGGGGATCGCTTCATATCTCTAAATATAGA
AGATGGCAAGCTCATGGTGAGATACAAACTGAATTCAGAGCTACCAAAAGAGAGAGGAGTTGGAGACGCCATAAACAACGGCAGAGACCA
TTCGATTCAGATCAAAATTGGAAAACTCCAAAAGCGTATGTGGATAAATGTGGACGTTCAAAACACTATAATTGATGGTGAAGTATTTGA
TTTCAGCACATATTATCTGGGAGGAATTCCAATTGCAATCAGGGAAAGATTTAACATTTCTACGCCTGCTTTCCGAGGCTGCATGAAAAA
TTTGAAGAAAACCAGTGGTGTCGTTAGATTGAATGATACTGTGGGAGTAACCAAAAAGTGCTCGGAAGACTGGAAGCTTGTGCGATCTGC
CTCATTCTCCAGAGGAGGACAATTGAGTTTCACTGATTTGGGCTTACCACCTACTGACCACCTCCAGGCCTCATTTGGATTTCAGACCTT
TCAACCCAGTGGCATATTATTAGATCATCAGACATGGACAAGGAACCTGCAGGTCACTCTGGAAGATGGTTACATTGAATTGAGCACCAG
CGATAGCGGCAGCCCAATTTTTAAATCTCCACAGACGTATATGGATGGTTTACTGCATTATGTATCTGTAATAAGCGACAACTCTGGACT
ACGGCTTCTCATCGATGACCAGCTTCTGAGAAATAGCAAAAGGCTAAAACACATTTCAAGTTCCCGGCAGTCTCTGCGTCTGGGCGGGAG
CAATTTTGAGGGTTGTATTAGCAATGTTTTTGTCCAGAGGTTATCACTGAGTCCTGAAGTCCTAGATTTGACCAGTAACTCTCTCAAGAG
AGATGTGTCCCTGGGAGGCTGCAGTTTAAACAAACCACCTTTTCTAATGTTGCTTAAAGGTTCTACCAGGTTTAACAAGACCAAGACTTT
TCGTATCAACCAGGACTGGCTGGAAGCAATAGAAGAACATTCTGCTTACAGCACTCACTACTGTTCCCAGGACCAGCTGACTGATGAGGA
GGAGGAAGATACGGTTTCTGCTGCAGACCTGAAGAAATCATTAGAGAAAGCACAGTCATGCCAACAGCGACTAGATAGGGAAATTTCCAA
CTTTCTCAAAATGATTAAGGAGTGTGACATGGCTAAAGAAATGCTTCCATCATTTCTTCAGAAAGTTGAAGTTGTCTCAGAAGCTTCTAG
AGAAACTTGTGTAGCTTTGACTGATTGCCTTAATCTCTTCACCAAACAAGAAGGGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAA
AAACAAAATCTTGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAG
CATCCTTAGCGAGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTC
CTTTGAAGAGGAAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGG
CATCAAGAAACACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAAT
GGAACTATCCAAGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCT
CATCCACAAGGCCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGA
ACGGACTGGAAAACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGT
CAGCCATCACCCACCAATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATT
CTGGGGGAAGAGTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCAC
CTGCTGTGTGCATAATATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATG
TGTGTTGAATTTTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTG
TGCCCTCTATGGGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGA
AGAGAAGAAGAACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGG
AAGCGTTCTTCTATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGT
AGACAAAGACATGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGC
TAGTGAAGAAAAAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTT
CCATCAAGGTCCTAATCCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACAT
TTATTAAAATGCATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTAC
TTATCTTTTAAAAAAAAAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGA
AAGTCTTAGGAAAAATGCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAAT
ATGCTTTTTATGGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAAT
CAAGTTATTTTGAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTT
TATTCTCAGATATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTT
CCATCTTCCAAGAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTT
CATTTACTTAGTGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGT
ATAAAATCTAGCAATTCACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTC
CAGTGGCAAATGCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAA
GTACCTGTGTACTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTA
TTTATCCACCCAAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAAC

>43877_43877_2_LAMA3-OSBPL1A_LAMA3_chr18_21513899_ENST00000313654_OSBPL1A_chr18_21892070_ENST00000319481_length(amino acids)=3581AA_BP=2953
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST
YSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLG
HLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG
HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFH
GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA
LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSE
CKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENN
YYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVILRYVNPGTEAVSGHITIYPSWG
AAQSKEIIFLPSKEPAFVTVPGNGFADPFSITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVT
RFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVEYSTEAAQLFVVDVNVKSSGSVLAGQVNIY
SCNYSVLCRSAVIDHMSRIAMYELLADADIQLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALI
LDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHASFCPHVLGCRD
QVIAEGQIEFDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYH
KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM
AGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE
GSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVS
SYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQG
LYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNT
AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHP
LTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEG
LERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHILLKQISGTDGEGNNVPSGDFSREWAEAQRMMREL
RNRNFGKHLREAEADKRESQLLLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQV
KEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIK
RNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQ
TLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVN
KLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGG
TENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDM
DGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYAR
VPTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQ
NTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDH
LQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISS
SRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLMLLKGSTRFNKTKTFRINQDWLEAIEEHSAYSTHY
CSQDQLTDEEEEDTVSAADLKKSLEKAQSCQQRLDREISNFLKMIKECDMAKEMLPSFLQKVEVVSEASRETCVALTDCLNLFTKQEGVR
NFKLEQEQEKNKILSEALETLATEHHELEQSLVKGSPPASILSEDEFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKD
CGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAF
AVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEH
NEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDA
YKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIR

--------------------------------------------------------------
>43877_43877_3_LAMA3-OSBPL1A_LAMA3_chr18_21513899_ENST00000399516_OSBPL1A_chr18_21892070_ENST00000319481_length(transcript)=11713nt_BP=8694nt
ATGGCGGCGGCCGCGCGGCCTCGGGGTCGGGCACTGGGGCCAGTACTGCCGCCGACGCCGCTGCTCCTGCTGGTACTGCGGGTGCTGCCA
GCCTGCGGGGCGACCGCTCGGGATCCCGGGGCCGCGGCCGGGCTCAGCCTTCACCCGACTTACTTCAACCTGGCCGAGGCGGCGAGGATT
TGGGCCACCGCCACCTGCGGGGAGAGGGGACCCGGCGAGGGGAGGCCCCAGCCCGAGCTCTACTGCAAGTTGGTCGGGGGCCCCACCGCC
CCAGGCAGCGGCCACACCATCCAGGGCCAGTTCTGTGACTATTGCAATTCTGAAGACCCCAGGAAAGCACATCCTGTCACCAATGCCATC
GATGGATCTGAACGTTGGTGGCAAAGCCCTCCCCTGTCCTCAGGCACACAGTACAACAGAGTCAACCTCACCTTGGATCTGGGGCAGCTC
TTCCATGTGGCCTATATTTTAATCAAATTTGCAAATTCTCCTCGCCCTGATCTTTGGGTCTTGGAAAGATCTGTAGACTTTGGAAGCACC
TACTCACCATGGCAATATTTTGCTCATTCTAAAGTAGACTGTTTAAAAGAATTTGGGCGGGAGGCAAATATGGCTGTCACCCGGGATGAT
GATGTACTTTGTGTTACTGAATATTCCCGTATTGTACCTTTGGAAAATGGTGAGGTTGTGGTGTCCTTGATAAACGGTCGTCCAGGTGCA
AAAAATTTTACTTTCTCTCACACCCTGAGGGAGTTTACCAAGGCAACAAACATCCGCTTGCGTTTTCTTAGAACCAATACGCTTCTTGGA
CACCTCATCTCCAAAGCCCAGCGAGATCCAACTGTCACTCGGCGGTATTATTACAGCATAAAGGACATCAGCATTGGTGGGCAGTGTGTT
TGCAATGGCCATGCTGAAGTGTGCAATATAAACAATCCTGAAAAACTGTTTCGGTGTGAATGCCAGCACCACACCTGTGGGGAGACGTGT
GATCGCTGCTGCACAGGGTACAATCAGAGGCGCTGGCGGCCCGCCGCTTGGGAGCAGAGCCACGAGTGTGAAGCATGCAACTGCCACGGC
CATGCCAGCAACTGTTACTATGATCCAGATGTTGAGCGGCAGCAGGCAAGCTTGAATACCCAGGGCATCTATGCTGGTGGAGGGGTCTGC
ATTAACTGTCAGCACAACACAGCTGGAGTAAACTGTGAACAGTGTGCTAAGGGCTATTACCGCCCTTATGGGGTTCCAGTGGATGCCCCT
GATGGCTGCATCCCCTGCAGCTGTGACCCTGAGCATGCGGATGGCTGTGAACAGGGTTCAGGCCGCTGTCACTGCAAGCCAAATTTCCAC
GGAGACAACTGTGAGAAGTGTGCAATTGGATACTACAATTTCCCATTTTGCTTGAGAATTCCCATTTTTCCTGTTTCTACACCAAGTTCA
GAAGATCCAGTAGCTGGAGATATAAAAGGGTGTGACTGTAATCTGGAAGGTGTTCTCCCTGAAATATGTGATGCCCACGGACGGTGCCTG
TGCCGCCCTGGGGTTGAGGGCCCTCGATGTGATACCTGCCGCTCTGGTTTCTACTCATTCCCTATTTGCCAAGCCTGCTGGTGTTCAGCC
CTTGGATCCTACCAGATGCCCTGCAGCTCAGTGACTGGACAGTGTGAATGTCGGCCAGGAGTTACAGGACAGCGGTGTGACAGGTGTCTC
TCAGGAGCTTATGATTTCCCCCACTGCCAAGGTTCCAGCAGTGCTTGTGACCCAGCTGGTACCATCAACTCCAATTTGGGGTATTGCCAA
TGCAAGCTTCATGTTGAAGGTCCTACTTGTAGCCGCTGCAAACTGTTATATTGGAATCTGGACAAAGAAAACCCCAGTGGATGTTCAGAA
TGCAAGTGCCATAAGGCGGGAACAGTGAGTGGAACTGGAGAGTGTAGGCAGGGAGATGGTGACTGTCACTGCAAGTCCCATGTGGGTGGC
GATTCCTGCGACACCTGTGAAGATGGATATTTTGCTTTGGAAAAGAGCAATTACTTTGGGTGTCAAGGGTGTCAGTGTGACATTGGTGGG
GCATTGTCCTCCATGTGCAGTGGGCCCTCGGGAGTGTGCCAGTGCCGAGAGCATGTCGTGGGAAAGGTGTGCCAGCGGCCTGAAAACAAC
TACTATTTCCCAGATTTGCATCATATGAAGTATGAGATTGAAGACGGCAGCACACCTAATGGGAGAGACCTTCGATTTGGATTTGATCCG
CTGGCATTTCCTGAGTTTAGCTGGAGAGGATATGCCCAAATGACCTCAGTACAGAATGATGTAAGAATAACATTGAATGTAGGGAAGTCA
AGTGGCTCCTTGTTTCGTGTTATTCTGAGATACGTTAACCCTGGAACTGAAGCAGTATCTGGCCATATAACTATTTATCCATCCTGGGGT
GCTGCTCAAAGCAAAGAGATCATCTTCCTGCCGAGTAAGGAGCCAGCCTTTGTCACTGTCCCTGGAAATGGTTTTGCAGACCCATTTTCA
ATCACACCAGGAATATGGGTTGCTTGTATTAAGGCAGAAGGAGTCCTTCTGGATTACCTGGTGCTGCTCCCCAGGGACTACTATGAAGCC
TCTGTACTGCAGCTGCCAGTCACAGAACCATGTGCCTACGCAGGACCTCCCCAAGAAAATTGCTTACTCTACCAGCATTTGCCAGTGACC
AGATTCCCCTGTACCCTGGCTTGTGAGGCCAGACACTTCCTGCTTGATGGGGAGCCAAGACCCGTGGCAGTGAGGCAGCCCACACCTGCA
CACCCTGTCATGGTGGACCTCAGCGGGAGAGAGGTGGAATTGCATCTGCGGCTGCGCATCCCACAGGTTGGCCACTACGTGGTTGTGGTC
GAGTATTCCACGGAGGCAGCTCAGCTGTTTGTGGTTGATGTGAATGTGAAGAGCTCCGGGTCTGTTCTGGCAGGCCAGGTGAACATTTAC
AGCTGCAACTACAGTGTTCTCTGCCGGAGTGCTGTGATTGATCACATGAGCCGCATCGCCATGTATGAGCTATTGGCAGATGCAGACATT
CAGCTCAAGGGACACATGGCCCGATTCCTTCTGCATCAAGTTTGTATCATACCTATTGAAGAATTCTCAGCTGAGTATGTGAGACCACAA
GTCCACTGCATTGCCAGTTATGGGCGATTTGTCAATCAAAGTGCCACCTGTGTCTCCTTGGCCCATGAAACTCCTCCAACAGCATTAATT
TTGGATGTTCTAAGTGGCAGGCCTTTCCCTCACCTGCCCCAGCAGTCGTCACCTTCTGTTGATGTTCTTCCTGGGGTCACCTTGAAGGCA
CCGCAGAATCAAGTGACCCTGAGAGGACGTGTACCACACCTGGGCCGATACGTCTTTGTCATCCATTTTTACCAAGCAGCGCACCCGACG
TTTCCCGCGCAGGTGTCGGTGGATGGCGGGTGGCCACGGGCAGGCTCCTTCCATGCCTCTTTTTGCCCCCATGTGCTTGGCTGCCGGGAT
CAAGTGATTGCCGAAGGCCAGATTGAGTTTGACATCTCAGAGCCTGAAGTGGCCGCAACTGTGAAGGTTCCAGAAGGAAAGTCCTTGGTT
TTGGTCCGTGTTCTAGTGGTGCCTGCAGAAAACTATGACTACCAAATACTTCACAAAAAATCCATGGACAAGTCACTCGAGTTTATCACC
AATTGTGGAAAAAACAGCTTTTACCTTGACCCCCAGACAGCCTCCAGATTCTGTAAGAATTCCGCCAGGTCCCTGGTGGCCTTTTACCAC
AAGGGCGCCCTGCCTTGTGAGTGCCACCCCACTGGGGCCACCGGCCCTCACTGCAGCCCTGAGGGTGGGCAGTGCCCATGCCAGCCCAAC
GTCATCGGGCGGCAGTGCACCCGCTGTGCAACAGGCCACTACGGATTCCCACGCTGCAAGCCGTGCAGCTGTGGTCGGCGCCTTTGTGAA
GAGATGACGGGGCAGTGCCGCTGCCCTCCCCGCACGGTCAGGCCCCAGTGTGAGGTGTGTGAGACACACTCATTCAGCTTCCACCCCATG
GCCGGCTGCGAAGGCTGCAACTGTTCCAGGAGGGGCACCATCGAGGCTGCCATGCCGGAGTGTGACCGGGACAGCGGGCAGTGCAGATGC
AAGCCCAGAATCACAGGGCGGCAGTGTGACCGATGTGCTTCCGGGTTTTACCGCTTTCCTGAGTGTGTTCCCTGCAATTGCAACAGAGAT
GGGACTGAGCCAGGAGTGTGTGACCCAGGGACCGGGGCTTGCCTCTGCAAGGAAAATGTAGAAGGCACAGAGTGTAATGTGTGTCGAGAA
GGCTCATTCCATTTGGACCCAGCCAATCTCAAGGGTTGTACCAGCTGTTTCTGTTTTGGAGTAAATAATCAATGTCACAGCTCACATAAG
CGAAGGACTAAGTTTGTGGATATGCTGGGCTGGCACCTGGAGACAGCAGACAGAGTGGACATCCCTGTCTCTTTCAACCCAGGCAGCAAC
AGTATGGTGGCGGATCTCCAGGAGCTGCCCGCAACCATCCACAGCGCGTCCTGGGTCGCACCCACCTCCTACCTGGGGGACAAGGTTTCT
TCATATGGTGGTTACCTCACTTACCAAGCCAAGTCCTTTGGCTTGCCTGGCGACATGGTTCTTCTGGAAAAGAAGCCGGATGTACAGCTC
ACTGGTCAGCACATGTCCATCATCTATGAGGAGACAAACACCCCACGGCCAGACCGGCTGCATCATGGACGAGTGCACGTGGTCGAGGGA
AACTTCAGACATGCCAGCAGCCGTGCCCCAGTGTCTAGGGAGGAGCTGATGACAGTGCTGTCTAGACTGGCAGATGTGCGCATCCAAGGC
CTCTACTTCACAGAGACTCAAAGGCTCACCCTGAGCGAGGTGGGGCTAGAGGAAGCCTCTGACACAGGAAGTGGGCGCATAGCACTTGCT
GTGGAAATCTGTGCCTGCCCCCCTGCCTACGCTGGTGACTCTTGTCAGGGTTGTAGCCCTGGATACTATCGGGATCATAAAGGCTTGTAT
ACCGGACGGTGTGTTCCCTGCAATTGCAACGGACATTCAAATCAATGCCAGGATGGCTCAGGCATATGTGTTAACTGTCAGCACAACACC
GCGGGAGAGCACTGTGAACGCTGCCAGGAGGGCTACTATGGCAACGCCGTCCACGGATCCTGCAGGGCCTGCCCATGTCCTCACACTAAC
AGCTTTGCCACTGGCTGTGTGGTGAATGGGGGAGACGTGCGGTGCTCCTGCAAAGCTGGGTACACAGGAACACAGTGTGAAAGGTGTGCA
CCGGGATATTTCGGGAATCCCCAGAAATTCGGAGGTAGCTGCCAACCATGCAGTTGTAACAGCAATGGCCAGCTGGGCAGCTGTCATCCC
CTGACTGGAGACTGCATAAACCAAGAACCCAAAGATAGCAGCCCTGCAGAAGAATGTGATGATTGCGACAGCTGTGTGATGACCCTCCTG
AACGACCTGGCCACCATGGGCGAGCAGCTCCGCCTGGTCAAGTCTCAGCTGCAGGGCCTGAGTGCCAGCGCAGGGCTTCTGGAGCAGATG
AGGCACATGGAGACCCAGGCCAAGGACCTGAGGAATCAGTTGCTCAACTACCGTTCTGCCATTTCAAATCATGGATCAAAAATAGAAGGC
CTGGAAAGAGAACTGACTGATTTGAATCAAGAATTTGAGACTTTGCAAGAAAAGGCTCAAGTAAATTCCAGAAAAGCACAAACATTAAAC
AACAATGTTAATCGGGCAACACAAAGCGCAAAAGAACTGGATGTGAAGATTAAAAATGTCATCCGGAATGTGCACATGCTGAACCGGATA
AGGACCTGGCAGAAAACCCACCAGGGGGAGAACAATGGGCTTGCTAACAGTATCCGGGATTCTTTAAATGAATACGAAGCCAAACTCAGT
GACCTTCGTGCTCGGCTGCAGGAGGCAGCTGCCCAAGCCAAGCAGGCAAATGGCTTGAACCAAGAAAACGAGAGAGCTTTGGGAGCCATT
CAGAGACAAGTGAAAGAAATAAATTCCCTGCAGAGTGATTTCACCAAGTATCTAACCACTGCAGACTCATCTTTGTTGCAAACCAACATT
GCGCTGCAGCTGATGGAGAAAAGCCAGAAGGAATATGAAAAATTAGCTGCCAGTTTAAATGAAGCAAGACAAGAACTAAGTGACAAAGTA
AGAGAACTTTCCAGATCTGCTGGCAAAACATCCCTTGTGGAGGAGGCAGAAAAGCACGCGCGGTCCTTACAAGAGCTGGCAAAGCAGCTG
GAAGAGATCAAGAGAAACGCCAGCGGGGATGAGCTGGTGCGCTGTGCTGTGGATGCCGCCACCGCCTACGAGAACATCCTCAATGCCATC
AAAGCGGCCGAGGACGCAGCCAACAGGGCTGCCAGTGCATCTGAATCTGCCCTCCAGACAGTGATAAAGGAAGATCTGCCAAGAAAAGCT
AAAACCCTGAGTTCCAACAGTGATAAACTGTTAAATGAAGCCAAGATGACACAAAAGAAGCTAAAGCAAGAAGTCAGTCCAGCTCTCAAC
AACCTACAGCAAACCCTGAATATTGTGACAGTTCAGAAAGAAGTGATAGACACCAATCTCACAACTCTCCGAGATGGTCTTCATGGGATA
CAGAGAGGTGATATTGATGCTATGATCAGTAGTGCAAAGAGCATGGTCAGAAAGGCCAACGACATCACAGATGAGGTTCTGGATGGGCTC
AACCCCATCCAGACAGATGTGGAAAGAATTAAGGACACCTATGGGAGGACACAGAACGAAGACTTCAAAAAGGCTCTGACTGATGCAGAT
AACTCGGTGAATAAGTTAACCAACAAACTACCTGATCTTTGGCGCAAGATTGAAAGTATCAACCAACAGCTGTTGCCCTTGGGAAACATC
TCTGACAACATGGACAGAATACGAGAACTAATTCAGCAGGCCAGAGATGCTGCCAGTAAGGTTGCTGTCCCCATGAGGTTCAATGGTAAA
TCTGGAGTCGAAGTCCGACTGCCAAATGACCTGGAAGATTTGAAAGGATATACATCTCTGTCCTTGTTTCTCCAAAGGCCCAACTCAAGA
GAAAATGGGGGTACTGAGAATATGTTTGTGATGTACCTTGGAAATAAAGATGCCTCCCGGGACTACATCGGCATGGCAGTTGTGGATGGC
CAGCTCACCTGTGTCTACAACCTGGGGGACCGTGAGGCTGAACTCCAAGTGGACCAGATCTTGACCAAGAGTGAGACTAAGGAGGCAGTT
ATGGATCGGGTGAAATTTCAGAGAATTTATCAGTTTGCAAGGCTTAATTACACCAAAGGAGCCACATCCAGTAAACCAGAAACACCCGGA
GTCTATGACATGGATGGTAGAAATAGCAATACACTCCTTAATTTGGATCCTGAAAATGTTGTATTTTATGTTGGAGGTTACCCACCTGAT
TTTAAACTTCCCAGTCGACTAAGTTTCCCTCCATACAAAGGTTGTATTGAATTAGATGACCTCAATGAAAATGTTCTGAGCTTGTACAAC
TTCAAAAAAACATTCAATCTCAACACAACTGAAGTGGAGCCTTGTAGAAGGAGGAAGGAAGAGTCAGACAAAAATTATTTTGAAGGTACG
GGCTATGCTCGAGTTCCAACTCAACCACATGCTCCCATCCCAACCTTTGGACAGACAATTCAGACCACCGTGGATAGAGGCTTGCTGTTC
TTTGCAGAAAACGGGGATCGCTTCATATCTCTAAATATAGAAGATGGCAAGCTCATGGTGAGATACAAACTGAATTCAGAGCTACCAAAA
GAGAGAGGAGTTGGAGACGCCATAAACAACGGCAGAGACCATTCGATTCAGATCAAAATTGGAAAACTCCAAAAGCGTATGTGGATAAAT
GTGGACGTTCAAAACACTATAATTGATGGTGAAGTATTTGATTTCAGCACATATTATCTGGGAGGAATTCCAATTGCAATCAGGGAAAGA
TTTAACATTTCTACGCCTGCTTTCCGAGGCTGCATGAAAAATTTGAAGAAAACCAGTGGTGTCGTTAGATTGAATGATACTGTGGGAGTA
ACCAAAAAGTGCTCGGAAGACTGGAAGCTTGTGCGATCTGCCTCATTCTCCAGAGGAGGACAATTGAGTTTCACTGATTTGGGCTTACCA
CCTACTGACCACCTCCAGGCCTCATTTGGATTTCAGACCTTTCAACCCAGTGGCATATTATTAGATCATCAGACATGGACAAGGAACCTG
CAGGTCACTCTGGAAGATGGTTACATTGAATTGAGCACCAGCGATAGCGGCAGCCCAATTTTTAAATCTCCACAGACGTATATGGATGGT
TTACTGCATTATGTATCTGTAATAAGCGACAACTCTGGACTACGGCTTCTCATCGATGACCAGCTTCTGAGAAATAGCAAAAGGCTAAAA
CACATTTCAAGTTCCCGGCAGTCTCTGCGTCTGGGCGGGAGCAATTTTGAGGGTTGTATTAGCAATGTTTTTGTCCAGAGGTTATCACTG
AGTCCTGAAGTCCTAGATTTGACCAGTAACTCTCTCAAGAGAGATGTGTCCCTGGGAGGCTGCAGTTTAAACAAACCACCTTTTCTAATG
TTGCTTAAAGGTTCTACCAGGTTTAACAAGACCAAGACTTTTCGTATCAACCAGGACTGGCTGGAAGCAATAGAAGAACATTCTGCTTAC
AGCACTCACTACTGTTCCCAGGACCAGCTGACTGATGAGGAGGAGGAAGATACGGTTTCTGCTGCAGACCTGAAGAAATCATTAGAGAAA
GCACAGTCATGCCAACAGCGACTAGATAGGGAAATTTCCAACTTTCTCAAAATGATTAAGGAGTGTGACATGGCTAAAGAAATGCTTCCA
TCATTTCTTCAGAAAGTTGAAGTTGTCTCAGAAGCTTCTAGAGAAACTTGTGTAGCTTTGACTGATTGCCTTAATCTCTTCACCAAACAA
GAAGGGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAAAACAAAATCTTGTCAGAAGCACTGGAGACGCTGGCCACTGAACATCAT
GAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGCATCCTTAGCGAGGACGAGTTCTATGATGCGCTGTCAGATTCCGAGTCC
GAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCCTTTGAAGAGGAAGGAGAGCATTTGGGCAGTAGAAAACACAGAATGTCC
GAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGCATCAAGAAACACAGAACAAGTTTGCCTTCTCCTATGTTTTCCAGAAAT
GACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATGGAACTATCCAAGATCACGATGCCAGTTATATTTAATGAGCCTCTGAGC
TTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTCATCCACAAGGCCAGTTCACTCTCTGATCCTGTGGAAAGGATGCAGTGT
GTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAACGGACTGGAAAACCTTTCAACCCACTGCTGGGAGAGACTTATGAATTA
GTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTCAGCCATCACCCACCAATCAGTGCATTTCATGCTGAAGGATTAAACAAT
GACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTCTGGGGGAAGAGTGTAGAAGCAGAACCCAAAGGAACCATCACCTTGGAG
CTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACCTGCTGTGTGCATAATATCATTGTGGGTAAACTGTGGATCGAACAGTAT
GGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGTGTGTTGAATTTTAAGCCATGTGGCCTTTTTGGTAAGGAATTACACAAA
GTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGTGCCCTCTATGGGAAGTGGACTGAATGTTTATACAGTGTTGACCCTGCC
ACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAAGAGAAGAAGAACAGCAAACAGATGAGCACCTCTGAGGAGTTGGATGAA
ATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGAAGCGTTCTTCTATGGCGAATAGCCCCACGGCCTCCAAATTCTGCCCAG
ATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTAGACAAAGACATGGAGAGTGTGATTCCCAAGACAGACTGCAGGTTACGG
CCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCTAGTGAAGAAAAAAAACGACTTGAGGAAAAACAAAGAGCAGCCCGCAAA
AACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTCCATCAAGGTCCTAATCCCTACAATGGAGCACAGGACTGGATTTACTCT
GGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATTTATTAAAATGCATACAAGTCAGGGTGTTTGGCTAATCTACAAATAAGT
CTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACTTATCTTTTAAAAAAAAAAATGAAAAAACACTCATGAGATAACTGCATT
TCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAAAGTCTTAGGAAAAATGCATAATTTTGCTATAAAATGTACTTATTTGGA
ATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATATGCTTTTTATGGTTGCTGTTGCCATATTTACTGAAGGTTTATACCTAA
ATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATCAAGTTATTTTGAATATTTTTATGCTGTCATGCTTGAATGTTTTAGATG
TAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTTATTCTCAGATATAGAGGTTATGTCATTTTATAAAGACTTCATTGATAA
GATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTCCATCTTCCAAGAAGAAAAAAAATGCCTGAATATTCAGAATAGATATTT
CTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTCATTTACTTAGTGCTCTGAATTTACTTTTACAGTTTTCTGCAGTCAGTA
TCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTATAAAATCTAGCAATTCACAAAAATGCCCTAGAAATATAGATTTTAATC
ACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCCAGTGGCAAATGCCACTAGGGAAAGTAAGTTGCACTCATGTAAGTATCA
AACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAGTACCTGTGTACTTAAAATATGTGTGGAGACCTACTGTACAGTAGTTTT
GCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTATTTATCCACCCAAACCCCAGACTGAGATACTGCTCCCAGGGGCCTAGGT
AGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACAAGTGTTATAATGAAATAATCTACCTGATGCTAAATAAAGGCTTTAGAA

>43877_43877_3_LAMA3-OSBPL1A_LAMA3_chr18_21513899_ENST00000399516_OSBPL1A_chr18_21892070_ENST00000319481_length(amino acids)=3525AA_BP=2897
MAAAARPRGRALGPVLPPTPLLLLVLRVLPACGATARDPGAAAGLSLHPTYFNLAEAARIWATATCGERGPGEGRPQPELYCKLVGGPTA
PGSGHTIQGQFCDYCNSEDPRKAHPVTNAIDGSERWWQSPPLSSGTQYNRVNLTLDLGQLFHVAYILIKFANSPRPDLWVLERSVDFGST
YSPWQYFAHSKVDCLKEFGREANMAVTRDDDVLCVTEYSRIVPLENGEVVVSLINGRPGAKNFTFSHTLREFTKATNIRLRFLRTNTLLG
HLISKAQRDPTVTRRYYYSIKDISIGGQCVCNGHAEVCNINNPEKLFRCECQHHTCGETCDRCCTGYNQRRWRPAAWEQSHECEACNCHG
HASNCYYDPDVERQQASLNTQGIYAGGGVCINCQHNTAGVNCEQCAKGYYRPYGVPVDAPDGCIPCSCDPEHADGCEQGSGRCHCKPNFH
GDNCEKCAIGYYNFPFCLRIPIFPVSTPSSEDPVAGDIKGCDCNLEGVLPEICDAHGRCLCRPGVEGPRCDTCRSGFYSFPICQACWCSA
LGSYQMPCSSVTGQCECRPGVTGQRCDRCLSGAYDFPHCQGSSSACDPAGTINSNLGYCQCKLHVEGPTCSRCKLLYWNLDKENPSGCSE
CKCHKAGTVSGTGECRQGDGDCHCKSHVGGDSCDTCEDGYFALEKSNYFGCQGCQCDIGGALSSMCSGPSGVCQCREHVVGKVCQRPENN
YYFPDLHHMKYEIEDGSTPNGRDLRFGFDPLAFPEFSWRGYAQMTSVQNDVRITLNVGKSSGSLFRVILRYVNPGTEAVSGHITIYPSWG
AAQSKEIIFLPSKEPAFVTVPGNGFADPFSITPGIWVACIKAEGVLLDYLVLLPRDYYEASVLQLPVTEPCAYAGPPQENCLLYQHLPVT
RFPCTLACEARHFLLDGEPRPVAVRQPTPAHPVMVDLSGREVELHLRLRIPQVGHYVVVVEYSTEAAQLFVVDVNVKSSGSVLAGQVNIY
SCNYSVLCRSAVIDHMSRIAMYELLADADIQLKGHMARFLLHQVCIIPIEEFSAEYVRPQVHCIASYGRFVNQSATCVSLAHETPPTALI
LDVLSGRPFPHLPQQSSPSVDVLPGVTLKAPQNQVTLRGRVPHLGRYVFVIHFYQAAHPTFPAQVSVDGGWPRAGSFHASFCPHVLGCRD
QVIAEGQIEFDISEPEVAATVKVPEGKSLVLVRVLVVPAENYDYQILHKKSMDKSLEFITNCGKNSFYLDPQTASRFCKNSARSLVAFYH
KGALPCECHPTGATGPHCSPEGGQCPCQPNVIGRQCTRCATGHYGFPRCKPCSCGRRLCEEMTGQCRCPPRTVRPQCEVCETHSFSFHPM
AGCEGCNCSRRGTIEAAMPECDRDSGQCRCKPRITGRQCDRCASGFYRFPECVPCNCNRDGTEPGVCDPGTGACLCKENVEGTECNVCRE
GSFHLDPANLKGCTSCFCFGVNNQCHSSHKRRTKFVDMLGWHLETADRVDIPVSFNPGSNSMVADLQELPATIHSASWVAPTSYLGDKVS
SYGGYLTYQAKSFGLPGDMVLLEKKPDVQLTGQHMSIIYEETNTPRPDRLHHGRVHVVEGNFRHASSRAPVSREELMTVLSRLADVRIQG
LYFTETQRLTLSEVGLEEASDTGSGRIALAVEICACPPAYAGDSCQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDGSGICVNCQHNT
AGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSCNSNGQLGSCHP
LTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRSAISNHGSKIEG
LERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSIRDSLNEYEAKLS
DLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASLNEARQELSDKV
RELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQTVIKEDLPRKA
KTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKANDITDEVLDGL
NPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAASKVAVPMRFNGK
SGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQILTKSETKEAV
MDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELDDLNENVLSLYN
FKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLMVRYKLNSELPK
ERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTSGVVRLNDTVGV
TKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGSPIFKSPQTYMDG
LLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLGGCSLNKPPFLM
LLKGSTRFNKTKTFRINQDWLEAIEEHSAYSTHYCSQDQLTDEEEEDTVSAADLKKSLEKAQSCQQRLDREISNFLKMIKECDMAKEMLP
SFLQKVEVVSEASRETCVALTDCLNLFTKQEGVRNFKLEQEQEKNKILSEALETLATEHHELEQSLVKGSPPASILSEDEFYDALSDSES
ERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKITMPVIFNEPLS
FLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPPISAFHAEGLNN
DFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFKPCGLFGKELHK
VEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLWRIAPRPPNSAQ
MYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPNPYNGAQDWIYS

--------------------------------------------------------------
>43877_43877_4_LAMA3-OSBPL1A_LAMA3_chr18_21513899_ENST00000587184_OSBPL1A_chr18_21892070_ENST00000319481_length(transcript)=6886nt_BP=3867nt
ATGCCTCCAGCAGTGAGGCGGTCAGCCTGCAGCATGGGATGGCTGTGGATCTTTGGGGCAGCCCTGGGGCAGTGTCTGGGCTACAGTTCA
CAGCAGCAAAGGGTGCCATTTCTTCAGCCTCCCGGTCAAAGTCAACTGCAAGCGAGTTATGTGGAGTTTAGACCCAGCCAGGGTTGTAGC
CCTGGATACTATCGGGATCATAAAGGCTTGTATACCGGACGGTGTGTTCCCTGCAATTGCAACGGACATTCAAATCAATGCCAGGATGGC
TCAGGCATATGTGTTAACTGTCAGCACAACACCGCGGGAGAGCACTGTGAACGCTGCCAGGAGGGCTACTATGGCAACGCCGTCCACGGA
TCCTGCAGGGCCTGCCCATGTCCTCACACTAACAGCTTTGCCACTGGCTGTGTGGTGAATGGGGGAGACGTGCGGTGCTCCTGCAAAGCT
GGGTACACAGGAACACAGTGTGAAAGGTGTGCACCGGGATATTTCGGGAATCCCCAGAAATTCGGAGGTAGCTGCCAACCATGCAGTTGT
AACAGCAATGGCCAGCTGGGCAGCTGTCATCCCCTGACTGGAGACTGCATAAACCAAGAACCCAAAGATAGCAGCCCTGCAGAAGAATGT
GATGATTGCGACAGCTGTGTGATGACCCTCCTGAACGACCTGGCCACCATGGGCGAGCAGCTCCGCCTGGTCAAGTCTCAGCTGCAGGGC
CTGAGTGCCAGCGCAGGGCTTCTGGAGCAGATGAGGCACATGGAGACCCAGGCCAAGGACCTGAGGAATCAGTTGCTCAACTACCGTTCT
GCCATTTCAAATCATGGATCAAAAATAGAAGGCCTGGAAAGAGAACTGACTGATTTGAATCAAGAATTTGAGACTTTGCAAGAAAAGGCT
CAAGTAAATTCCAGAAAAGCACAAACATTAAACAACAATGTTAATCGGGCAACACAAAGCGCAAAAGAACTGGATGTGAAGATTAAAAAT
GTCATCCGGAATGTGCACATGCTGAACCGGATAAGGACCTGGCAGAAAACCCACCAGGGGGAGAACAATGGGCTTGCTAACAGTATCCGG
GATTCTTTAAATGAATACGAAGCCAAACTCAGTGACCTTCGTGCTCGGCTGCAGGAGGCAGCTGCCCAAGCCAAGCAGGCAAATGGCTTG
AACCAAGAAAACGAGAGAGCTTTGGGAGCCATTCAGAGACAAGTGAAAGAAATAAATTCCCTGCAGAGTGATTTCACCAAGTATCTAACC
ACTGCAGACTCATCTTTGTTGCAAACCAACATTGCGCTGCAGCTGATGGAGAAAAGCCAGAAGGAATATGAAAAATTAGCTGCCAGTTTA
AATGAAGCAAGACAAGAACTAAGTGACAAAGTAAGAGAACTTTCCAGATCTGCTGGCAAAACATCCCTTGTGGAGGAGGCAGAAAAGCAC
GCGCGGTCCTTACAAGAGCTGGCAAAGCAGCTGGAAGAGATCAAGAGAAACGCCAGCGGGGATGAGCTGGTGCGCTGTGCTGTGGATGCC
GCCACCGCCTACGAGAACATCCTCAATGCCATCAAAGCGGCCGAGGACGCAGCCAACAGGGCTGCCAGTGCATCTGAATCTGCCCTCCAG
ACAGTGATAAAGGAAGATCTGCCAAGAAAAGCTAAAACCCTGAGTTCCAACAGTGATAAACTGTTAAATGAAGCCAAGATGACACAAAAG
AAGCTAAAGCAAGAAGTCAGTCCAGCTCTCAACAACCTACAGCAAACCCTGAATATTGTGACAGTTCAGAAAGAAGTGATAGACACCAAT
CTCACAACTCTCCGAGATGGTCTTCATGGGATACAGAGAGGTGATATTGATGCTATGATCAGTAGTGCAAAGAGCATGGTCAGAAAGGCC
AACGACATCACAGATGAGGTTCTGGATGGGCTCAACCCCATCCAGACAGATGTGGAAAGAATTAAGGACACCTATGGGAGGACACAGAAC
GAAGACTTCAAAAAGGCTCTGACTGATGCAGATAACTCGGTGAATAAGTTAACCAACAAACTACCTGATCTTTGGCGCAAGATTGAAAGT
ATCAACCAACAGCTGTTGCCCTTGGGAAACATCTCTGACAACATGGACAGAATACGAGAACTAATTCAGCAGGCCAGAGATGCTGCCAGT
AAGGTTGCTGTCCCCATGAGGTTCAATGGTAAATCTGGAGTCGAAGTCCGACTGCCAAATGACCTGGAAGATTTGAAAGGATATACATCT
CTGTCCTTGTTTCTCCAAAGGCCCAACTCAAGAGAAAATGGGGGTACTGAGAATATGTTTGTGATGTACCTTGGAAATAAAGATGCCTCC
CGGGACTACATCGGCATGGCAGTTGTGGATGGCCAGCTCACCTGTGTCTACAACCTGGGGGACCGTGAGGCTGAACTCCAAGTGGACCAG
ATCTTGACCAAGAGTGAGACTAAGGAGGCAGTTATGGATCGGGTGAAATTTCAGAGAATTTATCAGTTTGCAAGGCTTAATTACACCAAA
GGAGCCACATCCAGTAAACCAGAAACACCCGGAGTCTATGACATGGATGGTAGAAATAGCAATACACTCCTTAATTTGGATCCTGAAAAT
GTTGTATTTTATGTTGGAGGTTACCCACCTGATTTTAAACTTCCCAGTCGACTAAGTTTCCCTCCATACAAAGGTTGTATTGAATTAGAT
GACCTCAATGAAAATGTTCTGAGCTTGTACAACTTCAAAAAAACATTCAATCTCAACACAACTGAAGTGGAGCCTTGTAGAAGGAGGAAG
GAAGAGTCAGACAAAAATTATTTTGAAGGTACGGGCTATGCTCGAGTTCCAACTCAACCACATGCTCCCATCCCAACCTTTGGACAGACA
ATTCAGACCACCGTGGATAGAGGCTTGCTGTTCTTTGCAGAAAACGGGGATCGCTTCATATCTCTAAATATAGAAGATGGCAAGCTCATG
GTGAGATACAAACTGAATTCAGAGCTACCAAAAGAGAGAGGAGTTGGAGACGCCATAAACAACGGCAGAGACCATTCGATTCAGATCAAA
ATTGGAAAACTCCAAAAGCGTATGTGGATAAATGTGGACGTTCAAAACACTATAATTGATGGTGAAGTATTTGATTTCAGCACATATTAT
CTGGGAGGAATTCCAATTGCAATCAGGGAAAGATTTAACATTTCTACGCCTGCTTTCCGAGGCTGCATGAAAAATTTGAAGAAAACCAGT
GGTGTCGTTAGATTGAATGATACTGTGGGAGTAACCAAAAAGTGCTCGGAAGACTGGAAGCTTGTGCGATCTGCCTCATTCTCCAGAGGA
GGACAATTGAGTTTCACTGATTTGGGCTTACCACCTACTGACCACCTCCAGGCCTCATTTGGATTTCAGACCTTTCAACCCAGTGGCATA
TTATTAGATCATCAGACATGGACAAGGAACCTGCAGGTCACTCTGGAAGATGGTTACATTGAATTGAGCACCAGCGATAGCGGCAGCCCA
ATTTTTAAATCTCCACAGACGTATATGGATGGTTTACTGCATTATGTATCTGTAATAAGCGACAACTCTGGACTACGGCTTCTCATCGAT
GACCAGCTTCTGAGAAATAGCAAAAGGCTAAAACACATTTCAAGTTCCCGGCAGTCTCTGCGTCTGGGCGGGAGCAATTTTGAGGGTTGT
ATTAGCAATGTTTTTGTCCAGAGGTTATCACTGAGTCCTGAAGTCCTAGATTTGACCAGTAACTCTCTCAAGAGAGATGTGTCCCTGGGA
GGCTGCAGTTTAAACAAACCACCTTTTCTAATGTTGCTTAAAGGTTCTACCAGGTTTAACAAGACCAAGACTTTTCGTATCAACCAGGAC
TGGCTGGAAGCAATAGAAGAACATTCTGCTTACAGCACTCACTACTGTTCCCAGGACCAGCTGACTGATGAGGAGGAGGAAGATACGGTT
TCTGCTGCAGACCTGAAGAAATCATTAGAGAAAGCACAGTCATGCCAACAGCGACTAGATAGGGAAATTTCCAACTTTCTCAAAATGATT
AAGGAGTGTGACATGGCTAAAGAAATGCTTCCATCATTTCTTCAGAAAGTTGAAGTTGTCTCAGAAGCTTCTAGAGAAACTTGTGTAGCT
TTGACTGATTGCCTTAATCTCTTCACCAAACAAGAAGGGGTGAGGAATTTTAAATTGGAACAAGAGCAAGAAAAAAACAAAATCTTGTCA
GAAGCACTGGAGACGCTGGCCACTGAACATCATGAATTAGAGCAGTCTCTGGTGAAAGGCTCTCCACCCGCCAGCATCCTTAGCGAGGAC
GAGTTCTATGATGCGCTGTCAGATTCCGAGTCCGAAAGGTCCCTGAGTAGATTGGAAGCAGTGACAGCACGCTCCTTTGAAGAGGAAGGA
GAGCATTTGGGCAGTAGAAAACACAGAATGTCCGAAGAAAAAGACTGTGGTGGCGGAGATGCTCTCTCCAATGGCATCAAGAAACACAGA
ACAAGTTTGCCTTCTCCTATGTTTTCCAGAAATGACTTCAGTATCTGGAGCATCCTCAGAAAATGTATTGGAATGGAACTATCCAAGATC
ACGATGCCAGTTATATTTAATGAGCCTCTGAGCTTCCTACAGCGCCTAACTGAATACATGGAGCATACTTACCTCATCCACAAGGCCAGT
TCACTCTCTGATCCTGTGGAAAGGATGCAGTGTGTAGCTGCGTTTGCTGTATCTGCTGTTGCTTCTCAGTGGGAACGGACTGGAAAACCT
TTCAACCCACTGCTGGGAGAGACTTATGAATTAGTGCGAGATGACCTTGGATTTAGACTCATCTCCGAACAGGTCAGCCATCACCCACCA
ATCAGTGCATTTCATGCTGAAGGATTAAACAATGACTTCATCTTTCATGGCTCTATCTATCCCAAACTGAAATTCTGGGGGAAGAGTGTA
GAAGCAGAACCCAAAGGAACCATCACCTTGGAGCTCCTTGAACACAATGAGGCATATACATGGACAAATCCCACCTGCTGTGTGCATAAT
ATCATTGTGGGTAAACTGTGGATCGAACAGTATGGCAATGTGGAAATTATAAACCACAAGACTGGGGACAAATGTGTGTTGAATTTTAAG
CCATGTGGCCTTTTTGGTAAGGAATTACACAAAGTTGAAGGCTACATTCAAGATAAAAGCAAAAAGAAGCTCTGTGCCCTCTATGGGAAG
TGGACTGAATGTTTATACAGTGTTGACCCTGCCACGTTTGACGCTTACAAAAAAAATGATAAGAAAAATACAGAAGAGAAGAAGAACAGC
AAACAGATGAGCACCTCTGAGGAGTTGGATGAAATGCCAGTGCCGGATTCTGAAAGTGTATTCATTATCCCTGGAAGCGTTCTTCTATGG
CGAATAGCCCCACGGCCTCCAAATTCTGCCCAGATGTATAATTTTACTAGTTTTGCAATGGTTTTGAATGAAGTAGACAAAGACATGGAG
AGTGTGATTCCCAAGACAGACTGCAGGTTACGGCCTGACATCAGAGCCATGGAAAATGGAGAGATAGATCAAGCTAGTGAAGAAAAAAAA
CGACTTGAGGAAAAACAAAGAGCAGCCCGCAAAAACAGGTCCAAGTCAGAAGAGGACTGGAAGACGAGGTGGTTCCATCAAGGTCCTAAT
CCCTACAATGGAGCACAGGACTGGATTTACTCTGGCAGCTACTGGGACAGAAATTACTTCAATTTGCCTGACATTTATTAAAATGCATAC
AAGTCAGGGTGTTTGGCTAATCTACAAATAAGTCTTAAACCTATGTTTTTAAATTTTTTTCCCTTGGTTTCTACTTATCTTTTAAAAAAA
AAAATGAAAAAACACTCATGAGATAACTGCATTTCACCCAACAAAAGCAGGGTATAAGGCGATATTGGTGATGAAAGTCTTAGGAAAAAT
GCATAATTTTGCTATAAAATGTACTTATTTGGAATACTATTTTATATAGAGGTAAGAGAACACTGCTGGGGAATATGCTTTTTATGGTTG
CTGTTGCCATATTTACTGAAGGTTTATACCTAAATGTAACTTTAGCTTTATGGAACTATATAGTAATCCCAAATCAAGTTATTTTGAATA
TTTTTATGCTGTCATGCTTGAATGTTTTAGATGTAACCTTTGACATATTTAGAACTCTCCTCCTATACAATGTTTATTCTCAGATATAGA
GGTTATGTCATTTTATAAAGACTTCATTGATAAGATGGCTTTTATTCATACTAATCCTCCCAATGTTACCCCTTCCATCTTCCAAGAAGA
AAAAAAATGCCTGAATATTCAGAATAGATATTTCTGATTTGAAAATTCTAAAGAATTAAACTGGAAAAGTATTTCATTTACTTAGTGCTC
TGAATTTACTTTTACAGTTTTCTGCAGTCAGTATCATTAAAATGGTTAAGTTTACATTTGAACTGAAAATATGTATAAAATCTAGCAATT
CACAAAAATGCCCTAGAAATATAGATTTTAATCACCATTACATAATGACAAACCTTGTTAAATGCTTCCACTTCCAGTGGCAAATGCCAC
TAGGGAAAGTAAGTTGCACTCATGTAAGTATCAAACTATATAAAAGGAGGCCTTGTGCATTTCAAGTTTGCAAAGTACCTGTGTACTTAA
AATATGTGTGGAGACCTACTGTACAGTAGTTTTGCCCCTTTAATTGGGGCACATTCATCTTAAATCTTATAGTATTTATCCACCCAAACC
CCAGACTGAGATACTGCTCCCAGGGGCCTAGGTAGCTGCCAGTCCGTGATTTTAATTGCTGTCTTGAAGTTAACAAGTGTTATAATGAAA

>43877_43877_4_LAMA3-OSBPL1A_LAMA3_chr18_21513899_ENST00000587184_OSBPL1A_chr18_21892070_ENST00000319481_length(amino acids)=1916AA_BP=1288
MPPAVRRSACSMGWLWIFGAALGQCLGYSSQQQRVPFLQPPGQSQLQASYVEFRPSQGCSPGYYRDHKGLYTGRCVPCNCNGHSNQCQDG
SGICVNCQHNTAGEHCERCQEGYYGNAVHGSCRACPCPHTNSFATGCVVNGGDVRCSCKAGYTGTQCERCAPGYFGNPQKFGGSCQPCSC
NSNGQLGSCHPLTGDCINQEPKDSSPAEECDDCDSCVMTLLNDLATMGEQLRLVKSQLQGLSASAGLLEQMRHMETQAKDLRNQLLNYRS
AISNHGSKIEGLERELTDLNQEFETLQEKAQVNSRKAQTLNNNVNRATQSAKELDVKIKNVIRNVHMLNRIRTWQKTHQGENNGLANSIR
DSLNEYEAKLSDLRARLQEAAAQAKQANGLNQENERALGAIQRQVKEINSLQSDFTKYLTTADSSLLQTNIALQLMEKSQKEYEKLAASL
NEARQELSDKVRELSRSAGKTSLVEEAEKHARSLQELAKQLEEIKRNASGDELVRCAVDAATAYENILNAIKAAEDAANRAASASESALQ
TVIKEDLPRKAKTLSSNSDKLLNEAKMTQKKLKQEVSPALNNLQQTLNIVTVQKEVIDTNLTTLRDGLHGIQRGDIDAMISSAKSMVRKA
NDITDEVLDGLNPIQTDVERIKDTYGRTQNEDFKKALTDADNSVNKLTNKLPDLWRKIESINQQLLPLGNISDNMDRIRELIQQARDAAS
KVAVPMRFNGKSGVEVRLPNDLEDLKGYTSLSLFLQRPNSRENGGTENMFVMYLGNKDASRDYIGMAVVDGQLTCVYNLGDREAELQVDQ
ILTKSETKEAVMDRVKFQRIYQFARLNYTKGATSSKPETPGVYDMDGRNSNTLLNLDPENVVFYVGGYPPDFKLPSRLSFPPYKGCIELD
DLNENVLSLYNFKKTFNLNTTEVEPCRRRKEESDKNYFEGTGYARVPTQPHAPIPTFGQTIQTTVDRGLLFFAENGDRFISLNIEDGKLM
VRYKLNSELPKERGVGDAINNGRDHSIQIKIGKLQKRMWINVDVQNTIIDGEVFDFSTYYLGGIPIAIRERFNISTPAFRGCMKNLKKTS
GVVRLNDTVGVTKKCSEDWKLVRSASFSRGGQLSFTDLGLPPTDHLQASFGFQTFQPSGILLDHQTWTRNLQVTLEDGYIELSTSDSGSP
IFKSPQTYMDGLLHYVSVISDNSGLRLLIDDQLLRNSKRLKHISSSRQSLRLGGSNFEGCISNVFVQRLSLSPEVLDLTSNSLKRDVSLG
GCSLNKPPFLMLLKGSTRFNKTKTFRINQDWLEAIEEHSAYSTHYCSQDQLTDEEEEDTVSAADLKKSLEKAQSCQQRLDREISNFLKMI
KECDMAKEMLPSFLQKVEVVSEASRETCVALTDCLNLFTKQEGVRNFKLEQEQEKNKILSEALETLATEHHELEQSLVKGSPPASILSED
EFYDALSDSESERSLSRLEAVTARSFEEEGEHLGSRKHRMSEEKDCGGGDALSNGIKKHRTSLPSPMFSRNDFSIWSILRKCIGMELSKI
TMPVIFNEPLSFLQRLTEYMEHTYLIHKASSLSDPVERMQCVAAFAVSAVASQWERTGKPFNPLLGETYELVRDDLGFRLISEQVSHHPP
ISAFHAEGLNNDFIFHGSIYPKLKFWGKSVEAEPKGTITLELLEHNEAYTWTNPTCCVHNIIVGKLWIEQYGNVEIINHKTGDKCVLNFK
PCGLFGKELHKVEGYIQDKSKKKLCALYGKWTECLYSVDPATFDAYKKNDKKNTEEKKNSKQMSTSEELDEMPVPDSESVFIIPGSVLLW
RIAPRPPNSAQMYNFTSFAMVLNEVDKDMESVIPKTDCRLRPDIRAMENGEIDQASEEKKRLEEKQRAARKNRSKSEEDWKTRWFHQGPN

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Fusion Gene PPI Analysis for LAMA3-OSBPL1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneOSBPL1Achr18:21513899chr18:21892070ENST000003570410161_2370569.0RAB7A
TgeneOSBPL1Achr18:21513899chr18:21892070ENST000003994430141_2370438.0RAB7A


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneOSBPL1Achr18:21513899chr18:21892070ENST0000031948111281_237323.0951.0RAB7A


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LAMA3-OSBPL1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LAMA3-OSBPL1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource