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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LDLR-ASF1B (FusionGDB2 ID:44402)

Fusion Gene Summary for LDLR-ASF1B

check button Fusion gene summary
Fusion gene informationFusion gene name: LDLR-ASF1B
Fusion gene ID: 44402
HgeneTgene
Gene symbol

LDLR

ASF1B

Gene ID

3949

55723

Gene namelow density lipoprotein receptoranti-silencing function 1B histone chaperone
SynonymsFH|FHC|FHCL1|LDLCQ2CIA-II
Cytomap

19p13.2

19p13.12

Type of geneprotein-codingprotein-coding
Descriptionlow-density lipoprotein receptorLDL receptorlow-density lipoprotein receptor class A domain-containing protein 3histone chaperone ASF1BASF1 anti-silencing function 1 homolog BCCG1-interacting factor A-IIanti-silencing function protein 1 homolog BhAsf1hAsf1bhCIA-II
Modification date2020032220200313
UniProtAcc.

Q9NVP2

Ensembl transtripts involved in fusion geneENST00000455727, ENST00000535915, 
ENST00000545707, ENST00000557933, 
ENST00000558013, ENST00000558518, 
ENST00000560628, 		ENST00000263382, 
ENST00000474890, ENST00000592798, 
Fusion gene scores* DoF score23 X 17 X 15=58657 X 5 X 6=210
# samples 338
** MAII scorelog2(33/5865*10)=-4.15159317867005
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(8/210*10)=-1.39231742277876
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LDLR [Title/Abstract] AND ASF1B [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLDLR(11218190)-ASF1B(14237049), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneASF1B

GO:0006335

DNA replication-dependent nucleosome assembly

14718166

TgeneASF1B

GO:0006336

DNA replication-independent nucleosome assembly

14718166


check buttonFusion gene breakpoints across LDLR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ASF1B (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-HU-A4GPLDLRchr19

11218190

+ASF1Bchr19

14237049

-


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Fusion Gene ORF analysis for LDLR-ASF1B

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000455727ENST00000263382LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000455727ENST00000474890LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000455727ENST00000592798LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000535915ENST00000263382LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000535915ENST00000474890LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000535915ENST00000592798LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000545707ENST00000263382LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000545707ENST00000474890LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000545707ENST00000592798LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000557933ENST00000263382LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000557933ENST00000474890LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000557933ENST00000592798LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000558013ENST00000263382LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000558013ENST00000474890LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000558013ENST00000592798LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000558518ENST00000263382LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000558518ENST00000474890LDLRchr19

11218190

+ASF1Bchr19

14237049

-
In-frameENST00000558518ENST00000592798LDLRchr19

11218190

+ASF1Bchr19

14237049

-
intron-3CDSENST00000560628ENST00000263382LDLRchr19

11218190

+ASF1Bchr19

14237049

-
intron-3CDSENST00000560628ENST00000474890LDLRchr19

11218190

+ASF1Bchr19

14237049

-
intron-3CDSENST00000560628ENST00000592798LDLRchr19

11218190

+ASF1Bchr19

14237049

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000558518LDLRchr1911218190+ENST00000263382ASF1Bchr1914237049-257711271691626485
ENST00000558518LDLRchr1911218190+ENST00000592798ASF1Bchr1914237049-169011271691449426
ENST00000558518LDLRchr1911218190+ENST00000474890ASF1Bchr1914237049-166511271691515448
ENST00000557933LDLRchr1911218190+ENST00000263382ASF1Bchr1914237049-24771027691526485
ENST00000557933LDLRchr1911218190+ENST00000592798ASF1Bchr1914237049-15901027691349426
ENST00000557933LDLRchr1911218190+ENST00000474890ASF1Bchr1914237049-15651027691415448
ENST00000455727LDLRchr1911218190+ENST00000263382ASF1Bchr1914237049-1972522681021317
ENST00000455727LDLRchr1911218190+ENST00000592798ASF1Bchr1914237049-108552268844258
ENST00000455727LDLRchr1911218190+ENST00000474890ASF1Bchr1914237049-106052268910280
ENST00000535915LDLRchr1911218190+ENST00000263382ASF1Bchr1914237049-2353903681402444
ENST00000535915LDLRchr1911218190+ENST00000592798ASF1Bchr1914237049-1466903681225385
ENST00000535915LDLRchr1911218190+ENST00000474890ASF1Bchr1914237049-1441903681291407
ENST00000545707LDLRchr1911218190+ENST00000263382ASF1Bchr1914237049-2095645681144358
ENST00000545707LDLRchr1911218190+ENST00000592798ASF1Bchr1914237049-120864568967299
ENST00000545707LDLRchr1911218190+ENST00000474890ASF1Bchr1914237049-1183645681033321
ENST00000558013LDLRchr1911218190+ENST00000263382ASF1Bchr1914237049-24611011531510485
ENST00000558013LDLRchr1911218190+ENST00000592798ASF1Bchr1914237049-15741011531333426
ENST00000558013LDLRchr1911218190+ENST00000474890ASF1Bchr1914237049-15491011531399448

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000558518ENST00000263382LDLRchr1911218190+ASF1Bchr1914237049-0.0090183270.99098164
ENST00000558518ENST00000592798LDLRchr1911218190+ASF1Bchr1914237049-0.0188154190.98118454
ENST00000558518ENST00000474890LDLRchr1911218190+ASF1Bchr1914237049-0.0105063720.9894936
ENST00000557933ENST00000263382LDLRchr1911218190+ASF1Bchr1914237049-0.0089965820.9910034
ENST00000557933ENST00000592798LDLRchr1911218190+ASF1Bchr1914237049-0.0192813150.98071873
ENST00000557933ENST00000474890LDLRchr1911218190+ASF1Bchr1914237049-0.0107280350.989272
ENST00000455727ENST00000263382LDLRchr1911218190+ASF1Bchr1914237049-0.0085509980.99144894
ENST00000455727ENST00000592798LDLRchr1911218190+ASF1Bchr1914237049-0.0167782590.98322177
ENST00000455727ENST00000474890LDLRchr1911218190+ASF1Bchr1914237049-0.0145658080.9854342
ENST00000535915ENST00000263382LDLRchr1911218190+ASF1Bchr1914237049-0.0066445140.9933555
ENST00000535915ENST00000592798LDLRchr1911218190+ASF1Bchr1914237049-0.0153559880.98464406
ENST00000535915ENST00000474890LDLRchr1911218190+ASF1Bchr1914237049-0.007186340.99281365
ENST00000545707ENST00000263382LDLRchr1911218190+ASF1Bchr1914237049-0.0046230670.99537694
ENST00000545707ENST00000592798LDLRchr1911218190+ASF1Bchr1914237049-0.0128776940.98712236
ENST00000545707ENST00000474890LDLRchr1911218190+ASF1Bchr1914237049-0.0052348970.99476504
ENST00000558013ENST00000263382LDLRchr1911218190+ASF1Bchr1914237049-0.0088389260.991161
ENST00000558013ENST00000592798LDLRchr1911218190+ASF1Bchr1914237049-0.018959350.98104066
ENST00000558013ENST00000474890LDLRchr1911218190+ASF1Bchr1914237049-0.0107625060.9892374

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Fusion Genomic Features for LDLR-ASF1B


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LDLR-ASF1B


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:11218190/chr19:14237049)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ASF1B

Q9NVP2

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly. Does not participate in replication-independent nucleosome deposition which is mediated by ASF1A and HIRA. Required for spermatogenesis. {ECO:0000269|PubMed:11897662, ECO:0000269|PubMed:12842904, ECO:0000269|PubMed:14718166, ECO:0000269|PubMed:15664198, ECO:0000269|PubMed:16151251}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416107_145145693.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+41625_65145693.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+41666_106145693.0DomainLDL-receptor class A 2
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517107_145272820.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517146_186272820.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517195_233272820.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517234_272272820.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+51725_65272820.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+51766_106272820.0DomainLDL-receptor class A 2
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516107_145186683.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516146_186186683.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+51625_65186683.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+51666_106186683.0DomainLDL-receptor class A 2
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618107_145313859.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618146_186313859.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618195_233313859.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618234_272313859.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+61825_65313859.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618274_313313859.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+61866_106313859.0DomainLDL-receptor class A 2
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618107_145313861.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618146_186313861.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618195_233313861.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618234_272313861.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+61825_65313861.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618274_313313861.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+61866_106313861.0DomainLDL-receptor class A 2

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416146_186145693.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416195_233145693.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416234_272145693.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416274_313145693.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416314_353145693.0DomainEGF-like 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416354_393145693.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416663_712145693.0DomainEGF-like 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517274_313272820.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517314_353272820.0DomainEGF-like 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517354_393272820.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517663_712272820.0DomainEGF-like 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516195_233186683.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516234_272186683.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516274_313186683.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516314_353186683.0DomainEGF-like 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516354_393186683.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516663_712186683.0DomainEGF-like 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618314_353313859.0DomainEGF-like 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618354_393313859.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618663_712313859.0DomainEGF-like 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618314_353313861.0DomainEGF-like 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618354_393313861.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618663_712313861.0DomainEGF-like 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416823_828145693.0MotifNPXY motif
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517823_828272820.0MotifNPXY motif
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516823_828186683.0MotifNPXY motif
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618823_828313859.0MotifNPXY motif
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618823_828313861.0MotifNPXY motif
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416721_768145693.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416811_860145693.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517721_768272820.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517811_860272820.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516721_768186683.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516811_860186683.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618721_768313859.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618811_860313859.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618721_768313861.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618811_860313861.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416397_438145693.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416439_485145693.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416486_528145693.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416529_572145693.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416573_615145693.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416616_658145693.0RepeatNote=LDL-receptor class B 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517397_438272820.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517439_485272820.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517486_528272820.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517529_572272820.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517573_615272820.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517616_658272820.0RepeatNote=LDL-receptor class B 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516397_438186683.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516439_485186683.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516486_528186683.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516529_572186683.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516573_615186683.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516616_658186683.0RepeatNote=LDL-receptor class B 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618397_438313859.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618439_485313859.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618486_528313859.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618529_572313859.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618573_615313859.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618616_658313859.0RepeatNote=LDL-receptor class B 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618397_438313861.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618439_485313861.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618486_528313861.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618529_572313861.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618573_615313861.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618616_658313861.0RepeatNote=LDL-receptor class B 6
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+41622_788145693.0Topological domainExtracellular
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+51722_788272820.0Topological domainExtracellular
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+51622_788186683.0Topological domainExtracellular
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+61822_788313859.0Topological domainExtracellular
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+61822_788313861.0Topological domainExtracellular
HgeneLDLRchr19:11218190chr19:14237049ENST00000455727+416789_810145693.0TransmembraneHelical
HgeneLDLRchr19:11218190chr19:14237049ENST00000535915+517789_810272820.0TransmembraneHelical
HgeneLDLRchr19:11218190chr19:14237049ENST00000545707+516789_810186683.0TransmembraneHelical
HgeneLDLRchr19:11218190chr19:14237049ENST00000558013+618789_810313859.0TransmembraneHelical
HgeneLDLRchr19:11218190chr19:14237049ENST00000558518+618789_810313861.0TransmembraneHelical


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Fusion Gene Sequence for LDLR-ASF1B


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>44402_44402_1_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000455727_ASF1B_chr19_14237049_ENST00000263382_length(transcript)=1972nt_BP=522nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCA
TCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCA
TTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTG
TCTTTCAGGCCGACGCCCCCAACCCATCCCTCATCCCAGAGACTGATGCCGTGGGTGTGACTGTGGTCCTCATCACCTGCACCTACCATG
GACAGGAGTTCATCCGAGTGGGCTACTACGTCAACAACGAGTACCTCAACCCTGAGCTGCGTGAGAACCCGCCCATGAAGCCAGATTTCT
CCCAGCTCCAGCGGAACATCTTGGCCTCGAACCCCCGGGTGACCCGCTTCCATATCAACTGGGACAACAACATGGACAGGCTGGAGGCCA
TAGAGACCCAGGACCCCTCCCTGGGCTGCGGCCTCCCACTCAACTGCACTCCTATCAAGGGCTTGGGGCTCCCTGGCTGCATCCCTGGCC
TCCTCCCTGAGAACTCCATGGACTGCATCTAACTGCAGGAACCCAGAGTGTCCCAGCACGCCGGGAGGGGCAACCAGGCCTCCCAGCGAG
TCCTGCAGGGCCCATCTAGAGGACTTTGGGGGCCATCAGCTGCAATCCAGGTCTGTCAAACTCAGCCCCTAGGAAAGAACAGGCCTTGGG
TCTCCCCTAGTCCTGGCCAGAAGGATGATCTCGCTTTTCCTCTACAGGCCTATAAGAAGCAGGTACTTCAGTTCTAAATTCTGACTTGTG
TTCTTTTCGTCTTCATAAATTCTAACTAAGGCCACTGTGCCACTGTGCACCCTTGAGTACCATTGATCCAAAGCTTTCCCACAGACCTCC
CTGGCCCACCTAGAGGCTTTCTTGGTCAGTGCCTGTCAAGGCTCCAGTCCTGCTGAGCCAAAGGCTTTGTCATTCCTTTCTCTTCCTGTA
CATCTGAGCAGACCCACTCCAGCTTTCTGGTGTCACAGGCGGGAATGTTAGTTAGTAGGTAGACTTAGATCCCATTTCTGTCCTGCTCCC
AGGAAGATTCTTAGGTCCTCTTCAATCCAGCAGCCCCTCCCAGAGGTGTGATCAGCAGGATGCTGAGGAACCATGTTGCCTTTCCTGTCA
ATCACAGCCACCTTCCTGTTATCTCCTAAATGGATCTGGCTTTTCCTGGAGGCTGCCATGGTTGGAAGATGGTATCAGAGGGCCTGCCTG
GGCAGTCTGTCTCCGGGCCAGGGTCAGGGACCCTCTGCCTCTGGCAGCCTTAACCTGTCCTCTGCTAGGACCAGGGTGATTTCAAGCCAG
GGAAGCAACTGGGACCCTGAAAACTGTCCCTCCCCAGCCCGCTCCCCCTCTCTGTGCCCTGGTCCCCTTGCTGCCATGTGGATGCTGTTG

>44402_44402_1_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000455727_ASF1B_chr19_14237049_ENST00000263382_length(amino acids)=317AA_BP=151
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCLTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPV
PAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYLNPELRENPPMKPDFSQLQRNILASNPRVTRFHINWDN

--------------------------------------------------------------
>44402_44402_2_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000455727_ASF1B_chr19_14237049_ENST00000474890_length(transcript)=1060nt_BP=522nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCA
TCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCA
TTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTG
TCTTTCAGGCCGACGCCCCCAACCCATCCCTCATCCCAGAGACTGATGCCGTGGGTGTGACTGTGGTCCTCATCACCTGCACCTACCATG
GACAGGAGTTCATCCGAGTGGGCTACTACGTCAACAACGAGTACCTCAACCCTGAGCTGCGTGAGAACCCGCCCATGAAGCCAGATTTCT
CCCAGGTGGGGCCTGTTTCCACTTCCTGCTTCCCACAAGGCCGTTCTTTATACTTGGGGGGAGTTCAGCCATTCAAATTGAGAGTCAAGG
TCACTTCTTAAGGTTTTCAAGTAATATTCAGTTCTTACAGTACTGTGTTAGAAGAGGAGAAAAAGACCTTTGTCTCTCAAAGGCATGTCT

>44402_44402_2_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000455727_ASF1B_chr19_14237049_ENST00000474890_length(amino acids)=280AA_BP=151
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCLTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPV
PAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYLNPELRENPPMKPDFSQVGPVSTSCFPQGRSLYLGGVQ

--------------------------------------------------------------
>44402_44402_3_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000455727_ASF1B_chr19_14237049_ENST00000592798_length(transcript)=1085nt_BP=522nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCA
TCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCA
TTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTG
TCTTTCAGCTCCAGCGGAACATCTTGGCCTCGAACCCCCGGGTGACCCGCTTCCATATCAACTGGGACAACAACATGGACAGGCTGGAGG
CCATAGAGACCCAGGACCCCTCCCTGGGCTGCGGCCTCCCACTCAACTGCACTCCTATCAAGGGCTTGGGGCTCCCTGGCTGCATCCCTG
GCCTCCTCCCTGAGAACTCCATGGACTGCATCTAACTGCAGGAACCCAGAGTGTCCCAGCACGCCGGGAGGGGCAACCAGGCCTCCCAGC
GAGTCCTGCAGGGCCCATCTAGAGGACTTTGGGGGCCATCAGCTGCAATCCAGGTCTGTCAAACTCAGCCCCTAGGAAAGAACAGGCCTT
GGGTCTCCCCTAGTCCTGGCCAGAAGGATGATCTCGCTTTTCCTCTACAGGCCTATAAGAAGCAGGTACTTCAGTTCTAAATTCTGACTT

>44402_44402_3_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000455727_ASF1B_chr19_14237049_ENST00000592798_length(amino acids)=258AA_BP=151
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCLTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPV

--------------------------------------------------------------
>44402_44402_4_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000535915_ASF1B_chr19_14237049_ENST00000263382_length(transcript)=2353nt_BP=903nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGG
ACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCC
AGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGG
ACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCA
AGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCC
GGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCA
AGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGT
GCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGC
CAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCCATCCCTCATCCCAGAGACTGATGCCGTGGGTGTGACTGTGGTCC
TCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTACTACGTCAACAACGAGTACCTCAACCCTGAGCTGCGTGAGAACC
CGCCCATGAAGCCAGATTTCTCCCAGCTCCAGCGGAACATCTTGGCCTCGAACCCCCGGGTGACCCGCTTCCATATCAACTGGGACAACA
ACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCTGGGCTGCGGCCTCCCACTCAACTGCACTCCTATCAAGGGCTTGGGGC
TCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGACTGCATCTAACTGCAGGAACCCAGAGTGTCCCAGCACGCCGGGAGGG
GCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGGACTTTGGGGGCCATCAGCTGCAATCCAGGTCTGTCAAACTCAGCCCC
TAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAAGGATGATCTCGCTTTTCCTCTACAGGCCTATAAGAAGCAGGTACTTC
AGTTCTAAATTCTGACTTGTGTTCTTTTCGTCTTCATAAATTCTAACTAAGGCCACTGTGCCACTGTGCACCCTTGAGTACCATTGATCC
AAAGCTTTCCCACAGACCTCCCTGGCCCACCTAGAGGCTTTCTTGGTCAGTGCCTGTCAAGGCTCCAGTCCTGCTGAGCCAAAGGCTTTG
TCATTCCTTTCTCTTCCTGTACATCTGAGCAGACCCACTCCAGCTTTCTGGTGTCACAGGCGGGAATGTTAGTTAGTAGGTAGACTTAGA
TCCCATTTCTGTCCTGCTCCCAGGAAGATTCTTAGGTCCTCTTCAATCCAGCAGCCCCTCCCAGAGGTGTGATCAGCAGGATGCTGAGGA
ACCATGTTGCCTTTCCTGTCAATCACAGCCACCTTCCTGTTATCTCCTAAATGGATCTGGCTTTTCCTGGAGGCTGCCATGGTTGGAAGA
TGGTATCAGAGGGCCTGCCTGGGCAGTCTGTCTCCGGGCCAGGGTCAGGGACCCTCTGCCTCTGGCAGCCTTAACCTGTCCTCTGCTAGG
ACCAGGGTGATTTCAAGCCAGGGAAGCAACTGGGACCCTGAAAACTGTCCCTCCCCAGCCCGCTCCCCCTCTCTGTGCCCTGGTCCCCTT
GCTGCCATGTGGATGCTGTTGTGATTGCTGTTTGTATATTATCAAAATGTTTTTATATTAAAAATGTTTGGTCTGAAAATTAAAAGCACT

>44402_44402_4_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000535915_ASF1B_chr19_14237049_ENST00000263382_length(amino acids)=444AA_BP=278
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGKCISRQ
FVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWR
CDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW
SDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYL

--------------------------------------------------------------
>44402_44402_5_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000535915_ASF1B_chr19_14237049_ENST00000474890_length(transcript)=1441nt_BP=903nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGG
ACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCC
AGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGG
ACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCA
AGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCC
GGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCA
AGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGT
GCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGC
CAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCCATCCCTCATCCCAGAGACTGATGCCGTGGGTGTGACTGTGGTCC
TCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTACTACGTCAACAACGAGTACCTCAACCCTGAGCTGCGTGAGAACC
CGCCCATGAAGCCAGATTTCTCCCAGGTGGGGCCTGTTTCCACTTCCTGCTTCCCACAAGGCCGTTCTTTATACTTGGGGGGAGTTCAGC
CATTCAAATTGAGAGTCAAGGTCACTTCTTAAGGTTTTCAAGTAATATTCAGTTCTTACAGTACTGTGTTAGAAGAGGAGAAAAAGACCT
TTGTCTCTCAAAGGCATGTCTTAGAGAATTAAGATTAGGCCAGCCTGGGCAACATAGTGAGACCCTGTCCCTAACCCCCGCAAAAAAAAA

>44402_44402_5_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000535915_ASF1B_chr19_14237049_ENST00000474890_length(amino acids)=407AA_BP=278
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGKCISRQ
FVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWR
CDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW
SDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYL

--------------------------------------------------------------
>44402_44402_6_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000535915_ASF1B_chr19_14237049_ENST00000592798_length(transcript)=1466nt_BP=903nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGG
ACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCC
AGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGG
ACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCA
AGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCC
GGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCA
AGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGT
GCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGC
CAGCAGGGAGACACATGTTTGTCTTTCAGCTCCAGCGGAACATCTTGGCCTCGAACCCCCGGGTGACCCGCTTCCATATCAACTGGGACA
ACAACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCTGGGCTGCGGCCTCCCACTCAACTGCACTCCTATCAAGGGCTTGG
GGCTCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGACTGCATCTAACTGCAGGAACCCAGAGTGTCCCAGCACGCCGGGA
GGGGCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGGACTTTGGGGGCCATCAGCTGCAATCCAGGTCTGTCAAACTCAGC
CCCTAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAAGGATGATCTCGCTTTTCCTCTACAGGCCTATAAGAAGCAGGTAC

>44402_44402_6_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000535915_ASF1B_chr19_14237049_ENST00000592798_length(amino acids)=385AA_BP=278
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGKCISRQ
FVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWR
CDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW
SDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQLQRNILASNPRVTRFHINWDNNMDRLEAIETQDPSLGCGLPLN

--------------------------------------------------------------
>44402_44402_7_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000545707_ASF1B_chr19_14237049_ENST00000263382_length(transcript)=2095nt_BP=645nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCA
TCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGAC
CCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAAC
CCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGGTGCTGG
TGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCCATCCCTCATCCCAGAGACTGATGCCGTGGGTG
TGACTGTGGTCCTCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTACTACGTCAACAACGAGTACCTCAACCCTGAGC
TGCGTGAGAACCCGCCCATGAAGCCAGATTTCTCCCAGCTCCAGCGGAACATCTTGGCCTCGAACCCCCGGGTGACCCGCTTCCATATCA
ACTGGGACAACAACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCTGGGCTGCGGCCTCCCACTCAACTGCACTCCTATCA
AGGGCTTGGGGCTCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGACTGCATCTAACTGCAGGAACCCAGAGTGTCCCAGC
ACGCCGGGAGGGGCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGGACTTTGGGGGCCATCAGCTGCAATCCAGGTCTGTC
AAACTCAGCCCCTAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAAGGATGATCTCGCTTTTCCTCTACAGGCCTATAAGA
AGCAGGTACTTCAGTTCTAAATTCTGACTTGTGTTCTTTTCGTCTTCATAAATTCTAACTAAGGCCACTGTGCCACTGTGCACCCTTGAG
TACCATTGATCCAAAGCTTTCCCACAGACCTCCCTGGCCCACCTAGAGGCTTTCTTGGTCAGTGCCTGTCAAGGCTCCAGTCCTGCTGAG
CCAAAGGCTTTGTCATTCCTTTCTCTTCCTGTACATCTGAGCAGACCCACTCCAGCTTTCTGGTGTCACAGGCGGGAATGTTAGTTAGTA
GGTAGACTTAGATCCCATTTCTGTCCTGCTCCCAGGAAGATTCTTAGGTCCTCTTCAATCCAGCAGCCCCTCCCAGAGGTGTGATCAGCA
GGATGCTGAGGAACCATGTTGCCTTTCCTGTCAATCACAGCCACCTTCCTGTTATCTCCTAAATGGATCTGGCTTTTCCTGGAGGCTGCC
ATGGTTGGAAGATGGTATCAGAGGGCCTGCCTGGGCAGTCTGTCTCCGGGCCAGGGTCAGGGACCCTCTGCCTCTGGCAGCCTTAACCTG
TCCTCTGCTAGGACCAGGGTGATTTCAAGCCAGGGAAGCAACTGGGACCCTGAAAACTGTCCCTCCCCAGCCCGCTCCCCCTCTCTGTGC
CCTGGTCCCCTTGCTGCCATGTGGATGCTGTTGTGATTGCTGTTTGTATATTATCAAAATGTTTTTATATTAAAAATGTTTGGTCTGAAA

>44402_44402_7_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000545707_ASF1B_chr19_14237049_ENST00000263382_length(amino acids)=358AA_BP=192
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARD
CRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVN

--------------------------------------------------------------
>44402_44402_8_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000545707_ASF1B_chr19_14237049_ENST00000474890_length(transcript)=1183nt_BP=645nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCA
TCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGAC
CCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAAC
CCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGGTGCTGG
TGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCCATCCCTCATCCCAGAGACTGATGCCGTGGGTG
TGACTGTGGTCCTCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTACTACGTCAACAACGAGTACCTCAACCCTGAGC
TGCGTGAGAACCCGCCCATGAAGCCAGATTTCTCCCAGGTGGGGCCTGTTTCCACTTCCTGCTTCCCACAAGGCCGTTCTTTATACTTGG
GGGGAGTTCAGCCATTCAAATTGAGAGTCAAGGTCACTTCTTAAGGTTTTCAAGTAATATTCAGTTCTTACAGTACTGTGTTAGAAGAGG
AGAAAAAGACCTTTGTCTCTCAAAGGCATGTCTTAGAGAATTAAGATTAGGCCAGCCTGGGCAACATAGTGAGACCCTGTCCCTAACCCC

>44402_44402_8_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000545707_ASF1B_chr19_14237049_ENST00000474890_length(amino acids)=321AA_BP=192
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARD
CRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQADAPNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVN

--------------------------------------------------------------
>44402_44402_9_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000545707_ASF1B_chr19_14237049_ENST00000592798_length(transcript)=1208nt_BP=645nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCA
TCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGAC
CCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAAC
CCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGGTGCTGG
TGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGCTCCAGCGGAACATCTTGGCCTCGAACCCCCGGGTGACCCGCTTCCATA
TCAACTGGGACAACAACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCTGGGCTGCGGCCTCCCACTCAACTGCACTCCTA
TCAAGGGCTTGGGGCTCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGACTGCATCTAACTGCAGGAACCCAGAGTGTCCC
AGCACGCCGGGAGGGGCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGGACTTTGGGGGCCATCAGCTGCAATCCAGGTCT
GTCAAACTCAGCCCCTAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAAGGATGATCTCGCTTTTCCTCTACAGGCCTATA

>44402_44402_9_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000545707_ASF1B_chr19_14237049_ENST00000592798_length(amino acids)=299AA_BP=192
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARD
CRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQLQRNILASNPRVTRFHINWDNNMDRLEAIETQDPSLGCG

--------------------------------------------------------------
>44402_44402_10_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000557933_ASF1B_chr19_14237049_ENST00000263382_length(transcript)=2477nt_BP=1027nt
AGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATG
GGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAG
TTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAG
ACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGC
CAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGC
ATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCC
AGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCG
CAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCAC
TCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTC
CAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTT
AATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGAC
TGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGAT
CAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCCATCCCTCATC
CCAGAGACTGATGCCGTGGGTGTGACTGTGGTCCTCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTACTACGTCAAC
AACGAGTACCTCAACCCTGAGCTGCGTGAGAACCCGCCCATGAAGCCAGATTTCTCCCAGCTCCAGCGGAACATCTTGGCCTCGAACCCC
CGGGTGACCCGCTTCCATATCAACTGGGACAACAACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCTGGGCTGCGGCCTC
CCACTCAACTGCACTCCTATCAAGGGCTTGGGGCTCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGACTGCATCTAACTG
CAGGAACCCAGAGTGTCCCAGCACGCCGGGAGGGGCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGGACTTTGGGGGCCA
TCAGCTGCAATCCAGGTCTGTCAAACTCAGCCCCTAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAAGGATGATCTCGCT
TTTCCTCTACAGGCCTATAAGAAGCAGGTACTTCAGTTCTAAATTCTGACTTGTGTTCTTTTCGTCTTCATAAATTCTAACTAAGGCCAC
TGTGCCACTGTGCACCCTTGAGTACCATTGATCCAAAGCTTTCCCACAGACCTCCCTGGCCCACCTAGAGGCTTTCTTGGTCAGTGCCTG
TCAAGGCTCCAGTCCTGCTGAGCCAAAGGCTTTGTCATTCCTTTCTCTTCCTGTACATCTGAGCAGACCCACTCCAGCTTTCTGGTGTCA
CAGGCGGGAATGTTAGTTAGTAGGTAGACTTAGATCCCATTTCTGTCCTGCTCCCAGGAAGATTCTTAGGTCCTCTTCAATCCAGCAGCC
CCTCCCAGAGGTGTGATCAGCAGGATGCTGAGGAACCATGTTGCCTTTCCTGTCAATCACAGCCACCTTCCTGTTATCTCCTAAATGGAT
CTGGCTTTTCCTGGAGGCTGCCATGGTTGGAAGATGGTATCAGAGGGCCTGCCTGGGCAGTCTGTCTCCGGGCCAGGGTCAGGGACCCTC
TGCCTCTGGCAGCCTTAACCTGTCCTCTGCTAGGACCAGGGTGATTTCAAGCCAGGGAAGCAACTGGGACCCTGAAAACTGTCCCTCCCC
AGCCCGCTCCCCCTCTCTGTGCCCTGGTCCCCTTGCTGCCATGTGGATGCTGTTGTGATTGCTGTTTGTATATTATCAAAATGTTTTTAT

>44402_44402_10_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000557933_ASF1B_chr19_14237049_ENST00000263382_length(amino acids)=485AA_BP=319
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQAD
APNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYLNPELRENPPMKPDFSQLQRNILASNPRVTRFHINWDNNMDRLEAIETQD

--------------------------------------------------------------
>44402_44402_11_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000557933_ASF1B_chr19_14237049_ENST00000474890_length(transcript)=1565nt_BP=1027nt
AGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATG
GGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAG
TTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAG
ACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGC
CAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGC
ATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCC
AGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCG
CAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCAC
TCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTC
CAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTT
AATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGAC
TGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGAT
CAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCCATCCCTCATC
CCAGAGACTGATGCCGTGGGTGTGACTGTGGTCCTCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTACTACGTCAAC
AACGAGTACCTCAACCCTGAGCTGCGTGAGAACCCGCCCATGAAGCCAGATTTCTCCCAGGTGGGGCCTGTTTCCACTTCCTGCTTCCCA
CAAGGCCGTTCTTTATACTTGGGGGGAGTTCAGCCATTCAAATTGAGAGTCAAGGTCACTTCTTAAGGTTTTCAAGTAATATTCAGTTCT
TACAGTACTGTGTTAGAAGAGGAGAAAAAGACCTTTGTCTCTCAAAGGCATGTCTTAGAGAATTAAGATTAGGCCAGCCTGGGCAACATA

>44402_44402_11_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000557933_ASF1B_chr19_14237049_ENST00000474890_length(amino acids)=448AA_BP=319
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQAD

--------------------------------------------------------------
>44402_44402_12_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000557933_ASF1B_chr19_14237049_ENST00000592798_length(transcript)=1590nt_BP=1027nt
AGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATG
GGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAG
TTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAG
ACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGC
CAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGC
ATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCC
AGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCG
CAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCAC
TCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTC
CAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTT
AATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGAC
TGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGAT
CAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGCTCCAGCGGAACATCTTGGCCTCGAAC
CCCCGGGTGACCCGCTTCCATATCAACTGGGACAACAACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCTGGGCTGCGGC
CTCCCACTCAACTGCACTCCTATCAAGGGCTTGGGGCTCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGACTGCATCTAA
CTGCAGGAACCCAGAGTGTCCCAGCACGCCGGGAGGGGCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGGACTTTGGGGG
CCATCAGCTGCAATCCAGGTCTGTCAAACTCAGCCCCTAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAAGGATGATCTC

>44402_44402_12_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000557933_ASF1B_chr19_14237049_ENST00000592798_length(amino acids)=426AA_BP=319
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQLQ

--------------------------------------------------------------
>44402_44402_13_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558013_ASF1B_chr19_14237049_ENST00000263382_length(transcript)=2461nt_BP=1011nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGTTCCAGTGCCAAGACG
GGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGACGTGCTTGTCTGTCA
CCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCCAAGTGGACTGCGACA
ACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCG
TCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACA
GCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTC
TTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTG
ATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAA
ACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCG
AGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAG
ATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGG
TGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCCATCCCTCATCCCAGAGACTGATGCCG
TGGGTGTGACTGTGGTCCTCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTACTACGTCAACAACGAGTACCTCAACC
CTGAGCTGCGTGAGAACCCGCCCATGAAGCCAGATTTCTCCCAGCTCCAGCGGAACATCTTGGCCTCGAACCCCCGGGTGACCCGCTTCC
ATATCAACTGGGACAACAACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCTGGGCTGCGGCCTCCCACTCAACTGCACTC
CTATCAAGGGCTTGGGGCTCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGACTGCATCTAACTGCAGGAACCCAGAGTGT
CCCAGCACGCCGGGAGGGGCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGGACTTTGGGGGCCATCAGCTGCAATCCAGG
TCTGTCAAACTCAGCCCCTAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAAGGATGATCTCGCTTTTCCTCTACAGGCCT
ATAAGAAGCAGGTACTTCAGTTCTAAATTCTGACTTGTGTTCTTTTCGTCTTCATAAATTCTAACTAAGGCCACTGTGCCACTGTGCACC
CTTGAGTACCATTGATCCAAAGCTTTCCCACAGACCTCCCTGGCCCACCTAGAGGCTTTCTTGGTCAGTGCCTGTCAAGGCTCCAGTCCT
GCTGAGCCAAAGGCTTTGTCATTCCTTTCTCTTCCTGTACATCTGAGCAGACCCACTCCAGCTTTCTGGTGTCACAGGCGGGAATGTTAG
TTAGTAGGTAGACTTAGATCCCATTTCTGTCCTGCTCCCAGGAAGATTCTTAGGTCCTCTTCAATCCAGCAGCCCCTCCCAGAGGTGTGA
TCAGCAGGATGCTGAGGAACCATGTTGCCTTTCCTGTCAATCACAGCCACCTTCCTGTTATCTCCTAAATGGATCTGGCTTTTCCTGGAG
GCTGCCATGGTTGGAAGATGGTATCAGAGGGCCTGCCTGGGCAGTCTGTCTCCGGGCCAGGGTCAGGGACCCTCTGCCTCTGGCAGCCTT
AACCTGTCCTCTGCTAGGACCAGGGTGATTTCAAGCCAGGGAAGCAACTGGGACCCTGAAAACTGTCCCTCCCCAGCCCGCTCCCCCTCT
CTGTGCCCTGGTCCCCTTGCTGCCATGTGGATGCTGTTGTGATTGCTGTTTGTATATTATCAAAATGTTTTTATATTAAAAATGTTTGGT

>44402_44402_13_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558013_ASF1B_chr19_14237049_ENST00000263382_length(amino acids)=485AA_BP=319
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQAD
APNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYLNPELRENPPMKPDFSQLQRNILASNPRVTRFHINWDNNMDRLEAIETQD

--------------------------------------------------------------
>44402_44402_14_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558013_ASF1B_chr19_14237049_ENST00000474890_length(transcript)=1549nt_BP=1011nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGTTCCAGTGCCAAGACG
GGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGACGTGCTTGTCTGTCA
CCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCCAAGTGGACTGCGACA
ACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCG
TCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACA
GCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTC
TTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTG
ATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAA
ACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCG
AGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAG
ATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGG
TGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCCATCCCTCATCCCAGAGACTGATGCCG
TGGGTGTGACTGTGGTCCTCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTACTACGTCAACAACGAGTACCTCAACC
CTGAGCTGCGTGAGAACCCGCCCATGAAGCCAGATTTCTCCCAGGTGGGGCCTGTTTCCACTTCCTGCTTCCCACAAGGCCGTTCTTTAT
ACTTGGGGGGAGTTCAGCCATTCAAATTGAGAGTCAAGGTCACTTCTTAAGGTTTTCAAGTAATATTCAGTTCTTACAGTACTGTGTTAG
AAGAGGAGAAAAAGACCTTTGTCTCTCAAAGGCATGTCTTAGAGAATTAAGATTAGGCCAGCCTGGGCAACATAGTGAGACCCTGTCCCT

>44402_44402_14_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558013_ASF1B_chr19_14237049_ENST00000474890_length(amino acids)=448AA_BP=319
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQAD

--------------------------------------------------------------
>44402_44402_15_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558013_ASF1B_chr19_14237049_ENST00000592798_length(transcript)=1574nt_BP=1011nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGTTCCAGTGCCAAGACG
GGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGACGTGCTTGTCTGTCA
CCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCCAAGTGGACTGCGACA
ACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCG
TCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACA
GCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTC
TTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTG
ATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAA
ACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCG
AGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAG
ATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGAGGAATTTGATCAGATCCTAGACTCGG
TGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGCTCCAGCGGAACATCTTGGCCTCGAACCCCCGGGTGACCCGCT
TCCATATCAACTGGGACAACAACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCTGGGCTGCGGCCTCCCACTCAACTGCA
CTCCTATCAAGGGCTTGGGGCTCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGACTGCATCTAACTGCAGGAACCCAGAG
TGTCCCAGCACGCCGGGAGGGGCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGGACTTTGGGGGCCATCAGCTGCAATCC
AGGTCTGTCAAACTCAGCCCCTAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAAGGATGATCTCGCTTTTCCTCTACAGG

>44402_44402_15_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558013_ASF1B_chr19_14237049_ENST00000592798_length(amino acids)=426AA_BP=319
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQLQ

--------------------------------------------------------------
>44402_44402_16_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558518_ASF1B_chr19_14237049_ENST00000263382_length(transcript)=2577nt_BP=1127nt
CTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGAC
GTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGC
TGCGAGCATGGGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGA
AAGAAACGAGTTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGA
GTCCCAGGAGACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAG
GTGCGATGGCCAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGA
TGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTG
TGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGA
TGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGA
GTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCC
TGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGT
TGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACAT
GGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGA
GGAATTTGATCAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCC
ATCCCTCATCCCAGAGACTGATGCCGTGGGTGTGACTGTGGTCCTCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTA
CTACGTCAACAACGAGTACCTCAACCCTGAGCTGCGTGAGAACCCGCCCATGAAGCCAGATTTCTCCCAGCTCCAGCGGAACATCTTGGC
CTCGAACCCCCGGGTGACCCGCTTCCATATCAACTGGGACAACAACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCTGGG
CTGCGGCCTCCCACTCAACTGCACTCCTATCAAGGGCTTGGGGCTCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGACTG
CATCTAACTGCAGGAACCCAGAGTGTCCCAGCACGCCGGGAGGGGCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGGACT
TTGGGGGCCATCAGCTGCAATCCAGGTCTGTCAAACTCAGCCCCTAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAAGGA
TGATCTCGCTTTTCCTCTACAGGCCTATAAGAAGCAGGTACTTCAGTTCTAAATTCTGACTTGTGTTCTTTTCGTCTTCATAAATTCTAA
CTAAGGCCACTGTGCCACTGTGCACCCTTGAGTACCATTGATCCAAAGCTTTCCCACAGACCTCCCTGGCCCACCTAGAGGCTTTCTTGG
TCAGTGCCTGTCAAGGCTCCAGTCCTGCTGAGCCAAAGGCTTTGTCATTCCTTTCTCTTCCTGTACATCTGAGCAGACCCACTCCAGCTT
TCTGGTGTCACAGGCGGGAATGTTAGTTAGTAGGTAGACTTAGATCCCATTTCTGTCCTGCTCCCAGGAAGATTCTTAGGTCCTCTTCAA
TCCAGCAGCCCCTCCCAGAGGTGTGATCAGCAGGATGCTGAGGAACCATGTTGCCTTTCCTGTCAATCACAGCCACCTTCCTGTTATCTC
CTAAATGGATCTGGCTTTTCCTGGAGGCTGCCATGGTTGGAAGATGGTATCAGAGGGCCTGCCTGGGCAGTCTGTCTCCGGGCCAGGGTC
AGGGACCCTCTGCCTCTGGCAGCCTTAACCTGTCCTCTGCTAGGACCAGGGTGATTTCAAGCCAGGGAAGCAACTGGGACCCTGAAAACT
GTCCCTCCCCAGCCCGCTCCCCCTCTCTGTGCCCTGGTCCCCTTGCTGCCATGTGGATGCTGTTGTGATTGCTGTTTGTATATTATCAAA

>44402_44402_16_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558518_ASF1B_chr19_14237049_ENST00000263382_length(amino acids)=485AA_BP=319
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQAD
APNPSLIPETDAVGVTVVLITCTYHGQEFIRVGYYVNNEYLNPELRENPPMKPDFSQLQRNILASNPRVTRFHINWDNNMDRLEAIETQD

--------------------------------------------------------------
>44402_44402_17_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558518_ASF1B_chr19_14237049_ENST00000474890_length(transcript)=1665nt_BP=1127nt
CTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGAC
GTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGC
TGCGAGCATGGGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGA
AAGAAACGAGTTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGA
GTCCCAGGAGACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAG
GTGCGATGGCCAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGA
TGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTG
TGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGA
TGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGA
GTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCC
TGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGT
TGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACAT
GGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGA
GGAATTTGATCAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGGCCGACGCCCCCAACCC
ATCCCTCATCCCAGAGACTGATGCCGTGGGTGTGACTGTGGTCCTCATCACCTGCACCTACCATGGACAGGAGTTCATCCGAGTGGGCTA
CTACGTCAACAACGAGTACCTCAACCCTGAGCTGCGTGAGAACCCGCCCATGAAGCCAGATTTCTCCCAGGTGGGGCCTGTTTCCACTTC
CTGCTTCCCACAAGGCCGTTCTTTATACTTGGGGGGAGTTCAGCCATTCAAATTGAGAGTCAAGGTCACTTCTTAAGGTTTTCAAGTAAT
ATTCAGTTCTTACAGTACTGTGTTAGAAGAGGAGAAAAAGACCTTTGTCTCTCAAAGGCATGTCTTAGAGAATTAAGATTAGGCCAGCCT

>44402_44402_17_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558518_ASF1B_chr19_14237049_ENST00000474890_length(amino acids)=448AA_BP=319
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQAD

--------------------------------------------------------------
>44402_44402_18_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558518_ASF1B_chr19_14237049_ENST00000592798_length(transcript)=1690nt_BP=1127nt
CTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGAC
GTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGC
TGCGAGCATGGGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGA
AAGAAACGAGTTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGA
GTCCCAGGAGACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAG
GTGCGATGGCCAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGA
TGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTG
TGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGA
TGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGA
GTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCC
TGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGT
TGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACAT
GGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGACCTGGAGTGGAAGATCATTTATGTTGGCTCGGCTGAGAGTGA
GGAATTTGATCAGATCCTAGACTCGGTGCTGGTGGGCCCTGTGCCAGCAGGGAGACACATGTTTGTCTTTCAGCTCCAGCGGAACATCTT
GGCCTCGAACCCCCGGGTGACCCGCTTCCATATCAACTGGGACAACAACATGGACAGGCTGGAGGCCATAGAGACCCAGGACCCCTCCCT
GGGCTGCGGCCTCCCACTCAACTGCACTCCTATCAAGGGCTTGGGGCTCCCTGGCTGCATCCCTGGCCTCCTCCCTGAGAACTCCATGGA
CTGCATCTAACTGCAGGAACCCAGAGTGTCCCAGCACGCCGGGAGGGGCAACCAGGCCTCCCAGCGAGTCCTGCAGGGCCCATCTAGAGG
ACTTTGGGGGCCATCAGCTGCAATCCAGGTCTGTCAAACTCAGCCCCTAGGAAAGAACAGGCCTTGGGTCTCCCCTAGTCCTGGCCAGAA

>44402_44402_18_LDLR-ASF1B_LDLR_chr19_11218190_ENST00000558518_ASF1B_chr19_14237049_ENST00000592798_length(amino acids)=426AA_BP=319
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECDLEWKIIYVGSAESEEFDQILDSVLVGPVPAGRHMFVFQLQ

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LDLR-ASF1B


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
TgeneASF1Bchr19:11218190chr19:14237049ENST00000263382041_15536.333333333333336203.0CHAF1B
TgeneASF1Bchr19:11218190chr19:14237049ENST00000263382041_15636.333333333333336203.0histone H3


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LDLR-ASF1B


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LDLR-ASF1B


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource