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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LIMD1-LARS2 (FusionGDB2 ID:44708)

Fusion Gene Summary for LIMD1-LARS2

check button Fusion gene summary
Fusion gene informationFusion gene name: LIMD1-LARS2
Fusion gene ID: 44708
HgeneTgene
Gene symbol

LIMD1

LARS2

Gene ID

8994

23395

Gene nameLIM domains containing 1leucyl-tRNA synthetase 2, mitochondrial
Synonyms-HLASA|LEURS|PRLTS4|mtLeuRS
Cytomap

3p21.31

3p21.31

Type of geneprotein-codingprotein-coding
DescriptionLIM domain-containing protein 1probable leucine--tRNA ligase, mitochondrialleucine tRNA ligase 2, mitochondrialleucine tRNA ligase 2, mitocondrialleucine translaseprobable leucyl-tRNA synthetase, mitochondrial
Modification date2020031320200313
UniProtAcc.

Q15031

Ensembl transtripts involved in fusion geneENST00000465039, ENST00000273317, 
ENST00000440097, 		ENST00000265537, 
ENST00000414984, ENST00000415258, 
ENST00000467936, 
Fusion gene scores* DoF score3 X 4 X 4=485 X 7 X 6=210
# samples 57
** MAII scorelog2(5/48*10)=0.0588936890535686
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0		log2(7/210*10)=-1.58496250072116
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LIMD1 [Title/Abstract] AND LARS2 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLARS2(45565600)-LIMD1(45677642), # samples:2
LIMD1(45707209)-LARS2(45565489), # samples:2
Anticipated loss of major functional domain due to fusion event.LIMD1-LARS2 seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
LIMD1-LARS2 seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLIMD1

GO:0001666

response to hypoxia

22286099

HgeneLIMD1

GO:0016310

phosphorylation

18439753

HgeneLIMD1

GO:0035331

negative regulation of hippo signaling

20303269

HgeneLIMD1

GO:0045892

negative regulation of transcription, DNA-templated

15542589

TgeneLARS2

GO:0006429

leucyl-tRNA aminoacylation

10684970


check buttonFusion gene breakpoints across LIMD1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across LARS2 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-78-7147-01ALIMD1chr3

45707209

-LARS2chr3

45565489

+
ChimerDB4LUADTCGA-78-7147-01ALIMD1chr3

45707209

+LARS2chr3

45565489

+
ChimerDB4LUSCTCGA-68-8251-01ALIMD1chr3

45637779

-LARS2chr3

45488383

+
ChimerDB4STADTCGA-BR-4357-01ALIMD1chr3

45637779

-LARS2chr3

45557586

+


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Fusion Gene ORF analysis for LIMD1-LARS2

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000465039ENST00000265537LIMD1chr3

45707209

+LARS2chr3

45565489

+
3UTR-3CDSENST00000465039ENST00000414984LIMD1chr3

45707209

+LARS2chr3

45565489

+
3UTR-3CDSENST00000465039ENST00000415258LIMD1chr3

45707209

+LARS2chr3

45565489

+
3UTR-3UTRENST00000465039ENST00000467936LIMD1chr3

45707209

+LARS2chr3

45565489

+
5CDS-3UTRENST00000273317ENST00000467936LIMD1chr3

45707209

+LARS2chr3

45565489

+
5CDS-3UTRENST00000273317ENST00000467936LIMD1chr3

45637779

-LARS2chr3

45557586

+
5CDS-3UTRENST00000440097ENST00000467936LIMD1chr3

45707209

+LARS2chr3

45565489

+
5CDS-3UTRENST00000440097ENST00000467936LIMD1chr3

45637779

-LARS2chr3

45557586

+
5CDS-intronENST00000273317ENST00000467936LIMD1chr3

45637779

-LARS2chr3

45488383

+
5CDS-intronENST00000440097ENST00000467936LIMD1chr3

45637779

-LARS2chr3

45488383

+
Frame-shiftENST00000273317ENST00000265537LIMD1chr3

45637779

-LARS2chr3

45488383

+
Frame-shiftENST00000273317ENST00000414984LIMD1chr3

45637779

-LARS2chr3

45488383

+
Frame-shiftENST00000273317ENST00000415258LIMD1chr3

45637779

-LARS2chr3

45488383

+
Frame-shiftENST00000440097ENST00000265537LIMD1chr3

45637779

-LARS2chr3

45488383

+
Frame-shiftENST00000440097ENST00000414984LIMD1chr3

45637779

-LARS2chr3

45488383

+
Frame-shiftENST00000440097ENST00000415258LIMD1chr3

45637779

-LARS2chr3

45488383

+
In-frameENST00000273317ENST00000265537LIMD1chr3

45707209

+LARS2chr3

45565489

+
In-frameENST00000273317ENST00000265537LIMD1chr3

45637779

-LARS2chr3

45557586

+
In-frameENST00000273317ENST00000414984LIMD1chr3

45707209

+LARS2chr3

45565489

+
In-frameENST00000273317ENST00000414984LIMD1chr3

45637779

-LARS2chr3

45557586

+
In-frameENST00000273317ENST00000415258LIMD1chr3

45707209

+LARS2chr3

45565489

+
In-frameENST00000273317ENST00000415258LIMD1chr3

45637779

-LARS2chr3

45557586

+
In-frameENST00000440097ENST00000265537LIMD1chr3

45707209

+LARS2chr3

45565489

+
In-frameENST00000440097ENST00000265537LIMD1chr3

45637779

-LARS2chr3

45557586

+
In-frameENST00000440097ENST00000414984LIMD1chr3

45707209

+LARS2chr3

45565489

+
In-frameENST00000440097ENST00000414984LIMD1chr3

45637779

-LARS2chr3

45557586

+
In-frameENST00000440097ENST00000415258LIMD1chr3

45707209

+LARS2chr3

45565489

+
In-frameENST00000440097ENST00000415258LIMD1chr3

45637779

-LARS2chr3

45557586

+
intron-3CDSENST00000465039ENST00000265537LIMD1chr3

45637779

-LARS2chr3

45488383

+
intron-3CDSENST00000465039ENST00000265537LIMD1chr3

45637779

-LARS2chr3

45557586

+
intron-3CDSENST00000465039ENST00000414984LIMD1chr3

45637779

-LARS2chr3

45488383

+
intron-3CDSENST00000465039ENST00000414984LIMD1chr3

45637779

-LARS2chr3

45557586

+
intron-3CDSENST00000465039ENST00000415258LIMD1chr3

45637779

-LARS2chr3

45488383

+
intron-3CDSENST00000465039ENST00000415258LIMD1chr3

45637779

-LARS2chr3

45557586

+
intron-3UTRENST00000465039ENST00000467936LIMD1chr3

45637779

-LARS2chr3

45557586

+
intron-intronENST00000465039ENST00000467936LIMD1chr3

45637779

-LARS2chr3

45488383

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000440097LIMD1chr345707209+ENST00000265537LARS2chr345565489+386121345562553665
ENST00000440097LIMD1chr345707209+ENST00000415258LARS2chr345565489+444521345562553665
ENST00000440097LIMD1chr345707209+ENST00000414984LARS2chr345565489+263321345562553665
ENST00000273317LIMD1chr345707209+ENST00000265537LARS2chr345565489+33261599212018665
ENST00000273317LIMD1chr345707209+ENST00000415258LARS2chr345565489+39101599212018665
ENST00000273317LIMD1chr345707209+ENST00000414984LARS2chr345565489+20981599212018665

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000440097ENST00000265537LIMD1chr345707209+LARS2chr345565489+0.0166513420.98334867
ENST00000440097ENST00000415258LIMD1chr345707209+LARS2chr345565489+0.0132601350.9867399
ENST00000440097ENST00000414984LIMD1chr345707209+LARS2chr345565489+0.0164917020.98350835
ENST00000273317ENST00000265537LIMD1chr345707209+LARS2chr345565489+0.0213131160.97868687
ENST00000273317ENST00000415258LIMD1chr345707209+LARS2chr345565489+0.0157878380.9842122
ENST00000273317ENST00000414984LIMD1chr345707209+LARS2chr345565489+0.026172250.9738278

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Fusion Genomic Features for LIMD1-LARS2


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
LIMD1chr345707209+LARS2chr345565488+0.0001046170.99989533
LIMD1chr345707209+LARS2chr345565488+0.0001046170.99989533

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for LIMD1-LARS2


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:45565600/chr3:45677642)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.LARS2

Q15031

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLIMD1chr3:45637779chr3:45557586ENST00000273317-1854_134469677.0RegionNote=Mediates nuclear export
HgeneLIMD1chr3:45707209chr3:45565489ENST00000273317+3854_134526677.0RegionNote=Mediates nuclear export
TgeneLARS2chr3:45637779chr3:45557586ENST000002655371522639_643620904.0MotifNote='KMSKS' region
TgeneLARS2chr3:45637779chr3:45557586ENST000004152581421639_643620904.0MotifNote='KMSKS' region

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLIMD1chr3:45637779chr3:45557586ENST00000273317-18470_531469677.0DomainLIM zinc-binding 1
HgeneLIMD1chr3:45637779chr3:45557586ENST00000273317-18535_595469677.0DomainLIM zinc-binding 2
HgeneLIMD1chr3:45637779chr3:45557586ENST00000273317-18595_664469677.0DomainLIM zinc-binding 3
HgeneLIMD1chr3:45707209chr3:45565489ENST00000273317+38470_531526677.0DomainLIM zinc-binding 1
HgeneLIMD1chr3:45707209chr3:45565489ENST00000273317+38535_595526677.0DomainLIM zinc-binding 2
HgeneLIMD1chr3:45707209chr3:45565489ENST00000273317+38595_664526677.0DomainLIM zinc-binding 3
HgeneLIMD1chr3:45637779chr3:45557586ENST00000273317-18472_676469677.0RegionNote=Necessary for nuclear localization
HgeneLIMD1chr3:45707209chr3:45565489ENST00000273317+38472_676526677.0RegionNote=Necessary for nuclear localization
TgeneLARS2chr3:45637779chr3:45557586ENST00000265537152292_102620904.0MotifNote='HIGH' region
TgeneLARS2chr3:45637779chr3:45557586ENST00000415258142192_102620904.0MotifNote='HIGH' region
TgeneLARS2chr3:45707209chr3:45565489ENST000002655371822639_643764904.0MotifNote='KMSKS' region
TgeneLARS2chr3:45707209chr3:45565489ENST00000265537182292_102764904.0MotifNote='HIGH' region
TgeneLARS2chr3:45707209chr3:45565489ENST000004152581721639_643764904.0MotifNote='KMSKS' region
TgeneLARS2chr3:45707209chr3:45565489ENST00000415258172192_102764904.0MotifNote='HIGH' region


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Fusion Gene Sequence for LIMD1-LARS2


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>44708_44708_1_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000273317_LARS2_chr3_45565489_ENST00000265537_length(transcript)=3326nt_BP=1599nt
GCCCGGACACCTGTCTGCAGCATGGATAAGTATGACGACCTGGGCCTGGAGGCCAGTAAATTCATCGAGGACCTGAACATGTATGAGGCC
TCTAAGGATGGGCTCTTCCGAGTGGACAAGGGTGCAGGCAACAACCCCGAGTTTGAGGAAACTCGCAGGGTGTTCGCCACCAAGATGGCC
AAAATCCACCTCCAGCAGCAGCAGCAGCAGCTCCTGCAGGAGGAGACTCTGCCCAGGGGGAGTAGAGGCCCTGTCAATGGAGGGGGCCGC
CTGGGCCCACAGGCCCGTTGGGAAGTTGTGGGCAGCAAGCTGACTGTGGATGGTGCTGCCAAGCCTCCTCTTGCTGCCTCGACAGGGGCA
CCTGGGGCAGTCACCACCCTCGCTGCTGGGCAGCCCCCGTACCCACCGCAGGAGCAGAGATCCAGGCCATACCTGCATGGCACGAGGCAT
GGCAGCCAGGACTGTGGTTCCAGGGAGAGCCTGGCGACTTCTGAGATGTCTGCTTTCCACCAGCCAGGCCCCTGTGAGGATCCTTCCTGC
CTCACTCATGGAGACTATTATGACAACCTCTCCTTGGCAAGCCCAAAGTGGGGTGACAAACCAGGAGTGTCCCCCAGCATCGGCCTGAGT
GTAGGGAGTGGGTGGCCTAGCTCCCCGGGGAGTGACCCACCACTGCCCAAACCCTGCGGGGACCATCCCCTAAATCACCGACAGCTCTCC
CTGAGCTCCAGCAGGTCTTCTGAGGGTAGCCTCGGTGGTCAGAATAGTGGCATTGGTGGCCGCAGCAGCGAGAAGCCAACAGGCCTTTGG
TCCACTGCCTCCTCCCAGCGGGTGAGCCCTGGCCTGCCTTCCCCAAACTTGGAGAACGGAGCACCAGCTGTGGGGCCTGTTCAGCCCAGG
ACCCCTTCTGTGTCAGCACCCTTGGCCCTGAGCTGCCCCAGGCAAGGAGGTCTTCCAAGATCAAACTCGGGGCTGGGGGGTGAGGTTTCA
GGTGTGATGTCCAAACCCAATGTGGACCCCCAACCCTGGTTCCAGGATGGGCCCAAATCTTACCTTTCCAGTTCTGCCCCGTCATCCTCG
CCAGCTGGTCTGGACGGTTCACAGCAGGGTGCGGTCCCTGGGCTGGGGCCGAAGCCTGGCTGCACAGACCTTGGCACTGGTCCCAAGCTC
AGCCCCACCAGTCTTGTCCATCCAGTGATGTCCACCCTGCCTGAGTTATCTTGTAAAGAGGGTCCCCTGGGCTGGTCTTCTGATGGTAGC
CTGGGATCTGTGCTCCTGGACAGCCCCAGCTCCCCTAGGGTAAGGCTGCCCTGCCAGCCCCTCGTCCCAGGTCCTGAGCTGAGACCCTCT
GCTGCTGAGTTGAAATTAGAAGCCCTCACCCAACGTCTGGAGCGAGAGATGGATGCTCACCCGAAGGCTGATTACTTTGGAGCCTGTGTG
AAATGCAGCAAAGGGGTGTTTGGGGCTGGCCAGGCCTGTCAGGCCATGGGGAACCTCTACCATGACACATGCTTCACCTGTGCAGCTTGC
AGCCGGAAGCTGAGAGGAAAAGCCTTTTATTTTGTCAACGGCAAAGTGTTTTGTGAAGAAGACTTCCTGCAAGCCTCTCAGAGCGTCATT
CTCCACAGCCCCGAGTTTGAGGATGCTTTGTGTGCCCTGATGGTAATGGCTGCTCCACTGGCCCCTCATGTAACCTCAGAGATCTGGGCA
GGCCTGGCGCTGGTGCCGAGGAAGCTCTGTGCCCACTACACTTGGGATGCCAGTGTGCTGCTCCAGGCATGGCCTGCTGTGGACCCGGAG
TTCCTGCAGCAGCCTGAGGTTGTCCAGATGGCAGTTCTGATCAACAATAAAGCTTGTGGCAAAATTCCTGTGCCCCAACAAGTTGCCCGG
GACCAGGACAAAGTCCACGAATTTGTTCTTCAAAGCGAGCTGGGTGTCAGGCTTTTGCAAGGACGAAGCATCAAGAAGTCCTTCCTTTCC
CCGAGAACTGCCCTCATCAACTTCCTGGTGCAAGATTGACAGCCAGGAGGCTGCAGCTACCACGAGGGCCTCTGAGGAACCTCCTTCCAG
GCCTGGGATGAGGGGGCGATGTCTGCTGGCCCAGGGGAAGGGAAAAGACAAATGTCTTGACTGTTGACCTCGGTCCTGTGGCAGACTGCA
GTCAACAGTGTGCCTCTGTAGTGTGGCCTGGTGCTGGGGTGAAGGTGAGCTGGGCAAAGGAGAAATATGAGCTACTGAGGAGGGGGTTGG
ACATCCTGCCCCTCACCCCCCACCCACACTGCAGGTAGAGGAGGCCATCTGATCCCATGGGAAGCCATCAGAGACACTGCTGGTGGGAGC
AGGAAGGAGCAGTGCCCCTCGAGCAGCCAGGAAGCCTGCGGATCTGGGAAATGGCTCTGCCTTAGGCACTTCTCGGGAATTTGAGGCCAG
CCTGAGGAACTGCAGGACTCAGGTGCAATGTGCCAGCCACTTGGAACTGCTAACTGAGCCTCCAGATGGTAGTGAATGGTCTCTTTGCCT
TCAGGCTGGATGAGGAAGTCATTTAGGAAATGTTCAAATAACCAATATGTGGAAATGGACACAGGGATCTTCTGAAGTTGCTTTGAATCA
AAAGGCAGGCAGTGCTGGTTCCTCTGCCTGTGTCCCCACCACTCCCCAGCTCTGTCATGCAGGCCTGTCCTCCCCAACCCCAGCTGGATG
TGCCTCCCAGGCCTGCTGTGGTTCTGACACACAGGATCCCAGGCAAGGCACCACTTCCTCACATGAATGAGGAGCAGCAAGTCATAACCA
CTCCCTTGGGTATACAATTTGCTGTGTAGTGAAGTGGAACCAGGCTCAGGCTGCTGGTCCCAACCTCAGAGCCCCACCGCAGCCCAGTAG
GGATGCAGCACGCCCCAGAGGGCTCATGTGGGCCCCAGATGGCAATGCCACCATTGTTGATGTGACTCCAGAGCCAGTTATTAGGAAGAG
CAAGCTCACCACAGAGGAGTGGAACTGAGGCCCCCCAGATGTTGCCTCCGGTGTCCAAGCCACAGCGGTCTGGCTGTTGGGAAGATGGCC
AGGAATGGACTCATACCATTGGCACATTAGGCTAATCCTGGTTTTATGTGAAGTCAGCAATTAAGTGTTCCCACTAGAACTGACCTAAGC
CACTGATTAATATTTAATGAGGGAAGGTAGGGGAGAATCTAGCCATTTTATAATGCCAGAAATCTATATATGTTATCTGATGCCATTTTT

>44708_44708_1_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000273317_LARS2_chr3_45565489_ENST00000265537_length(amino acids)=665AA_BP=526
MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQLLQEETLPRGSRGPVNGGGRLGPQARW
EVVGSKLTVDGAAKPPLAASTGAPGAVTTLAAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGPCEDPSCLTHGDYY
DNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNHRQLSLSSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQR
VSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGS
QQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLE
ALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLQASQSVILHSPEFE
DALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHE

--------------------------------------------------------------
>44708_44708_2_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000273317_LARS2_chr3_45565489_ENST00000414984_length(transcript)=2098nt_BP=1599nt
GCCCGGACACCTGTCTGCAGCATGGATAAGTATGACGACCTGGGCCTGGAGGCCAGTAAATTCATCGAGGACCTGAACATGTATGAGGCC
TCTAAGGATGGGCTCTTCCGAGTGGACAAGGGTGCAGGCAACAACCCCGAGTTTGAGGAAACTCGCAGGGTGTTCGCCACCAAGATGGCC
AAAATCCACCTCCAGCAGCAGCAGCAGCAGCTCCTGCAGGAGGAGACTCTGCCCAGGGGGAGTAGAGGCCCTGTCAATGGAGGGGGCCGC
CTGGGCCCACAGGCCCGTTGGGAAGTTGTGGGCAGCAAGCTGACTGTGGATGGTGCTGCCAAGCCTCCTCTTGCTGCCTCGACAGGGGCA
CCTGGGGCAGTCACCACCCTCGCTGCTGGGCAGCCCCCGTACCCACCGCAGGAGCAGAGATCCAGGCCATACCTGCATGGCACGAGGCAT
GGCAGCCAGGACTGTGGTTCCAGGGAGAGCCTGGCGACTTCTGAGATGTCTGCTTTCCACCAGCCAGGCCCCTGTGAGGATCCTTCCTGC
CTCACTCATGGAGACTATTATGACAACCTCTCCTTGGCAAGCCCAAAGTGGGGTGACAAACCAGGAGTGTCCCCCAGCATCGGCCTGAGT
GTAGGGAGTGGGTGGCCTAGCTCCCCGGGGAGTGACCCACCACTGCCCAAACCCTGCGGGGACCATCCCCTAAATCACCGACAGCTCTCC
CTGAGCTCCAGCAGGTCTTCTGAGGGTAGCCTCGGTGGTCAGAATAGTGGCATTGGTGGCCGCAGCAGCGAGAAGCCAACAGGCCTTTGG
TCCACTGCCTCCTCCCAGCGGGTGAGCCCTGGCCTGCCTTCCCCAAACTTGGAGAACGGAGCACCAGCTGTGGGGCCTGTTCAGCCCAGG
ACCCCTTCTGTGTCAGCACCCTTGGCCCTGAGCTGCCCCAGGCAAGGAGGTCTTCCAAGATCAAACTCGGGGCTGGGGGGTGAGGTTTCA
GGTGTGATGTCCAAACCCAATGTGGACCCCCAACCCTGGTTCCAGGATGGGCCCAAATCTTACCTTTCCAGTTCTGCCCCGTCATCCTCG
CCAGCTGGTCTGGACGGTTCACAGCAGGGTGCGGTCCCTGGGCTGGGGCCGAAGCCTGGCTGCACAGACCTTGGCACTGGTCCCAAGCTC
AGCCCCACCAGTCTTGTCCATCCAGTGATGTCCACCCTGCCTGAGTTATCTTGTAAAGAGGGTCCCCTGGGCTGGTCTTCTGATGGTAGC
CTGGGATCTGTGCTCCTGGACAGCCCCAGCTCCCCTAGGGTAAGGCTGCCCTGCCAGCCCCTCGTCCCAGGTCCTGAGCTGAGACCCTCT
GCTGCTGAGTTGAAATTAGAAGCCCTCACCCAACGTCTGGAGCGAGAGATGGATGCTCACCCGAAGGCTGATTACTTTGGAGCCTGTGTG
AAATGCAGCAAAGGGGTGTTTGGGGCTGGCCAGGCCTGTCAGGCCATGGGGAACCTCTACCATGACACATGCTTCACCTGTGCAGCTTGC
AGCCGGAAGCTGAGAGGAAAAGCCTTTTATTTTGTCAACGGCAAAGTGTTTTGTGAAGAAGACTTCCTGCAAGCCTCTCAGAGCGTCATT
CTCCACAGCCCCGAGTTTGAGGATGCTTTGTGTGCCCTGATGGTAATGGCTGCTCCACTGGCCCCTCATGTAACCTCAGAGATCTGGGCA
GGCCTGGCGCTGGTGCCGAGGAAGCTCTGTGCCCACTACACTTGGGATGCCAGTGTGCTGCTCCAGGCATGGCCTGCTGTGGACCCGGAG
TTCCTGCAGCAGCCTGAGGTTGTCCAGATGGCAGTTCTGATCAACAATAAAGCTTGTGGCAAAATTCCTGTGCCCCAACAAGTTGCCCGG
GACCAGGACAAAGTCCACGAATTTGTTCTTCAAAGCGAGCTGGGTGTCAGGCTTTTGCAAGGACGAAGCATCAAGAAGTCCTTCCTTTCC
CCGAGAACTGCCCTCATCAACTTCCTGGTGCAAGATTGACAGCCAGGAGGCTGCAGCTACCACGAGGGCCTCTGAGGAACCTCCTTCCAG

>44708_44708_2_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000273317_LARS2_chr3_45565489_ENST00000414984_length(amino acids)=665AA_BP=526
MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQLLQEETLPRGSRGPVNGGGRLGPQARW
EVVGSKLTVDGAAKPPLAASTGAPGAVTTLAAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGPCEDPSCLTHGDYY
DNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNHRQLSLSSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQR
VSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGS
QQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLE
ALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLQASQSVILHSPEFE
DALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHE

--------------------------------------------------------------
>44708_44708_3_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000273317_LARS2_chr3_45565489_ENST00000415258_length(transcript)=3910nt_BP=1599nt
GCCCGGACACCTGTCTGCAGCATGGATAAGTATGACGACCTGGGCCTGGAGGCCAGTAAATTCATCGAGGACCTGAACATGTATGAGGCC
TCTAAGGATGGGCTCTTCCGAGTGGACAAGGGTGCAGGCAACAACCCCGAGTTTGAGGAAACTCGCAGGGTGTTCGCCACCAAGATGGCC
AAAATCCACCTCCAGCAGCAGCAGCAGCAGCTCCTGCAGGAGGAGACTCTGCCCAGGGGGAGTAGAGGCCCTGTCAATGGAGGGGGCCGC
CTGGGCCCACAGGCCCGTTGGGAAGTTGTGGGCAGCAAGCTGACTGTGGATGGTGCTGCCAAGCCTCCTCTTGCTGCCTCGACAGGGGCA
CCTGGGGCAGTCACCACCCTCGCTGCTGGGCAGCCCCCGTACCCACCGCAGGAGCAGAGATCCAGGCCATACCTGCATGGCACGAGGCAT
GGCAGCCAGGACTGTGGTTCCAGGGAGAGCCTGGCGACTTCTGAGATGTCTGCTTTCCACCAGCCAGGCCCCTGTGAGGATCCTTCCTGC
CTCACTCATGGAGACTATTATGACAACCTCTCCTTGGCAAGCCCAAAGTGGGGTGACAAACCAGGAGTGTCCCCCAGCATCGGCCTGAGT
GTAGGGAGTGGGTGGCCTAGCTCCCCGGGGAGTGACCCACCACTGCCCAAACCCTGCGGGGACCATCCCCTAAATCACCGACAGCTCTCC
CTGAGCTCCAGCAGGTCTTCTGAGGGTAGCCTCGGTGGTCAGAATAGTGGCATTGGTGGCCGCAGCAGCGAGAAGCCAACAGGCCTTTGG
TCCACTGCCTCCTCCCAGCGGGTGAGCCCTGGCCTGCCTTCCCCAAACTTGGAGAACGGAGCACCAGCTGTGGGGCCTGTTCAGCCCAGG
ACCCCTTCTGTGTCAGCACCCTTGGCCCTGAGCTGCCCCAGGCAAGGAGGTCTTCCAAGATCAAACTCGGGGCTGGGGGGTGAGGTTTCA
GGTGTGATGTCCAAACCCAATGTGGACCCCCAACCCTGGTTCCAGGATGGGCCCAAATCTTACCTTTCCAGTTCTGCCCCGTCATCCTCG
CCAGCTGGTCTGGACGGTTCACAGCAGGGTGCGGTCCCTGGGCTGGGGCCGAAGCCTGGCTGCACAGACCTTGGCACTGGTCCCAAGCTC
AGCCCCACCAGTCTTGTCCATCCAGTGATGTCCACCCTGCCTGAGTTATCTTGTAAAGAGGGTCCCCTGGGCTGGTCTTCTGATGGTAGC
CTGGGATCTGTGCTCCTGGACAGCCCCAGCTCCCCTAGGGTAAGGCTGCCCTGCCAGCCCCTCGTCCCAGGTCCTGAGCTGAGACCCTCT
GCTGCTGAGTTGAAATTAGAAGCCCTCACCCAACGTCTGGAGCGAGAGATGGATGCTCACCCGAAGGCTGATTACTTTGGAGCCTGTGTG
AAATGCAGCAAAGGGGTGTTTGGGGCTGGCCAGGCCTGTCAGGCCATGGGGAACCTCTACCATGACACATGCTTCACCTGTGCAGCTTGC
AGCCGGAAGCTGAGAGGAAAAGCCTTTTATTTTGTCAACGGCAAAGTGTTTTGTGAAGAAGACTTCCTGCAAGCCTCTCAGAGCGTCATT
CTCCACAGCCCCGAGTTTGAGGATGCTTTGTGTGCCCTGATGGTAATGGCTGCTCCACTGGCCCCTCATGTAACCTCAGAGATCTGGGCA
GGCCTGGCGCTGGTGCCGAGGAAGCTCTGTGCCCACTACACTTGGGATGCCAGTGTGCTGCTCCAGGCATGGCCTGCTGTGGACCCGGAG
TTCCTGCAGCAGCCTGAGGTTGTCCAGATGGCAGTTCTGATCAACAATAAAGCTTGTGGCAAAATTCCTGTGCCCCAACAAGTTGCCCGG
GACCAGGACAAAGTCCACGAATTTGTTCTTCAAAGCGAGCTGGGTGTCAGGCTTTTGCAAGGACGAAGCATCAAGAAGTCCTTCCTTTCC
CCGAGAACTGCCCTCATCAACTTCCTGGTGCAAGATTGACAGCCAGGAGGCTGCAGCTACCACGAGGGCCTCTGAGGAACCTCCTTCCAG
GCCTGGGATGAGGGGGCGATGTCTGCTGGCCCAGGGGAAGGGAAAAGACAAATGTCTTGACTGTTGACCTCGGTCCTGTGGCAGACTGCA
GTCAACAGTGTGCCTCTGTAGTGTGGCCTGGTGCTGGGGTGAAGGTGAGCTGGGCAAAGGAGAAATATGAGCTACTGAGGAGGGGGTTGG
ACATCCTGCCCCTCACCCCCCACCCACACTGCAGGTAGAGGAGGCCATCTGATCCCATGGGAAGCCATCAGAGACACTGCTGGTGGGAGC
AGGAAGGAGCAGTGCCCCTCGAGCAGCCAGGAAGCCTGCGGATCTGGGAAATGGCTCTGCCTTAGGCACTTCTCGGGAATTTGAGGCCAG
CCTGAGGAACTGCAGGACTCAGGTGCAATGTGCCAGCCACTTGGAACTGCTAACTGAGCCTCCAGATGGTAGTGAATGGTCTCTTTGCCT
TCAGGCTGGATGAGGAAGTCATTTAGGAAATGTTCAAATAACCAATATGTGGAAATGGACACAGGGATCTTCTGAAGTTGCTTTGAATCA
AAAGGCAGGCAGTGCTGGTTCCTCTGCCTGTGTCCCCACCACTCCCCAGCTCTGTCATGCAGGCCTGTCCTCCCCAACCCCAGCTGGATG
TGCCTCCCAGGCCTGCTGTGGTTCTGACACACAGGATCCCAGGCAAGGCACCACTTCCTCACATGAATGAGGAGCAGCAAGTCATAACCA
CTCCCTTGGGTATACAATTTGCTGTGTAGTGAAGTGGAACCAGGCTCAGGCTGCTGGTCCCAACCTCAGAGCCCCACCGCAGCCCAGTAG
GGATGCAGCACGCCCCAGAGGGCTCATGTGGGCCCCAGATGGCAATGCCACCATTGTTGATGTGACTCCAGAGCCAGTTATTAGGAAGAG
CAAGCTCACCACAGAGGAGTGGAACTGAGGCCCCCCAGATGTTGCCTCCGGTGTCCAAGCCACAGCGGTCTGGCTGTTGGGAAGATGGCC
AGGAATGGACTCATACCATTGGCACATTAGGCTAATCCTGGTTTTATGTGAAGTCAGCAATTAAGTGTTCCCACTAGAACTGACCTAAGC
CACTGATTAATATTTAATGAGGGAAGGTAGGGGAGAATCTAGCCATTTTATAATGCCAGAAATCTATATATGTTATCTGATGCCATTTTT
CTGAAGTAGCCTCACATGTGGTCCCCCTGCAGTTCAGCAGTTAACAGATGACTTTTTTAGTGTAATAAAATGTTTATCATCTATGACTTC
AGGACATATGTGTGATCCTGGAATACACCATATTCCAATTTCAGAGTTAATTACAAACAGATTGAGGTATTCCATCATCATCGGAAGCAT
TGGCTGTGTGTCTGACTCCACATGGAATGCTATAAAGTGGGATACATGTGGTTCTTCTTGTTCCAGAACTTACAGTCCATGGTAGACAAC
ACTGATACAGGCAAACTAGCAACAGCAATTAAGTCACTGGTTCTCAGACTTAATACTCTGCCTGGTCCTCATGCCCAGATATTCCAATTT
AATTGGTCCATGGTGTGGCTTGAACACCAGGAATCTTTAAAACTCCACAAGTGATTCTAATGGGCAGCAAAGTTTGAGAATCACTGGACA
CATTGATGCACTTGAGCCATCATTTCTATCTAGTTCTTCCTCTTCCTAATCTTCAGGTTAGCGGGGATAAGTTTGGTCCAGGACCAAGAG
TTGGACCAAAAGGGAAGACAGGGGCCAGAAGTCTAGAGTGCTAGAGCCGACTTGAATGTACTCAGTCTCATTGCACATGGCAGTGAATAT

>44708_44708_3_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000273317_LARS2_chr3_45565489_ENST00000415258_length(amino acids)=665AA_BP=526
MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQLLQEETLPRGSRGPVNGGGRLGPQARW
EVVGSKLTVDGAAKPPLAASTGAPGAVTTLAAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGPCEDPSCLTHGDYY
DNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNHRQLSLSSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQR
VSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGS
QQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLE
ALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLQASQSVILHSPEFE
DALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHE

--------------------------------------------------------------
>44708_44708_4_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000440097_LARS2_chr3_45565489_ENST00000265537_length(transcript)=3861nt_BP=2134nt
GCAGCGGAGGACCCAGCGCCTGGAACGTACCTGCGCCTCAGCCGCCGCGCGTTTGCTCCGGCCCGACTCGCGGCCTCGGCGCCCTCCCGG
CCGATTCAGCTTCACCCGGCCCAGTCGGCTGCTGCCTTGCTGTGAGTTTCCGTGTTTGGTTGCCTAAGGAGGATGTGATTTTACTTTTTT
GCTGTTTTCTTTTTCCTTTTATAATTTGAAGAGGAGAAAAGAACTCCGCTGAGCAGGCCCGGGACGGCGAAGTGCCACCAGCTACCCCAA
CAAGGACGTCTCCAGGGGAAAGGGAGTTGGAAGCAAACTTGGTCCAGCTGGCGTTGAGGTCTCAACTTCGGCTGGACTCTTAAATCCTGG
GGTCATGCCCTTCACGCTAGGCAGGTGGAAGTCTTTACTTGTACTGGGCCGGACTTGAGCCCCGACCCTTCGCCAGCATCTCCCCGCTGC
CCTCAACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACGGCACCTGGGCTAGGCCCG
GACACCTGTCTGCAGCATGGATAAGTATGACGACCTGGGCCTGGAGGCCAGTAAATTCATCGAGGACCTGAACATGTATGAGGCCTCTAA
GGATGGGCTCTTCCGAGTGGACAAGGGTGCAGGCAACAACCCCGAGTTTGAGGAAACTCGCAGGGTGTTCGCCACCAAGATGGCCAAAAT
CCACCTCCAGCAGCAGCAGCAGCAGCTCCTGCAGGAGGAGACTCTGCCCAGGGGGAGTAGAGGCCCTGTCAATGGAGGGGGCCGCCTGGG
CCCACAGGCCCGTTGGGAAGTTGTGGGCAGCAAGCTGACTGTGGATGGTGCTGCCAAGCCTCCTCTTGCTGCCTCGACAGGGGCACCTGG
GGCAGTCACCACCCTCGCTGCTGGGCAGCCCCCGTACCCACCGCAGGAGCAGAGATCCAGGCCATACCTGCATGGCACGAGGCATGGCAG
CCAGGACTGTGGTTCCAGGGAGAGCCTGGCGACTTCTGAGATGTCTGCTTTCCACCAGCCAGGCCCCTGTGAGGATCCTTCCTGCCTCAC
TCATGGAGACTATTATGACAACCTCTCCTTGGCAAGCCCAAAGTGGGGTGACAAACCAGGAGTGTCCCCCAGCATCGGCCTGAGTGTAGG
GAGTGGGTGGCCTAGCTCCCCGGGGAGTGACCCACCACTGCCCAAACCCTGCGGGGACCATCCCCTAAATCACCGACAGCTCTCCCTGAG
CTCCAGCAGGTCTTCTGAGGGTAGCCTCGGTGGTCAGAATAGTGGCATTGGTGGCCGCAGCAGCGAGAAGCCAACAGGCCTTTGGTCCAC
TGCCTCCTCCCAGCGGGTGAGCCCTGGCCTGCCTTCCCCAAACTTGGAGAACGGAGCACCAGCTGTGGGGCCTGTTCAGCCCAGGACCCC
TTCTGTGTCAGCACCCTTGGCCCTGAGCTGCCCCAGGCAAGGAGGTCTTCCAAGATCAAACTCGGGGCTGGGGGGTGAGGTTTCAGGTGT
GATGTCCAAACCCAATGTGGACCCCCAACCCTGGTTCCAGGATGGGCCCAAATCTTACCTTTCCAGTTCTGCCCCGTCATCCTCGCCAGC
TGGTCTGGACGGTTCACAGCAGGGTGCGGTCCCTGGGCTGGGGCCGAAGCCTGGCTGCACAGACCTTGGCACTGGTCCCAAGCTCAGCCC
CACCAGTCTTGTCCATCCAGTGATGTCCACCCTGCCTGAGTTATCTTGTAAAGAGGGTCCCCTGGGCTGGTCTTCTGATGGTAGCCTGGG
ATCTGTGCTCCTGGACAGCCCCAGCTCCCCTAGGGTAAGGCTGCCCTGCCAGCCCCTCGTCCCAGGTCCTGAGCTGAGACCCTCTGCTGC
TGAGTTGAAATTAGAAGCCCTCACCCAACGTCTGGAGCGAGAGATGGATGCTCACCCGAAGGCTGATTACTTTGGAGCCTGTGTGAAATG
CAGCAAAGGGGTGTTTGGGGCTGGCCAGGCCTGTCAGGCCATGGGGAACCTCTACCATGACACATGCTTCACCTGTGCAGCTTGCAGCCG
GAAGCTGAGAGGAAAAGCCTTTTATTTTGTCAACGGCAAAGTGTTTTGTGAAGAAGACTTCCTGCAAGCCTCTCAGAGCGTCATTCTCCA
CAGCCCCGAGTTTGAGGATGCTTTGTGTGCCCTGATGGTAATGGCTGCTCCACTGGCCCCTCATGTAACCTCAGAGATCTGGGCAGGCCT
GGCGCTGGTGCCGAGGAAGCTCTGTGCCCACTACACTTGGGATGCCAGTGTGCTGCTCCAGGCATGGCCTGCTGTGGACCCGGAGTTCCT
GCAGCAGCCTGAGGTTGTCCAGATGGCAGTTCTGATCAACAATAAAGCTTGTGGCAAAATTCCTGTGCCCCAACAAGTTGCCCGGGACCA
GGACAAAGTCCACGAATTTGTTCTTCAAAGCGAGCTGGGTGTCAGGCTTTTGCAAGGACGAAGCATCAAGAAGTCCTTCCTTTCCCCGAG
AACTGCCCTCATCAACTTCCTGGTGCAAGATTGACAGCCAGGAGGCTGCAGCTACCACGAGGGCCTCTGAGGAACCTCCTTCCAGGCCTG
GGATGAGGGGGCGATGTCTGCTGGCCCAGGGGAAGGGAAAAGACAAATGTCTTGACTGTTGACCTCGGTCCTGTGGCAGACTGCAGTCAA
CAGTGTGCCTCTGTAGTGTGGCCTGGTGCTGGGGTGAAGGTGAGCTGGGCAAAGGAGAAATATGAGCTACTGAGGAGGGGGTTGGACATC
CTGCCCCTCACCCCCCACCCACACTGCAGGTAGAGGAGGCCATCTGATCCCATGGGAAGCCATCAGAGACACTGCTGGTGGGAGCAGGAA
GGAGCAGTGCCCCTCGAGCAGCCAGGAAGCCTGCGGATCTGGGAAATGGCTCTGCCTTAGGCACTTCTCGGGAATTTGAGGCCAGCCTGA
GGAACTGCAGGACTCAGGTGCAATGTGCCAGCCACTTGGAACTGCTAACTGAGCCTCCAGATGGTAGTGAATGGTCTCTTTGCCTTCAGG
CTGGATGAGGAAGTCATTTAGGAAATGTTCAAATAACCAATATGTGGAAATGGACACAGGGATCTTCTGAAGTTGCTTTGAATCAAAAGG
CAGGCAGTGCTGGTTCCTCTGCCTGTGTCCCCACCACTCCCCAGCTCTGTCATGCAGGCCTGTCCTCCCCAACCCCAGCTGGATGTGCCT
CCCAGGCCTGCTGTGGTTCTGACACACAGGATCCCAGGCAAGGCACCACTTCCTCACATGAATGAGGAGCAGCAAGTCATAACCACTCCC
TTGGGTATACAATTTGCTGTGTAGTGAAGTGGAACCAGGCTCAGGCTGCTGGTCCCAACCTCAGAGCCCCACCGCAGCCCAGTAGGGATG
CAGCACGCCCCAGAGGGCTCATGTGGGCCCCAGATGGCAATGCCACCATTGTTGATGTGACTCCAGAGCCAGTTATTAGGAAGAGCAAGC
TCACCACAGAGGAGTGGAACTGAGGCCCCCCAGATGTTGCCTCCGGTGTCCAAGCCACAGCGGTCTGGCTGTTGGGAAGATGGCCAGGAA
TGGACTCATACCATTGGCACATTAGGCTAATCCTGGTTTTATGTGAAGTCAGCAATTAAGTGTTCCCACTAGAACTGACCTAAGCCACTG
ATTAATATTTAATGAGGGAAGGTAGGGGAGAATCTAGCCATTTTATAATGCCAGAAATCTATATATGTTATCTGATGCCATTTTTCTGAA

>44708_44708_4_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000440097_LARS2_chr3_45565489_ENST00000265537_length(amino acids)=665AA_BP=526
MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQLLQEETLPRGSRGPVNGGGRLGPQARW
EVVGSKLTVDGAAKPPLAASTGAPGAVTTLAAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGPCEDPSCLTHGDYY
DNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNHRQLSLSSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQR
VSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGS
QQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLE
ALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLQASQSVILHSPEFE
DALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHE

--------------------------------------------------------------
>44708_44708_5_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000440097_LARS2_chr3_45565489_ENST00000414984_length(transcript)=2633nt_BP=2134nt
GCAGCGGAGGACCCAGCGCCTGGAACGTACCTGCGCCTCAGCCGCCGCGCGTTTGCTCCGGCCCGACTCGCGGCCTCGGCGCCCTCCCGG
CCGATTCAGCTTCACCCGGCCCAGTCGGCTGCTGCCTTGCTGTGAGTTTCCGTGTTTGGTTGCCTAAGGAGGATGTGATTTTACTTTTTT
GCTGTTTTCTTTTTCCTTTTATAATTTGAAGAGGAGAAAAGAACTCCGCTGAGCAGGCCCGGGACGGCGAAGTGCCACCAGCTACCCCAA
CAAGGACGTCTCCAGGGGAAAGGGAGTTGGAAGCAAACTTGGTCCAGCTGGCGTTGAGGTCTCAACTTCGGCTGGACTCTTAAATCCTGG
GGTCATGCCCTTCACGCTAGGCAGGTGGAAGTCTTTACTTGTACTGGGCCGGACTTGAGCCCCGACCCTTCGCCAGCATCTCCCCGCTGC
CCTCAACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACGGCACCTGGGCTAGGCCCG
GACACCTGTCTGCAGCATGGATAAGTATGACGACCTGGGCCTGGAGGCCAGTAAATTCATCGAGGACCTGAACATGTATGAGGCCTCTAA
GGATGGGCTCTTCCGAGTGGACAAGGGTGCAGGCAACAACCCCGAGTTTGAGGAAACTCGCAGGGTGTTCGCCACCAAGATGGCCAAAAT
CCACCTCCAGCAGCAGCAGCAGCAGCTCCTGCAGGAGGAGACTCTGCCCAGGGGGAGTAGAGGCCCTGTCAATGGAGGGGGCCGCCTGGG
CCCACAGGCCCGTTGGGAAGTTGTGGGCAGCAAGCTGACTGTGGATGGTGCTGCCAAGCCTCCTCTTGCTGCCTCGACAGGGGCACCTGG
GGCAGTCACCACCCTCGCTGCTGGGCAGCCCCCGTACCCACCGCAGGAGCAGAGATCCAGGCCATACCTGCATGGCACGAGGCATGGCAG
CCAGGACTGTGGTTCCAGGGAGAGCCTGGCGACTTCTGAGATGTCTGCTTTCCACCAGCCAGGCCCCTGTGAGGATCCTTCCTGCCTCAC
TCATGGAGACTATTATGACAACCTCTCCTTGGCAAGCCCAAAGTGGGGTGACAAACCAGGAGTGTCCCCCAGCATCGGCCTGAGTGTAGG
GAGTGGGTGGCCTAGCTCCCCGGGGAGTGACCCACCACTGCCCAAACCCTGCGGGGACCATCCCCTAAATCACCGACAGCTCTCCCTGAG
CTCCAGCAGGTCTTCTGAGGGTAGCCTCGGTGGTCAGAATAGTGGCATTGGTGGCCGCAGCAGCGAGAAGCCAACAGGCCTTTGGTCCAC
TGCCTCCTCCCAGCGGGTGAGCCCTGGCCTGCCTTCCCCAAACTTGGAGAACGGAGCACCAGCTGTGGGGCCTGTTCAGCCCAGGACCCC
TTCTGTGTCAGCACCCTTGGCCCTGAGCTGCCCCAGGCAAGGAGGTCTTCCAAGATCAAACTCGGGGCTGGGGGGTGAGGTTTCAGGTGT
GATGTCCAAACCCAATGTGGACCCCCAACCCTGGTTCCAGGATGGGCCCAAATCTTACCTTTCCAGTTCTGCCCCGTCATCCTCGCCAGC
TGGTCTGGACGGTTCACAGCAGGGTGCGGTCCCTGGGCTGGGGCCGAAGCCTGGCTGCACAGACCTTGGCACTGGTCCCAAGCTCAGCCC
CACCAGTCTTGTCCATCCAGTGATGTCCACCCTGCCTGAGTTATCTTGTAAAGAGGGTCCCCTGGGCTGGTCTTCTGATGGTAGCCTGGG
ATCTGTGCTCCTGGACAGCCCCAGCTCCCCTAGGGTAAGGCTGCCCTGCCAGCCCCTCGTCCCAGGTCCTGAGCTGAGACCCTCTGCTGC
TGAGTTGAAATTAGAAGCCCTCACCCAACGTCTGGAGCGAGAGATGGATGCTCACCCGAAGGCTGATTACTTTGGAGCCTGTGTGAAATG
CAGCAAAGGGGTGTTTGGGGCTGGCCAGGCCTGTCAGGCCATGGGGAACCTCTACCATGACACATGCTTCACCTGTGCAGCTTGCAGCCG
GAAGCTGAGAGGAAAAGCCTTTTATTTTGTCAACGGCAAAGTGTTTTGTGAAGAAGACTTCCTGCAAGCCTCTCAGAGCGTCATTCTCCA
CAGCCCCGAGTTTGAGGATGCTTTGTGTGCCCTGATGGTAATGGCTGCTCCACTGGCCCCTCATGTAACCTCAGAGATCTGGGCAGGCCT
GGCGCTGGTGCCGAGGAAGCTCTGTGCCCACTACACTTGGGATGCCAGTGTGCTGCTCCAGGCATGGCCTGCTGTGGACCCGGAGTTCCT
GCAGCAGCCTGAGGTTGTCCAGATGGCAGTTCTGATCAACAATAAAGCTTGTGGCAAAATTCCTGTGCCCCAACAAGTTGCCCGGGACCA
GGACAAAGTCCACGAATTTGTTCTTCAAAGCGAGCTGGGTGTCAGGCTTTTGCAAGGACGAAGCATCAAGAAGTCCTTCCTTTCCCCGAG
AACTGCCCTCATCAACTTCCTGGTGCAAGATTGACAGCCAGGAGGCTGCAGCTACCACGAGGGCCTCTGAGGAACCTCCTTCCAGGCCTG

>44708_44708_5_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000440097_LARS2_chr3_45565489_ENST00000414984_length(amino acids)=665AA_BP=526
MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQLLQEETLPRGSRGPVNGGGRLGPQARW
EVVGSKLTVDGAAKPPLAASTGAPGAVTTLAAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGPCEDPSCLTHGDYY
DNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNHRQLSLSSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQR
VSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGS
QQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLE
ALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLQASQSVILHSPEFE
DALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHE

--------------------------------------------------------------
>44708_44708_6_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000440097_LARS2_chr3_45565489_ENST00000415258_length(transcript)=4445nt_BP=2134nt
GCAGCGGAGGACCCAGCGCCTGGAACGTACCTGCGCCTCAGCCGCCGCGCGTTTGCTCCGGCCCGACTCGCGGCCTCGGCGCCCTCCCGG
CCGATTCAGCTTCACCCGGCCCAGTCGGCTGCTGCCTTGCTGTGAGTTTCCGTGTTTGGTTGCCTAAGGAGGATGTGATTTTACTTTTTT
GCTGTTTTCTTTTTCCTTTTATAATTTGAAGAGGAGAAAAGAACTCCGCTGAGCAGGCCCGGGACGGCGAAGTGCCACCAGCTACCCCAA
CAAGGACGTCTCCAGGGGAAAGGGAGTTGGAAGCAAACTTGGTCCAGCTGGCGTTGAGGTCTCAACTTCGGCTGGACTCTTAAATCCTGG
GGTCATGCCCTTCACGCTAGGCAGGTGGAAGTCTTTACTTGTACTGGGCCGGACTTGAGCCCCGACCCTTCGCCAGCATCTCCCCGCTGC
CCTCAACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACGGCACCTGGGCTAGGCCCG
GACACCTGTCTGCAGCATGGATAAGTATGACGACCTGGGCCTGGAGGCCAGTAAATTCATCGAGGACCTGAACATGTATGAGGCCTCTAA
GGATGGGCTCTTCCGAGTGGACAAGGGTGCAGGCAACAACCCCGAGTTTGAGGAAACTCGCAGGGTGTTCGCCACCAAGATGGCCAAAAT
CCACCTCCAGCAGCAGCAGCAGCAGCTCCTGCAGGAGGAGACTCTGCCCAGGGGGAGTAGAGGCCCTGTCAATGGAGGGGGCCGCCTGGG
CCCACAGGCCCGTTGGGAAGTTGTGGGCAGCAAGCTGACTGTGGATGGTGCTGCCAAGCCTCCTCTTGCTGCCTCGACAGGGGCACCTGG
GGCAGTCACCACCCTCGCTGCTGGGCAGCCCCCGTACCCACCGCAGGAGCAGAGATCCAGGCCATACCTGCATGGCACGAGGCATGGCAG
CCAGGACTGTGGTTCCAGGGAGAGCCTGGCGACTTCTGAGATGTCTGCTTTCCACCAGCCAGGCCCCTGTGAGGATCCTTCCTGCCTCAC
TCATGGAGACTATTATGACAACCTCTCCTTGGCAAGCCCAAAGTGGGGTGACAAACCAGGAGTGTCCCCCAGCATCGGCCTGAGTGTAGG
GAGTGGGTGGCCTAGCTCCCCGGGGAGTGACCCACCACTGCCCAAACCCTGCGGGGACCATCCCCTAAATCACCGACAGCTCTCCCTGAG
CTCCAGCAGGTCTTCTGAGGGTAGCCTCGGTGGTCAGAATAGTGGCATTGGTGGCCGCAGCAGCGAGAAGCCAACAGGCCTTTGGTCCAC
TGCCTCCTCCCAGCGGGTGAGCCCTGGCCTGCCTTCCCCAAACTTGGAGAACGGAGCACCAGCTGTGGGGCCTGTTCAGCCCAGGACCCC
TTCTGTGTCAGCACCCTTGGCCCTGAGCTGCCCCAGGCAAGGAGGTCTTCCAAGATCAAACTCGGGGCTGGGGGGTGAGGTTTCAGGTGT
GATGTCCAAACCCAATGTGGACCCCCAACCCTGGTTCCAGGATGGGCCCAAATCTTACCTTTCCAGTTCTGCCCCGTCATCCTCGCCAGC
TGGTCTGGACGGTTCACAGCAGGGTGCGGTCCCTGGGCTGGGGCCGAAGCCTGGCTGCACAGACCTTGGCACTGGTCCCAAGCTCAGCCC
CACCAGTCTTGTCCATCCAGTGATGTCCACCCTGCCTGAGTTATCTTGTAAAGAGGGTCCCCTGGGCTGGTCTTCTGATGGTAGCCTGGG
ATCTGTGCTCCTGGACAGCCCCAGCTCCCCTAGGGTAAGGCTGCCCTGCCAGCCCCTCGTCCCAGGTCCTGAGCTGAGACCCTCTGCTGC
TGAGTTGAAATTAGAAGCCCTCACCCAACGTCTGGAGCGAGAGATGGATGCTCACCCGAAGGCTGATTACTTTGGAGCCTGTGTGAAATG
CAGCAAAGGGGTGTTTGGGGCTGGCCAGGCCTGTCAGGCCATGGGGAACCTCTACCATGACACATGCTTCACCTGTGCAGCTTGCAGCCG
GAAGCTGAGAGGAAAAGCCTTTTATTTTGTCAACGGCAAAGTGTTTTGTGAAGAAGACTTCCTGCAAGCCTCTCAGAGCGTCATTCTCCA
CAGCCCCGAGTTTGAGGATGCTTTGTGTGCCCTGATGGTAATGGCTGCTCCACTGGCCCCTCATGTAACCTCAGAGATCTGGGCAGGCCT
GGCGCTGGTGCCGAGGAAGCTCTGTGCCCACTACACTTGGGATGCCAGTGTGCTGCTCCAGGCATGGCCTGCTGTGGACCCGGAGTTCCT
GCAGCAGCCTGAGGTTGTCCAGATGGCAGTTCTGATCAACAATAAAGCTTGTGGCAAAATTCCTGTGCCCCAACAAGTTGCCCGGGACCA
GGACAAAGTCCACGAATTTGTTCTTCAAAGCGAGCTGGGTGTCAGGCTTTTGCAAGGACGAAGCATCAAGAAGTCCTTCCTTTCCCCGAG
AACTGCCCTCATCAACTTCCTGGTGCAAGATTGACAGCCAGGAGGCTGCAGCTACCACGAGGGCCTCTGAGGAACCTCCTTCCAGGCCTG
GGATGAGGGGGCGATGTCTGCTGGCCCAGGGGAAGGGAAAAGACAAATGTCTTGACTGTTGACCTCGGTCCTGTGGCAGACTGCAGTCAA
CAGTGTGCCTCTGTAGTGTGGCCTGGTGCTGGGGTGAAGGTGAGCTGGGCAAAGGAGAAATATGAGCTACTGAGGAGGGGGTTGGACATC
CTGCCCCTCACCCCCCACCCACACTGCAGGTAGAGGAGGCCATCTGATCCCATGGGAAGCCATCAGAGACACTGCTGGTGGGAGCAGGAA
GGAGCAGTGCCCCTCGAGCAGCCAGGAAGCCTGCGGATCTGGGAAATGGCTCTGCCTTAGGCACTTCTCGGGAATTTGAGGCCAGCCTGA
GGAACTGCAGGACTCAGGTGCAATGTGCCAGCCACTTGGAACTGCTAACTGAGCCTCCAGATGGTAGTGAATGGTCTCTTTGCCTTCAGG
CTGGATGAGGAAGTCATTTAGGAAATGTTCAAATAACCAATATGTGGAAATGGACACAGGGATCTTCTGAAGTTGCTTTGAATCAAAAGG
CAGGCAGTGCTGGTTCCTCTGCCTGTGTCCCCACCACTCCCCAGCTCTGTCATGCAGGCCTGTCCTCCCCAACCCCAGCTGGATGTGCCT
CCCAGGCCTGCTGTGGTTCTGACACACAGGATCCCAGGCAAGGCACCACTTCCTCACATGAATGAGGAGCAGCAAGTCATAACCACTCCC
TTGGGTATACAATTTGCTGTGTAGTGAAGTGGAACCAGGCTCAGGCTGCTGGTCCCAACCTCAGAGCCCCACCGCAGCCCAGTAGGGATG
CAGCACGCCCCAGAGGGCTCATGTGGGCCCCAGATGGCAATGCCACCATTGTTGATGTGACTCCAGAGCCAGTTATTAGGAAGAGCAAGC
TCACCACAGAGGAGTGGAACTGAGGCCCCCCAGATGTTGCCTCCGGTGTCCAAGCCACAGCGGTCTGGCTGTTGGGAAGATGGCCAGGAA
TGGACTCATACCATTGGCACATTAGGCTAATCCTGGTTTTATGTGAAGTCAGCAATTAAGTGTTCCCACTAGAACTGACCTAAGCCACTG
ATTAATATTTAATGAGGGAAGGTAGGGGAGAATCTAGCCATTTTATAATGCCAGAAATCTATATATGTTATCTGATGCCATTTTTCTGAA
GTAGCCTCACATGTGGTCCCCCTGCAGTTCAGCAGTTAACAGATGACTTTTTTAGTGTAATAAAATGTTTATCATCTATGACTTCAGGAC
ATATGTGTGATCCTGGAATACACCATATTCCAATTTCAGAGTTAATTACAAACAGATTGAGGTATTCCATCATCATCGGAAGCATTGGCT
GTGTGTCTGACTCCACATGGAATGCTATAAAGTGGGATACATGTGGTTCTTCTTGTTCCAGAACTTACAGTCCATGGTAGACAACACTGA
TACAGGCAAACTAGCAACAGCAATTAAGTCACTGGTTCTCAGACTTAATACTCTGCCTGGTCCTCATGCCCAGATATTCCAATTTAATTG
GTCCATGGTGTGGCTTGAACACCAGGAATCTTTAAAACTCCACAAGTGATTCTAATGGGCAGCAAAGTTTGAGAATCACTGGACACATTG
ATGCACTTGAGCCATCATTTCTATCTAGTTCTTCCTCTTCCTAATCTTCAGGTTAGCGGGGATAAGTTTGGTCCAGGACCAAGAGTTGGA
CCAAAAGGGAAGACAGGGGCCAGAAGTCTAGAGTGCTAGAGCCGACTTGAATGTACTCAGTCTCATTGCACATGGCAGTGAATATGGATT

>44708_44708_6_LIMD1-LARS2_LIMD1_chr3_45707209_ENST00000440097_LARS2_chr3_45565489_ENST00000415258_length(amino acids)=665AA_BP=526
MDKYDDLGLEASKFIEDLNMYEASKDGLFRVDKGAGNNPEFEETRRVFATKMAKIHLQQQQQQLLQEETLPRGSRGPVNGGGRLGPQARW
EVVGSKLTVDGAAKPPLAASTGAPGAVTTLAAGQPPYPPQEQRSRPYLHGTRHGSQDCGSRESLATSEMSAFHQPGPCEDPSCLTHGDYY
DNLSLASPKWGDKPGVSPSIGLSVGSGWPSSPGSDPPLPKPCGDHPLNHRQLSLSSSRSSEGSLGGQNSGIGGRSSEKPTGLWSTASSQR
VSPGLPSPNLENGAPAVGPVQPRTPSVSAPLALSCPRQGGLPRSNSGLGGEVSGVMSKPNVDPQPWFQDGPKSYLSSSAPSSSPAGLDGS
QQGAVPGLGPKPGCTDLGTGPKLSPTSLVHPVMSTLPELSCKEGPLGWSSDGSLGSVLLDSPSSPRVRLPCQPLVPGPELRPSAAELKLE
ALTQRLEREMDAHPKADYFGACVKCSKGVFGAGQACQAMGNLYHDTCFTCAACSRKLRGKAFYFVNGKVFCEEDFLQASQSVILHSPEFE
DALCALMVMAAPLAPHVTSEIWAGLALVPRKLCAHYTWDASVLLQAWPAVDPEFLQQPEVVQMAVLINNKACGKIPVPQQVARDQDKVHE

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Fusion Gene PPI Analysis for LIMD1-LARS2


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneLIMD1chr3:45637779chr3:45557586ENST00000273317-18186_260469.3333333333333677.0EGLN1/PHD2
HgeneLIMD1chr3:45707209chr3:45565489ENST00000273317+38186_260526.0677.0EGLN1/PHD2
HgeneLIMD1chr3:45637779chr3:45557586ENST00000273317-18404_442469.3333333333333677.0RB1
HgeneLIMD1chr3:45707209chr3:45565489ENST00000273317+38404_442526.0677.0RB1


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LIMD1-LARS2


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LIMD1-LARS2


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource