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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANKFY1-SPINT2 (FusionGDB2 ID:4432)

Fusion Gene Summary for ANKFY1-SPINT2

check button Fusion gene summary
Fusion gene informationFusion gene name: ANKFY1-SPINT2
Fusion gene ID: 4432
HgeneTgene
Gene symbol

ANKFY1

SPINT2

Gene ID

51479

10653

Gene nameankyrin repeat and FYVE domain containing 1serine peptidase inhibitor, Kunitz type 2
SynonymsANKHZN|BTBD23|ZFYVE14DIAR3|HAI-2|HAI2|Kop|PB
Cytomap

17p13.2

19q13.2

Type of geneprotein-codingprotein-coding
Descriptionrabankyrin-5Rabankyrin-5ankyrin repeat and FYVE domain-containing protein 1ankyrin repeat hooked to zinc finger motifankyrin repeats hooked to a zinc finger motifrank-5kunitz-type protease inhibitor 2hepatocyte growth factor activator inhibitor type 2serine protease inhibitor, Kunitz type, 2testicular tissue protein Li 183
Modification date2020031320200315
UniProtAcc

Q9P2R3

.
Ensembl transtripts involved in fusion geneENST00000341657, ENST00000570535, 
ENST00000574367, ENST00000433651, 
ENST00000573722, 		ENST00000587090, 
ENST00000454580, ENST00000301244, 
Fusion gene scores* DoF score8 X 9 X 7=50411 X 6 X 8=528
# samples 1213
** MAII scorelog2(12/504*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(13/528*10)=-2.02202630633
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANKFY1 [Title/Abstract] AND SPINT2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANKFY1(4077204)-SPINT2(38774267), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANKFY1

GO:0034058

endosomal vesicle fusion

15328530

HgeneANKFY1

GO:0048549

positive regulation of pinocytosis

15328530

TgeneSPINT2

GO:0022408

negative regulation of cell-cell adhesion

19592578

TgeneSPINT2

GO:2000146

negative regulation of cell motility

19592578


check buttonFusion gene breakpoints across ANKFY1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across SPINT2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-25-1632-01AANKFY1chr17

4077204

-SPINT2chr19

38774267

+
ChimerDB4OVTCGA-25-1632ANKFY1chr17

4077203

-SPINT2chr19

38774266

+


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Fusion Gene ORF analysis for ANKFY1-SPINT2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000341657ENST00000587090ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
5CDS-5UTRENST00000341657ENST00000587090ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
5CDS-5UTRENST00000570535ENST00000587090ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
5CDS-5UTRENST00000570535ENST00000587090ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
5CDS-5UTRENST00000574367ENST00000587090ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
5CDS-5UTRENST00000574367ENST00000587090ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
5CDS-intronENST00000341657ENST00000454580ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
5CDS-intronENST00000341657ENST00000454580ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
5CDS-intronENST00000570535ENST00000454580ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
5CDS-intronENST00000570535ENST00000454580ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
5CDS-intronENST00000574367ENST00000454580ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
5CDS-intronENST00000574367ENST00000454580ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
In-frameENST00000341657ENST00000301244ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
In-frameENST00000341657ENST00000301244ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
In-frameENST00000570535ENST00000301244ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
In-frameENST00000570535ENST00000301244ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
In-frameENST00000574367ENST00000301244ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
In-frameENST00000574367ENST00000301244ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
intron-3CDSENST00000433651ENST00000301244ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
intron-3CDSENST00000433651ENST00000301244ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
intron-3CDSENST00000573722ENST00000301244ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
intron-3CDSENST00000573722ENST00000301244ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
intron-5UTRENST00000433651ENST00000587090ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
intron-5UTRENST00000433651ENST00000587090ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
intron-5UTRENST00000573722ENST00000587090ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
intron-5UTRENST00000573722ENST00000587090ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
intron-intronENST00000433651ENST00000454580ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
intron-intronENST00000433651ENST00000454580ANKFY1chr17

4077203

-SPINT2chr19

38774266

+
intron-intronENST00000573722ENST00000454580ANKFY1chr17

4077204

-SPINT2chr19

38774267

+
intron-intronENST00000573722ENST00000454580ANKFY1chr17

4077203

-SPINT2chr19

38774266

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000341657ANKFY1chr174077204-ENST00000301244SPINT2chr1938774267+422029593636111191
ENST00000570535ANKFY1chr174077204-ENST00000301244SPINT2chr1938774267+4427316611738181233
ENST00000574367ANKFY1chr174077204-ENST00000301244SPINT2chr1938774267+420229411535931192
ENST00000341657ANKFY1chr174077203-ENST00000301244SPINT2chr1938774266+422029593636111191
ENST00000570535ANKFY1chr174077203-ENST00000301244SPINT2chr1938774266+4427316611738181233
ENST00000574367ANKFY1chr174077203-ENST00000301244SPINT2chr1938774266+420229411535931192

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000341657ENST00000301244ANKFY1chr174077204-SPINT2chr1938774267+0.0029445620.9970554
ENST00000570535ENST00000301244ANKFY1chr174077204-SPINT2chr1938774267+0.0031649260.99683505
ENST00000574367ENST00000301244ANKFY1chr174077204-SPINT2chr1938774267+0.0024778370.9975222
ENST00000341657ENST00000301244ANKFY1chr174077203-SPINT2chr1938774266+0.0029445620.9970554
ENST00000570535ENST00000301244ANKFY1chr174077203-SPINT2chr1938774266+0.0031649260.99683505
ENST00000574367ENST00000301244ANKFY1chr174077203-SPINT2chr1938774266+0.0024778370.9975222

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Fusion Genomic Features for ANKFY1-SPINT2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANKFY1chr174077203-SPINT2chr1938774266+1.58E-050.99998426
ANKFY1chr174077203-SPINT2chr1938774266+1.58E-050.99998426
ANKFY1chr174077203-SPINT2chr1938774266+1.58E-050.99998426
ANKFY1chr174077203-SPINT2chr1938774266+1.58E-050.99998426

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANKFY1-SPINT2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr17:4077204/chr19:38774267)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANKFY1

Q9P2R3

.
FUNCTION: Proposed effector of Rab5. Binds to phosphatidylinositol 3-phosphate (PI(3)P). Involved in homotypic early endosome fusion and to a lesser extent in heterotypic fusion of chlathrin-coated vesicles with early endosomes. Involved in macropinocytosis; the function is dependent on Rab5-GTP. Required for correct endosomal localization. Involved in the internalization and trafficking of activated tyrosine kinase receptors such as PDGFRB. Regulates the subcellular localization of the retromer complex in a EHD1-dependent manner. Involved in endosome-to-Golgi transport and biosynthetic transport to late endosomes and lysosomes indicative for a regulation of retromer complex-mediated retrograde transport. {ECO:0000269|PubMed:15328530, ECO:0000269|PubMed:22284051, ECO:0000269|PubMed:24102721}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-202568_1309741170.0DomainBTB
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-202568_13010161212.0DomainBTB
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-202568_1309751171.0DomainBTB
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-202568_1309741170.0DomainBTB
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-202568_13010161212.0DomainBTB
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-202568_1309751171.0DomainBTB
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025217_2479741170.0RepeatNote=ANK 1
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025255_2849741170.0RepeatNote=ANK 2
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025288_3179741170.0RepeatNote=ANK 3
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025322_3629741170.0RepeatNote=ANK 4
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025366_3969741170.0RepeatNote=ANK 5
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025490_5199741170.0RepeatNote=ANK 6
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025542_5729741170.0RepeatNote=ANK 7
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025588_6179741170.0RepeatNote=ANK 8
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025621_6509741170.0RepeatNote=ANK 9
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025654_6839741170.0RepeatNote=ANK 10
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025687_7169741170.0RepeatNote=ANK 11
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025724_7539741170.0RepeatNote=ANK 12
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025769_7989741170.0RepeatNote=ANK 13
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025802_8329741170.0RepeatNote=ANK 14
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025836_8659741170.0RepeatNote=ANK 15
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025870_8999741170.0RepeatNote=ANK 16
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025905_9349741170.0RepeatNote=ANK 17
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025938_9679741170.0RepeatNote=ANK 18
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025217_24710161212.0RepeatNote=ANK 1
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025255_28410161212.0RepeatNote=ANK 2
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025288_31710161212.0RepeatNote=ANK 3
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025322_36210161212.0RepeatNote=ANK 4
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025366_39610161212.0RepeatNote=ANK 5
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025490_51910161212.0RepeatNote=ANK 6
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025542_57210161212.0RepeatNote=ANK 7
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025588_61710161212.0RepeatNote=ANK 8
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025621_65010161212.0RepeatNote=ANK 9
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025654_68310161212.0RepeatNote=ANK 10
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025687_71610161212.0RepeatNote=ANK 11
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025724_75310161212.0RepeatNote=ANK 12
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025769_79810161212.0RepeatNote=ANK 13
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025802_83210161212.0RepeatNote=ANK 14
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025836_86510161212.0RepeatNote=ANK 15
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025870_89910161212.0RepeatNote=ANK 16
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025905_93410161212.0RepeatNote=ANK 17
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025938_96710161212.0RepeatNote=ANK 18
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025971_100110161212.0RepeatNote=ANK 19
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025217_2479751171.0RepeatNote=ANK 1
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025255_2849751171.0RepeatNote=ANK 2
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025288_3179751171.0RepeatNote=ANK 3
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025322_3629751171.0RepeatNote=ANK 4
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025366_3969751171.0RepeatNote=ANK 5
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025490_5199751171.0RepeatNote=ANK 6
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025542_5729751171.0RepeatNote=ANK 7
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025588_6179751171.0RepeatNote=ANK 8
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025621_6509751171.0RepeatNote=ANK 9
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025654_6839751171.0RepeatNote=ANK 10
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025687_7169751171.0RepeatNote=ANK 11
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025724_7539751171.0RepeatNote=ANK 12
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025769_7989751171.0RepeatNote=ANK 13
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025802_8329751171.0RepeatNote=ANK 14
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025836_8659751171.0RepeatNote=ANK 15
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025870_8999751171.0RepeatNote=ANK 16
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025905_9349751171.0RepeatNote=ANK 17
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025938_9679751171.0RepeatNote=ANK 18
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025217_2479741170.0RepeatNote=ANK 1
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025255_2849741170.0RepeatNote=ANK 2
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025288_3179741170.0RepeatNote=ANK 3
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025322_3629741170.0RepeatNote=ANK 4
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025366_3969741170.0RepeatNote=ANK 5
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025490_5199741170.0RepeatNote=ANK 6
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025542_5729741170.0RepeatNote=ANK 7
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025588_6179741170.0RepeatNote=ANK 8
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025621_6509741170.0RepeatNote=ANK 9
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025654_6839741170.0RepeatNote=ANK 10
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025687_7169741170.0RepeatNote=ANK 11
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025724_7539741170.0RepeatNote=ANK 12
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025769_7989741170.0RepeatNote=ANK 13
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025802_8329741170.0RepeatNote=ANK 14
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025836_8659741170.0RepeatNote=ANK 15
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025870_8999741170.0RepeatNote=ANK 16
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025905_9349741170.0RepeatNote=ANK 17
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025938_9679741170.0RepeatNote=ANK 18
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025217_24710161212.0RepeatNote=ANK 1
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025255_28410161212.0RepeatNote=ANK 2
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025288_31710161212.0RepeatNote=ANK 3
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025322_36210161212.0RepeatNote=ANK 4
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025366_39610161212.0RepeatNote=ANK 5
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025490_51910161212.0RepeatNote=ANK 6
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025542_57210161212.0RepeatNote=ANK 7
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025588_61710161212.0RepeatNote=ANK 8
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025621_65010161212.0RepeatNote=ANK 9
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025654_68310161212.0RepeatNote=ANK 10
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025687_71610161212.0RepeatNote=ANK 11
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025724_75310161212.0RepeatNote=ANK 12
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025769_79810161212.0RepeatNote=ANK 13
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025802_83210161212.0RepeatNote=ANK 14
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025836_86510161212.0RepeatNote=ANK 15
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025870_89910161212.0RepeatNote=ANK 16
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025905_93410161212.0RepeatNote=ANK 17
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025938_96710161212.0RepeatNote=ANK 18
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025971_100110161212.0RepeatNote=ANK 19
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025217_2479751171.0RepeatNote=ANK 1
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025255_2849751171.0RepeatNote=ANK 2
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025288_3179751171.0RepeatNote=ANK 3
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025322_3629751171.0RepeatNote=ANK 4
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025366_3969751171.0RepeatNote=ANK 5
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025490_5199751171.0RepeatNote=ANK 6
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025542_5729751171.0RepeatNote=ANK 7
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025588_6179751171.0RepeatNote=ANK 8
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025621_6509751171.0RepeatNote=ANK 9
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025654_6839751171.0RepeatNote=ANK 10
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025687_7169751171.0RepeatNote=ANK 11
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025724_7539751171.0RepeatNote=ANK 12
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025769_7989751171.0RepeatNote=ANK 13
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025802_8329751171.0RepeatNote=ANK 14
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025836_8659751171.0RepeatNote=ANK 15
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025870_8999751171.0RepeatNote=ANK 16
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025905_9349751171.0RepeatNote=ANK 17
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025938_9679751171.0RepeatNote=ANK 18
TgeneSPINT2chr17:4077203chr19:38774266ENST0000030124407219_25235253.0Topological domainCytoplasmic
TgeneSPINT2chr17:4077203chr19:38774266ENST0000045458006219_2520196.0Topological domainCytoplasmic
TgeneSPINT2chr17:4077203chr19:38774266ENST000004545800628_1970196.0Topological domainExtracellular
TgeneSPINT2chr17:4077204chr19:38774267ENST0000030124407219_25235253.0Topological domainCytoplasmic
TgeneSPINT2chr17:4077204chr19:38774267ENST0000045458006219_2520196.0Topological domainCytoplasmic
TgeneSPINT2chr17:4077204chr19:38774267ENST000004545800628_1970196.0Topological domainExtracellular
TgeneSPINT2chr17:4077203chr19:38774266ENST0000030124407198_21835253.0TransmembraneHelical
TgeneSPINT2chr17:4077203chr19:38774266ENST0000045458006198_2180196.0TransmembraneHelical
TgeneSPINT2chr17:4077204chr19:38774267ENST0000030124407198_21835253.0TransmembraneHelical
TgeneSPINT2chr17:4077204chr19:38774267ENST0000045458006198_2180196.0TransmembraneHelical

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-11068_1300488.0DomainBTB
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-11068_1300488.0DomainBTB
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-20251005_10379741170.0RepeatNote=ANK 20
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-20251043_10729741170.0RepeatNote=ANK 21
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025971_10019741170.0RepeatNote=ANK 19
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-1101005_10370488.0RepeatNote=ANK 20
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-1101043_10720488.0RepeatNote=ANK 21
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110217_2470488.0RepeatNote=ANK 1
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110255_2840488.0RepeatNote=ANK 2
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110288_3170488.0RepeatNote=ANK 3
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110322_3620488.0RepeatNote=ANK 4
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110366_3960488.0RepeatNote=ANK 5
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110490_5190488.0RepeatNote=ANK 6
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110542_5720488.0RepeatNote=ANK 7
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110588_6170488.0RepeatNote=ANK 8
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110621_6500488.0RepeatNote=ANK 9
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110654_6830488.0RepeatNote=ANK 10
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110687_7160488.0RepeatNote=ANK 11
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110724_7530488.0RepeatNote=ANK 12
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110769_7980488.0RepeatNote=ANK 13
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110802_8320488.0RepeatNote=ANK 14
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110836_8650488.0RepeatNote=ANK 15
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110870_8990488.0RepeatNote=ANK 16
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110905_9340488.0RepeatNote=ANK 17
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110938_9670488.0RepeatNote=ANK 18
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110971_10010488.0RepeatNote=ANK 19
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-20251005_103710161212.0RepeatNote=ANK 20
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-20251043_107210161212.0RepeatNote=ANK 21
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-20251005_10379751171.0RepeatNote=ANK 20
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-20251043_10729751171.0RepeatNote=ANK 21
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025971_10019751171.0RepeatNote=ANK 19
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-20251005_10379741170.0RepeatNote=ANK 20
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-20251043_10729741170.0RepeatNote=ANK 21
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025971_10019741170.0RepeatNote=ANK 19
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-1101005_10370488.0RepeatNote=ANK 20
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-1101043_10720488.0RepeatNote=ANK 21
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110217_2470488.0RepeatNote=ANK 1
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110255_2840488.0RepeatNote=ANK 2
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110288_3170488.0RepeatNote=ANK 3
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110322_3620488.0RepeatNote=ANK 4
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110366_3960488.0RepeatNote=ANK 5
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110490_5190488.0RepeatNote=ANK 6
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110542_5720488.0RepeatNote=ANK 7
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110588_6170488.0RepeatNote=ANK 8
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110621_6500488.0RepeatNote=ANK 9
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110654_6830488.0RepeatNote=ANK 10
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110687_7160488.0RepeatNote=ANK 11
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110724_7530488.0RepeatNote=ANK 12
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110769_7980488.0RepeatNote=ANK 13
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110802_8320488.0RepeatNote=ANK 14
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110836_8650488.0RepeatNote=ANK 15
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110870_8990488.0RepeatNote=ANK 16
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110905_9340488.0RepeatNote=ANK 17
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110938_9670488.0RepeatNote=ANK 18
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110971_10010488.0RepeatNote=ANK 19
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-20251005_103710161212.0RepeatNote=ANK 20
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-20251043_107210161212.0RepeatNote=ANK 21
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-20251005_10379751171.0RepeatNote=ANK 20
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-20251043_10729751171.0RepeatNote=ANK 21
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025971_10019751171.0RepeatNote=ANK 19
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-20251104_11649741170.0Zinc fingerFYVE-type
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-1101104_11640488.0Zinc fingerFYVE-type
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-20251104_116410161212.0Zinc fingerFYVE-type
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-20251104_11649751171.0Zinc fingerFYVE-type
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-20251104_11649741170.0Zinc fingerFYVE-type
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-1101104_11640488.0Zinc fingerFYVE-type
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-20251104_116410161212.0Zinc fingerFYVE-type
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-20251104_11649751171.0Zinc fingerFYVE-type
TgeneSPINT2chr17:4077203chr19:38774266ENST000003012440728_19735253.0Topological domainExtracellular
TgeneSPINT2chr17:4077204chr19:38774267ENST000003012440728_19735253.0Topological domainExtracellular


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Fusion Gene Sequence for ANKFY1-SPINT2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4432_4432_1_ANKFY1-SPINT2_ANKFY1_chr17_4077203_ENST00000341657_SPINT2_chr19_38774266_ENST00000301244_length(transcript)=4220nt_BP=2959nt
ACTTCTCGCGAGGTTGCAGGCAGTGCCGGGCCAGACATGGCGGAAGAGGAGGTGGCCAAGTTGGAGAAGCACTTGATGCTTCTGCGGCAG
GAGTATGTCAAGCTGCAGAAGAAGCTGGCGGAGACAGAGAAGCGCTGCGCTCTCTTGGCTGCGCAGGCAAACAAGGAGAGCAGCAGCGAG
TCCTTCATCAGCCGTCTGCTGGCCATCGTGGCAGACCTCTACGAGCAGGAGCAGTACAGCGATCTGAAGATAAAGGTTGGGGACAGGCAC
ATCAGTGCTCACAAGTTTGTCCTGGCAGCCCGCAGTGACAGCTGGAGTCTGGCTAACTTGTCTTCCACTAAAGAGTTGGACCTGTCAGAT
GCTAATCCTGAGGTGACGATGACAATGCTTCGCTGGATCTATACAGATGAGCTGGAGTTCAGAGAGGATGATGTGTTCCTGACTGAACTG
ATGAAACTAGCAAATCGGTTTCAGCTACAGCTCCTCAGGGAGAGATGTGAGAAGGGTGTTATGTCTCTAGTGAATGTCAGGAACTGTATT
CGCTTCTACCAGACGGCAGAGGAGCTGAATGCCAGCACACTGATGAACTACTGTGCAGAAATTATTGCAAGTCATTGGGACGACCTGAGG
AAGGAGGATTTCAGCAGCATGAGCGCTCAGTTGTTATACAAAATGATCAAATCCAAGACAGAGTACCCGCTACATAAAGCCATCAAAGTG
GAGAGAGAAGACGTGGTCTTCCTGTATCTGATTGAAATGGATTCCCAGCTCCCTGGGAAGCTGAATGAAGCGGATCATAACGGAGATCTG
GCATTAGATCTAGCCCTCTCACGACGACTGGAGAGTATTGCCACCACGCTGGTTAGTCACAAAGCTGATGTGGACATGGTGGACAAGAGT
GGCTGGAGCTTGTTACACAAAGGAATCCAAAGAGGAGATCTCTTTGCTGCCACTTTCCTCATTAAGAATGGGGCCTTTGTCAACGCTGCT
ACACTGGGTGCCCAGGAGACACCACTGCACCTTGTGGCCTTGTACAGTTCAAAGAAACACTCAGCAGATGTGATGTCTGAGATGGCGCAG
ATTGCAGAGGCCCTTCTGCAGGCTGGTGCCAACCCCAACATGCAGGACAGCAAGGGGAGGACTCCTTTACATGTGTCCATCATGGCCGGG
AATGAATATGTGTTCAGTCAGCTGCTGCAGTGCAAACAACTAGATTTAGAACTCAAAGACCACGAGGGCAGCACGGCTCTGTGGCTGGCA
GTGCAGCATATCACAGTGTCTTCTGACCAGTCTGTGAACCCCTTCGAAGATGTCCCCGTGGTAAATGGGACTTCATTTGATGAGAACAGC
TTTGCAGCCAGACTCATCCAGCGCGGCAGCCACACAGACGCACCTGACACGGCGACAGGAAACTGTTTACTACAGCGGGCAGCTGGAGCA
GGAAACGAGGCAGCAGCTCTTTTCCTGGCAACCAACGGTGCCCATGTCAACCACAGAAACAAGTGGGGAGAAACCCCGTTGCACACAGCG
TGTCGGCATGGCCTGGCCAACCTCACGGCAGAGCTCCTGCAGCAAGGCGCCAACCCAAACCTGCAGACGGAGGAAGCTCTGCCTCTGCCA
AAGGAGGCCGCATCCCTGACCAGCTTGGCGGACAGCGTCCATCTGCAGACGCCACTGCACATGGCGATCGCCTATAACCATCCGGATGTG
GTGTCTGTCATCCTGGAGCAGAAAGCCAATGCTCTTCATGCCACCAACAACTTGCAGATCATTCCGGACTTCAGCCTCAAAGATTCCCGA
GACCAGACTGTGCTGGGCCTGGCATTATGGACTGGCATGCACACGATCGCAGCCCAGCTGCTGGGCTCTGGAGCCGCCATCAATGACACC
ATGTCGGATGGGCAGACGCTACTGCACATGGCCATACAGCGGCAGGACAGCAAGAGCGCACTCTTCCTGCTGGAGCACCAGGCAGATATA
AATGTCAGGACTCAGGACGGGGAGACAGCCCTCCAGCTGGCCATCAGAAACCAGCTTCCACTCGTAGTTGATGCCATATGCACCCGAGGA
GCTGACATGTCTGTGCCAGATGAGAAGGGGAACCCCCCGCTGTGGCTTGCATTGGCAAACAATCTGGAGGACATCGCATCCACTCTGGTC
AGACATGGCTGTGATGCCACATGCTGGGGTCCGGGACCTGGTGGGTGCCTTCAGACGCTCCTGCACAGAGCCATTGATGAAAACAACGAG
CCCACCGCCTGCTTTCTTATTCGCAGTGGCTGTGACGTGAACAGTCCCAGACAACCAGGCGCCAATGGAGAAGGAGAGGAAGAGGCTAGA
GATGGGCAGACCCCTTTGCATTTGGCAGCCTCTTGGGGGCTGGAAGAGACAGTACAGTGTCTTCTGGAGTTTGGTGCCAACGTGAACGCA
CAGGATGCAGAAGGAAGAACCCCCATCCACGTGGCCATCAGCAGCCAACACGGTGTCATCATTCAGCTGTTGGTTTCTCACCCCGATATC
CATTTGAATGTACGAGACAGACAAGGGCTGACCCCGTTTGCCTGTGCCATGACTTTCAAGAACAACAAGTCAGCCGAGGCCATTCTCAAA
CGAGAGTCCGGGGCTGCTGAGCAGGTGGATAACAAGGGCCGGAATTTCCTTCATGTGGCAGTTCAGAACTCTGATATTGAAAGTGTGCTG
TTCCTGATCAGTGTCCACGCTAATGTGAATTCAAGAGTCCAGGATGCCTCCAAGTTGACCCCCCTGCACCTCGCTGTCCAAGCAGGCTCA
GAAATTATTGTCCGCAATTTGCTTCTTGCGGGAGCCAAAGTGAACGAATTAACCAAGCATCGCCAGACTGCCCTCCATCTTGCTGCCCAG
CAGGACCTGCCCACCATCTGCTCAGTCCTCCTAGAGAATGGCGTGGACTTTGCTGCCGTGGATGAGAATGGAAACAATGACTTCTGCCTG
GTGTCGAAGGTGGTGGGCAGATGCCGGGCCTCCATGCCTAGGTGGTGGTACAATGTCACTGACGGATCCTGCCAGCTGTTTGTGTATGGG
GGCTGTGACGGAAACAGCAATAATTACCTGACCAAGGAGGAGTGCCTCAAGAAATGTGCCACTGTCACAGAGAATGCCACGGGTGACCTG
GCCACCAGCAGGAATGCAGCGGATTCCTCTGTCCCAAGTGCTCCCAGAAGGCAGGATTCTGAAGACCACTCCAGCGATATGTTCAACTAT
GAAGAATACTGCACCGCCAACGCAGTCACTGGGCCTTGCCGTGCATCCTTCCCACGCTGGTACTTTGACGTGGAGAGGAACTCCTGCAAT
AACTTCATCTATGGAGGCTGCCGGGGCAATAAGAACAGCTACCGCTCTGAGGAGGCCTGCATGCTCCGCTGCTTCCGCCAGCAGGAGAAT
CCTCCCCTGCCCCTTGGCTCAAAGGTGGTGGTTCTGGCGGGGCTGTTCGTGATGGTGTTGATCCTCTTCCTGGGAGCCTCCATGGTCTAC
CTGATCCGGGTGGCACGGAGGAACCAGGAGCGTGCCCTGCGCACCGTCTGGAGCTCCGGAGATGACAAGGAGCAGCTGGTGAAGAACACA
TATGTCCTGTGACCGCCCTGTCGCCAAGAGGACTGGGGAAGGGAGGGGAGACTATGTGTGAGCTTTTTTTAAATAGAGGGATTGACTCGG
ATTTGAGTGATCATTAGGGCTGAGGTCTGTTTCTCTGGGAGGTAGGACGGCTGCTTCCTGGTCTGGCAGGGATGGGTTTGCTTTGGAAAT
CCTCTAGGAGGCTCCTCCTCGCATGGCCTGCAGTCTGGCAGCAGCCCCGAGTTGTTTCCTCGCTGATCGATTTCTTTCCTCCAGGTAGAG
TTTTCTTTGCTTATGTTGAATTCCATTGCCTCTTTTCTCATCACAGAAGTGATGTTGGAATCGTTTCTTTTGTTTGTCTGATTTATGGTT
TTTTTAAGTATAAACAAAAGTTTTTTATTAGCATTCTGAAAGAAGGAAAGTAAAATGTACAAGTTTAATAAAAAGGGGCCTTCCCCTTTA
GAATAAATTTCAGCATGTGCTTTCTTTATGGGAGTCCTAATTTCAACCCTACCAAAATGATCACAAGACACTATCTGAGGTGTCCCATTC

>4432_4432_1_ANKFY1-SPINT2_ANKFY1_chr17_4077203_ENST00000341657_SPINT2_chr19_38774266_ENST00000301244_length(amino acids)=1191AA_BP=974
MAEEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARS
DSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNAS
TLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLES
IATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANP
NMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQHITVSSDQSVNPFEDVPVVNGTSFDENSFAARLIQRGSHT
DAPDTATGNCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADS
VHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAI
QRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPG
PGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVA
ISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSR
VQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNDFCLVSKVVGRCRASM
PRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGP
CRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQERA

--------------------------------------------------------------
>4432_4432_2_ANKFY1-SPINT2_ANKFY1_chr17_4077203_ENST00000570535_SPINT2_chr19_38774266_ENST00000301244_length(transcript)=4427nt_BP=3166nt
GGCCGGGCGTGGTTGCATGGGGGCTCCGCGGGTCTCGCGAGCCTTCCTGTCTAGCCTCTCCGGAGCTTCTCGGGCCGGGGTCCGGAGCGC
GGTTCCTATGACAACGTCCCTCCCGCGATGCCGACCCCGCGGGACTGCGGCCGGCTGCGGAGCCGGGCTGGCAGGTCCCGCGCCGGTGCT
GCGTGCAGCCGCGGGGCCCCGAGGGCAGCACGGGAGGCTCTTGATTGCCGGCGGTGCCGGGACGCCGGGGGAAAGGAGGTGGCCAAGTTG
GAGAAGCACTTGATGCTTCTGCGGCAGGAGTATGTCAAGCTGCAGAAGAAGCTGGCGGAGACAGAGAAGCGCTGCGCTCTCTTGGCTGCG
CAGGCAAACAAGGAGAGCAGCAGCGAGTCCTTCATCAGCCGTCTGCTGGCCATCGTGGCAGACCTCTACGAGCAGGAGCAGTACAGCGAT
CTGAAGATAAAGGTTGGGGACAGGCACATCAGTGCTCACAAGTTTGTCCTGGCAGCCCGCAGTGACAGCTGGAGTCTGGCTAACTTGTCT
TCCACTAAAGAGTTGGACCTGTCAGATGCTAATCCTGAGGTGACGATGACAATGCTTCGCTGGATCTATACAGATGAGCTGGAGTTCAGA
GAGGATGATGTGTTCCTGACTGAACTGATGAAACTAGCAAATCGGTTTCAGCTACAGCTCCTCAGGGAGAGATGTGAGAAGGGTGTTATG
TCTCTAGTGAATGTCAGGAACTGTATTCGCTTCTACCAGACGGCAGAGGAGCTGAATGCCAGCACACTGATGAACTACTGTGCAGAAATT
ATTGCAAGTCATTGGGACGACCTGAGGAAGGAGGATTTCAGCAGCATGAGCGCTCAGTTGTTATACAAAATGATCAAATCCAAGACAGAG
TACCCGCTACATAAAGCCATCAAAGTGGAGAGAGAAGACGTGGTCTTCCTGTATCTGATTGAAATGGATTCCCAGCTCCCTGGGAAGCTG
AATGAAGCGGATCATAACGGAGATCTGGCATTAGATCTAGCCCTCTCACGACGACTGGAGAGTATTGCCACCACGCTGGTTAGTCACAAA
GCTGATGTGGACATGGTGGACAAGAGTGGCTGGAGCTTGTTACACAAAGGAATCCAAAGAGGAGATCTCTTTGCTGCCACTTTCCTCATT
AAGAATGGGGCCTTTGTCAACGCTGCTACACTGGGTGCCCAGGAGACACCACTGCACCTTGTGGCCTTGTACAGTTCAAAGAAACACTCA
GCAGATGTGATGTCTGAGATGGCGCAGATTGCAGAGGCCCTTCTGCAGGCTGGTGCCAACCCCAACATGCAGGACAGCAAGGGGAGGACT
CCTTTACATGTGTCCATCATGGCCGGGAATGAATATGTGTTCAGTCAGCTGCTGCAGTGCAAACAACTAGATTTAGAACTCAAAGACCAC
GAGGGCAGCACGGCTCTGTGGCTGGCAGTGCAGCATATCACAGTGTCTTCTGACCAGTCTGTGAACCCCTTCGAAGATGTCCCCGTGGTA
AATGGGACTTCATTTGATGAGAACAGCTTTGCAGCCAGACTCATCCAGCGCGGCAGCCACACAGACGCACCTGACACGGCGACAGGAAAC
TGTTTACTACAGCGGGCAGCTGGAGCAGGAAACGAGGCAGCAGCTCTTTTCCTGGCAACCAACGGTGCCCATGTCAACCACAGAAACAAG
TGGGGAGAAACCCCGTTGCACACAGCGTGTCGGCATGGCCTGGCCAACCTCACGGCAGAGCTCCTGCAGCAAGGCGCCAACCCAAACCTG
CAGACGGAGGAAGCTCTGCCTCTGCCAAAGGAGGCCGCATCCCTGACCAGCTTGGCGGACAGCGTCCATCTGCAGACGCCACTGCACATG
GCGATCGCCTATAACCATCCGGATGTGGTGTCTGTCATCCTGGAGCAGAAAGCCAATGCTCTTCATGCCACCAACAACTTGCAGATCATT
CCGGACTTCAGCCTCAAAGATTCCCGAGACCAGACTGTGCTGGGCCTGGCATTATGGACTGGCATGCACACGATCGCAGCCCAGCTGCTG
GGCTCTGGAGCCGCCATCAATGACACCATGTCGGATGGGCAGACGCTACTGCACATGGCCATACAGCGGCAGGACAGCAAGAGCGCACTC
TTCCTGCTGGAGCACCAGGCAGATATAAATGTCAGGACTCAGGACGGGGAGACAGCCCTCCAGCTGGCCATCAGAAACCAGCTTCCACTC
GTAGTTGATGCCATATGCACCCGAGGAGCTGACATGTCTGTGCCAGATGAGAAGGGGAACCCCCCGCTGTGGCTTGCATTGGCAAACAAT
CTGGAGGACATCGCATCCACTCTGGTCAGACATGGCTGTGATGCCACATGCTGGGGTCCGGGACCTGGTGGGTGCCTTCAGACGCTCCTG
CACAGAGCCATTGATGAAAACAACGAGCCCACCGCCTGCTTTCTTATTCGCAGTGGCTGTGACGTGAACAGTCCCAGACAACCAGGCGCC
AATGGAGAAGGAGAGGAAGAGGCTAGAGATGGGCAGACCCCTTTGCATTTGGCAGCCTCTTGGGGGCTGGAAGAGACAGTACAGTGTCTT
CTGGAGTTTGGTGCCAACGTGAACGCACAGGATGCAGAAGGAAGAACCCCCATCCACGTGGCCATCAGCAGCCAACACGGTGTCATCATT
CAGCTGTTGGTTTCTCACCCCGATATCCATTTGAATGTACGAGACAGACAAGGGCTGACCCCGTTTGCCTGTGCCATGACTTTCAAGAAC
AACAAGTCAGCCGAGGCCATTCTCAAACGAGAGTCCGGGGCTGCTGAGCAGGTGGATAACAAGGGCCGGAATTTCCTTCATGTGGCAGTT
CAGAACTCTGATATTGAAAGTGTGCTGTTCCTGATCAGTGTCCACGCTAATGTGAATTCAAGAGTCCAGGATGCCTCCAAGTTGACCCCC
CTGCACCTCGCTGTCCAAGCAGGCTCAGAAATTATTGTCCGCAATTTGCTTCTTGCGGGAGCCAAAGTGAACGAATTAACCAAGCATCGC
CAGACTGCCCTCCATCTTGCTGCCCAGCAGGACCTGCCCACCATCTGCTCAGTCCTCCTAGAGAATGGCGTGGACTTTGCTGCCGTGGAT
GAGAATGGAAACAATGACTTCTGCCTGGTGTCGAAGGTGGTGGGCAGATGCCGGGCCTCCATGCCTAGGTGGTGGTACAATGTCACTGAC
GGATCCTGCCAGCTGTTTGTGTATGGGGGCTGTGACGGAAACAGCAATAATTACCTGACCAAGGAGGAGTGCCTCAAGAAATGTGCCACT
GTCACAGAGAATGCCACGGGTGACCTGGCCACCAGCAGGAATGCAGCGGATTCCTCTGTCCCAAGTGCTCCCAGAAGGCAGGATTCTGAA
GACCACTCCAGCGATATGTTCAACTATGAAGAATACTGCACCGCCAACGCAGTCACTGGGCCTTGCCGTGCATCCTTCCCACGCTGGTAC
TTTGACGTGGAGAGGAACTCCTGCAATAACTTCATCTATGGAGGCTGCCGGGGCAATAAGAACAGCTACCGCTCTGAGGAGGCCTGCATG
CTCCGCTGCTTCCGCCAGCAGGAGAATCCTCCCCTGCCCCTTGGCTCAAAGGTGGTGGTTCTGGCGGGGCTGTTCGTGATGGTGTTGATC
CTCTTCCTGGGAGCCTCCATGGTCTACCTGATCCGGGTGGCACGGAGGAACCAGGAGCGTGCCCTGCGCACCGTCTGGAGCTCCGGAGAT
GACAAGGAGCAGCTGGTGAAGAACACATATGTCCTGTGACCGCCCTGTCGCCAAGAGGACTGGGGAAGGGAGGGGAGACTATGTGTGAGC
TTTTTTTAAATAGAGGGATTGACTCGGATTTGAGTGATCATTAGGGCTGAGGTCTGTTTCTCTGGGAGGTAGGACGGCTGCTTCCTGGTC
TGGCAGGGATGGGTTTGCTTTGGAAATCCTCTAGGAGGCTCCTCCTCGCATGGCCTGCAGTCTGGCAGCAGCCCCGAGTTGTTTCCTCGC
TGATCGATTTCTTTCCTCCAGGTAGAGTTTTCTTTGCTTATGTTGAATTCCATTGCCTCTTTTCTCATCACAGAAGTGATGTTGGAATCG
TTTCTTTTGTTTGTCTGATTTATGGTTTTTTTAAGTATAAACAAAAGTTTTTTATTAGCATTCTGAAAGAAGGAAAGTAAAATGTACAAG
TTTAATAAAAAGGGGCCTTCCCCTTTAGAATAAATTTCAGCATGTGCTTTCTTTATGGGAGTCCTAATTTCAACCCTACCAAAATGATCA
CAAGACACTATCTGAGGTGTCCCATTCTAGAAATAGACCCCTCAAAATAGCGTCTTTCAGATCTTTTTGAATGAATCCACAAGATGAAAT

>4432_4432_2_ANKFY1-SPINT2_ANKFY1_chr17_4077203_ENST00000570535_SPINT2_chr19_38774266_ENST00000301244_length(amino acids)=1233AA_BP=1016
MPTPRDCGRLRSRAGRSRAGAACSRGAPRAAREALDCRRCRDAGGKEVAKLEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSE
SFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTEL
MKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKV
EREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAA
TLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLA
VQHITVSSDQSVNPFEDVPVVNGTSFDENSFAARLIQRGSHTDAPDTATGNCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTA
CRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSR
DQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRG
ADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEAR
DGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILK
RESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQ
QDLPTICSVLLENGVDFAAVDENGNNDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDL
ATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQEN

--------------------------------------------------------------
>4432_4432_3_ANKFY1-SPINT2_ANKFY1_chr17_4077203_ENST00000574367_SPINT2_chr19_38774266_ENST00000301244_length(transcript)=4202nt_BP=2941nt
AGTGCCGGGCCAGACATGGCGGAAGAGGAGGTGGCCAAGTTGGAGAAGCACTTGATGCTTCTGCGGCAGGAGTATGTCAAGCTGCAGAAG
AAGCTGGCGGAGACAGAGAAGCGCTGCGCTCTCTTGGCTGCGCAGGCAAACAAGGAGAGCAGCAGCGAGTCCTTCATCAGCCGTCTGCTG
GCCATCGTGGCAGACCTCTACGAGCAGGAGCAGTACAGCGATCTGAAGATAAAGGTTGGGGACAGGCACATCAGTGCTCACAAGTTTGTC
CTGGCAGCCCGCAGTGACAGCTGGAGTCTGGCTAACTTGTCTTCCACTAAAGAGTTGGACCTGTCAGATGCTAATCCTGAGGTGACGATG
ACAATGCTTCGCTGGATCTATACAGATGAGCTGGAGTTCAGAGAGGATGATGTGTTCCTGACTGAACTGATGAAACTAGCAAATCGGTTT
CAGCTACAGCTCCTCAGGGAGAGATGTGAGAAGGGTGTTATGTCTCTAGTGAATGTCAGGAACTGTATTCGCTTCTACCAGACGGCAGAG
GAGCTGAATGCCAGCACACTGATGAACTACTGTGCAGAAATTATTGCAAGTCATTGGGACGACCTGAGGAAGGAGGATTTCAGCAGCATG
AGCGCTCAGTTGTTATACAAAATGATCAAATCCAAGACAGAGTACCCGCTACATAAAGCCATCAAAGTGGAGAGAGAAGACGTGGTCTTC
CTGTATCTGATTGAAATGGATTCCCAGCTCCCTGGGAAGCTGAATGAAGCGGATCATAACGGAGATCTGGCATTAGATCTAGCCCTCTCA
CGACGACTGGAGAGTATTGCCACCACGCTGGTTAGTCACAAAGCTGATGTGGACATGGTGGACAAGAGTGGCTGGAGCTTGTTACACAAA
GGAATCCAAAGAGGAGATCTCTTTGCTGCCACTTTCCTCATTAAGAATGGGGCCTTTGTCAACGCTGCTACACTGGGTGCCCAGGAGACA
CCACTGCACCTTGTGGCCTTGTACAGTTCAAAGAAACACTCAGCAGATGTGATGTCTGAGATGGCGCAGATTGCAGAGGCCCTTCTGCAG
GCTGGTGCCAACCCCAACATGCAGGACAGCAAGGGGAGGACTCCTTTACATGTGTCCATCATGGCCGGGAATGAATATGTGTTCAGTCAG
CTGCTGCAGTGCAAACAACTAGATTTAGAACTCAAAGACCACGAGGGCAGCACGGCTCTGTGGCTGGCAGTGCAGCATATCACAGTGTCT
TCTGACCAGTCTGTGAACCCCTTCGAAGATGTCCCCGTGGTAAATGGGACTTCATTTGATGAGAACAGCTTTGCAGCCAGACTCATCCAG
CGCGGCAGCCACACAGACGCACCTGACACGGCGACAGGAAACTGTTTACTACAGCGGGCAGCTGGAGCAGGAAACGAGGCAGCAGCTCTT
TTCCTGGCAACCAACGGTGCCCATGTCAACCACAGAAACAAGTGGGGAGAAACCCCGTTGCACACAGCGTGTCGGCATGGCCTGGCCAAC
CTCACGGCAGAGCTCCTGCAGCAAGGCGCCAACCCAAACCTGCAGACGGAGGAAGCTCTGCCTCTGCCAAAGGAGGCCGCATCCCTGACC
AGCTTGGCGGACAGCGTCCATCTGCAGACGCCACTGCACATGGCGATCGCCTATAACCATCCGGATGTGGTGTCTGTCATCCTGGAGCAG
AAAGCCAATGCTCTTCATGCCACCAACAACTTGCAGATCATTCCGGACTTCAGCCTCAAAGATTCCCGAGACCAGACTGTGCTGGGCCTG
GCATTATGGACTGGCATGCACACGATCGCAGCCCAGCTGCTGGGCTCTGGAGCCGCCATCAATGACACCATGTCGGATGGGCAGACGCTA
CTGCACATGGCCATACAGCGGCAGGACAGCAAGAGCGCACTCTTCCTGCTGGAGCACCAGGCAGATATAAATGTCAGCAGGACTCAGGAC
GGGGAGACAGCCCTCCAGCTGGCCATCAGAAACCAGCTTCCACTCGTAGTTGATGCCATATGCACCCGAGGAGCTGACATGTCTGTGCCA
GATGAGAAGGGGAACCCCCCGCTGTGGCTTGCATTGGCAAACAATCTGGAGGACATCGCATCCACTCTGGTCAGACATGGCTGTGATGCC
ACATGCTGGGGTCCGGGACCTGGTGGGTGCCTTCAGACGCTCCTGCACAGAGCCATTGATGAAAACAACGAGCCCACCGCCTGCTTTCTT
ATTCGCAGTGGCTGTGACGTGAACAGTCCCAGACAACCAGGCGCCAATGGAGAAGGAGAGGAAGAGGCTAGAGATGGGCAGACCCCTTTG
CATTTGGCAGCCTCTTGGGGGCTGGAAGAGACAGTACAGTGTCTTCTGGAGTTTGGTGCCAACGTGAACGCACAGGATGCAGAAGGAAGA
ACCCCCATCCACGTGGCCATCAGCAGCCAACACGGTGTCATCATTCAGCTGTTGGTTTCTCACCCCGATATCCATTTGAATGTACGAGAC
AGACAAGGGCTGACCCCGTTTGCCTGTGCCATGACTTTCAAGAACAACAAGTCAGCCGAGGCCATTCTCAAACGAGAGTCCGGGGCTGCT
GAGCAGGTGGATAACAAGGGCCGGAATTTCCTTCATGTGGCAGTTCAGAACTCTGATATTGAAAGTGTGCTGTTCCTGATCAGTGTCCAC
GCTAATGTGAATTCAAGAGTCCAGGATGCCTCCAAGTTGACCCCCCTGCACCTCGCTGTCCAAGCAGGCTCAGAAATTATTGTCCGCAAT
TTGCTTCTTGCGGGAGCCAAAGTGAACGAATTAACCAAGCATCGCCAGACTGCCCTCCATCTTGCTGCCCAGCAGGACCTGCCCACCATC
TGCTCAGTCCTCCTAGAGAATGGCGTGGACTTTGCTGCCGTGGATGAGAATGGAAACAATGACTTCTGCCTGGTGTCGAAGGTGGTGGGC
AGATGCCGGGCCTCCATGCCTAGGTGGTGGTACAATGTCACTGACGGATCCTGCCAGCTGTTTGTGTATGGGGGCTGTGACGGAAACAGC
AATAATTACCTGACCAAGGAGGAGTGCCTCAAGAAATGTGCCACTGTCACAGAGAATGCCACGGGTGACCTGGCCACCAGCAGGAATGCA
GCGGATTCCTCTGTCCCAAGTGCTCCCAGAAGGCAGGATTCTGAAGACCACTCCAGCGATATGTTCAACTATGAAGAATACTGCACCGCC
AACGCAGTCACTGGGCCTTGCCGTGCATCCTTCCCACGCTGGTACTTTGACGTGGAGAGGAACTCCTGCAATAACTTCATCTATGGAGGC
TGCCGGGGCAATAAGAACAGCTACCGCTCTGAGGAGGCCTGCATGCTCCGCTGCTTCCGCCAGCAGGAGAATCCTCCCCTGCCCCTTGGC
TCAAAGGTGGTGGTTCTGGCGGGGCTGTTCGTGATGGTGTTGATCCTCTTCCTGGGAGCCTCCATGGTCTACCTGATCCGGGTGGCACGG
AGGAACCAGGAGCGTGCCCTGCGCACCGTCTGGAGCTCCGGAGATGACAAGGAGCAGCTGGTGAAGAACACATATGTCCTGTGACCGCCC
TGTCGCCAAGAGGACTGGGGAAGGGAGGGGAGACTATGTGTGAGCTTTTTTTAAATAGAGGGATTGACTCGGATTTGAGTGATCATTAGG
GCTGAGGTCTGTTTCTCTGGGAGGTAGGACGGCTGCTTCCTGGTCTGGCAGGGATGGGTTTGCTTTGGAAATCCTCTAGGAGGCTCCTCC
TCGCATGGCCTGCAGTCTGGCAGCAGCCCCGAGTTGTTTCCTCGCTGATCGATTTCTTTCCTCCAGGTAGAGTTTTCTTTGCTTATGTTG
AATTCCATTGCCTCTTTTCTCATCACAGAAGTGATGTTGGAATCGTTTCTTTTGTTTGTCTGATTTATGGTTTTTTTAAGTATAAACAAA
AGTTTTTTATTAGCATTCTGAAAGAAGGAAAGTAAAATGTACAAGTTTAATAAAAAGGGGCCTTCCCCTTTAGAATAAATTTCAGCATGT
GCTTTCTTTATGGGAGTCCTAATTTCAACCCTACCAAAATGATCACAAGACACTATCTGAGGTGTCCCATTCTAGAAATAGACCCCTCAA

>4432_4432_3_ANKFY1-SPINT2_ANKFY1_chr17_4077203_ENST00000574367_SPINT2_chr19_38774266_ENST00000301244_length(amino acids)=1192AA_BP=975
MAEEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARS
DSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNAS
TLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLES
IATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANP
NMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQHITVSSDQSVNPFEDVPVVNGTSFDENSFAARLIQRGSHT
DAPDTATGNCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADS
VHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAI
QRQDSKSALFLLEHQADINVSRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGP
GPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHV
AISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNS
RVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNDFCLVSKVVGRCRAS
MPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTG
PCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQER

--------------------------------------------------------------
>4432_4432_4_ANKFY1-SPINT2_ANKFY1_chr17_4077204_ENST00000341657_SPINT2_chr19_38774267_ENST00000301244_length(transcript)=4220nt_BP=2959nt
ACTTCTCGCGAGGTTGCAGGCAGTGCCGGGCCAGACATGGCGGAAGAGGAGGTGGCCAAGTTGGAGAAGCACTTGATGCTTCTGCGGCAG
GAGTATGTCAAGCTGCAGAAGAAGCTGGCGGAGACAGAGAAGCGCTGCGCTCTCTTGGCTGCGCAGGCAAACAAGGAGAGCAGCAGCGAG
TCCTTCATCAGCCGTCTGCTGGCCATCGTGGCAGACCTCTACGAGCAGGAGCAGTACAGCGATCTGAAGATAAAGGTTGGGGACAGGCAC
ATCAGTGCTCACAAGTTTGTCCTGGCAGCCCGCAGTGACAGCTGGAGTCTGGCTAACTTGTCTTCCACTAAAGAGTTGGACCTGTCAGAT
GCTAATCCTGAGGTGACGATGACAATGCTTCGCTGGATCTATACAGATGAGCTGGAGTTCAGAGAGGATGATGTGTTCCTGACTGAACTG
ATGAAACTAGCAAATCGGTTTCAGCTACAGCTCCTCAGGGAGAGATGTGAGAAGGGTGTTATGTCTCTAGTGAATGTCAGGAACTGTATT
CGCTTCTACCAGACGGCAGAGGAGCTGAATGCCAGCACACTGATGAACTACTGTGCAGAAATTATTGCAAGTCATTGGGACGACCTGAGG
AAGGAGGATTTCAGCAGCATGAGCGCTCAGTTGTTATACAAAATGATCAAATCCAAGACAGAGTACCCGCTACATAAAGCCATCAAAGTG
GAGAGAGAAGACGTGGTCTTCCTGTATCTGATTGAAATGGATTCCCAGCTCCCTGGGAAGCTGAATGAAGCGGATCATAACGGAGATCTG
GCATTAGATCTAGCCCTCTCACGACGACTGGAGAGTATTGCCACCACGCTGGTTAGTCACAAAGCTGATGTGGACATGGTGGACAAGAGT
GGCTGGAGCTTGTTACACAAAGGAATCCAAAGAGGAGATCTCTTTGCTGCCACTTTCCTCATTAAGAATGGGGCCTTTGTCAACGCTGCT
ACACTGGGTGCCCAGGAGACACCACTGCACCTTGTGGCCTTGTACAGTTCAAAGAAACACTCAGCAGATGTGATGTCTGAGATGGCGCAG
ATTGCAGAGGCCCTTCTGCAGGCTGGTGCCAACCCCAACATGCAGGACAGCAAGGGGAGGACTCCTTTACATGTGTCCATCATGGCCGGG
AATGAATATGTGTTCAGTCAGCTGCTGCAGTGCAAACAACTAGATTTAGAACTCAAAGACCACGAGGGCAGCACGGCTCTGTGGCTGGCA
GTGCAGCATATCACAGTGTCTTCTGACCAGTCTGTGAACCCCTTCGAAGATGTCCCCGTGGTAAATGGGACTTCATTTGATGAGAACAGC
TTTGCAGCCAGACTCATCCAGCGCGGCAGCCACACAGACGCACCTGACACGGCGACAGGAAACTGTTTACTACAGCGGGCAGCTGGAGCA
GGAAACGAGGCAGCAGCTCTTTTCCTGGCAACCAACGGTGCCCATGTCAACCACAGAAACAAGTGGGGAGAAACCCCGTTGCACACAGCG
TGTCGGCATGGCCTGGCCAACCTCACGGCAGAGCTCCTGCAGCAAGGCGCCAACCCAAACCTGCAGACGGAGGAAGCTCTGCCTCTGCCA
AAGGAGGCCGCATCCCTGACCAGCTTGGCGGACAGCGTCCATCTGCAGACGCCACTGCACATGGCGATCGCCTATAACCATCCGGATGTG
GTGTCTGTCATCCTGGAGCAGAAAGCCAATGCTCTTCATGCCACCAACAACTTGCAGATCATTCCGGACTTCAGCCTCAAAGATTCCCGA
GACCAGACTGTGCTGGGCCTGGCATTATGGACTGGCATGCACACGATCGCAGCCCAGCTGCTGGGCTCTGGAGCCGCCATCAATGACACC
ATGTCGGATGGGCAGACGCTACTGCACATGGCCATACAGCGGCAGGACAGCAAGAGCGCACTCTTCCTGCTGGAGCACCAGGCAGATATA
AATGTCAGGACTCAGGACGGGGAGACAGCCCTCCAGCTGGCCATCAGAAACCAGCTTCCACTCGTAGTTGATGCCATATGCACCCGAGGA
GCTGACATGTCTGTGCCAGATGAGAAGGGGAACCCCCCGCTGTGGCTTGCATTGGCAAACAATCTGGAGGACATCGCATCCACTCTGGTC
AGACATGGCTGTGATGCCACATGCTGGGGTCCGGGACCTGGTGGGTGCCTTCAGACGCTCCTGCACAGAGCCATTGATGAAAACAACGAG
CCCACCGCCTGCTTTCTTATTCGCAGTGGCTGTGACGTGAACAGTCCCAGACAACCAGGCGCCAATGGAGAAGGAGAGGAAGAGGCTAGA
GATGGGCAGACCCCTTTGCATTTGGCAGCCTCTTGGGGGCTGGAAGAGACAGTACAGTGTCTTCTGGAGTTTGGTGCCAACGTGAACGCA
CAGGATGCAGAAGGAAGAACCCCCATCCACGTGGCCATCAGCAGCCAACACGGTGTCATCATTCAGCTGTTGGTTTCTCACCCCGATATC
CATTTGAATGTACGAGACAGACAAGGGCTGACCCCGTTTGCCTGTGCCATGACTTTCAAGAACAACAAGTCAGCCGAGGCCATTCTCAAA
CGAGAGTCCGGGGCTGCTGAGCAGGTGGATAACAAGGGCCGGAATTTCCTTCATGTGGCAGTTCAGAACTCTGATATTGAAAGTGTGCTG
TTCCTGATCAGTGTCCACGCTAATGTGAATTCAAGAGTCCAGGATGCCTCCAAGTTGACCCCCCTGCACCTCGCTGTCCAAGCAGGCTCA
GAAATTATTGTCCGCAATTTGCTTCTTGCGGGAGCCAAAGTGAACGAATTAACCAAGCATCGCCAGACTGCCCTCCATCTTGCTGCCCAG
CAGGACCTGCCCACCATCTGCTCAGTCCTCCTAGAGAATGGCGTGGACTTTGCTGCCGTGGATGAGAATGGAAACAATGACTTCTGCCTG
GTGTCGAAGGTGGTGGGCAGATGCCGGGCCTCCATGCCTAGGTGGTGGTACAATGTCACTGACGGATCCTGCCAGCTGTTTGTGTATGGG
GGCTGTGACGGAAACAGCAATAATTACCTGACCAAGGAGGAGTGCCTCAAGAAATGTGCCACTGTCACAGAGAATGCCACGGGTGACCTG
GCCACCAGCAGGAATGCAGCGGATTCCTCTGTCCCAAGTGCTCCCAGAAGGCAGGATTCTGAAGACCACTCCAGCGATATGTTCAACTAT
GAAGAATACTGCACCGCCAACGCAGTCACTGGGCCTTGCCGTGCATCCTTCCCACGCTGGTACTTTGACGTGGAGAGGAACTCCTGCAAT
AACTTCATCTATGGAGGCTGCCGGGGCAATAAGAACAGCTACCGCTCTGAGGAGGCCTGCATGCTCCGCTGCTTCCGCCAGCAGGAGAAT
CCTCCCCTGCCCCTTGGCTCAAAGGTGGTGGTTCTGGCGGGGCTGTTCGTGATGGTGTTGATCCTCTTCCTGGGAGCCTCCATGGTCTAC
CTGATCCGGGTGGCACGGAGGAACCAGGAGCGTGCCCTGCGCACCGTCTGGAGCTCCGGAGATGACAAGGAGCAGCTGGTGAAGAACACA
TATGTCCTGTGACCGCCCTGTCGCCAAGAGGACTGGGGAAGGGAGGGGAGACTATGTGTGAGCTTTTTTTAAATAGAGGGATTGACTCGG
ATTTGAGTGATCATTAGGGCTGAGGTCTGTTTCTCTGGGAGGTAGGACGGCTGCTTCCTGGTCTGGCAGGGATGGGTTTGCTTTGGAAAT
CCTCTAGGAGGCTCCTCCTCGCATGGCCTGCAGTCTGGCAGCAGCCCCGAGTTGTTTCCTCGCTGATCGATTTCTTTCCTCCAGGTAGAG
TTTTCTTTGCTTATGTTGAATTCCATTGCCTCTTTTCTCATCACAGAAGTGATGTTGGAATCGTTTCTTTTGTTTGTCTGATTTATGGTT
TTTTTAAGTATAAACAAAAGTTTTTTATTAGCATTCTGAAAGAAGGAAAGTAAAATGTACAAGTTTAATAAAAAGGGGCCTTCCCCTTTA
GAATAAATTTCAGCATGTGCTTTCTTTATGGGAGTCCTAATTTCAACCCTACCAAAATGATCACAAGACACTATCTGAGGTGTCCCATTC

>4432_4432_4_ANKFY1-SPINT2_ANKFY1_chr17_4077204_ENST00000341657_SPINT2_chr19_38774267_ENST00000301244_length(amino acids)=1191AA_BP=974
MAEEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARS
DSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNAS
TLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLES
IATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANP
NMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQHITVSSDQSVNPFEDVPVVNGTSFDENSFAARLIQRGSHT
DAPDTATGNCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADS
VHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAI
QRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPG
PGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVA
ISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSR
VQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNDFCLVSKVVGRCRASM
PRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGP
CRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQERA

--------------------------------------------------------------
>4432_4432_5_ANKFY1-SPINT2_ANKFY1_chr17_4077204_ENST00000570535_SPINT2_chr19_38774267_ENST00000301244_length(transcript)=4427nt_BP=3166nt
GGCCGGGCGTGGTTGCATGGGGGCTCCGCGGGTCTCGCGAGCCTTCCTGTCTAGCCTCTCCGGAGCTTCTCGGGCCGGGGTCCGGAGCGC
GGTTCCTATGACAACGTCCCTCCCGCGATGCCGACCCCGCGGGACTGCGGCCGGCTGCGGAGCCGGGCTGGCAGGTCCCGCGCCGGTGCT
GCGTGCAGCCGCGGGGCCCCGAGGGCAGCACGGGAGGCTCTTGATTGCCGGCGGTGCCGGGACGCCGGGGGAAAGGAGGTGGCCAAGTTG
GAGAAGCACTTGATGCTTCTGCGGCAGGAGTATGTCAAGCTGCAGAAGAAGCTGGCGGAGACAGAGAAGCGCTGCGCTCTCTTGGCTGCG
CAGGCAAACAAGGAGAGCAGCAGCGAGTCCTTCATCAGCCGTCTGCTGGCCATCGTGGCAGACCTCTACGAGCAGGAGCAGTACAGCGAT
CTGAAGATAAAGGTTGGGGACAGGCACATCAGTGCTCACAAGTTTGTCCTGGCAGCCCGCAGTGACAGCTGGAGTCTGGCTAACTTGTCT
TCCACTAAAGAGTTGGACCTGTCAGATGCTAATCCTGAGGTGACGATGACAATGCTTCGCTGGATCTATACAGATGAGCTGGAGTTCAGA
GAGGATGATGTGTTCCTGACTGAACTGATGAAACTAGCAAATCGGTTTCAGCTACAGCTCCTCAGGGAGAGATGTGAGAAGGGTGTTATG
TCTCTAGTGAATGTCAGGAACTGTATTCGCTTCTACCAGACGGCAGAGGAGCTGAATGCCAGCACACTGATGAACTACTGTGCAGAAATT
ATTGCAAGTCATTGGGACGACCTGAGGAAGGAGGATTTCAGCAGCATGAGCGCTCAGTTGTTATACAAAATGATCAAATCCAAGACAGAG
TACCCGCTACATAAAGCCATCAAAGTGGAGAGAGAAGACGTGGTCTTCCTGTATCTGATTGAAATGGATTCCCAGCTCCCTGGGAAGCTG
AATGAAGCGGATCATAACGGAGATCTGGCATTAGATCTAGCCCTCTCACGACGACTGGAGAGTATTGCCACCACGCTGGTTAGTCACAAA
GCTGATGTGGACATGGTGGACAAGAGTGGCTGGAGCTTGTTACACAAAGGAATCCAAAGAGGAGATCTCTTTGCTGCCACTTTCCTCATT
AAGAATGGGGCCTTTGTCAACGCTGCTACACTGGGTGCCCAGGAGACACCACTGCACCTTGTGGCCTTGTACAGTTCAAAGAAACACTCA
GCAGATGTGATGTCTGAGATGGCGCAGATTGCAGAGGCCCTTCTGCAGGCTGGTGCCAACCCCAACATGCAGGACAGCAAGGGGAGGACT
CCTTTACATGTGTCCATCATGGCCGGGAATGAATATGTGTTCAGTCAGCTGCTGCAGTGCAAACAACTAGATTTAGAACTCAAAGACCAC
GAGGGCAGCACGGCTCTGTGGCTGGCAGTGCAGCATATCACAGTGTCTTCTGACCAGTCTGTGAACCCCTTCGAAGATGTCCCCGTGGTA
AATGGGACTTCATTTGATGAGAACAGCTTTGCAGCCAGACTCATCCAGCGCGGCAGCCACACAGACGCACCTGACACGGCGACAGGAAAC
TGTTTACTACAGCGGGCAGCTGGAGCAGGAAACGAGGCAGCAGCTCTTTTCCTGGCAACCAACGGTGCCCATGTCAACCACAGAAACAAG
TGGGGAGAAACCCCGTTGCACACAGCGTGTCGGCATGGCCTGGCCAACCTCACGGCAGAGCTCCTGCAGCAAGGCGCCAACCCAAACCTG
CAGACGGAGGAAGCTCTGCCTCTGCCAAAGGAGGCCGCATCCCTGACCAGCTTGGCGGACAGCGTCCATCTGCAGACGCCACTGCACATG
GCGATCGCCTATAACCATCCGGATGTGGTGTCTGTCATCCTGGAGCAGAAAGCCAATGCTCTTCATGCCACCAACAACTTGCAGATCATT
CCGGACTTCAGCCTCAAAGATTCCCGAGACCAGACTGTGCTGGGCCTGGCATTATGGACTGGCATGCACACGATCGCAGCCCAGCTGCTG
GGCTCTGGAGCCGCCATCAATGACACCATGTCGGATGGGCAGACGCTACTGCACATGGCCATACAGCGGCAGGACAGCAAGAGCGCACTC
TTCCTGCTGGAGCACCAGGCAGATATAAATGTCAGGACTCAGGACGGGGAGACAGCCCTCCAGCTGGCCATCAGAAACCAGCTTCCACTC
GTAGTTGATGCCATATGCACCCGAGGAGCTGACATGTCTGTGCCAGATGAGAAGGGGAACCCCCCGCTGTGGCTTGCATTGGCAAACAAT
CTGGAGGACATCGCATCCACTCTGGTCAGACATGGCTGTGATGCCACATGCTGGGGTCCGGGACCTGGTGGGTGCCTTCAGACGCTCCTG
CACAGAGCCATTGATGAAAACAACGAGCCCACCGCCTGCTTTCTTATTCGCAGTGGCTGTGACGTGAACAGTCCCAGACAACCAGGCGCC
AATGGAGAAGGAGAGGAAGAGGCTAGAGATGGGCAGACCCCTTTGCATTTGGCAGCCTCTTGGGGGCTGGAAGAGACAGTACAGTGTCTT
CTGGAGTTTGGTGCCAACGTGAACGCACAGGATGCAGAAGGAAGAACCCCCATCCACGTGGCCATCAGCAGCCAACACGGTGTCATCATT
CAGCTGTTGGTTTCTCACCCCGATATCCATTTGAATGTACGAGACAGACAAGGGCTGACCCCGTTTGCCTGTGCCATGACTTTCAAGAAC
AACAAGTCAGCCGAGGCCATTCTCAAACGAGAGTCCGGGGCTGCTGAGCAGGTGGATAACAAGGGCCGGAATTTCCTTCATGTGGCAGTT
CAGAACTCTGATATTGAAAGTGTGCTGTTCCTGATCAGTGTCCACGCTAATGTGAATTCAAGAGTCCAGGATGCCTCCAAGTTGACCCCC
CTGCACCTCGCTGTCCAAGCAGGCTCAGAAATTATTGTCCGCAATTTGCTTCTTGCGGGAGCCAAAGTGAACGAATTAACCAAGCATCGC
CAGACTGCCCTCCATCTTGCTGCCCAGCAGGACCTGCCCACCATCTGCTCAGTCCTCCTAGAGAATGGCGTGGACTTTGCTGCCGTGGAT
GAGAATGGAAACAATGACTTCTGCCTGGTGTCGAAGGTGGTGGGCAGATGCCGGGCCTCCATGCCTAGGTGGTGGTACAATGTCACTGAC
GGATCCTGCCAGCTGTTTGTGTATGGGGGCTGTGACGGAAACAGCAATAATTACCTGACCAAGGAGGAGTGCCTCAAGAAATGTGCCACT
GTCACAGAGAATGCCACGGGTGACCTGGCCACCAGCAGGAATGCAGCGGATTCCTCTGTCCCAAGTGCTCCCAGAAGGCAGGATTCTGAA
GACCACTCCAGCGATATGTTCAACTATGAAGAATACTGCACCGCCAACGCAGTCACTGGGCCTTGCCGTGCATCCTTCCCACGCTGGTAC
TTTGACGTGGAGAGGAACTCCTGCAATAACTTCATCTATGGAGGCTGCCGGGGCAATAAGAACAGCTACCGCTCTGAGGAGGCCTGCATG
CTCCGCTGCTTCCGCCAGCAGGAGAATCCTCCCCTGCCCCTTGGCTCAAAGGTGGTGGTTCTGGCGGGGCTGTTCGTGATGGTGTTGATC
CTCTTCCTGGGAGCCTCCATGGTCTACCTGATCCGGGTGGCACGGAGGAACCAGGAGCGTGCCCTGCGCACCGTCTGGAGCTCCGGAGAT
GACAAGGAGCAGCTGGTGAAGAACACATATGTCCTGTGACCGCCCTGTCGCCAAGAGGACTGGGGAAGGGAGGGGAGACTATGTGTGAGC
TTTTTTTAAATAGAGGGATTGACTCGGATTTGAGTGATCATTAGGGCTGAGGTCTGTTTCTCTGGGAGGTAGGACGGCTGCTTCCTGGTC
TGGCAGGGATGGGTTTGCTTTGGAAATCCTCTAGGAGGCTCCTCCTCGCATGGCCTGCAGTCTGGCAGCAGCCCCGAGTTGTTTCCTCGC
TGATCGATTTCTTTCCTCCAGGTAGAGTTTTCTTTGCTTATGTTGAATTCCATTGCCTCTTTTCTCATCACAGAAGTGATGTTGGAATCG
TTTCTTTTGTTTGTCTGATTTATGGTTTTTTTAAGTATAAACAAAAGTTTTTTATTAGCATTCTGAAAGAAGGAAAGTAAAATGTACAAG
TTTAATAAAAAGGGGCCTTCCCCTTTAGAATAAATTTCAGCATGTGCTTTCTTTATGGGAGTCCTAATTTCAACCCTACCAAAATGATCA
CAAGACACTATCTGAGGTGTCCCATTCTAGAAATAGACCCCTCAAAATAGCGTCTTTCAGATCTTTTTGAATGAATCCACAAGATGAAAT

>4432_4432_5_ANKFY1-SPINT2_ANKFY1_chr17_4077204_ENST00000570535_SPINT2_chr19_38774267_ENST00000301244_length(amino acids)=1233AA_BP=1016
MPTPRDCGRLRSRAGRSRAGAACSRGAPRAAREALDCRRCRDAGGKEVAKLEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSE
SFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARSDSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTEL
MKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNASTLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKV
EREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLESIATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAA
TLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANPNMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLA
VQHITVSSDQSVNPFEDVPVVNGTSFDENSFAARLIQRGSHTDAPDTATGNCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTA
CRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADSVHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSR
DQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAIQRQDSKSALFLLEHQADINVRTQDGETALQLAIRNQLPLVVDAICTRG
ADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGPGPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEAR
DGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHVAISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILK
RESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNSRVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQ
QDLPTICSVLLENGVDFAAVDENGNNDFCLVSKVVGRCRASMPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDL
ATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTGPCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQEN

--------------------------------------------------------------
>4432_4432_6_ANKFY1-SPINT2_ANKFY1_chr17_4077204_ENST00000574367_SPINT2_chr19_38774267_ENST00000301244_length(transcript)=4202nt_BP=2941nt
AGTGCCGGGCCAGACATGGCGGAAGAGGAGGTGGCCAAGTTGGAGAAGCACTTGATGCTTCTGCGGCAGGAGTATGTCAAGCTGCAGAAG
AAGCTGGCGGAGACAGAGAAGCGCTGCGCTCTCTTGGCTGCGCAGGCAAACAAGGAGAGCAGCAGCGAGTCCTTCATCAGCCGTCTGCTG
GCCATCGTGGCAGACCTCTACGAGCAGGAGCAGTACAGCGATCTGAAGATAAAGGTTGGGGACAGGCACATCAGTGCTCACAAGTTTGTC
CTGGCAGCCCGCAGTGACAGCTGGAGTCTGGCTAACTTGTCTTCCACTAAAGAGTTGGACCTGTCAGATGCTAATCCTGAGGTGACGATG
ACAATGCTTCGCTGGATCTATACAGATGAGCTGGAGTTCAGAGAGGATGATGTGTTCCTGACTGAACTGATGAAACTAGCAAATCGGTTT
CAGCTACAGCTCCTCAGGGAGAGATGTGAGAAGGGTGTTATGTCTCTAGTGAATGTCAGGAACTGTATTCGCTTCTACCAGACGGCAGAG
GAGCTGAATGCCAGCACACTGATGAACTACTGTGCAGAAATTATTGCAAGTCATTGGGACGACCTGAGGAAGGAGGATTTCAGCAGCATG
AGCGCTCAGTTGTTATACAAAATGATCAAATCCAAGACAGAGTACCCGCTACATAAAGCCATCAAAGTGGAGAGAGAAGACGTGGTCTTC
CTGTATCTGATTGAAATGGATTCCCAGCTCCCTGGGAAGCTGAATGAAGCGGATCATAACGGAGATCTGGCATTAGATCTAGCCCTCTCA
CGACGACTGGAGAGTATTGCCACCACGCTGGTTAGTCACAAAGCTGATGTGGACATGGTGGACAAGAGTGGCTGGAGCTTGTTACACAAA
GGAATCCAAAGAGGAGATCTCTTTGCTGCCACTTTCCTCATTAAGAATGGGGCCTTTGTCAACGCTGCTACACTGGGTGCCCAGGAGACA
CCACTGCACCTTGTGGCCTTGTACAGTTCAAAGAAACACTCAGCAGATGTGATGTCTGAGATGGCGCAGATTGCAGAGGCCCTTCTGCAG
GCTGGTGCCAACCCCAACATGCAGGACAGCAAGGGGAGGACTCCTTTACATGTGTCCATCATGGCCGGGAATGAATATGTGTTCAGTCAG
CTGCTGCAGTGCAAACAACTAGATTTAGAACTCAAAGACCACGAGGGCAGCACGGCTCTGTGGCTGGCAGTGCAGCATATCACAGTGTCT
TCTGACCAGTCTGTGAACCCCTTCGAAGATGTCCCCGTGGTAAATGGGACTTCATTTGATGAGAACAGCTTTGCAGCCAGACTCATCCAG
CGCGGCAGCCACACAGACGCACCTGACACGGCGACAGGAAACTGTTTACTACAGCGGGCAGCTGGAGCAGGAAACGAGGCAGCAGCTCTT
TTCCTGGCAACCAACGGTGCCCATGTCAACCACAGAAACAAGTGGGGAGAAACCCCGTTGCACACAGCGTGTCGGCATGGCCTGGCCAAC
CTCACGGCAGAGCTCCTGCAGCAAGGCGCCAACCCAAACCTGCAGACGGAGGAAGCTCTGCCTCTGCCAAAGGAGGCCGCATCCCTGACC
AGCTTGGCGGACAGCGTCCATCTGCAGACGCCACTGCACATGGCGATCGCCTATAACCATCCGGATGTGGTGTCTGTCATCCTGGAGCAG
AAAGCCAATGCTCTTCATGCCACCAACAACTTGCAGATCATTCCGGACTTCAGCCTCAAAGATTCCCGAGACCAGACTGTGCTGGGCCTG
GCATTATGGACTGGCATGCACACGATCGCAGCCCAGCTGCTGGGCTCTGGAGCCGCCATCAATGACACCATGTCGGATGGGCAGACGCTA
CTGCACATGGCCATACAGCGGCAGGACAGCAAGAGCGCACTCTTCCTGCTGGAGCACCAGGCAGATATAAATGTCAGCAGGACTCAGGAC
GGGGAGACAGCCCTCCAGCTGGCCATCAGAAACCAGCTTCCACTCGTAGTTGATGCCATATGCACCCGAGGAGCTGACATGTCTGTGCCA
GATGAGAAGGGGAACCCCCCGCTGTGGCTTGCATTGGCAAACAATCTGGAGGACATCGCATCCACTCTGGTCAGACATGGCTGTGATGCC
ACATGCTGGGGTCCGGGACCTGGTGGGTGCCTTCAGACGCTCCTGCACAGAGCCATTGATGAAAACAACGAGCCCACCGCCTGCTTTCTT
ATTCGCAGTGGCTGTGACGTGAACAGTCCCAGACAACCAGGCGCCAATGGAGAAGGAGAGGAAGAGGCTAGAGATGGGCAGACCCCTTTG
CATTTGGCAGCCTCTTGGGGGCTGGAAGAGACAGTACAGTGTCTTCTGGAGTTTGGTGCCAACGTGAACGCACAGGATGCAGAAGGAAGA
ACCCCCATCCACGTGGCCATCAGCAGCCAACACGGTGTCATCATTCAGCTGTTGGTTTCTCACCCCGATATCCATTTGAATGTACGAGAC
AGACAAGGGCTGACCCCGTTTGCCTGTGCCATGACTTTCAAGAACAACAAGTCAGCCGAGGCCATTCTCAAACGAGAGTCCGGGGCTGCT
GAGCAGGTGGATAACAAGGGCCGGAATTTCCTTCATGTGGCAGTTCAGAACTCTGATATTGAAAGTGTGCTGTTCCTGATCAGTGTCCAC
GCTAATGTGAATTCAAGAGTCCAGGATGCCTCCAAGTTGACCCCCCTGCACCTCGCTGTCCAAGCAGGCTCAGAAATTATTGTCCGCAAT
TTGCTTCTTGCGGGAGCCAAAGTGAACGAATTAACCAAGCATCGCCAGACTGCCCTCCATCTTGCTGCCCAGCAGGACCTGCCCACCATC
TGCTCAGTCCTCCTAGAGAATGGCGTGGACTTTGCTGCCGTGGATGAGAATGGAAACAATGACTTCTGCCTGGTGTCGAAGGTGGTGGGC
AGATGCCGGGCCTCCATGCCTAGGTGGTGGTACAATGTCACTGACGGATCCTGCCAGCTGTTTGTGTATGGGGGCTGTGACGGAAACAGC
AATAATTACCTGACCAAGGAGGAGTGCCTCAAGAAATGTGCCACTGTCACAGAGAATGCCACGGGTGACCTGGCCACCAGCAGGAATGCA
GCGGATTCCTCTGTCCCAAGTGCTCCCAGAAGGCAGGATTCTGAAGACCACTCCAGCGATATGTTCAACTATGAAGAATACTGCACCGCC
AACGCAGTCACTGGGCCTTGCCGTGCATCCTTCCCACGCTGGTACTTTGACGTGGAGAGGAACTCCTGCAATAACTTCATCTATGGAGGC
TGCCGGGGCAATAAGAACAGCTACCGCTCTGAGGAGGCCTGCATGCTCCGCTGCTTCCGCCAGCAGGAGAATCCTCCCCTGCCCCTTGGC
TCAAAGGTGGTGGTTCTGGCGGGGCTGTTCGTGATGGTGTTGATCCTCTTCCTGGGAGCCTCCATGGTCTACCTGATCCGGGTGGCACGG
AGGAACCAGGAGCGTGCCCTGCGCACCGTCTGGAGCTCCGGAGATGACAAGGAGCAGCTGGTGAAGAACACATATGTCCTGTGACCGCCC
TGTCGCCAAGAGGACTGGGGAAGGGAGGGGAGACTATGTGTGAGCTTTTTTTAAATAGAGGGATTGACTCGGATTTGAGTGATCATTAGG
GCTGAGGTCTGTTTCTCTGGGAGGTAGGACGGCTGCTTCCTGGTCTGGCAGGGATGGGTTTGCTTTGGAAATCCTCTAGGAGGCTCCTCC
TCGCATGGCCTGCAGTCTGGCAGCAGCCCCGAGTTGTTTCCTCGCTGATCGATTTCTTTCCTCCAGGTAGAGTTTTCTTTGCTTATGTTG
AATTCCATTGCCTCTTTTCTCATCACAGAAGTGATGTTGGAATCGTTTCTTTTGTTTGTCTGATTTATGGTTTTTTTAAGTATAAACAAA
AGTTTTTTATTAGCATTCTGAAAGAAGGAAAGTAAAATGTACAAGTTTAATAAAAAGGGGCCTTCCCCTTTAGAATAAATTTCAGCATGT
GCTTTCTTTATGGGAGTCCTAATTTCAACCCTACCAAAATGATCACAAGACACTATCTGAGGTGTCCCATTCTAGAAATAGACCCCTCAA

>4432_4432_6_ANKFY1-SPINT2_ANKFY1_chr17_4077204_ENST00000574367_SPINT2_chr19_38774267_ENST00000301244_length(amino acids)=1192AA_BP=975
MAEEEVAKLEKHLMLLRQEYVKLQKKLAETEKRCALLAAQANKESSSESFISRLLAIVADLYEQEQYSDLKIKVGDRHISAHKFVLAARS
DSWSLANLSSTKELDLSDANPEVTMTMLRWIYTDELEFREDDVFLTELMKLANRFQLQLLRERCEKGVMSLVNVRNCIRFYQTAEELNAS
TLMNYCAEIIASHWDDLRKEDFSSMSAQLLYKMIKSKTEYPLHKAIKVEREDVVFLYLIEMDSQLPGKLNEADHNGDLALDLALSRRLES
IATTLVSHKADVDMVDKSGWSLLHKGIQRGDLFAATFLIKNGAFVNAATLGAQETPLHLVALYSSKKHSADVMSEMAQIAEALLQAGANP
NMQDSKGRTPLHVSIMAGNEYVFSQLLQCKQLDLELKDHEGSTALWLAVQHITVSSDQSVNPFEDVPVVNGTSFDENSFAARLIQRGSHT
DAPDTATGNCLLQRAAGAGNEAAALFLATNGAHVNHRNKWGETPLHTACRHGLANLTAELLQQGANPNLQTEEALPLPKEAASLTSLADS
VHLQTPLHMAIAYNHPDVVSVILEQKANALHATNNLQIIPDFSLKDSRDQTVLGLALWTGMHTIAAQLLGSGAAINDTMSDGQTLLHMAI
QRQDSKSALFLLEHQADINVSRTQDGETALQLAIRNQLPLVVDAICTRGADMSVPDEKGNPPLWLALANNLEDIASTLVRHGCDATCWGP
GPGGCLQTLLHRAIDENNEPTACFLIRSGCDVNSPRQPGANGEGEEEARDGQTPLHLAASWGLEETVQCLLEFGANVNAQDAEGRTPIHV
AISSQHGVIIQLLVSHPDIHLNVRDRQGLTPFACAMTFKNNKSAEAILKRESGAAEQVDNKGRNFLHVAVQNSDIESVLFLISVHANVNS
RVQDASKLTPLHLAVQAGSEIIVRNLLLAGAKVNELTKHRQTALHLAAQQDLPTICSVLLENGVDFAAVDENGNNDFCLVSKVVGRCRAS
MPRWWYNVTDGSCQLFVYGGCDGNSNNYLTKEECLKKCATVTENATGDLATSRNAADSSVPSAPRRQDSEDHSSDMFNYEEYCTANAVTG
PCRASFPRWYFDVERNSCNNFIYGGCRGNKNSYRSEEACMLRCFRQQENPPLPLGSKVVVLAGLFVMVLILFLGASMVYLIRVARRNQER

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ANKFY1-SPINT2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneANKFY1chr17:4077203chr19:38774266ENST00000341657-2025650_759974.33333333333341170.0RHOD and RAB5A
HgeneANKFY1chr17:4077203chr19:38774266ENST00000570535-2025650_7591016.33333333333341212.0RHOD and RAB5A
HgeneANKFY1chr17:4077203chr19:38774266ENST00000574367-2025650_759975.33333333333341171.0RHOD and RAB5A
HgeneANKFY1chr17:4077204chr19:38774267ENST00000341657-2025650_759974.33333333333341170.0RHOD and RAB5A
HgeneANKFY1chr17:4077204chr19:38774267ENST00000570535-2025650_7591016.33333333333341212.0RHOD and RAB5A
HgeneANKFY1chr17:4077204chr19:38774267ENST00000574367-2025650_759975.33333333333341171.0RHOD and RAB5A


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneANKFY1chr17:4077203chr19:38774266ENST00000433651-110650_7590488.0RHOD and RAB5A
HgeneANKFY1chr17:4077204chr19:38774267ENST00000433651-110650_7590488.0RHOD and RAB5A


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANKFY1-SPINT2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANKFY1-SPINT2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource