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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LDLR-TNPO2 (FusionGDB2 ID:44419)

Fusion Gene Summary for LDLR-TNPO2

check button Fusion gene summary
Fusion gene informationFusion gene name: LDLR-TNPO2
Fusion gene ID: 44419
HgeneTgene
Gene symbol

LDLR

TNPO2

Gene ID

3949

30000

Gene namelow density lipoprotein receptortransportin 2
SynonymsFH|FHC|FHCL1|LDLCQ2IPO3|KPNB2B|TRN2
Cytomap

19p13.2

19p13.13

Type of geneprotein-codingprotein-coding
Descriptionlow-density lipoprotein receptorLDL receptorlow-density lipoprotein receptor class A domain-containing protein 3transportin-2importin 3karyopherin beta 2b, transportinkaryopherin beta-2btransportin 2 (importin 3, karyopherin beta 2b)
Modification date2020032220200313
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000455727, ENST00000535915, 
ENST00000545707, ENST00000557933, 
ENST00000558013, ENST00000558518, 
ENST00000560628, 		ENST00000425528, 
ENST00000441499, ENST00000588216, 
ENST00000356861, ENST00000450764, 
ENST00000589956, ENST00000592287, 
Fusion gene scores* DoF score23 X 17 X 15=58658 X 11 X 4=352
# samples 3311
** MAII scorelog2(33/5865*10)=-4.15159317867005
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(11/352*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LDLR [Title/Abstract] AND TNPO2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLDLR(11240346)-TNPO2(12834751), # samples:2
LDLR(11234020)-TNPO2(12817609), # samples:2
LDLR(11240346)-TNPO2(12834179), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across LDLR (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across TNPO2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-BH-A1FE-01ALDLRchr19

11240346

-TNPO2chr19

12834179

-
ChimerDB4BRCATCGA-BH-A1FE-01ALDLRchr19

11240346

+TNPO2chr19

12834179

-
ChimerDB4BRCATCGA-BH-A1FE-01ALDLRchr19

11240346

+TNPO2chr19

12834751

-
ChimerDB4SARCTCGA-IE-A6BZ-01ALDLRchr19

11234020

-TNPO2chr19

12817609

-
ChimerDB4SARCTCGA-IE-A6BZ-01ALDLRchr19

11234020

+TNPO2chr19

12817609

-


Top

Fusion Gene ORF analysis for LDLR-TNPO2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000455727ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000455727ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000455727ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000455727ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000455727ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000455727ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000535915ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000535915ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000535915ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000535915ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000535915ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000535915ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000545707ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000545707ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000545707ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000545707ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000545707ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000545707ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000557933ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000557933ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000557933ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000557933ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000557933ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000557933ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000558013ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000558013ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000558013ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000558013ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000558013ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000558013ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000558518ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000558518ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000558518ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000558518ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-5UTRENST00000558518ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-5UTRENST00000558518ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000455727ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000455727ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000455727ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000455727ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000455727ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000455727ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000455727ENST00000589956LDLRchr19

11234020

+TNPO2chr19

12817609

-
5CDS-intronENST00000455727ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000455727ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000535915ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000535915ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000535915ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000535915ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000535915ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000535915ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000535915ENST00000589956LDLRchr19

11234020

+TNPO2chr19

12817609

-
5CDS-intronENST00000535915ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000535915ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000545707ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000545707ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000545707ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000545707ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000545707ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000545707ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000545707ENST00000589956LDLRchr19

11234020

+TNPO2chr19

12817609

-
5CDS-intronENST00000545707ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000545707ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000557933ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000557933ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000557933ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000557933ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000557933ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000557933ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000557933ENST00000589956LDLRchr19

11234020

+TNPO2chr19

12817609

-
5CDS-intronENST00000557933ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000557933ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000558013ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000558013ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000558013ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000558013ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000558013ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000558013ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000558013ENST00000589956LDLRchr19

11234020

+TNPO2chr19

12817609

-
5CDS-intronENST00000558013ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000558013ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000558518ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000558518ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000558518ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000558518ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000558518ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000558518ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834751

-
5CDS-intronENST00000558518ENST00000589956LDLRchr19

11234020

+TNPO2chr19

12817609

-
5CDS-intronENST00000558518ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834179

-
5CDS-intronENST00000558518ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834751

-
In-frameENST00000455727ENST00000356861LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000455727ENST00000425528LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000455727ENST00000441499LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000455727ENST00000450764LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000455727ENST00000588216LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000455727ENST00000592287LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000535915ENST00000356861LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000535915ENST00000425528LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000535915ENST00000441499LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000535915ENST00000450764LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000535915ENST00000588216LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000535915ENST00000592287LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000545707ENST00000356861LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000545707ENST00000425528LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000545707ENST00000441499LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000545707ENST00000450764LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000545707ENST00000588216LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000545707ENST00000592287LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000557933ENST00000356861LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000557933ENST00000425528LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000557933ENST00000441499LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000557933ENST00000450764LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000557933ENST00000588216LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000557933ENST00000592287LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558013ENST00000356861LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558013ENST00000425528LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558013ENST00000441499LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558013ENST00000450764LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558013ENST00000588216LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558013ENST00000592287LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558518ENST00000356861LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558518ENST00000425528LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558518ENST00000441499LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558518ENST00000450764LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558518ENST00000588216LDLRchr19

11234020

+TNPO2chr19

12817609

-
In-frameENST00000558518ENST00000592287LDLRchr19

11234020

+TNPO2chr19

12817609

-
intron-3CDSENST00000560628ENST00000356861LDLRchr19

11234020

+TNPO2chr19

12817609

-
intron-3CDSENST00000560628ENST00000425528LDLRchr19

11234020

+TNPO2chr19

12817609

-
intron-3CDSENST00000560628ENST00000441499LDLRchr19

11234020

+TNPO2chr19

12817609

-
intron-3CDSENST00000560628ENST00000450764LDLRchr19

11234020

+TNPO2chr19

12817609

-
intron-3CDSENST00000560628ENST00000588216LDLRchr19

11234020

+TNPO2chr19

12817609

-
intron-3CDSENST00000560628ENST00000592287LDLRchr19

11234020

+TNPO2chr19

12817609

-
intron-5UTRENST00000560628ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834179

-
intron-5UTRENST00000560628ENST00000425528LDLRchr19

11240346

+TNPO2chr19

12834751

-
intron-5UTRENST00000560628ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834179

-
intron-5UTRENST00000560628ENST00000441499LDLRchr19

11240346

+TNPO2chr19

12834751

-
intron-5UTRENST00000560628ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834179

-
intron-5UTRENST00000560628ENST00000588216LDLRchr19

11240346

+TNPO2chr19

12834751

-
intron-intronENST00000560628ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834179

-
intron-intronENST00000560628ENST00000356861LDLRchr19

11240346

+TNPO2chr19

12834751

-
intron-intronENST00000560628ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834179

-
intron-intronENST00000560628ENST00000450764LDLRchr19

11240346

+TNPO2chr19

12834751

-
intron-intronENST00000560628ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834179

-
intron-intronENST00000560628ENST00000589956LDLRchr19

11240346

+TNPO2chr19

12834751

-
intron-intronENST00000560628ENST00000589956LDLRchr19

11234020

+TNPO2chr19

12817609

-
intron-intronENST00000560628ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834179

-
intron-intronENST00000560628ENST00000592287LDLRchr19

11240346

+TNPO2chr19

12834751

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000558518LDLRchr1911234020+ENST00000425528TNPO2chr1912817609-5992249816939211250
ENST00000558518LDLRchr1911234020+ENST00000441499TNPO2chr1912817609-5962249816938911240
ENST00000558518LDLRchr1911234020+ENST00000356861TNPO2chr1912817609-5955249816938911240
ENST00000558518LDLRchr1911234020+ENST00000450764TNPO2chr1912817609-5483249816938911240
ENST00000558518LDLRchr1911234020+ENST00000592287TNPO2chr1912817609-4033249816939211250
ENST00000558518LDLRchr1911234020+ENST00000588216TNPO2chr1912817609-3911249816938911240
ENST00000557933LDLRchr1911234020+ENST00000425528TNPO2chr1912817609-589223986938211250
ENST00000557933LDLRchr1911234020+ENST00000441499TNPO2chr1912817609-586223986937911240
ENST00000557933LDLRchr1911234020+ENST00000356861TNPO2chr1912817609-585523986937911240
ENST00000557933LDLRchr1911234020+ENST00000450764TNPO2chr1912817609-538323986937911240
ENST00000557933LDLRchr1911234020+ENST00000592287TNPO2chr1912817609-393323986938211250
ENST00000557933LDLRchr1911234020+ENST00000588216TNPO2chr1912817609-381123986937911240
ENST00000455727LDLRchr1911234020+ENST00000425528TNPO2chr1912817609-538718936833161082
ENST00000455727LDLRchr1911234020+ENST00000441499TNPO2chr1912817609-535718936832861072
ENST00000455727LDLRchr1911234020+ENST00000356861TNPO2chr1912817609-535018936832861072
ENST00000455727LDLRchr1911234020+ENST00000450764TNPO2chr1912817609-487818936832861072
ENST00000455727LDLRchr1911234020+ENST00000592287TNPO2chr1912817609-342818936833161082
ENST00000455727LDLRchr1911234020+ENST00000588216TNPO2chr1912817609-330618936832861072
ENST00000535915LDLRchr1911234020+ENST00000425528TNPO2chr1912817609-576822746836971209
ENST00000535915LDLRchr1911234020+ENST00000441499TNPO2chr1912817609-573822746836671199
ENST00000535915LDLRchr1911234020+ENST00000356861TNPO2chr1912817609-573122746836671199
ENST00000535915LDLRchr1911234020+ENST00000450764TNPO2chr1912817609-525922746836671199
ENST00000535915LDLRchr1911234020+ENST00000592287TNPO2chr1912817609-380922746836971209
ENST00000535915LDLRchr1911234020+ENST00000588216TNPO2chr1912817609-368722746836671199
ENST00000545707LDLRchr1911234020+ENST00000425528TNPO2chr1912817609-535718636832861072
ENST00000545707LDLRchr1911234020+ENST00000441499TNPO2chr1912817609-532718636832561062
ENST00000545707LDLRchr1911234020+ENST00000356861TNPO2chr1912817609-532018636832561062
ENST00000545707LDLRchr1911234020+ENST00000450764TNPO2chr1912817609-484818636832561062
ENST00000545707LDLRchr1911234020+ENST00000592287TNPO2chr1912817609-339818636832861072
ENST00000545707LDLRchr1911234020+ENST00000588216TNPO2chr1912817609-327618636832561062
ENST00000558013LDLRchr1911234020+ENST00000425528TNPO2chr1912817609-587623825338051250
ENST00000558013LDLRchr1911234020+ENST00000441499TNPO2chr1912817609-584623825337751240
ENST00000558013LDLRchr1911234020+ENST00000356861TNPO2chr1912817609-583923825337751240
ENST00000558013LDLRchr1911234020+ENST00000450764TNPO2chr1912817609-536723825337751240
ENST00000558013LDLRchr1911234020+ENST00000592287TNPO2chr1912817609-391723825338051250
ENST00000558013LDLRchr1911234020+ENST00000588216TNPO2chr1912817609-379523825337751240

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000558518ENST00000425528LDLRchr1911234020+TNPO2chr1912817609-0.0009001760.99909985
ENST00000558518ENST00000441499LDLRchr1911234020+TNPO2chr1912817609-0.001020720.9989793
ENST00000558518ENST00000356861LDLRchr1911234020+TNPO2chr1912817609-0.0010139920.99898595
ENST00000558518ENST00000450764LDLRchr1911234020+TNPO2chr1912817609-0.001734870.9982652
ENST00000558518ENST00000592287LDLRchr1911234020+TNPO2chr1912817609-0.0037817080.99621826
ENST00000558518ENST00000588216LDLRchr1911234020+TNPO2chr1912817609-0.004726590.9952734
ENST00000557933ENST00000425528LDLRchr1911234020+TNPO2chr1912817609-0.0007936340.99920636
ENST00000557933ENST00000441499LDLRchr1911234020+TNPO2chr1912817609-0.0008991550.9991009
ENST00000557933ENST00000356861LDLRchr1911234020+TNPO2chr1912817609-0.0008928580.99910706
ENST00000557933ENST00000450764LDLRchr1911234020+TNPO2chr1912817609-0.0015479530.99845207
ENST00000557933ENST00000592287LDLRchr1911234020+TNPO2chr1912817609-0.0035091870.9964908
ENST00000557933ENST00000588216LDLRchr1911234020+TNPO2chr1912817609-0.0044076210.9955924
ENST00000455727ENST00000425528LDLRchr1911234020+TNPO2chr1912817609-0.0006254450.99937457
ENST00000455727ENST00000441499LDLRchr1911234020+TNPO2chr1912817609-0.0007082640.99929166
ENST00000455727ENST00000356861LDLRchr1911234020+TNPO2chr1912817609-0.0007021730.99929786
ENST00000455727ENST00000450764LDLRchr1911234020+TNPO2chr1912817609-0.0012802990.9987197
ENST00000455727ENST00000592287LDLRchr1911234020+TNPO2chr1912817609-0.0031788020.99682117
ENST00000455727ENST00000588216LDLRchr1911234020+TNPO2chr1912817609-0.0040072590.9959927
ENST00000535915ENST00000425528LDLRchr1911234020+TNPO2chr1912817609-0.0007681720.9992318
ENST00000535915ENST00000441499LDLRchr1911234020+TNPO2chr1912817609-0.0008653930.9991346
ENST00000535915ENST00000356861LDLRchr1911234020+TNPO2chr1912817609-0.0008591530.99914086
ENST00000535915ENST00000450764LDLRchr1911234020+TNPO2chr1912817609-0.0015191190.99848086
ENST00000535915ENST00000592287LDLRchr1911234020+TNPO2chr1912817609-0.0034996250.9965004
ENST00000535915ENST00000588216LDLRchr1911234020+TNPO2chr1912817609-0.0044046750.9955953
ENST00000545707ENST00000425528LDLRchr1911234020+TNPO2chr1912817609-0.0005333890.9994666
ENST00000545707ENST00000441499LDLRchr1911234020+TNPO2chr1912817609-0.0007037620.9992962
ENST00000545707ENST00000356861LDLRchr1911234020+TNPO2chr1912817609-0.0006975340.9993025
ENST00000545707ENST00000450764LDLRchr1911234020+TNPO2chr1912817609-0.0012967360.99870324
ENST00000545707ENST00000592287LDLRchr1911234020+TNPO2chr1912817609-0.0026355870.99736446
ENST00000545707ENST00000588216LDLRchr1911234020+TNPO2chr1912817609-0.0038030540.996197
ENST00000558013ENST00000425528LDLRchr1911234020+TNPO2chr1912817609-0.0007774550.9992225
ENST00000558013ENST00000441499LDLRchr1911234020+TNPO2chr1912817609-0.0008791390.9991209
ENST00000558013ENST00000356861LDLRchr1911234020+TNPO2chr1912817609-0.0008729620.9991271
ENST00000558013ENST00000450764LDLRchr1911234020+TNPO2chr1912817609-0.0015205670.9984794
ENST00000558013ENST00000592287LDLRchr1911234020+TNPO2chr1912817609-0.0034735910.9965264
ENST00000558013ENST00000588216LDLRchr1911234020+TNPO2chr1912817609-0.0043643440.9956357

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Fusion Genomic Features for LDLR-TNPO2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LDLR-TNPO2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:11240346/chr19:12834751)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316107_145602693.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316146_186602693.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316195_233602693.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316234_272602693.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+131625_65602693.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316274_313602693.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316314_353602693.0DomainEGF-like 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316354_393602693.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+131666_106602693.0DomainLDL-receptor class A 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417107_145729820.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417146_186729820.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417195_233729820.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417234_272729820.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+141725_65729820.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417274_313729820.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417314_353729820.0DomainEGF-like 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417354_393729820.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417663_712729820.0DomainEGF-like 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+141766_106729820.0DomainLDL-receptor class A 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316107_145592683.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316146_186592683.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316195_233592683.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316234_272592683.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+131625_65592683.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316274_313592683.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316314_353592683.0DomainEGF-like 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316354_393592683.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+131666_106592683.0DomainLDL-receptor class A 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518107_145770859.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518146_186770859.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518195_233770859.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518234_272770859.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+151825_65770859.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518274_313770859.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518314_353770859.0DomainEGF-like 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518354_393770859.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518663_712770859.0DomainEGF-like 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+151866_106770859.0DomainLDL-receptor class A 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518107_145770861.0DomainLDL-receptor class A 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518146_186770861.0DomainLDL-receptor class A 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518195_233770861.0DomainLDL-receptor class A 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518234_272770861.0DomainLDL-receptor class A 6
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+151825_65770861.0DomainLDL-receptor class A 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518274_313770861.0DomainLDL-receptor class A 7
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518314_353770861.0DomainEGF-like 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518354_393770861.0DomainEGF-like 2%3B calcium-binding
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518663_712770861.0DomainEGF-like 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+151866_106770861.0DomainLDL-receptor class A 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518721_768770859.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518721_768770861.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316397_438602693.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316439_485602693.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316486_528602693.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316529_572602693.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417397_438729820.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417439_485729820.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417486_528729820.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417529_572729820.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417573_615729820.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417616_658729820.0RepeatNote=LDL-receptor class B 6
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316397_438592683.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316439_485592683.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316486_528592683.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316529_572592683.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518397_438770859.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518439_485770859.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518486_528770859.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518529_572770859.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518573_615770859.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518616_658770859.0RepeatNote=LDL-receptor class B 6
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518397_438770861.0RepeatNote=LDL-receptor class B 1
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518439_485770861.0RepeatNote=LDL-receptor class B 2
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518486_528770861.0RepeatNote=LDL-receptor class B 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518529_572770861.0RepeatNote=LDL-receptor class B 4
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518573_615770861.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518616_658770861.0RepeatNote=LDL-receptor class B 6
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125434_4614231500.3333333333333RepeatHEAT 10
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125475_5084231500.3333333333333RepeatHEAT 11
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125516_5494231500.3333333333333RepeatHEAT 12
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125557_5954231500.3333333333333RepeatHEAT 13
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125603_6544231500.3333333333333RepeatHEAT 14
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125665_6964231500.3333333333333RepeatHEAT 15
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125704_7374231500.3333333333333RepeatHEAT 16
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125745_7904231500.3333333333333RepeatHEAT 17
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125798_8314231500.3333333333333RepeatHEAT 18
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125840_8714231500.3333333333333RepeatHEAT 19
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125874_8944231500.3333333333333RepeatHEAT 20
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226434_4614231509.0RepeatHEAT 10
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226475_5084231509.0RepeatHEAT 11
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226516_5494231509.0RepeatHEAT 12
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226557_5954231509.0RepeatHEAT 13
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226603_6544231509.0RepeatHEAT 14
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226665_6964231509.0RepeatHEAT 15
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226704_7374231509.0RepeatHEAT 16
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226745_7904231509.0RepeatHEAT 17
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226798_8314231509.0RepeatHEAT 18
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226840_8714231509.0RepeatHEAT 19
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226874_8944231509.0RepeatHEAT 20
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226434_4614231499.0RepeatHEAT 10
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226475_5084231499.0RepeatHEAT 11
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226516_5494231499.0RepeatHEAT 12
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226557_5954231499.0RepeatHEAT 13
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226603_6544231499.0RepeatHEAT 14
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226665_6964231499.0RepeatHEAT 15
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226704_7374231499.0RepeatHEAT 16
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226745_7904231499.0RepeatHEAT 17
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226798_8314231499.0RepeatHEAT 18
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226840_8714231499.0RepeatHEAT 19
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226874_8944231499.0RepeatHEAT 20
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024434_4614231150.0RepeatHEAT 10
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024475_5084231150.0RepeatHEAT 11
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024516_5494231150.0RepeatHEAT 12
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024557_5954231150.0RepeatHEAT 13
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024603_6544231150.0RepeatHEAT 14
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024665_6964231150.0RepeatHEAT 15
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024704_7374231150.0RepeatHEAT 16
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024745_7904231150.0RepeatHEAT 17
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024798_8314231150.0RepeatHEAT 18
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024840_8714231150.0RepeatHEAT 19
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024874_8944231150.0RepeatHEAT 20
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225434_461423888.0RepeatHEAT 10
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225475_508423888.0RepeatHEAT 11
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225516_549423888.0RepeatHEAT 12
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225557_595423888.0RepeatHEAT 13
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225603_654423888.0RepeatHEAT 14
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225665_696423888.0RepeatHEAT 15
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225704_737423888.0RepeatHEAT 16
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225745_790423888.0RepeatHEAT 17
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225798_831423888.0RepeatHEAT 18
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225840_871423888.0RepeatHEAT 19
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225874_894423888.0RepeatHEAT 20
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125434_461423901.6666666666666RepeatHEAT 10
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125475_508423901.6666666666666RepeatHEAT 11
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125516_549423901.6666666666666RepeatHEAT 12
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125557_595423901.6666666666666RepeatHEAT 13
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125603_654423901.6666666666666RepeatHEAT 14
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125665_696423901.6666666666666RepeatHEAT 15
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125704_737423901.6666666666666RepeatHEAT 16
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125745_790423901.6666666666666RepeatHEAT 17
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125798_831423901.6666666666666RepeatHEAT 18
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125840_871423901.6666666666666RepeatHEAT 19
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125874_894423901.6666666666666RepeatHEAT 20

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316663_712602693.0DomainEGF-like 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316663_712592683.0DomainEGF-like 3
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316823_828602693.0MotifNPXY motif
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417823_828729820.0MotifNPXY motif
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316823_828592683.0MotifNPXY motif
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518823_828770859.0MotifNPXY motif
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518823_828770861.0MotifNPXY motif
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316721_768602693.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316811_860602693.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417721_768729820.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417811_860729820.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316721_768592683.0RegionNote=Clustered O-linked oligosaccharides
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316811_860592683.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518811_860770859.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518811_860770861.0RegionRequired for MYLIP-triggered down-regulation of LDLR
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316573_615602693.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316616_658602693.0RepeatNote=LDL-receptor class B 6
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316573_615592683.0RepeatNote=LDL-receptor class B 5
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316616_658592683.0RepeatNote=LDL-receptor class B 6
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+131622_788602693.0Topological domainExtracellular
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+141722_788729820.0Topological domainExtracellular
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+131622_788592683.0Topological domainExtracellular
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+151822_788770859.0Topological domainExtracellular
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+151822_788770861.0Topological domainExtracellular
HgeneLDLRchr19:11234020chr19:12817609ENST00000455727+1316789_810602693.0TransmembraneHelical
HgeneLDLRchr19:11234020chr19:12817609ENST00000535915+1417789_810729820.0TransmembraneHelical
HgeneLDLRchr19:11234020chr19:12817609ENST00000545707+1316789_810592683.0TransmembraneHelical
HgeneLDLRchr19:11234020chr19:12817609ENST00000558013+1518789_810770859.0TransmembraneHelical
HgeneLDLRchr19:11234020chr19:12817609ENST00000558518+1518789_810770861.0TransmembraneHelical
TgeneTNPO2chr19:11234020chr19:12817609ENST00000356861112531_994231500.3333333333333DomainNote=Importin N-terminal
TgeneTNPO2chr19:11234020chr19:12817609ENST00000425528122631_994231509.0DomainNote=Importin N-terminal
TgeneTNPO2chr19:11234020chr19:12817609ENST00000441499122631_994231499.0DomainNote=Importin N-terminal
TgeneTNPO2chr19:11234020chr19:12817609ENST00000450764102431_994231150.0DomainNote=Importin N-terminal
TgeneTNPO2chr19:11234020chr19:12817609ENST00000588216122531_99423888.0DomainNote=Importin N-terminal
TgeneTNPO2chr19:11234020chr19:12817609ENST00000592287112531_99423901.6666666666666DomainNote=Importin N-terminal
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125127_1644231500.3333333333333RepeatHEAT 4
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125171_2014231500.3333333333333RepeatHEAT 5
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125214_2414231500.3333333333333RepeatHEAT 6
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125253_2804231500.3333333333333RepeatHEAT 7
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125296_3864231500.3333333333333RepeatHEAT 8
TgeneTNPO2chr19:11234020chr19:12817609ENST000003568611125394_4224231500.3333333333333RepeatHEAT 9
TgeneTNPO2chr19:11234020chr19:12817609ENST00000356861112541_794231500.3333333333333RepeatHEAT 2
TgeneTNPO2chr19:11234020chr19:12817609ENST00000356861112588_1214231500.3333333333333RepeatHEAT 3
TgeneTNPO2chr19:11234020chr19:12817609ENST0000035686111259_364231500.3333333333333RepeatHEAT 1
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226127_1644231509.0RepeatHEAT 4
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226171_2014231509.0RepeatHEAT 5
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226214_2414231509.0RepeatHEAT 6
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226253_2804231509.0RepeatHEAT 7
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226296_3864231509.0RepeatHEAT 8
TgeneTNPO2chr19:11234020chr19:12817609ENST000004255281226394_4224231509.0RepeatHEAT 9
TgeneTNPO2chr19:11234020chr19:12817609ENST00000425528122641_794231509.0RepeatHEAT 2
TgeneTNPO2chr19:11234020chr19:12817609ENST00000425528122688_1214231509.0RepeatHEAT 3
TgeneTNPO2chr19:11234020chr19:12817609ENST0000042552812269_364231509.0RepeatHEAT 1
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226127_1644231499.0RepeatHEAT 4
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226171_2014231499.0RepeatHEAT 5
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226214_2414231499.0RepeatHEAT 6
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226253_2804231499.0RepeatHEAT 7
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226296_3864231499.0RepeatHEAT 8
TgeneTNPO2chr19:11234020chr19:12817609ENST000004414991226394_4224231499.0RepeatHEAT 9
TgeneTNPO2chr19:11234020chr19:12817609ENST00000441499122641_794231499.0RepeatHEAT 2
TgeneTNPO2chr19:11234020chr19:12817609ENST00000441499122688_1214231499.0RepeatHEAT 3
TgeneTNPO2chr19:11234020chr19:12817609ENST0000044149912269_364231499.0RepeatHEAT 1
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024127_1644231150.0RepeatHEAT 4
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024171_2014231150.0RepeatHEAT 5
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024214_2414231150.0RepeatHEAT 6
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024253_2804231150.0RepeatHEAT 7
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024296_3864231150.0RepeatHEAT 8
TgeneTNPO2chr19:11234020chr19:12817609ENST000004507641024394_4224231150.0RepeatHEAT 9
TgeneTNPO2chr19:11234020chr19:12817609ENST00000450764102441_794231150.0RepeatHEAT 2
TgeneTNPO2chr19:11234020chr19:12817609ENST00000450764102488_1214231150.0RepeatHEAT 3
TgeneTNPO2chr19:11234020chr19:12817609ENST0000045076410249_364231150.0RepeatHEAT 1
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225127_164423888.0RepeatHEAT 4
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225171_201423888.0RepeatHEAT 5
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225214_241423888.0RepeatHEAT 6
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225253_280423888.0RepeatHEAT 7
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225296_386423888.0RepeatHEAT 8
TgeneTNPO2chr19:11234020chr19:12817609ENST000005882161225394_422423888.0RepeatHEAT 9
TgeneTNPO2chr19:11234020chr19:12817609ENST00000588216122541_79423888.0RepeatHEAT 2
TgeneTNPO2chr19:11234020chr19:12817609ENST00000588216122588_121423888.0RepeatHEAT 3
TgeneTNPO2chr19:11234020chr19:12817609ENST0000058821612259_36423888.0RepeatHEAT 1
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125127_164423901.6666666666666RepeatHEAT 4
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125171_201423901.6666666666666RepeatHEAT 5
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125214_241423901.6666666666666RepeatHEAT 6
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125253_280423901.6666666666666RepeatHEAT 7
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125296_386423901.6666666666666RepeatHEAT 8
TgeneTNPO2chr19:11234020chr19:12817609ENST000005922871125394_422423901.6666666666666RepeatHEAT 9
TgeneTNPO2chr19:11234020chr19:12817609ENST00000592287112541_79423901.6666666666666RepeatHEAT 2
TgeneTNPO2chr19:11234020chr19:12817609ENST00000592287112588_121423901.6666666666666RepeatHEAT 3
TgeneTNPO2chr19:11234020chr19:12817609ENST0000059228711259_36423901.6666666666666RepeatHEAT 1


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Fusion Gene Sequence for LDLR-TNPO2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>44419_44419_1_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000356861_length(transcript)=5350nt_BP=1893nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCA
TCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGG
ACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGC
GAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTG
AGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCA
GGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATA
GAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCA
GCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTG
TTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCT
TCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACA
TTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATG
TCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTT
GGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAG
AGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATC
TGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGA
GCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGC
ACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACC
AAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCT
CCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGC
TCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGG
TGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTG
GCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGC
TCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTG
AGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTC
CCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCA
GCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCA
AAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCA
ACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGG
AAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGG
TGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCG
GCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGA
AGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAAT
TCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGG
AGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGAT
GCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGG
AGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAG
GAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACA
CGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAG
TAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATT
GGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCT
GTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAG
CCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAG
ACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTT
CAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTA
ATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCT
ATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTC
CGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGG
CCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTG
GAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAG
GCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGT
CTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTG
CTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGG
GAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTT
TGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCC
TCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACT

>44419_44419_1_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000356861_length(amino acids)=1072AA_BP=608
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCLTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPD
GFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL
DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAI
VVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA
VFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGM
LLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLS
DKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNL
LILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQ
HPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLN
PEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNE

--------------------------------------------------------------
>44419_44419_2_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000425528_length(transcript)=5387nt_BP=1893nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCA
TCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGG
ACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGC
GAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTG
AGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCA
GGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATA
GAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCA
GCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTG
TTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCT
TCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACA
TTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATG
TCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTT
GGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAG
AGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATC
TGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGA
GCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGC
ACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACC
AAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCT
CCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGC
TCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGG
TGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTG
GCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGC
TCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTG
AGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTC
CCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCA
GCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCA
AAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCA
ACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGG
AAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGGTCGCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCG
GCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGG
ACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCT
GCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGG
AAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGA
CTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTA
GGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGT
GGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCA
GCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGG
GGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGC
TCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGT
TTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGG
GAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCT
CAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCT
CCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCT
ACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTT
TTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGG
AAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACT
AGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGT
AGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTG
GGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCA
AGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCT
GCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCT
GGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACCCCTCGCTAC
TCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATT
TAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACT
GGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGG

>44419_44419_2_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000425528_length(amino acids)=1082AA_BP=608
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCLTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPD
GFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL
DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAI
VVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA
VFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGM
LLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLS
DKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNL
LILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQ
HPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLN
PEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWC
TSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFY

--------------------------------------------------------------
>44419_44419_3_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000441499_length(transcript)=5357nt_BP=1893nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCA
TCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGG
ACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGC
GAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTG
AGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCA
GGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATA
GAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCA
GCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTG
TTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCT
TCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACA
TTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATG
TCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTT
GGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAG
AGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATC
TGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGA
GCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGC
ACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACC
AAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCT
CCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGC
TCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGG
TGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTG
GCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGC
TCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTG
AGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTC
CCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCA
GCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCA
AAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCA
ACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGG
AAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGG
TGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCG
GCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGA
AGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAAT
TCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGG
AGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGAT
GCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGG
AGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAG
GAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACA
CGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAG
TAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATT
GGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCT
GTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAG
CCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAG
ACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTT
CAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTA
ATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCT
ATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTC
CGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGG
CCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTG
GAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAG
GCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGT
CTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTG
CTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGG
GAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTT
TGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCC
TCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACT

>44419_44419_3_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000441499_length(amino acids)=1072AA_BP=608
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCLTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPD
GFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL
DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAI
VVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA
VFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGM
LLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLS
DKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNL
LILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQ
HPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLN
PEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNE

--------------------------------------------------------------
>44419_44419_4_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000450764_length(transcript)=4878nt_BP=1893nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCA
TCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGG
ACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGC
GAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTG
AGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCA
GGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATA
GAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCA
GCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTG
TTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCT
TCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACA
TTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATG
TCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTT
GGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAG
AGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATC
TGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGA
GCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGC
ACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACC
AAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCT
CCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGC
TCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGG
TGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTG
GCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGC
TCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTG
AGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTC
CCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCA
GCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCA
AAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCA
ACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGG
AAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGG
TGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCG
GCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGA
AGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAAT
TCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGG
AGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGAT
GCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGG
AGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAG
GAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACA
CGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAG
TAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATT
GGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCT
GTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAG
CCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAG
ACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTT
CAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTA
ATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCT
ATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTC
CGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGG
CCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTG
GAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAG
GCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGT

>44419_44419_4_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000450764_length(amino acids)=1072AA_BP=608
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCLTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPD
GFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL
DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAI
VVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA
VFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGM
LLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLS
DKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNL
LILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQ
HPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLN
PEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNE

--------------------------------------------------------------
>44419_44419_5_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000588216_length(transcript)=3306nt_BP=1893nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCA
TCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGG
ACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGC
GAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTG
AGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCA
GGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATA
GAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCA
GCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTG
TTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCT
TCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACA
TTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATG
TCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTT
GGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAG
AGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATC
TGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGA
GCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGC
ACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACC
AAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCT
CCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGC
TCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGG
TGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTG
GCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGC
TCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTG
AGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTC
CCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCA
GCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCA
AAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCA
ACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGG
AAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGG
TGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCG
GCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGA
AGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAAT

>44419_44419_5_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000588216_length(amino acids)=1072AA_BP=608
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCLTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPD
GFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL
DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAI
VVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA
VFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGM
LLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLS
DKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNL
LILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQ
HPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLN
PEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNE

--------------------------------------------------------------
>44419_44419_6_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000592287_length(transcript)=3428nt_BP=1893nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCA
TCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGG
ACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGC
GAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTG
AGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCA
GGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATA
GAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCA
GCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTG
TTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCT
TCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACA
TTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATG
TCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTT
GGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAG
AGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATC
TGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGA
GCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGC
ACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACC
AAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCT
CCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGC
TCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGG
TGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTG
GCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGC
TCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTG
AGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTC
CCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCA
GCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCA
AAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCA
ACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGG
AAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGGTCGCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCG
GCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGG
ACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCT
GCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGG
AAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGA
CTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTA

>44419_44419_6_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000455727_TNPO2_chr19_12817609_ENST00000592287_length(amino acids)=1082AA_BP=608
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCLTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPD
GFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVAL
DTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAI
VVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLA
VFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGM
LLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLS
DKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNL
LILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQ
HPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLN
PEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWC
TSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRDMFYKILHGFKDQVGEDNWQQFSEQFPPLLKERLAAFY

--------------------------------------------------------------
>44419_44419_7_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000356861_length(transcript)=5731nt_BP=2274nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGG
ACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCC
AGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGG
ACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCA
AGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCC
GGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCA
AGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGT
GCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACG
GCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGG
GTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCT
TCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGG
ACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCT
CTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACT
CTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCG
TGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCT
ACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTC
ACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCG
TCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGG
CTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGA
GCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGC
TGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCT
CCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGG
AGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGG
ATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCA
AGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGG
AAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGC
TCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCAC
TGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGA
GTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGC
ACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACG
TGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTG
CCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACC
CAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGA
TGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGG
GCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGG
AGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTG
TAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACT
GGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGT
TTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGT
GAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACC
ATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTG
GGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTC
GTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATT
TCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGC
TTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGAT
GGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTG
GTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGT
GTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGC
ATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAA
GGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAG
GTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGT
CAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTC
CCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCC
TTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTG
TCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCA
CCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCC
AGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGG
GGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTT
AATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAG
CCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCC

>44419_44419_7_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000356861_length(amino acids)=1199AA_BP=735
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGKCISRQ
FVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWR
CDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW
SDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAV
GSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIH
SNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRL
YWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVN
WCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGA
TPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAAC
SAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLS
SVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMP
EVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT
AITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRDMFYKILHGFK

--------------------------------------------------------------
>44419_44419_8_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000425528_length(transcript)=5768nt_BP=2274nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGG
ACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCC
AGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGG
ACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCA
AGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCC
GGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCA
AGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGT
GCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACG
GCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGG
GTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCT
TCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGG
ACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCT
CTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACT
CTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCG
TGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCT
ACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTC
ACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCG
TCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGG
CTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGA
GCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGC
TGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCT
CCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGG
AGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGG
ATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCA
AGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGG
AAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGC
TCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCAC
TGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGA
GTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGC
ACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACG
TGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTG
CCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACC
CAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGA
TGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGGTCGCCTGACGAGTCCCTCTG
CCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCA
CGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTG
TGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACG
GCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATG
GGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTG
TGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCAC
TTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCT
CTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTG
AGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCATAAC
CGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTC
CGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCA
GGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACACTCC
CTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGC
TGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTG
TAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTT
CTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAA
AGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCC
AGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTC
CCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCT
TCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCT
GGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCC
ATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTT
AAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATG
GGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTT
TTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTAC
CCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATT
TGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACTTGTGTAGAACTTTGTTGAGTAAAGATCAGTTTCTTGTGA

>44419_44419_8_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000425528_length(amino acids)=1209AA_BP=735
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGKCISRQ
FVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWR
CDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW
SDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAV
GSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIH
SNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRL
YWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVN
WCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGA
TPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAAC
SAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLS
SVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMP
EVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT
GRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRD

--------------------------------------------------------------
>44419_44419_9_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000441499_length(transcript)=5738nt_BP=2274nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGG
ACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCC
AGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGG
ACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCA
AGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCC
GGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCA
AGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGT
GCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACG
GCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGG
GTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCT
TCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGG
ACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCT
CTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACT
CTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCG
TGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCT
ACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTC
ACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCG
TCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGG
CTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGA
GCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGC
TGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCT
CCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGG
AGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGG
ATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCA
AGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGG
AAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGC
TCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCAC
TGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGA
GTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGC
ACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACG
TGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTG
CCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACC
CAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGA
TGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGG
GCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGG
AGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTG
TAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACT
GGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGT
TTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGT
GAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACC
ATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTG
GGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTC
GTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATT
TCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGC
TTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGAT
GGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTG
GTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGT
GTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGC
ATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAA
GGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAG
GTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGT
CAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTC
CCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCC
TTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTG
TCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCA
CCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCC
AGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGG
GGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTT
AATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAG
CCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCC

>44419_44419_9_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000441499_length(amino acids)=1199AA_BP=735
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGKCISRQ
FVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWR
CDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW
SDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAV
GSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIH
SNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRL
YWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVN
WCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGA
TPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAAC
SAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLS
SVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMP
EVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT
AITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRDMFYKILHGFK

--------------------------------------------------------------
>44419_44419_10_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000450764_length(transcript)=5259nt_BP=2274nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGG
ACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCC
AGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGG
ACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCA
AGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCC
GGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCA
AGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGT
GCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACG
GCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGG
GTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCT
TCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGG
ACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCT
CTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACT
CTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCG
TGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCT
ACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTC
ACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCG
TCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGG
CTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGA
GCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGC
TGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCT
CCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGG
AGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGG
ATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCA
AGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGG
AAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGC
TCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCAC
TGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGA
GTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGC
ACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACG
TGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTG
CCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACC
CAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGA
TGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGG
GCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGG
AGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTG
TAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACT
GGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGT
TTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGT
GAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACC
ATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTG
GGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTC
GTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATT
TCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGC
TTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGAT
GGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTG
GTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGT
GTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGC
ATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAA
GGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAG
GTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGT
CAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTC
CCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCC
TTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTG
TCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCA

>44419_44419_10_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000450764_length(amino acids)=1199AA_BP=735
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGKCISRQ
FVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWR
CDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW
SDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAV
GSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIH
SNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRL
YWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVN
WCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGA
TPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAAC
SAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLS
SVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMP
EVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT
AITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRDMFYKILHGFK

--------------------------------------------------------------
>44419_44419_11_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000588216_length(transcript)=3687nt_BP=2274nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGG
ACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCC
AGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGG
ACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCA
AGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCC
GGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCA
AGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGT
GCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACG
GCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGG
GTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCT
TCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGG
ACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCT
CTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACT
CTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCG
TGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCT
ACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTC
ACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCG
TCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGG
CTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGA
GCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGC
TGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCT
CCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGG
AGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGG
ATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCA
AGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGG
AAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGC
TCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCAC
TGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGA
GTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGC
ACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACG
TGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTG
CCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACC
CAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGA
TGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGG
GCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGG
AGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTG
TAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACT

>44419_44419_11_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000588216_length(amino acids)=1199AA_BP=735
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGKCISRQ
FVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWR
CDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW
SDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAV
GSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIH
SNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRL
YWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVN
WCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGA
TPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAAC
SAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLS
SVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMP
EVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT
AITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRDMFYKILHGFK

--------------------------------------------------------------
>44419_44419_12_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000592287_length(transcript)=3809nt_BP=2274nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGG
ACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCC
AGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGG
ACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCA
AGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCC
GGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCA
AGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGT
GCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACG
GCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGG
GTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCT
TCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGG
ACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCT
CTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACT
CTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCG
TGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCT
ACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTC
ACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCG
TCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGG
CTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGA
GCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGC
TGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCT
CCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGG
AGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGG
ATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCA
AGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGG
AAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGC
TCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCAC
TGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGA
GTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGC
ACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACG
TGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTG
CCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACC
CAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGA
TGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGGTCGCCTGACGAGTCCCTCTG
CCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCA
CGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTG
TGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACG
GCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATG
GGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTG

>44419_44419_12_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000535915_TNPO2_chr19_12817609_ENST00000592287_length(amino acids)=1209AA_BP=735
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCSPKTCSQDEFRCHDGKCISRQ
FVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCEDGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWR
CDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDW
SDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAV
GSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIH
SNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRL
YWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVN
WCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTEAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGA
TPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAAC
SAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLS
SVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMP
EVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENT
GRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMMIGVNPGGVVQDFIFFCDAVASWVSPKDDLRD

--------------------------------------------------------------
>44419_44419_13_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000356861_length(transcript)=5320nt_BP=1863nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCA
TCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGAC
CCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAAC
CCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCC
TGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCG
TGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCG
CCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACG
TGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAG
CCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCT
ACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGC
CAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATG
GTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTG
ACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCT
TCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATG
TCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGAGGCTGAGGCTGCAGTGG
CCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCT
CCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACC
TGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATG
CCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGG
TACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCC
TTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACC
TCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCC
TGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGG
TGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGG
ATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCA
TGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTA
TCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCT
GCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGA
CACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGC
CTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGG
GGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGA
TTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGG
CTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGG
AAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCA
TCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGC
CCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCG
GATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGG
TGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGT
AAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGG
GGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCC
ACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGT
GGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAG
AGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGA
AACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTG
CCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATC
ATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGG
AAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCT
TTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCC
ATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGT
ACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAA
AAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGC
TGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCT
TTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTT
CTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGT
CTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACTTGTGTAGAACTTTGTTGAGTAAAGATCAGT

>44419_44419_13_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000356861_length(amino acids)=1062AA_BP=598
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARD
CRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKA
CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAV
DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLL
SGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQP
REAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIA
CWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTL
ADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDK
DFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNA
TWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGIC

--------------------------------------------------------------
>44419_44419_14_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000425528_length(transcript)=5357nt_BP=1863nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCA
TCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGAC
CCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAAC
CCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCC
TGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCG
TGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCG
CCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACG
TGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAG
CCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCT
ACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGC
CAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATG
GTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTG
ACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCT
TCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATG
TCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGAGGCTGAGGCTGCAGTGG
CCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCT
CCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACC
TGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATG
CCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGG
TACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCC
TTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACC
TCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCC
TGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGG
TGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGG
ATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCA
TGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTA
TCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCT
GCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGA
CACTGCTGGAAAACACAGGTCGCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGG
TGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCG
GCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGA
AGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAAT
TCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGG
AGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGAT
GCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGG
AGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAG
GAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACA
CGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAG
TAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATT
GGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCT
GTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAG
CCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAG
ACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTT
CAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTA
ATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCT
ATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTC
CGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGG
CCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTG
GAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAG
GCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGT
CTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTG
CTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGG
GAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTT
TGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCC
TCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACT

>44419_44419_14_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000425528_length(amino acids)=1072AA_BP=598
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARD
CRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKA
CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAV
DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLL
SGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQP
REAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIA
CWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTL
ADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDK
DFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNA
TWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNE

--------------------------------------------------------------
>44419_44419_15_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000441499_length(transcript)=5327nt_BP=1863nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCA
TCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGAC
CCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAAC
CCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCC
TGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCG
TGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCG
CCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACG
TGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAG
CCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCT
ACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGC
CAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATG
GTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTG
ACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCT
TCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATG
TCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGAGGCTGAGGCTGCAGTGG
CCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCT
CCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACC
TGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATG
CCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGG
TACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCC
TTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACC
TCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCC
TGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGG
TGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGG
ATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCA
TGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTA
TCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCT
GCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGA
CACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGC
CTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGG
GGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGA
TTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGG
CTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGG
AAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCA
TCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGC
CCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCG
GATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGG
TGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGT
AAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGG
GGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCC
ACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGT
GGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAG
AGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGA
AACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTG
CCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATC
ATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGG
AAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCT
TTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCC
ATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGT
ACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAA
AAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGC
TGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCT
TTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTT
CTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGT
CTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACTTGTGTAGAACTTTGTTGAGTAAAGATCAGT

>44419_44419_15_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000441499_length(amino acids)=1062AA_BP=598
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARD
CRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKA
CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAV
DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLL
SGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQP
REAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIA
CWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTL
ADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDK
DFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNA
TWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGIC

--------------------------------------------------------------
>44419_44419_16_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000450764_length(transcript)=4848nt_BP=1863nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCA
TCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGAC
CCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAAC
CCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCC
TGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCG
TGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCG
CCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACG
TGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAG
CCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCT
ACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGC
CAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATG
GTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTG
ACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCT
TCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATG
TCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGAGGCTGAGGCTGCAGTGG
CCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCT
CCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACC
TGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATG
CCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGG
TACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCC
TTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACC
TCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCC
TGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGG
TGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGG
ATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCA
TGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTA
TCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCT
GCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGA
CACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGC
CTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGG
GGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGA
TTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGG
CTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGG
AAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCA
TCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGC
CCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCG
GATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGG
TGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGT
AAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGG
GGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCC
ACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGT
GGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAG
AGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGA
AACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTG
CCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATC
ATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGG
AAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCT
TTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCC
ATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGT

>44419_44419_16_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000450764_length(amino acids)=1062AA_BP=598
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARD
CRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKA
CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAV
DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLL
SGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQP
REAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIA
CWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTL
ADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDK
DFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNA
TWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGIC

--------------------------------------------------------------
>44419_44419_17_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000588216_length(transcript)=3276nt_BP=1863nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCA
TCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGAC
CCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAAC
CCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCC
TGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCG
TGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCG
CCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACG
TGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAG
CCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCT
ACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGC
CAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATG
GTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTG
ACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCT
TCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATG
TCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGAGGCTGAGGCTGCAGTGG
CCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCT
CCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACC
TGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATG
CCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGG
TACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCC
TTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACC
TCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCC
TGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGG
TGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGG
ATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCA
TGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTA
TCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCT
GCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGA
CACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGC
CTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGG
GGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGA
TTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGG

>44419_44419_17_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000588216_length(amino acids)=1062AA_BP=598
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARD
CRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKA
CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAV
DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLL
SGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQP
REAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIA
CWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTL
ADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDK
DFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNA
TWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGIC

--------------------------------------------------------------
>44419_44419_18_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000592287_length(transcript)=3398nt_BP=1863nt
GTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGG
GGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGT
TCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGA
CGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCC
AAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAAACTGCA
TCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCGAGGGAC
CCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAGATGAAC
CCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACGAGTGCC
TGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGCTCTGCG
TGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCTCCATCG
CCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGAGGAACG
TGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTGACAGAG
CCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCAACATCT
ACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCTCCAAGC
CAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCCTGAATG
GTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACTGGGTTG
ACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCCACCCCT
TCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTTCCGATG
TCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGAGGCTGAGGCTGCAGTGG
CCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCT
CCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACC
TGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATG
CCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGG
TACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCC
TTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACC
TCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCC
TGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGG
TGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGG
ATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCA
TGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTA
TCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCT
GCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGA
CACTGCTGGAAAACACAGGTCGCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGG
TGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCG
GCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGA
AGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAAT
TCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGG

>44419_44419_18_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000545707_TNPO2_chr19_12817609_ENST00000592287_length(amino acids)=1072AA_BP=598
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPVATCRPDEFQCSDGNCIHGSRQCDREYDCKDMSDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARD
CRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCEDIDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKA
CKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWSDLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAV
DWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWTDWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLL
SGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDIINEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQP
REAEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIA
CWTLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTL
ADSVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDK
DFMIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNA
TWAIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNE

--------------------------------------------------------------
>44419_44419_19_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000356861_length(transcript)=5855nt_BP=2398nt
AGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATG
GGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAG
TTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAG
ACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGC
CAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGC
ATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCC
AGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCG
CAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCAC
TCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTC
CAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTT
AATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGAC
TGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGAC
CTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCC
GACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCC
TGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGC
CTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATC
TGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTG
GACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTA
TTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAG
ATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTC
AGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGAT
GAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCC
AACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCA
AGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCG
CCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACC
CAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGG
CTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCT
GAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCAC
TGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAG
GAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTC
TTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAAC
CAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTG
GAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAG
AAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTG
CTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAG
GACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCC
GAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATG
CAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTG
CTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGG
TGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGC
GTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTC
CACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTC
TATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTC
GCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGT
CCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTG
GGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGA
GGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCA
TAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGC
CTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGC
CTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACA
CTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTG
GGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTG
GGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCC
CCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGC
AAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGT
ACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGG
GCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTT
TCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCC
TCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACA
TTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAG
TTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCT
GATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTT
TTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCC
CTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTC
CATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACTTGTGTAGAACTTTGTTGAGTAAAGATCAGTTTCTT

>44419_44419_19_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000356861_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_20_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000425528_length(transcript)=5892nt_BP=2398nt
AGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATG
GGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAG
TTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAG
ACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGC
CAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGC
ATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCC
AGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCG
CAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCAC
TCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTC
CAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTT
AATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGAC
TGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGAC
CTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCC
GACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCC
TGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGC
CTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATC
TGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTG
GACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTA
TTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAG
ATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTC
AGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGAT
GAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCC
AACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCA
AGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCG
CCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACC
CAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGG
CTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCT
GAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCAC
TGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAG
GAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTC
TTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAAC
CAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTG
GAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAG
AAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTG
CTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAG
GACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCC
GAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATG
CAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTG
CTGGAAAACACAGGTCGCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCA
CCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATC
TGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGAT
GACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCG
CCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGA
TTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTT
CCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTG
GGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATT
ACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGAC
ACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAA
TTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGG
TGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAG
CACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAG
CTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACT
GGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGG
GCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGA
TGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCC
ATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAA
TAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTG
CAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTC
TCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCT
GCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTG
GAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGG
TCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGG
GGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCAC
AATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACC
CTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACTTGTGT

>44419_44419_20_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000425528_length(amino acids)=1250AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEK

--------------------------------------------------------------
>44419_44419_21_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000441499_length(transcript)=5862nt_BP=2398nt
AGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATG
GGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAG
TTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAG
ACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGC
CAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGC
ATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCC
AGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCG
CAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCAC
TCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTC
CAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTT
AATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGAC
TGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGAC
CTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCC
GACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCC
TGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGC
CTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATC
TGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTG
GACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTA
TTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAG
ATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTC
AGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGAT
GAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCC
AACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCA
AGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCG
CCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACC
CAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGG
CTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCT
GAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCAC
TGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAG
GAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTC
TTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAAC
CAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTG
GAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAG
AAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTG
CTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAG
GACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCC
GAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATG
CAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTG
CTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGG
TGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGC
GTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTC
CACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTC
TATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTC
GCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGT
CCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTG
GGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGA
GGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCA
TAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGC
CTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGC
CTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACA
CTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTG
GGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTG
GGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCC
CCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGC
AAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGT
ACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGG
GCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTT
TCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCC
TCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACA
TTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAG
TTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCT
GATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTT
TTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCC
CTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTC
CATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACTTGTGTAGAACTTTGTTGAGTAAAGATCAGTTTCTT

>44419_44419_21_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000441499_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_22_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000450764_length(transcript)=5383nt_BP=2398nt
AGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATG
GGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAG
TTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAG
ACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGC
CAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGC
ATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCC
AGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCG
CAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCAC
TCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTC
CAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTT
AATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGAC
TGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGAC
CTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCC
GACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCC
TGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGC
CTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATC
TGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTG
GACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTA
TTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAG
ATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTC
AGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGAT
GAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCC
AACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCA
AGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCG
CCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACC
CAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGG
CTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCT
GAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCAC
TGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAG
GAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTC
TTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAAC
CAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTG
GAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAG
AAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTG
CTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAG
GACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCC
GAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATG
CAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTG
CTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGG
TGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGC
GTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTC
CACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTC
TATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTC
GCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGT
CCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTG
GGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGA
GGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCA
TAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGC
CTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGC
CTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACA
CTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTG
GGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTG
GGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCC
CCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGC
AAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGT
ACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGG
GCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTT
TCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCC
TCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACA

>44419_44419_22_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000450764_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_23_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000588216_length(transcript)=3811nt_BP=2398nt
AGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATG
GGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAG
TTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAG
ACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGC
CAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGC
ATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCC
AGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCG
CAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCAC
TCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTC
CAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTT
AATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGAC
TGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGAC
CTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCC
GACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCC
TGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGC
CTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATC
TGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTG
GACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTA
TTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAG
ATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTC
AGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGAT
GAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCC
AACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCA
AGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCG
CCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACC
CAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGG
CTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCT
GAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCAC
TGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAG
GAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTC
TTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAAC
CAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTG
GAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAG
AAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTG
CTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAG
GACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCC
GAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATG
CAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTG
CTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGG
TGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGC
GTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTC
CACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTC

>44419_44419_23_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000588216_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_24_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000592287_length(transcript)=3933nt_BP=2398nt
AGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATG
GGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAG
TTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAG
ACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGC
CAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGC
ATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCC
AGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCG
CAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCAC
TCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTC
CAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTT
AATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGAC
TGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGAC
CTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCC
GACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCC
TGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGC
CTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATC
TGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTG
GACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTA
TTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAG
ATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTC
AGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGAT
GAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCC
AACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCA
AGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCG
CCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACC
CAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGG
CTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCT
GAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCAC
TGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAG
GAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTC
TTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAAC
CAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTG
GAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAG
AAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTG
CTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAG
GACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCC
GAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATG
CAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTG
CTGGAAAACACAGGTCGCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCA
CCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATC
TGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGAT
GACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCG
CCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGA

>44419_44419_24_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000557933_TNPO2_chr19_12817609_ENST00000592287_length(amino acids)=1250AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEK

--------------------------------------------------------------
>44419_44419_25_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000356861_length(transcript)=5839nt_BP=2382nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGTTCCAGTGCCAAGACG
GGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGACGTGCTTGTCTGTCA
CCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCCAAGTGGACTGCGACA
ACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCG
TCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACA
GCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTC
TTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTG
ATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAA
ACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCG
AGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAG
ATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACG
AGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGC
TCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCT
CCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGA
GGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTG
ACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCA
ACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCT
CCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCC
TGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACT
GGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCC
ACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTT
CCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGT
GTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCG
CCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCG
TCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCC
CTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACC
TGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGC
CACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTG
CTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAAT
ACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCC
AGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGG
TGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGG
CCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCG
AGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGG
TCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTC
TGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGA
TGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCA
TCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGA
ACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTA
TTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACC
AAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGA
TCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGA
GGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGG
CAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCA
TCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAG
GTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGG
GCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGC
ATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCG
GGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTG
TTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTC
ACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTA
CTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAG
GCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAG
GCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGA
GATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGG
TGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCT
ACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACC
CTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTG
GGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTT
TAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACC
CCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAA
AAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGG
ACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCT

>44419_44419_25_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000356861_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_26_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000425528_length(transcript)=5876nt_BP=2382nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGTTCCAGTGCCAAGACG
GGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGACGTGCTTGTCTGTCA
CCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCCAAGTGGACTGCGACA
ACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCG
TCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACA
GCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTC
TTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTG
ATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAA
ACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCG
AGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAG
ATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACG
AGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGC
TCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCT
CCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGA
GGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTG
ACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCA
ACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCT
CCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCC
TGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACT
GGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCC
ACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTT
CCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGT
GTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCG
CCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCG
TCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCC
CTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACC
TGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGC
CACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTG
CTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAAT
ACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCC
AGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGG
TGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGG
CCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCG
AGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGG
TCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTC
TGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGA
TGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGGTC
GCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGT
TCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTG
TCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGT
TTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGA
GGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGC
TGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCC
GTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTG
GGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAAT
CCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGC
ATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAG
TTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTG
GGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGG
ACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAAC
CACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTT
CCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTG
TGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACAC
AGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTC
CTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGG
TCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCAT
TTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCT
GCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGG
GCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAA
AAAAAAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGA
TGGATTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCT
CGTTTTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTT
CTCAACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGG
CTCCCGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACTTGTGTAGAACTTTGTTGAGTA

>44419_44419_26_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000425528_length(amino acids)=1250AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEK

--------------------------------------------------------------
>44419_44419_27_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000441499_length(transcript)=5846nt_BP=2382nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGTTCCAGTGCCAAGACG
GGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGACGTGCTTGTCTGTCA
CCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCCAAGTGGACTGCGACA
ACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCG
TCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACA
GCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTC
TTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTG
ATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAA
ACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCG
AGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAG
ATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACG
AGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGC
TCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCT
CCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGA
GGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTG
ACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCA
ACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCT
CCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCC
TGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACT
GGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCC
ACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTT
CCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGT
GTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCG
CCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCG
TCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCC
CTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACC
TGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGC
CACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTG
CTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAAT
ACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCC
AGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGG
TGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGG
CCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCG
AGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGG
TCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTC
TGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGA
TGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCA
TCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGA
ACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTA
TTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACC
AAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGA
TCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGA
GGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGG
CAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCA
TCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAG
GTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGG
GCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGC
ATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCG
GGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTG
TTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTC
ACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTA
CTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAG
GCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAG
GCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGA
GATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGG
TGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCT
ACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACC
CTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTG
GGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTT
TAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACC
CCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAA
AAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGG
ACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCT

>44419_44419_27_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000441499_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_28_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000450764_length(transcript)=5367nt_BP=2382nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGTTCCAGTGCCAAGACG
GGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGACGTGCTTGTCTGTCA
CCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCCAAGTGGACTGCGACA
ACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCG
TCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACA
GCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTC
TTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTG
ATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAA
ACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCG
AGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAG
ATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACG
AGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGC
TCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCT
CCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGA
GGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTG
ACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCA
ACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCT
CCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCC
TGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACT
GGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCC
ACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTT
CCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGT
GTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCG
CCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCG
TCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCC
CTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACC
TGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGC
CACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTG
CTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAAT
ACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCC
AGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGG
TGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGG
CCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCG
AGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGG
TCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTC
TGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGA
TGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCA
TCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGA
ACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTA
TTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACC
AAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGA
TCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGA
GGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGG
CAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCA
TCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAG
GTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGG
GCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGC
ATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCG
GGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTG
TTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTC
ACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTA
CTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAG
GCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAG
GCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGA
GATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGG
TGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCT
ACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACC
CTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTG

>44419_44419_28_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000450764_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_29_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000588216_length(transcript)=3795nt_BP=2382nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGTTCCAGTGCCAAGACG
GGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGACGTGCTTGTCTGTCA
CCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCCAAGTGGACTGCGACA
ACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCG
TCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACA
GCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTC
TTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTG
ATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAA
ACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCG
AGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAG
ATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACG
AGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGC
TCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCT
CCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGA
GGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTG
ACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCA
ACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCT
CCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCC
TGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACT
GGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCC
ACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTT
CCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGT
GTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCG
CCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCG
TCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCC
CTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACC
TGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGC
CACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTG
CTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAAT
ACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCC
AGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGG
TGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGG
CCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCG
AGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGG
TCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTC
TGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGA
TGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGCCA
TCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGA
ACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTA
TTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACC
AAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGA

>44419_44419_29_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000588216_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_30_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000592287_length(transcript)=3917nt_BP=2382nt
GCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGCTGCGAGCATGGGGCCCTGGGGCTGGA
AATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGAAAGAAACGAGTTCCAGTGCCAAGACG
GGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGAGTCCCAGGAGACGTGCTTGTCTGTCA
CCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAGGTGCGATGGCCAAGTGGACTGCGACA
ACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGATGGGAAGTGCATCTCTCGGCAGTTCG
TCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTGTGGTCCCGCCAGCTTCCAGTGCAACA
GCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGATGAGTGGCCGCAGCGCTGTAGGGGTC
TTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGAGTGCATCCACTCCAGCTGGCGCTGTG
ATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCCTGACGAATTCCAGTGCTCTGATGGAA
ACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGTTGGCTGCGTTAATGTGACACTCTGCG
AGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACATGGCTAGAGACTGCCGGGACTGGTCAG
ATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGTCTGCAATGACCTTAAGATCGGCTACG
AGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTGTCAGGATCCCGACACCTGCAGCCAGC
TCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCACACGAAGGCCTGCAAGGCTGTGGGCT
CCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGAGTACACCAGCCTCATCCCCAACCTGA
GGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCAGAGAATGATCTGCAGCACCCAGCTTG
ACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGGGCTGGCTGTGGACTGGATCCACAGCA
ACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAGGAAAACGTTATTCAGGGAGAACGGCT
CCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAACTCCCGCCAAGATCAAGAAAGGGGGCC
TGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCTAGATCTCCTCAGTGGCCGCCTCTACT
GGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCATCTTGGAGGATGAAAAGAGGCTGGCCC
ACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCATTTTCAGTGCCAACCGCCTCACAGGTT
CCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCTCACCCAGCCAAGAGGAGTGAACTGGT
GTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAACCCCCACTCGCCCAAGTTTACCTGCG
CCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGCAGTGGCCACCCAGGAGACATCCACCG
TCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGACACCTCCCGGCTGCCTGGGGCCACCC
CTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCCCTACCTGCCTGAGCTGATCCCGCACC
TGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCGCTATGCCCACTGGGTGGTCAGCCAGC
CACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAAGAGGGTACAGGAGGCGGCCTGCAGTG
CTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGACACCCTTGTCTTTGCCTTTGGGAAAT
ACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCACCACCTCAACCAGCCGGAATACATCC
AGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTTCCCCCTGCTGGAGTGTCTGTCATCGG
TGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCACCCTGGTGCAGAAGACACTGGCTCAGG
CCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGCACTGGATCTGCTCAGCGGCCTGGCCG
AGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCAGTGCATGCAGGACTCGATGCCTGAGG
TCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCCCTGTATCGCCGAGTTCATGCCCATTC
TGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGAAATCTGCATGCAGATGGGGGCAGAGA
TGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACCCAAGACACTGCTGGAAAACACAGGTC
GCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGT
TCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTG
TCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGT
TTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGA
GGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGC

>44419_44419_30_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558013_TNPO2_chr19_12817609_ENST00000592287_length(amino acids)=1250AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEK

--------------------------------------------------------------
>44419_44419_31_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000356861_length(transcript)=5955nt_BP=2498nt
CTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGAC
GTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGC
TGCGAGCATGGGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGA
AAGAAACGAGTTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGA
GTCCCAGGAGACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAG
GTGCGATGGCCAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGA
TGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTG
TGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGA
TGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGA
GTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCC
TGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGT
TGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACAT
GGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGT
CTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTG
TCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCA
CACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGA
GTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCA
GAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGG
GCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAG
GAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAAC
TCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCT
AGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCAT
CTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCAT
TTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCT
CACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAA
CCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGC
AGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGA
CACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCC
CTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCG
CTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAA
GAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGA
CACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCA
CCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTT
CCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCAC
CCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGC
ACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCA
GTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCC
CTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGA
AATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACC
CAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCAT
CCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAA
CCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTA
TAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCT
GGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCA
TCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCC
GTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCA
AGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGG
CTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGT
GCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAA
CCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTG
GGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCC
ACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACT
GGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTG
AAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCT
TCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGT
TTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGC
TCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAA
GGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTT
TCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTC
CATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCAC
TCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAA
AAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGA
TTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTT
TTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCA
ACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCC
CGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACTTGTGTAGAACTTTGTTGAGTAAAGA

>44419_44419_31_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000356861_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_32_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000425528_length(transcript)=5992nt_BP=2498nt
CTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGAC
GTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGC
TGCGAGCATGGGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGA
AAGAAACGAGTTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGA
GTCCCAGGAGACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAG
GTGCGATGGCCAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGA
TGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTG
TGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGA
TGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGA
GTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCC
TGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGT
TGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACAT
GGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGT
CTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTG
TCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCA
CACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGA
GTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCA
GAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGG
GCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAG
GAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAAC
TCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCT
AGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCAT
CTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCAT
TTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCT
CACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAA
CCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGC
AGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGA
CACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCC
CTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCG
CTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAA
GAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGA
CACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCA
CCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTT
CCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCAC
CCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGC
ACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCA
GTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCC
CTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGA
AATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACC
CAAGACACTGCTGGAAAACACAGGTCGCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCA
GGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTT
CCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAG
CCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGA
GCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTC
GTCGGAGGGATTACTGGGGAGTGCGCTGCATCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATC
CAGATGCCTTCCCCGTCCGTCCGTCCGTCCGTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAA
CGGGGAGGTGGGGGGGACTTCTGGTGGGCAAGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGA
GGGAGGAATTACACAGCTGACCGAATCCGGCTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACAC
TCACACGGACACACATGGCCACACGCATGTGCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGA
GACAGTAGAATTAGTGAACCCCTGAGTTAACCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCG
GAATTGGCGGTGACTGGGGAGGGCTGGGTGGGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTC
GCCCTGTCAGCACGCACATGCTTGGGACCCACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTAT
CCTAGCCTAGCTCGCAGGGTGAGAACCACTGGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTT
TGAAGACACTGGGTTGGGACCTTTTTCCTGAAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGC
AGCTTCAGGGGCAGTCCGTTTCTCTGTGCTTCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGC
GTTTAATTGATGATGACAGAGGACACAGGTTTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGT
TCCCTATTCCATCTCCCTGGGACTTCCTGCTCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAA
CCTTCCGGAATAGTCTGGGAACATGGTCAAGGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAA
CTGGGCCTTGCAGACCCCCTTAGCATTTTTTCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCT
GACTGGAGTCTCGCATCCTGGGGCCTGCTCCATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGG
GTCAGGCCCTGCATCTATTCCAAGGGGCACTCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAG
CAGGTCTCTGGAAGCCATTTGTTAAAAAAAAAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATC
CTCTGCTGGGTCTTGGGGTGTGTGGATGGATTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCT
TCAGGGAAGGGGAGCCTGGTTCTTCTCGTTTTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTG
TTTTTTGCACAATGAAGTTTCAGCTTCTCAACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTC
CCTCCTCACCCTCTTCCCCCTGCGGGCTCCCGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATT

>44419_44419_32_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000425528_length(amino acids)=1250AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEK

--------------------------------------------------------------
>44419_44419_33_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000441499_length(transcript)=5962nt_BP=2498nt
CTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGAC
GTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGC
TGCGAGCATGGGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGA
AAGAAACGAGTTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGA
GTCCCAGGAGACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAG
GTGCGATGGCCAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGA
TGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTG
TGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGA
TGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGA
GTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCC
TGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGT
TGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACAT
GGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGT
CTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTG
TCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCA
CACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGA
GTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCA
GAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGG
GCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAG
GAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAAC
TCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCT
AGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCAT
CTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCAT
TTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCT
CACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAA
CCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGC
AGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGA
CACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCC
CTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCG
CTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAA
GAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGA
CACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCA
CCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTT
CCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCAC
CCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGC
ACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCA
GTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCC
CTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGA
AATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACC
CAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCAT
CCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAA
CCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTA
TAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCT
GGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCA
TCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCC
GTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCA
AGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGG
CTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGT
GCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAA
CCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTG
GGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCC
ACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACT
GGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTG
AAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCT
TCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGT
TTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGC
TCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAA
GGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTT
TCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTC
CATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCAC
TCAGTACACATTCCATAAATTAGCTGGGTGTCCCTGCACGCCCACCCCATGAAACTCGAGCAGGTCTCTGGAAGCCATTTGTTAAAAAAA
AAAAAAAAAGTTTTAAAAATACCTTTTAATTTTCTGGTAATTCCAGTTCTTTGAAGCATCCTCTGCTGGGTCTTGGGGTGTGTGGATGGA
TTGGCTGTCTGATGGGATTGGTAACCCCTCGCTACTCAAGATGGGGGGATACAAACACCTTCAGGGAAGGGGAGCCTGGTTCTTCTCGTT
TTCCTTTTTTTTTTTTTTTTTAAAAAAAAACTATTTAATTTTTTAATTTATTTTTGGTTGTTTTTTGCACAATGAAGTTTCAGCTTCTCA
ACCTTCTCCCCTACCCAGGGCTGTGGACCCAGACTGGCCTTGAGCCACAGTCCCTCTTTCCCTCCTCACCCTCTTCCCCCTGCGGGCTCC
CGGGTCTGTCCATTTGTTACTGTGCTGTGCTGGGGATTGGCGCCGAGGTGGCGTGAGATTCCACTTGTGTAGAACTTTGTTGAGTAAAGA

>44419_44419_33_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000441499_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_34_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000450764_length(transcript)=5483nt_BP=2498nt
CTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGAC
GTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGC
TGCGAGCATGGGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGA
AAGAAACGAGTTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGA
GTCCCAGGAGACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAG
GTGCGATGGCCAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGA
TGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTG
TGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGA
TGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGA
GTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCC
TGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGT
TGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACAT
GGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGT
CTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTG
TCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCA
CACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGA
GTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCA
GAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGG
GCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAG
GAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAAC
TCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCT
AGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCAT
CTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCAT
TTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCT
CACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAA
CCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGC
AGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGA
CACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCC
CTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCG
CTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAA
GAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGA
CACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCA
CCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTT
CCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCAC
CCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGC
ACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCA
GTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCC
CTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGA
AATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACC
CAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCAT
CCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAA
CCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTA
TAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCT
GGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTCGTCGGAGGGATTACTGGGGAGTGCGCTGCA
TCCGGAAGTCGCTGTGCCCTGGTTGAGGGGGGTTAGGGAGGAGTGAGTGGGACTCAAATCCAGATGCCTTCCCCGTCCGTCCGTCCGTCC
GTCCATCCGTCCACTTGCCCTCCTGGCAGGTGGGTGGGGCCACCATGCTCATCCTACAAACGGGGAGGTGGGGGGGACTTCTGGTGGGCA
AGGGCCCCTGGGCTCTAATAGGGTCATCTCTGGCAGCCCACTTGGGCCAGCTACGTGGGAGGGAGGAATTACACAGCTGACCGAATCCGG
CTTCGGATGAGGTGAGGGAGGAGCAGGTCAGGAGGGGGGCCCTCGTAGGGACGCGTACACTCACACGGACACACATGGCCACACGCATGT
GCGGGTGCCATAACCGGCGAGGCTGGGCCAGCCGCTCCACCATTTCCCCGACTGCATGGAGACAGTAGAATTAGTGAACCCCTGAGTTAA
CCCGTAAGGCCTTCCGTGTAACCTGCATCTAGAGTTTAAGAAGCTTCTGCTGTTTTGCCGGAATTGGCGGTGACTGGGGAGGGCTGGGTG
GGTGGGGGGCCTCAGGCGGGATCTCGGGGCGGGGGGAGGAGGATGGTGACCTTGGGAGTCGCCCTGTCAGCACGCACATGCTTGGGACCC
ACTCCACACACTCCCTGCCAGCTTTGTTGCAGCCTCAGCTGGTGGTGTCTCCGTCCTTATCCTAGCCTAGCTCGCAGGGTGAGAACCACT
GGAGTGGCTGGGGCTGGCCAGAGGTCACCGTTTCTCCTTCCTGTGTGCTCCAGTGGCTTTTGAAGACACTGGGTTGGGACCTTTTTCCTG
AAGAGAGCTGGGTGTAGCCAGAGCTACTGGCACCTACCCCGAGCATCTCTCTCTGTAAGCAGCTTCAGGGGCAGTCCGTTTCTCTGTGCT
TCTGAAACCCCCTTCTCACGTTTCAGGCCCCAGTTTTAACTCAAGGCCTGGGGCAGGGGCGTTTAATTGATGATGACAGAGGACACAGGT
TTTTGCCAGCAAAAAGGAAAACCAAGGCTTGGTGGAAGGGAAAGGTGGTGTGTCCCCTGTTCCCTATTCCATCTCCCTGGGACTTCCTGC
TCATCATAGTACCCAGTGAGCCCAGAGATCCTACTAGACTGGGTCAGCAATTCTAGAGAACCTTCCGGAATAGTCTGGGAACATGGTCAA
GGTGGAAGGGGCTCCCCTAGAGAGGGTGGGGGTGTAGTTACTTCCCAGTTGGCCAGAAAACTGGGCCTTGCAGACCCCCTTAGCATTTTT
TCCCTTTTTTTCCTTCCCTGCTTTCTACTTCTTTGGGGAGCCCCTTGTGTTTTGGAGTCTGACTGGAGTCTCGCATCCTGGGGCCTGCTC
CATCCATCCCTCCTGGGCGCCAGACCCTCCATCCAAGCCCTGTGTCTTTCCATAGTCAGGGTCAGGCCCTGCATCTATTCCAAGGGGCAC

>44419_44419_34_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000450764_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_35_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000588216_length(transcript)=3911nt_BP=2498nt
CTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGAC
GTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGC
TGCGAGCATGGGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGA
AAGAAACGAGTTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGA
GTCCCAGGAGACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAG
GTGCGATGGCCAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGA
TGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTG
TGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGA
TGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGA
GTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCC
TGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGT
TGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACAT
GGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGT
CTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTG
TCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCA
CACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGA
GTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCA
GAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGG
GCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAG
GAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAAC
TCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCT
AGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCAT
CTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCAT
TTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCT
CACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAA
CCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGC
AGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGA
CACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCC
CTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCG
CTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAA
GAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGA
CACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCA
CCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTT
CCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCAC
CCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGC
ACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCA
GTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCC
CTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGA
AATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACC
CAAGACACTGCTGGAAAACACAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCAGGAGGTGGCACCCATGCTGCAGCAGTTCAT
CCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTTCCGCGGCATCTGCATGATGATCGGTGTCAA
CCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAGCCCGAAGGATGACCTTCGGGACATGTTTTA
TAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGAGCAATTCCCGCCGCTGCTCAAGGAGAGGCT

>44419_44419_35_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000588216_length(amino acids)=1240AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEKDSAFRGICMM

--------------------------------------------------------------
>44419_44419_36_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000592287_length(transcript)=4033nt_BP=2498nt
CTCTTGCAGTGAGGTGAAGACATTTGAAAATCACCCCACTGCAAACTCCTCCCCCTGCTAGAAACCTCACATTGAAATGCTGTAAATGAC
GTGGGCCCCGAGTGCAATCGCGGGAAGCCAGGGTTTCCAGCTAGGACACAGCAGGTCGTGATCCGGGTCGGGACACTGCCTGGCAGAGGC
TGCGAGCATGGGGCCCTGGGGCTGGAAATTGCGCTGGACCGTCGCCTTGCTCCTCGCCGCGGCGGGGACTGCAGTGGGCGACAGATGCGA
AAGAAACGAGTTCCAGTGCCAAGACGGGAAATGCATCTCCTACAAGTGGGTCTGCGATGGCAGCGCTGAGTGCCAGGATGGCTCTGATGA
GTCCCAGGAGACGTGCTTGTCTGTCACCTGCAAATCCGGGGACTTCAGCTGTGGGGGCCGTGTCAACCGCTGCATTCCTCAGTTCTGGAG
GTGCGATGGCCAAGTGGACTGCGACAACGGCTCAGACGAGCAAGGCTGTCCCCCCAAGACGTGCTCCCAGGACGAGTTTCGCTGCCACGA
TGGGAAGTGCATCTCTCGGCAGTTCGTCTGTGACTCAGACCGGGACTGCTTGGACGGCTCAGACGAGGCCTCCTGCCCGGTGCTCACCTG
TGGTCCCGCCAGCTTCCAGTGCAACAGCTCCACCTGCATCCCCCAGCTGTGGGCCTGCGACAACGACCCCGACTGCGAAGATGGCTCGGA
TGAGTGGCCGCAGCGCTGTAGGGGTCTTTACGTGTTCCAAGGGGACAGTAGCCCCTGCTCGGCCTTCGAGTTCCACTGCCTAAGTGGCGA
GTGCATCCACTCCAGCTGGCGCTGTGATGGTGGCCCCGACTGCAAGGACAAATCTGACGAGGAAAACTGCGCTGTGGCCACCTGTCGCCC
TGACGAATTCCAGTGCTCTGATGGAAACTGCATCCATGGCAGCCGGCAGTGTGACCGGGAATATGACTGCAAGGACATGAGCGATGAAGT
TGGCTGCGTTAATGTGACACTCTGCGAGGGACCCAACAAGTTCAAGTGTCACAGCGGCGAATGCATCACCCTGGACAAAGTCTGCAACAT
GGCTAGAGACTGCCGGGACTGGTCAGATGAACCCATCAAAGAGTGCGGGACCAACGAATGCTTGGACAACAACGGCGGCTGTTCCCACGT
CTGCAATGACCTTAAGATCGGCTACGAGTGCCTGTGCCCCGACGGCTTCCAGCTGGTGGCCCAGCGAAGATGCGAAGATATCGATGAGTG
TCAGGATCCCGACACCTGCAGCCAGCTCTGCGTGAACCTGGAGGGTGGCTACAAGTGCCAGTGTGAGGAAGGCTTCCAGCTGGACCCCCA
CACGAAGGCCTGCAAGGCTGTGGGCTCCATCGCCTACCTCTTCTTCACCAACCGGCACGAGGTCAGGAAGATGACGCTGGACCGGAGCGA
GTACACCAGCCTCATCCCCAACCTGAGGAACGTGGTCGCTCTGGACACGGAGGTGGCCAGCAATAGAATCTACTGGTCTGACCTGTCCCA
GAGAATGATCTGCAGCACCCAGCTTGACAGAGCCCACGGCGTCTCTTCCTATGACACCGTCATCAGCAGAGACATCCAGGCCCCCGACGG
GCTGGCTGTGGACTGGATCCACAGCAACATCTACTGGACCGACTCTGTCCTGGGCACTGTCTCTGTTGCGGATACCAAGGGCGTGAAGAG
GAAAACGTTATTCAGGGAGAACGGCTCCAAGCCAAGGGCCATCGTGGTGGATCCTGTTCATGGCTTCATGTACTGGACTGACTGGGGAAC
TCCCGCCAAGATCAAGAAAGGGGGCCTGAATGGTGTGGACATCTACTCGCTGGTGACTGAAAACATTCAGTGGCCCAATGGCATCACCCT
AGATCTCCTCAGTGGCCGCCTCTACTGGGTTGACTCCAAACTTCACTCCATCTCAAGCATCGATGTCAACGGGGGCAACCGGAAGACCAT
CTTGGAGGATGAAAAGAGGCTGGCCCACCCCTTCTCCTTGGCCGTCTTTGAGGACAAAGTATTTTGGACAGATATCATCAACGAAGCCAT
TTTCAGTGCCAACCGCCTCACAGGTTCCGATGTCAACTTGTTGGCTGAAAACCTACTGTCCCCAGAGGATATGGTTCTCTTCCACAACCT
CACCCAGCCAAGAGGAGTGAACTGGTGTGAGAGGACCACCCTGAGCAATGGCGGCTGCCAGTATCTGTGCCTCCCTGCCCCGCAGATCAA
CCCCCACTCGCCCAAGTTTACCTGCGCCTGCCCGGACGGCATGCTGCTGGCCAGGGACATGAGGAGCTGCCTCACAGAGGCTGAGGCTGC
AGTGGCCACCCAGGAGACATCCACCGTCAGGCTAAAGGTCAGCTCCACAGCCGTAAGGACACAGCACACAACCACCCGACCTGTTCCCGA
CACCTCCCGGCTGCCTGGGGCCACCCCTGGGCTCACCACGGTGGAGATAGTGACAATGTCTCACCAAGGCTGCATGCAGGGCATGGTGCC
CTACCTGCCTGAGCTGATCCCGCACCTGATCCAGTGCCTGTCGGATAAGAAGGCCTTGGTCCGCTCCATCGCCTGCTGGACGCTGAGCCG
CTATGCCCACTGGGTGGTCAGCCAGCCACCCGACATGCACCTCAAGCCCCTGATGACAGAGCTGCTCAAACGCATCCTGGATGGCAACAA
GAGGGTACAGGAGGCGGCCTGCAGTGCTTTTGCCACCCTGGAGGAAGAGGCCTGCACGGAGCTGGTGCCCTACCTCAGCTACATCCTGGA
CACCCTTGTCTTTGCCTTTGGGAAATACCAGCACAAGAACCTGCTCATCCTCTATGACGCCATTGGCACCCTGGCCGACTCTGTAGGCCA
CCACCTCAACCAGCCGGAATACATCCAGAAGCTGATGCCCCCACTGATCCAGAAGTGGAATGAGCTCAAGGACGAAGACAAGGACCTCTT
CCCCCTGCTGGAGTGTCTGTCATCGGTGGCCACCGCCCTGCAGAGTGGCTTCCTGCCTTACTGTGAGCCCGTCTACCAGCGCTGTGTCAC
CCTGGTGCAGAAGACACTGGCTCAGGCCATGATGTACACCCAGCACCCTGAGCAGTATGAGGCTCCCGACAAGGACTTCATGATCGTAGC
ACTGGATCTGCTCAGCGGCCTGGCCGAGGGCCTGGGTGGTCACGTGGAGCAGCTGGTGGCCCGCAGCAACATCATGACATTGCTGTTCCA
GTGCATGCAGGACTCGATGCCTGAGGTCCGGCAGAGCTCCTTTGCCCTCCTGGGAGACCTCACCAAAGCCTGCTTCATCCATGTCAAGCC
CTGTATCGCCGAGTTCATGCCCATTCTGGGCACCAACCTGAACCCAGAGTTCATCTCCGTCTGCAACAACGCCACCTGGGCCATTGGTGA
AATCTGCATGCAGATGGGGGCAGAGATGCAGCCTTATGTGCAGATGGTCCTCAACAACCTGGTGGAAATCATTAACCGACCCAACACACC
CAAGACACTGCTGGAAAACACAGGTCGCCTGACGAGTCCCTCTGCCATTCCAGCCATCACCATCGGCCGCTTGGGCTACGTGTGCCCCCA
GGAGGTGGCACCCATGCTGCAGCAGTTCATCCGGCCTTGGTGCACGTCCCTCAGGAACATCAGGGACAACGAGGAGAAGGACTCAGCCTT
CCGCGGCATCTGCATGATGATCGGTGTCAACCCGGGGGGCGTTGTGCAGGACTTTATTTTCTTCTGCGATGCTGTAGCCTCCTGGGTGAG
CCCGAAGGATGACCTTCGGGACATGTTTTATAAGATTCTCCACGGCTTCAAAGACCAAGTTGGGGAAGATAACTGGCAGCAGTTCTCTGA
GCAATTCCCGCCGCTGCTCAAGGAGAGGCTGGCGGCTTTCTATGGGGTCTAGGTGATCATGGAGACTGCCAGGTTTCTGTCTGCGTCGTC

>44419_44419_36_LDLR-TNPO2_LDLR_chr19_11234020_ENST00000558518_TNPO2_chr19_12817609_ENST00000592287_length(amino acids)=1250AA_BP=776
MAEAASMGPWGWKLRWTVALLLAAAGTAVGDRCERNEFQCQDGKCISYKWVCDGSAECQDGSDESQETCLSVTCKSGDFSCGGRVNRCIP
QFWRCDGQVDCDNGSDEQGCPPKTCSQDEFRCHDGKCISRQFVCDSDRDCLDGSDEASCPVLTCGPASFQCNSSTCIPQLWACDNDPDCE
DGSDEWPQRCRGLYVFQGDSSPCSAFEFHCLSGECIHSSWRCDGGPDCKDKSDEENCAVATCRPDEFQCSDGNCIHGSRQCDREYDCKDM
SDEVGCVNVTLCEGPNKFKCHSGECITLDKVCNMARDCRDWSDEPIKECGTNECLDNNGGCSHVCNDLKIGYECLCPDGFQLVAQRRCED
IDECQDPDTCSQLCVNLEGGYKCQCEEGFQLDPHTKACKAVGSIAYLFFTNRHEVRKMTLDRSEYTSLIPNLRNVVALDTEVASNRIYWS
DLSQRMICSTQLDRAHGVSSYDTVISRDIQAPDGLAVDWIHSNIYWTDSVLGTVSVADTKGVKRKTLFRENGSKPRAIVVDPVHGFMYWT
DWGTPAKIKKGGLNGVDIYSLVTENIQWPNGITLDLLSGRLYWVDSKLHSISSIDVNGGNRKTILEDEKRLAHPFSLAVFEDKVFWTDII
NEAIFSANRLTGSDVNLLAENLLSPEDMVLFHNLTQPRGVNWCERTTLSNGGCQYLCLPAPQINPHSPKFTCACPDGMLLARDMRSCLTE
AEAAVATQETSTVRLKVSSTAVRTQHTTTRPVPDTSRLPGATPGLTTVEIVTMSHQGCMQGMVPYLPELIPHLIQCLSDKKALVRSIACW
TLSRYAHWVVSQPPDMHLKPLMTELLKRILDGNKRVQEAACSAFATLEEEACTELVPYLSYILDTLVFAFGKYQHKNLLILYDAIGTLAD
SVGHHLNQPEYIQKLMPPLIQKWNELKDEDKDLFPLLECLSSVATALQSGFLPYCEPVYQRCVTLVQKTLAQAMMYTQHPEQYEAPDKDF
MIVALDLLSGLAEGLGGHVEQLVARSNIMTLLFQCMQDSMPEVRQSSFALLGDLTKACFIHVKPCIAEFMPILGTNLNPEFISVCNNATW
AIGEICMQMGAEMQPYVQMVLNNLVEIINRPNTPKTLLENTGRLTSPSAIPAITIGRLGYVCPQEVAPMLQQFIRPWCTSLRNIRDNEEK

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LDLR-TNPO2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LDLR-TNPO2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LDLR-TNPO2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource