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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANKRD10-ING1 (FusionGDB2 ID:4515)

Fusion Gene Summary for ANKRD10-ING1

check button Fusion gene summary
Fusion gene informationFusion gene name: ANKRD10-ING1
Fusion gene ID: 4515
HgeneTgene
Gene symbol

ANKRD10

ING1

Gene ID

55608

3621

Gene nameankyrin repeat domain 10inhibitor of growth family member 1
Synonyms-p24ING1c|p33|p33ING1|p33ING1b|p47|p47ING1a
Cytomap

13q34

13q34

Type of geneprotein-codingprotein-coding
Descriptionankyrin repeat domain-containing protein 10inhibitor of growth protein 1growth inhibitor ING1growth inhibitory protein ING1tumor suppressor ING1
Modification date2020031320200313
UniProtAcc.

Q9UK53

Ensembl transtripts involved in fusion geneENST00000267339, ENST00000310847, 
ENST00000375758, ENST00000489973, 
ENST00000464141, ENST00000375774, 
ENST00000375775, ENST00000333219, 
ENST00000338450, 
Fusion gene scores* DoF score9 X 8 X 4=2887 X 5 X 4=140
# samples 97
** MAII scorelog2(9/288*10)=-1.67807190511264
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(7/140*10)=-1
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANKRD10 [Title/Abstract] AND ING1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANKRD10(111567071)-ING1(111371575), # samples:1
Anticipated loss of major functional domain due to fusion event.ANKRD10-ING1 seems lost the major protein functional domain in Tgene partner, which is a epigenetic factor due to the frame-shifted ORF.
ANKRD10-ING1 seems lost the major protein functional domain in Tgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across ANKRD10 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across ING1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4STADTCGA-KB-A6F7ANKRD10chr13

111567071

-ING1chr13

111371575

+


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Fusion Gene ORF analysis for ANKRD10-ING1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-3UTRENST00000267339ENST00000464141ANKRD10chr13

111567071

-ING1chr13

111371575

+
5CDS-3UTRENST00000310847ENST00000464141ANKRD10chr13

111567071

-ING1chr13

111371575

+
5CDS-3UTRENST00000375758ENST00000464141ANKRD10chr13

111567071

-ING1chr13

111371575

+
5CDS-5UTRENST00000267339ENST00000375774ANKRD10chr13

111567071

-ING1chr13

111371575

+
5CDS-5UTRENST00000267339ENST00000375775ANKRD10chr13

111567071

-ING1chr13

111371575

+
5CDS-5UTRENST00000310847ENST00000375774ANKRD10chr13

111567071

-ING1chr13

111371575

+
5CDS-5UTRENST00000310847ENST00000375775ANKRD10chr13

111567071

-ING1chr13

111371575

+
5CDS-5UTRENST00000375758ENST00000375774ANKRD10chr13

111567071

-ING1chr13

111371575

+
5CDS-5UTRENST00000375758ENST00000375775ANKRD10chr13

111567071

-ING1chr13

111371575

+
Frame-shiftENST00000267339ENST00000333219ANKRD10chr13

111567071

-ING1chr13

111371575

+
Frame-shiftENST00000310847ENST00000333219ANKRD10chr13

111567071

-ING1chr13

111371575

+
Frame-shiftENST00000375758ENST00000333219ANKRD10chr13

111567071

-ING1chr13

111371575

+
In-frameENST00000267339ENST00000338450ANKRD10chr13

111567071

-ING1chr13

111371575

+
In-frameENST00000310847ENST00000338450ANKRD10chr13

111567071

-ING1chr13

111371575

+
In-frameENST00000375758ENST00000338450ANKRD10chr13

111567071

-ING1chr13

111371575

+
intron-3CDSENST00000489973ENST00000333219ANKRD10chr13

111567071

-ING1chr13

111371575

+
intron-3CDSENST00000489973ENST00000338450ANKRD10chr13

111567071

-ING1chr13

111371575

+
intron-3UTRENST00000489973ENST00000464141ANKRD10chr13

111567071

-ING1chr13

111371575

+
intron-5UTRENST00000489973ENST00000375774ANKRD10chr13

111567071

-ING1chr13

111371575

+
intron-5UTRENST00000489973ENST00000375775ANKRD10chr13

111567071

-ING1chr13

111371575

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000267339ANKRD10chr13111567071-ENST00000338450ING1chr13111371575+12923453081048246
ENST00000375758ANKRD10chr13111567071-ENST00000338450ING1chr13111371575+12923453081048246
ENST00000310847ANKRD10chr13111567071-ENST00000338450ING1chr13111371575+1229282245985246

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000267339ENST00000338450ANKRD10chr13111567071-ING1chr13111371575+0.0114808810.98851913
ENST00000375758ENST00000338450ANKRD10chr13111567071-ING1chr13111371575+0.0114808810.98851913
ENST00000310847ENST00000338450ANKRD10chr13111567071-ING1chr13111371575+0.0114751390.98852485

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Fusion Genomic Features for ANKRD10-ING1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANKRD10chr13111567071-ING1chr13111371575+6.87E-091
ANKRD10chr13111567071-ING1chr13111371575+6.87E-091

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANKRD10-ING1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr13:111567071/chr13:111371575)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.ING1

Q9UK53

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Cooperates with p53/TP53 in the negative regulatory pathway of cell growth by modulating p53-dependent transcriptional activation. Implicated as a tumor suppressor gene. {ECO:0000269|PubMed:9440695}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKRD10chr13:111567071chr13:111371575ENST00000267339-1621_5070421.0RepeatNote=ANK 1
HgeneANKRD10chr13:111567071chr13:111371575ENST00000310847-1521_5070221.0RepeatNote=ANK 1
HgeneANKRD10chr13:111567071chr13:111371575ENST00000375758-1721_5070659.0RepeatNote=ANK 1
TgeneING1chr13:111567071chr13:111371575ENST0000033321902405_42245280.0RegionPBR
TgeneING1chr13:111567071chr13:111371575ENST0000033845002405_4221236.0RegionPBR
TgeneING1chr13:111567071chr13:111371575ENST0000037577402405_422188423.0RegionPBR
TgeneING1chr13:111567071chr13:111371575ENST0000037577502405_4220211.0RegionPBR
TgeneING1chr13:111567071chr13:111371575ENST0000033321902353_40245280.0Zinc fingerPHD-type
TgeneING1chr13:111567071chr13:111371575ENST0000033845002353_4021236.0Zinc fingerPHD-type
TgeneING1chr13:111567071chr13:111371575ENST0000037577402353_402188423.0Zinc fingerPHD-type
TgeneING1chr13:111567071chr13:111371575ENST0000037577502353_4020211.0Zinc fingerPHD-type

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKRD10chr13:111567071chr13:111371575ENST00000267339-16124_15370421.0RepeatNote=ANK 4
HgeneANKRD10chr13:111567071chr13:111371575ENST00000267339-1657_8670421.0RepeatNote=ANK 2
HgeneANKRD10chr13:111567071chr13:111371575ENST00000267339-1691_12070421.0RepeatNote=ANK 3
HgeneANKRD10chr13:111567071chr13:111371575ENST00000310847-15124_15370221.0RepeatNote=ANK 4
HgeneANKRD10chr13:111567071chr13:111371575ENST00000310847-1557_8670221.0RepeatNote=ANK 2
HgeneANKRD10chr13:111567071chr13:111371575ENST00000310847-1591_12070221.0RepeatNote=ANK 3
HgeneANKRD10chr13:111567071chr13:111371575ENST00000375758-17124_15370659.0RepeatNote=ANK 4
HgeneANKRD10chr13:111567071chr13:111371575ENST00000375758-1757_8670659.0RepeatNote=ANK 2
HgeneANKRD10chr13:111567071chr13:111371575ENST00000375758-1791_12070659.0RepeatNote=ANK 3


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Fusion Gene Sequence for ANKRD10-ING1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4515_4515_1_ANKRD10-ING1_ANKRD10_chr13_111567071_ENST00000267339_ING1_chr13_111371575_ENST00000338450_length(transcript)=1292nt_BP=345nt
GCGCGCTCCGCTCGGCAGCCTGTGGGACGCGACCGCGGCGCTAGTCTCGTTCCTTTGTGCTGCGGCGGCGGCTTCTCGAGTCCTCCCCGA
CGCGTCCTCTAGGCCAGCGAGCCCCGCGCTCTCCGGTGACGGACCATGTCGGCGGCGGGAGCGGGCGCGGGCGTAGAGGCGGGCTTCTCC
AGCGAGGAGCTGCTCTCGCTCCGTTTCCCGCTGCACCGCGCCTGCCGCGACGGGGACCTGGCCACGCTCTGCTCGCTGCTGCAGCAGACA
CCCCACGCCCACCTGGCCTCTGAGGACTCCTTCTATGGCTGGACGCCCGTGCACTGGGCCGCGCATTTCGGCAAGAGATCCTGAAGGAGC
TAGACGAGTGCTACGAGCGCTTCAGTCGCGAGACAGACGGGGCGCAGAAGCGGCGGATGCTGCACTGTGTGCAGCGCGCGCTGATCCGCA
GCCAGGAGCTGGGCGACGAGAAGATCCAGATCGTGAGCCAGATGGTGGAGCTGGTGGAGAACCGCACGCGGCAGGTGGACAGCCACGTGG
AGCTGTTCGAGGCGCAGCAGGAGCTGGGCGACACAGCGGGCAACAGCGGCAAGGCTGGCGCGGACAGGCCCAAAGGCGAGGCGGCAGCGC
AGGCTGACAAGCCCAACAGCAAGCGCTCACGGCGGCAGCGCAACAACGAGAACCGTGAGAACGCGTCCAGCAACCACGACCACGACGACG
GCGCCTCGGGCACACCCAAGGAGAAGAAGGCCAAGACCTCCAAGAAGAAGAAGCGCTCCAAGGCCAAGGCGGAGCGAGAGGCGTCCCCTG
CCGACCTCCCCATCGACCCCAACGAACCCACGTACTGTCTGTGCAACCAGGTCTCCTATGGGGAGATGATCGGCTGCGACAACGACGAGT
GCCCCATCGAGTGGTTCCACTTCTCGTGCGTGGGGCTCAATCATAAACCCAAGGGCAAGTGGTACTGTCCCAAGTGCCGGGGGGAGAACG
AGAAGACCATGGACAAAGCCCTGGAGAAATCCAAAAAAGAGAGGGCTTACAACAGGTAGTTTGTGGACAGGCGCCTGGTGTGAGGAGGAC
AAAATAAACCGTGTATTTATTACATTGCTGCCTTTGTTGAGGTGCAAGGAGTGTAAAATGTATATTTTTAAAGAATGTTAGTAAAGGAAC
CATTCCTTTCATAGGGATGGCAGTGATTCTGTTTGCCTTTTGTTTTCATTGGTACACGTGTAACAAGAAAGTGGTCTGTGGATCAGCATT

>4515_4515_1_ANKRD10-ING1_ANKRD10_chr13_111567071_ENST00000267339_ING1_chr13_111371575_ENST00000338450_length(amino acids)=246AA_BP=12
MDARALGRAFRQEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTA
GNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYC

--------------------------------------------------------------
>4515_4515_2_ANKRD10-ING1_ANKRD10_chr13_111567071_ENST00000310847_ING1_chr13_111371575_ENST00000338450_length(transcript)=1229nt_BP=282nt
GGCGGCGGCTTCTCGAGTCCTCCCCGACGCGTCCTCTAGGCCAGCGAGCCCCGCGCTCTCCGGTGACGGACCATGTCGGCGGCGGGAGCG
GGCGCGGGCGTAGAGGCGGGCTTCTCCAGCGAGGAGCTGCTCTCGCTCCGTTTCCCGCTGCACCGCGCCTGCCGCGACGGGGACCTGGCC
ACGCTCTGCTCGCTGCTGCAGCAGACACCCCACGCCCACCTGGCCTCTGAGGACTCCTTCTATGGCTGGACGCCCGTGCACTGGGCCGCG
CATTTCGGCAAGAGATCCTGAAGGAGCTAGACGAGTGCTACGAGCGCTTCAGTCGCGAGACAGACGGGGCGCAGAAGCGGCGGATGCTGC
ACTGTGTGCAGCGCGCGCTGATCCGCAGCCAGGAGCTGGGCGACGAGAAGATCCAGATCGTGAGCCAGATGGTGGAGCTGGTGGAGAACC
GCACGCGGCAGGTGGACAGCCACGTGGAGCTGTTCGAGGCGCAGCAGGAGCTGGGCGACACAGCGGGCAACAGCGGCAAGGCTGGCGCGG
ACAGGCCCAAAGGCGAGGCGGCAGCGCAGGCTGACAAGCCCAACAGCAAGCGCTCACGGCGGCAGCGCAACAACGAGAACCGTGAGAACG
CGTCCAGCAACCACGACCACGACGACGGCGCCTCGGGCACACCCAAGGAGAAGAAGGCCAAGACCTCCAAGAAGAAGAAGCGCTCCAAGG
CCAAGGCGGAGCGAGAGGCGTCCCCTGCCGACCTCCCCATCGACCCCAACGAACCCACGTACTGTCTGTGCAACCAGGTCTCCTATGGGG
AGATGATCGGCTGCGACAACGACGAGTGCCCCATCGAGTGGTTCCACTTCTCGTGCGTGGGGCTCAATCATAAACCCAAGGGCAAGTGGT
ACTGTCCCAAGTGCCGGGGGGAGAACGAGAAGACCATGGACAAAGCCCTGGAGAAATCCAAAAAAGAGAGGGCTTACAACAGGTAGTTTG
TGGACAGGCGCCTGGTGTGAGGAGGACAAAATAAACCGTGTATTTATTACATTGCTGCCTTTGTTGAGGTGCAAGGAGTGTAAAATGTAT
ATTTTTAAAGAATGTTAGTAAAGGAACCATTCCTTTCATAGGGATGGCAGTGATTCTGTTTGCCTTTTGTTTTCATTGGTACACGTGTAA

>4515_4515_2_ANKRD10-ING1_ANKRD10_chr13_111567071_ENST00000310847_ING1_chr13_111371575_ENST00000338450_length(amino acids)=246AA_BP=12
MDARALGRAFRQEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTA
GNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYC

--------------------------------------------------------------
>4515_4515_3_ANKRD10-ING1_ANKRD10_chr13_111567071_ENST00000375758_ING1_chr13_111371575_ENST00000338450_length(transcript)=1292nt_BP=345nt
GCGCGCTCCGCTCGGCAGCCTGTGGGACGCGACCGCGGCGCTAGTCTCGTTCCTTTGTGCTGCGGCGGCGGCTTCTCGAGTCCTCCCCGA
CGCGTCCTCTAGGCCAGCGAGCCCCGCGCTCTCCGGTGACGGACCATGTCGGCGGCGGGAGCGGGCGCGGGCGTAGAGGCGGGCTTCTCC
AGCGAGGAGCTGCTCTCGCTCCGTTTCCCGCTGCACCGCGCCTGCCGCGACGGGGACCTGGCCACGCTCTGCTCGCTGCTGCAGCAGACA
CCCCACGCCCACCTGGCCTCTGAGGACTCCTTCTATGGCTGGACGCCCGTGCACTGGGCCGCGCATTTCGGCAAGAGATCCTGAAGGAGC
TAGACGAGTGCTACGAGCGCTTCAGTCGCGAGACAGACGGGGCGCAGAAGCGGCGGATGCTGCACTGTGTGCAGCGCGCGCTGATCCGCA
GCCAGGAGCTGGGCGACGAGAAGATCCAGATCGTGAGCCAGATGGTGGAGCTGGTGGAGAACCGCACGCGGCAGGTGGACAGCCACGTGG
AGCTGTTCGAGGCGCAGCAGGAGCTGGGCGACACAGCGGGCAACAGCGGCAAGGCTGGCGCGGACAGGCCCAAAGGCGAGGCGGCAGCGC
AGGCTGACAAGCCCAACAGCAAGCGCTCACGGCGGCAGCGCAACAACGAGAACCGTGAGAACGCGTCCAGCAACCACGACCACGACGACG
GCGCCTCGGGCACACCCAAGGAGAAGAAGGCCAAGACCTCCAAGAAGAAGAAGCGCTCCAAGGCCAAGGCGGAGCGAGAGGCGTCCCCTG
CCGACCTCCCCATCGACCCCAACGAACCCACGTACTGTCTGTGCAACCAGGTCTCCTATGGGGAGATGATCGGCTGCGACAACGACGAGT
GCCCCATCGAGTGGTTCCACTTCTCGTGCGTGGGGCTCAATCATAAACCCAAGGGCAAGTGGTACTGTCCCAAGTGCCGGGGGGAGAACG
AGAAGACCATGGACAAAGCCCTGGAGAAATCCAAAAAAGAGAGGGCTTACAACAGGTAGTTTGTGGACAGGCGCCTGGTGTGAGGAGGAC
AAAATAAACCGTGTATTTATTACATTGCTGCCTTTGTTGAGGTGCAAGGAGTGTAAAATGTATATTTTTAAAGAATGTTAGTAAAGGAAC
CATTCCTTTCATAGGGATGGCAGTGATTCTGTTTGCCTTTTGTTTTCATTGGTACACGTGTAACAAGAAAGTGGTCTGTGGATCAGCATT

>4515_4515_3_ANKRD10-ING1_ANKRD10_chr13_111567071_ENST00000375758_ING1_chr13_111371575_ENST00000338450_length(amino acids)=246AA_BP=12
MDARALGRAFRQEILKELDECYERFSRETDGAQKRRMLHCVQRALIRSQELGDEKIQIVSQMVELVENRTRQVDSHVELFEAQQELGDTA
GNSGKAGADRPKGEAAAQADKPNSKRSRRQRNNENRENASSNHDHDDGASGTPKEKKAKTSKKKKRSKAKAEREASPADLPIDPNEPTYC

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ANKRD10-ING1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANKRD10-ING1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANKRD10-ING1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource