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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ANKLE2-NHP2L1 (FusionGDB2 ID:4500) |
Fusion Gene Summary for ANKLE2-NHP2L1 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANKLE2-NHP2L1 | Fusion gene ID: 4500 | Hgene | Tgene | Gene symbol | ANKLE2 | NHP2L1 | Gene ID | 23141 | 4809 |
| Gene name | ankyrin repeat and LEM domain containing 2 | small nuclear ribonucleoprotein 13 | |
| Synonyms | KIAA0692|LEMD7|Lem4|MCPH16 | 15.5K|FA-1|FA1|NHP2L1|NHPX|OTK27|SNRNP15-5|SPAG12|SSFA1 | |
| Cytomap | 12q24.33 | 22q13.2 | |
| Type of gene | protein-coding | protein-coding | |
| Description | ankyrin repeat and LEM domain-containing protein 2LEM domain containing 7LEM domain-containing protein 4 | NHP2-like protein 1NHP2 non-histone chromosome protein 2-like 1SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)U4/U6.U5 tri-snRNP 15.5 kDa protein[U4/U6.U5] tri-snRNP 15.5 kD RNA binding proteinhigh mobility group-like nuclear protein 2 homo | |
| Modification date | 20200313 | 20200313 | |
| UniProtAcc | Q86XL3 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000337516, ENST00000357997, ENST00000539605, ENST00000542282, ENST00000542374, ENST00000542657, | ENST00000402458, ENST00000463675, ENST00000215956, ENST00000355257, ENST00000401959, | |
| Fusion gene scores | * DoF score | 8 X 7 X 7=392 | 5 X 3 X 5=75 |
| # samples | 9 | 6 | |
| ** MAII score | log2(9/392*10)=-2.12285674778553 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(6/75*10)=-0.321928094887362 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANKLE2 [Title/Abstract] AND NHP2L1 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ANKLE2(133324418)-NHP2L1(42076368), # samples:2 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ANKLE2 | GO:0007417 | central nervous system development | 25259927 |
| Hgene | ANKLE2 | GO:0035307 | positive regulation of protein dephosphorylation | 22770216 |
| Hgene | ANKLE2 | GO:0042326 | negative regulation of phosphorylation | 22770216 |
| Hgene | ANKLE2 | GO:0043066 | negative regulation of apoptotic process | 25259927 |
| Tgene | NHP2L1 | GO:0000398 | mRNA splicing, via spliceosome | 28781166 |
| Fusion gene breakpoints across ANKLE2 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across NHP2L1 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-BH-A0B7-01A | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| ChimerDB4 | BRCA | TCGA-BH-A0B7 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
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Fusion Gene ORF analysis for ANKLE2-NHP2L1 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-5UTR | ENST00000337516 | ENST00000402458 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000337516 | ENST00000402458 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000337516 | ENST00000463675 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000337516 | ENST00000463675 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000357997 | ENST00000402458 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000357997 | ENST00000402458 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000357997 | ENST00000463675 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000357997 | ENST00000463675 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000539605 | ENST00000402458 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000539605 | ENST00000402458 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000539605 | ENST00000463675 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| 5CDS-5UTR | ENST00000539605 | ENST00000463675 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000337516 | ENST00000215956 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000337516 | ENST00000215956 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000337516 | ENST00000355257 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000337516 | ENST00000355257 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000337516 | ENST00000401959 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000337516 | ENST00000401959 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000357997 | ENST00000215956 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000357997 | ENST00000215956 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000357997 | ENST00000355257 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000357997 | ENST00000355257 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000357997 | ENST00000401959 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000357997 | ENST00000401959 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000539605 | ENST00000215956 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000539605 | ENST00000215956 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000539605 | ENST00000355257 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000539605 | ENST00000355257 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000539605 | ENST00000401959 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| In-frame | ENST00000539605 | ENST00000401959 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542282 | ENST00000215956 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542282 | ENST00000215956 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542282 | ENST00000355257 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542282 | ENST00000355257 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542282 | ENST00000401959 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542282 | ENST00000401959 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542374 | ENST00000215956 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542374 | ENST00000215956 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542374 | ENST00000355257 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542374 | ENST00000355257 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542374 | ENST00000401959 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542374 | ENST00000401959 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542657 | ENST00000215956 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542657 | ENST00000215956 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542657 | ENST00000355257 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542657 | ENST00000355257 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542657 | ENST00000401959 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-3CDS | ENST00000542657 | ENST00000401959 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542282 | ENST00000402458 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542282 | ENST00000402458 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542282 | ENST00000463675 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542282 | ENST00000463675 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542374 | ENST00000402458 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542374 | ENST00000402458 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542374 | ENST00000463675 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542374 | ENST00000463675 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542657 | ENST00000402458 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542657 | ENST00000402458 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542657 | ENST00000463675 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - |
| intron-5UTR | ENST00000542657 | ENST00000463675 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000539605 | ANKLE2 | chr12 | 133324417 | - | ENST00000355257 | NHP2L1 | chr22 | 42076368 | - | 9116 | 7729 | 6670 | 8112 | 480 |
| ENST00000539605 | ANKLE2 | chr12 | 133324417 | - | ENST00000215956 | NHP2L1 | chr22 | 42076368 | - | 9092 | 7729 | 6670 | 8112 | 480 |
| ENST00000539605 | ANKLE2 | chr12 | 133324417 | - | ENST00000401959 | NHP2L1 | chr22 | 42076368 | - | 9079 | 7729 | 6670 | 8112 | 480 |
| ENST00000357997 | ANKLE2 | chr12 | 133324417 | - | ENST00000355257 | NHP2L1 | chr22 | 42076368 | - | 2707 | 1320 | 90 | 1703 | 537 |
| ENST00000357997 | ANKLE2 | chr12 | 133324417 | - | ENST00000215956 | NHP2L1 | chr22 | 42076368 | - | 2683 | 1320 | 90 | 1703 | 537 |
| ENST00000357997 | ANKLE2 | chr12 | 133324417 | - | ENST00000401959 | NHP2L1 | chr22 | 42076368 | - | 2670 | 1320 | 90 | 1703 | 537 |
| ENST00000337516 | ANKLE2 | chr12 | 133324417 | - | ENST00000355257 | NHP2L1 | chr22 | 42076368 | - | 2684 | 1297 | 67 | 1680 | 537 |
| ENST00000337516 | ANKLE2 | chr12 | 133324417 | - | ENST00000215956 | NHP2L1 | chr22 | 42076368 | - | 2660 | 1297 | 67 | 1680 | 537 |
| ENST00000337516 | ANKLE2 | chr12 | 133324417 | - | ENST00000401959 | NHP2L1 | chr22 | 42076368 | - | 2647 | 1297 | 67 | 1680 | 537 |
| ENST00000539605 | ANKLE2 | chr12 | 133324418 | - | ENST00000355257 | NHP2L1 | chr22 | 42076368 | - | 9116 | 7729 | 6670 | 8112 | 480 |
| ENST00000539605 | ANKLE2 | chr12 | 133324418 | - | ENST00000215956 | NHP2L1 | chr22 | 42076368 | - | 9092 | 7729 | 6670 | 8112 | 480 |
| ENST00000539605 | ANKLE2 | chr12 | 133324418 | - | ENST00000401959 | NHP2L1 | chr22 | 42076368 | - | 9079 | 7729 | 6670 | 8112 | 480 |
| ENST00000357997 | ANKLE2 | chr12 | 133324418 | - | ENST00000355257 | NHP2L1 | chr22 | 42076368 | - | 2707 | 1320 | 90 | 1703 | 537 |
| ENST00000357997 | ANKLE2 | chr12 | 133324418 | - | ENST00000215956 | NHP2L1 | chr22 | 42076368 | - | 2683 | 1320 | 90 | 1703 | 537 |
| ENST00000357997 | ANKLE2 | chr12 | 133324418 | - | ENST00000401959 | NHP2L1 | chr22 | 42076368 | - | 2670 | 1320 | 90 | 1703 | 537 |
| ENST00000337516 | ANKLE2 | chr12 | 133324418 | - | ENST00000355257 | NHP2L1 | chr22 | 42076368 | - | 2684 | 1297 | 67 | 1680 | 537 |
| ENST00000337516 | ANKLE2 | chr12 | 133324418 | - | ENST00000215956 | NHP2L1 | chr22 | 42076368 | - | 2660 | 1297 | 67 | 1680 | 537 |
| ENST00000337516 | ANKLE2 | chr12 | 133324418 | - | ENST00000401959 | NHP2L1 | chr22 | 42076368 | - | 2647 | 1297 | 67 | 1680 | 537 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000539605 | ENST00000355257 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - | 0.002695072 | 0.9973049 |
| ENST00000539605 | ENST00000215956 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - | 0.00258907 | 0.99741095 |
| ENST00000539605 | ENST00000401959 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - | 0.002870132 | 0.99712986 |
| ENST00000357997 | ENST00000355257 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - | 0.001797518 | 0.99820244 |
| ENST00000357997 | ENST00000215956 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - | 0.001913965 | 0.9980861 |
| ENST00000357997 | ENST00000401959 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - | 0.001880757 | 0.9981192 |
| ENST00000337516 | ENST00000355257 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - | 0.001749682 | 0.9982503 |
| ENST00000337516 | ENST00000215956 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - | 0.001863166 | 0.99813676 |
| ENST00000337516 | ENST00000401959 | ANKLE2 | chr12 | 133324417 | - | NHP2L1 | chr22 | 42076368 | - | 0.001828583 | 0.99817145 |
| ENST00000539605 | ENST00000355257 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - | 0.002695072 | 0.9973049 |
| ENST00000539605 | ENST00000215956 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - | 0.00258907 | 0.99741095 |
| ENST00000539605 | ENST00000401959 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - | 0.002870132 | 0.99712986 |
| ENST00000357997 | ENST00000355257 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - | 0.001797518 | 0.99820244 |
| ENST00000357997 | ENST00000215956 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - | 0.001913965 | 0.9980861 |
| ENST00000357997 | ENST00000401959 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - | 0.001880757 | 0.9981192 |
| ENST00000337516 | ENST00000355257 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - | 0.001749682 | 0.9982503 |
| ENST00000337516 | ENST00000215956 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - | 0.001863166 | 0.99813676 |
| ENST00000337516 | ENST00000401959 | ANKLE2 | chr12 | 133324418 | - | NHP2L1 | chr22 | 42076368 | - | 0.001828583 | 0.99817145 |
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Fusion Genomic Features for ANKLE2-NHP2L1 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ANKLE2-NHP2L1 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:133324418/chr22:42076368) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANKLE2 | . |
| FUNCTION: Involved in mitotic nuclear envelope reassembly by promoting dephosphorylation of BAF/BANF1 during mitotic exit (PubMed:22770216). Coordinates the control of BAF/BANF1 dephosphorylation by inhibiting VRK1 kinase and promoting dephosphorylation of BAF/BANF1 by protein phosphatase 2A (PP2A), thereby facilitating nuclear envelope assembly (PubMed:22770216). May regulate nuclear localization of VRK1 in non-dividing cells (PubMed:31735666). It is unclear whether it acts as a real PP2A regulatory subunit or whether it is involved in recruitment of the PP2A complex (PubMed:22770216). Involved in brain development (PubMed:25259927). {ECO:0000269|PubMed:22770216, ECO:0000269|PubMed:25259927, ECO:0000269|PubMed:31735666}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 69_113 | 410 | 649.0 | Domain | LEM |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 69_113 | 410 | 939.0 | Domain | LEM |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 69_113 | 410 | 649.0 | Domain | LEM |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 69_113 | 410 | 939.0 | Domain | LEM |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 1_12 | 410 | 649.0 | Topological domain | Lumenal |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 1_12 | 410 | 939.0 | Topological domain | Lumenal |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 1_12 | 410 | 649.0 | Topological domain | Lumenal |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 1_12 | 410 | 939.0 | Topological domain | Lumenal |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 13_32 | 410 | 649.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 13_32 | 410 | 939.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 13_32 | 410 | 649.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 13_32 | 410 | 939.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 69_113 | 0 | 294.0 | Domain | LEM |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 69_113 | 0 | 294.0 | Domain | LEM |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 69_113 | 0 | 294.0 | Domain | LEM |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 69_113 | 0 | 294.0 | Domain | LEM |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 411_440 | 410 | 649.0 | Repeat | Note=ANK |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 411_440 | 410 | 939.0 | Repeat | Note=ANK |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 411_440 | 0 | 294.0 | Repeat | Note=ANK |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 411_440 | 0 | 294.0 | Repeat | Note=ANK |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 411_440 | 410 | 649.0 | Repeat | Note=ANK |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 411_440 | 410 | 939.0 | Repeat | Note=ANK |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 411_440 | 0 | 294.0 | Repeat | Note=ANK |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 411_440 | 0 | 294.0 | Repeat | Note=ANK |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 33_938 | 410 | 649.0 | Topological domain | Cytoplasmic |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 33_938 | 410 | 939.0 | Topological domain | Cytoplasmic |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 1_12 | 0 | 294.0 | Topological domain | Lumenal |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 33_938 | 0 | 294.0 | Topological domain | Cytoplasmic |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 1_12 | 0 | 294.0 | Topological domain | Lumenal |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 33_938 | 0 | 294.0 | Topological domain | Cytoplasmic |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000337516 | - | 5 | 11 | 33_938 | 410 | 649.0 | Topological domain | Cytoplasmic |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000357997 | - | 5 | 13 | 33_938 | 410 | 939.0 | Topological domain | Cytoplasmic |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 1_12 | 0 | 294.0 | Topological domain | Lumenal |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 33_938 | 0 | 294.0 | Topological domain | Cytoplasmic |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 1_12 | 0 | 294.0 | Topological domain | Lumenal |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 33_938 | 0 | 294.0 | Topological domain | Cytoplasmic |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 13_32 | 0 | 294.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | ANKLE2 | chr12:133324417 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 13_32 | 0 | 294.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542282 | - | 1 | 3 | 13_32 | 0 | 294.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
| Hgene | ANKLE2 | chr12:133324418 | chr22:42076368 | ENST00000542657 | - | 1 | 4 | 13_32 | 0 | 294.0 | Transmembrane | Helical%3B Signal-anchor for type III membrane protein |
Top |
Fusion Gene Sequence for ANKLE2-NHP2L1 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >4500_4500_1_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000337516_NHP2L1_chr22_42076368_ENST00000215956_length(transcript)=2660nt_BP=1297nt GCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGC GGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCG GCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCAGGTGAAATGACAATGGATGCTCT GTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTAC AAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCAC AGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGG TTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGC TGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGT TTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAA ATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAA TGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGA CCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGG CTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCA GCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTA CGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCAC CAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGG CATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCC CTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGG CTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGC CAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAA ATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCAT CCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAG CTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCAT TGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATT TGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTG ATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGG CAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCA TGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGG GACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACAT >4500_4500_1_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000337516_NHP2L1_chr22_42076368_ENST00000215956_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_2_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000337516_NHP2L1_chr22_42076368_ENST00000355257_length(transcript)=2684nt_BP=1297nt GCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGC GGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCG GCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCAGGTGAAATGACAATGGATGCTCT GTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTAC AAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCAC AGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGG TTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGC TGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGT TTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAA ATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAA TGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGA CCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGG CTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCA GCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTA CGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCAC CAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGG CATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCC CTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGG CTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGC CAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAA ATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCAT CCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAG CTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCAT TGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATT TGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTG ATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGG CAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCA TGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGG GACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACAT >4500_4500_2_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000337516_NHP2L1_chr22_42076368_ENST00000355257_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_3_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000337516_NHP2L1_chr22_42076368_ENST00000401959_length(transcript)=2647nt_BP=1297nt GCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGC GGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCG GCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCAGGTGAAATGACAATGGATGCTCT GTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTAC AAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCAC AGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGG TTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGC TGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGT TTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAA ATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAA TGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGA CCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGG CTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCA GCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTA CGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCAC CAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGG CATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCC CTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGG CTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGC CAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAA ATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCAT CCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAG CTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCAT TGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATT TGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTG ATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGG CAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCA TGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGG GACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACAT >4500_4500_3_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000337516_NHP2L1_chr22_42076368_ENST00000401959_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_4_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000357997_NHP2L1_chr22_42076368_ENST00000215956_length(transcript)=2683nt_BP=1320nt AGGCAGGGCGCGGGCAGCCCGGCGCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCG ATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGG CTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCA GGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAA TGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTC TACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGT TTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCT AGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCA GCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTT TCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTG AAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGT TACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGG AGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAA GAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCC ATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTAT CCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAG GCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTG CTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCC TGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGT GGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCT ATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCC TCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAA AGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTG TGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTG CTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCC TGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGA GATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCA GAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGA AACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGG >4500_4500_4_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000357997_NHP2L1_chr22_42076368_ENST00000215956_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_5_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000357997_NHP2L1_chr22_42076368_ENST00000355257_length(transcript)=2707nt_BP=1320nt AGGCAGGGCGCGGGCAGCCCGGCGCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCG ATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGG CTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCA GGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAA TGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTC TACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGT TTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCT AGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCA GCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTT TCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTG AAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGT TACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGG AGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAA GAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCC ATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTAT CCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAG GCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTG CTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCC TGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGT GGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCT ATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCC TCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAA AGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTG TGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTG CTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCC TGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGA GATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCA GAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGA AACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGG GTCAGATGTACTCTCTGTCACATGAGGAGAGTGCTAGTTCATGTGTTCTCCATTCTTGTGAGCATCCTAATAAATCTGTTCCATTTTGAT >4500_4500_5_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000357997_NHP2L1_chr22_42076368_ENST00000355257_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_6_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000357997_NHP2L1_chr22_42076368_ENST00000401959_length(transcript)=2670nt_BP=1320nt AGGCAGGGCGCGGGCAGCCCGGCGCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCG ATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGG CTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCA GGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAA TGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTC TACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGT TTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCT AGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCA GCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTT TCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTG AAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGT TACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGG AGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAA GAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCC ATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTAT CCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAG GCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTG CTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCC TGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGT GGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCT ATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCC TCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAA AGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTG TGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTG CTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCC TGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGA GATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCA GAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGA AACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGG >4500_4500_6_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000357997_NHP2L1_chr22_42076368_ENST00000401959_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_7_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000539605_NHP2L1_chr22_42076368_ENST00000215956_length(transcript)=9092nt_BP=7729nt GCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTG ATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCC GCCGCCCCCGCCTCAGGTAAGGCCCAGGCGGTCGCTGGGTCCCCGCACCCTGGCCCCTTCCCCGCCCCGACGCCCTCCTCGGGCCTGGGG TCCCGGCCGCGCCCCTGGAGCCGGCAGCAGTTGGGCGAGGCGGCCGGGGAAACCAGGGCCGGTCGGGAAAGGCCATTCCGGCCGCGGAAA GGGCAGTTGCGGGGACTTGGCTTCCCGGGCCGGGGGCGGAGGGGCCACGCCGGGTTCGGGGGTGAGAGCTTTCCCGGGCCCTGGAGCAGC CTCCGGGGAAGGCGGCGGGGGCCCGGCGAGGCGTTAGCGGAGACTCTTGCTGCGGTCTCTCGAGACCTGGGGAGGGATGGCCCAAAGGAG GGCGGCGCGGGGAGGAAACCCCTGGGTCCCGGATGTGTTTGGAACGTGAAGCCATTGCGGTTACTGGTCATGGAACATAAGGCAGAGACG GAAAAGGCAAATGTAACTCAGGGGTTTGGGGCCAGAGGAAGAGGGAGAAGGTGGCCATTTATTGCTTTGCGGTAGACTGTCGGGTCTGGG TGATGTGGAGATCAGAGGTGGGTTTTGGTCGTTTTAAGTTTGAGGTAACTGATACAGTGAACTGTGTATTTCAGCTCCATCCCCTTTTCC TGGCATACAACTCTTGAAATCCCGGGAACCTCCAAAGTGATGTCTTTTGTAGGCTGAGTGGACTGGTGGCCGGCAGCCCCTAGGGAGCTT CTGGATGGGGCTGGTCGCAGGAAAGACCAAGGCAGGGTTAGAGGTTCTGGGGACTTTCAGCCCCACCCCCAACCTCTGGGGAGGAGAGAG GGGTGAAGGTTGCGTTGATCACCAGTGGCTGATGAATCACGCCTGTGAAATGAAGTTCCTGTAAAAACCCAAAAGGGCTGGGTTCAGGGA GCTTCCAGATAGTACGTGGGGGTTCCTGGAGGCGGTGCCCAGAGAGGCCCTGAATTTCCAAGCGCTTCCCCCCGGTTTTACGTCACGCAT CTCTTCACCTGTATTCTTTGTAATCCTTTATACTCTGCTGGTAAGTGTAAGTAAAACATGTCTGTGAGTTCGGGAGCCACTCTAGCAAAT TACCGCAACCTGAGGAGGTCACCGGGTTACGCCCCGTCGGTCCCAAGCGCAGGTCAAACAACCTGGGCACTGGAAGTGGGGGGCAGTCTT GCGGGGCTGAGCCGTTAACCTGTGGGGGTCTGCTGGTATCTCCAGGAAGACGCTGTCAGAATAGATGACTGAATTAGGATGACAGACGAC ACCCAGCCTGTGTCCACTGCAGAACTGACGACCTGCGTGATTTGTGGGGAGAAAATCCCCACATACCTGGTGTCCGAAGCATGTTGCAAG ACTAGTGGGAGAAACTGAGTTTGTTTTTACTCTAAATTGTCAGACTGTTAGTCACTGCGGAGAGGTGCTTTCTGATGATTGAGTGGGGAT TCCTGTCCAATTGTGTGAGTTTGTGTCTCGGCCCTACCACTTTTTTTTTTTTTTTTTTTTGAAATGTAGTCTCGCCCTGTGGCCCAGGCT GGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCATCAGCCTCCCGAGTAGCTGGGAT TACAGGCGCCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAATAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGAATTCCT GACCTCAGGTGATCCACCTGCCTCAGCTTCCCAAAATGCTGGGATTACAGGTGTGAGCCATCGCACCGGGCCCTACCACTTATTGCTGTG GGCTTAACCTGTTTTCAGCCTGCTCTTTTAGGAATGGGGATGATAGTGATACCTGGTTAGGCTTTTTTGGGAGTTGGGTAAGTGCAGCAC TTGGTATGTGTTAAGCACCTCTGAGTGCTGTTACTGTCACCAGCGGCATCATCCAGGCAGAGCTGCGGACAAGGTGGCGGCGGGTGAGGG TGGTGTTTTGAGAATGGCTGAAATAAAAAAATACTGATTTATTTTATATAAAAATATGTTTTTATATATGATGTATAATATACGTATATC ATGGCATATGATACGTGTATATCATATAGCACATATAGTATACATATATATAGTCAGCAGAGATTTAGAGAAACTGGGCCTCGTGCATTG CAGGTGGGGACGGTAAGTGGTGCAGCTACTCTGGGAATCAGCCTGGCAGGTTTTTAGGAAGTTAAACCTGCCCTGCATTCCTGAGCTTTT ATTAGACAAATGAAAACTATTTTCACACAAAAACCCATATTTAATGTTCATAGCAACTTTATTTGTAATTACCAGAAACTGAAATAACTC AAATGGTTAAACTTGCACACTGATACCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCAT GATCCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCGTGAT CCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCC ACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACACTGCGTGATCCACT CTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCACTCTGCCACGTGGGTGGATCTCAAGGGCATTATGCTGAATAGGAAAAG CCAGTCTCAAAAGTTGTGTACTTGGCCGGTTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACAAG GTCAGGAGTTCAAGATCAGCCTGGCCAACATGGTGAGGCAGTCTCCACTAAAAATACAAAAAAATAGCGGGGCGTGGTGGCAGGTACCTG TAATCCCAGCTACTCGGGAGGCTGAGGCAGCAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCAGAGATCGTGCCACTGCACT CCAGCCTGGGCGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAATTGTTAATGGAACATTATAACCCAGTGTTCAGACCTAGCTGTTTC TCACATCTTTACCCATCGATCTGTCAAAGACCTTGTGATCATACTGATACTTCCAATTTCAATGCGACGTCCGCGGGTTTATTCTTTTTT TTTTAGGTGGAGTCTCACTCTGTTGTCCAGGCTGGAGACTCACTGCAACCTCTGCCTGCCCAGTTCAAGCGATTCTCCCACCTAGCCTGC TGAGTAGCTGGGATGACAGGTGCATGCCACCATGCCTGGCTAATTTTTGTGTTTTTAGTAGACACCTGGTTTCATCATGTTGGCCAGGCT GGTCTCAAACACCTGACCTCAAATGATCCATGCACCTTGGCCTCCCAAAGTGCTGGGATTACCAGCATGAGCCACCGTGTCCGGCTCCCT GGCTTTATTCTAATGCAAGAGTCAGTAAACTGTGGTCCAAACTGGCCCCCACCTATTTTCCTTAGTAAAGTTTTATTGGAATACAACCAT ACCCTTTTGTTTATGTATATCTGTGGCTGTTCTTTTTTTTTTTTTTTTTGGAGACGGGGTCTTGCTCTGTTGCCCAGGTTGGAGTGCAGT GGCACAAACAGGGCTCACTGCATCCTCAAACTCTTAGGCTTAATTTATCCTCCTTCCTCAGCCCCCCAAGTAGTTGGAACCACAGGTGCA CGTCACCACACTCAGCTAATTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGCCGCCATCTCTGCTCACT GCAAGTTCTGCCCCCTGGGTTCACACCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCATGGCCGGCTAA TTTTTTAGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTTGCCAGGATAGTCTCAATCTCCTGACCTCATGATCCACCTGCCTCGGCCT CCCAAAGTGCTGGGATTACAGGCATGAGTCACCGCGCCCAGCCATCAGATAATTTTTAAAGTTTTTGTAGAAAGGGTGTCGCTGTGTTAC CCAGGCTGGTCTTGAACTCCTGGGCTCAAGTGATCTTCCCGCCTCGGCCTCCCCAAGCGCTGGGGTGACAGGTGTGAGCCGCCACACGCG GCCTGTGGCTGTTCTGAGCACTCACGTGGCCTTTGGCTCATAGAGTCTGAGATGCTTACTCTCTCGCCCTTTACAGGAATCGTTTGCTGA AACCCTGTTCTCACTCCCACTTTCCTTTCTGTCATTGAGAGTCCTGGCTCTCATCAGCCACCGTGTATTCCAATTATTTGCTTTGCCCTA GAGTCCACAGAAAATAGCTTTAGGTGTGTTAACCTATACCATTGTGAAAACATCTACTGCCTAGAGCCTGTTCACACGGTAATGGTGCAC AGTCCTTTTTGTCTTTCTCCTTAGAGCACCTAGTCACTCACTGTTTTCCAAAGTTACGTAGGTTAGCTTCCCCTGTGTTACTCACTTGTA ATACAGTTAGGTGCATTTCTTCTGGCTAGTATTCCATGTGGGTGTCTCCCCCATCTTTTTGTTTATTTACTTATTTCTTTTTTTTTTGTT TTTTTTGTTGTTGTTGTTTTATTGAGGTGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGTAGTGGTGCGATCTCGGCTCACTGTGACCTC TGCCTCCTGGGTTCCAGCGAGTCTCCTGCCTCAGGTTCCCGAGTAGCTGGGATTACAGGTGCCCGCCACTGCGCCTGTCTAATTTTTGTA TTTTTTTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGGTCTCGAACTGCTGACCTCGTGATCCACCCACCTCGGTCTCCCAA AGTGCTGCGATTACAGGCGTGAGCCACCGCACCCGGCTTTACTTATTTGAGTATGTAAATCACGAACATGTTTTTAAAAGTCAGAACCCT GTAGAAACTTAAATTCAGATGTATTACTCCCCCCCGCCATCTTTTTTTTTGTTGTTGTTGTTGAGACAGGGTCTGATTCTGTCACCCAGG CTGGAGTGCAGGGTTGCCATCTCAGCTCGTGGTGGCATCCACCTCCCAGGCTCAAGTGATCCTCCTGCCTCAGCCCCCTGAGTAGCTGGG GCTGTAGGTGTGCACTACTATGCTCGGGTAATTTTTTTTTTTTGAAACAAGGTCTTGCTCTTGTCCCCTAGGCTGGAGTGCAGTGGCGTG ATTTCGGCTCACTGCAACCTCCACCTACTGGGTTCAAGCAATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGGTTACAGGCATGTACCAC CACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTG CCTGCCTCCCAAAGAATACAACGGGCTGGGCATGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGTTGGGAGTTCAAGACCAGCCT GACCAACATGGAGAAACCCCGTCTCTACTAAAAGTACAAAATTAGCTGGGCGTGGTGGTGCACGCCTGTAATCCCAGCTACTCGGGAGGC TTGAGGCAGGAGAACCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGCCTGGTGACAGAG CGAGACTCCGTCTCAAAAAGAAAAAAGGCTCACGCCTGTAATCCAAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCGGGAG TGCAAGACCAACCTGGCCAACATGGTGAAACCCCGTCTCTCCTAAAAATACAAAAATTAGCTAGGTGTGATTCCAGGCGCCTGTAGTCCC AGCTACTTGGGAGGCTGAGGCTGGAGAATCACTTGAACTCAGGAGGTAGAGGTTGCAGTGAGCTGCGATAGCACCACTGCACTCCAGCCT GTGCGACAGAGGGAGACACCATCTCGAAAAAAAAAAGAAAAATTCTTTTTTTTTTTTTGAGCTGGAGTTTCGCTCTTGTTGTCTAAGCTG GAGTGCAGGGGTGTGATCTCGGCTAATTGCAGCCTCCGCCTCCTGGGTTCAAGCGATTCTCCAGCCTCAGCCTCCCAAGTAGCTGGGATT ACAGGCATCCGCCACCACACCCGGCTAATTTTTTGTATTTTCAGTAGAGACGTGGTTTCACCATGTTGGCCGGGCTGGTCTCGAACTCCT GACCTCAGATGATCCGCCCGCCTCAGCCTCCCAAAATGCTGGGATTACAGGCGTGAGCCACCGCGTCCAGCCAAGAAAAAAAGTTTTTAA TGAAAGAAACAGAAACTGATGCCATTATATAATGAACCCTAGTACCCATCACCCAGCTTCAGCAGGTGTTAGTATTTTGTGACTCTTTGA TTTTTTTGTCTTGGGCCTAGGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAAT CGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGG AGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAA CCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAA GACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCC AGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGG GTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTC CTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAA CAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACAC CTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGT GATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTA CCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGA TGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCT TCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGAT CATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGT CTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAG GCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTA GTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTT GCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCA GGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCT TCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGT GATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTG TCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAG GGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGA GTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAG AGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCT GTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACATGAGGAGAGTGCTAGTTCATGTGTTCTCCATTCTTGTGAGCATCCTAAT >4500_4500_7_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000539605_NHP2L1_chr22_42076368_ENST00000215956_length(amino acids)=480AA_BP=353 MGLGEMTMDALLARLKLLNPDDLREEIVKAGLKCGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTD QAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPPSDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRF KAFSTREDAEKFARGICDYFPSPSKTSLPLSPVKTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSD LIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNP KAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRP -------------------------------------------------------------- >4500_4500_8_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000539605_NHP2L1_chr22_42076368_ENST00000355257_length(transcript)=9116nt_BP=7729nt GCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTG ATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCC GCCGCCCCCGCCTCAGGTAAGGCCCAGGCGGTCGCTGGGTCCCCGCACCCTGGCCCCTTCCCCGCCCCGACGCCCTCCTCGGGCCTGGGG TCCCGGCCGCGCCCCTGGAGCCGGCAGCAGTTGGGCGAGGCGGCCGGGGAAACCAGGGCCGGTCGGGAAAGGCCATTCCGGCCGCGGAAA GGGCAGTTGCGGGGACTTGGCTTCCCGGGCCGGGGGCGGAGGGGCCACGCCGGGTTCGGGGGTGAGAGCTTTCCCGGGCCCTGGAGCAGC CTCCGGGGAAGGCGGCGGGGGCCCGGCGAGGCGTTAGCGGAGACTCTTGCTGCGGTCTCTCGAGACCTGGGGAGGGATGGCCCAAAGGAG GGCGGCGCGGGGAGGAAACCCCTGGGTCCCGGATGTGTTTGGAACGTGAAGCCATTGCGGTTACTGGTCATGGAACATAAGGCAGAGACG GAAAAGGCAAATGTAACTCAGGGGTTTGGGGCCAGAGGAAGAGGGAGAAGGTGGCCATTTATTGCTTTGCGGTAGACTGTCGGGTCTGGG TGATGTGGAGATCAGAGGTGGGTTTTGGTCGTTTTAAGTTTGAGGTAACTGATACAGTGAACTGTGTATTTCAGCTCCATCCCCTTTTCC TGGCATACAACTCTTGAAATCCCGGGAACCTCCAAAGTGATGTCTTTTGTAGGCTGAGTGGACTGGTGGCCGGCAGCCCCTAGGGAGCTT CTGGATGGGGCTGGTCGCAGGAAAGACCAAGGCAGGGTTAGAGGTTCTGGGGACTTTCAGCCCCACCCCCAACCTCTGGGGAGGAGAGAG GGGTGAAGGTTGCGTTGATCACCAGTGGCTGATGAATCACGCCTGTGAAATGAAGTTCCTGTAAAAACCCAAAAGGGCTGGGTTCAGGGA GCTTCCAGATAGTACGTGGGGGTTCCTGGAGGCGGTGCCCAGAGAGGCCCTGAATTTCCAAGCGCTTCCCCCCGGTTTTACGTCACGCAT CTCTTCACCTGTATTCTTTGTAATCCTTTATACTCTGCTGGTAAGTGTAAGTAAAACATGTCTGTGAGTTCGGGAGCCACTCTAGCAAAT TACCGCAACCTGAGGAGGTCACCGGGTTACGCCCCGTCGGTCCCAAGCGCAGGTCAAACAACCTGGGCACTGGAAGTGGGGGGCAGTCTT GCGGGGCTGAGCCGTTAACCTGTGGGGGTCTGCTGGTATCTCCAGGAAGACGCTGTCAGAATAGATGACTGAATTAGGATGACAGACGAC ACCCAGCCTGTGTCCACTGCAGAACTGACGACCTGCGTGATTTGTGGGGAGAAAATCCCCACATACCTGGTGTCCGAAGCATGTTGCAAG ACTAGTGGGAGAAACTGAGTTTGTTTTTACTCTAAATTGTCAGACTGTTAGTCACTGCGGAGAGGTGCTTTCTGATGATTGAGTGGGGAT TCCTGTCCAATTGTGTGAGTTTGTGTCTCGGCCCTACCACTTTTTTTTTTTTTTTTTTTTGAAATGTAGTCTCGCCCTGTGGCCCAGGCT GGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCATCAGCCTCCCGAGTAGCTGGGAT TACAGGCGCCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAATAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGAATTCCT GACCTCAGGTGATCCACCTGCCTCAGCTTCCCAAAATGCTGGGATTACAGGTGTGAGCCATCGCACCGGGCCCTACCACTTATTGCTGTG GGCTTAACCTGTTTTCAGCCTGCTCTTTTAGGAATGGGGATGATAGTGATACCTGGTTAGGCTTTTTTGGGAGTTGGGTAAGTGCAGCAC TTGGTATGTGTTAAGCACCTCTGAGTGCTGTTACTGTCACCAGCGGCATCATCCAGGCAGAGCTGCGGACAAGGTGGCGGCGGGTGAGGG TGGTGTTTTGAGAATGGCTGAAATAAAAAAATACTGATTTATTTTATATAAAAATATGTTTTTATATATGATGTATAATATACGTATATC ATGGCATATGATACGTGTATATCATATAGCACATATAGTATACATATATATAGTCAGCAGAGATTTAGAGAAACTGGGCCTCGTGCATTG CAGGTGGGGACGGTAAGTGGTGCAGCTACTCTGGGAATCAGCCTGGCAGGTTTTTAGGAAGTTAAACCTGCCCTGCATTCCTGAGCTTTT ATTAGACAAATGAAAACTATTTTCACACAAAAACCCATATTTAATGTTCATAGCAACTTTATTTGTAATTACCAGAAACTGAAATAACTC AAATGGTTAAACTTGCACACTGATACCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCAT GATCCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCGTGAT CCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCC ACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACACTGCGTGATCCACT CTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCACTCTGCCACGTGGGTGGATCTCAAGGGCATTATGCTGAATAGGAAAAG CCAGTCTCAAAAGTTGTGTACTTGGCCGGTTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACAAG GTCAGGAGTTCAAGATCAGCCTGGCCAACATGGTGAGGCAGTCTCCACTAAAAATACAAAAAAATAGCGGGGCGTGGTGGCAGGTACCTG TAATCCCAGCTACTCGGGAGGCTGAGGCAGCAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCAGAGATCGTGCCACTGCACT CCAGCCTGGGCGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAATTGTTAATGGAACATTATAACCCAGTGTTCAGACCTAGCTGTTTC TCACATCTTTACCCATCGATCTGTCAAAGACCTTGTGATCATACTGATACTTCCAATTTCAATGCGACGTCCGCGGGTTTATTCTTTTTT TTTTAGGTGGAGTCTCACTCTGTTGTCCAGGCTGGAGACTCACTGCAACCTCTGCCTGCCCAGTTCAAGCGATTCTCCCACCTAGCCTGC TGAGTAGCTGGGATGACAGGTGCATGCCACCATGCCTGGCTAATTTTTGTGTTTTTAGTAGACACCTGGTTTCATCATGTTGGCCAGGCT GGTCTCAAACACCTGACCTCAAATGATCCATGCACCTTGGCCTCCCAAAGTGCTGGGATTACCAGCATGAGCCACCGTGTCCGGCTCCCT GGCTTTATTCTAATGCAAGAGTCAGTAAACTGTGGTCCAAACTGGCCCCCACCTATTTTCCTTAGTAAAGTTTTATTGGAATACAACCAT ACCCTTTTGTTTATGTATATCTGTGGCTGTTCTTTTTTTTTTTTTTTTTGGAGACGGGGTCTTGCTCTGTTGCCCAGGTTGGAGTGCAGT GGCACAAACAGGGCTCACTGCATCCTCAAACTCTTAGGCTTAATTTATCCTCCTTCCTCAGCCCCCCAAGTAGTTGGAACCACAGGTGCA CGTCACCACACTCAGCTAATTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGCCGCCATCTCTGCTCACT GCAAGTTCTGCCCCCTGGGTTCACACCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCATGGCCGGCTAA TTTTTTAGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTTGCCAGGATAGTCTCAATCTCCTGACCTCATGATCCACCTGCCTCGGCCT CCCAAAGTGCTGGGATTACAGGCATGAGTCACCGCGCCCAGCCATCAGATAATTTTTAAAGTTTTTGTAGAAAGGGTGTCGCTGTGTTAC CCAGGCTGGTCTTGAACTCCTGGGCTCAAGTGATCTTCCCGCCTCGGCCTCCCCAAGCGCTGGGGTGACAGGTGTGAGCCGCCACACGCG GCCTGTGGCTGTTCTGAGCACTCACGTGGCCTTTGGCTCATAGAGTCTGAGATGCTTACTCTCTCGCCCTTTACAGGAATCGTTTGCTGA AACCCTGTTCTCACTCCCACTTTCCTTTCTGTCATTGAGAGTCCTGGCTCTCATCAGCCACCGTGTATTCCAATTATTTGCTTTGCCCTA GAGTCCACAGAAAATAGCTTTAGGTGTGTTAACCTATACCATTGTGAAAACATCTACTGCCTAGAGCCTGTTCACACGGTAATGGTGCAC AGTCCTTTTTGTCTTTCTCCTTAGAGCACCTAGTCACTCACTGTTTTCCAAAGTTACGTAGGTTAGCTTCCCCTGTGTTACTCACTTGTA ATACAGTTAGGTGCATTTCTTCTGGCTAGTATTCCATGTGGGTGTCTCCCCCATCTTTTTGTTTATTTACTTATTTCTTTTTTTTTTGTT TTTTTTGTTGTTGTTGTTTTATTGAGGTGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGTAGTGGTGCGATCTCGGCTCACTGTGACCTC TGCCTCCTGGGTTCCAGCGAGTCTCCTGCCTCAGGTTCCCGAGTAGCTGGGATTACAGGTGCCCGCCACTGCGCCTGTCTAATTTTTGTA TTTTTTTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGGTCTCGAACTGCTGACCTCGTGATCCACCCACCTCGGTCTCCCAA AGTGCTGCGATTACAGGCGTGAGCCACCGCACCCGGCTTTACTTATTTGAGTATGTAAATCACGAACATGTTTTTAAAAGTCAGAACCCT GTAGAAACTTAAATTCAGATGTATTACTCCCCCCCGCCATCTTTTTTTTTGTTGTTGTTGTTGAGACAGGGTCTGATTCTGTCACCCAGG CTGGAGTGCAGGGTTGCCATCTCAGCTCGTGGTGGCATCCACCTCCCAGGCTCAAGTGATCCTCCTGCCTCAGCCCCCTGAGTAGCTGGG GCTGTAGGTGTGCACTACTATGCTCGGGTAATTTTTTTTTTTTGAAACAAGGTCTTGCTCTTGTCCCCTAGGCTGGAGTGCAGTGGCGTG ATTTCGGCTCACTGCAACCTCCACCTACTGGGTTCAAGCAATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGGTTACAGGCATGTACCAC CACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTG CCTGCCTCCCAAAGAATACAACGGGCTGGGCATGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGTTGGGAGTTCAAGACCAGCCT GACCAACATGGAGAAACCCCGTCTCTACTAAAAGTACAAAATTAGCTGGGCGTGGTGGTGCACGCCTGTAATCCCAGCTACTCGGGAGGC TTGAGGCAGGAGAACCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGCCTGGTGACAGAG CGAGACTCCGTCTCAAAAAGAAAAAAGGCTCACGCCTGTAATCCAAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCGGGAG TGCAAGACCAACCTGGCCAACATGGTGAAACCCCGTCTCTCCTAAAAATACAAAAATTAGCTAGGTGTGATTCCAGGCGCCTGTAGTCCC AGCTACTTGGGAGGCTGAGGCTGGAGAATCACTTGAACTCAGGAGGTAGAGGTTGCAGTGAGCTGCGATAGCACCACTGCACTCCAGCCT GTGCGACAGAGGGAGACACCATCTCGAAAAAAAAAAGAAAAATTCTTTTTTTTTTTTTGAGCTGGAGTTTCGCTCTTGTTGTCTAAGCTG GAGTGCAGGGGTGTGATCTCGGCTAATTGCAGCCTCCGCCTCCTGGGTTCAAGCGATTCTCCAGCCTCAGCCTCCCAAGTAGCTGGGATT ACAGGCATCCGCCACCACACCCGGCTAATTTTTTGTATTTTCAGTAGAGACGTGGTTTCACCATGTTGGCCGGGCTGGTCTCGAACTCCT GACCTCAGATGATCCGCCCGCCTCAGCCTCCCAAAATGCTGGGATTACAGGCGTGAGCCACCGCGTCCAGCCAAGAAAAAAAGTTTTTAA TGAAAGAAACAGAAACTGATGCCATTATATAATGAACCCTAGTACCCATCACCCAGCTTCAGCAGGTGTTAGTATTTTGTGACTCTTTGA TTTTTTTGTCTTGGGCCTAGGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAAT CGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGG AGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAA CCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAA GACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCC AGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGG GTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTC CTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAA CAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACAC CTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGT GATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTA CCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGA TGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCT TCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGAT CATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGT CTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAG GCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTA GTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTT GCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCA GGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCT TCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGT GATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTG TCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAG GGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGA GTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAG AGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCT GTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACATGAGGAGAGTGCTAGTTCATGTGTTCTCCATTCTTGTGAGCATCCTAAT >4500_4500_8_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000539605_NHP2L1_chr22_42076368_ENST00000355257_length(amino acids)=480AA_BP=353 MGLGEMTMDALLARLKLLNPDDLREEIVKAGLKCGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTD QAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPPSDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRF KAFSTREDAEKFARGICDYFPSPSKTSLPLSPVKTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSD LIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNP KAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRP -------------------------------------------------------------- >4500_4500_9_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000539605_NHP2L1_chr22_42076368_ENST00000401959_length(transcript)=9079nt_BP=7729nt GCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTG ATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCC GCCGCCCCCGCCTCAGGTAAGGCCCAGGCGGTCGCTGGGTCCCCGCACCCTGGCCCCTTCCCCGCCCCGACGCCCTCCTCGGGCCTGGGG TCCCGGCCGCGCCCCTGGAGCCGGCAGCAGTTGGGCGAGGCGGCCGGGGAAACCAGGGCCGGTCGGGAAAGGCCATTCCGGCCGCGGAAA GGGCAGTTGCGGGGACTTGGCTTCCCGGGCCGGGGGCGGAGGGGCCACGCCGGGTTCGGGGGTGAGAGCTTTCCCGGGCCCTGGAGCAGC CTCCGGGGAAGGCGGCGGGGGCCCGGCGAGGCGTTAGCGGAGACTCTTGCTGCGGTCTCTCGAGACCTGGGGAGGGATGGCCCAAAGGAG GGCGGCGCGGGGAGGAAACCCCTGGGTCCCGGATGTGTTTGGAACGTGAAGCCATTGCGGTTACTGGTCATGGAACATAAGGCAGAGACG GAAAAGGCAAATGTAACTCAGGGGTTTGGGGCCAGAGGAAGAGGGAGAAGGTGGCCATTTATTGCTTTGCGGTAGACTGTCGGGTCTGGG TGATGTGGAGATCAGAGGTGGGTTTTGGTCGTTTTAAGTTTGAGGTAACTGATACAGTGAACTGTGTATTTCAGCTCCATCCCCTTTTCC TGGCATACAACTCTTGAAATCCCGGGAACCTCCAAAGTGATGTCTTTTGTAGGCTGAGTGGACTGGTGGCCGGCAGCCCCTAGGGAGCTT CTGGATGGGGCTGGTCGCAGGAAAGACCAAGGCAGGGTTAGAGGTTCTGGGGACTTTCAGCCCCACCCCCAACCTCTGGGGAGGAGAGAG GGGTGAAGGTTGCGTTGATCACCAGTGGCTGATGAATCACGCCTGTGAAATGAAGTTCCTGTAAAAACCCAAAAGGGCTGGGTTCAGGGA GCTTCCAGATAGTACGTGGGGGTTCCTGGAGGCGGTGCCCAGAGAGGCCCTGAATTTCCAAGCGCTTCCCCCCGGTTTTACGTCACGCAT CTCTTCACCTGTATTCTTTGTAATCCTTTATACTCTGCTGGTAAGTGTAAGTAAAACATGTCTGTGAGTTCGGGAGCCACTCTAGCAAAT TACCGCAACCTGAGGAGGTCACCGGGTTACGCCCCGTCGGTCCCAAGCGCAGGTCAAACAACCTGGGCACTGGAAGTGGGGGGCAGTCTT GCGGGGCTGAGCCGTTAACCTGTGGGGGTCTGCTGGTATCTCCAGGAAGACGCTGTCAGAATAGATGACTGAATTAGGATGACAGACGAC ACCCAGCCTGTGTCCACTGCAGAACTGACGACCTGCGTGATTTGTGGGGAGAAAATCCCCACATACCTGGTGTCCGAAGCATGTTGCAAG ACTAGTGGGAGAAACTGAGTTTGTTTTTACTCTAAATTGTCAGACTGTTAGTCACTGCGGAGAGGTGCTTTCTGATGATTGAGTGGGGAT TCCTGTCCAATTGTGTGAGTTTGTGTCTCGGCCCTACCACTTTTTTTTTTTTTTTTTTTTGAAATGTAGTCTCGCCCTGTGGCCCAGGCT GGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCATCAGCCTCCCGAGTAGCTGGGAT TACAGGCGCCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAATAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGAATTCCT GACCTCAGGTGATCCACCTGCCTCAGCTTCCCAAAATGCTGGGATTACAGGTGTGAGCCATCGCACCGGGCCCTACCACTTATTGCTGTG GGCTTAACCTGTTTTCAGCCTGCTCTTTTAGGAATGGGGATGATAGTGATACCTGGTTAGGCTTTTTTGGGAGTTGGGTAAGTGCAGCAC TTGGTATGTGTTAAGCACCTCTGAGTGCTGTTACTGTCACCAGCGGCATCATCCAGGCAGAGCTGCGGACAAGGTGGCGGCGGGTGAGGG TGGTGTTTTGAGAATGGCTGAAATAAAAAAATACTGATTTATTTTATATAAAAATATGTTTTTATATATGATGTATAATATACGTATATC ATGGCATATGATACGTGTATATCATATAGCACATATAGTATACATATATATAGTCAGCAGAGATTTAGAGAAACTGGGCCTCGTGCATTG CAGGTGGGGACGGTAAGTGGTGCAGCTACTCTGGGAATCAGCCTGGCAGGTTTTTAGGAAGTTAAACCTGCCCTGCATTCCTGAGCTTTT ATTAGACAAATGAAAACTATTTTCACACAAAAACCCATATTTAATGTTCATAGCAACTTTATTTGTAATTACCAGAAACTGAAATAACTC AAATGGTTAAACTTGCACACTGATACCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCAT GATCCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCGTGAT CCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCC ACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACACTGCGTGATCCACT CTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCACTCTGCCACGTGGGTGGATCTCAAGGGCATTATGCTGAATAGGAAAAG CCAGTCTCAAAAGTTGTGTACTTGGCCGGTTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACAAG GTCAGGAGTTCAAGATCAGCCTGGCCAACATGGTGAGGCAGTCTCCACTAAAAATACAAAAAAATAGCGGGGCGTGGTGGCAGGTACCTG TAATCCCAGCTACTCGGGAGGCTGAGGCAGCAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCAGAGATCGTGCCACTGCACT CCAGCCTGGGCGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAATTGTTAATGGAACATTATAACCCAGTGTTCAGACCTAGCTGTTTC TCACATCTTTACCCATCGATCTGTCAAAGACCTTGTGATCATACTGATACTTCCAATTTCAATGCGACGTCCGCGGGTTTATTCTTTTTT TTTTAGGTGGAGTCTCACTCTGTTGTCCAGGCTGGAGACTCACTGCAACCTCTGCCTGCCCAGTTCAAGCGATTCTCCCACCTAGCCTGC TGAGTAGCTGGGATGACAGGTGCATGCCACCATGCCTGGCTAATTTTTGTGTTTTTAGTAGACACCTGGTTTCATCATGTTGGCCAGGCT GGTCTCAAACACCTGACCTCAAATGATCCATGCACCTTGGCCTCCCAAAGTGCTGGGATTACCAGCATGAGCCACCGTGTCCGGCTCCCT GGCTTTATTCTAATGCAAGAGTCAGTAAACTGTGGTCCAAACTGGCCCCCACCTATTTTCCTTAGTAAAGTTTTATTGGAATACAACCAT ACCCTTTTGTTTATGTATATCTGTGGCTGTTCTTTTTTTTTTTTTTTTTGGAGACGGGGTCTTGCTCTGTTGCCCAGGTTGGAGTGCAGT GGCACAAACAGGGCTCACTGCATCCTCAAACTCTTAGGCTTAATTTATCCTCCTTCCTCAGCCCCCCAAGTAGTTGGAACCACAGGTGCA CGTCACCACACTCAGCTAATTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGCCGCCATCTCTGCTCACT GCAAGTTCTGCCCCCTGGGTTCACACCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCATGGCCGGCTAA TTTTTTAGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTTGCCAGGATAGTCTCAATCTCCTGACCTCATGATCCACCTGCCTCGGCCT CCCAAAGTGCTGGGATTACAGGCATGAGTCACCGCGCCCAGCCATCAGATAATTTTTAAAGTTTTTGTAGAAAGGGTGTCGCTGTGTTAC CCAGGCTGGTCTTGAACTCCTGGGCTCAAGTGATCTTCCCGCCTCGGCCTCCCCAAGCGCTGGGGTGACAGGTGTGAGCCGCCACACGCG GCCTGTGGCTGTTCTGAGCACTCACGTGGCCTTTGGCTCATAGAGTCTGAGATGCTTACTCTCTCGCCCTTTACAGGAATCGTTTGCTGA AACCCTGTTCTCACTCCCACTTTCCTTTCTGTCATTGAGAGTCCTGGCTCTCATCAGCCACCGTGTATTCCAATTATTTGCTTTGCCCTA GAGTCCACAGAAAATAGCTTTAGGTGTGTTAACCTATACCATTGTGAAAACATCTACTGCCTAGAGCCTGTTCACACGGTAATGGTGCAC AGTCCTTTTTGTCTTTCTCCTTAGAGCACCTAGTCACTCACTGTTTTCCAAAGTTACGTAGGTTAGCTTCCCCTGTGTTACTCACTTGTA ATACAGTTAGGTGCATTTCTTCTGGCTAGTATTCCATGTGGGTGTCTCCCCCATCTTTTTGTTTATTTACTTATTTCTTTTTTTTTTGTT TTTTTTGTTGTTGTTGTTTTATTGAGGTGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGTAGTGGTGCGATCTCGGCTCACTGTGACCTC TGCCTCCTGGGTTCCAGCGAGTCTCCTGCCTCAGGTTCCCGAGTAGCTGGGATTACAGGTGCCCGCCACTGCGCCTGTCTAATTTTTGTA TTTTTTTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGGTCTCGAACTGCTGACCTCGTGATCCACCCACCTCGGTCTCCCAA AGTGCTGCGATTACAGGCGTGAGCCACCGCACCCGGCTTTACTTATTTGAGTATGTAAATCACGAACATGTTTTTAAAAGTCAGAACCCT GTAGAAACTTAAATTCAGATGTATTACTCCCCCCCGCCATCTTTTTTTTTGTTGTTGTTGTTGAGACAGGGTCTGATTCTGTCACCCAGG CTGGAGTGCAGGGTTGCCATCTCAGCTCGTGGTGGCATCCACCTCCCAGGCTCAAGTGATCCTCCTGCCTCAGCCCCCTGAGTAGCTGGG GCTGTAGGTGTGCACTACTATGCTCGGGTAATTTTTTTTTTTTGAAACAAGGTCTTGCTCTTGTCCCCTAGGCTGGAGTGCAGTGGCGTG ATTTCGGCTCACTGCAACCTCCACCTACTGGGTTCAAGCAATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGGTTACAGGCATGTACCAC CACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTG CCTGCCTCCCAAAGAATACAACGGGCTGGGCATGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGTTGGGAGTTCAAGACCAGCCT GACCAACATGGAGAAACCCCGTCTCTACTAAAAGTACAAAATTAGCTGGGCGTGGTGGTGCACGCCTGTAATCCCAGCTACTCGGGAGGC TTGAGGCAGGAGAACCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGCCTGGTGACAGAG CGAGACTCCGTCTCAAAAAGAAAAAAGGCTCACGCCTGTAATCCAAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCGGGAG TGCAAGACCAACCTGGCCAACATGGTGAAACCCCGTCTCTCCTAAAAATACAAAAATTAGCTAGGTGTGATTCCAGGCGCCTGTAGTCCC AGCTACTTGGGAGGCTGAGGCTGGAGAATCACTTGAACTCAGGAGGTAGAGGTTGCAGTGAGCTGCGATAGCACCACTGCACTCCAGCCT GTGCGACAGAGGGAGACACCATCTCGAAAAAAAAAAGAAAAATTCTTTTTTTTTTTTTGAGCTGGAGTTTCGCTCTTGTTGTCTAAGCTG GAGTGCAGGGGTGTGATCTCGGCTAATTGCAGCCTCCGCCTCCTGGGTTCAAGCGATTCTCCAGCCTCAGCCTCCCAAGTAGCTGGGATT ACAGGCATCCGCCACCACACCCGGCTAATTTTTTGTATTTTCAGTAGAGACGTGGTTTCACCATGTTGGCCGGGCTGGTCTCGAACTCCT GACCTCAGATGATCCGCCCGCCTCAGCCTCCCAAAATGCTGGGATTACAGGCGTGAGCCACCGCGTCCAGCCAAGAAAAAAAGTTTTTAA TGAAAGAAACAGAAACTGATGCCATTATATAATGAACCCTAGTACCCATCACCCAGCTTCAGCAGGTGTTAGTATTTTGTGACTCTTTGA TTTTTTTGTCTTGGGCCTAGGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAAT CGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGG AGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAA CCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAA GACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCC AGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGG GTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTC CTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAA CAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACAC CTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGT GATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTA CCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGA TGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCT TCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGAT CATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGT CTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAG GCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTA GTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTT GCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCA GGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCT TCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGT GATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTG TCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAG GGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGA GTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAG AGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCT >4500_4500_9_ANKLE2-NHP2L1_ANKLE2_chr12_133324417_ENST00000539605_NHP2L1_chr22_42076368_ENST00000401959_length(amino acids)=480AA_BP=353 MGLGEMTMDALLARLKLLNPDDLREEIVKAGLKCGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTD QAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPPSDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRF KAFSTREDAEKFARGICDYFPSPSKTSLPLSPVKTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSD LIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNP KAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRP -------------------------------------------------------------- >4500_4500_10_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000337516_NHP2L1_chr22_42076368_ENST00000215956_length(transcript)=2660nt_BP=1297nt GCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGC GGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCG GCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCAGGTGAAATGACAATGGATGCTCT GTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTAC AAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCAC AGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGG TTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGC TGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGT TTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAA ATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAA TGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGA CCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGG CTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCA GCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTA CGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCAC CAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGG CATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCC CTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGG CTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGC CAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAA ATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCAT CCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAG CTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCAT TGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATT TGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTG ATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGG CAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCA TGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGG GACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACAT >4500_4500_10_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000337516_NHP2L1_chr22_42076368_ENST00000215956_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_11_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000337516_NHP2L1_chr22_42076368_ENST00000355257_length(transcript)=2684nt_BP=1297nt GCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGC GGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCG GCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCAGGTGAAATGACAATGGATGCTCT GTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTAC AAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCAC AGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGG TTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGC TGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGT TTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAA ATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAA TGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGA CCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGG CTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCA GCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTA CGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCAC CAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGG CATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCC CTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGG CTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGC CAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAA ATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCAT CCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAG CTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCAT TGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATT TGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTG ATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGG CAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCA TGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGG GACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACAT >4500_4500_11_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000337516_NHP2L1_chr22_42076368_ENST00000355257_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_12_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000337516_NHP2L1_chr22_42076368_ENST00000401959_length(transcript)=2647nt_BP=1297nt GCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGC GGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCG GCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCAGGTGAAATGACAATGGATGCTCT GTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTAC AAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCAC AGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGG TTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGC TGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGT TTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAA ATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAA TGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGA CCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGG CTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCA GCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTA CGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCAC CAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGG CATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCC CTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGG CTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGC CAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAA ATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCAT CCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAG CTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCAT TGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATT TGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTG ATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGG CAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCA TGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGG GACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACAT >4500_4500_12_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000337516_NHP2L1_chr22_42076368_ENST00000401959_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_13_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000357997_NHP2L1_chr22_42076368_ENST00000215956_length(transcript)=2683nt_BP=1320nt AGGCAGGGCGCGGGCAGCCCGGCGCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCG ATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGG CTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCA GGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAA TGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTC TACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGT TTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCT AGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCA GCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTT TCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTG AAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGT TACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGG AGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAA GAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCC ATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTAT CCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAG GCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTG CTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCC TGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGT GGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCT ATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCC TCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAA AGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTG TGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTG CTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCC TGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGA GATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCA GAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGA AACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGG >4500_4500_13_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000357997_NHP2L1_chr22_42076368_ENST00000215956_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_14_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000357997_NHP2L1_chr22_42076368_ENST00000355257_length(transcript)=2707nt_BP=1320nt AGGCAGGGCGCGGGCAGCCCGGCGCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCG ATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGG CTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCA GGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAA TGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTC TACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGT TTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCT AGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCA GCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTT TCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTG AAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGT TACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGG AGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAA GAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCC ATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTAT CCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAG GCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTG CTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCC TGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGT GGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCT ATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCC TCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAA AGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTG TGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTG CTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCC TGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGA GATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCA GAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGA AACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGG GTCAGATGTACTCTCTGTCACATGAGGAGAGTGCTAGTTCATGTGTTCTCCATTCTTGTGAGCATCCTAATAAATCTGTTCCATTTTGAT >4500_4500_14_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000357997_NHP2L1_chr22_42076368_ENST00000355257_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_15_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000357997_NHP2L1_chr22_42076368_ENST00000401959_length(transcript)=2670nt_BP=1320nt AGGCAGGGCGCGGGCAGCCCGGCGCGGGGTCCTGGGACGGGCGCGGCGCGGGGCGCGGGCTTCTCGGCGGCTGCGGCCCGGGCGGCGGCG ATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTGATCGCTGTGCGGTGG CTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCCGCCGCCCCCGCCTCA GGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAATCGTCAAAGCCGGATTGAAA TGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGGAGGAAGGCTGTCTTCTTTC TACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAACCCAACTGATCAGGCTGGT TTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAAGACCTGCTCGGTGCCCCCT AGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCCAGTGTATGAGGACGTCCCA GCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGGGTCCCGATTTAAAGCTTTT TCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTCCTTACCACTGTCTCCTGTG AAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAACAAAGAGCGAGCGAACAGT TACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACACCTTTTCTGACCTTATCTGG AGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGTGATGCATGTTGCTGCCAAA GAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTACCCTGATGACGACGAGGCC ATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGATGTGAATCCAAAGGCCTAT CCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCTTCGGAAAGGAGCCAATGAG GCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGATCATTCTGCACCTGCCGCTG CTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGTCTCCAGGCCTGTCATCGCC TGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAGGCTCTTAGTCTAAACCTGT GGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTAGTATTTTCAGCTACTCTCT ATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTTGCTATCCCCCTTCCTTTCC TCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCAGGGTGGTGGCACCGTTGAA AGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCTTCCTGTTGTGTGCGGGGTG TGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGTGATCAAGGGGTTTCATTTG CTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTGTCGTTTACTAATGTACCCC TGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAGGGCAGCAGCATACCAAAGA GATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGAGTCGGGAGTGACAAGCTCA GAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAGAGATGGTGGAGTCCAAGGA AACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCTGTGTCCTGCCACCATGTGG >4500_4500_15_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000357997_NHP2L1_chr22_42076368_ENST00000401959_length(amino acids)=537AA_BP=410 MLWPRLAAAEWAALAWELLGASVLLIAVRWLVRRLGPRPGGLGRSGTPVPPPSAAAAPASGEMTMDALLARLKLLNPDDLREEIVKAGLK CGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTDQAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPP SDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRFKAFSTREDAEKFARGICDYFPSPSKTSLPLSPV KTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSDLIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAK ENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNPKAYPLADAHLTKKLLDLVQQSCNYKQLRKGANE -------------------------------------------------------------- >4500_4500_16_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000539605_NHP2L1_chr22_42076368_ENST00000215956_length(transcript)=9092nt_BP=7729nt GCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTG ATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCC GCCGCCCCCGCCTCAGGTAAGGCCCAGGCGGTCGCTGGGTCCCCGCACCCTGGCCCCTTCCCCGCCCCGACGCCCTCCTCGGGCCTGGGG TCCCGGCCGCGCCCCTGGAGCCGGCAGCAGTTGGGCGAGGCGGCCGGGGAAACCAGGGCCGGTCGGGAAAGGCCATTCCGGCCGCGGAAA GGGCAGTTGCGGGGACTTGGCTTCCCGGGCCGGGGGCGGAGGGGCCACGCCGGGTTCGGGGGTGAGAGCTTTCCCGGGCCCTGGAGCAGC CTCCGGGGAAGGCGGCGGGGGCCCGGCGAGGCGTTAGCGGAGACTCTTGCTGCGGTCTCTCGAGACCTGGGGAGGGATGGCCCAAAGGAG GGCGGCGCGGGGAGGAAACCCCTGGGTCCCGGATGTGTTTGGAACGTGAAGCCATTGCGGTTACTGGTCATGGAACATAAGGCAGAGACG GAAAAGGCAAATGTAACTCAGGGGTTTGGGGCCAGAGGAAGAGGGAGAAGGTGGCCATTTATTGCTTTGCGGTAGACTGTCGGGTCTGGG TGATGTGGAGATCAGAGGTGGGTTTTGGTCGTTTTAAGTTTGAGGTAACTGATACAGTGAACTGTGTATTTCAGCTCCATCCCCTTTTCC TGGCATACAACTCTTGAAATCCCGGGAACCTCCAAAGTGATGTCTTTTGTAGGCTGAGTGGACTGGTGGCCGGCAGCCCCTAGGGAGCTT CTGGATGGGGCTGGTCGCAGGAAAGACCAAGGCAGGGTTAGAGGTTCTGGGGACTTTCAGCCCCACCCCCAACCTCTGGGGAGGAGAGAG GGGTGAAGGTTGCGTTGATCACCAGTGGCTGATGAATCACGCCTGTGAAATGAAGTTCCTGTAAAAACCCAAAAGGGCTGGGTTCAGGGA GCTTCCAGATAGTACGTGGGGGTTCCTGGAGGCGGTGCCCAGAGAGGCCCTGAATTTCCAAGCGCTTCCCCCCGGTTTTACGTCACGCAT CTCTTCACCTGTATTCTTTGTAATCCTTTATACTCTGCTGGTAAGTGTAAGTAAAACATGTCTGTGAGTTCGGGAGCCACTCTAGCAAAT TACCGCAACCTGAGGAGGTCACCGGGTTACGCCCCGTCGGTCCCAAGCGCAGGTCAAACAACCTGGGCACTGGAAGTGGGGGGCAGTCTT GCGGGGCTGAGCCGTTAACCTGTGGGGGTCTGCTGGTATCTCCAGGAAGACGCTGTCAGAATAGATGACTGAATTAGGATGACAGACGAC ACCCAGCCTGTGTCCACTGCAGAACTGACGACCTGCGTGATTTGTGGGGAGAAAATCCCCACATACCTGGTGTCCGAAGCATGTTGCAAG ACTAGTGGGAGAAACTGAGTTTGTTTTTACTCTAAATTGTCAGACTGTTAGTCACTGCGGAGAGGTGCTTTCTGATGATTGAGTGGGGAT TCCTGTCCAATTGTGTGAGTTTGTGTCTCGGCCCTACCACTTTTTTTTTTTTTTTTTTTTGAAATGTAGTCTCGCCCTGTGGCCCAGGCT GGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCATCAGCCTCCCGAGTAGCTGGGAT TACAGGCGCCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAATAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGAATTCCT GACCTCAGGTGATCCACCTGCCTCAGCTTCCCAAAATGCTGGGATTACAGGTGTGAGCCATCGCACCGGGCCCTACCACTTATTGCTGTG GGCTTAACCTGTTTTCAGCCTGCTCTTTTAGGAATGGGGATGATAGTGATACCTGGTTAGGCTTTTTTGGGAGTTGGGTAAGTGCAGCAC TTGGTATGTGTTAAGCACCTCTGAGTGCTGTTACTGTCACCAGCGGCATCATCCAGGCAGAGCTGCGGACAAGGTGGCGGCGGGTGAGGG TGGTGTTTTGAGAATGGCTGAAATAAAAAAATACTGATTTATTTTATATAAAAATATGTTTTTATATATGATGTATAATATACGTATATC ATGGCATATGATACGTGTATATCATATAGCACATATAGTATACATATATATAGTCAGCAGAGATTTAGAGAAACTGGGCCTCGTGCATTG CAGGTGGGGACGGTAAGTGGTGCAGCTACTCTGGGAATCAGCCTGGCAGGTTTTTAGGAAGTTAAACCTGCCCTGCATTCCTGAGCTTTT ATTAGACAAATGAAAACTATTTTCACACAAAAACCCATATTTAATGTTCATAGCAACTTTATTTGTAATTACCAGAAACTGAAATAACTC AAATGGTTAAACTTGCACACTGATACCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCAT GATCCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCGTGAT CCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCC ACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACACTGCGTGATCCACT CTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCACTCTGCCACGTGGGTGGATCTCAAGGGCATTATGCTGAATAGGAAAAG CCAGTCTCAAAAGTTGTGTACTTGGCCGGTTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACAAG GTCAGGAGTTCAAGATCAGCCTGGCCAACATGGTGAGGCAGTCTCCACTAAAAATACAAAAAAATAGCGGGGCGTGGTGGCAGGTACCTG TAATCCCAGCTACTCGGGAGGCTGAGGCAGCAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCAGAGATCGTGCCACTGCACT CCAGCCTGGGCGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAATTGTTAATGGAACATTATAACCCAGTGTTCAGACCTAGCTGTTTC TCACATCTTTACCCATCGATCTGTCAAAGACCTTGTGATCATACTGATACTTCCAATTTCAATGCGACGTCCGCGGGTTTATTCTTTTTT TTTTAGGTGGAGTCTCACTCTGTTGTCCAGGCTGGAGACTCACTGCAACCTCTGCCTGCCCAGTTCAAGCGATTCTCCCACCTAGCCTGC TGAGTAGCTGGGATGACAGGTGCATGCCACCATGCCTGGCTAATTTTTGTGTTTTTAGTAGACACCTGGTTTCATCATGTTGGCCAGGCT GGTCTCAAACACCTGACCTCAAATGATCCATGCACCTTGGCCTCCCAAAGTGCTGGGATTACCAGCATGAGCCACCGTGTCCGGCTCCCT GGCTTTATTCTAATGCAAGAGTCAGTAAACTGTGGTCCAAACTGGCCCCCACCTATTTTCCTTAGTAAAGTTTTATTGGAATACAACCAT ACCCTTTTGTTTATGTATATCTGTGGCTGTTCTTTTTTTTTTTTTTTTTGGAGACGGGGTCTTGCTCTGTTGCCCAGGTTGGAGTGCAGT GGCACAAACAGGGCTCACTGCATCCTCAAACTCTTAGGCTTAATTTATCCTCCTTCCTCAGCCCCCCAAGTAGTTGGAACCACAGGTGCA CGTCACCACACTCAGCTAATTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGCCGCCATCTCTGCTCACT GCAAGTTCTGCCCCCTGGGTTCACACCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCATGGCCGGCTAA TTTTTTAGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTTGCCAGGATAGTCTCAATCTCCTGACCTCATGATCCACCTGCCTCGGCCT CCCAAAGTGCTGGGATTACAGGCATGAGTCACCGCGCCCAGCCATCAGATAATTTTTAAAGTTTTTGTAGAAAGGGTGTCGCTGTGTTAC CCAGGCTGGTCTTGAACTCCTGGGCTCAAGTGATCTTCCCGCCTCGGCCTCCCCAAGCGCTGGGGTGACAGGTGTGAGCCGCCACACGCG GCCTGTGGCTGTTCTGAGCACTCACGTGGCCTTTGGCTCATAGAGTCTGAGATGCTTACTCTCTCGCCCTTTACAGGAATCGTTTGCTGA AACCCTGTTCTCACTCCCACTTTCCTTTCTGTCATTGAGAGTCCTGGCTCTCATCAGCCACCGTGTATTCCAATTATTTGCTTTGCCCTA GAGTCCACAGAAAATAGCTTTAGGTGTGTTAACCTATACCATTGTGAAAACATCTACTGCCTAGAGCCTGTTCACACGGTAATGGTGCAC AGTCCTTTTTGTCTTTCTCCTTAGAGCACCTAGTCACTCACTGTTTTCCAAAGTTACGTAGGTTAGCTTCCCCTGTGTTACTCACTTGTA ATACAGTTAGGTGCATTTCTTCTGGCTAGTATTCCATGTGGGTGTCTCCCCCATCTTTTTGTTTATTTACTTATTTCTTTTTTTTTTGTT TTTTTTGTTGTTGTTGTTTTATTGAGGTGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGTAGTGGTGCGATCTCGGCTCACTGTGACCTC TGCCTCCTGGGTTCCAGCGAGTCTCCTGCCTCAGGTTCCCGAGTAGCTGGGATTACAGGTGCCCGCCACTGCGCCTGTCTAATTTTTGTA TTTTTTTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGGTCTCGAACTGCTGACCTCGTGATCCACCCACCTCGGTCTCCCAA AGTGCTGCGATTACAGGCGTGAGCCACCGCACCCGGCTTTACTTATTTGAGTATGTAAATCACGAACATGTTTTTAAAAGTCAGAACCCT GTAGAAACTTAAATTCAGATGTATTACTCCCCCCCGCCATCTTTTTTTTTGTTGTTGTTGTTGAGACAGGGTCTGATTCTGTCACCCAGG CTGGAGTGCAGGGTTGCCATCTCAGCTCGTGGTGGCATCCACCTCCCAGGCTCAAGTGATCCTCCTGCCTCAGCCCCCTGAGTAGCTGGG GCTGTAGGTGTGCACTACTATGCTCGGGTAATTTTTTTTTTTTGAAACAAGGTCTTGCTCTTGTCCCCTAGGCTGGAGTGCAGTGGCGTG ATTTCGGCTCACTGCAACCTCCACCTACTGGGTTCAAGCAATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGGTTACAGGCATGTACCAC CACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTG CCTGCCTCCCAAAGAATACAACGGGCTGGGCATGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGTTGGGAGTTCAAGACCAGCCT GACCAACATGGAGAAACCCCGTCTCTACTAAAAGTACAAAATTAGCTGGGCGTGGTGGTGCACGCCTGTAATCCCAGCTACTCGGGAGGC TTGAGGCAGGAGAACCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGCCTGGTGACAGAG CGAGACTCCGTCTCAAAAAGAAAAAAGGCTCACGCCTGTAATCCAAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCGGGAG TGCAAGACCAACCTGGCCAACATGGTGAAACCCCGTCTCTCCTAAAAATACAAAAATTAGCTAGGTGTGATTCCAGGCGCCTGTAGTCCC AGCTACTTGGGAGGCTGAGGCTGGAGAATCACTTGAACTCAGGAGGTAGAGGTTGCAGTGAGCTGCGATAGCACCACTGCACTCCAGCCT GTGCGACAGAGGGAGACACCATCTCGAAAAAAAAAAGAAAAATTCTTTTTTTTTTTTTGAGCTGGAGTTTCGCTCTTGTTGTCTAAGCTG GAGTGCAGGGGTGTGATCTCGGCTAATTGCAGCCTCCGCCTCCTGGGTTCAAGCGATTCTCCAGCCTCAGCCTCCCAAGTAGCTGGGATT ACAGGCATCCGCCACCACACCCGGCTAATTTTTTGTATTTTCAGTAGAGACGTGGTTTCACCATGTTGGCCGGGCTGGTCTCGAACTCCT GACCTCAGATGATCCGCCCGCCTCAGCCTCCCAAAATGCTGGGATTACAGGCGTGAGCCACCGCGTCCAGCCAAGAAAAAAAGTTTTTAA TGAAAGAAACAGAAACTGATGCCATTATATAATGAACCCTAGTACCCATCACCCAGCTTCAGCAGGTGTTAGTATTTTGTGACTCTTTGA TTTTTTTGTCTTGGGCCTAGGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAAT CGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGG AGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAA CCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAA GACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCC AGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGG GTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTC CTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAA CAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACAC CTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGT GATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTA CCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGA TGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCT TCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGAT CATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGT CTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAG GCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTA GTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTT GCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCA GGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCT TCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGT GATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTG TCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAG GGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGA GTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAG AGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCT GTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACATGAGGAGAGTGCTAGTTCATGTGTTCTCCATTCTTGTGAGCATCCTAAT >4500_4500_16_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000539605_NHP2L1_chr22_42076368_ENST00000215956_length(amino acids)=480AA_BP=353 MGLGEMTMDALLARLKLLNPDDLREEIVKAGLKCGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTD QAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPPSDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRF KAFSTREDAEKFARGICDYFPSPSKTSLPLSPVKTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSD LIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNP KAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRP -------------------------------------------------------------- >4500_4500_17_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000539605_NHP2L1_chr22_42076368_ENST00000355257_length(transcript)=9116nt_BP=7729nt GCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTG ATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCC GCCGCCCCCGCCTCAGGTAAGGCCCAGGCGGTCGCTGGGTCCCCGCACCCTGGCCCCTTCCCCGCCCCGACGCCCTCCTCGGGCCTGGGG TCCCGGCCGCGCCCCTGGAGCCGGCAGCAGTTGGGCGAGGCGGCCGGGGAAACCAGGGCCGGTCGGGAAAGGCCATTCCGGCCGCGGAAA GGGCAGTTGCGGGGACTTGGCTTCCCGGGCCGGGGGCGGAGGGGCCACGCCGGGTTCGGGGGTGAGAGCTTTCCCGGGCCCTGGAGCAGC CTCCGGGGAAGGCGGCGGGGGCCCGGCGAGGCGTTAGCGGAGACTCTTGCTGCGGTCTCTCGAGACCTGGGGAGGGATGGCCCAAAGGAG GGCGGCGCGGGGAGGAAACCCCTGGGTCCCGGATGTGTTTGGAACGTGAAGCCATTGCGGTTACTGGTCATGGAACATAAGGCAGAGACG GAAAAGGCAAATGTAACTCAGGGGTTTGGGGCCAGAGGAAGAGGGAGAAGGTGGCCATTTATTGCTTTGCGGTAGACTGTCGGGTCTGGG TGATGTGGAGATCAGAGGTGGGTTTTGGTCGTTTTAAGTTTGAGGTAACTGATACAGTGAACTGTGTATTTCAGCTCCATCCCCTTTTCC TGGCATACAACTCTTGAAATCCCGGGAACCTCCAAAGTGATGTCTTTTGTAGGCTGAGTGGACTGGTGGCCGGCAGCCCCTAGGGAGCTT CTGGATGGGGCTGGTCGCAGGAAAGACCAAGGCAGGGTTAGAGGTTCTGGGGACTTTCAGCCCCACCCCCAACCTCTGGGGAGGAGAGAG GGGTGAAGGTTGCGTTGATCACCAGTGGCTGATGAATCACGCCTGTGAAATGAAGTTCCTGTAAAAACCCAAAAGGGCTGGGTTCAGGGA GCTTCCAGATAGTACGTGGGGGTTCCTGGAGGCGGTGCCCAGAGAGGCCCTGAATTTCCAAGCGCTTCCCCCCGGTTTTACGTCACGCAT CTCTTCACCTGTATTCTTTGTAATCCTTTATACTCTGCTGGTAAGTGTAAGTAAAACATGTCTGTGAGTTCGGGAGCCACTCTAGCAAAT TACCGCAACCTGAGGAGGTCACCGGGTTACGCCCCGTCGGTCCCAAGCGCAGGTCAAACAACCTGGGCACTGGAAGTGGGGGGCAGTCTT GCGGGGCTGAGCCGTTAACCTGTGGGGGTCTGCTGGTATCTCCAGGAAGACGCTGTCAGAATAGATGACTGAATTAGGATGACAGACGAC ACCCAGCCTGTGTCCACTGCAGAACTGACGACCTGCGTGATTTGTGGGGAGAAAATCCCCACATACCTGGTGTCCGAAGCATGTTGCAAG ACTAGTGGGAGAAACTGAGTTTGTTTTTACTCTAAATTGTCAGACTGTTAGTCACTGCGGAGAGGTGCTTTCTGATGATTGAGTGGGGAT TCCTGTCCAATTGTGTGAGTTTGTGTCTCGGCCCTACCACTTTTTTTTTTTTTTTTTTTTGAAATGTAGTCTCGCCCTGTGGCCCAGGCT GGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCATCAGCCTCCCGAGTAGCTGGGAT TACAGGCGCCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAATAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGAATTCCT GACCTCAGGTGATCCACCTGCCTCAGCTTCCCAAAATGCTGGGATTACAGGTGTGAGCCATCGCACCGGGCCCTACCACTTATTGCTGTG GGCTTAACCTGTTTTCAGCCTGCTCTTTTAGGAATGGGGATGATAGTGATACCTGGTTAGGCTTTTTTGGGAGTTGGGTAAGTGCAGCAC TTGGTATGTGTTAAGCACCTCTGAGTGCTGTTACTGTCACCAGCGGCATCATCCAGGCAGAGCTGCGGACAAGGTGGCGGCGGGTGAGGG TGGTGTTTTGAGAATGGCTGAAATAAAAAAATACTGATTTATTTTATATAAAAATATGTTTTTATATATGATGTATAATATACGTATATC ATGGCATATGATACGTGTATATCATATAGCACATATAGTATACATATATATAGTCAGCAGAGATTTAGAGAAACTGGGCCTCGTGCATTG CAGGTGGGGACGGTAAGTGGTGCAGCTACTCTGGGAATCAGCCTGGCAGGTTTTTAGGAAGTTAAACCTGCCCTGCATTCCTGAGCTTTT ATTAGACAAATGAAAACTATTTTCACACAAAAACCCATATTTAATGTTCATAGCAACTTTATTTGTAATTACCAGAAACTGAAATAACTC AAATGGTTAAACTTGCACACTGATACCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCAT GATCCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCGTGAT CCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCC ACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACACTGCGTGATCCACT CTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCACTCTGCCACGTGGGTGGATCTCAAGGGCATTATGCTGAATAGGAAAAG CCAGTCTCAAAAGTTGTGTACTTGGCCGGTTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACAAG GTCAGGAGTTCAAGATCAGCCTGGCCAACATGGTGAGGCAGTCTCCACTAAAAATACAAAAAAATAGCGGGGCGTGGTGGCAGGTACCTG TAATCCCAGCTACTCGGGAGGCTGAGGCAGCAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCAGAGATCGTGCCACTGCACT CCAGCCTGGGCGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAATTGTTAATGGAACATTATAACCCAGTGTTCAGACCTAGCTGTTTC TCACATCTTTACCCATCGATCTGTCAAAGACCTTGTGATCATACTGATACTTCCAATTTCAATGCGACGTCCGCGGGTTTATTCTTTTTT TTTTAGGTGGAGTCTCACTCTGTTGTCCAGGCTGGAGACTCACTGCAACCTCTGCCTGCCCAGTTCAAGCGATTCTCCCACCTAGCCTGC TGAGTAGCTGGGATGACAGGTGCATGCCACCATGCCTGGCTAATTTTTGTGTTTTTAGTAGACACCTGGTTTCATCATGTTGGCCAGGCT GGTCTCAAACACCTGACCTCAAATGATCCATGCACCTTGGCCTCCCAAAGTGCTGGGATTACCAGCATGAGCCACCGTGTCCGGCTCCCT GGCTTTATTCTAATGCAAGAGTCAGTAAACTGTGGTCCAAACTGGCCCCCACCTATTTTCCTTAGTAAAGTTTTATTGGAATACAACCAT ACCCTTTTGTTTATGTATATCTGTGGCTGTTCTTTTTTTTTTTTTTTTTGGAGACGGGGTCTTGCTCTGTTGCCCAGGTTGGAGTGCAGT GGCACAAACAGGGCTCACTGCATCCTCAAACTCTTAGGCTTAATTTATCCTCCTTCCTCAGCCCCCCAAGTAGTTGGAACCACAGGTGCA CGTCACCACACTCAGCTAATTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGCCGCCATCTCTGCTCACT GCAAGTTCTGCCCCCTGGGTTCACACCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCATGGCCGGCTAA TTTTTTAGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTTGCCAGGATAGTCTCAATCTCCTGACCTCATGATCCACCTGCCTCGGCCT CCCAAAGTGCTGGGATTACAGGCATGAGTCACCGCGCCCAGCCATCAGATAATTTTTAAAGTTTTTGTAGAAAGGGTGTCGCTGTGTTAC CCAGGCTGGTCTTGAACTCCTGGGCTCAAGTGATCTTCCCGCCTCGGCCTCCCCAAGCGCTGGGGTGACAGGTGTGAGCCGCCACACGCG GCCTGTGGCTGTTCTGAGCACTCACGTGGCCTTTGGCTCATAGAGTCTGAGATGCTTACTCTCTCGCCCTTTACAGGAATCGTTTGCTGA AACCCTGTTCTCACTCCCACTTTCCTTTCTGTCATTGAGAGTCCTGGCTCTCATCAGCCACCGTGTATTCCAATTATTTGCTTTGCCCTA GAGTCCACAGAAAATAGCTTTAGGTGTGTTAACCTATACCATTGTGAAAACATCTACTGCCTAGAGCCTGTTCACACGGTAATGGTGCAC AGTCCTTTTTGTCTTTCTCCTTAGAGCACCTAGTCACTCACTGTTTTCCAAAGTTACGTAGGTTAGCTTCCCCTGTGTTACTCACTTGTA ATACAGTTAGGTGCATTTCTTCTGGCTAGTATTCCATGTGGGTGTCTCCCCCATCTTTTTGTTTATTTACTTATTTCTTTTTTTTTTGTT TTTTTTGTTGTTGTTGTTTTATTGAGGTGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGTAGTGGTGCGATCTCGGCTCACTGTGACCTC TGCCTCCTGGGTTCCAGCGAGTCTCCTGCCTCAGGTTCCCGAGTAGCTGGGATTACAGGTGCCCGCCACTGCGCCTGTCTAATTTTTGTA TTTTTTTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGGTCTCGAACTGCTGACCTCGTGATCCACCCACCTCGGTCTCCCAA AGTGCTGCGATTACAGGCGTGAGCCACCGCACCCGGCTTTACTTATTTGAGTATGTAAATCACGAACATGTTTTTAAAAGTCAGAACCCT GTAGAAACTTAAATTCAGATGTATTACTCCCCCCCGCCATCTTTTTTTTTGTTGTTGTTGTTGAGACAGGGTCTGATTCTGTCACCCAGG CTGGAGTGCAGGGTTGCCATCTCAGCTCGTGGTGGCATCCACCTCCCAGGCTCAAGTGATCCTCCTGCCTCAGCCCCCTGAGTAGCTGGG GCTGTAGGTGTGCACTACTATGCTCGGGTAATTTTTTTTTTTTGAAACAAGGTCTTGCTCTTGTCCCCTAGGCTGGAGTGCAGTGGCGTG ATTTCGGCTCACTGCAACCTCCACCTACTGGGTTCAAGCAATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGGTTACAGGCATGTACCAC CACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTG CCTGCCTCCCAAAGAATACAACGGGCTGGGCATGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGTTGGGAGTTCAAGACCAGCCT GACCAACATGGAGAAACCCCGTCTCTACTAAAAGTACAAAATTAGCTGGGCGTGGTGGTGCACGCCTGTAATCCCAGCTACTCGGGAGGC TTGAGGCAGGAGAACCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGCCTGGTGACAGAG CGAGACTCCGTCTCAAAAAGAAAAAAGGCTCACGCCTGTAATCCAAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCGGGAG TGCAAGACCAACCTGGCCAACATGGTGAAACCCCGTCTCTCCTAAAAATACAAAAATTAGCTAGGTGTGATTCCAGGCGCCTGTAGTCCC AGCTACTTGGGAGGCTGAGGCTGGAGAATCACTTGAACTCAGGAGGTAGAGGTTGCAGTGAGCTGCGATAGCACCACTGCACTCCAGCCT GTGCGACAGAGGGAGACACCATCTCGAAAAAAAAAAGAAAAATTCTTTTTTTTTTTTTGAGCTGGAGTTTCGCTCTTGTTGTCTAAGCTG GAGTGCAGGGGTGTGATCTCGGCTAATTGCAGCCTCCGCCTCCTGGGTTCAAGCGATTCTCCAGCCTCAGCCTCCCAAGTAGCTGGGATT ACAGGCATCCGCCACCACACCCGGCTAATTTTTTGTATTTTCAGTAGAGACGTGGTTTCACCATGTTGGCCGGGCTGGTCTCGAACTCCT GACCTCAGATGATCCGCCCGCCTCAGCCTCCCAAAATGCTGGGATTACAGGCGTGAGCCACCGCGTCCAGCCAAGAAAAAAAGTTTTTAA TGAAAGAAACAGAAACTGATGCCATTATATAATGAACCCTAGTACCCATCACCCAGCTTCAGCAGGTGTTAGTATTTTGTGACTCTTTGA TTTTTTTGTCTTGGGCCTAGGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAAT CGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGG AGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAA CCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAA GACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCC AGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGG GTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTC CTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAA CAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACAC CTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGT GATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTA CCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGA TGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCT TCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGAT CATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGT CTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAG GCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTA GTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTT GCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCA GGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCT TCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGT GATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTG TCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAG GGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGA GTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAG AGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCT GTGTCCTGCCACCATGTGGGTCAGATGTACTCTCTGTCACATGAGGAGAGTGCTAGTTCATGTGTTCTCCATTCTTGTGAGCATCCTAAT >4500_4500_17_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000539605_NHP2L1_chr22_42076368_ENST00000355257_length(amino acids)=480AA_BP=353 MGLGEMTMDALLARLKLLNPDDLREEIVKAGLKCGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTD QAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPPSDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRF KAFSTREDAEKFARGICDYFPSPSKTSLPLSPVKTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSD LIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNP KAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRP -------------------------------------------------------------- >4500_4500_18_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000539605_NHP2L1_chr22_42076368_ENST00000401959_length(transcript)=9079nt_BP=7729nt GCCCGGGCGGCGGCGATGCTGTGGCCGCGGCTGGCGGCGGCCGAGTGGGCGGCGCTGGCCTGGGAGCTGCTGGGCGCCTCGGTGCTGCTG ATCGCTGTGCGGTGGCTGGTGCGGCGGCTGGGCCCGCGGCCGGGAGGTCTGGGCCGCAGCGGGACCCCAGTTCCTCCGCCAAGCGCGGCC GCCGCCCCCGCCTCAGGTAAGGCCCAGGCGGTCGCTGGGTCCCCGCACCCTGGCCCCTTCCCCGCCCCGACGCCCTCCTCGGGCCTGGGG TCCCGGCCGCGCCCCTGGAGCCGGCAGCAGTTGGGCGAGGCGGCCGGGGAAACCAGGGCCGGTCGGGAAAGGCCATTCCGGCCGCGGAAA GGGCAGTTGCGGGGACTTGGCTTCCCGGGCCGGGGGCGGAGGGGCCACGCCGGGTTCGGGGGTGAGAGCTTTCCCGGGCCCTGGAGCAGC CTCCGGGGAAGGCGGCGGGGGCCCGGCGAGGCGTTAGCGGAGACTCTTGCTGCGGTCTCTCGAGACCTGGGGAGGGATGGCCCAAAGGAG GGCGGCGCGGGGAGGAAACCCCTGGGTCCCGGATGTGTTTGGAACGTGAAGCCATTGCGGTTACTGGTCATGGAACATAAGGCAGAGACG GAAAAGGCAAATGTAACTCAGGGGTTTGGGGCCAGAGGAAGAGGGAGAAGGTGGCCATTTATTGCTTTGCGGTAGACTGTCGGGTCTGGG TGATGTGGAGATCAGAGGTGGGTTTTGGTCGTTTTAAGTTTGAGGTAACTGATACAGTGAACTGTGTATTTCAGCTCCATCCCCTTTTCC TGGCATACAACTCTTGAAATCCCGGGAACCTCCAAAGTGATGTCTTTTGTAGGCTGAGTGGACTGGTGGCCGGCAGCCCCTAGGGAGCTT CTGGATGGGGCTGGTCGCAGGAAAGACCAAGGCAGGGTTAGAGGTTCTGGGGACTTTCAGCCCCACCCCCAACCTCTGGGGAGGAGAGAG GGGTGAAGGTTGCGTTGATCACCAGTGGCTGATGAATCACGCCTGTGAAATGAAGTTCCTGTAAAAACCCAAAAGGGCTGGGTTCAGGGA GCTTCCAGATAGTACGTGGGGGTTCCTGGAGGCGGTGCCCAGAGAGGCCCTGAATTTCCAAGCGCTTCCCCCCGGTTTTACGTCACGCAT CTCTTCACCTGTATTCTTTGTAATCCTTTATACTCTGCTGGTAAGTGTAAGTAAAACATGTCTGTGAGTTCGGGAGCCACTCTAGCAAAT TACCGCAACCTGAGGAGGTCACCGGGTTACGCCCCGTCGGTCCCAAGCGCAGGTCAAACAACCTGGGCACTGGAAGTGGGGGGCAGTCTT GCGGGGCTGAGCCGTTAACCTGTGGGGGTCTGCTGGTATCTCCAGGAAGACGCTGTCAGAATAGATGACTGAATTAGGATGACAGACGAC ACCCAGCCTGTGTCCACTGCAGAACTGACGACCTGCGTGATTTGTGGGGAGAAAATCCCCACATACCTGGTGTCCGAAGCATGTTGCAAG ACTAGTGGGAGAAACTGAGTTTGTTTTTACTCTAAATTGTCAGACTGTTAGTCACTGCGGAGAGGTGCTTTCTGATGATTGAGTGGGGAT TCCTGTCCAATTGTGTGAGTTTGTGTCTCGGCCCTACCACTTTTTTTTTTTTTTTTTTTTGAAATGTAGTCTCGCCCTGTGGCCCAGGCT GGAGTGCAGTGGCGCGATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCAAGCGATTCTCCTGCATCAGCCTCCCGAGTAGCTGGGAT TACAGGCGCCTGCCACCACGCCCGGCTAATTTTTGTATTTTTAATAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGAATTCCT GACCTCAGGTGATCCACCTGCCTCAGCTTCCCAAAATGCTGGGATTACAGGTGTGAGCCATCGCACCGGGCCCTACCACTTATTGCTGTG GGCTTAACCTGTTTTCAGCCTGCTCTTTTAGGAATGGGGATGATAGTGATACCTGGTTAGGCTTTTTTGGGAGTTGGGTAAGTGCAGCAC TTGGTATGTGTTAAGCACCTCTGAGTGCTGTTACTGTCACCAGCGGCATCATCCAGGCAGAGCTGCGGACAAGGTGGCGGCGGGTGAGGG TGGTGTTTTGAGAATGGCTGAAATAAAAAAATACTGATTTATTTTATATAAAAATATGTTTTTATATATGATGTATAATATACGTATATC ATGGCATATGATACGTGTATATCATATAGCACATATAGTATACATATATATAGTCAGCAGAGATTTAGAGAAACTGGGCCTCGTGCATTG CAGGTGGGGACGGTAAGTGGTGCAGCTACTCTGGGAATCAGCCTGGCAGGTTTTTAGGAAGTTAAACCTGCCCTGCATTCCTGAGCTTTT ATTAGACAAATGAAAACTATTTTCACACAAAAACCCATATTTAATGTTCATAGCAACTTTATTTGTAATTACCAGAAACTGAAATAACTC AAATGGTTAAACTTGCACACTGATACCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCAT GATCCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCTGCGTGAT CCACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCC ACTCTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCTCTCTGCCACGTGGGTGCCCCGGGGTGCCACACTGCGTGATCCACT CTGCCACGTGGGTGCCCCGGGGTGCCACTCCGCAGCGATCCACTCTGCCACGTGGGTGGATCTCAAGGGCATTATGCTGAATAGGAAAAG CCAGTCTCAAAAGTTGTGTACTTGGCCGGTTGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACAAG GTCAGGAGTTCAAGATCAGCCTGGCCAACATGGTGAGGCAGTCTCCACTAAAAATACAAAAAAATAGCGGGGCGTGGTGGCAGGTACCTG TAATCCCAGCTACTCGGGAGGCTGAGGCAGCAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCGGTGAGCAGAGATCGTGCCACTGCACT CCAGCCTGGGCGACAGAGCAAGACTCCATCTCAAAAAAAAAAAAATTGTTAATGGAACATTATAACCCAGTGTTCAGACCTAGCTGTTTC TCACATCTTTACCCATCGATCTGTCAAAGACCTTGTGATCATACTGATACTTCCAATTTCAATGCGACGTCCGCGGGTTTATTCTTTTTT TTTTAGGTGGAGTCTCACTCTGTTGTCCAGGCTGGAGACTCACTGCAACCTCTGCCTGCCCAGTTCAAGCGATTCTCCCACCTAGCCTGC TGAGTAGCTGGGATGACAGGTGCATGCCACCATGCCTGGCTAATTTTTGTGTTTTTAGTAGACACCTGGTTTCATCATGTTGGCCAGGCT GGTCTCAAACACCTGACCTCAAATGATCCATGCACCTTGGCCTCCCAAAGTGCTGGGATTACCAGCATGAGCCACCGTGTCCGGCTCCCT GGCTTTATTCTAATGCAAGAGTCAGTAAACTGTGGTCCAAACTGGCCCCCACCTATTTTCCTTAGTAAAGTTTTATTGGAATACAACCAT ACCCTTTTGTTTATGTATATCTGTGGCTGTTCTTTTTTTTTTTTTTTTTGGAGACGGGGTCTTGCTCTGTTGCCCAGGTTGGAGTGCAGT GGCACAAACAGGGCTCACTGCATCCTCAAACTCTTAGGCTTAATTTATCCTCCTTCCTCAGCCCCCCAAGTAGTTGGAACCACAGGTGCA CGTCACCACACTCAGCTAATTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCTGGAGTGCAGTGCCGCCATCTCTGCTCACT GCAAGTTCTGCCCCCTGGGTTCACACCATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGCCCGCCACCATGGCCGGCTAA TTTTTTAGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTTGCCAGGATAGTCTCAATCTCCTGACCTCATGATCCACCTGCCTCGGCCT CCCAAAGTGCTGGGATTACAGGCATGAGTCACCGCGCCCAGCCATCAGATAATTTTTAAAGTTTTTGTAGAAAGGGTGTCGCTGTGTTAC CCAGGCTGGTCTTGAACTCCTGGGCTCAAGTGATCTTCCCGCCTCGGCCTCCCCAAGCGCTGGGGTGACAGGTGTGAGCCGCCACACGCG GCCTGTGGCTGTTCTGAGCACTCACGTGGCCTTTGGCTCATAGAGTCTGAGATGCTTACTCTCTCGCCCTTTACAGGAATCGTTTGCTGA AACCCTGTTCTCACTCCCACTTTCCTTTCTGTCATTGAGAGTCCTGGCTCTCATCAGCCACCGTGTATTCCAATTATTTGCTTTGCCCTA GAGTCCACAGAAAATAGCTTTAGGTGTGTTAACCTATACCATTGTGAAAACATCTACTGCCTAGAGCCTGTTCACACGGTAATGGTGCAC AGTCCTTTTTGTCTTTCTCCTTAGAGCACCTAGTCACTCACTGTTTTCCAAAGTTACGTAGGTTAGCTTCCCCTGTGTTACTCACTTGTA ATACAGTTAGGTGCATTTCTTCTGGCTAGTATTCCATGTGGGTGTCTCCCCCATCTTTTTGTTTATTTACTTATTTCTTTTTTTTTTGTT TTTTTTGTTGTTGTTGTTTTATTGAGGTGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGTAGTGGTGCGATCTCGGCTCACTGTGACCTC TGCCTCCTGGGTTCCAGCGAGTCTCCTGCCTCAGGTTCCCGAGTAGCTGGGATTACAGGTGCCCGCCACTGCGCCTGTCTAATTTTTGTA TTTTTTTTTTAGTAGAGATGGGGTTTCACCATCTTGGCCAGGCTGGTCTCGAACTGCTGACCTCGTGATCCACCCACCTCGGTCTCCCAA AGTGCTGCGATTACAGGCGTGAGCCACCGCACCCGGCTTTACTTATTTGAGTATGTAAATCACGAACATGTTTTTAAAAGTCAGAACCCT GTAGAAACTTAAATTCAGATGTATTACTCCCCCCCGCCATCTTTTTTTTTGTTGTTGTTGTTGAGACAGGGTCTGATTCTGTCACCCAGG CTGGAGTGCAGGGTTGCCATCTCAGCTCGTGGTGGCATCCACCTCCCAGGCTCAAGTGATCCTCCTGCCTCAGCCCCCTGAGTAGCTGGG GCTGTAGGTGTGCACTACTATGCTCGGGTAATTTTTTTTTTTTGAAACAAGGTCTTGCTCTTGTCCCCTAGGCTGGAGTGCAGTGGCGTG ATTTCGGCTCACTGCAACCTCCACCTACTGGGTTCAAGCAATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGGTTACAGGCATGTACCAC CACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTG CCTGCCTCCCAAAGAATACAACGGGCTGGGCATGGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGTTGGGAGTTCAAGACCAGCCT GACCAACATGGAGAAACCCCGTCTCTACTAAAAGTACAAAATTAGCTGGGCGTGGTGGTGCACGCCTGTAATCCCAGCTACTCGGGAGGC TTGAGGCAGGAGAACCGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCCTGCCTGGTGACAGAG CGAGACTCCGTCTCAAAAAGAAAAAAGGCTCACGCCTGTAATCCAAACACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGTCGGGAG TGCAAGACCAACCTGGCCAACATGGTGAAACCCCGTCTCTCCTAAAAATACAAAAATTAGCTAGGTGTGATTCCAGGCGCCTGTAGTCCC AGCTACTTGGGAGGCTGAGGCTGGAGAATCACTTGAACTCAGGAGGTAGAGGTTGCAGTGAGCTGCGATAGCACCACTGCACTCCAGCCT GTGCGACAGAGGGAGACACCATCTCGAAAAAAAAAAGAAAAATTCTTTTTTTTTTTTTGAGCTGGAGTTTCGCTCTTGTTGTCTAAGCTG GAGTGCAGGGGTGTGATCTCGGCTAATTGCAGCCTCCGCCTCCTGGGTTCAAGCGATTCTCCAGCCTCAGCCTCCCAAGTAGCTGGGATT ACAGGCATCCGCCACCACACCCGGCTAATTTTTTGTATTTTCAGTAGAGACGTGGTTTCACCATGTTGGCCGGGCTGGTCTCGAACTCCT GACCTCAGATGATCCGCCCGCCTCAGCCTCCCAAAATGCTGGGATTACAGGCGTGAGCCACCGCGTCCAGCCAAGAAAAAAAGTTTTTAA TGAAAGAAACAGAAACTGATGCCATTATATAATGAACCCTAGTACCCATCACCCAGCTTCAGCAGGTGTTAGTATTTTGTGACTCTTTGA TTTTTTTGTCTTGGGCCTAGGTGAAATGACAATGGATGCTCTGTTGGCTCGATTGAAACTTCTGAATCCAGATGACCTTAGAGAAGAAAT CGTCAAAGCCGGATTGAAATGTGGACCCATTACATCAACTACAAGGTTCATTTTTGAGAAAAAATTGGCTCAGGCTTTACTGGAGCAAGG AGGAAGGCTGTCTTCTTTCTACCACCATGAGGCAGGTGTCACAGCTCTCAGCCAGGACCCACAAAGGATTTTGAAGCCAGCTGAAGGGAA CCCAACTGATCAGGCTGGTTTTTCTGAAGACAGAGATTTTGGTTACAGTGTGGGCCTGAATCCTCCAGAGGAGGAAGCTGTGACATCCAA GACCTGCTCGGTGCCCCCTAGTGACACCGACACCTACAGAGCTGGAGCGACTGCGTCTAAGGAGCCGCCCCTGTACTATGGGGTGTGTCC AGTGTATGAGGACGTCCCAGCGAGAAATGAAAGGATCTATGTTTATGAAAATAAAAAGGAAGCATTGCAAGCTGTCAAGATGATCAAAGG GTCCCGATTTAAAGCTTTTTCTACCAGAGAAGACGCTGAGAAATTTGCTAGAGGAATTTGTGATTATTTCCCTTCTCCAAGCAAAACGTC CTTACCACTGTCTCCTGTGAAAACAGCTCCACTCTTTAGCAATGACAGGTTGAAAGATGGTTTGTGCTTGTCGGAATCAGAAACAGTCAA CAAAGAGCGAGCGAACAGTTACAAAAATCCCCGCACGCAGGACCTCACCGCCAAGCTTCGGAAAGCTGTGGAGAAGGGAGAGGAGGACAC CTTTTCTGACCTTATCTGGAGCAACCCCCGGTATCTGATAGGCTCAGGAGACAACCCCACTATCGTGCAGGAAGGGTGCAGGTACAACGT GATGCATGTTGCTGCCAAAGAGAACCAGGCTTCCATCTGCCAGCTGACTCTGGACGTCCTGGAGAACCCTGACTTCATGAGGCTGATGTA CCCTGATGACGACGAGGCCATGCTGCAGAAGCGTATCCGTTACGTGGTGGACCTGTACCTCAACACCCCCGACAAGATGACTGAGGCTGA TGTGAATCCAAAGGCCTATCCCCTTGCCGATGCCCACCTCACCAAGAAGCTACTGGACCTCGTTCAGCAGTCATGTAACTATAAGCAGCT TCGGAAAGGAGCCAATGAGGCCACCAAAACCCTCAACAGGGGCATCTCTGAGTTCATCGTGATGGCTGCAGACGCCGAGCCACTGGAGAT CATTCTGCACCTGCCGCTGCTGTGTGAAGACAAGAATGTGCCCTACGTGTTTGTGCGCTCCAAGCAGGCCCTGGGGAGAGCCTGTGGGGT CTCCAGGCCTGTCATCGCCTGTTCTGTCACCATCAAAGAAGGCTCGCAGCTGAAACAGCAGATCCAATCCATTCAGCAGTCCATTGAAAG GCTCTTAGTCTAAACCTGTGGCCTCTGCCACGTGCTCCCTGCCAGCTTCCCCCCTGAGGTTGTGTATCATATTATCTGTGTTAGCATGTA GTATTTTCAGCTACTCTCTATTGTTATAAAATGTAGTACTAAATCTGGTTTCTGGATTTTTGTGTTGTTTTTGTTCTGTTTTACAGGGTT GCTATCCCCCTTCCTTTCCTCCCTCCCTCTGCCATCCTTCATCCTTTTATCCTCCCTTTTTGGAACAAGTGTTCAGAGCAGACAGAAGCA GGGTGGTGGCACCGTTGAAAGGCAGAAAGAGCCAGGAGAAAGCTGATGGAGCCAGGACAGAGATCTGGTTCCAGCTTTCAGCCACTAGCT TCCTGTTGTGTGCGGGGTGTGGTGGAATTAAACAGCATTCATTGTGTGTCCCTGTGCCTGGCACACAGAATCATTCATACGTGTTCAAGT GATCAAGGGGTTTCATTTGCTCTTGGGGGATTAGGTATCATTTGGGGAGGAAGCATGTGTTCTGTGAGGTTGTTCGGCTATGTCCAAGTG TCGTTTACTAATGTACCCCTGCTGTTTGCTTTTGGTAATGTGATGTTGATGTTCTCCCCCTACCCACAACCATGCCCTTGAGGGTAGCAG GGCAGCAGCATACCAAAGAGATGTGCTGCAGGACTCCGGAGGCAGCCTGGGTGGGTGAGCCATGGGGCAGTTGACCTGGGTCTTGAAAGA GTCGGGAGTGACAAGCTCAGAGAGCATGAACTGATGCTGGCATGAAGGATTCCAGGAAGATCATGGAGACCTGGCTGGTAGCTGTAACAG AGATGGTGGAGTCCAAGGAAACAGCCTGTCTCTGGTGAATGGGACTTTCTTTGGTGGACACTTGGCACCAGCTCTGAGAGCCCTTCCCCT >4500_4500_18_ANKLE2-NHP2L1_ANKLE2_chr12_133324418_ENST00000539605_NHP2L1_chr22_42076368_ENST00000401959_length(amino acids)=480AA_BP=353 MGLGEMTMDALLARLKLLNPDDLREEIVKAGLKCGPITSTTRFIFEKKLAQALLEQGGRLSSFYHHEAGVTALSQDPQRILKPAEGNPTD QAGFSEDRDFGYSVGLNPPEEEAVTSKTCSVPPSDTDTYRAGATASKEPPLYYGVCPVYEDVPARNERIYVYENKKEALQAVKMIKGSRF KAFSTREDAEKFARGICDYFPSPSKTSLPLSPVKTAPLFSNDRLKDGLCLSESETVNKERANSYKNPRTQDLTAKLRKAVEKGEEDTFSD LIWSNPRYLIGSGDNPTIVQEGCRYNVMHVAAKENQASICQLTLDVLENPDFMRLMYPDDDEAMLQKRIRYVVDLYLNTPDKMTEADVNP KAYPLADAHLTKKLLDLVQQSCNYKQLRKGANEATKTLNRGISEFIVMAADAEPLEIILHLPLLCEDKNVPYVFVRSKQALGRACGVSRP -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ANKLE2-NHP2L1 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| Tgene | NHP2L1 | chr12:133324417 | chr22:42076368 | ENST00000215956 | 0 | 3 | 36_48 | 1.0 | 129.0 | U4 snRNA and U4atac snRNA | |
| Tgene | NHP2L1 | chr12:133324417 | chr22:42076368 | ENST00000355257 | 0 | 3 | 36_48 | 1.0 | 129.0 | U4 snRNA and U4atac snRNA | |
| Tgene | NHP2L1 | chr12:133324417 | chr22:42076368 | ENST00000401959 | 1 | 4 | 36_48 | 1.0 | 129.0 | U4 snRNA and U4atac snRNA | |
| Tgene | NHP2L1 | chr12:133324418 | chr22:42076368 | ENST00000215956 | 0 | 3 | 36_48 | 1.0 | 129.0 | U4 snRNA and U4atac snRNA | |
| Tgene | NHP2L1 | chr12:133324418 | chr22:42076368 | ENST00000355257 | 0 | 3 | 36_48 | 1.0 | 129.0 | U4 snRNA and U4atac snRNA | |
| Tgene | NHP2L1 | chr12:133324418 | chr22:42076368 | ENST00000401959 | 1 | 4 | 36_48 | 1.0 | 129.0 | U4 snRNA and U4atac snRNA |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ANKLE2-NHP2L1 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ANKLE2-NHP2L1 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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