FusionGDB Logo

Home

Download

Statistics

Examples

Help

Contact
Center for Computational Systems Medicine
leaf

Fusion Gene Summary

leaf

Fusion Gene ORF analysis

leaf

Fusion Genomic Features

leaf

Fusion Protein Features

leaf

Fusion Gene Sequence

leaf

Fusion Gene PPI analysis

leaf

Related Drugs

leaf

Related Diseases

Fusion gene:LIMK2-RUFY1 (FusionGDB2 ID:44725)

Fusion Gene Summary for LIMK2-RUFY1

check button Fusion gene summary
Fusion gene informationFusion gene name: LIMK2-RUFY1
Fusion gene ID: 44725
HgeneTgene
Gene symbol

LIMK2

RUFY1

Gene ID

3985

80230

Gene nameLIM domain kinase 2RUN and FYVE domain containing 1
Synonyms-RABIP4|ZFYVE12
Cytomap

22q12.2

5q35.3

Type of geneprotein-codingprotein-coding
DescriptionLIM domain kinase 2RUN and FYVE domain-containing protein 1FYVE-finger protein EIP1la-binding protein 1rab4-interacting proteinzinc finger FYVE domain-containing protein 12
Modification date2020031320200327
UniProtAcc..
Ensembl transtripts involved in fusion geneENST00000331728, ENST00000444929, 
ENST00000333611, ENST00000340552, 
ENST00000406516, ENST00000467301, 
ENST00000508797, ENST00000319449, 
ENST00000377001, ENST00000393438, 
ENST00000437570, 
Fusion gene scores* DoF score11 X 7 X 7=5397 X 10 X 6=420
# samples 1310
** MAII scorelog2(13/539*10)=-2.05177364972405
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(10/420*10)=-2.0703893278914
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LIMK2 [Title/Abstract] AND RUFY1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLIMK2(31621805)-RUFY1(179007948), # samples:3
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneLIMK2

GO:0006468

protein phosphorylation

22328514

HgeneLIMK2

GO:0030953

astral microtubule organization

22328514


check buttonFusion gene breakpoints across LIMK2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across RUFY1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-A8-A07O-01ALIMK2chr22

31621805

-RUFY1chr5

179007948

+
ChimerDB4BRCATCGA-A8-A07O-01ALIMK2chr22

31621805

+RUFY1chr5

179007948

+
ChimerDB4BRCATCGA-A8-A07OLIMK2chr22

31621805

+RUFY1chr5

179007947

+


Top

Fusion Gene ORF analysis for LIMK2-RUFY1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000331728ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007948

+
5CDS-intronENST00000331728ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007947

+
5CDS-intronENST00000444929ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007948

+
5CDS-intronENST00000444929ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007947

+
In-frameENST00000331728ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007948

+
In-frameENST00000331728ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007947

+
In-frameENST00000331728ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007948

+
In-frameENST00000331728ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007947

+
In-frameENST00000331728ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007948

+
In-frameENST00000331728ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007947

+
In-frameENST00000331728ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007948

+
In-frameENST00000331728ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007947

+
In-frameENST00000444929ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007948

+
In-frameENST00000444929ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007947

+
In-frameENST00000444929ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007948

+
In-frameENST00000444929ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007947

+
In-frameENST00000444929ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007948

+
In-frameENST00000444929ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007947

+
In-frameENST00000444929ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007948

+
In-frameENST00000444929ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000333611ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000333611ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000333611ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000333611ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000333611ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000333611ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000333611ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000333611ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000340552ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000340552ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000340552ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000340552ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000340552ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000340552ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000340552ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000340552ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000406516ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000406516ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000406516ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000406516ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000406516ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000406516ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000406516ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000406516ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000467301ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000467301ENST00000319449LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000467301ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000467301ENST00000377001LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000467301ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000467301ENST00000393438LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-3CDSENST00000467301ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-3CDSENST00000467301ENST00000437570LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-intronENST00000333611ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-intronENST00000333611ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-intronENST00000340552ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-intronENST00000340552ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-intronENST00000406516ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-intronENST00000406516ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007947

+
intron-intronENST00000467301ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007948

+
intron-intronENST00000467301ENST00000508797LIMK2chr22

31621805

+RUFY1chr5

179007947

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000444929LIMK2chr2231621805+ENST00000319449RUFY1chr5179007948+1990246821482466
ENST00000444929LIMK2chr2231621805+ENST00000377001RUFY1chr5179007948+21272466561627323
ENST00000444929LIMK2chr2231621805+ENST00000437570RUFY1chr5179007948+1975246821482466
ENST00000444929LIMK2chr2231621805+ENST00000393438RUFY1chr5179007948+1976246821482466
ENST00000331728LIMK2chr2231621805+ENST00000319449RUFY1chr5179007948+1974230661466466
ENST00000331728LIMK2chr2231621805+ENST00000377001RUFY1chr5179007948+21112306401611323
ENST00000331728LIMK2chr2231621805+ENST00000437570RUFY1chr5179007948+1959230661466466
ENST00000331728LIMK2chr2231621805+ENST00000393438RUFY1chr5179007948+1960230661466466
ENST00000444929LIMK2chr2231621805+ENST00000319449RUFY1chr5179007947+1990246821482466
ENST00000444929LIMK2chr2231621805+ENST00000377001RUFY1chr5179007947+21272466561627323
ENST00000444929LIMK2chr2231621805+ENST00000437570RUFY1chr5179007947+1975246821482466
ENST00000444929LIMK2chr2231621805+ENST00000393438RUFY1chr5179007947+1976246821482466
ENST00000331728LIMK2chr2231621805+ENST00000319449RUFY1chr5179007947+1974230661466466
ENST00000331728LIMK2chr2231621805+ENST00000377001RUFY1chr5179007947+21112306401611323
ENST00000331728LIMK2chr2231621805+ENST00000437570RUFY1chr5179007947+1959230661466466
ENST00000331728LIMK2chr2231621805+ENST00000393438RUFY1chr5179007947+1960230661466466

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000444929ENST00000319449LIMK2chr2231621805+RUFY1chr5179007948+0.011377590.98862237
ENST00000444929ENST00000377001LIMK2chr2231621805+RUFY1chr5179007948+0.010324790.9896752
ENST00000444929ENST00000437570LIMK2chr2231621805+RUFY1chr5179007948+0.0113052020.98869485
ENST00000444929ENST00000393438LIMK2chr2231621805+RUFY1chr5179007948+0.0113255480.98867446
ENST00000331728ENST00000319449LIMK2chr2231621805+RUFY1chr5179007948+0.010988120.9890119
ENST00000331728ENST00000377001LIMK2chr2231621805+RUFY1chr5179007948+0.0092269920.9907731
ENST00000331728ENST00000437570LIMK2chr2231621805+RUFY1chr5179007948+0.0109114690.98908854
ENST00000331728ENST00000393438LIMK2chr2231621805+RUFY1chr5179007948+0.0108990330.989101
ENST00000444929ENST00000319449LIMK2chr2231621805+RUFY1chr5179007947+0.011377590.98862237
ENST00000444929ENST00000377001LIMK2chr2231621805+RUFY1chr5179007947+0.010324790.9896752
ENST00000444929ENST00000437570LIMK2chr2231621805+RUFY1chr5179007947+0.0113052020.98869485
ENST00000444929ENST00000393438LIMK2chr2231621805+RUFY1chr5179007947+0.0113255480.98867446
ENST00000331728ENST00000319449LIMK2chr2231621805+RUFY1chr5179007947+0.010988120.9890119
ENST00000331728ENST00000377001LIMK2chr2231621805+RUFY1chr5179007947+0.0092269920.9907731
ENST00000331728ENST00000437570LIMK2chr2231621805+RUFY1chr5179007947+0.0109114690.98908854
ENST00000331728ENST00000393438LIMK2chr2231621805+RUFY1chr5179007947+0.0108990330.989101

Top

Fusion Genomic Features for LIMK2-RUFY1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
LIMK2chr2231621805+RUFY1chr5179007947+4.42E-070.9999995
LIMK2chr2231621805+RUFY1chr5179007947+4.42E-070.9999995
LIMK2chr2231621805+RUFY1chr5179007947+4.42E-070.9999995
LIMK2chr2231621805+RUFY1chr5179007947+4.42E-070.9999995

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

Top

Fusion Protein Features for LIMK2-RUFY1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr22:31621805/chr5:179007948)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
..
FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneRUFY1chr22:31621805chr5:179007947ENST00000319449518321_374296709.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007947ENST00000319449518405_617296709.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007947ENST00000377001519321_374296522.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007947ENST00000377001519405_617296522.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007947ENST00000393438518321_374188601.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007947ENST00000393438518405_617188601.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007947ENST00000437570417321_374188601.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007947ENST00000437570417405_617188601.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007948ENST00000319449518321_374296709.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007948ENST00000319449518405_617296709.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007948ENST00000377001519321_374296522.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007948ENST00000377001519405_617296522.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007948ENST00000393438518321_374188601.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007948ENST00000393438518405_617188601.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007948ENST00000437570417321_374188601.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007948ENST00000437570417405_617188601.0Coiled coilOntology_term=ECO:0000255
TgeneRUFY1chr22:31621805chr5:179007947ENST00000319449518642_700296709.0Zinc fingerFYVE-type
TgeneRUFY1chr22:31621805chr5:179007947ENST00000377001519642_700296522.0Zinc fingerFYVE-type
TgeneRUFY1chr22:31621805chr5:179007947ENST00000393438518642_700188601.0Zinc fingerFYVE-type
TgeneRUFY1chr22:31621805chr5:179007947ENST00000437570417642_700188601.0Zinc fingerFYVE-type
TgeneRUFY1chr22:31621805chr5:179007948ENST00000319449518642_700296709.0Zinc fingerFYVE-type
TgeneRUFY1chr22:31621805chr5:179007948ENST00000377001519642_700296522.0Zinc fingerFYVE-type
TgeneRUFY1chr22:31621805chr5:179007948ENST00000393438518642_700188601.0Zinc fingerFYVE-type
TgeneRUFY1chr22:31621805chr5:179007948ENST00000437570417642_700188601.0Zinc fingerFYVE-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLIMK2chr22:31621805chr5:179007947ENST00000331728+21612_6338639.0DomainLIM zinc-binding 1
HgeneLIMK2chr22:31621805chr5:179007947ENST00000331728+216152_23938639.0DomainPDZ
HgeneLIMK2chr22:31621805chr5:179007947ENST00000331728+216331_60838639.0DomainProtein kinase
HgeneLIMK2chr22:31621805chr5:179007947ENST00000331728+21672_12438639.0DomainLIM zinc-binding 2
HgeneLIMK2chr22:31621805chr5:179007947ENST00000333611+11512_630618.0DomainLIM zinc-binding 1
HgeneLIMK2chr22:31621805chr5:179007947ENST00000333611+115152_2390618.0DomainPDZ
HgeneLIMK2chr22:31621805chr5:179007947ENST00000333611+115331_6080618.0DomainProtein kinase
HgeneLIMK2chr22:31621805chr5:179007947ENST00000333611+11572_1240618.0DomainLIM zinc-binding 2
HgeneLIMK2chr22:31621805chr5:179007947ENST00000340552+11512_630687.0DomainLIM zinc-binding 1
HgeneLIMK2chr22:31621805chr5:179007947ENST00000340552+115152_2390687.0DomainPDZ
HgeneLIMK2chr22:31621805chr5:179007947ENST00000340552+115331_6080687.0DomainProtein kinase
HgeneLIMK2chr22:31621805chr5:179007947ENST00000340552+11572_1240687.0DomainLIM zinc-binding 2
HgeneLIMK2chr22:31621805chr5:179007948ENST00000331728+21612_6338639.0DomainLIM zinc-binding 1
HgeneLIMK2chr22:31621805chr5:179007948ENST00000331728+216152_23938639.0DomainPDZ
HgeneLIMK2chr22:31621805chr5:179007948ENST00000331728+216331_60838639.0DomainProtein kinase
HgeneLIMK2chr22:31621805chr5:179007948ENST00000331728+21672_12438639.0DomainLIM zinc-binding 2
HgeneLIMK2chr22:31621805chr5:179007948ENST00000333611+11512_630618.0DomainLIM zinc-binding 1
HgeneLIMK2chr22:31621805chr5:179007948ENST00000333611+115152_2390618.0DomainPDZ
HgeneLIMK2chr22:31621805chr5:179007948ENST00000333611+115331_6080618.0DomainProtein kinase
HgeneLIMK2chr22:31621805chr5:179007948ENST00000333611+11572_1240618.0DomainLIM zinc-binding 2
HgeneLIMK2chr22:31621805chr5:179007948ENST00000340552+11512_630687.0DomainLIM zinc-binding 1
HgeneLIMK2chr22:31621805chr5:179007948ENST00000340552+115152_2390687.0DomainPDZ
HgeneLIMK2chr22:31621805chr5:179007948ENST00000340552+115331_6080687.0DomainProtein kinase
HgeneLIMK2chr22:31621805chr5:179007948ENST00000340552+11572_1240687.0DomainLIM zinc-binding 2
HgeneLIMK2chr22:31621805chr5:179007947ENST00000331728+216337_34538639.0Nucleotide bindingATP
HgeneLIMK2chr22:31621805chr5:179007947ENST00000333611+115337_3450618.0Nucleotide bindingATP
HgeneLIMK2chr22:31621805chr5:179007947ENST00000340552+115337_3450687.0Nucleotide bindingATP
HgeneLIMK2chr22:31621805chr5:179007948ENST00000331728+216337_34538639.0Nucleotide bindingATP
HgeneLIMK2chr22:31621805chr5:179007948ENST00000333611+115337_3450618.0Nucleotide bindingATP
HgeneLIMK2chr22:31621805chr5:179007948ENST00000340552+115337_3450687.0Nucleotide bindingATP
TgeneRUFY1chr22:31621805chr5:179007947ENST00000319449518139_271296709.0DomainRUN
TgeneRUFY1chr22:31621805chr5:179007947ENST00000377001519139_271296522.0DomainRUN
TgeneRUFY1chr22:31621805chr5:179007947ENST00000393438518139_271188601.0DomainRUN
TgeneRUFY1chr22:31621805chr5:179007947ENST00000437570417139_271188601.0DomainRUN
TgeneRUFY1chr22:31621805chr5:179007948ENST00000319449518139_271296709.0DomainRUN
TgeneRUFY1chr22:31621805chr5:179007948ENST00000377001519139_271296522.0DomainRUN
TgeneRUFY1chr22:31621805chr5:179007948ENST00000393438518139_271188601.0DomainRUN
TgeneRUFY1chr22:31621805chr5:179007948ENST00000437570417139_271188601.0DomainRUN


Top

Fusion Gene Sequence for LIMK2-RUFY1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>44725_44725_1_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007947_ENST00000319449_length(transcript)=1974nt_BP=230nt
GTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTGTCCCCCGCCTCCTCCT
CCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGACCACATTGCTCCAAGC
CAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCTTGATCAAAAAAATTAT
GTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGACTAACTCAAAGCTTCAA
GAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGA
AGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTAC
AGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAA
ATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAA
GCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAA
ACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCAC
AAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAA
TTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAA
CAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTC
CAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTG
AAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATC
TTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTG
CAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTT
GGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACC
GGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCA
GATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGT
TTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGAC

>44725_44725_1_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007947_ENST00000319449_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_2_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007947_ENST00000377001_length(transcript)=2111nt_BP=230nt
GTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTGTCCCCCGCCTCCTCCT
CCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGACCACATTGCTCCAAGC
CAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCTTGATCAAAAAAATTAT
GTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGACTAACTCAAAGCTTCAA
GAAGAGGAAGAGAGAATGAAAGGACAGGACAAAGGAGGGCTGAGCCGAGGAAGAGAGCTTGCTGCCAGCTGCCCGGCAGTCTCCTTGCTG
GACACATCTTGTCTCCTGTTAGCAGGAGGGGGGTGCTCAGCCCTTCTGAGGCTTTCCACAGCTTTCAGCTGCAACAGACCGAATTTGCTC
ACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGATAACAAAACAGGATAC
CAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTACAGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAA
AGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAAATGGAAATTGCAATGAAGTTACTGGAAAAGGACAC
CCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAAGCGATTAATTTACAGATGTTTCACAAAGCTCAGAA
TGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCAGCATGAAACAAATGGA
AGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGC
CCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCA
GCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCT
TCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCT
GAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTGAAAGATGACGAAGCGACACACTGTAGGCAGTGTGA
GAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATCTTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCT
GCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGT
CCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAA
AGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATT
AACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCAGATACAACTTCATGATTTTGCTACTATCATTTTTC
ACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTC
ATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGACAAGAGATCTGCCATTTCATGCCCTTGTGACTACCT

>44725_44725_2_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007947_ENST00000377001_length(amino acids)=323AA_BP=
METYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAES
SLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQREL
QHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEF

--------------------------------------------------------------
>44725_44725_3_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007947_ENST00000393438_length(transcript)=1960nt_BP=230nt
GTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTGTCCCCCGCCTCCTCCT
CCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGACCACATTGCTCCAAGC
CAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCTTGATCAAAAAAATTAT
GTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGACTAACTCAAAGCTTCAA
GAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGA
AGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTAC
AGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAA
ATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAA
GCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAA
ACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCAC
AAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAA
TTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAA
CAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTC
CAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTG
AAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATC
TTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTG
CAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTT
GGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACC
GGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCA
GATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGT
TTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGAC

>44725_44725_3_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007947_ENST00000393438_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_4_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007947_ENST00000437570_length(transcript)=1959nt_BP=230nt
GTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTGTCCCCCGCCTCCTCCT
CCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGACCACATTGCTCCAAGC
CAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCTTGATCAAAAAAATTAT
GTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGACTAACTCAAAGCTTCAA
GAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGA
AGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTAC
AGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAA
ATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAA
GCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAA
ACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCAC
AAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAA
TTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAA
CAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTC
CAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTG
AAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATC
TTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTG
CAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTT
GGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACC
GGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCA
GATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGT
TTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGAC

>44725_44725_4_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007947_ENST00000437570_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_5_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007948_ENST00000319449_length(transcript)=1974nt_BP=230nt
GTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTGTCCCCCGCCTCCTCCT
CCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGACCACATTGCTCCAAGC
CAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCTTGATCAAAAAAATTAT
GTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGACTAACTCAAAGCTTCAA
GAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGA
AGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTAC
AGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAA
ATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAA
GCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAA
ACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCAC
AAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAA
TTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAA
CAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTC
CAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTG
AAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATC
TTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTG
CAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTT
GGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACC
GGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCA
GATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGT
TTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGAC

>44725_44725_5_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007948_ENST00000319449_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_6_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007948_ENST00000377001_length(transcript)=2111nt_BP=230nt
GTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTGTCCCCCGCCTCCTCCT
CCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGACCACATTGCTCCAAGC
CAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCTTGATCAAAAAAATTAT
GTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGACTAACTCAAAGCTTCAA
GAAGAGGAAGAGAGAATGAAAGGACAGGACAAAGGAGGGCTGAGCCGAGGAAGAGAGCTTGCTGCCAGCTGCCCGGCAGTCTCCTTGCTG
GACACATCTTGTCTCCTGTTAGCAGGAGGGGGGTGCTCAGCCCTTCTGAGGCTTTCCACAGCTTTCAGCTGCAACAGACCGAATTTGCTC
ACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGATAACAAAACAGGATAC
CAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTACAGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAA
AGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAAATGGAAATTGCAATGAAGTTACTGGAAAAGGACAC
CCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAAGCGATTAATTTACAGATGTTTCACAAAGCTCAGAA
TGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCAGCATGAAACAAATGGA
AGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGC
CCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCA
GCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCT
TCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCT
GAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTGAAAGATGACGAAGCGACACACTGTAGGCAGTGTGA
GAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATCTTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCT
GCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGT
CCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAA
AGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATT
AACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCAGATACAACTTCATGATTTTGCTACTATCATTTTTC
ACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTC
ATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGACAAGAGATCTGCCATTTCATGCCCTTGTGACTACCT

>44725_44725_6_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007948_ENST00000377001_length(amino acids)=323AA_BP=
METYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAES
SLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQREL
QHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEF

--------------------------------------------------------------
>44725_44725_7_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007948_ENST00000393438_length(transcript)=1960nt_BP=230nt
GTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTGTCCCCCGCCTCCTCCT
CCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGACCACATTGCTCCAAGC
CAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCTTGATCAAAAAAATTAT
GTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGACTAACTCAAAGCTTCAA
GAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGA
AGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTAC
AGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAA
ATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAA
GCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAA
ACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCAC
AAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAA
TTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAA
CAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTC
CAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTG
AAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATC
TTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTG
CAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTT
GGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACC
GGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCA
GATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGT
TTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGAC

>44725_44725_7_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007948_ENST00000393438_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_8_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007948_ENST00000437570_length(transcript)=1959nt_BP=230nt
GTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTGTCCCCCGCCTCCTCCT
CCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGACCACATTGCTCCAAGC
CAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCTTGATCAAAAAAATTAT
GTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGACTAACTCAAAGCTTCAA
GAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGA
AGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTAC
AGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAA
ATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAA
GCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAA
ACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCAC
AAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAA
TTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAA
CAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTC
CAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTG
AAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATC
TTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTG
CAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTT
GGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACC
GGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCA
GATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGT
TTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGAC

>44725_44725_8_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000331728_RUFY1_chr5_179007948_ENST00000437570_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_9_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007947_ENST00000319449_length(transcript)=1990nt_BP=246nt
GTTCGCGCCTGGGGCTGTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTG
TCCCCCGCCTCCTCCTCCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGA
CCACATTGCTCCAAGCCAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCT
TGATCAAAAAAATTATGTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGAC
TAACTCAAAGCTTCAAGAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGA
ATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGG
TCTGGATGAAATGTACAGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAAT
TGGAATGAAAACCGAAATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCA
GCTGGAAGAAGTCAAAGCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCAC
ATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGC
TGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTC
AAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACT
CAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGA
GCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAA
GGGCCACGCCTGGCTGAAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCG
GAACTGTGGCCACATCTTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTG
CCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGT
GGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAG
ACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACA
TCACGGCTCTGGTTCAGATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGT
TCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGC
CTTCTCTGCTTCAGACAAGAGATCTGCCATTTCATGCCCTTGTGACTACCTATCATTGGCCCTGCAATAAAATCATTTATTTTTCACTCT

>44725_44725_9_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007947_ENST00000319449_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_10_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007947_ENST00000377001_length(transcript)=2127nt_BP=246nt
GTTCGCGCCTGGGGCTGTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTG
TCCCCCGCCTCCTCCTCCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGA
CCACATTGCTCCAAGCCAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCT
TGATCAAAAAAATTATGTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGAC
TAACTCAAAGCTTCAAGAAGAGGAAGAGAGAATGAAAGGACAGGACAAAGGAGGGCTGAGCCGAGGAAGAGAGCTTGCTGCCAGCTGCCC
GGCAGTCTCCTTGCTGGACACATCTTGTCTCCTGTTAGCAGGAGGGGGGTGCTCAGCCCTTCTGAGGCTTTCCACAGCTTTCAGCTGCAA
CAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGA
TAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTACAGTGATGTGTGGAAGCAGC
TAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAAATGGAAATTGCAATGAAGT
TACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAAGCGATTAATTTACAGATGT
TTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCA
GCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGG
GCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGC
AAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAA
AGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACC
TCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTGAAAGATGACGAAGCGACAC
ACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATCTTCTGCAACACCTGCTCCA
GCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGG
CCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCC
AAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTG
TGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCAGATACAACTTCATGATTTT
GCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCT
TCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGACAAGAGATCTGCCATTTCAT

>44725_44725_10_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007947_ENST00000377001_length(amino acids)=323AA_BP=
METYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAES
SLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQREL
QHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEF

--------------------------------------------------------------
>44725_44725_11_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007947_ENST00000393438_length(transcript)=1976nt_BP=246nt
GTTCGCGCCTGGGGCTGTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTG
TCCCCCGCCTCCTCCTCCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGA
CCACATTGCTCCAAGCCAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCT
TGATCAAAAAAATTATGTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGAC
TAACTCAAAGCTTCAAGAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGA
ATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGG
TCTGGATGAAATGTACAGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAAT
TGGAATGAAAACCGAAATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCA
GCTGGAAGAAGTCAAAGCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCAC
ATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGC
TGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTC
AAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACT
CAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGA
GCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAA
GGGCCACGCCTGGCTGAAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCG
GAACTGTGGCCACATCTTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTG
CCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGT
GGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAG
ACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACA
TCACGGCTCTGGTTCAGATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGT
TCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGC

>44725_44725_11_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007947_ENST00000393438_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_12_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007947_ENST00000437570_length(transcript)=1975nt_BP=246nt
GTTCGCGCCTGGGGCTGTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTG
TCCCCCGCCTCCTCCTCCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGA
CCACATTGCTCCAAGCCAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCT
TGATCAAAAAAATTATGTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGAC
TAACTCAAAGCTTCAAGAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGA
ATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGG
TCTGGATGAAATGTACAGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAAT
TGGAATGAAAACCGAAATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCA
GCTGGAAGAAGTCAAAGCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCAC
ATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGC
TGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTC
AAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACT
CAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGA
GCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAA
GGGCCACGCCTGGCTGAAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCG
GAACTGTGGCCACATCTTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTG
CCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGT
GGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAG
ACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACA
TCACGGCTCTGGTTCAGATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGT
TCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGC

>44725_44725_12_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007947_ENST00000437570_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_13_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007948_ENST00000319449_length(transcript)=1990nt_BP=246nt
GTTCGCGCCTGGGGCTGTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTG
TCCCCCGCCTCCTCCTCCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGA
CCACATTGCTCCAAGCCAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCT
TGATCAAAAAAATTATGTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGAC
TAACTCAAAGCTTCAAGAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGA
ATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGG
TCTGGATGAAATGTACAGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAAT
TGGAATGAAAACCGAAATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCA
GCTGGAAGAAGTCAAAGCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCAC
ATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGC
TGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTC
AAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACT
CAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGA
GCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAA
GGGCCACGCCTGGCTGAAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCG
GAACTGTGGCCACATCTTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTG
CCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGT
GGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAG
ACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACA
TCACGGCTCTGGTTCAGATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGT
TCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGC
CTTCTCTGCTTCAGACAAGAGATCTGCCATTTCATGCCCTTGTGACTACCTATCATTGGCCCTGCAATAAAATCATTTATTTTTCACTCT

>44725_44725_13_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007948_ENST00000319449_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_14_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007948_ENST00000377001_length(transcript)=2127nt_BP=246nt
GTTCGCGCCTGGGGCTGTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTG
TCCCCCGCCTCCTCCTCCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGA
CCACATTGCTCCAAGCCAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCT
TGATCAAAAAAATTATGTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGAC
TAACTCAAAGCTTCAAGAAGAGGAAGAGAGAATGAAAGGACAGGACAAAGGAGGGCTGAGCCGAGGAAGAGAGCTTGCTGCCAGCTGCCC
GGCAGTCTCCTTGCTGGACACATCTTGTCTCCTGTTAGCAGGAGGGGGGTGCTCAGCCCTTCTGAGGCTTTCCACAGCTTTCAGCTGCAA
CAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGAATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGA
TAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGGTCTGGATGAAATGTACAGTGATGTGTGGAAGCAGC
TAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAATTGGAATGAAAACCGAAATGGAAATTGCAATGAAGT
TACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCAGCTGGAAGAAGTCAAAGCGATTAATTTACAGATGT
TTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCACATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCA
GCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGCTGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGG
GCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTCAAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGC
AAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACTCAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAA
AGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGAGCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACC
TCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAAGGGCCACGCCTGGCTGAAAGATGACGAAGCGACAC
ACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCGGAACTGTGGCCACATCTTCTGCAACACCTGCTCCA
GCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTGCCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGG
CCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGTGGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCC
AAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAGACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTG
TGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACATCACGGCTCTGGTTCAGATACAACTTCATGATTTT
GCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGTTCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCT
TCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGCCTTCTCTGCTTCAGACAAGAGATCTGCCATTTCAT

>44725_44725_14_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007948_ENST00000377001_length(amino acids)=323AA_BP=
METYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELELQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAES
SLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERARQGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQREL
QHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKICEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEF

--------------------------------------------------------------
>44725_44725_15_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007948_ENST00000393438_length(transcript)=1976nt_BP=246nt
GTTCGCGCCTGGGGCTGTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTG
TCCCCCGCCTCCTCCTCCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGA
CCACATTGCTCCAAGCCAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCT
TGATCAAAAAAATTATGTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGAC
TAACTCAAAGCTTCAAGAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGA
ATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGG
TCTGGATGAAATGTACAGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAAT
TGGAATGAAAACCGAAATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCA
GCTGGAAGAAGTCAAAGCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCAC
ATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGC
TGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTC
AAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACT
CAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGA
GCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAA
GGGCCACGCCTGGCTGAAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCG
GAACTGTGGCCACATCTTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTG
CCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGT
GGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAG
ACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACA
TCACGGCTCTGGTTCAGATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGT
TCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGC

>44725_44725_15_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007948_ENST00000393438_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------
>44725_44725_16_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007948_ENST00000437570_length(transcript)=1975nt_BP=246nt
GTTCGCGCCTGGGGCTGTGGTCTTCCCGCGCCTGAGGCGGCGGCGGCAGGAGCTGAGGGGAGTTGTAGGGAACTGAGGGGAGCTGCTGTG
TCCCCCGCCTCCTCCTCCCCATTTCCGCGCTCCCGGGACCATGTCCGCGCTGGCGGGTGAAGATGTCTGGAGGTGTCCAGGCTGTGGGGA
CCACATTGCTCCAAGCCAGATATGGTACAGGACTGTCAACGAAACCTGGCACGGCTCTTGCTTCCGGCATGAAAGAATTACTGATGTCCT
TGATCAAAAAAATTATGTGGAAGAACTTAACCGGCACTTGAGCTGCACAGTTGGGGATCTTCAAACCAAGATAGATGGCTTGGAAAAGAC
TAACTCAAAGCTTCAAGAAGAGCTTTCAGCTGCAACAGACCGAATTTGCTCACTTCAAGAAGAACAGCAGCAGTTAAGAGAACAAAATGA
ATTAATTCGAGAAAGAAGTGAAAAGAGTGTAGAGATAACAAAACAGGATACCAAAGTTGAGCTGGAGACTTACAAGCAAACTCGGCAAGG
TCTGGATGAAATGTACAGTGATGTGTGGAAGCAGCTAAAAGAGGAGAAGAAAGTCCGGTTGGAACTGGAAAAAGAACTGGAGTTACAAAT
TGGAATGAAAACCGAAATGGAAATTGCAATGAAGTTACTGGAAAAGGACACCCACGAGAAGCAGGACACACTAGTTGCCCTCCGCCAGCA
GCTGGAAGAAGTCAAAGCGATTAATTTACAGATGTTTCACAAAGCTCAGAATGCAGAGAGCAGTTTGCAGCAGAAGAATGAAGCCATCAC
ATCCTTTGAAGGAAAAACCAACCAAGTTATGTCCAGCATGAAACAAATGGAAGAAAGGTTGCAGCACTCGGAGCGGGCGAGGCAGGGGGC
TGAGGAGCGGAGCCACAAGCTGCAGCAGGAGCTGGGCGGGAGGATCGGCGCCCTGCAGCTGCAGCTCTCCCAGCTGCACGAGCAATGCTC
AAGCCTGGAGAAAGAATTGAAATCAGAAAAAGAGCAAAGACAGGCTCTTCAGCGCGAATTACAGCACGAGAAAGACACTTCCTCTCTACT
CAGGATGGAGCTGCAACAAGTGGAAGGACTGAAAAAGGAGTTGCGGGAGCTTCAGGACGAGAAGGCAGAGCTGCAGAAGATCTGCGAGGA
GCAGGAACAAGCCCTCCAGGAAATGGGCCTGCACCTCAGCCAGTCCAAGCTGAAGATGGAAGATATAAAAGAAGTGAACCAGGCACTGAA
GGGCCACGCCTGGCTGAAAGATGACGAAGCGACACACTGTAGGCAGTGTGAGAAGGAGTTCTCCATTTCCCGGAGAAAGCACCACTGCCG
GAACTGTGGCCACATCTTCTGCAACACCTGCTCCAGCAACGAGCTGGCCCTGCCCTCCTACCCCAAGCCGGTGCGAGTGTGCGACAGCTG
CCACACCCTGCTCCTGCAGCGCTGCTCCTCCACGGCCTCCTGAACGTCCGTCCTCAGGAGCACAGCCTCACGGACAGTGCCAAACCCTGT
GGGTCTCCAGGGGCTTGGGAAATGTGTTCTTTCCCAAGAGTATCAAAGGAAAGAATCAAATTTCTTGCCCGGTCACTGGCACTCCAGAAG
ACAGCGTGCCGGAACCGGCAGCTCTCACCTTTCTGTGACTTGTTCGGAATTAACTCCTCTGGATGGAAACTTCCATCTTACTTGGTTACA
TCACGGCTCTGGTTCAGATACAACTTCATGATTTTGCTACTATCATTTTTCACTTTTCAAAGAATTTAACCTATTTTACAGCAGTTCAGT
TCTGCTAGTGAGTAGTTTTCCTCTCCTACCTTCCTTCTAAAAACCTGATTCATGCACAGCGTTTGACACACATGGAGTCTGCCAGTGTGC

>44725_44725_16_LIMK2-RUFY1_LIMK2_chr22_31621805_ENST00000444929_RUFY1_chr5_179007948_ENST00000437570_length(amino acids)=466AA_BP=54
MLCPPPPPPHFRAPGTMSALAGEDVWRCPGCGDHIAPSQIWYRTVNETWHGSCFRHERITDVLDQKNYVEELNRHLSCTVGDLQTKIDGL
EKTNSKLQEELSAATDRICSLQEEQQQLREQNELIRERSEKSVEITKQDTKVELETYKQTRQGLDEMYSDVWKQLKEEKKVRLELEKELE
LQIGMKTEMEIAMKLLEKDTHEKQDTLVALRQQLEEVKAINLQMFHKAQNAESSLQQKNEAITSFEGKTNQVMSSMKQMEERLQHSERAR
QGAEERSHKLQQELGGRIGALQLQLSQLHEQCSSLEKELKSEKEQRQALQRELQHEKDTSSLLRMELQQVEGLKKELRELQDEKAELQKI
CEEQEQALQEMGLHLSQSKLKMEDIKEVNQALKGHAWLKDDEATHCRQCEKEFSISRRKHHCRNCGHIFCNTCSSNELALPSYPKPVRVC

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for LIMK2-RUFY1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneRUFY1chr22:31621805chr5:179007947ENST00000319449518615_625296.6666666666667709.0RAB4
TgeneRUFY1chr22:31621805chr5:179007947ENST00000377001519615_625296.6666666666667522.0RAB4
TgeneRUFY1chr22:31621805chr5:179007947ENST00000393438518615_625188.66666666666666601.0RAB4
TgeneRUFY1chr22:31621805chr5:179007947ENST00000437570417615_625188.66666666666666601.0RAB4
TgeneRUFY1chr22:31621805chr5:179007948ENST00000319449518615_625296.6666666666667709.0RAB4
TgeneRUFY1chr22:31621805chr5:179007948ENST00000377001519615_625296.6666666666667522.0RAB4
TgeneRUFY1chr22:31621805chr5:179007948ENST00000393438518615_625188.66666666666666601.0RAB4
TgeneRUFY1chr22:31621805chr5:179007948ENST00000437570417615_625188.66666666666666601.0RAB4


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


Top

Related Drugs for LIMK2-RUFY1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

Top

Related Diseases for LIMK2-RUFY1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource