FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:LGR6-RNPEP (FusionGDB2 ID:44599)

Fusion Gene Summary for LGR6-RNPEP

check button Fusion gene summary
Fusion gene informationFusion gene name: LGR6-RNPEP
Fusion gene ID: 44599
HgeneTgene
Gene symbol

LGR6

RNPEP

Gene ID

59352

6051

Gene nameleucine rich repeat containing G protein-coupled receptor 6arginyl aminopeptidase
SynonymsGPCR|VTS20631AP-B|APB
Cytomap

1q32.1

1q32.1

Type of geneprotein-codingprotein-coding
Descriptionleucine-rich repeat-containing G-protein coupled receptor 6gonadotropin receptoraminopeptidase Barginine aminopeptidase
Modification date2020031320200320
UniProtAcc

Q9HBX8

.
Ensembl transtripts involved in fusion geneENST00000367278, ENST00000255432, 
ENST00000308543, ENST00000439764, 
ENST00000471105, ENST00000367286, 
ENST00000295640, 
Fusion gene scores* DoF score4 X 2 X 3=247 X 7 X 5=245
# samples 89
** MAII scorelog2(8/24*10)=1.73696559416621
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(9/245*10)=-1.4447848426729
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LGR6 [Title/Abstract] AND RNPEP [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLGR6(202163329)-RNPEP(201965275), # samples:2
Anticipated loss of major functional domain due to fusion event.LGR6-RNPEP seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
LGR6-RNPEP seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLGR6

GO:0030177

positive regulation of Wnt signaling pathway

22615920

HgeneLGR6

GO:0030335

positive regulation of cell migration

22615920


check buttonFusion gene breakpoints across LGR6 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RNPEP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-23-1122-01ALGR6chr1

202163329

+RNPEPchr1

201965275

+
ChimerDB4OVTCGA-23-1122LGR6chr1

202163329

+RNPEPchr1

201965274

+
ChimerDB4STADTCGA-CD-8527-01ALGR6chr1

202163329

+RNPEPchr1

201958032

+


Top

Fusion Gene ORF analysis for LGR6-RNPEP

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000367278ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201965275

+
5CDS-3UTRENST00000367278ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201965274

+
5CDS-3UTRENST00000367278ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201958032

+
5CDS-intronENST00000367278ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201965275

+
5CDS-intronENST00000367278ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201965274

+
Frame-shiftENST00000367278ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201958032

+
Frame-shiftENST00000367278ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201958032

+
In-frameENST00000367278ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201965275

+
In-frameENST00000367278ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201965274

+
intron-3CDSENST00000255432ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201965275

+
intron-3CDSENST00000255432ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201965274

+
intron-3CDSENST00000255432ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201958032

+
intron-3CDSENST00000255432ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201958032

+
intron-3CDSENST00000308543ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201965275

+
intron-3CDSENST00000308543ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201965274

+
intron-3CDSENST00000308543ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201958032

+
intron-3CDSENST00000308543ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201958032

+
intron-3CDSENST00000439764ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201965275

+
intron-3CDSENST00000439764ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201965274

+
intron-3CDSENST00000439764ENST00000295640LGR6chr1

202163329

+RNPEPchr1

201958032

+
intron-3CDSENST00000439764ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201958032

+
intron-3UTRENST00000255432ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201965275

+
intron-3UTRENST00000255432ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201965274

+
intron-3UTRENST00000255432ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201958032

+
intron-3UTRENST00000308543ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201965275

+
intron-3UTRENST00000308543ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201965274

+
intron-3UTRENST00000308543ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201958032

+
intron-3UTRENST00000439764ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201965275

+
intron-3UTRENST00000439764ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201965274

+
intron-3UTRENST00000439764ENST00000471105LGR6chr1

202163329

+RNPEPchr1

201958032

+
intron-intronENST00000255432ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201965275

+
intron-intronENST00000255432ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201965274

+
intron-intronENST00000308543ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201965275

+
intron-intronENST00000308543ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201965274

+
intron-intronENST00000439764ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201965275

+
intron-intronENST00000439764ENST00000367286LGR6chr1

202163329

+RNPEPchr1

201965274

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000367278LGR6chr1202163329+ENST00000295640RNPEPchr1201965275+1948301891516475
ENST00000367278LGR6chr1202163329+ENST00000295640RNPEPchr1201965274+1948301891516475

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000367278ENST00000295640LGR6chr1202163329+RNPEPchr1201965275+0.0057294780.99427056
ENST00000367278ENST00000295640LGR6chr1202163329+RNPEPchr1201965274+0.0057294780.99427056

Top

Fusion Genomic Features for LGR6-RNPEP


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
LGR6chr1202163329+RNPEPchr1201965274+1.07E-050.9999893
LGR6chr1202163329+RNPEPchr1201965274+1.07E-050.9999893
LGR6chr1202163329+RNPEPchr1201958031+6.20E-070.9999994
LGR6chr1202163329+RNPEPchr1201965274+1.07E-050.9999893
LGR6chr1202163329+RNPEPchr1201965274+1.07E-050.9999893
LGR6chr1202163329+RNPEPchr1201958031+6.20E-070.9999994

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for LGR6-RNPEP


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr1:202163329/chr1:201965275)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LGR6

Q9HBX8

.
FUNCTION: Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor. {ECO:0000269|PubMed:21727895, ECO:0000269|PubMed:22615920}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+11826_6670968.0DomainNote=LRRNT
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+11826_6670968.0DomainNote=LRRNT
TgeneRNPEPchr1:202163329chr1:201965274ENST00000295640211298_302245651.0RegionSubstrate binding
TgeneRNPEPchr1:202163329chr1:201965275ENST00000295640211298_302245651.0RegionSubstrate binding

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118952_9550916.0Compositional biasNote=Poly-Gly
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118952_95570968.0Compositional biasNote=Poly-Gly
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116952_9550829.0Compositional biasNote=Poly-Gly
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118952_9550916.0Compositional biasNote=Poly-Gly
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118952_95570968.0Compositional biasNote=Poly-Gly
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116952_9550829.0Compositional biasNote=Poly-Gly
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+11826_660916.0DomainNote=LRRNT
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+11626_660829.0DomainNote=LRRNT
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+11826_660916.0DomainNote=LRRNT
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+11626_660829.0DomainNote=LRRNT
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118115_1360916.0RepeatNote=LRR 2
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118139_1600916.0RepeatNote=LRR 3
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118163_1860916.0RepeatNote=LRR 4
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118187_2080916.0RepeatNote=LRR 5
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118211_2320916.0RepeatNote=LRR 6
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118235_2560916.0RepeatNote=LRR 7
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118258_2790916.0RepeatNote=LRR 8
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118282_3030916.0RepeatNote=LRR 9
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118306_3280916.0RepeatNote=LRR 10
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118329_3500916.0RepeatNote=LRR 11
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118353_3740916.0RepeatNote=LRR 12
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118375_3960916.0RepeatNote=LRR 13
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118399_4200916.0RepeatNote=LRR 14
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118423_4430916.0RepeatNote=LRR 15
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+11891_1120916.0RepeatNote=LRR 1
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118115_13670968.0RepeatNote=LRR 2
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118139_16070968.0RepeatNote=LRR 3
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118163_18670968.0RepeatNote=LRR 4
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118187_20870968.0RepeatNote=LRR 5
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118211_23270968.0RepeatNote=LRR 6
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118235_25670968.0RepeatNote=LRR 7
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118258_27970968.0RepeatNote=LRR 8
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118282_30370968.0RepeatNote=LRR 9
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118306_32870968.0RepeatNote=LRR 10
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118329_35070968.0RepeatNote=LRR 11
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118353_37470968.0RepeatNote=LRR 12
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118375_39670968.0RepeatNote=LRR 13
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118399_42070968.0RepeatNote=LRR 14
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118423_44370968.0RepeatNote=LRR 15
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+11891_11270968.0RepeatNote=LRR 1
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116115_1360829.0RepeatNote=LRR 2
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116139_1600829.0RepeatNote=LRR 3
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116163_1860829.0RepeatNote=LRR 4
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116187_2080829.0RepeatNote=LRR 5
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116211_2320829.0RepeatNote=LRR 6
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116235_2560829.0RepeatNote=LRR 7
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116258_2790829.0RepeatNote=LRR 8
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116282_3030829.0RepeatNote=LRR 9
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116306_3280829.0RepeatNote=LRR 10
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116329_3500829.0RepeatNote=LRR 11
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116353_3740829.0RepeatNote=LRR 12
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116375_3960829.0RepeatNote=LRR 13
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116399_4200829.0RepeatNote=LRR 14
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116423_4430829.0RepeatNote=LRR 15
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+11691_1120829.0RepeatNote=LRR 1
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118115_1360916.0RepeatNote=LRR 2
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118139_1600916.0RepeatNote=LRR 3
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118163_1860916.0RepeatNote=LRR 4
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118187_2080916.0RepeatNote=LRR 5
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118211_2320916.0RepeatNote=LRR 6
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118235_2560916.0RepeatNote=LRR 7
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118258_2790916.0RepeatNote=LRR 8
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118282_3030916.0RepeatNote=LRR 9
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118306_3280916.0RepeatNote=LRR 10
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118329_3500916.0RepeatNote=LRR 11
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118353_3740916.0RepeatNote=LRR 12
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118375_3960916.0RepeatNote=LRR 13
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118399_4200916.0RepeatNote=LRR 14
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118423_4430916.0RepeatNote=LRR 15
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+11891_1120916.0RepeatNote=LRR 1
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118115_13670968.0RepeatNote=LRR 2
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118139_16070968.0RepeatNote=LRR 3
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118163_18670968.0RepeatNote=LRR 4
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118187_20870968.0RepeatNote=LRR 5
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118211_23270968.0RepeatNote=LRR 6
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118235_25670968.0RepeatNote=LRR 7
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118258_27970968.0RepeatNote=LRR 8
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118282_30370968.0RepeatNote=LRR 9
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118306_32870968.0RepeatNote=LRR 10
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118329_35070968.0RepeatNote=LRR 11
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118353_37470968.0RepeatNote=LRR 12
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118375_39670968.0RepeatNote=LRR 13
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118399_42070968.0RepeatNote=LRR 14
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118423_44370968.0RepeatNote=LRR 15
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+11891_11270968.0RepeatNote=LRR 1
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116115_1360829.0RepeatNote=LRR 2
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116139_1600829.0RepeatNote=LRR 3
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116163_1860829.0RepeatNote=LRR 4
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116187_2080829.0RepeatNote=LRR 5
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116211_2320829.0RepeatNote=LRR 6
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116235_2560829.0RepeatNote=LRR 7
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116258_2790829.0RepeatNote=LRR 8
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116282_3030829.0RepeatNote=LRR 9
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116306_3280829.0RepeatNote=LRR 10
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116329_3500829.0RepeatNote=LRR 11
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116353_3740829.0RepeatNote=LRR 12
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116375_3960829.0RepeatNote=LRR 13
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116399_4200829.0RepeatNote=LRR 14
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116423_4430829.0RepeatNote=LRR 15
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+11691_1120829.0RepeatNote=LRR 1
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+11825_5670916.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118589_5980916.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118620_6440916.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118666_6870916.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118709_7270916.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118749_7740916.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118796_8090916.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118831_9670916.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+11825_56770968.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118589_59870968.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118620_64470968.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118666_68770968.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118709_72770968.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118749_77470968.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118796_80970968.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118831_96770968.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+11625_5670829.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116589_5980829.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116620_6440829.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116666_6870829.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116709_7270829.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116749_7740829.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116796_8090829.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116831_9670829.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+11825_5670916.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118589_5980916.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118620_6440916.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118666_6870916.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118709_7270916.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118749_7740916.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118796_8090916.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118831_9670916.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+11825_56770968.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118589_59870968.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118620_64470968.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118666_68770968.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118709_72770968.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118749_77470968.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118796_80970968.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118831_96770968.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+11625_5670829.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116589_5980829.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116620_6440829.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116666_6870829.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116709_7270829.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116749_7740829.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116796_8090829.0Topological domainExtracellular
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116831_9670829.0Topological domainCytoplasmic
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118568_5880916.0TransmembraneHelical%3B Name%3D1
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118599_6190916.0TransmembraneHelical%3B Name%3D2
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118645_6650916.0TransmembraneHelical%3B Name%3D3
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118688_7080916.0TransmembraneHelical%3B Name%3D4
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118728_7480916.0TransmembraneHelical%3B Name%3D5
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118775_7950916.0TransmembraneHelical%3B Name%3D6
HgeneLGR6chr1:202163329chr1:201965274ENST00000255432+118810_8300916.0TransmembraneHelical%3B Name%3D7
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118568_58870968.0TransmembraneHelical%3B Name%3D1
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118599_61970968.0TransmembraneHelical%3B Name%3D2
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118645_66570968.0TransmembraneHelical%3B Name%3D3
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118688_70870968.0TransmembraneHelical%3B Name%3D4
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118728_74870968.0TransmembraneHelical%3B Name%3D5
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118775_79570968.0TransmembraneHelical%3B Name%3D6
HgeneLGR6chr1:202163329chr1:201965274ENST00000367278+118810_83070968.0TransmembraneHelical%3B Name%3D7
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116568_5880829.0TransmembraneHelical%3B Name%3D1
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116599_6190829.0TransmembraneHelical%3B Name%3D2
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116645_6650829.0TransmembraneHelical%3B Name%3D3
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116688_7080829.0TransmembraneHelical%3B Name%3D4
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116728_7480829.0TransmembraneHelical%3B Name%3D5
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116775_7950829.0TransmembraneHelical%3B Name%3D6
HgeneLGR6chr1:202163329chr1:201965274ENST00000439764+116810_8300829.0TransmembraneHelical%3B Name%3D7
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118568_5880916.0TransmembraneHelical%3B Name%3D1
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118599_6190916.0TransmembraneHelical%3B Name%3D2
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118645_6650916.0TransmembraneHelical%3B Name%3D3
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118688_7080916.0TransmembraneHelical%3B Name%3D4
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118728_7480916.0TransmembraneHelical%3B Name%3D5
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118775_7950916.0TransmembraneHelical%3B Name%3D6
HgeneLGR6chr1:202163329chr1:201965275ENST00000255432+118810_8300916.0TransmembraneHelical%3B Name%3D7
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118568_58870968.0TransmembraneHelical%3B Name%3D1
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118599_61970968.0TransmembraneHelical%3B Name%3D2
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118645_66570968.0TransmembraneHelical%3B Name%3D3
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118688_70870968.0TransmembraneHelical%3B Name%3D4
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118728_74870968.0TransmembraneHelical%3B Name%3D5
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118775_79570968.0TransmembraneHelical%3B Name%3D6
HgeneLGR6chr1:202163329chr1:201965275ENST00000367278+118810_83070968.0TransmembraneHelical%3B Name%3D7
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116568_5880829.0TransmembraneHelical%3B Name%3D1
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116599_6190829.0TransmembraneHelical%3B Name%3D2
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116645_6650829.0TransmembraneHelical%3B Name%3D3
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116688_7080829.0TransmembraneHelical%3B Name%3D4
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116728_7480829.0TransmembraneHelical%3B Name%3D5
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116775_7950829.0TransmembraneHelical%3B Name%3D6
HgeneLGR6chr1:202163329chr1:201965275ENST00000439764+116810_8300829.0TransmembraneHelical%3B Name%3D7


Top

Fusion Gene Sequence for LGR6-RNPEP


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>44599_44599_1_LGR6-RNPEP_LGR6_chr1_202163329_ENST00000367278_RNPEP_chr1_201965274_ENST00000295640_length(transcript)=1948nt_BP=301nt
GCCCGCCGGGACCGGGAGGAAGCAGCTGCGGCCATCGCGCCGTGCGTCCGCGCCCGGCCGCCAGGTGCCCCAGTAGCCCGACCGCCGAGA
TGCCCAGCCCGCCGGGGCTCCGGGCGCTATGGCTTTGCGCCGCGCTGTGCGCTTCCCGGAGGGCCGGCGGCGCCCCCCAGCCCGGCCCGG
GGCCCACCGCCTGCCCGGCCCCCTGCCACTGCCAGGAGGACGGCATCATGCTGTCTGCCGACTGCTCTGAGCTCGGGCTGTCCGCCGTTC
CGGGGGACCTGGACCCCCTGACGGCTTACCTGAGCCGGGTGTGGGCTGAGCCCTGCCTGATTGATGCTGCCAAGGAGGAGTACAACGGGG
TGATAGAAGAATTTTTGGCAACAGGAGAGAAGCTTTTTGGACCTTATGTTTGGGGAAGGTATGACTTGCTCTTCATGCCACCGTCCTTTC
CATTTGGAGGAATGGAGAACCCTTGTCTGACCTTTGTCACCCCCTGCCTGCTAGCTGGGGACCGCTCCTTGGCAGATGTCATCATCCATG
AGATCTCCCACAGTTGGTTTGGGAACCTGGTCACCAACGCCAACTGGGGTGAATTCTGGCTCAATGAAGGTTTCACCATGTACGCCCAGA
GGAGGATCTCCACCATCCTCTTTGGCGCTGCGTACACCTGCTTGGAGGCTGCAACGGGGCGGGCTCTGCTGCGTCAGCACATGGACATCA
CTGGAGAGGAAAACCCACTCAACAAGCTCCGCGTGAAGATTGAACCAGGCGTTGACCCGGACGACACCTATAATGAGACCCCCTACGAGA
AAGGTTTCTGCTTTGTTTCATACCTGGCCCACTTGGTGGGTGATCAGGATCAGTTTGACAGTTTTCTCAAGGCCTATGTGCATGAATTCA
AATTCCGAAGCATCTTAGCCGATGACTTTCTGGACTTCTACTTGGAATATTTCCCTGAGCTTAAGAAAAAGAGAGTGGATATCATTCCAG
GTTTTGAGTTTGATCGATGGCTGAATACCCCCGGCTGGCCCCCGTACCTCCCTGATCTCTCCCCTGGGGACTCACTCATGAAGCCTGCTG
AAGAGCTAGCCCAACTGTGGGCAGCCGAGGAGCTGGACATGAAGGCCATTGAAGCCGTGGCCATCTCTCCCTGGAAGACCTACCAGCTGG
TCTACTTCCTGGATAAGATCCTCCAGAAATCCCCTCTCCCTCCTGGGAATGTGAAAAAACTTGGAGACACATACCCAAGTATCTCAAATG
CCCGGAATGCAGAGCTCCGGCTGCGATGGGGCCAAATCGTCCTTAAGAACGACCACCAGGAAGATTTCTGGAAAGTGAAGGAGTTCCTGC
ATAACCAGGGGAAGCAGAAGTATACACTTCCGCTGTACCACGCAATGATGGGTGGCAGTGAGGTGGCCCAGACCCTCGCCAAGGAGACTT
TTGCATCCACCGCCTCCCAGCTCCACAGCAATGTTGTCAACTATGTCCAGCAGATCGTGGCACCCAAGGGCAGTTAGAGGCTCGTGTGCA
TGGCCCCTGCCTCTTCAGGCTCTCCAGGCTTTCAGAATAATTGTTTGTTCCCAAATTCCTGTTCCCTGATCAACTTCCTGGAGTTTATAT
CCCCTCAGGATAATCTATTCTCTAGCTTAGGTATCTGTGACTCTTGGGCCTCTGCTCTGGTGGGAACTTACTTCTCTATAGCCCACTGAG
CCCCGAGACAGAGAACCTGCCCACAGCTCTCCCCGCTACAGGCTGCAGGCACTGCAGGGCAGCGGGTATTCTCCTCCCCACCTAAGTCTC
TGGGAAGAAGTGGAGAGGACTGATGCTCTTCTTTTTTCTCTTTCTGTCCTTTTTCTTGCTGATTTTATGCAAAGGGCTGGCATTCTGATT

>44599_44599_1_LGR6-RNPEP_LGR6_chr1_202163329_ENST00000367278_RNPEP_chr1_201965274_ENST00000295640_length(amino acids)=475AA_BP=71
MPSPPGLRALWLCAALCASRRAGGAPQPGPGPTACPAPCHCQEDGIMLSADCSELGLSAVPGDLDPLTAYLSRVWAEPCLIDAAKEEYNG
VIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQ
RRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEF
KFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQL
VYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKET

--------------------------------------------------------------
>44599_44599_2_LGR6-RNPEP_LGR6_chr1_202163329_ENST00000367278_RNPEP_chr1_201965275_ENST00000295640_length(transcript)=1948nt_BP=301nt
GCCCGCCGGGACCGGGAGGAAGCAGCTGCGGCCATCGCGCCGTGCGTCCGCGCCCGGCCGCCAGGTGCCCCAGTAGCCCGACCGCCGAGA
TGCCCAGCCCGCCGGGGCTCCGGGCGCTATGGCTTTGCGCCGCGCTGTGCGCTTCCCGGAGGGCCGGCGGCGCCCCCCAGCCCGGCCCGG
GGCCCACCGCCTGCCCGGCCCCCTGCCACTGCCAGGAGGACGGCATCATGCTGTCTGCCGACTGCTCTGAGCTCGGGCTGTCCGCCGTTC
CGGGGGACCTGGACCCCCTGACGGCTTACCTGAGCCGGGTGTGGGCTGAGCCCTGCCTGATTGATGCTGCCAAGGAGGAGTACAACGGGG
TGATAGAAGAATTTTTGGCAACAGGAGAGAAGCTTTTTGGACCTTATGTTTGGGGAAGGTATGACTTGCTCTTCATGCCACCGTCCTTTC
CATTTGGAGGAATGGAGAACCCTTGTCTGACCTTTGTCACCCCCTGCCTGCTAGCTGGGGACCGCTCCTTGGCAGATGTCATCATCCATG
AGATCTCCCACAGTTGGTTTGGGAACCTGGTCACCAACGCCAACTGGGGTGAATTCTGGCTCAATGAAGGTTTCACCATGTACGCCCAGA
GGAGGATCTCCACCATCCTCTTTGGCGCTGCGTACACCTGCTTGGAGGCTGCAACGGGGCGGGCTCTGCTGCGTCAGCACATGGACATCA
CTGGAGAGGAAAACCCACTCAACAAGCTCCGCGTGAAGATTGAACCAGGCGTTGACCCGGACGACACCTATAATGAGACCCCCTACGAGA
AAGGTTTCTGCTTTGTTTCATACCTGGCCCACTTGGTGGGTGATCAGGATCAGTTTGACAGTTTTCTCAAGGCCTATGTGCATGAATTCA
AATTCCGAAGCATCTTAGCCGATGACTTTCTGGACTTCTACTTGGAATATTTCCCTGAGCTTAAGAAAAAGAGAGTGGATATCATTCCAG
GTTTTGAGTTTGATCGATGGCTGAATACCCCCGGCTGGCCCCCGTACCTCCCTGATCTCTCCCCTGGGGACTCACTCATGAAGCCTGCTG
AAGAGCTAGCCCAACTGTGGGCAGCCGAGGAGCTGGACATGAAGGCCATTGAAGCCGTGGCCATCTCTCCCTGGAAGACCTACCAGCTGG
TCTACTTCCTGGATAAGATCCTCCAGAAATCCCCTCTCCCTCCTGGGAATGTGAAAAAACTTGGAGACACATACCCAAGTATCTCAAATG
CCCGGAATGCAGAGCTCCGGCTGCGATGGGGCCAAATCGTCCTTAAGAACGACCACCAGGAAGATTTCTGGAAAGTGAAGGAGTTCCTGC
ATAACCAGGGGAAGCAGAAGTATACACTTCCGCTGTACCACGCAATGATGGGTGGCAGTGAGGTGGCCCAGACCCTCGCCAAGGAGACTT
TTGCATCCACCGCCTCCCAGCTCCACAGCAATGTTGTCAACTATGTCCAGCAGATCGTGGCACCCAAGGGCAGTTAGAGGCTCGTGTGCA
TGGCCCCTGCCTCTTCAGGCTCTCCAGGCTTTCAGAATAATTGTTTGTTCCCAAATTCCTGTTCCCTGATCAACTTCCTGGAGTTTATAT
CCCCTCAGGATAATCTATTCTCTAGCTTAGGTATCTGTGACTCTTGGGCCTCTGCTCTGGTGGGAACTTACTTCTCTATAGCCCACTGAG
CCCCGAGACAGAGAACCTGCCCACAGCTCTCCCCGCTACAGGCTGCAGGCACTGCAGGGCAGCGGGTATTCTCCTCCCCACCTAAGTCTC
TGGGAAGAAGTGGAGAGGACTGATGCTCTTCTTTTTTCTCTTTCTGTCCTTTTTCTTGCTGATTTTATGCAAAGGGCTGGCATTCTGATT

>44599_44599_2_LGR6-RNPEP_LGR6_chr1_202163329_ENST00000367278_RNPEP_chr1_201965275_ENST00000295640_length(amino acids)=475AA_BP=71
MPSPPGLRALWLCAALCASRRAGGAPQPGPGPTACPAPCHCQEDGIMLSADCSELGLSAVPGDLDPLTAYLSRVWAEPCLIDAAKEEYNG
VIEEFLATGEKLFGPYVWGRYDLLFMPPSFPFGGMENPCLTFVTPCLLAGDRSLADVIIHEISHSWFGNLVTNANWGEFWLNEGFTMYAQ
RRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLNKLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEF
KFRSILADDFLDFYLEYFPELKKKRVDIIPGFEFDRWLNTPGWPPYLPDLSPGDSLMKPAEELAQLWAAEELDMKAIEAVAISPWKTYQL
VYFLDKILQKSPLPPGNVKKLGDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHAMMGGSEVAQTLAKET

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for LGR6-RNPEP


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for LGR6-RNPEP


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for LGR6-RNPEP


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource