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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:LAMP2-UPF3B (FusionGDB2 ID:44000) |
Fusion Gene Summary for LAMP2-UPF3B |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LAMP2-UPF3B | Fusion gene ID: 44000 | Hgene | Tgene | Gene symbol | LAMP2 | UPF3B | Gene ID | 3920 | 65109 |
| Gene name | lysosomal associated membrane protein 2 | UPF3B regulator of nonsense mediated mRNA decay | |
| Synonyms | CD107b|DND|LAMP-2|LAMPB|LGP-96|LGP110 | HUPF3B|MRX62|MRX82|MRXS14|RENT3B|UPF3BP1|UPF3BP2|UPF3BP3|UPF3X|Upf3p-X | |
| Cytomap | Xq24 | Xq24 | |
| Type of gene | protein-coding | protein-coding | |
| Description | lysosome-associated membrane glycoprotein 2CD107 antigen-like family member B | regulator of nonsense transcripts 3BUPF3 regulator of nonsense transcripts homolog BUPF3B pseudogene 1UPF3B pseudogene 2UPF3B pseudogene 3mental retardation, X-linked 62nonsense mRNA reducing factor 3Bup-frameshift suppressor 3 homolog Bup-framesh | |
| Modification date | 20200321 | 20200313 | |
| UniProtAcc | . | . | |
| Ensembl transtripts involved in fusion gene | ENST00000200639, ENST00000371335, ENST00000434600, ENST00000538785, ENST00000540603, | ENST00000478840, ENST00000276201, ENST00000345865, | |
| Fusion gene scores | * DoF score | 7 X 6 X 5=210 | 2 X 2 X 2=8 |
| # samples | 8 | 2 | |
| ** MAII score | log2(8/210*10)=-1.39231742277876 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: LAMP2 [Title/Abstract] AND UPF3B [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | LAMP2(119602961)-UPF3B(118985836), # samples:1 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Tgene | UPF3B | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | 16601204 |
| Tgene | UPF3B | GO:0045727 | positive regulation of translation | 16601204 |
| Fusion gene breakpoints across LAMP2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across UPF3B (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | COAD | TCGA-A6-6650-01A | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
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Fusion Gene ORF analysis for LAMP2-UPF3B |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000200639 | ENST00000478840 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| 5CDS-intron | ENST00000371335 | ENST00000478840 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| 5CDS-intron | ENST00000434600 | ENST00000478840 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| 5CDS-intron | ENST00000538785 | ENST00000478840 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| In-frame | ENST00000200639 | ENST00000276201 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| In-frame | ENST00000200639 | ENST00000345865 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| In-frame | ENST00000371335 | ENST00000276201 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| In-frame | ENST00000371335 | ENST00000345865 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| In-frame | ENST00000434600 | ENST00000276201 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| In-frame | ENST00000434600 | ENST00000345865 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| In-frame | ENST00000538785 | ENST00000276201 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| In-frame | ENST00000538785 | ENST00000345865 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| intron-3CDS | ENST00000540603 | ENST00000276201 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| intron-3CDS | ENST00000540603 | ENST00000345865 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| intron-intron | ENST00000540603 | ENST00000478840 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000434600 | LAMP2 | chrX | 119602961 | - | ENST00000276201 | UPF3B | chrX | 118985836 | - | 2412 | 260 | 287 | 1555 | 422 |
| ENST00000434600 | LAMP2 | chrX | 119602961 | - | ENST00000345865 | UPF3B | chrX | 118985836 | - | 2369 | 260 | 287 | 1516 | 409 |
| ENST00000538785 | LAMP2 | chrX | 119602961 | - | ENST00000276201 | UPF3B | chrX | 118985836 | - | 2376 | 224 | 251 | 1519 | 422 |
| ENST00000538785 | LAMP2 | chrX | 119602961 | - | ENST00000345865 | UPF3B | chrX | 118985836 | - | 2333 | 224 | 251 | 1480 | 409 |
| ENST00000200639 | LAMP2 | chrX | 119602961 | - | ENST00000276201 | UPF3B | chrX | 118985836 | - | 2353 | 201 | 228 | 1496 | 422 |
| ENST00000200639 | LAMP2 | chrX | 119602961 | - | ENST00000345865 | UPF3B | chrX | 118985836 | - | 2310 | 201 | 228 | 1457 | 409 |
| ENST00000371335 | LAMP2 | chrX | 119602961 | - | ENST00000276201 | UPF3B | chrX | 118985836 | - | 2353 | 201 | 228 | 1496 | 422 |
| ENST00000371335 | LAMP2 | chrX | 119602961 | - | ENST00000345865 | UPF3B | chrX | 118985836 | - | 2310 | 201 | 228 | 1457 | 409 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000434600 | ENST00000276201 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - | 0.000878826 | 0.9991211 |
| ENST00000434600 | ENST00000345865 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - | 0.001018473 | 0.99898154 |
| ENST00000538785 | ENST00000276201 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - | 0.000874837 | 0.9991252 |
| ENST00000538785 | ENST00000345865 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - | 0.001005833 | 0.9989942 |
| ENST00000200639 | ENST00000276201 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - | 0.000873012 | 0.999127 |
| ENST00000200639 | ENST00000345865 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - | 0.000994849 | 0.99900514 |
| ENST00000371335 | ENST00000276201 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - | 0.000873012 | 0.999127 |
| ENST00000371335 | ENST00000345865 | LAMP2 | chrX | 119602961 | - | UPF3B | chrX | 118985836 | - | 0.000994849 | 0.99900514 |
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Fusion Genomic Features for LAMP2-UPF3B |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for LAMP2-UPF3B |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chrX:119602961/chrX:118985836) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| . | . |
| FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Tgene | UPF3B | chrX:119602961 | chrX:118985836 | ENST00000276201 | 0 | 11 | 424_483 | 52 | 484.0 | Region | Sufficient for association with EJC core | |
| Tgene | UPF3B | chrX:119602961 | chrX:118985836 | ENST00000276201 | 0 | 11 | 52_57 | 52 | 484.0 | Region | Note=Binds to UPF2 | |
| Tgene | UPF3B | chrX:119602961 | chrX:118985836 | ENST00000345865 | 0 | 10 | 424_483 | 52 | 471.0 | Region | Sufficient for association with EJC core | |
| Tgene | UPF3B | chrX:119602961 | chrX:118985836 | ENST00000345865 | 0 | 10 | 52_57 | 52 | 471.0 | Region | Note=Binds to UPF2 |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000200639 | - | 1 | 9 | 193_228 | 21 | 411.0 | Region | Note=Hinge |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000200639 | - | 1 | 9 | 229_375 | 21 | 411.0 | Region | Note=Second lumenal domain |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000200639 | - | 1 | 9 | 29_192 | 21 | 411.0 | Region | Note=First lumenal domain |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000371335 | - | 1 | 9 | 193_228 | 21 | 411.0 | Region | Note=Hinge |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000371335 | - | 1 | 9 | 229_375 | 21 | 411.0 | Region | Note=Second lumenal domain |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000371335 | - | 1 | 9 | 29_192 | 21 | 411.0 | Region | Note=First lumenal domain |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000434600 | - | 1 | 9 | 193_228 | 21 | 412.0 | Region | Note=Hinge |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000434600 | - | 1 | 9 | 229_375 | 21 | 412.0 | Region | Note=Second lumenal domain |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000434600 | - | 1 | 9 | 29_192 | 21 | 412.0 | Region | Note=First lumenal domain |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000200639 | - | 1 | 9 | 29_375 | 21 | 411.0 | Topological domain | Lumenal |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000200639 | - | 1 | 9 | 400_410 | 21 | 411.0 | Topological domain | Cytoplasmic |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000371335 | - | 1 | 9 | 29_375 | 21 | 411.0 | Topological domain | Lumenal |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000371335 | - | 1 | 9 | 400_410 | 21 | 411.0 | Topological domain | Cytoplasmic |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000434600 | - | 1 | 9 | 29_375 | 21 | 412.0 | Topological domain | Lumenal |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000434600 | - | 1 | 9 | 400_410 | 21 | 412.0 | Topological domain | Cytoplasmic |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000200639 | - | 1 | 9 | 376_399 | 21 | 411.0 | Transmembrane | Helical |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000371335 | - | 1 | 9 | 376_399 | 21 | 411.0 | Transmembrane | Helical |
| Hgene | LAMP2 | chrX:119602961 | chrX:118985836 | ENST00000434600 | - | 1 | 9 | 376_399 | 21 | 412.0 | Transmembrane | Helical |
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Fusion Gene Sequence for LAMP2-UPF3B |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >44000_44000_1_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000200639_UPF3B_chrX_118985836_ENST00000276201_length(transcript)=2353nt_BP=201nt CCGATTCCTGGCTTTTGCAAGGCTGTGGTCGGTGGTCATCAGTGCTCTTGACCCAGGTCCAGCGAGCCTTTTCCCTGGTGTTGCAGCTGT TGTTGTACCGCCGCCGTCGCCGCCGTCGCCGCCTGCTCTGCGGGGTCATGGTGTGCTTCCGCCTCTTCCCGGTTCCGGGCTCAGGGCTCG TTCTGGTCTGCCTAGTCCTGGGTGGTAATTCGAAGATTACCTCCCACTTTGACCAAGGAGCAGCTTCAGGAACATCTTCAACCTATGCCT GAGCATGATTATTTTGAGTTTTTTTCTAATGATACGAGTTTGTATCCTCATATGTATGCCAGAGCATACATCAACTTTAAAAACCAAGAG GACATTATTTTGTTCAGGGATCGCTTTGATGGTTATGTATTCCTTGACAATAAAGGTCAGGAATATCCCGCTATAGTAGAATTTGCACCT TTTCAAAAAGCTGCAAAAAAGAAGACTAAGAAAAGAGATACCAAAGTCGGGACTATCGATGATGATCCAGAATATAGAAAGTTTTTGGAA AGTTATGCCACAGATAATGAGAAAATGACATCTACTCCAGAGACACTGCTAGAGGAAATAGAAGCAAAAAATAGAGAATTAATAGCTAAA AAGACAACCCCACTTTTGAGCTTCCTGAAAAACAAGCAGAGAATGAGAGAAGAAAAGAGAGAAGAAAGGAGGAGGAGAGAAATAGAAAGA AAAAGACAAAGAGAAGAAGAGAGGAGGAAATGGAAAGAAGAAGAGAAACGAAAAAGGAAAGATATAGAAAAGCTAAAGAAGATAGACAGA ATTCCAGAAAGGGACAAATTAAAGGATGAACCAAAGATTAAGGTACACAGGTTTCTGTTACAAGCTGTGAATCAGAAAAATCTGCTCAAG AAGCCAGAAAAAGGAGATGAAAAAGAATTGGACAAAAGAGAAAAAGCCAAGAAATTGGACAAAGAGAATCTCAGTGATGAAAGAGCCAGT GGGCAAAGTTGTACATTGCCCAAGCGTTCTGATAGCGAACTTAAAGATGAAAAACCAAAGAGACCTGAAGATGAGAGCGGCAGAGACTAT AGGGAGAGGGAACGGGAATATGAACGAGATCAGGAGCGCATACTTCGAGAAAGAGAGAGGCTGAAGCGGCAAGAAGAAGAGCGCCGTAGG CAGAAGGAGCGCTATGAGAAAGAGAAGACTTTTAAGAGAAAAGAAGAAGAAATGAAAAAAGAGAAAGACACACTTCGGGATAAAGGAAAG AAGGCTGAAAGTACAGAATCAATAGGCAGCTCAGAAAAAACTGAAAAGAAAGAAGAAGTGGTCAAGAGAGATCGAATAAGAAACAAGGAT CGTCCAGCGATGCAGCTTTACCAACCAGGAGCTCGAAGCCGAAATCGACTCTGTCCCCCTGATGACAGCACCAAGTCTGGAGATTCAGCA GCAGAAAGGAAGCAGGAAAGTGGTATTAGCCATAGAAAAGAAGGAGGAGAGGAGTGATAAGTCCAGATGGCCTTAGGTGTCCTGACTGTC TAGGCAGCCAAAGAGCACACGTTAAGCAATCCAGAGGTGCCTTCAGGGCAAAGAATAGAGAGAAAGGGAGCCGCTGTGCTGGTGGGGTAC ACTGCAGAGGAGTAAGTCTTGTGTCAAAGCAGGAATCTGATCAGAGGTTCAGAATTGGAAGTACAATTTCATTGCTTTTGCAATTTCTAC AAATTAATTTTAAAGTGTCAGAAAAAGGTGACGGCAAGGACATGCATTGCAATTTGCAGGGGGAATTGTCAAGTGAGGACTTCATCACAT ATGACACGAGAGAAAAGTAAGAGCTGGTTCTAAAATCAAAAGCTGTTGTTCATCCTGAATTGAATTTTCTGAATTTGGGTGGAGCAGAGT CGCTTTGAAGCCTTGTTCCGATCTAATTCTATTGTATTGTTGATGATAAGTGTTGACATTGGGTAGTGTAGAAGCAACAAGCATGTCCTT GTAGTACAGGTACAGTGAAGGATAGAACACACTTTCGTTGATACAAAAATTTAAATAGTTATGTTACTTCTGTATCCAGTGTCCTAAAGT TTTAGGATTAGTTTTAGTTTTTTGTTTGCTTATATGAGCTTAGCGTAAAGAATATTTTTAAACTTCGTGTTTTGTCATCAGCATCTTTTC TATTAAGAGGTAAAATGTAGTCCTTGTTTGACTCTTGACAATCCAGTGTGTTTGATCTTAGGTCTCATGATCTGAGTGCATACCCTCTCC AGGAAGGAAACTGCACCAGTGTCTATTCCTGTTAAATAGCAACTTTTAGTCTCAGCTTGTTTCGTTTTGATGTCAATAAATAGTAACAGC >44000_44000_1_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000200639_UPF3B_chrX_118985836_ENST00000276201_length(amino acids)=422AA_BP= MTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDNKGQEYPAIVEFAPFQKAAKKKTKKRDTKV GTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK RKRKDIEKLKKIDRIPERDKLKDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKD EKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEK -------------------------------------------------------------- >44000_44000_2_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000200639_UPF3B_chrX_118985836_ENST00000345865_length(transcript)=2310nt_BP=201nt CCGATTCCTGGCTTTTGCAAGGCTGTGGTCGGTGGTCATCAGTGCTCTTGACCCAGGTCCAGCGAGCCTTTTCCCTGGTGTTGCAGCTGT TGTTGTACCGCCGCCGTCGCCGCCGTCGCCGCCTGCTCTGCGGGGTCATGGTGTGCTTCCGCCTCTTCCCGGTTCCGGGCTCAGGGCTCG TTCTGGTCTGCCTAGTCCTGGGTGGTAATTCGAAGATTACCTCCCACTTTGACCAAGGAGCAGCTTCAGGAACATCTTCAACCTATGCCT GAGCATGATTATTTTGAGTTTTTTTCTAATGATACGAGTTTGTATCCTCATATGTATGCCAGAGCATACATCAACTTTAAAAACCAAGAG GACATTATTTTGTTCAGGGATCGCTTTGATGGTTATGTATTCCTTGACAATAAAGGTCAGGAATATCCCGCTATAGTAGAATTTGCACCT TTTCAAAAAGCTGCAAAAAAGAAGACTAAGAAAAGAGATACCAAAGTCGGGACTATCGATGATGATCCAGAATATAGAAAGTTTTTGGAA AGTTATGCCACAGATAATGAGAAAATGACATCTACTCCAGAGACACTGCTAGAGGAAATAGAAGCAAAAAATAGAGAATTAATAGCTAAA AAGACAACCCCACTTTTGAGCTTCCTGAAAAACAAGCAGAGAATGAGAGAAGAAAAGAGAGAAGAAAGGAGGAGGAGAGAAATAGAAAGA AAAAGACAAAGAGAAGAAGAGAGGAGGAAATGGAAAGAAGAAGAGAAACGAAAAAGGAAAGATATAGAAAAGCTAAAGAAGATAGACAGA ATTCCAGAAAGGGACAAATTAAAGGATGAACCAAAGATTAAGCTGCTCAAGAAGCCAGAAAAAGGAGATGAAAAAGAATTGGACAAAAGA GAAAAAGCCAAGAAATTGGACAAAGAGAATCTCAGTGATGAAAGAGCCAGTGGGCAAAGTTGTACATTGCCCAAGCGTTCTGATAGCGAA CTTAAAGATGAAAAACCAAAGAGACCTGAAGATGAGAGCGGCAGAGACTATAGGGAGAGGGAACGGGAATATGAACGAGATCAGGAGCGC ATACTTCGAGAAAGAGAGAGGCTGAAGCGGCAAGAAGAAGAGCGCCGTAGGCAGAAGGAGCGCTATGAGAAAGAGAAGACTTTTAAGAGA AAAGAAGAAGAAATGAAAAAAGAGAAAGACACACTTCGGGATAAAGGAAAGAAGGCTGAAAGTACAGAATCAATAGGCAGCTCAGAAAAA ACTGAAAAGAAAGAAGAAGTGGTCAAGAGAGATCGAATAAGAAACAAGGATCGTCCAGCGATGCAGCTTTACCAACCAGGAGCTCGAAGC CGAAATCGACTCTGTCCCCCTGATGACAGCACCAAGTCTGGAGATTCAGCAGCAGAAAGGAAGCAGGAAAGTGGTATTAGCCATAGAAAA GAAGGAGGAGAGGAGTGATAAGTCCAGATGGCCTTAGGTGTCCTGACTGTCTAGGCAGCCAAAGAGCACACGTTAAGCAATCCAGAGGTG CCTTCAGGGCAAAGAATAGAGAGAAAGGGAGCCGCTGTGCTGGTGGGGTACACTGCAGAGGAGTAAGTCTTGTGTCAAAGCAGGAATCTG ATCAGAGGTTCAGAATTGGAAGTACAATTTCATTGCTTTTGCAATTTCTACAAATTAATTTTAAAGTGTCAGAAAAAGGTGACGGCAAGG ACATGCATTGCAATTTGCAGGGGGAATTGTCAAGTGAGGACTTCATCACATATGACACGAGAGAAAAGTAAGAGCTGGTTCTAAAATCAA AAGCTGTTGTTCATCCTGAATTGAATTTTCTGAATTTGGGTGGAGCAGAGTCGCTTTGAAGCCTTGTTCCGATCTAATTCTATTGTATTG TTGATGATAAGTGTTGACATTGGGTAGTGTAGAAGCAACAAGCATGTCCTTGTAGTACAGGTACAGTGAAGGATAGAACACACTTTCGTT GATACAAAAATTTAAATAGTTATGTTACTTCTGTATCCAGTGTCCTAAAGTTTTAGGATTAGTTTTAGTTTTTTGTTTGCTTATATGAGC TTAGCGTAAAGAATATTTTTAAACTTCGTGTTTTGTCATCAGCATCTTTTCTATTAAGAGGTAAAATGTAGTCCTTGTTTGACTCTTGAC AATCCAGTGTGTTTGATCTTAGGTCTCATGATCTGAGTGCATACCCTCTCCAGGAAGGAAACTGCACCAGTGTCTATTCCTGTTAAATAG >44000_44000_2_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000200639_UPF3B_chrX_118985836_ENST00000345865_length(amino acids)=409AA_BP= MTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDNKGQEYPAIVEFAPFQKAAKKKTKKRDTKV GTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK RKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRD YREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNK -------------------------------------------------------------- >44000_44000_3_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000371335_UPF3B_chrX_118985836_ENST00000276201_length(transcript)=2353nt_BP=201nt CCGATTCCTGGCTTTTGCAAGGCTGTGGTCGGTGGTCATCAGTGCTCTTGACCCAGGTCCAGCGAGCCTTTTCCCTGGTGTTGCAGCTGT TGTTGTACCGCCGCCGTCGCCGCCGTCGCCGCCTGCTCTGCGGGGTCATGGTGTGCTTCCGCCTCTTCCCGGTTCCGGGCTCAGGGCTCG TTCTGGTCTGCCTAGTCCTGGGTGGTAATTCGAAGATTACCTCCCACTTTGACCAAGGAGCAGCTTCAGGAACATCTTCAACCTATGCCT GAGCATGATTATTTTGAGTTTTTTTCTAATGATACGAGTTTGTATCCTCATATGTATGCCAGAGCATACATCAACTTTAAAAACCAAGAG GACATTATTTTGTTCAGGGATCGCTTTGATGGTTATGTATTCCTTGACAATAAAGGTCAGGAATATCCCGCTATAGTAGAATTTGCACCT TTTCAAAAAGCTGCAAAAAAGAAGACTAAGAAAAGAGATACCAAAGTCGGGACTATCGATGATGATCCAGAATATAGAAAGTTTTTGGAA AGTTATGCCACAGATAATGAGAAAATGACATCTACTCCAGAGACACTGCTAGAGGAAATAGAAGCAAAAAATAGAGAATTAATAGCTAAA AAGACAACCCCACTTTTGAGCTTCCTGAAAAACAAGCAGAGAATGAGAGAAGAAAAGAGAGAAGAAAGGAGGAGGAGAGAAATAGAAAGA AAAAGACAAAGAGAAGAAGAGAGGAGGAAATGGAAAGAAGAAGAGAAACGAAAAAGGAAAGATATAGAAAAGCTAAAGAAGATAGACAGA ATTCCAGAAAGGGACAAATTAAAGGATGAACCAAAGATTAAGGTACACAGGTTTCTGTTACAAGCTGTGAATCAGAAAAATCTGCTCAAG AAGCCAGAAAAAGGAGATGAAAAAGAATTGGACAAAAGAGAAAAAGCCAAGAAATTGGACAAAGAGAATCTCAGTGATGAAAGAGCCAGT GGGCAAAGTTGTACATTGCCCAAGCGTTCTGATAGCGAACTTAAAGATGAAAAACCAAAGAGACCTGAAGATGAGAGCGGCAGAGACTAT AGGGAGAGGGAACGGGAATATGAACGAGATCAGGAGCGCATACTTCGAGAAAGAGAGAGGCTGAAGCGGCAAGAAGAAGAGCGCCGTAGG CAGAAGGAGCGCTATGAGAAAGAGAAGACTTTTAAGAGAAAAGAAGAAGAAATGAAAAAAGAGAAAGACACACTTCGGGATAAAGGAAAG AAGGCTGAAAGTACAGAATCAATAGGCAGCTCAGAAAAAACTGAAAAGAAAGAAGAAGTGGTCAAGAGAGATCGAATAAGAAACAAGGAT CGTCCAGCGATGCAGCTTTACCAACCAGGAGCTCGAAGCCGAAATCGACTCTGTCCCCCTGATGACAGCACCAAGTCTGGAGATTCAGCA GCAGAAAGGAAGCAGGAAAGTGGTATTAGCCATAGAAAAGAAGGAGGAGAGGAGTGATAAGTCCAGATGGCCTTAGGTGTCCTGACTGTC TAGGCAGCCAAAGAGCACACGTTAAGCAATCCAGAGGTGCCTTCAGGGCAAAGAATAGAGAGAAAGGGAGCCGCTGTGCTGGTGGGGTAC ACTGCAGAGGAGTAAGTCTTGTGTCAAAGCAGGAATCTGATCAGAGGTTCAGAATTGGAAGTACAATTTCATTGCTTTTGCAATTTCTAC AAATTAATTTTAAAGTGTCAGAAAAAGGTGACGGCAAGGACATGCATTGCAATTTGCAGGGGGAATTGTCAAGTGAGGACTTCATCACAT ATGACACGAGAGAAAAGTAAGAGCTGGTTCTAAAATCAAAAGCTGTTGTTCATCCTGAATTGAATTTTCTGAATTTGGGTGGAGCAGAGT CGCTTTGAAGCCTTGTTCCGATCTAATTCTATTGTATTGTTGATGATAAGTGTTGACATTGGGTAGTGTAGAAGCAACAAGCATGTCCTT GTAGTACAGGTACAGTGAAGGATAGAACACACTTTCGTTGATACAAAAATTTAAATAGTTATGTTACTTCTGTATCCAGTGTCCTAAAGT TTTAGGATTAGTTTTAGTTTTTTGTTTGCTTATATGAGCTTAGCGTAAAGAATATTTTTAAACTTCGTGTTTTGTCATCAGCATCTTTTC TATTAAGAGGTAAAATGTAGTCCTTGTTTGACTCTTGACAATCCAGTGTGTTTGATCTTAGGTCTCATGATCTGAGTGCATACCCTCTCC AGGAAGGAAACTGCACCAGTGTCTATTCCTGTTAAATAGCAACTTTTAGTCTCAGCTTGTTTCGTTTTGATGTCAATAAATAGTAACAGC >44000_44000_3_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000371335_UPF3B_chrX_118985836_ENST00000276201_length(amino acids)=422AA_BP= MTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDNKGQEYPAIVEFAPFQKAAKKKTKKRDTKV GTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK RKRKDIEKLKKIDRIPERDKLKDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKD EKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEK -------------------------------------------------------------- >44000_44000_4_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000371335_UPF3B_chrX_118985836_ENST00000345865_length(transcript)=2310nt_BP=201nt CCGATTCCTGGCTTTTGCAAGGCTGTGGTCGGTGGTCATCAGTGCTCTTGACCCAGGTCCAGCGAGCCTTTTCCCTGGTGTTGCAGCTGT TGTTGTACCGCCGCCGTCGCCGCCGTCGCCGCCTGCTCTGCGGGGTCATGGTGTGCTTCCGCCTCTTCCCGGTTCCGGGCTCAGGGCTCG TTCTGGTCTGCCTAGTCCTGGGTGGTAATTCGAAGATTACCTCCCACTTTGACCAAGGAGCAGCTTCAGGAACATCTTCAACCTATGCCT GAGCATGATTATTTTGAGTTTTTTTCTAATGATACGAGTTTGTATCCTCATATGTATGCCAGAGCATACATCAACTTTAAAAACCAAGAG GACATTATTTTGTTCAGGGATCGCTTTGATGGTTATGTATTCCTTGACAATAAAGGTCAGGAATATCCCGCTATAGTAGAATTTGCACCT TTTCAAAAAGCTGCAAAAAAGAAGACTAAGAAAAGAGATACCAAAGTCGGGACTATCGATGATGATCCAGAATATAGAAAGTTTTTGGAA AGTTATGCCACAGATAATGAGAAAATGACATCTACTCCAGAGACACTGCTAGAGGAAATAGAAGCAAAAAATAGAGAATTAATAGCTAAA AAGACAACCCCACTTTTGAGCTTCCTGAAAAACAAGCAGAGAATGAGAGAAGAAAAGAGAGAAGAAAGGAGGAGGAGAGAAATAGAAAGA AAAAGACAAAGAGAAGAAGAGAGGAGGAAATGGAAAGAAGAAGAGAAACGAAAAAGGAAAGATATAGAAAAGCTAAAGAAGATAGACAGA ATTCCAGAAAGGGACAAATTAAAGGATGAACCAAAGATTAAGCTGCTCAAGAAGCCAGAAAAAGGAGATGAAAAAGAATTGGACAAAAGA GAAAAAGCCAAGAAATTGGACAAAGAGAATCTCAGTGATGAAAGAGCCAGTGGGCAAAGTTGTACATTGCCCAAGCGTTCTGATAGCGAA CTTAAAGATGAAAAACCAAAGAGACCTGAAGATGAGAGCGGCAGAGACTATAGGGAGAGGGAACGGGAATATGAACGAGATCAGGAGCGC ATACTTCGAGAAAGAGAGAGGCTGAAGCGGCAAGAAGAAGAGCGCCGTAGGCAGAAGGAGCGCTATGAGAAAGAGAAGACTTTTAAGAGA AAAGAAGAAGAAATGAAAAAAGAGAAAGACACACTTCGGGATAAAGGAAAGAAGGCTGAAAGTACAGAATCAATAGGCAGCTCAGAAAAA ACTGAAAAGAAAGAAGAAGTGGTCAAGAGAGATCGAATAAGAAACAAGGATCGTCCAGCGATGCAGCTTTACCAACCAGGAGCTCGAAGC CGAAATCGACTCTGTCCCCCTGATGACAGCACCAAGTCTGGAGATTCAGCAGCAGAAAGGAAGCAGGAAAGTGGTATTAGCCATAGAAAA GAAGGAGGAGAGGAGTGATAAGTCCAGATGGCCTTAGGTGTCCTGACTGTCTAGGCAGCCAAAGAGCACACGTTAAGCAATCCAGAGGTG CCTTCAGGGCAAAGAATAGAGAGAAAGGGAGCCGCTGTGCTGGTGGGGTACACTGCAGAGGAGTAAGTCTTGTGTCAAAGCAGGAATCTG ATCAGAGGTTCAGAATTGGAAGTACAATTTCATTGCTTTTGCAATTTCTACAAATTAATTTTAAAGTGTCAGAAAAAGGTGACGGCAAGG ACATGCATTGCAATTTGCAGGGGGAATTGTCAAGTGAGGACTTCATCACATATGACACGAGAGAAAAGTAAGAGCTGGTTCTAAAATCAA AAGCTGTTGTTCATCCTGAATTGAATTTTCTGAATTTGGGTGGAGCAGAGTCGCTTTGAAGCCTTGTTCCGATCTAATTCTATTGTATTG TTGATGATAAGTGTTGACATTGGGTAGTGTAGAAGCAACAAGCATGTCCTTGTAGTACAGGTACAGTGAAGGATAGAACACACTTTCGTT GATACAAAAATTTAAATAGTTATGTTACTTCTGTATCCAGTGTCCTAAAGTTTTAGGATTAGTTTTAGTTTTTTGTTTGCTTATATGAGC TTAGCGTAAAGAATATTTTTAAACTTCGTGTTTTGTCATCAGCATCTTTTCTATTAAGAGGTAAAATGTAGTCCTTGTTTGACTCTTGAC AATCCAGTGTGTTTGATCTTAGGTCTCATGATCTGAGTGCATACCCTCTCCAGGAAGGAAACTGCACCAGTGTCTATTCCTGTTAAATAG >44000_44000_4_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000371335_UPF3B_chrX_118985836_ENST00000345865_length(amino acids)=409AA_BP= MTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDNKGQEYPAIVEFAPFQKAAKKKTKKRDTKV GTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK RKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRD YREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNK -------------------------------------------------------------- >44000_44000_5_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000434600_UPF3B_chrX_118985836_ENST00000276201_length(transcript)=2412nt_BP=260nt GAGATTGGCTGTAAGCAAGAAAGAGCCCCGCCCCTAGTCTTATGACTCGCACTGAAGCGCCGATTCCTGGCTTTTGCAAGGCTGTGGTCG GTGGTCATCAGTGCTCTTGACCCAGGTCCAGCGAGCCTTTTCCCTGGTGTTGCAGCTGTTGTTGTACCGCCGCCGTCGCCGCCGTCGCCG CCTGCTCTGCGGGGTCATGGTGTGCTTCCGCCTCTTCCCGGTTCCGGGCTCAGGGCTCGTTCTGGTCTGCCTAGTCCTGGGTGGTAATTC GAAGATTACCTCCCACTTTGACCAAGGAGCAGCTTCAGGAACATCTTCAACCTATGCCTGAGCATGATTATTTTGAGTTTTTTTCTAATG ATACGAGTTTGTATCCTCATATGTATGCCAGAGCATACATCAACTTTAAAAACCAAGAGGACATTATTTTGTTCAGGGATCGCTTTGATG GTTATGTATTCCTTGACAATAAAGGTCAGGAATATCCCGCTATAGTAGAATTTGCACCTTTTCAAAAAGCTGCAAAAAAGAAGACTAAGA AAAGAGATACCAAAGTCGGGACTATCGATGATGATCCAGAATATAGAAAGTTTTTGGAAAGTTATGCCACAGATAATGAGAAAATGACAT CTACTCCAGAGACACTGCTAGAGGAAATAGAAGCAAAAAATAGAGAATTAATAGCTAAAAAGACAACCCCACTTTTGAGCTTCCTGAAAA ACAAGCAGAGAATGAGAGAAGAAAAGAGAGAAGAAAGGAGGAGGAGAGAAATAGAAAGAAAAAGACAAAGAGAAGAAGAGAGGAGGAAAT GGAAAGAAGAAGAGAAACGAAAAAGGAAAGATATAGAAAAGCTAAAGAAGATAGACAGAATTCCAGAAAGGGACAAATTAAAGGATGAAC CAAAGATTAAGGTACACAGGTTTCTGTTACAAGCTGTGAATCAGAAAAATCTGCTCAAGAAGCCAGAAAAAGGAGATGAAAAAGAATTGG ACAAAAGAGAAAAAGCCAAGAAATTGGACAAAGAGAATCTCAGTGATGAAAGAGCCAGTGGGCAAAGTTGTACATTGCCCAAGCGTTCTG ATAGCGAACTTAAAGATGAAAAACCAAAGAGACCTGAAGATGAGAGCGGCAGAGACTATAGGGAGAGGGAACGGGAATATGAACGAGATC AGGAGCGCATACTTCGAGAAAGAGAGAGGCTGAAGCGGCAAGAAGAAGAGCGCCGTAGGCAGAAGGAGCGCTATGAGAAAGAGAAGACTT TTAAGAGAAAAGAAGAAGAAATGAAAAAAGAGAAAGACACACTTCGGGATAAAGGAAAGAAGGCTGAAAGTACAGAATCAATAGGCAGCT CAGAAAAAACTGAAAAGAAAGAAGAAGTGGTCAAGAGAGATCGAATAAGAAACAAGGATCGTCCAGCGATGCAGCTTTACCAACCAGGAG CTCGAAGCCGAAATCGACTCTGTCCCCCTGATGACAGCACCAAGTCTGGAGATTCAGCAGCAGAAAGGAAGCAGGAAAGTGGTATTAGCC ATAGAAAAGAAGGAGGAGAGGAGTGATAAGTCCAGATGGCCTTAGGTGTCCTGACTGTCTAGGCAGCCAAAGAGCACACGTTAAGCAATC CAGAGGTGCCTTCAGGGCAAAGAATAGAGAGAAAGGGAGCCGCTGTGCTGGTGGGGTACACTGCAGAGGAGTAAGTCTTGTGTCAAAGCA GGAATCTGATCAGAGGTTCAGAATTGGAAGTACAATTTCATTGCTTTTGCAATTTCTACAAATTAATTTTAAAGTGTCAGAAAAAGGTGA CGGCAAGGACATGCATTGCAATTTGCAGGGGGAATTGTCAAGTGAGGACTTCATCACATATGACACGAGAGAAAAGTAAGAGCTGGTTCT AAAATCAAAAGCTGTTGTTCATCCTGAATTGAATTTTCTGAATTTGGGTGGAGCAGAGTCGCTTTGAAGCCTTGTTCCGATCTAATTCTA TTGTATTGTTGATGATAAGTGTTGACATTGGGTAGTGTAGAAGCAACAAGCATGTCCTTGTAGTACAGGTACAGTGAAGGATAGAACACA CTTTCGTTGATACAAAAATTTAAATAGTTATGTTACTTCTGTATCCAGTGTCCTAAAGTTTTAGGATTAGTTTTAGTTTTTTGTTTGCTT ATATGAGCTTAGCGTAAAGAATATTTTTAAACTTCGTGTTTTGTCATCAGCATCTTTTCTATTAAGAGGTAAAATGTAGTCCTTGTTTGA CTCTTGACAATCCAGTGTGTTTGATCTTAGGTCTCATGATCTGAGTGCATACCCTCTCCAGGAAGGAAACTGCACCAGTGTCTATTCCTG >44000_44000_5_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000434600_UPF3B_chrX_118985836_ENST00000276201_length(amino acids)=422AA_BP= MTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDNKGQEYPAIVEFAPFQKAAKKKTKKRDTKV GTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK RKRKDIEKLKKIDRIPERDKLKDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKD EKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEK -------------------------------------------------------------- >44000_44000_6_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000434600_UPF3B_chrX_118985836_ENST00000345865_length(transcript)=2369nt_BP=260nt GAGATTGGCTGTAAGCAAGAAAGAGCCCCGCCCCTAGTCTTATGACTCGCACTGAAGCGCCGATTCCTGGCTTTTGCAAGGCTGTGGTCG GTGGTCATCAGTGCTCTTGACCCAGGTCCAGCGAGCCTTTTCCCTGGTGTTGCAGCTGTTGTTGTACCGCCGCCGTCGCCGCCGTCGCCG CCTGCTCTGCGGGGTCATGGTGTGCTTCCGCCTCTTCCCGGTTCCGGGCTCAGGGCTCGTTCTGGTCTGCCTAGTCCTGGGTGGTAATTC GAAGATTACCTCCCACTTTGACCAAGGAGCAGCTTCAGGAACATCTTCAACCTATGCCTGAGCATGATTATTTTGAGTTTTTTTCTAATG ATACGAGTTTGTATCCTCATATGTATGCCAGAGCATACATCAACTTTAAAAACCAAGAGGACATTATTTTGTTCAGGGATCGCTTTGATG GTTATGTATTCCTTGACAATAAAGGTCAGGAATATCCCGCTATAGTAGAATTTGCACCTTTTCAAAAAGCTGCAAAAAAGAAGACTAAGA AAAGAGATACCAAAGTCGGGACTATCGATGATGATCCAGAATATAGAAAGTTTTTGGAAAGTTATGCCACAGATAATGAGAAAATGACAT CTACTCCAGAGACACTGCTAGAGGAAATAGAAGCAAAAAATAGAGAATTAATAGCTAAAAAGACAACCCCACTTTTGAGCTTCCTGAAAA ACAAGCAGAGAATGAGAGAAGAAAAGAGAGAAGAAAGGAGGAGGAGAGAAATAGAAAGAAAAAGACAAAGAGAAGAAGAGAGGAGGAAAT GGAAAGAAGAAGAGAAACGAAAAAGGAAAGATATAGAAAAGCTAAAGAAGATAGACAGAATTCCAGAAAGGGACAAATTAAAGGATGAAC CAAAGATTAAGCTGCTCAAGAAGCCAGAAAAAGGAGATGAAAAAGAATTGGACAAAAGAGAAAAAGCCAAGAAATTGGACAAAGAGAATC TCAGTGATGAAAGAGCCAGTGGGCAAAGTTGTACATTGCCCAAGCGTTCTGATAGCGAACTTAAAGATGAAAAACCAAAGAGACCTGAAG ATGAGAGCGGCAGAGACTATAGGGAGAGGGAACGGGAATATGAACGAGATCAGGAGCGCATACTTCGAGAAAGAGAGAGGCTGAAGCGGC AAGAAGAAGAGCGCCGTAGGCAGAAGGAGCGCTATGAGAAAGAGAAGACTTTTAAGAGAAAAGAAGAAGAAATGAAAAAAGAGAAAGACA CACTTCGGGATAAAGGAAAGAAGGCTGAAAGTACAGAATCAATAGGCAGCTCAGAAAAAACTGAAAAGAAAGAAGAAGTGGTCAAGAGAG ATCGAATAAGAAACAAGGATCGTCCAGCGATGCAGCTTTACCAACCAGGAGCTCGAAGCCGAAATCGACTCTGTCCCCCTGATGACAGCA CCAAGTCTGGAGATTCAGCAGCAGAAAGGAAGCAGGAAAGTGGTATTAGCCATAGAAAAGAAGGAGGAGAGGAGTGATAAGTCCAGATGG CCTTAGGTGTCCTGACTGTCTAGGCAGCCAAAGAGCACACGTTAAGCAATCCAGAGGTGCCTTCAGGGCAAAGAATAGAGAGAAAGGGAG CCGCTGTGCTGGTGGGGTACACTGCAGAGGAGTAAGTCTTGTGTCAAAGCAGGAATCTGATCAGAGGTTCAGAATTGGAAGTACAATTTC ATTGCTTTTGCAATTTCTACAAATTAATTTTAAAGTGTCAGAAAAAGGTGACGGCAAGGACATGCATTGCAATTTGCAGGGGGAATTGTC AAGTGAGGACTTCATCACATATGACACGAGAGAAAAGTAAGAGCTGGTTCTAAAATCAAAAGCTGTTGTTCATCCTGAATTGAATTTTCT GAATTTGGGTGGAGCAGAGTCGCTTTGAAGCCTTGTTCCGATCTAATTCTATTGTATTGTTGATGATAAGTGTTGACATTGGGTAGTGTA GAAGCAACAAGCATGTCCTTGTAGTACAGGTACAGTGAAGGATAGAACACACTTTCGTTGATACAAAAATTTAAATAGTTATGTTACTTC TGTATCCAGTGTCCTAAAGTTTTAGGATTAGTTTTAGTTTTTTGTTTGCTTATATGAGCTTAGCGTAAAGAATATTTTTAAACTTCGTGT TTTGTCATCAGCATCTTTTCTATTAAGAGGTAAAATGTAGTCCTTGTTTGACTCTTGACAATCCAGTGTGTTTGATCTTAGGTCTCATGA TCTGAGTGCATACCCTCTCCAGGAAGGAAACTGCACCAGTGTCTATTCCTGTTAAATAGCAACTTTTAGTCTCAGCTTGTTTCGTTTTGA >44000_44000_6_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000434600_UPF3B_chrX_118985836_ENST00000345865_length(amino acids)=409AA_BP= MTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDNKGQEYPAIVEFAPFQKAAKKKTKKRDTKV GTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK RKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRD YREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNK -------------------------------------------------------------- >44000_44000_7_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000538785_UPF3B_chrX_118985836_ENST00000276201_length(transcript)=2376nt_BP=224nt GTCTTATGACTCGCACTGAAGCGCCGATTCCTGGCTTTTGCAAGGCTGTGGTCGGTGGTCATCAGTGCTCTTGACCCAGGTCCAGCGAGC CTTTTCCCTGGTGTTGCAGCTGTTGTTGTACCGCCGCCGTCGCCGCCGTCGCCGCCTGCTCTGCGGGGTCATGGTGTGCTTCCGCCTCTT CCCGGTTCCGGGCTCAGGGCTCGTTCTGGTCTGCCTAGTCCTGGGTGGTAATTCGAAGATTACCTCCCACTTTGACCAAGGAGCAGCTTC AGGAACATCTTCAACCTATGCCTGAGCATGATTATTTTGAGTTTTTTTCTAATGATACGAGTTTGTATCCTCATATGTATGCCAGAGCAT ACATCAACTTTAAAAACCAAGAGGACATTATTTTGTTCAGGGATCGCTTTGATGGTTATGTATTCCTTGACAATAAAGGTCAGGAATATC CCGCTATAGTAGAATTTGCACCTTTTCAAAAAGCTGCAAAAAAGAAGACTAAGAAAAGAGATACCAAAGTCGGGACTATCGATGATGATC CAGAATATAGAAAGTTTTTGGAAAGTTATGCCACAGATAATGAGAAAATGACATCTACTCCAGAGACACTGCTAGAGGAAATAGAAGCAA AAAATAGAGAATTAATAGCTAAAAAGACAACCCCACTTTTGAGCTTCCTGAAAAACAAGCAGAGAATGAGAGAAGAAAAGAGAGAAGAAA GGAGGAGGAGAGAAATAGAAAGAAAAAGACAAAGAGAAGAAGAGAGGAGGAAATGGAAAGAAGAAGAGAAACGAAAAAGGAAAGATATAG AAAAGCTAAAGAAGATAGACAGAATTCCAGAAAGGGACAAATTAAAGGATGAACCAAAGATTAAGGTACACAGGTTTCTGTTACAAGCTG TGAATCAGAAAAATCTGCTCAAGAAGCCAGAAAAAGGAGATGAAAAAGAATTGGACAAAAGAGAAAAAGCCAAGAAATTGGACAAAGAGA ATCTCAGTGATGAAAGAGCCAGTGGGCAAAGTTGTACATTGCCCAAGCGTTCTGATAGCGAACTTAAAGATGAAAAACCAAAGAGACCTG AAGATGAGAGCGGCAGAGACTATAGGGAGAGGGAACGGGAATATGAACGAGATCAGGAGCGCATACTTCGAGAAAGAGAGAGGCTGAAGC GGCAAGAAGAAGAGCGCCGTAGGCAGAAGGAGCGCTATGAGAAAGAGAAGACTTTTAAGAGAAAAGAAGAAGAAATGAAAAAAGAGAAAG ACACACTTCGGGATAAAGGAAAGAAGGCTGAAAGTACAGAATCAATAGGCAGCTCAGAAAAAACTGAAAAGAAAGAAGAAGTGGTCAAGA GAGATCGAATAAGAAACAAGGATCGTCCAGCGATGCAGCTTTACCAACCAGGAGCTCGAAGCCGAAATCGACTCTGTCCCCCTGATGACA GCACCAAGTCTGGAGATTCAGCAGCAGAAAGGAAGCAGGAAAGTGGTATTAGCCATAGAAAAGAAGGAGGAGAGGAGTGATAAGTCCAGA TGGCCTTAGGTGTCCTGACTGTCTAGGCAGCCAAAGAGCACACGTTAAGCAATCCAGAGGTGCCTTCAGGGCAAAGAATAGAGAGAAAGG GAGCCGCTGTGCTGGTGGGGTACACTGCAGAGGAGTAAGTCTTGTGTCAAAGCAGGAATCTGATCAGAGGTTCAGAATTGGAAGTACAAT TTCATTGCTTTTGCAATTTCTACAAATTAATTTTAAAGTGTCAGAAAAAGGTGACGGCAAGGACATGCATTGCAATTTGCAGGGGGAATT GTCAAGTGAGGACTTCATCACATATGACACGAGAGAAAAGTAAGAGCTGGTTCTAAAATCAAAAGCTGTTGTTCATCCTGAATTGAATTT TCTGAATTTGGGTGGAGCAGAGTCGCTTTGAAGCCTTGTTCCGATCTAATTCTATTGTATTGTTGATGATAAGTGTTGACATTGGGTAGT GTAGAAGCAACAAGCATGTCCTTGTAGTACAGGTACAGTGAAGGATAGAACACACTTTCGTTGATACAAAAATTTAAATAGTTATGTTAC TTCTGTATCCAGTGTCCTAAAGTTTTAGGATTAGTTTTAGTTTTTTGTTTGCTTATATGAGCTTAGCGTAAAGAATATTTTTAAACTTCG TGTTTTGTCATCAGCATCTTTTCTATTAAGAGGTAAAATGTAGTCCTTGTTTGACTCTTGACAATCCAGTGTGTTTGATCTTAGGTCTCA TGATCTGAGTGCATACCCTCTCCAGGAAGGAAACTGCACCAGTGTCTATTCCTGTTAAATAGCAACTTTTAGTCTCAGCTTGTTTCGTTT >44000_44000_7_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000538785_UPF3B_chrX_118985836_ENST00000276201_length(amino acids)=422AA_BP= MTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDNKGQEYPAIVEFAPFQKAAKKKTKKRDTKV GTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK RKRKDIEKLKKIDRIPERDKLKDEPKIKVHRFLLQAVNQKNLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKD EKPKRPEDESGRDYREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEK -------------------------------------------------------------- >44000_44000_8_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000538785_UPF3B_chrX_118985836_ENST00000345865_length(transcript)=2333nt_BP=224nt GTCTTATGACTCGCACTGAAGCGCCGATTCCTGGCTTTTGCAAGGCTGTGGTCGGTGGTCATCAGTGCTCTTGACCCAGGTCCAGCGAGC CTTTTCCCTGGTGTTGCAGCTGTTGTTGTACCGCCGCCGTCGCCGCCGTCGCCGCCTGCTCTGCGGGGTCATGGTGTGCTTCCGCCTCTT CCCGGTTCCGGGCTCAGGGCTCGTTCTGGTCTGCCTAGTCCTGGGTGGTAATTCGAAGATTACCTCCCACTTTGACCAAGGAGCAGCTTC AGGAACATCTTCAACCTATGCCTGAGCATGATTATTTTGAGTTTTTTTCTAATGATACGAGTTTGTATCCTCATATGTATGCCAGAGCAT ACATCAACTTTAAAAACCAAGAGGACATTATTTTGTTCAGGGATCGCTTTGATGGTTATGTATTCCTTGACAATAAAGGTCAGGAATATC CCGCTATAGTAGAATTTGCACCTTTTCAAAAAGCTGCAAAAAAGAAGACTAAGAAAAGAGATACCAAAGTCGGGACTATCGATGATGATC CAGAATATAGAAAGTTTTTGGAAAGTTATGCCACAGATAATGAGAAAATGACATCTACTCCAGAGACACTGCTAGAGGAAATAGAAGCAA AAAATAGAGAATTAATAGCTAAAAAGACAACCCCACTTTTGAGCTTCCTGAAAAACAAGCAGAGAATGAGAGAAGAAAAGAGAGAAGAAA GGAGGAGGAGAGAAATAGAAAGAAAAAGACAAAGAGAAGAAGAGAGGAGGAAATGGAAAGAAGAAGAGAAACGAAAAAGGAAAGATATAG AAAAGCTAAAGAAGATAGACAGAATTCCAGAAAGGGACAAATTAAAGGATGAACCAAAGATTAAGCTGCTCAAGAAGCCAGAAAAAGGAG ATGAAAAAGAATTGGACAAAAGAGAAAAAGCCAAGAAATTGGACAAAGAGAATCTCAGTGATGAAAGAGCCAGTGGGCAAAGTTGTACAT TGCCCAAGCGTTCTGATAGCGAACTTAAAGATGAAAAACCAAAGAGACCTGAAGATGAGAGCGGCAGAGACTATAGGGAGAGGGAACGGG AATATGAACGAGATCAGGAGCGCATACTTCGAGAAAGAGAGAGGCTGAAGCGGCAAGAAGAAGAGCGCCGTAGGCAGAAGGAGCGCTATG AGAAAGAGAAGACTTTTAAGAGAAAAGAAGAAGAAATGAAAAAAGAGAAAGACACACTTCGGGATAAAGGAAAGAAGGCTGAAAGTACAG AATCAATAGGCAGCTCAGAAAAAACTGAAAAGAAAGAAGAAGTGGTCAAGAGAGATCGAATAAGAAACAAGGATCGTCCAGCGATGCAGC TTTACCAACCAGGAGCTCGAAGCCGAAATCGACTCTGTCCCCCTGATGACAGCACCAAGTCTGGAGATTCAGCAGCAGAAAGGAAGCAGG AAAGTGGTATTAGCCATAGAAAAGAAGGAGGAGAGGAGTGATAAGTCCAGATGGCCTTAGGTGTCCTGACTGTCTAGGCAGCCAAAGAGC ACACGTTAAGCAATCCAGAGGTGCCTTCAGGGCAAAGAATAGAGAGAAAGGGAGCCGCTGTGCTGGTGGGGTACACTGCAGAGGAGTAAG TCTTGTGTCAAAGCAGGAATCTGATCAGAGGTTCAGAATTGGAAGTACAATTTCATTGCTTTTGCAATTTCTACAAATTAATTTTAAAGT GTCAGAAAAAGGTGACGGCAAGGACATGCATTGCAATTTGCAGGGGGAATTGTCAAGTGAGGACTTCATCACATATGACACGAGAGAAAA GTAAGAGCTGGTTCTAAAATCAAAAGCTGTTGTTCATCCTGAATTGAATTTTCTGAATTTGGGTGGAGCAGAGTCGCTTTGAAGCCTTGT TCCGATCTAATTCTATTGTATTGTTGATGATAAGTGTTGACATTGGGTAGTGTAGAAGCAACAAGCATGTCCTTGTAGTACAGGTACAGT GAAGGATAGAACACACTTTCGTTGATACAAAAATTTAAATAGTTATGTTACTTCTGTATCCAGTGTCCTAAAGTTTTAGGATTAGTTTTA GTTTTTTGTTTGCTTATATGAGCTTAGCGTAAAGAATATTTTTAAACTTCGTGTTTTGTCATCAGCATCTTTTCTATTAAGAGGTAAAAT GTAGTCCTTGTTTGACTCTTGACAATCCAGTGTGTTTGATCTTAGGTCTCATGATCTGAGTGCATACCCTCTCCAGGAAGGAAACTGCAC >44000_44000_8_LAMP2-UPF3B_LAMP2_chrX_119602961_ENST00000538785_UPF3B_chrX_118985836_ENST00000345865_length(amino acids)=409AA_BP= MTKEQLQEHLQPMPEHDYFEFFSNDTSLYPHMYARAYINFKNQEDIILFRDRFDGYVFLDNKGQEYPAIVEFAPFQKAAKKKTKKRDTKV GTIDDDPEYRKFLESYATDNEKMTSTPETLLEEIEAKNRELIAKKTTPLLSFLKNKQRMREEKREERRRREIERKRQREEERRKWKEEEK RKRKDIEKLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQSCTLPKRSDSELKDEKPKRPEDESGRD YREREREYERDQERILRERERLKRQEEERRRQKERYEKEKTFKRKEEEMKKEKDTLRDKGKKAESTESIGSSEKTEKKEEVVKRDRIRNK -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for LAMP2-UPF3B |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for LAMP2-UPF3B |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for LAMP2-UPF3B |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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