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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABI2-CARF (FusionGDB2 ID:455)

Fusion Gene Summary for ABI2-CARF

check button Fusion gene summary
Fusion gene informationFusion gene name: ABI2-CARF
Fusion gene ID: 455
HgeneTgene
Gene symbol

ABI2

CARF

Gene ID

10152

79800

Gene nameabl interactor 2calcium responsive transcription factor
SynonymsABI-2|ABI2B|AIP-1|AIP1|AblBP3|SSH3BP2|argBP1|argBPIA|argBPIBALS2CR8|NYD-SP24
Cytomap

2q33.2

2q33.2

Type of geneprotein-codingprotein-coding
Descriptionabl interactor 2abelson interactor 2abl binding protein 3abl-interacting protein 1 (SH3-containing protein)abl-interactor protein 2barg protein tyrosine kinase-binding proteinarg-binding protein 1calcium-responsive transcription factoramyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 proteincalcium-response factortestis development protein NYD-SP24
Modification date2020032720200313
UniProtAcc

Q9NYB9

Q8N187

Ensembl transtripts involved in fusion geneENST00000430574, ENST00000261016, 
ENST00000261017, ENST00000261018, 
ENST00000295851, ENST00000422511, 
ENST00000424558, ENST00000430418, 
ENST00000402905, ENST00000320443, 
ENST00000414439, ENST00000428585, 
ENST00000434998, ENST00000438828, 
ENST00000444724, ENST00000456821, 
ENST00000471271, ENST00000545253, 
ENST00000545262, 
Fusion gene scores* DoF score14 X 7 X 8=7843 X 4 X 3=36
# samples 174
** MAII scorelog2(17/784*10)=-2.20531890797751
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/36*10)=0.15200309344505
effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs).
DoF>8 and MAII>0
Context

PubMed: ABI2 [Title/Abstract] AND CARF [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABI2(204267457)-CARF(203846278), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABI2

GO:0016601

Rac protein signal transduction

21107423

HgeneABI2

GO:0018108

peptidyl-tyrosine phosphorylation

17101133

HgeneABI2

GO:2000601

positive regulation of Arp2/3 complex-mediated actin nucleation

21107423

TgeneCARF

GO:0035865

cellular response to potassium ion

22174809

TgeneCARF

GO:0061400

positive regulation of transcription from RNA polymerase II promoter in response to calcium ion

11832226|22174809

TgeneCARF

GO:0071277

cellular response to calcium ion

11832226|22174809


check buttonFusion gene breakpoints across ABI2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CARF (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BRCATCGA-AN-A0FJ-01AABI2chr2

204267457

+CARFchr2

203846278

+


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Fusion Gene ORF analysis for ABI2-CARF

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
3UTR-3CDSENST00000430574ENST00000402905ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000320443ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000414439ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000428585ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000434998ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000438828ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000444724ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000456821ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000471271ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000545253ABI2chr2

204267457

+CARFchr2

203846278

+
3UTR-intronENST00000430574ENST00000545262ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000320443ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000414439ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000428585ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000434998ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000438828ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000444724ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000456821ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000471271ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000545253ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261016ENST00000545262ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000320443ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000414439ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000428585ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000434998ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000438828ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000444724ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000456821ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000471271ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000545253ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261017ENST00000545262ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000320443ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000414439ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000428585ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000434998ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000438828ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000444724ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000456821ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000471271ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000545253ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000261018ENST00000545262ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000320443ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000414439ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000428585ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000434998ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000438828ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000444724ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000456821ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000471271ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000545253ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000295851ENST00000545262ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000320443ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000414439ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000428585ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000434998ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000438828ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000444724ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000456821ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000471271ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000545253ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000422511ENST00000545262ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000320443ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000414439ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000428585ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000434998ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000438828ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000444724ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000456821ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000471271ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000545253ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000424558ENST00000545262ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000320443ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000414439ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000428585ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000434998ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000438828ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000444724ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000456821ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000471271ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000545253ABI2chr2

204267457

+CARFchr2

203846278

+
5CDS-intronENST00000430418ENST00000545262ABI2chr2

204267457

+CARFchr2

203846278

+
In-frameENST00000261016ENST00000402905ABI2chr2

204267457

+CARFchr2

203846278

+
In-frameENST00000261017ENST00000402905ABI2chr2

204267457

+CARFchr2

203846278

+
In-frameENST00000261018ENST00000402905ABI2chr2

204267457

+CARFchr2

203846278

+
In-frameENST00000295851ENST00000402905ABI2chr2

204267457

+CARFchr2

203846278

+
In-frameENST00000422511ENST00000402905ABI2chr2

204267457

+CARFchr2

203846278

+
In-frameENST00000424558ENST00000402905ABI2chr2

204267457

+CARFchr2

203846278

+
In-frameENST00000430418ENST00000402905ABI2chr2

204267457

+CARFchr2

203846278

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000295851ABI2chr2204267457+ENST00000402905CARFchr2203846278+554714882632107614
ENST00000261017ABI2chr2204267457+ENST00000402905CARFchr2203846278+528512262021845547
ENST00000430418ABI2chr2204267457+ENST00000402905CARFchr2203846278+52091150901769559
ENST00000424558ABI2chr2204267457+ENST00000402905CARFchr2203846278+53531294871913608
ENST00000261016ABI2chr2204267457+ENST00000402905CARFchr2203846278+524611873311806491
ENST00000422511ABI2chr2204267457+ENST00000402905CARFchr2203846278+51831124311743570
ENST00000261018ABI2chr2204267457+ENST00000402905CARFchr2203846278+4656597171216399

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000295851ENST00000402905ABI2chr2204267457+CARFchr2203846278+0.0001718670.9998281
ENST00000261017ENST00000402905ABI2chr2204267457+CARFchr2203846278+5.64E-050.9999436
ENST00000430418ENST00000402905ABI2chr2204267457+CARFchr2203846278+6.65E-050.9999335
ENST00000424558ENST00000402905ABI2chr2204267457+CARFchr2203846278+8.57E-050.9999143
ENST00000261016ENST00000402905ABI2chr2204267457+CARFchr2203846278+8.29E-050.99991715
ENST00000422511ENST00000402905ABI2chr2204267457+CARFchr2203846278+0.0001436570.99985635
ENST00000261018ENST00000402905ABI2chr2204267457+CARFchr2203846278+0.000263020.99973696

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Fusion Genomic Features for ABI2-CARF


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ABI2chr2204267457+CARFchr2203846277+8.31E-060.99999166
ABI2chr2204267457+CARFchr2203846277+8.31E-060.99999166

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ABI2-CARF


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:204267457/chr2:203846278)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABI2

Q9NYB9

CARF

Q8N187

FUNCTION: Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation (PubMed:21107423). Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge (PubMed:7590236, PubMed:8649853, PubMed:10498863). Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain (By similarity). In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth (By similarity). Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface (By similarity). Also required for nascent adherens junction assembly in epithelial cells (PubMed:15572692). {ECO:0000250|UniProtKB:P62484, ECO:0000269|PubMed:10498863, ECO:0000269|PubMed:15572692, ECO:0000269|PubMed:21107423, ECO:0000269|PubMed:7590236, ECO:0000269|PubMed:8649853}.FUNCTION: Acts as a transcriptional activator that mediates the calcium- and neuron-selective induction of BDNF exon III transcription. Binds to the consensus calcium-response element CaRE1 5'-CTATTTCGAG-3' sequence. {ECO:0000269|PubMed:11832226, ECO:0000269|PubMed:22174809}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABI2chr2:204267457chr2:203846278ENST00000261016+81045_107285402.0Domaint-SNARE coiled-coil homology
HgeneABI2chr2:204267457chr2:203846278ENST00000261017+71045_107330476.0Domaint-SNARE coiled-coil homology
HgeneABI2chr2:204267457chr2:203846278ENST00000424558+81045_107391508.0Domaint-SNARE coiled-coil homology

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABI2chr2:204267457chr2:203846278ENST00000261016+810172_423285402.0Compositional biasNote=Pro-rich
HgeneABI2chr2:204267457chr2:203846278ENST00000261017+710172_423330476.0Compositional biasNote=Pro-rich
HgeneABI2chr2:204267457chr2:203846278ENST00000424558+810172_423391508.0Compositional biasNote=Pro-rich
HgeneABI2chr2:204267457chr2:203846278ENST00000261016+810451_510285402.0DomainSH3
HgeneABI2chr2:204267457chr2:203846278ENST00000261017+710451_510330476.0DomainSH3
HgeneABI2chr2:204267457chr2:203846278ENST00000424558+810451_510391508.0DomainSH3


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Fusion Gene Sequence for ABI2-CARF


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>455_455_1_ABI2-CARF_ABI2_chr2_204267457_ENST00000261016_CARF_chr2_203846278_ENST00000402905_length(transcript)=5246nt_BP=1187nt
CTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTG
TATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTC
GACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGATAAGCAGAGAGCCCTAGAAGAAACC
AAAGCCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGTCCTGCAGATGCTGGATATCCAGGCA
TCCCAGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAGCAAATTAGAGGCGTTGATCTTGAGTCGACTTTTGTGACCAAATT
TGGAAACAATTGCAGTTTGAGATTGAATGAGACAGTTGATATTCATAAAGAGAAAGTTGCAAGAAGAGAAATTGGTATTTTGACTACCAA
TAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACGACCAGTTCGTTATATTAGAAAACCTATTGACTATACAAT
TCTAGATGATATTGGACATGGAGTAAAGGTGAGTACCCAGAACATGAAGATGGGTGGGCTGCCGCGTACAACACCTCCAACTCAGAAGCC
CCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGGCGGCACTCCCCCTATCGCACACTGGAGCCAGTGCGTCCTCCAGTGGTACCAAA
TGATTACGTACCTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCCTGTGAGGACAGCTTCTGTGAATCAAAGAAATCGAACTTA
CAGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAGTCGAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTAT
TGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGGTCATCCTGTACAGTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCC
CCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTTCACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTT
TTATAGCCAGAATCCAGGAAATTCACCAGGAGAATCAATTACCACCAAAGTGGAAACAAATCAGACCAGGGGTTCTTTGTCTCCTGAGCC
AACCCACTTGCTCTCCTCACTCTCCTCATTTCAGCCCAAAATATTTACACAACTACAGGGTTTGCAGTTACAACCAAGGTACACCTCTCC
TGATGAATCACCAGCTGTGGTATCAGTAAATAACCAGCCGTCCTCTAGTCCTTCAGGACTTCTGGATACAATAGGAAGTGCTGTAATGAA
TAATAATTCTCTACTGCTTGGTCAAAGTCATAGCCTTCAAAGAGATACATGCTTAACCCAAAACAATAGTACTGCCTCCACCATGGGTAA
CCTTCCAGAACCAGATCAAAATCTAGTTGCAATGGACGAGCTGGTAGAAGTTGGAGATGTTGAGGATACAGGGAATCTGGAAGGAACTGT
TCATCGGATTCTGTTGGGAGATGTGCAGACTATTCCAATACAGATTATAGACAACCACTCAGCTCTTATTGAAGAAAATCCAGAAAGTAC
CATTTCTGTGAGCCAAGTTAAACAAGAACCCAAAGAACCAGCATTGTCTATGGAAGCAAAAAAAACTGTGGACTATAAGAAATTATCTGC
TACATAAATTATTGAAGCTTTTCAGAATTTACAACTCTGGTGACTTCTGATGTCTTAGAAAGGAAGGTGAATATAGTCAAAGCGTGGCAT
TGAGATAATTGGACTGAAGACCAGTTTGATGAGAAGCTTTTATTTAAAACTGATATATTTGTTGCCAGTTCCATATTTTTACCTTCCTTA
AGAGATGTTTTACTCTTCTTATTTTGTATAATTTTTATGCTCTTTGATTATCTAATAAGGCCAGTATTTCAAAAGCTGTTCTGAATTTAT
CCACAGTAATATAGTCTGAACACAAATAGTTTACTTAACTTATCCTTGGAAATATTCAATTTTGGTTATTACAAAACAGAAAAGAACAAC
AGCAACAAAAACATTGTGTGAATGTATGTTTGTATGTGTGTATGTATATCATGAATTTTTTTTTTAAGTTCTGAAAAAGAACTTGTTCTC
TCCTTAAAGTTGTGAAGAAATTGTTAATTGCCAGACAGGTAAGAAAATGTTTATAATCTATCTCATTAAGAAAGATGAAGTATTAGATTT
TACATCATAACACAAAGTCCAGCAGCTACATCTGTGGAAACTGTGCAGTTGCATTTTAGCCTCTTCCCTTCCAATTTTTGTACTTTTAAC
TACAAACCAGTAGTATACTAATGGTTATCTAATAGAAATTTAAAGTGTCTTGGTAAGTACTGAGAATTTTTACTTGAATTAATCAGATAA
GCAACAGAAATCAACATATGTAGCATGGATTTGTGCTATATTGGAAGTAAAACACTATAGGCAGAAAGATGTAGAAATTAAGAGAATTGA
AAAAGAATAATAGAATTCCTTGGTGTTTACAGATAATTTGGAAAACTTTTTGATGACAGCAGAGGATTTTTTCCCCCTTATTTTGTAATG
AAGATCCAGCACTGGTTAAAAAATAATTTGATTTGTAGTTACATTTTTCTATGCCAGAGCTCTTACTGAATTGATGATATTAGGATTTCT
AGTATTTTAAGGTAAGTATTTATAGTTTAAAATTTAGTTTATATTTAAAACTTTAAAACATCTGATCTGGGATTTTTTTGTTAAGTAAGT
ATATTAACTTCAAATACCAAATTACTACTAAGCAGTATATTGATTATAAGCATCTGTTGTCTAAAGATTGGTACTAGGCTGGACATGGTG
GCTCACACCTGTAATCACAATACTTTGGGAGGCTGAGGTGGGTAGATAACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACGTGGTG
AAACCCTGTTTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGGGCACCTGTAATCCCAGCTACTTGGGAGGCTAAGGCAGGAGA
ATCGCTTGAACACCGGAGGCGGAGGTTGCAATGAGCCGAGATCGCGCCATTGCACTCCAGCCTGGGTGACAAGAGAAAAACTCCATCTCA
AAAAAAAAAAAAAGATTGGTAAACTAGAAATATCAACTATAATTGTCAGGAAATTAACCTAAAGGCTTTTGTTTCTCCAGAGACCATTTG
TGGGTATATTTTATATTTTAAAAATAAAGATTTTAAATGGATATCAATGTTTAATATTCAAAACATGCACAATATAATATCAAATTTAAC
CTTAATACTTTACATGAATATGAGTCACTTTTGGCTTTTCTAAGTCCAGCCTCCCATTCTTAATTGACTTGGTTTCAGGTACATGACATG
TATCTAAATATAAAGTACTGTTATAGTAGAGGTAGGTGGAATTCTAATATTCCCTGCTCTTTAGATTTATATTTTATTTAATATAAAGTT
TATTATTTATACCCTTTTTAATGCAAAGCTAATATTTAGTTATATGTATGATTTTTAATAAAAATTACTTTACTTTTTCCTATGAATTTA
AAACATTTGATGTTGGCATTTTATACAGGCAGGTTGCCAAATTTAATTATGTTACACTAAGTTAAACACAGCACTTAATTACCTCAAATC
CAGATTTCTCTTAATCTGTGTGTACATAAAAGGAATAAGTCCAAATTAATTTATAGTTTAGTGTTGCACTATAGGTAATATTCTTTTGTT
ATTTCTAGTTTTTATGGAATCCTTTTCTTTCAAGATTCTAAATAATAAATCGTTACGTCTCAATAGTGGTAATAGTGGTAATGGTTTATT
ATTAGCTGTTTCACCAATTGAACTACATTCTTTTGGAGACATTCCTTTCTTTTTTGATGTTGATTTGCAAAGGAGAAATGCTTGTTAATA
TACAAACTCTAGTCAGTTACCTGTGAGGATGAGATGTGTCAGAGGACTCAGACTTTGGTATAGTTAGAAAAATAATATTTTTCTCACTTG
ATTCTGTGTGAATGTCTCTTCTGATACTGTTTTTTAATCAGAAAGTTACAGAGCAACTTTCCCACAAACAAACCAATAAAACAAAACCCC
ACAAAAACCAAGAGCATGAAGAAAAGTTTAAATCCCTAATTATATACTCTTTTGGTTTTTAGGTAGAAACTGGAGCTATCAATATTTTCA
TGTAAGTATTTCAAGGAGTAGCTCTTTAAAAATGGTTTCTAAATTAGATTTTAAAAATTCATTGTCATCTAAATGCATGTTTAGTCACAA
TGTATCAGTATTGTGTTTAAAGGTGCTCAGCATCACTTTTTGAAAACTATGTTTACATATTTAAAATGTTTAATTATTTTGAAATGTATA
GGGTATTAAATACAAGCTTCTAAAATTTTCAGTATCTATATTGGCTTTCTCTAACAGCTCTACAGCAAAGTTTGACATGTTTTTTGTGTG
TGTCATGTATTGTAAGTTGTAATATCTGTAGGAGTGAGTTGGACATTCTAAATTAGCAGTAAAAAATTCACAATTACAGCTCAGCTTGTT
TATTCATTATAGTTTCCACATTTCCAACTTCCAAGTGAACTTTATATATACTACAGTGAATTATAGATAAATACAGCCATGGTGGACCTT
TCCCTCAATAGTGATTTTTTGTACAAACAGTTAGTATAATTAAAAGGAAAAGCTTTTATATTTTATGCAAGGTAAATGTTTCCTAAATGT
CACAAAAGTGATAGAAAACATAGCTTTTGGGATCTGGTCCTGCATTAGAGTTTCTAATTCTGAGACCCACCAGCTTGTGTTTCATCTTCT
TTATATCCTGTCAGAATACATACTTAATCATGTGGGTATGAGAAAGATGTTGTTTAACTTGTACCAGGTTTAAAAAAAGAGGTTTAAAAA
ATGTCTGTGCGTATATATATATATATATATATATATATATATATATATATAGCAACTTGATGTATAGTGTCCTTGTTACCATGTATTTTT
TTCATTAAAAATCCTGCTTTTTTTTTATACTTGTTAGTTTTCTTTTTATATTTTTCTTAGAGATAGTGGCAATTTTGTTCATCTTGAAGA

>455_455_1_ABI2-CARF_ABI2_chr2_204267457_ENST00000261016_CARF_chr2_203846278_ENST00000402905_length(amino acids)=491AA_BP=283
MSCRCWISRHPSYEGWNLQSIIFHKQIRGVDLESTFVTKFGNNCSLRLNETVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVR
YIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRT
ASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTS
LQNQMNGGPFYSQNPGNSPGESITTKVETNQTRGSLSPEPTHLLSSLSSFQPKIFTQLQGLQLQPRYTSPDESPAVVSVNNQPSSSPSGL
LDTIGSAVMNNNSLLLGQSHSLQRDTCLTQNNSTASTMGNLPEPDQNLVAMDELVEVGDVEDTGNLEGTVHRILLGDVQTIPIQIIDNHS

--------------------------------------------------------------
>455_455_2_ABI2-CARF_ABI2_chr2_204267457_ENST00000261017_CARF_chr2_203846278_ENST00000402905_length(transcript)=5285nt_BP=1226nt
GCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGT
CGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTG
CGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAAT
CCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGA
TAAGCAGAGAGCCCTAGAAGAAACCAAAGCCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGT
CCTGCAGATGCTGGATATCCAGGCATCCCAGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAACAGTTGATATTCATAAAGA
GAAAGTTGCAAGAAGAGAAATTGGTATTTTGACTACCAATAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACG
ACCAGTTCGTTATATTAGAAAACCTATTGACTATACAATTCTAGATGATATTGGACATGGAGTAAAGGTGAGTACCCAGAACATGAAGAT
GGGTGGGCTGCCGCGTACAACACCTCCAACTCAGAAGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGGCGGCACTCCCCCTA
TCGCACACTGGAGCCAGTGCGTCCTCCAGTGGTACCAAATGATTACGTACCTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCC
TGTGAGGACAGCTTCTGTGAATCAAAGAAATCGAACTTACAGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAG
TCGAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGGTCATCCTGTACA
GTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTTC
ACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGGAAATTCACCAGGAGAATCAATTACCACCAAAGT
GGAAACAAATCAGACCAGGGGTTCTTTGTCTCCTGAGCCAACCCACTTGCTCTCCTCACTCTCCTCATTTCAGCCCAAAATATTTACACA
ACTACAGGGTTTGCAGTTACAACCAAGGTACACCTCTCCTGATGAATCACCAGCTGTGGTATCAGTAAATAACCAGCCGTCCTCTAGTCC
TTCAGGACTTCTGGATACAATAGGAAGTGCTGTAATGAATAATAATTCTCTACTGCTTGGTCAAAGTCATAGCCTTCAAAGAGATACATG
CTTAACCCAAAACAATAGTACTGCCTCCACCATGGGTAACCTTCCAGAACCAGATCAAAATCTAGTTGCAATGGACGAGCTGGTAGAAGT
TGGAGATGTTGAGGATACAGGGAATCTGGAAGGAACTGTTCATCGGATTCTGTTGGGAGATGTGCAGACTATTCCAATACAGATTATAGA
CAACCACTCAGCTCTTATTGAAGAAAATCCAGAAAGTACCATTTCTGTGAGCCAAGTTAAACAAGAACCCAAAGAACCAGCATTGTCTAT
GGAAGCAAAAAAAACTGTGGACTATAAGAAATTATCTGCTACATAAATTATTGAAGCTTTTCAGAATTTACAACTCTGGTGACTTCTGAT
GTCTTAGAAAGGAAGGTGAATATAGTCAAAGCGTGGCATTGAGATAATTGGACTGAAGACCAGTTTGATGAGAAGCTTTTATTTAAAACT
GATATATTTGTTGCCAGTTCCATATTTTTACCTTCCTTAAGAGATGTTTTACTCTTCTTATTTTGTATAATTTTTATGCTCTTTGATTAT
CTAATAAGGCCAGTATTTCAAAAGCTGTTCTGAATTTATCCACAGTAATATAGTCTGAACACAAATAGTTTACTTAACTTATCCTTGGAA
ATATTCAATTTTGGTTATTACAAAACAGAAAAGAACAACAGCAACAAAAACATTGTGTGAATGTATGTTTGTATGTGTGTATGTATATCA
TGAATTTTTTTTTTAAGTTCTGAAAAAGAACTTGTTCTCTCCTTAAAGTTGTGAAGAAATTGTTAATTGCCAGACAGGTAAGAAAATGTT
TATAATCTATCTCATTAAGAAAGATGAAGTATTAGATTTTACATCATAACACAAAGTCCAGCAGCTACATCTGTGGAAACTGTGCAGTTG
CATTTTAGCCTCTTCCCTTCCAATTTTTGTACTTTTAACTACAAACCAGTAGTATACTAATGGTTATCTAATAGAAATTTAAAGTGTCTT
GGTAAGTACTGAGAATTTTTACTTGAATTAATCAGATAAGCAACAGAAATCAACATATGTAGCATGGATTTGTGCTATATTGGAAGTAAA
ACACTATAGGCAGAAAGATGTAGAAATTAAGAGAATTGAAAAAGAATAATAGAATTCCTTGGTGTTTACAGATAATTTGGAAAACTTTTT
GATGACAGCAGAGGATTTTTTCCCCCTTATTTTGTAATGAAGATCCAGCACTGGTTAAAAAATAATTTGATTTGTAGTTACATTTTTCTA
TGCCAGAGCTCTTACTGAATTGATGATATTAGGATTTCTAGTATTTTAAGGTAAGTATTTATAGTTTAAAATTTAGTTTATATTTAAAAC
TTTAAAACATCTGATCTGGGATTTTTTTGTTAAGTAAGTATATTAACTTCAAATACCAAATTACTACTAAGCAGTATATTGATTATAAGC
ATCTGTTGTCTAAAGATTGGTACTAGGCTGGACATGGTGGCTCACACCTGTAATCACAATACTTTGGGAGGCTGAGGTGGGTAGATAACC
TGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACGTGGTGAAACCCTGTTTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGGGC
ACCTGTAATCCCAGCTACTTGGGAGGCTAAGGCAGGAGAATCGCTTGAACACCGGAGGCGGAGGTTGCAATGAGCCGAGATCGCGCCATT
GCACTCCAGCCTGGGTGACAAGAGAAAAACTCCATCTCAAAAAAAAAAAAAAGATTGGTAAACTAGAAATATCAACTATAATTGTCAGGA
AATTAACCTAAAGGCTTTTGTTTCTCCAGAGACCATTTGTGGGTATATTTTATATTTTAAAAATAAAGATTTTAAATGGATATCAATGTT
TAATATTCAAAACATGCACAATATAATATCAAATTTAACCTTAATACTTTACATGAATATGAGTCACTTTTGGCTTTTCTAAGTCCAGCC
TCCCATTCTTAATTGACTTGGTTTCAGGTACATGACATGTATCTAAATATAAAGTACTGTTATAGTAGAGGTAGGTGGAATTCTAATATT
CCCTGCTCTTTAGATTTATATTTTATTTAATATAAAGTTTATTATTTATACCCTTTTTAATGCAAAGCTAATATTTAGTTATATGTATGA
TTTTTAATAAAAATTACTTTACTTTTTCCTATGAATTTAAAACATTTGATGTTGGCATTTTATACAGGCAGGTTGCCAAATTTAATTATG
TTACACTAAGTTAAACACAGCACTTAATTACCTCAAATCCAGATTTCTCTTAATCTGTGTGTACATAAAAGGAATAAGTCCAAATTAATT
TATAGTTTAGTGTTGCACTATAGGTAATATTCTTTTGTTATTTCTAGTTTTTATGGAATCCTTTTCTTTCAAGATTCTAAATAATAAATC
GTTACGTCTCAATAGTGGTAATAGTGGTAATGGTTTATTATTAGCTGTTTCACCAATTGAACTACATTCTTTTGGAGACATTCCTTTCTT
TTTTGATGTTGATTTGCAAAGGAGAAATGCTTGTTAATATACAAACTCTAGTCAGTTACCTGTGAGGATGAGATGTGTCAGAGGACTCAG
ACTTTGGTATAGTTAGAAAAATAATATTTTTCTCACTTGATTCTGTGTGAATGTCTCTTCTGATACTGTTTTTTAATCAGAAAGTTACAG
AGCAACTTTCCCACAAACAAACCAATAAAACAAAACCCCACAAAAACCAAGAGCATGAAGAAAAGTTTAAATCCCTAATTATATACTCTT
TTGGTTTTTAGGTAGAAACTGGAGCTATCAATATTTTCATGTAAGTATTTCAAGGAGTAGCTCTTTAAAAATGGTTTCTAAATTAGATTT
TAAAAATTCATTGTCATCTAAATGCATGTTTAGTCACAATGTATCAGTATTGTGTTTAAAGGTGCTCAGCATCACTTTTTGAAAACTATG
TTTACATATTTAAAATGTTTAATTATTTTGAAATGTATAGGGTATTAAATACAAGCTTCTAAAATTTTCAGTATCTATATTGGCTTTCTC
TAACAGCTCTACAGCAAAGTTTGACATGTTTTTTGTGTGTGTCATGTATTGTAAGTTGTAATATCTGTAGGAGTGAGTTGGACATTCTAA
ATTAGCAGTAAAAAATTCACAATTACAGCTCAGCTTGTTTATTCATTATAGTTTCCACATTTCCAACTTCCAAGTGAACTTTATATATAC
TACAGTGAATTATAGATAAATACAGCCATGGTGGACCTTTCCCTCAATAGTGATTTTTTGTACAAACAGTTAGTATAATTAAAAGGAAAA
GCTTTTATATTTTATGCAAGGTAAATGTTTCCTAAATGTCACAAAAGTGATAGAAAACATAGCTTTTGGGATCTGGTCCTGCATTAGAGT
TTCTAATTCTGAGACCCACCAGCTTGTGTTTCATCTTCTTTATATCCTGTCAGAATACATACTTAATCATGTGGGTATGAGAAAGATGTT
GTTTAACTTGTACCAGGTTTAAAAAAAGAGGTTTAAAAAATGTCTGTGCGTATATATATATATATATATATATATATATATATATATATA
GCAACTTGATGTATAGTGTCCTTGTTACCATGTATTTTTTTCATTAAAAATCCTGCTTTTTTTTTATACTTGTTAGTTTTCTTTTTATAT

>455_455_2_ABI2-CARF_ABI2_chr2_204267457_ENST00000261017_CARF_chr2_203846278_ENST00000402905_length(amino acids)=547AA_BP=339
MYEEEEEEDVKMAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQ
ASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTT
PPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSG
SVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPGNSPGESITTKVETNQTRG
SLSPEPTHLLSSLSSFQPKIFTQLQGLQLQPRYTSPDESPAVVSVNNQPSSSPSGLLDTIGSAVMNNNSLLLGQSHSLQRDTCLTQNNST
ASTMGNLPEPDQNLVAMDELVEVGDVEDTGNLEGTVHRILLGDVQTIPIQIIDNHSALIEENPESTISVSQVKQEPKEPALSMEAKKTVD

--------------------------------------------------------------
>455_455_3_ABI2-CARF_ABI2_chr2_204267457_ENST00000261018_CARF_chr2_203846278_ENST00000402905_length(transcript)=4656nt_BP=597nt
ATTTATGCATTAAGTGGTTGCTTAGATTTAAGGTGAGTACCCAGAACATGAAGATGGGTGGGCTGCCGCGTACAACACCTCCAACTCAGA
AGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAGTC
GAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGCCCCTGCTGGCTCTG
CTGGCACTCCTCCCCTTCCTGCTACTTCTGCATCTGCCCCTGCTCCTCTTGTTCCTGCTACTGTCCCTTCCTCCACTGCCCCAGACGCTG
CTGCTGGGGGTGCCCAGACCCTTGCTGATGGCTTCACTTCTCCAACTCCCCCTGTTGTTTCTTCCACTCCCCCTACAGGTCATCCTGTAC
AGTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTT
CACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGGAAATTCACCAGGAGAATCAATTACCACCAAAG
TGGAAACAAATCAGACCAGGGGTTCTTTGTCTCCTGAGCCAACCCACTTGCTCTCCTCACTCTCCTCATTTCAGCCCAAAATATTTACAC
AACTACAGGGTTTGCAGTTACAACCAAGGTACACCTCTCCTGATGAATCACCAGCTGTGGTATCAGTAAATAACCAGCCGTCCTCTAGTC
CTTCAGGACTTCTGGATACAATAGGAAGTGCTGTAATGAATAATAATTCTCTACTGCTTGGTCAAAGTCATAGCCTTCAAAGAGATACAT
GCTTAACCCAAAACAATAGTACTGCCTCCACCATGGGTAACCTTCCAGAACCAGATCAAAATCTAGTTGCAATGGACGAGCTGGTAGAAG
TTGGAGATGTTGAGGATACAGGGAATCTGGAAGGAACTGTTCATCGGATTCTGTTGGGAGATGTGCAGACTATTCCAATACAGATTATAG
ACAACCACTCAGCTCTTATTGAAGAAAATCCAGAAAGTACCATTTCTGTGAGCCAAGTTAAACAAGAACCCAAAGAACCAGCATTGTCTA
TGGAAGCAAAAAAAACTGTGGACTATAAGAAATTATCTGCTACATAAATTATTGAAGCTTTTCAGAATTTACAACTCTGGTGACTTCTGA
TGTCTTAGAAAGGAAGGTGAATATAGTCAAAGCGTGGCATTGAGATAATTGGACTGAAGACCAGTTTGATGAGAAGCTTTTATTTAAAAC
TGATATATTTGTTGCCAGTTCCATATTTTTACCTTCCTTAAGAGATGTTTTACTCTTCTTATTTTGTATAATTTTTATGCTCTTTGATTA
TCTAATAAGGCCAGTATTTCAAAAGCTGTTCTGAATTTATCCACAGTAATATAGTCTGAACACAAATAGTTTACTTAACTTATCCTTGGA
AATATTCAATTTTGGTTATTACAAAACAGAAAAGAACAACAGCAACAAAAACATTGTGTGAATGTATGTTTGTATGTGTGTATGTATATC
ATGAATTTTTTTTTTAAGTTCTGAAAAAGAACTTGTTCTCTCCTTAAAGTTGTGAAGAAATTGTTAATTGCCAGACAGGTAAGAAAATGT
TTATAATCTATCTCATTAAGAAAGATGAAGTATTAGATTTTACATCATAACACAAAGTCCAGCAGCTACATCTGTGGAAACTGTGCAGTT
GCATTTTAGCCTCTTCCCTTCCAATTTTTGTACTTTTAACTACAAACCAGTAGTATACTAATGGTTATCTAATAGAAATTTAAAGTGTCT
TGGTAAGTACTGAGAATTTTTACTTGAATTAATCAGATAAGCAACAGAAATCAACATATGTAGCATGGATTTGTGCTATATTGGAAGTAA
AACACTATAGGCAGAAAGATGTAGAAATTAAGAGAATTGAAAAAGAATAATAGAATTCCTTGGTGTTTACAGATAATTTGGAAAACTTTT
TGATGACAGCAGAGGATTTTTTCCCCCTTATTTTGTAATGAAGATCCAGCACTGGTTAAAAAATAATTTGATTTGTAGTTACATTTTTCT
ATGCCAGAGCTCTTACTGAATTGATGATATTAGGATTTCTAGTATTTTAAGGTAAGTATTTATAGTTTAAAATTTAGTTTATATTTAAAA
CTTTAAAACATCTGATCTGGGATTTTTTTGTTAAGTAAGTATATTAACTTCAAATACCAAATTACTACTAAGCAGTATATTGATTATAAG
CATCTGTTGTCTAAAGATTGGTACTAGGCTGGACATGGTGGCTCACACCTGTAATCACAATACTTTGGGAGGCTGAGGTGGGTAGATAAC
CTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACGTGGTGAAACCCTGTTTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGGG
CACCTGTAATCCCAGCTACTTGGGAGGCTAAGGCAGGAGAATCGCTTGAACACCGGAGGCGGAGGTTGCAATGAGCCGAGATCGCGCCAT
TGCACTCCAGCCTGGGTGACAAGAGAAAAACTCCATCTCAAAAAAAAAAAAAAGATTGGTAAACTAGAAATATCAACTATAATTGTCAGG
AAATTAACCTAAAGGCTTTTGTTTCTCCAGAGACCATTTGTGGGTATATTTTATATTTTAAAAATAAAGATTTTAAATGGATATCAATGT
TTAATATTCAAAACATGCACAATATAATATCAAATTTAACCTTAATACTTTACATGAATATGAGTCACTTTTGGCTTTTCTAAGTCCAGC
CTCCCATTCTTAATTGACTTGGTTTCAGGTACATGACATGTATCTAAATATAAAGTACTGTTATAGTAGAGGTAGGTGGAATTCTAATAT
TCCCTGCTCTTTAGATTTATATTTTATTTAATATAAAGTTTATTATTTATACCCTTTTTAATGCAAAGCTAATATTTAGTTATATGTATG
ATTTTTAATAAAAATTACTTTACTTTTTCCTATGAATTTAAAACATTTGATGTTGGCATTTTATACAGGCAGGTTGCCAAATTTAATTAT
GTTACACTAAGTTAAACACAGCACTTAATTACCTCAAATCCAGATTTCTCTTAATCTGTGTGTACATAAAAGGAATAAGTCCAAATTAAT
TTATAGTTTAGTGTTGCACTATAGGTAATATTCTTTTGTTATTTCTAGTTTTTATGGAATCCTTTTCTTTCAAGATTCTAAATAATAAAT
CGTTACGTCTCAATAGTGGTAATAGTGGTAATGGTTTATTATTAGCTGTTTCACCAATTGAACTACATTCTTTTGGAGACATTCCTTTCT
TTTTTGATGTTGATTTGCAAAGGAGAAATGCTTGTTAATATACAAACTCTAGTCAGTTACCTGTGAGGATGAGATGTGTCAGAGGACTCA
GACTTTGGTATAGTTAGAAAAATAATATTTTTCTCACTTGATTCTGTGTGAATGTCTCTTCTGATACTGTTTTTTAATCAGAAAGTTACA
GAGCAACTTTCCCACAAACAAACCAATAAAACAAAACCCCACAAAAACCAAGAGCATGAAGAAAAGTTTAAATCCCTAATTATATACTCT
TTTGGTTTTTAGGTAGAAACTGGAGCTATCAATATTTTCATGTAAGTATTTCAAGGAGTAGCTCTTTAAAAATGGTTTCTAAATTAGATT
TTAAAAATTCATTGTCATCTAAATGCATGTTTAGTCACAATGTATCAGTATTGTGTTTAAAGGTGCTCAGCATCACTTTTTGAAAACTAT
GTTTACATATTTAAAATGTTTAATTATTTTGAAATGTATAGGGTATTAAATACAAGCTTCTAAAATTTTCAGTATCTATATTGGCTTTCT
CTAACAGCTCTACAGCAAAGTTTGACATGTTTTTTGTGTGTGTCATGTATTGTAAGTTGTAATATCTGTAGGAGTGAGTTGGACATTCTA
AATTAGCAGTAAAAAATTCACAATTACAGCTCAGCTTGTTTATTCATTATAGTTTCCACATTTCCAACTTCCAAGTGAACTTTATATATA
CTACAGTGAATTATAGATAAATACAGCCATGGTGGACCTTTCCCTCAATAGTGATTTTTTGTACAAACAGTTAGTATAATTAAAAGGAAA
AGCTTTTATATTTTATGCAAGGTAAATGTTTCCTAAATGTCACAAAAGTGATAGAAAACATAGCTTTTGGGATCTGGTCCTGCATTAGAG
TTTCTAATTCTGAGACCCACCAGCTTGTGTTTCATCTTCTTTATATCCTGTCAGAATACATACTTAATCATGTGGGTATGAGAAAGATGT
TGTTTAACTTGTACCAGGTTTAAAAAAAGAGGTTTAAAAAATGTCTGTGCGTATATATATATATATATATATATATATATATATATATAT
AGCAACTTGATGTATAGTGTCCTTGTTACCATGTATTTTTTTCATTAAAAATCCTGCTTTTTTTTTATACTTGTTAGTTTTCTTTTTATA

>455_455_3_ABI2-CARF_ABI2_chr2_204267457_ENST00000261018_CARF_chr2_203846278_ENST00000402905_length(amino acids)=399AA_BP=191
MLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPL
PATSASAPAPLVPATVPSSTAPDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQ
NQMNGGPFYSQNPGNSPGESITTKVETNQTRGSLSPEPTHLLSSLSSFQPKIFTQLQGLQLQPRYTSPDESPAVVSVNNQPSSSPSGLLD
TIGSAVMNNNSLLLGQSHSLQRDTCLTQNNSTASTMGNLPEPDQNLVAMDELVEVGDVEDTGNLEGTVHRILLGDVQTIPIQIIDNHSAL

--------------------------------------------------------------
>455_455_4_ABI2-CARF_ABI2_chr2_204267457_ENST00000295851_CARF_chr2_203846278_ENST00000402905_length(transcript)=5547nt_BP=1488nt
CCGGCGGCGCGGGCGAGGGTGGGAATCTTTTTCGGGCTCCCGGGGGCGGAGGGAAGGGAGCGCGCGTGCGCGCGCCCGGCCGGCCGTCGC
CGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGTCGCGCGCTGGGGCTGTTTCTCGCTCCTTC
CGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATG
AGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACA
GCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGATAAGCAGAGAGCCCTAGAAGAAACCAAAG
CCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGTCCTGCAGATGCTGGATATCCAGGCATCCC
AGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAACAGTTGATATTCATAAAGAGAAAGTTGCAAGAAGAGAAATTGGTATTT
TGACTACCAATAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACGACCAGTTCGTTATATTAGAAAACCTATTG
ACTATACAATTCTAGATGATATTGGACATGGAGTAAAGTGGTTGCTTAGATTTAAGGTGAGTACCCAGAACATGAAGATGGGTGGGCTGC
CGCGTACAACACCTCCAACTCAGAAGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGGCGGCACTCCCCCTATCGCACACTGG
AGCCAGTGCGTCCTCCAGTGGTACCAAATGATTACGTACCTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCCTGTGAGGACAG
CTTCTGTGAATCAAAGAAATCGAACTTACAGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAGTCGAGAGAACA
GTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGCCCCTGCTGGCTCTGCTGGCACTC
CTCCCCTTCCTGCTACTTCTGCATCTGCCCCTGCTCCTCTTGTTCCTGCTACTGTCCCTTCCTCCACTGCCCCAGACGCTGCTGCTGGGG
GTGCCCAGACCCTTGCTGATGGCTTCACTTCTCCAACTCCCCCTGTTGTTTCTTCCACTCCCCCTACAGGTCATCCTGTACAGTTCTACA
GCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTTCACAAACAA
GCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGGAAATTCACCAGGAGAATCAATTACCACCAAAGTGGAAACAA
ATCAGACCAGGGGTTCTTTGTCTCCTGAGCCAACCCACTTGCTCTCCTCACTCTCCTCATTTCAGCCCAAAATATTTACACAACTACAGG
GTTTGCAGTTACAACCAAGGTACACCTCTCCTGATGAATCACCAGCTGTGGTATCAGTAAATAACCAGCCGTCCTCTAGTCCTTCAGGAC
TTCTGGATACAATAGGAAGTGCTGTAATGAATAATAATTCTCTACTGCTTGGTCAAAGTCATAGCCTTCAAAGAGATACATGCTTAACCC
AAAACAATAGTACTGCCTCCACCATGGGTAACCTTCCAGAACCAGATCAAAATCTAGTTGCAATGGACGAGCTGGTAGAAGTTGGAGATG
TTGAGGATACAGGGAATCTGGAAGGAACTGTTCATCGGATTCTGTTGGGAGATGTGCAGACTATTCCAATACAGATTATAGACAACCACT
CAGCTCTTATTGAAGAAAATCCAGAAAGTACCATTTCTGTGAGCCAAGTTAAACAAGAACCCAAAGAACCAGCATTGTCTATGGAAGCAA
AAAAAACTGTGGACTATAAGAAATTATCTGCTACATAAATTATTGAAGCTTTTCAGAATTTACAACTCTGGTGACTTCTGATGTCTTAGA
AAGGAAGGTGAATATAGTCAAAGCGTGGCATTGAGATAATTGGACTGAAGACCAGTTTGATGAGAAGCTTTTATTTAAAACTGATATATT
TGTTGCCAGTTCCATATTTTTACCTTCCTTAAGAGATGTTTTACTCTTCTTATTTTGTATAATTTTTATGCTCTTTGATTATCTAATAAG
GCCAGTATTTCAAAAGCTGTTCTGAATTTATCCACAGTAATATAGTCTGAACACAAATAGTTTACTTAACTTATCCTTGGAAATATTCAA
TTTTGGTTATTACAAAACAGAAAAGAACAACAGCAACAAAAACATTGTGTGAATGTATGTTTGTATGTGTGTATGTATATCATGAATTTT
TTTTTTAAGTTCTGAAAAAGAACTTGTTCTCTCCTTAAAGTTGTGAAGAAATTGTTAATTGCCAGACAGGTAAGAAAATGTTTATAATCT
ATCTCATTAAGAAAGATGAAGTATTAGATTTTACATCATAACACAAAGTCCAGCAGCTACATCTGTGGAAACTGTGCAGTTGCATTTTAG
CCTCTTCCCTTCCAATTTTTGTACTTTTAACTACAAACCAGTAGTATACTAATGGTTATCTAATAGAAATTTAAAGTGTCTTGGTAAGTA
CTGAGAATTTTTACTTGAATTAATCAGATAAGCAACAGAAATCAACATATGTAGCATGGATTTGTGCTATATTGGAAGTAAAACACTATA
GGCAGAAAGATGTAGAAATTAAGAGAATTGAAAAAGAATAATAGAATTCCTTGGTGTTTACAGATAATTTGGAAAACTTTTTGATGACAG
CAGAGGATTTTTTCCCCCTTATTTTGTAATGAAGATCCAGCACTGGTTAAAAAATAATTTGATTTGTAGTTACATTTTTCTATGCCAGAG
CTCTTACTGAATTGATGATATTAGGATTTCTAGTATTTTAAGGTAAGTATTTATAGTTTAAAATTTAGTTTATATTTAAAACTTTAAAAC
ATCTGATCTGGGATTTTTTTGTTAAGTAAGTATATTAACTTCAAATACCAAATTACTACTAAGCAGTATATTGATTATAAGCATCTGTTG
TCTAAAGATTGGTACTAGGCTGGACATGGTGGCTCACACCTGTAATCACAATACTTTGGGAGGCTGAGGTGGGTAGATAACCTGAGGTCA
GGAGTTCGAGACCAGCCTGGCCAACGTGGTGAAACCCTGTTTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGGGCACCTGTAA
TCCCAGCTACTTGGGAGGCTAAGGCAGGAGAATCGCTTGAACACCGGAGGCGGAGGTTGCAATGAGCCGAGATCGCGCCATTGCACTCCA
GCCTGGGTGACAAGAGAAAAACTCCATCTCAAAAAAAAAAAAAAGATTGGTAAACTAGAAATATCAACTATAATTGTCAGGAAATTAACC
TAAAGGCTTTTGTTTCTCCAGAGACCATTTGTGGGTATATTTTATATTTTAAAAATAAAGATTTTAAATGGATATCAATGTTTAATATTC
AAAACATGCACAATATAATATCAAATTTAACCTTAATACTTTACATGAATATGAGTCACTTTTGGCTTTTCTAAGTCCAGCCTCCCATTC
TTAATTGACTTGGTTTCAGGTACATGACATGTATCTAAATATAAAGTACTGTTATAGTAGAGGTAGGTGGAATTCTAATATTCCCTGCTC
TTTAGATTTATATTTTATTTAATATAAAGTTTATTATTTATACCCTTTTTAATGCAAAGCTAATATTTAGTTATATGTATGATTTTTAAT
AAAAATTACTTTACTTTTTCCTATGAATTTAAAACATTTGATGTTGGCATTTTATACAGGCAGGTTGCCAAATTTAATTATGTTACACTA
AGTTAAACACAGCACTTAATTACCTCAAATCCAGATTTCTCTTAATCTGTGTGTACATAAAAGGAATAAGTCCAAATTAATTTATAGTTT
AGTGTTGCACTATAGGTAATATTCTTTTGTTATTTCTAGTTTTTATGGAATCCTTTTCTTTCAAGATTCTAAATAATAAATCGTTACGTC
TCAATAGTGGTAATAGTGGTAATGGTTTATTATTAGCTGTTTCACCAATTGAACTACATTCTTTTGGAGACATTCCTTTCTTTTTTGATG
TTGATTTGCAAAGGAGAAATGCTTGTTAATATACAAACTCTAGTCAGTTACCTGTGAGGATGAGATGTGTCAGAGGACTCAGACTTTGGT
ATAGTTAGAAAAATAATATTTTTCTCACTTGATTCTGTGTGAATGTCTCTTCTGATACTGTTTTTTAATCAGAAAGTTACAGAGCAACTT
TCCCACAAACAAACCAATAAAACAAAACCCCACAAAAACCAAGAGCATGAAGAAAAGTTTAAATCCCTAATTATATACTCTTTTGGTTTT
TAGGTAGAAACTGGAGCTATCAATATTTTCATGTAAGTATTTCAAGGAGTAGCTCTTTAAAAATGGTTTCTAAATTAGATTTTAAAAATT
CATTGTCATCTAAATGCATGTTTAGTCACAATGTATCAGTATTGTGTTTAAAGGTGCTCAGCATCACTTTTTGAAAACTATGTTTACATA
TTTAAAATGTTTAATTATTTTGAAATGTATAGGGTATTAAATACAAGCTTCTAAAATTTTCAGTATCTATATTGGCTTTCTCTAACAGCT
CTACAGCAAAGTTTGACATGTTTTTTGTGTGTGTCATGTATTGTAAGTTGTAATATCTGTAGGAGTGAGTTGGACATTCTAAATTAGCAG
TAAAAAATTCACAATTACAGCTCAGCTTGTTTATTCATTATAGTTTCCACATTTCCAACTTCCAAGTGAACTTTATATATACTACAGTGA
ATTATAGATAAATACAGCCATGGTGGACCTTTCCCTCAATAGTGATTTTTTGTACAAACAGTTAGTATAATTAAAAGGAAAAGCTTTTAT
ATTTTATGCAAGGTAAATGTTTCCTAAATGTCACAAAAGTGATAGAAAACATAGCTTTTGGGATCTGGTCCTGCATTAGAGTTTCTAATT
CTGAGACCCACCAGCTTGTGTTTCATCTTCTTTATATCCTGTCAGAATACATACTTAATCATGTGGGTATGAGAAAGATGTTGTTTAACT
TGTACCAGGTTTAAAAAAAGAGGTTTAAAAAATGTCTGTGCGTATATATATATATATATATATATATATATATATATATATAGCAACTTG
ATGTATAGTGTCCTTGTTACCATGTATTTTTTTCATTAAAAATCCTGCTTTTTTTTTATACTTGTTAGTTTTCTTTTTATATTTTTCTTA

>455_455_4_ABI2-CARF_ABI2_chr2_204267457_ENST00000295851_CARF_chr2_203846278_ENST00000402905_length(amino acids)=614AA_BP=406
MYEEEEEEDVKMAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQ
ASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMG
GLPRTTPPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSR
ENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPLPATSASAPAPLVPATVPSSTAPDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQ
FYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPGNSPGESITTKVETNQTRGSLSPEPTHLLSSLSSFQPKIFTQ
LQGLQLQPRYTSPDESPAVVSVNNQPSSSPSGLLDTIGSAVMNNNSLLLGQSHSLQRDTCLTQNNSTASTMGNLPEPDQNLVAMDELVEV

--------------------------------------------------------------
>455_455_5_ABI2-CARF_ABI2_chr2_204267457_ENST00000422511_CARF_chr2_203846278_ENST00000402905_length(transcript)=5183nt_BP=1124nt
GTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTT
CGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGATAAGCAGAGAGCCCTAGAAGAAAC
CAAAGCCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGTCCTGCAGATGCTGGATATCCAGGC
ATCCCAGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAACAGTTGATATTCATAAAGAGAAAGTTGCAAGAAGAGAAATTGG
TATTTTGACTACCAATAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACGACCAGTTCGTTATATTAGAAAACC
TATTGACTATACAATTCTAGATGATATTGGACATGGAGTAAAGTGGTTGCTTAGATTTAAGGTGAGTACCCAGAACATGAAGATGGGTGG
GCTGCCGCGTACAACACCTCCAACTCAGAAGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGGCGGCACTCCCCCTATCGCAC
ACTGGAGCCAGTGCGTCCTCCAGTGGTACCAAATGATTACGTACCTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCCTGTGAG
GACAGCTTCTGTGAATCAAAGAAATCGAACTTACAGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAGTCGAGA
GAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGACGCTGCTGCTGGGGGTGC
CCAGACCCTTGCTGATGGCTTCACTTCTCCAACTCCCCCTGTTGTTTCTTCCACTCCCCCTACAGGTCATCCTGTACAGTTCTACAGCAT
GAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTTCACAAACAAGCCT
TCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGGAAATTCACCAGGAGAATCAATTACCACCAAAGTGGAAACAAATCA
GACCAGGGGTTCTTTGTCTCCTGAGCCAACCCACTTGCTCTCCTCACTCTCCTCATTTCAGCCCAAAATATTTACACAACTACAGGGTTT
GCAGTTACAACCAAGGTACACCTCTCCTGATGAATCACCAGCTGTGGTATCAGTAAATAACCAGCCGTCCTCTAGTCCTTCAGGACTTCT
GGATACAATAGGAAGTGCTGTAATGAATAATAATTCTCTACTGCTTGGTCAAAGTCATAGCCTTCAAAGAGATACATGCTTAACCCAAAA
CAATAGTACTGCCTCCACCATGGGTAACCTTCCAGAACCAGATCAAAATCTAGTTGCAATGGACGAGCTGGTAGAAGTTGGAGATGTTGA
GGATACAGGGAATCTGGAAGGAACTGTTCATCGGATTCTGTTGGGAGATGTGCAGACTATTCCAATACAGATTATAGACAACCACTCAGC
TCTTATTGAAGAAAATCCAGAAAGTACCATTTCTGTGAGCCAAGTTAAACAAGAACCCAAAGAACCAGCATTGTCTATGGAAGCAAAAAA
AACTGTGGACTATAAGAAATTATCTGCTACATAAATTATTGAAGCTTTTCAGAATTTACAACTCTGGTGACTTCTGATGTCTTAGAAAGG
AAGGTGAATATAGTCAAAGCGTGGCATTGAGATAATTGGACTGAAGACCAGTTTGATGAGAAGCTTTTATTTAAAACTGATATATTTGTT
GCCAGTTCCATATTTTTACCTTCCTTAAGAGATGTTTTACTCTTCTTATTTTGTATAATTTTTATGCTCTTTGATTATCTAATAAGGCCA
GTATTTCAAAAGCTGTTCTGAATTTATCCACAGTAATATAGTCTGAACACAAATAGTTTACTTAACTTATCCTTGGAAATATTCAATTTT
GGTTATTACAAAACAGAAAAGAACAACAGCAACAAAAACATTGTGTGAATGTATGTTTGTATGTGTGTATGTATATCATGAATTTTTTTT
TTAAGTTCTGAAAAAGAACTTGTTCTCTCCTTAAAGTTGTGAAGAAATTGTTAATTGCCAGACAGGTAAGAAAATGTTTATAATCTATCT
CATTAAGAAAGATGAAGTATTAGATTTTACATCATAACACAAAGTCCAGCAGCTACATCTGTGGAAACTGTGCAGTTGCATTTTAGCCTC
TTCCCTTCCAATTTTTGTACTTTTAACTACAAACCAGTAGTATACTAATGGTTATCTAATAGAAATTTAAAGTGTCTTGGTAAGTACTGA
GAATTTTTACTTGAATTAATCAGATAAGCAACAGAAATCAACATATGTAGCATGGATTTGTGCTATATTGGAAGTAAAACACTATAGGCA
GAAAGATGTAGAAATTAAGAGAATTGAAAAAGAATAATAGAATTCCTTGGTGTTTACAGATAATTTGGAAAACTTTTTGATGACAGCAGA
GGATTTTTTCCCCCTTATTTTGTAATGAAGATCCAGCACTGGTTAAAAAATAATTTGATTTGTAGTTACATTTTTCTATGCCAGAGCTCT
TACTGAATTGATGATATTAGGATTTCTAGTATTTTAAGGTAAGTATTTATAGTTTAAAATTTAGTTTATATTTAAAACTTTAAAACATCT
GATCTGGGATTTTTTTGTTAAGTAAGTATATTAACTTCAAATACCAAATTACTACTAAGCAGTATATTGATTATAAGCATCTGTTGTCTA
AAGATTGGTACTAGGCTGGACATGGTGGCTCACACCTGTAATCACAATACTTTGGGAGGCTGAGGTGGGTAGATAACCTGAGGTCAGGAG
TTCGAGACCAGCCTGGCCAACGTGGTGAAACCCTGTTTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGGGCACCTGTAATCCC
AGCTACTTGGGAGGCTAAGGCAGGAGAATCGCTTGAACACCGGAGGCGGAGGTTGCAATGAGCCGAGATCGCGCCATTGCACTCCAGCCT
GGGTGACAAGAGAAAAACTCCATCTCAAAAAAAAAAAAAAGATTGGTAAACTAGAAATATCAACTATAATTGTCAGGAAATTAACCTAAA
GGCTTTTGTTTCTCCAGAGACCATTTGTGGGTATATTTTATATTTTAAAAATAAAGATTTTAAATGGATATCAATGTTTAATATTCAAAA
CATGCACAATATAATATCAAATTTAACCTTAATACTTTACATGAATATGAGTCACTTTTGGCTTTTCTAAGTCCAGCCTCCCATTCTTAA
TTGACTTGGTTTCAGGTACATGACATGTATCTAAATATAAAGTACTGTTATAGTAGAGGTAGGTGGAATTCTAATATTCCCTGCTCTTTA
GATTTATATTTTATTTAATATAAAGTTTATTATTTATACCCTTTTTAATGCAAAGCTAATATTTAGTTATATGTATGATTTTTAATAAAA
ATTACTTTACTTTTTCCTATGAATTTAAAACATTTGATGTTGGCATTTTATACAGGCAGGTTGCCAAATTTAATTATGTTACACTAAGTT
AAACACAGCACTTAATTACCTCAAATCCAGATTTCTCTTAATCTGTGTGTACATAAAAGGAATAAGTCCAAATTAATTTATAGTTTAGTG
TTGCACTATAGGTAATATTCTTTTGTTATTTCTAGTTTTTATGGAATCCTTTTCTTTCAAGATTCTAAATAATAAATCGTTACGTCTCAA
TAGTGGTAATAGTGGTAATGGTTTATTATTAGCTGTTTCACCAATTGAACTACATTCTTTTGGAGACATTCCTTTCTTTTTTGATGTTGA
TTTGCAAAGGAGAAATGCTTGTTAATATACAAACTCTAGTCAGTTACCTGTGAGGATGAGATGTGTCAGAGGACTCAGACTTTGGTATAG
TTAGAAAAATAATATTTTTCTCACTTGATTCTGTGTGAATGTCTCTTCTGATACTGTTTTTTAATCAGAAAGTTACAGAGCAACTTTCCC
ACAAACAAACCAATAAAACAAAACCCCACAAAAACCAAGAGCATGAAGAAAAGTTTAAATCCCTAATTATATACTCTTTTGGTTTTTAGG
TAGAAACTGGAGCTATCAATATTTTCATGTAAGTATTTCAAGGAGTAGCTCTTTAAAAATGGTTTCTAAATTAGATTTTAAAAATTCATT
GTCATCTAAATGCATGTTTAGTCACAATGTATCAGTATTGTGTTTAAAGGTGCTCAGCATCACTTTTTGAAAACTATGTTTACATATTTA
AAATGTTTAATTATTTTGAAATGTATAGGGTATTAAATACAAGCTTCTAAAATTTTCAGTATCTATATTGGCTTTCTCTAACAGCTCTAC
AGCAAAGTTTGACATGTTTTTTGTGTGTGTCATGTATTGTAAGTTGTAATATCTGTAGGAGTGAGTTGGACATTCTAAATTAGCAGTAAA
AAATTCACAATTACAGCTCAGCTTGTTTATTCATTATAGTTTCCACATTTCCAACTTCCAAGTGAACTTTATATATACTACAGTGAATTA
TAGATAAATACAGCCATGGTGGACCTTTCCCTCAATAGTGATTTTTTGTACAAACAGTTAGTATAATTAAAAGGAAAAGCTTTTATATTT
TATGCAAGGTAAATGTTTCCTAAATGTCACAAAAGTGATAGAAAACATAGCTTTTGGGATCTGGTCCTGCATTAGAGTTTCTAATTCTGA
GACCCACCAGCTTGTGTTTCATCTTCTTTATATCCTGTCAGAATACATACTTAATCATGTGGGTATGAGAAAGATGTTGTTTAACTTGTA
CCAGGTTTAAAAAAAGAGGTTTAAAAAATGTCTGTGCGTATATATATATATATATATATATATATATATATATATATAGCAACTTGATGT
ATAGTGTCCTTGTTACCATGTATTTTTTTCATTAAAAATCCTGCTTTTTTTTTATACTTGTTAGTTTTCTTTTTATATTTTTCTTAGAGA

>455_455_5_ABI2-CARF_ABI2_chr2_204267457_ENST00000422511_CARF_chr2_203846278_ENST00000402905_length(amino acids)=570AA_BP=362
MAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQASQLRRMESSI
NHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKWLLRFKVSTQNMKMGGLPRTTPPTQK
PPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSGSVGVP
IAVPTPSPPSVFPDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFY
SQNPGNSPGESITTKVETNQTRGSLSPEPTHLLSSLSSFQPKIFTQLQGLQLQPRYTSPDESPAVVSVNNQPSSSPSGLLDTIGSAVMNN
NSLLLGQSHSLQRDTCLTQNNSTASTMGNLPEPDQNLVAMDELVEVGDVEDTGNLEGTVHRILLGDVQTIPIQIIDNHSALIEENPESTI

--------------------------------------------------------------
>455_455_6_ABI2-CARF_ABI2_chr2_204267457_ENST00000424558_CARF_chr2_203846278_ENST00000402905_length(transcript)=5353nt_BP=1294nt
CTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTG
TATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTC
GACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGATAAGCAGAGAGCCCTAGAAGAAACC
AAAGCCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGTCCTGCAGATGCTGGATATCCAGGCA
TCCCAGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAACAGTTGATATTCATAAAGAGAAAGTTGCAAGAAGAGAAATTGGT
ATTTTGACTACCAATAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACGACCAGTTCGTTATATTAGAAAACCT
ATTGACTATACAATTCTAGATGATATTGGACATGGAGTAAAGGTGAGTACCCAGAACATGAAGATGGGTGGGCTGCCGCGTACAACACCT
CCAACTCAGAAGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGGCGGCACTCCCCCTATCGCACACTGGAGCCAGTGCGTCCT
CCAGTGGTACCAAATGATTACGTACCTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCCTGTGAGGACAGCTTCTGTGAATCAA
AGAAATCGAACTTACAGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAGTCGAGAGAACAGTGGAAGTGGTAGT
GTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGCCCCTGCTGGCTCTGCTGGCACTCCTCCCCTTCCTGCT
ACTTCTGCATCTGCCCCTGCTCCTCTTGTTCCTGCTACTGTCCCTTCCTCCACTGCCCCAGACGCTGCTGCTGGGGGTGCCCAGACCCTT
GCTGATGGCTTCACTTCTCCAACTCCCCCTGTTGTTTCTTCCACTCCCCCTACAGGTCATCCTGTACAGTTCTACAGCATGAATAGGCCT
GCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTTCACAAACAAGCCTTCAGAATCAG
ATGAATGGAGGACCTTTTTATAGCCAGAATCCAGGAAATTCACCAGGAGAATCAATTACCACCAAAGTGGAAACAAATCAGACCAGGGGT
TCTTTGTCTCCTGAGCCAACCCACTTGCTCTCCTCACTCTCCTCATTTCAGCCCAAAATATTTACACAACTACAGGGTTTGCAGTTACAA
CCAAGGTACACCTCTCCTGATGAATCACCAGCTGTGGTATCAGTAAATAACCAGCCGTCCTCTAGTCCTTCAGGACTTCTGGATACAATA
GGAAGTGCTGTAATGAATAATAATTCTCTACTGCTTGGTCAAAGTCATAGCCTTCAAAGAGATACATGCTTAACCCAAAACAATAGTACT
GCCTCCACCATGGGTAACCTTCCAGAACCAGATCAAAATCTAGTTGCAATGGACGAGCTGGTAGAAGTTGGAGATGTTGAGGATACAGGG
AATCTGGAAGGAACTGTTCATCGGATTCTGTTGGGAGATGTGCAGACTATTCCAATACAGATTATAGACAACCACTCAGCTCTTATTGAA
GAAAATCCAGAAAGTACCATTTCTGTGAGCCAAGTTAAACAAGAACCCAAAGAACCAGCATTGTCTATGGAAGCAAAAAAAACTGTGGAC
TATAAGAAATTATCTGCTACATAAATTATTGAAGCTTTTCAGAATTTACAACTCTGGTGACTTCTGATGTCTTAGAAAGGAAGGTGAATA
TAGTCAAAGCGTGGCATTGAGATAATTGGACTGAAGACCAGTTTGATGAGAAGCTTTTATTTAAAACTGATATATTTGTTGCCAGTTCCA
TATTTTTACCTTCCTTAAGAGATGTTTTACTCTTCTTATTTTGTATAATTTTTATGCTCTTTGATTATCTAATAAGGCCAGTATTTCAAA
AGCTGTTCTGAATTTATCCACAGTAATATAGTCTGAACACAAATAGTTTACTTAACTTATCCTTGGAAATATTCAATTTTGGTTATTACA
AAACAGAAAAGAACAACAGCAACAAAAACATTGTGTGAATGTATGTTTGTATGTGTGTATGTATATCATGAATTTTTTTTTTAAGTTCTG
AAAAAGAACTTGTTCTCTCCTTAAAGTTGTGAAGAAATTGTTAATTGCCAGACAGGTAAGAAAATGTTTATAATCTATCTCATTAAGAAA
GATGAAGTATTAGATTTTACATCATAACACAAAGTCCAGCAGCTACATCTGTGGAAACTGTGCAGTTGCATTTTAGCCTCTTCCCTTCCA
ATTTTTGTACTTTTAACTACAAACCAGTAGTATACTAATGGTTATCTAATAGAAATTTAAAGTGTCTTGGTAAGTACTGAGAATTTTTAC
TTGAATTAATCAGATAAGCAACAGAAATCAACATATGTAGCATGGATTTGTGCTATATTGGAAGTAAAACACTATAGGCAGAAAGATGTA
GAAATTAAGAGAATTGAAAAAGAATAATAGAATTCCTTGGTGTTTACAGATAATTTGGAAAACTTTTTGATGACAGCAGAGGATTTTTTC
CCCCTTATTTTGTAATGAAGATCCAGCACTGGTTAAAAAATAATTTGATTTGTAGTTACATTTTTCTATGCCAGAGCTCTTACTGAATTG
ATGATATTAGGATTTCTAGTATTTTAAGGTAAGTATTTATAGTTTAAAATTTAGTTTATATTTAAAACTTTAAAACATCTGATCTGGGAT
TTTTTTGTTAAGTAAGTATATTAACTTCAAATACCAAATTACTACTAAGCAGTATATTGATTATAAGCATCTGTTGTCTAAAGATTGGTA
CTAGGCTGGACATGGTGGCTCACACCTGTAATCACAATACTTTGGGAGGCTGAGGTGGGTAGATAACCTGAGGTCAGGAGTTCGAGACCA
GCCTGGCCAACGTGGTGAAACCCTGTTTCTACTAAAAATACAAAAATTAGCTGGGTGTGGTGGTGGGCACCTGTAATCCCAGCTACTTGG
GAGGCTAAGGCAGGAGAATCGCTTGAACACCGGAGGCGGAGGTTGCAATGAGCCGAGATCGCGCCATTGCACTCCAGCCTGGGTGACAAG
AGAAAAACTCCATCTCAAAAAAAAAAAAAAGATTGGTAAACTAGAAATATCAACTATAATTGTCAGGAAATTAACCTAAAGGCTTTTGTT
TCTCCAGAGACCATTTGTGGGTATATTTTATATTTTAAAAATAAAGATTTTAAATGGATATCAATGTTTAATATTCAAAACATGCACAAT
ATAATATCAAATTTAACCTTAATACTTTACATGAATATGAGTCACTTTTGGCTTTTCTAAGTCCAGCCTCCCATTCTTAATTGACTTGGT
TTCAGGTACATGACATGTATCTAAATATAAAGTACTGTTATAGTAGAGGTAGGTGGAATTCTAATATTCCCTGCTCTTTAGATTTATATT
TTATTTAATATAAAGTTTATTATTTATACCCTTTTTAATGCAAAGCTAATATTTAGTTATATGTATGATTTTTAATAAAAATTACTTTAC
TTTTTCCTATGAATTTAAAACATTTGATGTTGGCATTTTATACAGGCAGGTTGCCAAATTTAATTATGTTACACTAAGTTAAACACAGCA
CTTAATTACCTCAAATCCAGATTTCTCTTAATCTGTGTGTACATAAAAGGAATAAGTCCAAATTAATTTATAGTTTAGTGTTGCACTATA
GGTAATATTCTTTTGTTATTTCTAGTTTTTATGGAATCCTTTTCTTTCAAGATTCTAAATAATAAATCGTTACGTCTCAATAGTGGTAAT
AGTGGTAATGGTTTATTATTAGCTGTTTCACCAATTGAACTACATTCTTTTGGAGACATTCCTTTCTTTTTTGATGTTGATTTGCAAAGG
AGAAATGCTTGTTAATATACAAACTCTAGTCAGTTACCTGTGAGGATGAGATGTGTCAGAGGACTCAGACTTTGGTATAGTTAGAAAAAT
AATATTTTTCTCACTTGATTCTGTGTGAATGTCTCTTCTGATACTGTTTTTTAATCAGAAAGTTACAGAGCAACTTTCCCACAAACAAAC
CAATAAAACAAAACCCCACAAAAACCAAGAGCATGAAGAAAAGTTTAAATCCCTAATTATATACTCTTTTGGTTTTTAGGTAGAAACTGG
AGCTATCAATATTTTCATGTAAGTATTTCAAGGAGTAGCTCTTTAAAAATGGTTTCTAAATTAGATTTTAAAAATTCATTGTCATCTAAA
TGCATGTTTAGTCACAATGTATCAGTATTGTGTTTAAAGGTGCTCAGCATCACTTTTTGAAAACTATGTTTACATATTTAAAATGTTTAA
TTATTTTGAAATGTATAGGGTATTAAATACAAGCTTCTAAAATTTTCAGTATCTATATTGGCTTTCTCTAACAGCTCTACAGCAAAGTTT
GACATGTTTTTTGTGTGTGTCATGTATTGTAAGTTGTAATATCTGTAGGAGTGAGTTGGACATTCTAAATTAGCAGTAAAAAATTCACAA
TTACAGCTCAGCTTGTTTATTCATTATAGTTTCCACATTTCCAACTTCCAAGTGAACTTTATATATACTACAGTGAATTATAGATAAATA
CAGCCATGGTGGACCTTTCCCTCAATAGTGATTTTTTGTACAAACAGTTAGTATAATTAAAAGGAAAAGCTTTTATATTTTATGCAAGGT
AAATGTTTCCTAAATGTCACAAAAGTGATAGAAAACATAGCTTTTGGGATCTGGTCCTGCATTAGAGTTTCTAATTCTGAGACCCACCAG
CTTGTGTTTCATCTTCTTTATATCCTGTCAGAATACATACTTAATCATGTGGGTATGAGAAAGATGTTGTTTAACTTGTACCAGGTTTAA
AAAAAGAGGTTTAAAAAATGTCTGTGCGTATATATATATATATATATATATATATATATATATATATAGCAACTTGATGTATAGTGTCCT
TGTTACCATGTATTTTTTTCATTAAAAATCCTGCTTTTTTTTTATACTTGTTAGTTTTCTTTTTATATTTTTCTTAGAGATAGTGGCAAT

>455_455_6_ABI2-CARF_ABI2_chr2_204267457_ENST00000424558_CARF_chr2_203846278_ENST00000402905_length(amino acids)=608AA_BP=400
MYEEEEEEDVKMAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQ
ASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTT
PPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSG
SVGVPIAVPTPSPPSVFPAPAGSAGTPPLPATSASAPAPLVPATVPSSTAPDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQFYSMNR
PASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPGNSPGESITTKVETNQTRGSLSPEPTHLLSSLSSFQPKIFTQLQGLQL
QPRYTSPDESPAVVSVNNQPSSSPSGLLDTIGSAVMNNNSLLLGQSHSLQRDTCLTQNNSTASTMGNLPEPDQNLVAMDELVEVGDVEDT

--------------------------------------------------------------
>455_455_7_ABI2-CARF_ABI2_chr2_204267457_ENST00000430418_CARF_chr2_203846278_ENST00000402905_length(transcript)=5209nt_BP=1150nt
CTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGAC
CTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTC
TTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGATAAGCAGAGAGCCCTAGAAGAA
ACCAAAGCCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGTCCTGCAGATGCTGGATATCCAG
GCATCCCAGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAACAGTTGATATTCATAAAGAGAAAGTTGCAAGAAGAGAAATT
GGTATTTTGACTACCAATAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACGACCAGTTCGTTATATTAGAAAA
CCTATTGACTATACAATTCTAGATGATATTGGACATGGAGTAAAGGTGAGTACCCAGAACATGAAGATGGGTGGGCTGCCGCGTACAACA
CCTCCAACTCAGAAGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGT
CGGAGCAGCAGTCGAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGCC
CCTGCTGGCTCTGCTGGCACTCCTCCCCTTCCTGCTACTTCTGCATCTGCCCCTGCTCCTCTTGTTCCTGCTACTGTCCCTTCCTCCACT
GCCCCAGACGCTGCTGCTGGGGGTGCCCAGACCCTTGCTGATGGCTTCACTTCTCCAACTCCCCCTGTTGTTTCTTCCACTCCCCCTACA
GGTCATCCTGTACAGTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCT
CCTTCCATTACTTCACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGGAAATTCACCAGGAGAATCA
ATTACCACCAAAGTGGAAACAAATCAGACCAGGGGTTCTTTGTCTCCTGAGCCAACCCACTTGCTCTCCTCACTCTCCTCATTTCAGCCC
AAAATATTTACACAACTACAGGGTTTGCAGTTACAACCAAGGTACACCTCTCCTGATGAATCACCAGCTGTGGTATCAGTAAATAACCAG
CCGTCCTCTAGTCCTTCAGGACTTCTGGATACAATAGGAAGTGCTGTAATGAATAATAATTCTCTACTGCTTGGTCAAAGTCATAGCCTT
CAAAGAGATACATGCTTAACCCAAAACAATAGTACTGCCTCCACCATGGGTAACCTTCCAGAACCAGATCAAAATCTAGTTGCAATGGAC
GAGCTGGTAGAAGTTGGAGATGTTGAGGATACAGGGAATCTGGAAGGAACTGTTCATCGGATTCTGTTGGGAGATGTGCAGACTATTCCA
ATACAGATTATAGACAACCACTCAGCTCTTATTGAAGAAAATCCAGAAAGTACCATTTCTGTGAGCCAAGTTAAACAAGAACCCAAAGAA
CCAGCATTGTCTATGGAAGCAAAAAAAACTGTGGACTATAAGAAATTATCTGCTACATAAATTATTGAAGCTTTTCAGAATTTACAACTC
TGGTGACTTCTGATGTCTTAGAAAGGAAGGTGAATATAGTCAAAGCGTGGCATTGAGATAATTGGACTGAAGACCAGTTTGATGAGAAGC
TTTTATTTAAAACTGATATATTTGTTGCCAGTTCCATATTTTTACCTTCCTTAAGAGATGTTTTACTCTTCTTATTTTGTATAATTTTTA
TGCTCTTTGATTATCTAATAAGGCCAGTATTTCAAAAGCTGTTCTGAATTTATCCACAGTAATATAGTCTGAACACAAATAGTTTACTTA
ACTTATCCTTGGAAATATTCAATTTTGGTTATTACAAAACAGAAAAGAACAACAGCAACAAAAACATTGTGTGAATGTATGTTTGTATGT
GTGTATGTATATCATGAATTTTTTTTTTAAGTTCTGAAAAAGAACTTGTTCTCTCCTTAAAGTTGTGAAGAAATTGTTAATTGCCAGACA
GGTAAGAAAATGTTTATAATCTATCTCATTAAGAAAGATGAAGTATTAGATTTTACATCATAACACAAAGTCCAGCAGCTACATCTGTGG
AAACTGTGCAGTTGCATTTTAGCCTCTTCCCTTCCAATTTTTGTACTTTTAACTACAAACCAGTAGTATACTAATGGTTATCTAATAGAA
ATTTAAAGTGTCTTGGTAAGTACTGAGAATTTTTACTTGAATTAATCAGATAAGCAACAGAAATCAACATATGTAGCATGGATTTGTGCT
ATATTGGAAGTAAAACACTATAGGCAGAAAGATGTAGAAATTAAGAGAATTGAAAAAGAATAATAGAATTCCTTGGTGTTTACAGATAAT
TTGGAAAACTTTTTGATGACAGCAGAGGATTTTTTCCCCCTTATTTTGTAATGAAGATCCAGCACTGGTTAAAAAATAATTTGATTTGTA
GTTACATTTTTCTATGCCAGAGCTCTTACTGAATTGATGATATTAGGATTTCTAGTATTTTAAGGTAAGTATTTATAGTTTAAAATTTAG
TTTATATTTAAAACTTTAAAACATCTGATCTGGGATTTTTTTGTTAAGTAAGTATATTAACTTCAAATACCAAATTACTACTAAGCAGTA
TATTGATTATAAGCATCTGTTGTCTAAAGATTGGTACTAGGCTGGACATGGTGGCTCACACCTGTAATCACAATACTTTGGGAGGCTGAG
GTGGGTAGATAACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACGTGGTGAAACCCTGTTTCTACTAAAAATACAAAAATTAGCTGG
GTGTGGTGGTGGGCACCTGTAATCCCAGCTACTTGGGAGGCTAAGGCAGGAGAATCGCTTGAACACCGGAGGCGGAGGTTGCAATGAGCC
GAGATCGCGCCATTGCACTCCAGCCTGGGTGACAAGAGAAAAACTCCATCTCAAAAAAAAAAAAAAGATTGGTAAACTAGAAATATCAAC
TATAATTGTCAGGAAATTAACCTAAAGGCTTTTGTTTCTCCAGAGACCATTTGTGGGTATATTTTATATTTTAAAAATAAAGATTTTAAA
TGGATATCAATGTTTAATATTCAAAACATGCACAATATAATATCAAATTTAACCTTAATACTTTACATGAATATGAGTCACTTTTGGCTT
TTCTAAGTCCAGCCTCCCATTCTTAATTGACTTGGTTTCAGGTACATGACATGTATCTAAATATAAAGTACTGTTATAGTAGAGGTAGGT
GGAATTCTAATATTCCCTGCTCTTTAGATTTATATTTTATTTAATATAAAGTTTATTATTTATACCCTTTTTAATGCAAAGCTAATATTT
AGTTATATGTATGATTTTTAATAAAAATTACTTTACTTTTTCCTATGAATTTAAAACATTTGATGTTGGCATTTTATACAGGCAGGTTGC
CAAATTTAATTATGTTACACTAAGTTAAACACAGCACTTAATTACCTCAAATCCAGATTTCTCTTAATCTGTGTGTACATAAAAGGAATA
AGTCCAAATTAATTTATAGTTTAGTGTTGCACTATAGGTAATATTCTTTTGTTATTTCTAGTTTTTATGGAATCCTTTTCTTTCAAGATT
CTAAATAATAAATCGTTACGTCTCAATAGTGGTAATAGTGGTAATGGTTTATTATTAGCTGTTTCACCAATTGAACTACATTCTTTTGGA
GACATTCCTTTCTTTTTTGATGTTGATTTGCAAAGGAGAAATGCTTGTTAATATACAAACTCTAGTCAGTTACCTGTGAGGATGAGATGT
GTCAGAGGACTCAGACTTTGGTATAGTTAGAAAAATAATATTTTTCTCACTTGATTCTGTGTGAATGTCTCTTCTGATACTGTTTTTTAA
TCAGAAAGTTACAGAGCAACTTTCCCACAAACAAACCAATAAAACAAAACCCCACAAAAACCAAGAGCATGAAGAAAAGTTTAAATCCCT
AATTATATACTCTTTTGGTTTTTAGGTAGAAACTGGAGCTATCAATATTTTCATGTAAGTATTTCAAGGAGTAGCTCTTTAAAAATGGTT
TCTAAATTAGATTTTAAAAATTCATTGTCATCTAAATGCATGTTTAGTCACAATGTATCAGTATTGTGTTTAAAGGTGCTCAGCATCACT
TTTTGAAAACTATGTTTACATATTTAAAATGTTTAATTATTTTGAAATGTATAGGGTATTAAATACAAGCTTCTAAAATTTTCAGTATCT
ATATTGGCTTTCTCTAACAGCTCTACAGCAAAGTTTGACATGTTTTTTGTGTGTGTCATGTATTGTAAGTTGTAATATCTGTAGGAGTGA
GTTGGACATTCTAAATTAGCAGTAAAAAATTCACAATTACAGCTCAGCTTGTTTATTCATTATAGTTTCCACATTTCCAACTTCCAAGTG
AACTTTATATATACTACAGTGAATTATAGATAAATACAGCCATGGTGGACCTTTCCCTCAATAGTGATTTTTTGTACAAACAGTTAGTAT
AATTAAAAGGAAAAGCTTTTATATTTTATGCAAGGTAAATGTTTCCTAAATGTCACAAAAGTGATAGAAAACATAGCTTTTGGGATCTGG
TCCTGCATTAGAGTTTCTAATTCTGAGACCCACCAGCTTGTGTTTCATCTTCTTTATATCCTGTCAGAATACATACTTAATCATGTGGGT
ATGAGAAAGATGTTGTTTAACTTGTACCAGGTTTAAAAAAAGAGGTTTAAAAAATGTCTGTGCGTATATATATATATATATATATATATA
TATATATATATATAGCAACTTGATGTATAGTGTCCTTGTTACCATGTATTTTTTTCATTAAAAATCCTGCTTTTTTTTTATACTTGTTAG

>455_455_7_ABI2-CARF_ABI2_chr2_204267457_ENST00000430418_CARF_chr2_203846278_ENST00000402905_length(amino acids)=559AA_BP=351
MYEEEEEEDVKMAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQ
ASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTT
PPTQKPPSPPMSGKGTLGSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPLPATSASAPAPLVPATVPSST
APDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPGNSPGES
ITTKVETNQTRGSLSPEPTHLLSSLSSFQPKIFTQLQGLQLQPRYTSPDESPAVVSVNNQPSSSPSGLLDTIGSAVMNNNSLLLGQSHSL
QRDTCLTQNNSTASTMGNLPEPDQNLVAMDELVEVGDVEDTGNLEGTVHRILLGDVQTIPIQIIDNHSALIEENPESTISVSQVKQEPKE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ABI2-CARF


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABI2-CARF


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABI2-CARF


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource