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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ABI2-CHMP1A (FusionGDB2 ID:456)

Fusion Gene Summary for ABI2-CHMP1A

check button Fusion gene summary
Fusion gene informationFusion gene name: ABI2-CHMP1A
Fusion gene ID: 456
HgeneTgene
Gene symbol

ABI2

CHMP1A

Gene ID

10152

5119

Gene nameabl interactor 2charged multivesicular body protein 1A
SynonymsABI-2|ABI2B|AIP-1|AIP1|AblBP3|SSH3BP2|argBP1|argBPIA|argBPIBCHMP1|PCH8|PCOLN3|PRSM1|VPS46-1|VPS46A
Cytomap

2q33.2

16q24.3

Type of geneprotein-codingprotein-coding
Descriptionabl interactor 2abelson interactor 2abl binding protein 3abl-interacting protein 1 (SH3-containing protein)abl-interactor protein 2barg protein tyrosine kinase-binding proteinarg-binding protein 1charged multivesicular body protein 1acharged multivesicular body protein 1/chromatin modifying protein 1chromatin modifying protein 1Aprocollagen (type III) N-endopeptidaseprotease, metallo, 1, 33kDvacuolar protein sorting-associated protein 46-1
Modification date2020032720200313
UniProtAcc

Q9NYB9

Q9HD42

Ensembl transtripts involved in fusion geneENST00000261016, ENST00000261017, 
ENST00000261018, ENST00000295851, 
ENST00000422511, ENST00000424558, 
ENST00000430418, ENST00000430574, 
ENST00000547614, ENST00000253475, 
ENST00000397901, ENST00000535997, 
ENST00000550102, 
Fusion gene scores* DoF score14 X 7 X 8=78445 X 11 X 21=10395
# samples 1748
** MAII scorelog2(17/784*10)=-2.20531890797751
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(48/10395*10)=-4.43671154213721
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ABI2 [Title/Abstract] AND CHMP1A [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointABI2(204291992)-CHMP1A(89713739), # samples:1
Anticipated loss of major functional domain due to fusion event.ABI2-CHMP1A seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ABI2-CHMP1A seems lost the major protein functional domain in Hgene partner, which is a tumor suppressor due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneABI2

GO:0016601

Rac protein signal transduction

21107423

HgeneABI2

GO:0018108

peptidyl-tyrosine phosphorylation

17101133

HgeneABI2

GO:2000601

positive regulation of Arp2/3 complex-mediated actin nucleation

21107423

TgeneCHMP1A

GO:0007076

mitotic chromosome condensation

11559747

TgeneCHMP1A

GO:0016192

vesicle-mediated transport

11559748

TgeneCHMP1A

GO:0016458

gene silencing

11559747

TgeneCHMP1A

GO:0045892

negative regulation of transcription, DNA-templated

11559747


check buttonFusion gene breakpoints across ABI2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CHMP1A (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4PCPGTCGA-S7-A7WO-01AABI2chr2

204291992

-CHMP1Achr16

89713739

-


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Fusion Gene ORF analysis for ABI2-CHMP1A

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000261016ENST00000547614ABI2chr2

204291992

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000261017ENST00000547614ABI2chr2

204291992

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000261018ENST00000547614ABI2chr2

204291992

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000295851ENST00000547614ABI2chr2

204291992

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000422511ENST00000547614ABI2chr2

204291992

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000424558ENST00000547614ABI2chr2

204291992

-CHMP1Achr16

89713739

-
5CDS-5UTRENST00000430418ENST00000547614ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000261016ENST00000253475ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000261016ENST00000397901ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000261016ENST00000535997ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000261016ENST00000550102ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000261017ENST00000253475ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000261018ENST00000253475ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000295851ENST00000397901ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000295851ENST00000535997ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000295851ENST00000550102ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000422511ENST00000253475ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000422511ENST00000397901ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000422511ENST00000535997ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000422511ENST00000550102ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000424558ENST00000253475ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000424558ENST00000397901ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000424558ENST00000535997ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000424558ENST00000550102ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000430418ENST00000253475ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000430418ENST00000397901ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000430418ENST00000535997ABI2chr2

204291992

-CHMP1Achr16

89713739

-
Frame-shiftENST00000430418ENST00000550102ABI2chr2

204291992

-CHMP1Achr16

89713739

-
In-frameENST00000261017ENST00000397901ABI2chr2

204291992

-CHMP1Achr16

89713739

-
In-frameENST00000261017ENST00000535997ABI2chr2

204291992

-CHMP1Achr16

89713739

-
In-frameENST00000261017ENST00000550102ABI2chr2

204291992

-CHMP1Achr16

89713739

-
In-frameENST00000261018ENST00000397901ABI2chr2

204291992

-CHMP1Achr16

89713739

-
In-frameENST00000261018ENST00000535997ABI2chr2

204291992

-CHMP1Achr16

89713739

-
In-frameENST00000261018ENST00000550102ABI2chr2

204291992

-CHMP1Achr16

89713739

-
In-frameENST00000295851ENST00000253475ABI2chr2

204291992

-CHMP1Achr16

89713739

-
intron-3CDSENST00000430574ENST00000253475ABI2chr2

204291992

-CHMP1Achr16

89713739

-
intron-3CDSENST00000430574ENST00000397901ABI2chr2

204291992

-CHMP1Achr16

89713739

-
intron-3CDSENST00000430574ENST00000535997ABI2chr2

204291992

-CHMP1Achr16

89713739

-
intron-3CDSENST00000430574ENST00000550102ABI2chr2

204291992

-CHMP1Achr16

89713739

-
intron-5UTRENST00000430574ENST00000547614ABI2chr2

204291992

-CHMP1Achr16

89713739

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000295851ABI2chr2204291992-ENST00000253475CHMP1Achr1689713739-24083221161579913829656
ENST00000261017ABI2chr2204291992-ENST00000397901CHMP1Achr1689713739-836563912021569455
ENST00000261017ABI2chr2204291992-ENST00000535997CHMP1Achr1689713739-833363912021569455
ENST00000261017ABI2chr2204291992-ENST00000550102CHMP1Achr1689713739-690763912021569455
ENST00000261018ABI2chr2204291992-ENST00000397901CHMP1Achr1689713739-4118214417853278
ENST00000261018ABI2chr2204291992-ENST00000535997CHMP1Achr1689713739-4086214417853278
ENST00000261018ABI2chr2204291992-ENST00000550102CHMP1Achr1689713739-2660214417853278

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000295851ENST00000253475ABI2chr2204291992-CHMP1Achr1689713739-0.0004198570.9995802
ENST00000261017ENST00000397901ABI2chr2204291992-CHMP1Achr1689713739-0.000239610.99976045
ENST00000261017ENST00000535997ABI2chr2204291992-CHMP1Achr1689713739-0.0002404740.9997595
ENST00000261017ENST00000550102ABI2chr2204291992-CHMP1Achr1689713739-0.0001639130.9998361
ENST00000261018ENST00000397901ABI2chr2204291992-CHMP1Achr1689713739-0.0065494770.9934505
ENST00000261018ENST00000535997ABI2chr2204291992-CHMP1Achr1689713739-0.00667370.9933263
ENST00000261018ENST00000550102ABI2chr2204291992-CHMP1Achr1689713739-0.0040589610.99594104

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Fusion Genomic Features for ABI2-CHMP1A


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ABI2-CHMP1A


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr2:204291992/chr16:89713739)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ABI2

Q9NYB9

CHMP1A

Q9HD42

FUNCTION: Regulator of actin cytoskeleton dynamics underlying cell motility and adhesion. Functions as a component of the WAVE complex, which activates actin nucleating machinery Arp2/3 to drive lamellipodia formation (PubMed:21107423). Acts as regulator and substrate of nonreceptor tyrosine kinases ABL1 and ABL2 involved in processes linked to cell growth and differentiation. Positively regulates ABL1-mediated phosphorylation of ENAH, which is required for proper polymerization of nucleated actin filaments at the leading edge (PubMed:7590236, PubMed:8649853, PubMed:10498863). Contributes to the regulation of actin assembly at the tips of neuron projections. In particular, controls dendritic spine morphogenesis and may promote dendritic spine specification toward large mushroom-type spines known as repositories of memory in the brain (By similarity). In hippocampal neurons, may mediate actin-dependent BDNF-NTRK2 early endocytic trafficking that triggers dendrite outgrowth (By similarity). Participates in ocular lens morphogenesis, likely by regulating lamellipodia-driven adherens junction formation at the epithelial cell-secondary lens fiber interface (By similarity). Also required for nascent adherens junction assembly in epithelial cells (PubMed:15572692). {ECO:0000250|UniProtKB:P62484, ECO:0000269|PubMed:10498863, ECO:0000269|PubMed:15572692, ECO:0000269|PubMed:21107423, ECO:0000269|PubMed:7590236, ECO:0000269|PubMed:8649853}.FUNCTION: Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. Involved in cytokinesis. Involved in recruiting VPS4A and/or VPS4B to the midbody of dividing cells. May also be involved in chromosome condensation. Targets the Polycomb group (PcG) protein BMI1/PCGF4 to regions of condensed chromatin. May play a role in stable cell cycle progression and in PcG gene silencing. {ECO:0000269|PubMed:11559747, ECO:0000269|PubMed:11559748, ECO:0000269|PubMed:19129479, ECO:0000269|PubMed:23045692}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneCHMP1Achr2:204291992chr16:89713739ENST0000039790137102_12484197.0Coiled coilOntology_term=ECO:0000255
TgeneCHMP1Achr2:204291992chr16:89713739ENST0000039790137185_19584197.0MotifNote=MIT-interacting motif

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneABI2chr2:204291992chr16:89713739ENST00000261016-110172_4230402.0Compositional biasNote=Pro-rich
HgeneABI2chr2:204291992chr16:89713739ENST00000261017-110172_4230476.0Compositional biasNote=Pro-rich
HgeneABI2chr2:204291992chr16:89713739ENST00000424558-110172_4230508.0Compositional biasNote=Pro-rich
HgeneABI2chr2:204291992chr16:89713739ENST00000261016-110451_5100402.0DomainSH3
HgeneABI2chr2:204291992chr16:89713739ENST00000261016-11045_1070402.0Domaint-SNARE coiled-coil homology
HgeneABI2chr2:204291992chr16:89713739ENST00000261017-110451_5100476.0DomainSH3
HgeneABI2chr2:204291992chr16:89713739ENST00000261017-11045_1070476.0Domaint-SNARE coiled-coil homology
HgeneABI2chr2:204291992chr16:89713739ENST00000424558-110451_5100508.0DomainSH3
HgeneABI2chr2:204291992chr16:89713739ENST00000424558-11045_1070508.0Domaint-SNARE coiled-coil homology
TgeneCHMP1Achr2:204291992chr16:89713739ENST00000397901375_4784197.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for ABI2-CHMP1A


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>456_456_1_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261017_CHMP1A_chr16_89713739_ENST00000397901_length(transcript)=8365nt_BP=6391nt
GCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGT
CGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTG
CGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAAT
CCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGA
TAAGCAGAGAGCCCTAGAAGAAACCAAAGCCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGT
CCTGCAGATGCTGGATATCCAGGCATCCCAGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAACAGTTGATATTCATAAAGA
GAAAGTTGCAAGAAGAGAAATTGGTATTTTGACTACCAATAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACG
ACCAGTTCGTTATATTAGAAAACCTATTGACTATACAATTCTAGATGATATTGGACATGGAGTAAAGGTGAGTACCCAGAACATGAAGAT
GGGTGGGCTGCCGCGTACAACACCTCCAACTCAGAAGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGGCGGCACTCCCCCTA
TCGCACACTGGAGCCAGTGCGTCCTCCAGTGGTACCAAATGATTACGTACCTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCC
TGTGAGGACAGCTTCTGTGAATCAAAGAAATCGAACTTACAGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAG
TCGAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGGTCATCCTGTACA
GTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTTC
ACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGTATCTCTTGCTCCTCCTCCTCCCTCCATCCTACA
GGTAACTCCTCAGTTACCTTTAATGGGATTTGTGGCCAGAGTCCAAGAAAATATTTCAGATACACCACCTCCACCGCCACCTGTGGAAGA
ACCAGTCTTTGATGAGTCTCCCCCACCTCCTCCTCCTCCAGAAGATTACGAAGAGGAGGAAGCTGCTGTGGTTGAGTATAGTGATCCTTA
TGCTGAAGAGGACCCACCGTGGGCTCCACGTTCTTACTTGGAAAAGGGTTGGTATGAGGGAGTTATGAATGGAGTGACTGGGCTTTTTCC
TGGGAATTACGTTGAGTCTATCATGCATTATTCTGAGTAAAGCTCAGCAGGGCTGTGCTTGCCTCACAGGAATAGTCAGGTCTTCCCAGA
TTATCTGAAGGCCCTGGGGATTCCACTCCAGTAAAGTAGAATGAAGGATACAAATGATAAAAATTACACTTTTTTTTTTGGTTTATTCCC
CAGTATTAAAAACAAAGCAAGCTGAGTCTGAACAAATGGATCTTTCTGCCATCATTTGTACAATGCTGAGCTGTCTGGATTGAAATAAAA
TGACCATTTTTATGTATGTCAAAGGTATAACAGCATAACTGTGTAGCCAAAACAAAATCAGATTAAGACTGATTCAGAAAAATCTGGGAT
CTTTCTCAGGAATACTGTATACCCTTGGGATTTCTCCTCCTGCAGAATCTGTGGCATTGGATGTTCTTCATTGCCTGTGCTAAGGGGTTA
ACCTCATGGCCCAGTGGGTACCCTAGCCCCTTCTTTTCTTCCACTTGTATGAAGAGGAGGGAACCAACATTTAAATACCACACTTAACCA
TTTTTACAATTATTTCAGATGGCTTTTTTCCTCTGTGACACTGTAAATTCTGCATTCTCTCAGCACTTGAGTGCACCAAACGAGTGAATG
CTGAACTCACTTGCATCCCTTCATGTTTCTGTTTGTGGATTATAAGGATGATGAAATGTGAAAGTCTCCCAACACTCTGAGGGTGGTGAA
CGATTGCCACCCGTTTGATTTTAATGTGCTGCTGCATGAGACTGCATTGTTGCTAATGGCCAGTGTACCCAGATGTGAAGTGTGGTAGGC
TGGTTCATATGTGGAGGTGGGTGTGTGAAGCTAGACACGAAGGTCCCTAAGGTTCTGAAGAGACTTGAACTGTGGAAATGCTCTTAGCAG
GCATCCCGAACCCCTGCTTCGGTGCTGTTTTGAGGAGTAGGATCTTGGAGTTCAGACCAACTATGACTATCATTTCCTTCACTATCTAGA
AAAACGCTATTCTACTTTGGAAGAGAATAGTAGTTATTTTCAAGTCTCCTGACAGTCACTGGGAGTACAAGGTTTGCTAATGTGCTCTCT
GGACGTTATTAATGGCCAGTATTAGTTGCTGCTGTATTACTGACTCGCTTAGCTGTAGAAAGGGTAATACTCTCCTGATTTTGTATGATT
GGACTCTTAAGTAGCTGCTGTTAGTCAGAATTAAAACCCATCTCAGACTAAGAATATAATGAATAAGATTAATAGGCCAAAATATGTATC
TAATCACATTGATAAAAATTAATATAACTGACACAATAAAACACATTTCCCCCATCTGTACAATAAATACAGCTTCAAATTCAGTGGAGT
CTGTAGGGCAGATAACTTTAATCATCACTACTGTAGTCAGTATAAGAAATGCTGAAAAAAATCCAGGAGGGCTTGTCTCTTTGTGGGTGG
TCACTGTGATGTTGGGCCAGCTCCTGTTCAGGTCCAGAGCTGCTAACGTGGGTTCTACTCAGTCCCAGTGACTTGGCCAGAATAGAGCTT
TGCCAGGTAACTGCCCTGTGCTAGGTGAAAGGGGAAAAGCAGTAGCTGGATATATTTCAAATGAGGTTTTGAACAAGTTCAGAAAGTGGA
ACTTGATTGAAAAGTGAACAAGTGTAGTAGTGTGTGAGAAAATTCAGATGGTGTCGGATGCAGAAGTTAATATTCCACTTAATGTTATCT
GAGCATTAAAAATCATCAGCATTTAACTGAGACCCCACTATAGAGTTTCCTTATCAAGACTTTTTGGTTTTAAAGTTGTTTTTAATGCAT
TGCAAGTTACAATAGCTATTTTGCTTTTAGATTTTTCCCAGCACTTTGTATTTATTAGCTTTCATTAACTTGCCTCCAGTATACATTCCA
CTTCGTGCTTTTCTTAGGTCATTTCTACATCCCTTATTCCTTGTTTTCCTGCAGTGTAATGGCCCTGAATGTCCTCTGAGCCTTCAGCTC
CATTATGGACCCAAACTAGACTATACTTGGATAAGTTAAGCTCTTCTTCGTGTACTGGTCTATAATTAGAAAAACTGTTTTAAATTAGAT
GTTCCCATTATTTATTTAAACAGCTTTTTGCTGAGAAAGCTTAGTGGATTAATGAGGCAGAGGGTGTTTTGAAATCCAATAAATAGTTCC
CACAGGCTGGGTGTGGTGGCTTATGCCTGTAATCCCAGCACTTTCGGAGGCCGAGGTGGGTGGATCATGAGGTCAATAAATTGAGACCAT
CCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAACACAAAAATTAGCTGGGCGTGGTGGCGCACACCTGTAGTCCCAGCTACTTGGG
AGGCTGAGGCAGGAGAATCACTGGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGTGACAGAGC
GAGACTCCATCAAAAAAAAAAAAAAAAAGTTCCCACAGCTCACCACTACAGAAGCAGGGAAGACAACTATGCAGAAAACAGAGTTAGTGG
CGGTCAGCAGGAATGCAGCTGGTCTTTTGGACCCCTACGGGATGGGGGCAGTGCAGAAGACACTGGTGAAGTCCTTTATACTGAAGACCT
GTGGTTGGGAGCAGGGGTAGTCCATGGGTCTGCTGATTTTTTTTCCCTATTTAGTACTAATGTGTGTGTGATCTTTGTTTTACAAACAGT
ACCTTTTGGGTTTTCTGCATATTTTATAATTTTTGTACAGTTTTGAATTCTATAGATTGTCTTGGAAGGATACTGTGTGATGGGTCAGGC
ACACAGTAATTGGAGACTTTTAATGTATGTAATATTTCATAGATTGCATGCTATTAATCATCTGTGAGGGTAGTATTTTTTGTTTTATTG
TAAGTTTCCCTCTTTTTTTATAAATTAAAAGATGGTTGGTATTAGGAATTTCAAATGAATGCAGAAAATCTTACATGCTGTGTACTATTA
ATATTATAACAGACGATCCAAGTCCAAAATCTGACCAATAAAGCAACCATTTTATCAAGATAGAGGGATTCTAATGGGAGAGGGGATTCT
TCCCTCCTGAAGTTTGTGTGTCCAGTCCCCTTAAAAAAAATGAATAGTTGTCTTTTCTTGTCATATTAATACTCGAAAGTCCATGGTGGT
ATTAATGAAAGTACACTTTATTGTTGCCTTTGAACTTACGGCCAAGGCAATAAATCAGAAACAAAAATAGTGCCAATGTGTCAAAATCGA
CATCTGAGAGATTCAGCCTCCCATTTGGAATAAATATGAATCTTCTAAGCTATCTTGTTTAATATTTTCCATCATTTAGCTACTTCCTAT
CTCCCTCAGAGGCGCCTGCTGTTCCCATTTTAGAGTTGACAGTGGCCTGCTAATTTTGCTATGTTCCTAAAAGTTACTGGGTGTGAGACA
TTTTCATCCCCTCCTTTTTCCTACTGCTGGTGTTTATTATCCAGCTAGACAATATTTTATGCATATTTACCGTGATGTCTGGACCGTACC
TGTGCTCCTTGGCAGTTTATGTTGAAGATAACTAAAGATTTTTCTCTTTGGGAGGCATCAAAATGATGGTAGTTTGCTTTTATCTTTTTA
TGTTCATTTTCTTTTAGTAGGTGACCTTTCTGCATTAAGAACTGTTTTTATCTTTTACTACCTTTTCTTTTCTCCTTTGTGGAGACAGCA
TGACATGTCCTGAAGGTCACCTTTGCCTTTGAAAAAGGTTTGATGGAGGAATTCACAGGTGACTGACAAGTCTTTGAAAAGAATGGGATC
TGCTCACTTCTGGTCTTTTTGGCCGGGAACTCCTGATTGGTGTTAAGGTGGTAATTTCCCCCATATAAGATTTAGAATCACTGAGTTTGA
GCTAGATGAAATTTTTAAAATTTCTGGTTGTCTCATTAGACTGATGAGGTGAGTTTTCTTCTTCATATGAACAGCTAGTTAATAACAGCA
GAGTTCTCACTCAGTGCTCAGTACTTAATTTTCCACTGCACCACAACTGTCTTAACTAAATGTGCTGTATTTTTCTTTAAAAGTTAAGAG
TTCTATTTGGTGTTTTCAGGAATATACGTGAAAAGACATGCCATGTTTTGGTAAATACCATCAGAGTTGTGTAAAGGCGTGTACTAAGTG
CAATCTTAATTTGTGGAAATAATCTTCATTTACCCCTCCTAAAACTACACTCAGTATAAACACTTTCCCATAAGGTGTGTGCAGTAAAAA
TGTTATATTACTCCAACACTGGCAGGAGCACAGCACAGCAGCCTTATTGGAGAGAGCCTTATAAAAGTGATTAAATGGAGGCATTGAGCT
CATTACCTTTAAGTTTACTTTGTGCTGACCTTTGTTCCTGTTTTGAGAATCTCATATAATTATTAAAAAAAAAAAACAATTAAAACGAAA
CGGCGGGGCCTAGCTGTGTATAAATGATCCTTGCTGAATATCTTAAGGTTTTTTGTAAGAAAAAAGAAAAACCAACAAAAAAAGCTTATT
TTCACATTAAAATGAAACCTCTTTTGCAACTTAAGAATTCTATGGAAAAGCAGTTTTTATCATATTTTGTGTCCATGCACCATTTTTCTT
AAAATGGCTTACAAAAAAGAATGTAAACAATTTGTGATCTGGCCAGTTGTACTTTTAGCTCCCAGAGGGAGAGTTGGTGGTATTATGAGT
TGAGTAAAAACCATCCAGGGGAACTTGAGGGAGCAGTCTGTTGCCAGTAATGTTCCTTGTGTGCCATTAAACCACCTCCAGATGAGTGGA
GGAACATCACTTTTTAATTTTTTAATTGTATTTGGAATTGTTGCCGTGTACTAAGAACTTGACCTAAATAAAATCCCACAAAGTATATTC
AGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAG
GTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGA
GCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGC
CGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCA
CCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCA
GCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGT
TGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCA
CTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCC
TGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTG
GGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGC
CCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTC
ACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGT
GCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGT
TCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCC
CGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGG
GGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTG
GGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAA
AGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAG
CCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCA
GAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGA
GAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTG

>456_456_1_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261017_CHMP1A_chr16_89713739_ENST00000397901_length(amino acids)=455AA_BP=
MYEEEEEEDVKMAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQ
ASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTT
PPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSG
SVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPL
MGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKGWYEGVMNGVTGLFPGNYVESI

--------------------------------------------------------------
>456_456_2_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261017_CHMP1A_chr16_89713739_ENST00000535997_length(transcript)=8333nt_BP=6391nt
GCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGT
CGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTG
CGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAAT
CCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGA
TAAGCAGAGAGCCCTAGAAGAAACCAAAGCCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGT
CCTGCAGATGCTGGATATCCAGGCATCCCAGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAACAGTTGATATTCATAAAGA
GAAAGTTGCAAGAAGAGAAATTGGTATTTTGACTACCAATAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACG
ACCAGTTCGTTATATTAGAAAACCTATTGACTATACAATTCTAGATGATATTGGACATGGAGTAAAGGTGAGTACCCAGAACATGAAGAT
GGGTGGGCTGCCGCGTACAACACCTCCAACTCAGAAGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGGCGGCACTCCCCCTA
TCGCACACTGGAGCCAGTGCGTCCTCCAGTGGTACCAAATGATTACGTACCTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCC
TGTGAGGACAGCTTCTGTGAATCAAAGAAATCGAACTTACAGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAG
TCGAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGGTCATCCTGTACA
GTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTTC
ACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGTATCTCTTGCTCCTCCTCCTCCCTCCATCCTACA
GGTAACTCCTCAGTTACCTTTAATGGGATTTGTGGCCAGAGTCCAAGAAAATATTTCAGATACACCACCTCCACCGCCACCTGTGGAAGA
ACCAGTCTTTGATGAGTCTCCCCCACCTCCTCCTCCTCCAGAAGATTACGAAGAGGAGGAAGCTGCTGTGGTTGAGTATAGTGATCCTTA
TGCTGAAGAGGACCCACCGTGGGCTCCACGTTCTTACTTGGAAAAGGGTTGGTATGAGGGAGTTATGAATGGAGTGACTGGGCTTTTTCC
TGGGAATTACGTTGAGTCTATCATGCATTATTCTGAGTAAAGCTCAGCAGGGCTGTGCTTGCCTCACAGGAATAGTCAGGTCTTCCCAGA
TTATCTGAAGGCCCTGGGGATTCCACTCCAGTAAAGTAGAATGAAGGATACAAATGATAAAAATTACACTTTTTTTTTTGGTTTATTCCC
CAGTATTAAAAACAAAGCAAGCTGAGTCTGAACAAATGGATCTTTCTGCCATCATTTGTACAATGCTGAGCTGTCTGGATTGAAATAAAA
TGACCATTTTTATGTATGTCAAAGGTATAACAGCATAACTGTGTAGCCAAAACAAAATCAGATTAAGACTGATTCAGAAAAATCTGGGAT
CTTTCTCAGGAATACTGTATACCCTTGGGATTTCTCCTCCTGCAGAATCTGTGGCATTGGATGTTCTTCATTGCCTGTGCTAAGGGGTTA
ACCTCATGGCCCAGTGGGTACCCTAGCCCCTTCTTTTCTTCCACTTGTATGAAGAGGAGGGAACCAACATTTAAATACCACACTTAACCA
TTTTTACAATTATTTCAGATGGCTTTTTTCCTCTGTGACACTGTAAATTCTGCATTCTCTCAGCACTTGAGTGCACCAAACGAGTGAATG
CTGAACTCACTTGCATCCCTTCATGTTTCTGTTTGTGGATTATAAGGATGATGAAATGTGAAAGTCTCCCAACACTCTGAGGGTGGTGAA
CGATTGCCACCCGTTTGATTTTAATGTGCTGCTGCATGAGACTGCATTGTTGCTAATGGCCAGTGTACCCAGATGTGAAGTGTGGTAGGC
TGGTTCATATGTGGAGGTGGGTGTGTGAAGCTAGACACGAAGGTCCCTAAGGTTCTGAAGAGACTTGAACTGTGGAAATGCTCTTAGCAG
GCATCCCGAACCCCTGCTTCGGTGCTGTTTTGAGGAGTAGGATCTTGGAGTTCAGACCAACTATGACTATCATTTCCTTCACTATCTAGA
AAAACGCTATTCTACTTTGGAAGAGAATAGTAGTTATTTTCAAGTCTCCTGACAGTCACTGGGAGTACAAGGTTTGCTAATGTGCTCTCT
GGACGTTATTAATGGCCAGTATTAGTTGCTGCTGTATTACTGACTCGCTTAGCTGTAGAAAGGGTAATACTCTCCTGATTTTGTATGATT
GGACTCTTAAGTAGCTGCTGTTAGTCAGAATTAAAACCCATCTCAGACTAAGAATATAATGAATAAGATTAATAGGCCAAAATATGTATC
TAATCACATTGATAAAAATTAATATAACTGACACAATAAAACACATTTCCCCCATCTGTACAATAAATACAGCTTCAAATTCAGTGGAGT
CTGTAGGGCAGATAACTTTAATCATCACTACTGTAGTCAGTATAAGAAATGCTGAAAAAAATCCAGGAGGGCTTGTCTCTTTGTGGGTGG
TCACTGTGATGTTGGGCCAGCTCCTGTTCAGGTCCAGAGCTGCTAACGTGGGTTCTACTCAGTCCCAGTGACTTGGCCAGAATAGAGCTT
TGCCAGGTAACTGCCCTGTGCTAGGTGAAAGGGGAAAAGCAGTAGCTGGATATATTTCAAATGAGGTTTTGAACAAGTTCAGAAAGTGGA
ACTTGATTGAAAAGTGAACAAGTGTAGTAGTGTGTGAGAAAATTCAGATGGTGTCGGATGCAGAAGTTAATATTCCACTTAATGTTATCT
GAGCATTAAAAATCATCAGCATTTAACTGAGACCCCACTATAGAGTTTCCTTATCAAGACTTTTTGGTTTTAAAGTTGTTTTTAATGCAT
TGCAAGTTACAATAGCTATTTTGCTTTTAGATTTTTCCCAGCACTTTGTATTTATTAGCTTTCATTAACTTGCCTCCAGTATACATTCCA
CTTCGTGCTTTTCTTAGGTCATTTCTACATCCCTTATTCCTTGTTTTCCTGCAGTGTAATGGCCCTGAATGTCCTCTGAGCCTTCAGCTC
CATTATGGACCCAAACTAGACTATACTTGGATAAGTTAAGCTCTTCTTCGTGTACTGGTCTATAATTAGAAAAACTGTTTTAAATTAGAT
GTTCCCATTATTTATTTAAACAGCTTTTTGCTGAGAAAGCTTAGTGGATTAATGAGGCAGAGGGTGTTTTGAAATCCAATAAATAGTTCC
CACAGGCTGGGTGTGGTGGCTTATGCCTGTAATCCCAGCACTTTCGGAGGCCGAGGTGGGTGGATCATGAGGTCAATAAATTGAGACCAT
CCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAACACAAAAATTAGCTGGGCGTGGTGGCGCACACCTGTAGTCCCAGCTACTTGGG
AGGCTGAGGCAGGAGAATCACTGGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGTGACAGAGC
GAGACTCCATCAAAAAAAAAAAAAAAAAGTTCCCACAGCTCACCACTACAGAAGCAGGGAAGACAACTATGCAGAAAACAGAGTTAGTGG
CGGTCAGCAGGAATGCAGCTGGTCTTTTGGACCCCTACGGGATGGGGGCAGTGCAGAAGACACTGGTGAAGTCCTTTATACTGAAGACCT
GTGGTTGGGAGCAGGGGTAGTCCATGGGTCTGCTGATTTTTTTTCCCTATTTAGTACTAATGTGTGTGTGATCTTTGTTTTACAAACAGT
ACCTTTTGGGTTTTCTGCATATTTTATAATTTTTGTACAGTTTTGAATTCTATAGATTGTCTTGGAAGGATACTGTGTGATGGGTCAGGC
ACACAGTAATTGGAGACTTTTAATGTATGTAATATTTCATAGATTGCATGCTATTAATCATCTGTGAGGGTAGTATTTTTTGTTTTATTG
TAAGTTTCCCTCTTTTTTTATAAATTAAAAGATGGTTGGTATTAGGAATTTCAAATGAATGCAGAAAATCTTACATGCTGTGTACTATTA
ATATTATAACAGACGATCCAAGTCCAAAATCTGACCAATAAAGCAACCATTTTATCAAGATAGAGGGATTCTAATGGGAGAGGGGATTCT
TCCCTCCTGAAGTTTGTGTGTCCAGTCCCCTTAAAAAAAATGAATAGTTGTCTTTTCTTGTCATATTAATACTCGAAAGTCCATGGTGGT
ATTAATGAAAGTACACTTTATTGTTGCCTTTGAACTTACGGCCAAGGCAATAAATCAGAAACAAAAATAGTGCCAATGTGTCAAAATCGA
CATCTGAGAGATTCAGCCTCCCATTTGGAATAAATATGAATCTTCTAAGCTATCTTGTTTAATATTTTCCATCATTTAGCTACTTCCTAT
CTCCCTCAGAGGCGCCTGCTGTTCCCATTTTAGAGTTGACAGTGGCCTGCTAATTTTGCTATGTTCCTAAAAGTTACTGGGTGTGAGACA
TTTTCATCCCCTCCTTTTTCCTACTGCTGGTGTTTATTATCCAGCTAGACAATATTTTATGCATATTTACCGTGATGTCTGGACCGTACC
TGTGCTCCTTGGCAGTTTATGTTGAAGATAACTAAAGATTTTTCTCTTTGGGAGGCATCAAAATGATGGTAGTTTGCTTTTATCTTTTTA
TGTTCATTTTCTTTTAGTAGGTGACCTTTCTGCATTAAGAACTGTTTTTATCTTTTACTACCTTTTCTTTTCTCCTTTGTGGAGACAGCA
TGACATGTCCTGAAGGTCACCTTTGCCTTTGAAAAAGGTTTGATGGAGGAATTCACAGGTGACTGACAAGTCTTTGAAAAGAATGGGATC
TGCTCACTTCTGGTCTTTTTGGCCGGGAACTCCTGATTGGTGTTAAGGTGGTAATTTCCCCCATATAAGATTTAGAATCACTGAGTTTGA
GCTAGATGAAATTTTTAAAATTTCTGGTTGTCTCATTAGACTGATGAGGTGAGTTTTCTTCTTCATATGAACAGCTAGTTAATAACAGCA
GAGTTCTCACTCAGTGCTCAGTACTTAATTTTCCACTGCACCACAACTGTCTTAACTAAATGTGCTGTATTTTTCTTTAAAAGTTAAGAG
TTCTATTTGGTGTTTTCAGGAATATACGTGAAAAGACATGCCATGTTTTGGTAAATACCATCAGAGTTGTGTAAAGGCGTGTACTAAGTG
CAATCTTAATTTGTGGAAATAATCTTCATTTACCCCTCCTAAAACTACACTCAGTATAAACACTTTCCCATAAGGTGTGTGCAGTAAAAA
TGTTATATTACTCCAACACTGGCAGGAGCACAGCACAGCAGCCTTATTGGAGAGAGCCTTATAAAAGTGATTAAATGGAGGCATTGAGCT
CATTACCTTTAAGTTTACTTTGTGCTGACCTTTGTTCCTGTTTTGAGAATCTCATATAATTATTAAAAAAAAAAAACAATTAAAACGAAA
CGGCGGGGCCTAGCTGTGTATAAATGATCCTTGCTGAATATCTTAAGGTTTTTTGTAAGAAAAAAGAAAAACCAACAAAAAAAGCTTATT
TTCACATTAAAATGAAACCTCTTTTGCAACTTAAGAATTCTATGGAAAAGCAGTTTTTATCATATTTTGTGTCCATGCACCATTTTTCTT
AAAATGGCTTACAAAAAAGAATGTAAACAATTTGTGATCTGGCCAGTTGTACTTTTAGCTCCCAGAGGGAGAGTTGGTGGTATTATGAGT
TGAGTAAAAACCATCCAGGGGAACTTGAGGGAGCAGTCTGTTGCCAGTAATGTTCCTTGTGTGCCATTAAACCACCTCCAGATGAGTGGA
GGAACATCACTTTTTAATTTTTTAATTGTATTTGGAATTGTTGCCGTGTACTAAGAACTTGACCTAAATAAAATCCCACAAAGTATATTC
AGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAG
GTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGA
GCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGC
CGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCA
CCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCA
GCCACTCTGCGTCTCTCACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGT
TGAGTTTCTGCAAATTTCTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCA
CTGTGGGGGCCTTCAGACTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCC
TGAGGCCTCTCCGCACCACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTG
GGGGATGTCAGGTGCCACCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGC
CCCTACCAGCTGGCTGAGCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTC
ACTCAGATCCACATTCAAGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGT
GCTGTTTGTCTCCTCGACAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGT
TCTCCCGGAGGACCTTTCCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCC
CGACCACACCCCAATGCCTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGG
GGCTGCTGTGAGGAAAACCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTG
GGCACAGCCTGCTGTCTTTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAA
AGGCAGGTGGTGGGCGGCTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAG
CCCATGCTGAGGCTGCAGTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCA
GAACTTGGGAGCCCCCAGGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGA
GAACGTCCTTCTGTCCATCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTG

>456_456_2_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261017_CHMP1A_chr16_89713739_ENST00000535997_length(amino acids)=455AA_BP=
MYEEEEEEDVKMAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQ
ASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTT
PPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSG
SVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPL
MGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKGWYEGVMNGVTGLFPGNYVESI

--------------------------------------------------------------
>456_456_3_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261017_CHMP1A_chr16_89713739_ENST00000550102_length(transcript)=6907nt_BP=6391nt
GCGCGTGCGCGCGCCCGGCCGGCCGTCGCCGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGT
CGCGCGCTGGGGCTGTTTCTCGCTCCTTCCGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTG
CGGCCGCCGCTCCCTCTGCGACCTGTATGAGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAAT
CCCGGGGGGCCGCCGGGCCCTCTTCGACAGCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGA
TAAGCAGAGAGCCCTAGAAGAAACCAAAGCCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGT
CCTGCAGATGCTGGATATCCAGGCATCCCAGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAACAGTTGATATTCATAAAGA
GAAAGTTGCAAGAAGAGAAATTGGTATTTTGACTACCAATAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACG
ACCAGTTCGTTATATTAGAAAACCTATTGACTATACAATTCTAGATGATATTGGACATGGAGTAAAGGTGAGTACCCAGAACATGAAGAT
GGGTGGGCTGCCGCGTACAACACCTCCAACTCAGAAGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGGCGGCACTCCCCCTA
TCGCACACTGGAGCCAGTGCGTCCTCCAGTGGTACCAAATGATTACGTACCTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCC
TGTGAGGACAGCTTCTGTGAATCAAAGAAATCGAACTTACAGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAG
TCGAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGGTCATCCTGTACA
GTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTTC
ACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGTATCTCTTGCTCCTCCTCCTCCCTCCATCCTACA
GGTAACTCCTCAGTTACCTTTAATGGGATTTGTGGCCAGAGTCCAAGAAAATATTTCAGATACACCACCTCCACCGCCACCTGTGGAAGA
ACCAGTCTTTGATGAGTCTCCCCCACCTCCTCCTCCTCCAGAAGATTACGAAGAGGAGGAAGCTGCTGTGGTTGAGTATAGTGATCCTTA
TGCTGAAGAGGACCCACCGTGGGCTCCACGTTCTTACTTGGAAAAGGGTTGGTATGAGGGAGTTATGAATGGAGTGACTGGGCTTTTTCC
TGGGAATTACGTTGAGTCTATCATGCATTATTCTGAGTAAAGCTCAGCAGGGCTGTGCTTGCCTCACAGGAATAGTCAGGTCTTCCCAGA
TTATCTGAAGGCCCTGGGGATTCCACTCCAGTAAAGTAGAATGAAGGATACAAATGATAAAAATTACACTTTTTTTTTTGGTTTATTCCC
CAGTATTAAAAACAAAGCAAGCTGAGTCTGAACAAATGGATCTTTCTGCCATCATTTGTACAATGCTGAGCTGTCTGGATTGAAATAAAA
TGACCATTTTTATGTATGTCAAAGGTATAACAGCATAACTGTGTAGCCAAAACAAAATCAGATTAAGACTGATTCAGAAAAATCTGGGAT
CTTTCTCAGGAATACTGTATACCCTTGGGATTTCTCCTCCTGCAGAATCTGTGGCATTGGATGTTCTTCATTGCCTGTGCTAAGGGGTTA
ACCTCATGGCCCAGTGGGTACCCTAGCCCCTTCTTTTCTTCCACTTGTATGAAGAGGAGGGAACCAACATTTAAATACCACACTTAACCA
TTTTTACAATTATTTCAGATGGCTTTTTTCCTCTGTGACACTGTAAATTCTGCATTCTCTCAGCACTTGAGTGCACCAAACGAGTGAATG
CTGAACTCACTTGCATCCCTTCATGTTTCTGTTTGTGGATTATAAGGATGATGAAATGTGAAAGTCTCCCAACACTCTGAGGGTGGTGAA
CGATTGCCACCCGTTTGATTTTAATGTGCTGCTGCATGAGACTGCATTGTTGCTAATGGCCAGTGTACCCAGATGTGAAGTGTGGTAGGC
TGGTTCATATGTGGAGGTGGGTGTGTGAAGCTAGACACGAAGGTCCCTAAGGTTCTGAAGAGACTTGAACTGTGGAAATGCTCTTAGCAG
GCATCCCGAACCCCTGCTTCGGTGCTGTTTTGAGGAGTAGGATCTTGGAGTTCAGACCAACTATGACTATCATTTCCTTCACTATCTAGA
AAAACGCTATTCTACTTTGGAAGAGAATAGTAGTTATTTTCAAGTCTCCTGACAGTCACTGGGAGTACAAGGTTTGCTAATGTGCTCTCT
GGACGTTATTAATGGCCAGTATTAGTTGCTGCTGTATTACTGACTCGCTTAGCTGTAGAAAGGGTAATACTCTCCTGATTTTGTATGATT
GGACTCTTAAGTAGCTGCTGTTAGTCAGAATTAAAACCCATCTCAGACTAAGAATATAATGAATAAGATTAATAGGCCAAAATATGTATC
TAATCACATTGATAAAAATTAATATAACTGACACAATAAAACACATTTCCCCCATCTGTACAATAAATACAGCTTCAAATTCAGTGGAGT
CTGTAGGGCAGATAACTTTAATCATCACTACTGTAGTCAGTATAAGAAATGCTGAAAAAAATCCAGGAGGGCTTGTCTCTTTGTGGGTGG
TCACTGTGATGTTGGGCCAGCTCCTGTTCAGGTCCAGAGCTGCTAACGTGGGTTCTACTCAGTCCCAGTGACTTGGCCAGAATAGAGCTT
TGCCAGGTAACTGCCCTGTGCTAGGTGAAAGGGGAAAAGCAGTAGCTGGATATATTTCAAATGAGGTTTTGAACAAGTTCAGAAAGTGGA
ACTTGATTGAAAAGTGAACAAGTGTAGTAGTGTGTGAGAAAATTCAGATGGTGTCGGATGCAGAAGTTAATATTCCACTTAATGTTATCT
GAGCATTAAAAATCATCAGCATTTAACTGAGACCCCACTATAGAGTTTCCTTATCAAGACTTTTTGGTTTTAAAGTTGTTTTTAATGCAT
TGCAAGTTACAATAGCTATTTTGCTTTTAGATTTTTCCCAGCACTTTGTATTTATTAGCTTTCATTAACTTGCCTCCAGTATACATTCCA
CTTCGTGCTTTTCTTAGGTCATTTCTACATCCCTTATTCCTTGTTTTCCTGCAGTGTAATGGCCCTGAATGTCCTCTGAGCCTTCAGCTC
CATTATGGACCCAAACTAGACTATACTTGGATAAGTTAAGCTCTTCTTCGTGTACTGGTCTATAATTAGAAAAACTGTTTTAAATTAGAT
GTTCCCATTATTTATTTAAACAGCTTTTTGCTGAGAAAGCTTAGTGGATTAATGAGGCAGAGGGTGTTTTGAAATCCAATAAATAGTTCC
CACAGGCTGGGTGTGGTGGCTTATGCCTGTAATCCCAGCACTTTCGGAGGCCGAGGTGGGTGGATCATGAGGTCAATAAATTGAGACCAT
CCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAACACAAAAATTAGCTGGGCGTGGTGGCGCACACCTGTAGTCCCAGCTACTTGGG
AGGCTGAGGCAGGAGAATCACTGGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGTGACAGAGC
GAGACTCCATCAAAAAAAAAAAAAAAAAGTTCCCACAGCTCACCACTACAGAAGCAGGGAAGACAACTATGCAGAAAACAGAGTTAGTGG
CGGTCAGCAGGAATGCAGCTGGTCTTTTGGACCCCTACGGGATGGGGGCAGTGCAGAAGACACTGGTGAAGTCCTTTATACTGAAGACCT
GTGGTTGGGAGCAGGGGTAGTCCATGGGTCTGCTGATTTTTTTTCCCTATTTAGTACTAATGTGTGTGTGATCTTTGTTTTACAAACAGT
ACCTTTTGGGTTTTCTGCATATTTTATAATTTTTGTACAGTTTTGAATTCTATAGATTGTCTTGGAAGGATACTGTGTGATGGGTCAGGC
ACACAGTAATTGGAGACTTTTAATGTATGTAATATTTCATAGATTGCATGCTATTAATCATCTGTGAGGGTAGTATTTTTTGTTTTATTG
TAAGTTTCCCTCTTTTTTTATAAATTAAAAGATGGTTGGTATTAGGAATTTCAAATGAATGCAGAAAATCTTACATGCTGTGTACTATTA
ATATTATAACAGACGATCCAAGTCCAAAATCTGACCAATAAAGCAACCATTTTATCAAGATAGAGGGATTCTAATGGGAGAGGGGATTCT
TCCCTCCTGAAGTTTGTGTGTCCAGTCCCCTTAAAAAAAATGAATAGTTGTCTTTTCTTGTCATATTAATACTCGAAAGTCCATGGTGGT
ATTAATGAAAGTACACTTTATTGTTGCCTTTGAACTTACGGCCAAGGCAATAAATCAGAAACAAAAATAGTGCCAATGTGTCAAAATCGA
CATCTGAGAGATTCAGCCTCCCATTTGGAATAAATATGAATCTTCTAAGCTATCTTGTTTAATATTTTCCATCATTTAGCTACTTCCTAT
CTCCCTCAGAGGCGCCTGCTGTTCCCATTTTAGAGTTGACAGTGGCCTGCTAATTTTGCTATGTTCCTAAAAGTTACTGGGTGTGAGACA
TTTTCATCCCCTCCTTTTTCCTACTGCTGGTGTTTATTATCCAGCTAGACAATATTTTATGCATATTTACCGTGATGTCTGGACCGTACC
TGTGCTCCTTGGCAGTTTATGTTGAAGATAACTAAAGATTTTTCTCTTTGGGAGGCATCAAAATGATGGTAGTTTGCTTTTATCTTTTTA
TGTTCATTTTCTTTTAGTAGGTGACCTTTCTGCATTAAGAACTGTTTTTATCTTTTACTACCTTTTCTTTTCTCCTTTGTGGAGACAGCA
TGACATGTCCTGAAGGTCACCTTTGCCTTTGAAAAAGGTTTGATGGAGGAATTCACAGGTGACTGACAAGTCTTTGAAAAGAATGGGATC
TGCTCACTTCTGGTCTTTTTGGCCGGGAACTCCTGATTGGTGTTAAGGTGGTAATTTCCCCCATATAAGATTTAGAATCACTGAGTTTGA
GCTAGATGAAATTTTTAAAATTTCTGGTTGTCTCATTAGACTGATGAGGTGAGTTTTCTTCTTCATATGAACAGCTAGTTAATAACAGCA
GAGTTCTCACTCAGTGCTCAGTACTTAATTTTCCACTGCACCACAACTGTCTTAACTAAATGTGCTGTATTTTTCTTTAAAAGTTAAGAG
TTCTATTTGGTGTTTTCAGGAATATACGTGAAAAGACATGCCATGTTTTGGTAAATACCATCAGAGTTGTGTAAAGGCGTGTACTAAGTG
CAATCTTAATTTGTGGAAATAATCTTCATTTACCCCTCCTAAAACTACACTCAGTATAAACACTTTCCCATAAGGTGTGTGCAGTAAAAA
TGTTATATTACTCCAACACTGGCAGGAGCACAGCACAGCAGCCTTATTGGAGAGAGCCTTATAAAAGTGATTAAATGGAGGCATTGAGCT
CATTACCTTTAAGTTTACTTTGTGCTGACCTTTGTTCCTGTTTTGAGAATCTCATATAATTATTAAAAAAAAAAAACAATTAAAACGAAA
CGGCGGGGCCTAGCTGTGTATAAATGATCCTTGCTGAATATCTTAAGGTTTTTTGTAAGAAAAAAGAAAAACCAACAAAAAAAGCTTATT
TTCACATTAAAATGAAACCTCTTTTGCAACTTAAGAATTCTATGGAAAAGCAGTTTTTATCATATTTTGTGTCCATGCACCATTTTTCTT
AAAATGGCTTACAAAAAAGAATGTAAACAATTTGTGATCTGGCCAGTTGTACTTTTAGCTCCCAGAGGGAGAGTTGGTGGTATTATGAGT
TGAGTAAAAACCATCCAGGGGAACTTGAGGGAGCAGTCTGTTGCCAGTAATGTTCCTTGTGTGCCATTAAACCACCTCCAGATGAGTGGA
GGAACATCACTTTTTAATTTTTTAATTGTATTTGGAATTGTTGCCGTGTACTAAGAACTTGACCTAAATAAAATCCCACAAAGTATATTC
AGTGACCAAGAATATGGCCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAG
GTTCGAGCAGCAGGTGCAGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGA
GCAGGTGGACAGCCTCATCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGC
CGTGGGCGAGAGCTCTGTGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCA
CCGCCTCTGCCCCGTGATGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCA

>456_456_3_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261017_CHMP1A_chr16_89713739_ENST00000550102_length(amino acids)=455AA_BP=
MYEEEEEEDVKMAELQMLLEEEIPGGRRALFDSYTNLERVADYCENNYIQSADKQRALEETKAYTTQSLASVAYLINTLANNVLQMLDIQ
ASQLRRMESSINHISQTVDIHKEKVARREIGILTTNKNTSRTHKIIAPANLERPVRYIRKPIDYTILDDIGHGVKVSTQNMKMGGLPRTT
PPTQKPPSPPMSGKGTLGRHSPYRTLEPVRPPVVPNDYVPSPTRNMAPSQQSPVRTASVNQRNRTYSSSGSSGGSHPSSRSSSRENSGSG
SVGVPIAVPTPSPPSVFPGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQNQMNGGPFYSQNPVSLAPPPPSILQVTPQLPL
MGFVARVQENISDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKGWYEGVMNGVTGLFPGNYVESI

--------------------------------------------------------------
>456_456_4_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261018_CHMP1A_chr16_89713739_ENST00000397901_length(transcript)=4118nt_BP=2144nt
ATTTATGCATTAAGTGGTTGCTTAGATTTAAGGTGAGTACCCAGAACATGAAGATGGGTGGGCTGCCGCGTACAACACCTCCAACTCAGA
AGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAGTC
GAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGCCCCTGCTGGCTCTG
CTGGCACTCCTCCCCTTCCTGCTACTTCTGCATCTGCCCCTGCTCCTCTTGTTCCTGCTACTGTCCCTTCCTCCACTGCCCCAGACGCTG
CTGCTGGGGGTGCCCAGACCCTTGCTGATGGCTTCACTTCTCCAACTCCCCCTGTTGTTTCTTCCACTCCCCCTACAGGTCATCCTGTAC
AGTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTT
CACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGTTTCAGATACACCACCTCCACCGCCACCTGTGG
AAGAACCAGTCTTTGATGAGTCTCCCCCACCTCCTCCTCCTCCAGAAGATTACGAAGAGGAGGAAGCTGCTGTGGTTGAGTATAGTGATC
CTTATGCTGAAGAGGACCCACCGTGGGCTCCACGTTCTTACTTGGAAAAGGGTTGGTATGAGGGAGTTATGAATGGAGTGACTGGGCTTT
TTCCTGGGAATTACGTTGAGTCTATCATGCATTATTCTGAGTAAAGCTCAGCAGGGCTGTGCTTGCCTCACAGGAATAGTCAGGTCTTCC
CAGATTATCTGAAGGCCCTGGGGATTCCACTCCAGTAAAGTAGAATGAAGGATACAAATGATAAAAATTACACTTTTTTTTTTGGTTTAT
TCCCCAGTATTAAAAACAAAGCAAGCTGAGTCTGAACAAATGGATCTTTCTGCCATCATTTGTACAATGCTGAGCTGTCTGGATTGAAAT
AAAATGACCATTTTTATGTATGTCAAAGGTATAACAGCATAACTGTGTAGCCAAAACAAAATCAGATTAAGACTGATTCAGAAAAATCTG
GGATCTTTCTCAGGAATACTGTATACCCTTGGGATTTCTCCTCCTGCAGAATCTGTGGCATTGGATGTTCTTCATTGCCTGTGCTAAGGG
GTTAACCTCATGGCCCAGTGGGTACCCTAGCCCCTTCTTTTCTTCCACTTGTATGAAGAGGAGGGAACCAACATTTAAATACCACACTTA
ACCATTTTTACAATTATTTCAGATGGCTTTTTTCCTCTGTGACACTGTAAATTCTGCATTCTCTCAGCACTTGAGTGCACCAAACGAGTG
AATGCTGAACTCACTTGCATCCCTTCATGTTTCTGTTTGTGGATTATAAGGATGATGAAATGTGAAAGTCTCCCAACACTCTGAGGGTGG
TGAACGATTGCCACCCGTTTGATTTTAATGTGCTGCTGCATGAGACTGCATTGTTGCTAATGGCCAGTGTACCCAGATGTGAAGTGTGGT
AGGCTGGTTCATATGTGGAGGTGGGTGTGTGAAGCTAGACACGAAGGTCCCTAAGGTTCTGAAGAGACTTGAACTGTGGAAATGCTCTTA
GCAGGCATCCCGAACCCCTGCTTCGGTGCTGTTTTGAGGAGTAGGATCTTGGAGTTCAGACCAACTATGACTATCATTTCCTTCACTATC
TAGAAAAACGCTATTCTACTTTGGAAGAGAATAGTAGTTATTTTCAAGTCTCCTGACAGTCACTGGGAGTACAAGGTTTGCTAATGTGCT
CTCTGGACGTTATTAATGGCCAGTATTAGTTGCTGCTGTATTACTGACTCGCTTAGCTGTAGAAAGGGTAATACTCTCCTGATTTTGTAT
GATTGGACTCTTAAGTAGCTGCTGTTAGTCAGAATTAAAACCCATCTCAGACTAAGAATATAATGAATAAGATTAATAGGCCAAAATATG
TATCTAATCACATTGATAAAAATTAATATAACTGACACAATAAAACACATTTCCCCCATCTGTACAATAAATACGTGACCAAGAATATGG
CCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGC
AGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCA
TCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTG
TGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGA
TGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTC
ACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTT
CTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGA
CTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACC
ACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCA
CCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGA
GCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCA
AGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGA
CAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTT
CCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGC
CTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAA
CCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCT
TTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGG
CTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCA
GTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCA
GGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCA
TCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAG

>456_456_4_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261018_CHMP1A_chr16_89713739_ENST00000397901_length(amino acids)=278AA_BP=
MLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPL
PATSASAPAPLVPATVPSSTAPDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQ
NQMNGGPFYSQNPVSDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKGWYEGVMNGVTGLFPGNYV

--------------------------------------------------------------
>456_456_5_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261018_CHMP1A_chr16_89713739_ENST00000535997_length(transcript)=4086nt_BP=2144nt
ATTTATGCATTAAGTGGTTGCTTAGATTTAAGGTGAGTACCCAGAACATGAAGATGGGTGGGCTGCCGCGTACAACACCTCCAACTCAGA
AGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAGTC
GAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGCCCCTGCTGGCTCTG
CTGGCACTCCTCCCCTTCCTGCTACTTCTGCATCTGCCCCTGCTCCTCTTGTTCCTGCTACTGTCCCTTCCTCCACTGCCCCAGACGCTG
CTGCTGGGGGTGCCCAGACCCTTGCTGATGGCTTCACTTCTCCAACTCCCCCTGTTGTTTCTTCCACTCCCCCTACAGGTCATCCTGTAC
AGTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTT
CACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGTTTCAGATACACCACCTCCACCGCCACCTGTGG
AAGAACCAGTCTTTGATGAGTCTCCCCCACCTCCTCCTCCTCCAGAAGATTACGAAGAGGAGGAAGCTGCTGTGGTTGAGTATAGTGATC
CTTATGCTGAAGAGGACCCACCGTGGGCTCCACGTTCTTACTTGGAAAAGGGTTGGTATGAGGGAGTTATGAATGGAGTGACTGGGCTTT
TTCCTGGGAATTACGTTGAGTCTATCATGCATTATTCTGAGTAAAGCTCAGCAGGGCTGTGCTTGCCTCACAGGAATAGTCAGGTCTTCC
CAGATTATCTGAAGGCCCTGGGGATTCCACTCCAGTAAAGTAGAATGAAGGATACAAATGATAAAAATTACACTTTTTTTTTTGGTTTAT
TCCCCAGTATTAAAAACAAAGCAAGCTGAGTCTGAACAAATGGATCTTTCTGCCATCATTTGTACAATGCTGAGCTGTCTGGATTGAAAT
AAAATGACCATTTTTATGTATGTCAAAGGTATAACAGCATAACTGTGTAGCCAAAACAAAATCAGATTAAGACTGATTCAGAAAAATCTG
GGATCTTTCTCAGGAATACTGTATACCCTTGGGATTTCTCCTCCTGCAGAATCTGTGGCATTGGATGTTCTTCATTGCCTGTGCTAAGGG
GTTAACCTCATGGCCCAGTGGGTACCCTAGCCCCTTCTTTTCTTCCACTTGTATGAAGAGGAGGGAACCAACATTTAAATACCACACTTA
ACCATTTTTACAATTATTTCAGATGGCTTTTTTCCTCTGTGACACTGTAAATTCTGCATTCTCTCAGCACTTGAGTGCACCAAACGAGTG
AATGCTGAACTCACTTGCATCCCTTCATGTTTCTGTTTGTGGATTATAAGGATGATGAAATGTGAAAGTCTCCCAACACTCTGAGGGTGG
TGAACGATTGCCACCCGTTTGATTTTAATGTGCTGCTGCATGAGACTGCATTGTTGCTAATGGCCAGTGTACCCAGATGTGAAGTGTGGT
AGGCTGGTTCATATGTGGAGGTGGGTGTGTGAAGCTAGACACGAAGGTCCCTAAGGTTCTGAAGAGACTTGAACTGTGGAAATGCTCTTA
GCAGGCATCCCGAACCCCTGCTTCGGTGCTGTTTTGAGGAGTAGGATCTTGGAGTTCAGACCAACTATGACTATCATTTCCTTCACTATC
TAGAAAAACGCTATTCTACTTTGGAAGAGAATAGTAGTTATTTTCAAGTCTCCTGACAGTCACTGGGAGTACAAGGTTTGCTAATGTGCT
CTCTGGACGTTATTAATGGCCAGTATTAGTTGCTGCTGTATTACTGACTCGCTTAGCTGTAGAAAGGGTAATACTCTCCTGATTTTGTAT
GATTGGACTCTTAAGTAGCTGCTGTTAGTCAGAATTAAAACCCATCTCAGACTAAGAATATAATGAATAAGATTAATAGGCCAAAATATG
TATCTAATCACATTGATAAAAATTAATATAACTGACACAATAAAACACATTTCCCCCATCTGTACAATAAATACGTGACCAAGAATATGG
CCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGC
AGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCA
TCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTG
TGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGA
TGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTC
ACCTGCCAGGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTT
CTGGGGGTGATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGA
CTCTGGGGCAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACC
ACCTCAGCGGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCA
CCCAACGCTGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGA
GCCCCCTGGCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCA
AGTGTGCCCACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGA
CAGGGAGCCTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTT
CCTTGGGGCCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGC
CTTCCCAGCTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAA
CCTGCCATTGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCT
TTTCCATTTCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGG
CTGGCAGGGAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCA
GTGGTGTCGTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCA
GGGAGGGGCTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCA
TCGTGGGTAACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAG

>456_456_5_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261018_CHMP1A_chr16_89713739_ENST00000535997_length(amino acids)=278AA_BP=
MLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPL
PATSASAPAPLVPATVPSSTAPDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQ
NQMNGGPFYSQNPVSDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKGWYEGVMNGVTGLFPGNYV

--------------------------------------------------------------
>456_456_6_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261018_CHMP1A_chr16_89713739_ENST00000550102_length(transcript)=2660nt_BP=2144nt
ATTTATGCATTAAGTGGTTGCTTAGATTTAAGGTGAGTACCCAGAACATGAAGATGGGTGGGCTGCCGCGTACAACACCTCCAACTCAGA
AGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAGTC
GAGAGAACAGTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGCCCCTGCTGGCTCTG
CTGGCACTCCTCCCCTTCCTGCTACTTCTGCATCTGCCCCTGCTCCTCTTGTTCCTGCTACTGTCCCTTCCTCCACTGCCCCAGACGCTG
CTGCTGGGGGTGCCCAGACCCTTGCTGATGGCTTCACTTCTCCAACTCCCCCTGTTGTTTCTTCCACTCCCCCTACAGGTCATCCTGTAC
AGTTCTACAGCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTT
CACAAACAAGCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGTTTCAGATACACCACCTCCACCGCCACCTGTGG
AAGAACCAGTCTTTGATGAGTCTCCCCCACCTCCTCCTCCTCCAGAAGATTACGAAGAGGAGGAAGCTGCTGTGGTTGAGTATAGTGATC
CTTATGCTGAAGAGGACCCACCGTGGGCTCCACGTTCTTACTTGGAAAAGGGTTGGTATGAGGGAGTTATGAATGGAGTGACTGGGCTTT
TTCCTGGGAATTACGTTGAGTCTATCATGCATTATTCTGAGTAAAGCTCAGCAGGGCTGTGCTTGCCTCACAGGAATAGTCAGGTCTTCC
CAGATTATCTGAAGGCCCTGGGGATTCCACTCCAGTAAAGTAGAATGAAGGATACAAATGATAAAAATTACACTTTTTTTTTTGGTTTAT
TCCCCAGTATTAAAAACAAAGCAAGCTGAGTCTGAACAAATGGATCTTTCTGCCATCATTTGTACAATGCTGAGCTGTCTGGATTGAAAT
AAAATGACCATTTTTATGTATGTCAAAGGTATAACAGCATAACTGTGTAGCCAAAACAAAATCAGATTAAGACTGATTCAGAAAAATCTG
GGATCTTTCTCAGGAATACTGTATACCCTTGGGATTTCTCCTCCTGCAGAATCTGTGGCATTGGATGTTCTTCATTGCCTGTGCTAAGGG
GTTAACCTCATGGCCCAGTGGGTACCCTAGCCCCTTCTTTTCTTCCACTTGTATGAAGAGGAGGGAACCAACATTTAAATACCACACTTA
ACCATTTTTACAATTATTTCAGATGGCTTTTTTCCTCTGTGACACTGTAAATTCTGCATTCTCTCAGCACTTGAGTGCACCAAACGAGTG
AATGCTGAACTCACTTGCATCCCTTCATGTTTCTGTTTGTGGATTATAAGGATGATGAAATGTGAAAGTCTCCCAACACTCTGAGGGTGG
TGAACGATTGCCACCCGTTTGATTTTAATGTGCTGCTGCATGAGACTGCATTGTTGCTAATGGCCAGTGTACCCAGATGTGAAGTGTGGT
AGGCTGGTTCATATGTGGAGGTGGGTGTGTGAAGCTAGACACGAAGGTCCCTAAGGTTCTGAAGAGACTTGAACTGTGGAAATGCTCTTA
GCAGGCATCCCGAACCCCTGCTTCGGTGCTGTTTTGAGGAGTAGGATCTTGGAGTTCAGACCAACTATGACTATCATTTCCTTCACTATC
TAGAAAAACGCTATTCTACTTTGGAAGAGAATAGTAGTTATTTTCAAGTCTCCTGACAGTCACTGGGAGTACAAGGTTTGCTAATGTGCT
CTCTGGACGTTATTAATGGCCAGTATTAGTTGCTGCTGTATTACTGACTCGCTTAGCTGTAGAAAGGGTAATACTCTCCTGATTTTGTAT
GATTGGACTCTTAAGTAGCTGCTGTTAGTCAGAATTAAAACCCATCTCAGACTAAGAATATAATGAATAAGATTAATAGGCCAAAATATG
TATCTAATCACATTGATAAAAATTAATATAACTGACACAATAAAACACATTTCCCCCATCTGTACAATAAATACGTGACCAAGAATATGG
CCCAGGTGACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGC
AGAACCTGGACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCA
TCATGCAGATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTG
TGCGCAGCCAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGA
TGTGCTGGAAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTC

>456_456_6_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000261018_CHMP1A_chr16_89713739_ENST00000550102_length(amino acids)=278AA_BP=
MLRFKVSTQNMKMGGLPRTTPPTQKPPSPPMSGKGTLGSSGSSGGSHPSSRSSSRENSGSGSVGVPIAVPTPSPPSVFPAPAGSAGTPPL
PATSASAPAPLVPATVPSSTAPDAAAGGAQTLADGFTSPTPPVVSSTPPTGHPVQFYSMNRPASRHTPPTIGGSLPYRRPPSITSQTSLQ
NQMNGGPFYSQNPVSDTPPPPPPVEEPVFDESPPPPPPPEDYEEEEAAVVEYSDPYAEEDPPWAPRSYLEKGWYEGVMNGVTGLFPGNYV

--------------------------------------------------------------
>456_456_7_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000295851_CHMP1A_chr16_89713739_ENST00000253475_length(transcript)=24083nt_BP=22116nt
CCGGCGGCGCGGGCGAGGGTGGGAATCTTTTTCGGGCTCCCGGGGGCGGAGGGAAGGGAGCGCGCGTGCGCGCGCCCGGCCGGCCGTCGC
CGCGGTGACCGTCCTCGGAGTCCGTCGGCTCGCGCCCCGCCCCCGTCGCCCCCTCCCCTGTCGCGCGCTGGGGCTGTTTCTCGCTCCTTC
CGAGTTACCGCCGCCGTCGCCGCCGCTCCTCCTCTCCCGGTCCTGGGTTTCCTTGGCGCTGCGGCCGCCGCTCCCTCTGCGACCTGTATG
AGGAGGAGGAGGAGGAGGATGTGAAGATGGCGGAGCTGCAGATGCTGCTGGAAGAGGAAATCCCGGGGGGCCGCCGGGCCCTCTTCGACA
GCTACACAAATCTGGAACGGGTGGCCGATTACTGCGAGAACAACTACATACAGTCAGCAGATAAGCAGAGAGCCCTAGAAGAAACCAAAG
CCTACACCACCCAATCCTTAGCAAGTGTTGCCTATCTGATAAACACCTTGGCCAACAATGTCCTGCAGATGCTGGATATCCAGGCATCCC
AGCTACGAAGGATGGAATCTTCAATCAATCATATTTCACAAACAGTTGATATTCATAAAGAGAAAGTTGCAAGAAGAGAAATTGGTATTT
TGACTACCAATAAAAACACTTCAAGGACACATAAGATTATTGCTCCAGCCAACCTTGAACGACCAGTTCGTTATATTAGAAAACCTATTG
ACTATACAATTCTAGATGATATTGGACATGGAGTAAAGTGGTTGCTTAGATTTAAGGTGAGTACCCAGAACATGAAGATGGGTGGGCTGC
CGCGTACAACACCTCCAACTCAGAAGCCCCCTAGTCCCCCTATGTCAGGGAAAGGGACACTTGGGCGGCACTCCCCCTATCGCACACTGG
AGCCAGTGCGTCCTCCAGTGGTACCAAATGATTACGTACCTAGCCCAACCCGTAATATGGCTCCCTCGCAGCAGAGCCCTGTGAGGACAG
CTTCTGTGAATCAAAGAAATCGAACTTACAGCAGCAGTGGGAGTAGTGGAGGGAGCCACCCAAGTAGTCGGAGCAGCAGTCGAGAGAACA
GTGGAAGTGGTAGTGTGGGGGTTCCTATTGCTGTTCCTACTCCATCTCCTCCCAGTGTCTTTCCAGCCCCTGCTGGCTCTGCTGGCACTC
CTCCCCTTCCTGCTACTTCTGCATCTGCCCCTGCTCCTCTTGTTCCTGCTACTGTCCCTTCCTCCACTGCCCCAGACGCTGCTGCTGGGG
GTGCCCAGACCCTTGCTGATGGCTTCACTTCTCCAACTCCCCCTGTTGTTTCTTCCACTCCCCCTACAGGTCATCCTGTACAGTTCTACA
GCATGAATAGGCCTGCCTCTCGCCATACTCCCCCAACAATAGGGGGCTCGTTGCCCTATAGACGCCCTCCTTCCATTACTTCACAAACAA
GCCTTCAGAATCAGATGAATGGAGGACCTTTTTATAGCCAGAATCCAGTTTCAGATACACCACCTCCACCGCCACCTGTGGAAGAACCAG
TCTTTGATGAGTCTCCCCCACCTCCTCCTCCTCCAGAAGATTACGAAGAGGAGGAAGCTGCTGTGGTTGAGTATAGTGATCCTTATGCTG
AAGAGGACCCACCGTGGGCTCCACGTTCTTACTTGGAAAAGGGTTGGTATGAGGGAGTTATGAATGGAGTGACTGGGCTTTTTCCTGGGA
ATTACGTTGAGTCTATCATGCATTATTCTGAGTAAAGCTCAGCAGGGCTGTGCTTGCCTCACAGGAATAGTCAGGTCTTCCCAGATTATC
TGAAGGCCCTGGGGATTCCACTCCAGTAAAGTAGAATGAAGGATACAAATGATAAAAATTACACTTTTTTTTTTGGTTTATTCCCCAGTA
TTAAAAACAAAGCAAGCTGAGTCTGAACAAATGGATCTTTCTGCCATCATTTGTACAATGCTGAGCTGTCTGGATTGAAATAAAATGACC
ATTTTTATGTATGTCAAAGGTATAACAGCATAACTGTGTAGCCAAAACAAAATCAGATTAAGACTGATTCAGAAAAATCTGGGATCTTTC
TCAGGAATACTGTATACCCTTGGGATTTCTCCTCCTGCAGAATCTGTGGCATTGGATGTTCTTCATTGCCTGTGCTAAGGGGTTAACCTC
ATGGCCCAGTGGGTACCCTAGCCCCTTCTTTTCTTCCACTTGTATGAAGAGGAGGGAACCAACATTTAAATACCACACTTAACCATTTTT
ACAATTATTTCAGATGGCTTTTTTCCTCTGTGACACTGTAAATTCTGCATTCTCTCAGCACTTGAGTGCACCAAACGAGTGAATGCTGAA
CTCACTTGCATCCCTTCATGTTTCTGTTTGTGGATTATAAGGATGATGAAATGTGAAAGTCTCCCAACACTCTGAGGGTGGTGAACGATT
GCCACCCGTTTGATTTTAATGTGCTGCTGCATGAGACTGCATTGTTGCTAATGGCCAGTGTACCCAGATGTGAAGTGTGGTAGGCTGGTT
CATATGTGGAGGTGGGTGTGTGAAGCTAGACACGAAGGTCCCTAAGGTTCTGAAGAGACTTGAACTGTGGAAATGCTCTTAGCAGGCATC
CCGAACCCCTGCTTCGGTGCTGTTTTGAGGAGTAGGATCTTGGAGTTCAGACCAACTATGACTATCATTTCCTTCACTATCTAGAAAAAC
GCTATTCTACTTTGGAAGAGAATAGTAGTTATTTTCAAGTCTCCTGACAGTCACTGGGAGTACAAGGTTTGCTAATGTGCTCTCTGGACG
TTATTAATGGCCAGTATTAGTTGCTGCTGTATTACTGACTCGCTTAGCTGTAGAAAGGGTAATACTCTCCTGATTTTGTATGATTGGACT
CTTAAGTAGCTGCTGTTAGTCAGAATTAAAACCCATCTCAGACTAAGAATATAATGAATAAGATTAATAGGCCAAAATATGTATCTAATC
ACATTGATAAAAATTAATATAACTGACACAATAAAACACATTTCCCCCATCTGTACAATAAATACAGCTTCAAATTCAGTGGAGTCTGTA
GGGCAGATAACTTTAATCATCACTACTGTAGTCAGTATAAGAAATGCTGAAAAAAATCCAGGAGGGCTTGTCTCTTTGTGGGTGGTCACT
GTGATGTTGGGCCAGCTCCTGTTCAGGTCCAGAGCTGCTAACGTGGGTTCTACTCAGTCCCAGTGACTTGGCCAGAATAGAGCTTTGCCA
GGTAACTGCCCTGTGCTAGGTGAAAGGGGAAAAGCAGTAGCTGGATATATTTCAAATGAGGTTTTGAACAAGTTCAGAAAGTGGAACTTG
ATTGAAAAGTGAACAAGTGTAGTAGTGTGTGAGAAAATTCAGATGGTGTCGGATGCAGAAGTTAATATTCCACTTAATGTTATCTGAGCA
TTAAAAATCATCAGCATTTAACTGAGACCCCACTATAGAGTTTCCTTATCAAGACTTTTTGGTTTTAAAGTTGTTTTTAATGCATTGCAA
GTTACAATAGCTATTTTGCTTTTAGATTTTTCCCAGCACTTTGTATTTATTAGCTTTCATTAACTTGCCTCCAGTATACATTCCACTTCG
TGCTTTTCTTAGGTCATTTCTACATCCCTTATTCCTTGTTTTCCTGCAGTGTAATGGCCCTGAATGTCCTCTGAGCCTTCAGCTCCATTA
TGGACCCAAACTAGACTATACTTGGATAAGTTAAGCTCTTCTTCGTGTACTGGTCTATAATTAGAAAAACTGTTTTAAATTAGATGTTCC
CATTATTTATTTAAACAGCTTTTTGCTGAGAAAGCTTAGTGGATTAATGAGGCAGAGGGTGTTTTGAAATCCAATAAATAGTTCCCACAG
GCTGGGTGTGGTGGCTTATGCCTGTAATCCCAGCACTTTCGGAGGCCGAGGTGGGTGGATCATGAGGTCAATAAATTGAGACCATCCTGG
CCAACATGGTGAAACCCCATCTCTACTAAAAACACAAAAATTAGCTGGGCGTGGTGGCGCACACCTGTAGTCCCAGCTACTTGGGAGGCT
GAGGCAGGAGAATCACTGGAACCTGGGAGGCAGAGGTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGTGACAGAGCGAGAC
TCCATCAAAAAAAAAAAAAAAAAGTTCCCACAGCTCACCACTACAGAAGCAGGGAAGACAACTATGCAGAAAACAGAGTTAGTGGCGGTC
AGCAGGAATGCAGCTGGTCTTTTGGACCCCTACGGGATGGGGGCAGTGCAGAAGACACTGGTGAAGTCCTTTATACTGAAGACCTGTGGT
TGGGAGCAGGGGTAGTCCATGGGTCTGCTGATTTTTTTTCCCTATTTAGTACTAATGTGTGTGTGATCTTTGTTTTACAAACAGTACCTT
TTGGGTTTTCTGCATATTTTATAATTTTTGTACAGTTTTGAATTCTATAGATTGTCTTGGAAGGATACTGTGTGATGGGTCAGGCACACA
GTAATTGGAGACTTTTAATGTATGTAATATTTCATAGATTGCATGCTATTAATCATCTGTGAGGGTAGTATTTTTTGTTTTATTGTAAGT
TTCCCTCTTTTTTTATAAATTAAAAGATGGTTGGTATTAGGAATTTCAAATGAATGCAGAAAATCTTACATGCTGTGTACTATTAATATT
ATAACAGACGATCCAAGTCCAAAATCTGACCAATAAAGCAACCATTTTATCAAGATAGAGGGATTCTAATGGGAGAGGGGATTCTTCCCT
CCTGAAGTTTGTGTGTCCAGTCCCCTTAAAAAAAATGAATAGTTGTCTTTTCTTGTCATATTAATACTCGAAAGTCCATGGTGGTATTAA
TGAAAGTACACTTTATTGTTGCCTTTGAACTTACGGCCAAGGCAATAAATCAGAAACAAAAATAGTGCCAATGTGTCAAAATCGACATCT
GAGAGATTCAGCCTCCCATTTGGAATAAATATGAATCTTCTAAGCTATCTTGTTTAATATTTTCCATCATTTAGCTACTTCCTATCTCCC
TCAGAGGCGCCTGCTGTTCCCATTTTAGAGTTGACAGTGGCCTGCTAATTTTGCTATGTTCCTAAAAGTTACTGGGTGTGAGACATTTTC
ATCCCCTCCTTTTTCCTACTGCTGGTGTTTATTATCCAGCTAGACAATATTTTATGCATATTTACCGTGATGTCTGGACCGTACCTGTGC
TCCTTGGCAGTTTATGTTGAAGATAACTAAAGATTTTTCTCTTTGGGAGGCATCAAAATGATGGTAGTTTGCTTTTATCTTTTTATGTTC
ATTTTCTTTTAGTAGGTGACCTTTCTGCATTAAGAACTGTTTTTATCTTTTACTACCTTTTCTTTTCTCCTTTGTGGAGACAGCATGACA
TGTCCTGAAGGTCACCTTTGCCTTTGAAAAAGGTTTGATGGAGGAATTCACAGGTGACTGACAAGTCTTTGAAAAGAATGGGATCTGCTC
ACTTCTGGTCTTTTTGGCCGGGAACTCCTGATTGGTGTTAAGGTGGTAATTTCCCCCATATAAGATTTAGAATCACTGAGTTTGAGCTAG
ATGAAATTTTTAAAATTTCTGGTTGTCTCATTAGACTGATGAGGTGAGTTTTCTTCTTCATATGAACAGCTAGTTAATAACAGCAGAGTT
CTCACTCAGTGCTCAGTACTTAATTTTCCACTGCACCACAACTGTCTTAACTAAATGTGCTGTATTTTTCTTTAAAAGTTAAGAGTTCTA
TTTGGTGTTTTCAGGAATATACGTGAAAAGACATGCCATGTTTTGGTAAATACCATCAGAGTTGTGTAAAGGCGTGTACTAAGTGCAATC
TTAATTTGTGGAAATAATCTTCATTTACCCCTCCTAAAACTACACTCAGTATAAACACTTTCCCATAAGGTGTGTGCAGTAAAAATGTTA
TATTACTCCAACACTGGCAGGAGCACAGCACAGCAGCCTTATTGGAGAGAGCCTTATAAAAGTGATTAAATGGAGGCATTGAGCTCATTA
CCTTTAAGTTTACTTTGTGCTGACCTTTGTTCCTGTTTTGAGAATCTCATATAATTATTAAAAAAAAAAAACAATTAAAACGAAACGGCG
GGGCCTAGCTGTGTATAAATGATCCTTGCTGAATATCTTAAGGTTTTTTGTAAGAAAAAAGAAAAACCAACAAAAAAAGCTTATTTTCAC
ATTAAAATGAAACCTCTTTTGCAACTTAAGAATTCTATGGAAAAGCAGTTTTTATCATATTTTGTGTCCATGCACCATTTTTCTTAAAAT
GGCTTACAAAAAAGAATGTAAACAATTTGTGATCTGGCCAGTTGTACTTTTAGCTCCCAGAGGGAGAGTTGGTGGTATTATGAGTTGAGT
AAAAACCATCCAGGGGAACTTGAGGGAGCAGTCTGTTGCCAGTAATGTTCCTTGTGTGCCATTAAACCACCTCCAGATGAGTGGAGGAAC
ATCACTTTTTAATTTTTTAATTGTATTTGGAATTGTTGCCGTGTACTAAGAACTTGACCTAAATAAAATCCCACAAAGTATATTCAGGTG
TCTTGTTAACTTATTTATATAAATAACCTCTTTTTCTAAGGTGGTATCTTGAGTTTACGTGTTAGGGATAATCTGACTTTTCTGTTGCTC
TAAACCAGGGAGCTGCCTTTTATTACTGAAGAAGTCGTCTTTTTAAATTTTCAAAGATTTAAAATGTTGAGCTTTAAATTTGATCTCAAG
TTTCTTCCCTGAAGACAGCTGTTCTAATTAAGAACTTTCTAATCCTGTTTTTGCTCCACTCGCACCTGGGGTTTTCTTACCACTTTTCTC
CAAATCTAATTCTGTTAATGTACAGTTTTTTTAATTCAACAGACAAACACTGAAGATGGGTGTTGACTAAAAAATATTGCAGACTGGTCA
GAAGTGAATCTAAAAGACAAACCACTAACTAGCCTGTGCTTTGTTGCTATGAGAGCCTAGATTATAAAAGAATTTTCTAATGATGTATCT
GAGGGTAGCAAGTAAGTTTGTCTTCACAATACCCAAAATGATGTTTCAGCTTTTCTCACTTTTCAAGCCCATCTTATTTCCTCTGTACCT
TTATTATTTTGGTATCATTAGGTAAGGTGAAGAATAATGTAGGAAACAAATACCCAGCTAAAACATTTATGGGTTTCTCGTATTTGTGAA
TAGGATTTTAGGCGTCAGAGCAGTCTTGTCTTGTCTCAAAGATAGATAGTATCCAATCTTTTGTTAATAAGCCTATTGCTTGACTTTTTT
GGGTTACTTTGGAATTACACATTTGGTTGAACGGCTTTGTGGATCTGGGGCATATGCCAATTAAGGGGCACATGCCATGCGTTCTGTTTT
CCTGTCAGCCTGTGTACACTGCTGCTTCTGAAGGCATAAGTACAGGTGCAGTTTCCACAACCACGTATGATTGACAGATGGTGAACGAAA
GGGGAAGGCTTCCACTTTTTTTGCCCTAGTTTGGTACATAATAAAGTGATTGCAAACACATTATACATTTATACATACCTTCACATGGCA
GTCCAACACGTAATTGTGACTCCAAAGATTTGAAACAAACAAAAGGCATTCCTTTTTGTATTACTTTACTTTGTACTTAGTTCTTTGTTT
AAAGAAGAAAAATCTTTTTTACCTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCACAATTTCAG
CTCACTGCAAGCTCCACCTCCTGGGTTCATGCCATTCTCCTGCCTCAGCTTCCCGAGTAGCTGGGACTACAGGCGACTGCCACCACTCCT
GGCTAATTTTTTTTTGTATTTTTAATAGAGACGGGGTTTCACCATGTTAGCCGGGATGGTCTCGATCTCCTGACCTCGCGATCCACCCAC
CTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCACCCGGCTGAGAAGAAAAGTCTTTCTTTAAAAGCTGTTGTCACTTAA
TCACCAATGTATTTAATGGCCAAATTTCCCTAGTTGGTATAAACTACTCTTAAAAGTTAACAAATTGAACATATCAAACTAGTTTATTTA
CCACACTTAATTTCTTCTGTGTATGGCCTATGTTTTGGGTACCCTGACATGAAATGCAAAACCAGATTCTTAATGGTGCCGATCCACAAA
CACTCAAAGTCCCCATGTTTAAATGAAATCTATGAATTTTTTTTATTAAGGATTTGATAAGCTGATATAATGAAAACATGTAAATGAAAA
ACATTTACACTGACTGTACGACTAGTGTGCTAAGCCATTACAATAGTTTACTGACATAACTGGCAAGAGTAACTTGGAAAATAACTTAAT
CCAGCAGAACAAAAACATCCTCAGAAAAACATCCTCAGTAGTACTGAATATATCTCTCTCATATATCTATCTATCTATCTATATATATAT
ATATATATATATAGCTTTGCACAATCAGGGAGCAAGGCACATAATGAAATGAGCATACATTTATGCAGAAGAAAATAATAGCAACAAAGC
TGCGAGAAAAATTGTAACTTCATCTTCACTGAGCTGTGCATAATCCTTTGAATAATAATGTCCTCTACCTGGTACATTATAATGAAGTTC
CTTGTCTTCTTCATGCTTTAAAAAAGTATACTTCTACATTGTATCTACCTATGGCAAAGCTCCCACAGCCTACAAGTTGGTGTGAGCCTT
GACTCTTGTTTTTTAAAGAACTGAGGGAGGGAGCAATCCCAGTTAAATATAATGTGCAATTCCCCTTTAACAGTAAACAATGTTTTTAAA
ACACTTAGCACAAGCTAATTTTATCTTAAATGTACATCTCTGTAAGAGTTCACTAGTGGCTGATAGTAAAATGAAGCAAAATTGTTTGAA
ACATTCCAGTTAATGCTTATTTTCTAGAAGGGGTTATTTTACAAGTAGCAAAAAAAAAAAAAAAAGTAGGAGGTGGGGAAATAATATGAA
AAACGGCAGTTTTTGGTATTAGGTTACAATAAATTTAACGAATGGACAGTTTGCAAAATATAAGGGTTTCTCCCCCTTTAGTGCTGCAGA
CAAGTTTTACTGCCTAAGACGTTGAGGCTGCAACAATCATGAGCTTGGTATTAGTAGCCATCCATGATAAACATAATTAATTCTCAACTT
AACCATCTATAAAATATGTAGTGTTCACCATCACCCTGACTCAATTCACTTCTCTAAATGTCTTTGGTAGAAAGCAGCCAGACCCCACGT
GGGTAGTGATGTCTCTTGTGAGACACTTTTCATTTCTGCCAAAACTAGAAATACCACCTTCCTTTACTTTCATTAGCACCTCAAAGTTTG
CTTGCTGGATTTCTTTAAAAATATTCTGCCAAAAGAGTTGAAGGCACTGGGGGTTTACAGCAAGTATTTTCTCTTTAAAACGGTTTATTA
CTTCAACAAGCAAAGAGCAAACCAACTGGAGAAATGTATGTTTTTTCTTTTTATTTATCAAGTTTTATTCTACAGCTAAATTTCAGATTT
CTTTTACATATAGACCTTGCAAGGGCACGGTAAGAACTGAGCACTTGTTTTATTTGAGGGATAAAGGTGTAGAAATTTTCTCTTTGAATT
TTATAAGGAAAGGCTGGGTACAGTGGCTCATGCCTGTAATCTCAGCATTTTGGGAGGCTGAGGCAGGAAGATCACTTGTGGCCAGGAGTT
TGAGACCAGCCTGGGCAACACAGTGAGACCCCCATCTCTACCAAAAAAAAAAAAAAACCTTAAAAGATAATAAGTATCTAATTCTTTTAT
ACTTGCATTTCTCTTTGGATCAAATCTCAACTTTGTGAGAGGTCATACATTTCTACAGGGTTAGGAGTACCCTGCATAATTTATACAAAT
GTAAAGTGTATATTAAAAAAAAAAAAGTGAAAGTTACCTGCAATCTAAAGGGTTTTCTTCCCCTAGAAACAGTCACCCTCTCGTCAAGTG
TATGACCCAATTATACCTATTTTATGAAAAGCAAGGCATCACATTGATAACCATACAGGATCCTATGGGTTTAACTGGTCTAAACTTGAG
TGGATTAAATCAGTTGTAATTAGTTAGCTCTGTAGGTATATGAAAAACTTTTGGTAATGTACAAAAATAGGAATGGGTTTTTTACCTGTT
TAAAGTCACTTTGTGTTTATAACAAAATTACTTTTAGCTGAGGAACAAAGGTGACAAAGATTTCTGTTGGTGGCTGAGAGTCAAAGCAGG
CCAATCCACACCATTACCTGAAATATTTTTCAGGCTAATTTATAACTTTATGGATTTCCTCGATACAAGTTTATTAGTTTATTCTCCATA
TACAAGTTTATTCTCCCAGAATAGCAGCAAATAAAACTTGAATTGGATGTACAGCTCCTAATAACCTTGATGTCAGAGTTGTCACTTGGT
TGGAATTATTATGATCCCCCAATTTAAATTTTCTTGATAAACTCAGCGTTGTTTGTTTTCAGTGACAAGAAAACATACATGGAAAGGGGA
CCCAAGACAGTTCACCAAGATAGTTCACAGCCCTTTGCAGGATATGCCTTTGGTGGGTGGGAGCACCTAGATTTTAGAGGACTATAAAAC
GCCATGTTTACTTTGTTTGAAATTTTCTGATGAAAAGTCTTTTGTAACTTAACATTCCACATTTTCATTTAAAAAGTCCCAGAAATATAA
ACTATCCAATTTACAACTAAGGTGGGTATCTGTAAAAACCTTAAGAATAGTTACTCTTCCCAAGAGAATTACAGCGTCTAAGGGGGGGAA
AGAAAGCATCTGAGCAGTAAAAGTCAAGCTGGTAAAATCCAATACAGAATATCTAATAAACCATAAGTTATTTTACTGAGAATAGATTCT
GCTGCCCTACAGCATTGGTGCCAAAACTCTAAGCATAGAGTGATTCTACTTTGAAATTATCCATAGTAGAAATTAGGAGTGTCACTAATT
AAGCAAGTCACTACCTCTAATAAGCACCTGTTTGCACTGCCCTCAGCAGCAGGATGAGTTAATCCATGCTGTTCACTTTTCAGTACAGCC
AAGTCAACTGCACAGACTTGAAGCAGCCAAGCTGGGTGAGAGCTGCAGAGCAGAGGGCAGTGAAAGAAGGCACAGTACTAGTGTCGTGCG
GCAGTAGATGCTTTCCATGAATACACCAGAGAAAAAGAGCTACAGAAATACAGTCTAGGAAAAGCTACATCCCAACAAAAATCCAAATTA
AAGAAAACCCACTAGGGAGTAAAACAGAAGTATAAAGTATCACTTTAGTGGTTTTTTAAATTCAGTTCATACATGAGGTTAAAACATTTT
TAATAGCCATTTCTGTCTGTGGAGGAATGTAAAGGGAAATGGCCTGTTGTCGGACAAGCCACTGGACTGGGGTTAAAATGAGTCTCCTCC
TCTAGCCTTACTCTCTTCCTGGCATCATTAGTGTTCAAAAGGATGTCTGCTATTCCAGGAAAACAGACCAGAAGCATCTGTTCAGGATGG
CTATCATCAGGATTGATACAAGCAAGAAATTCCAAGAAATCCTGCACTGAAAACATAAAGGCTGTTGTTTTAGGGCTCAAATCATGGGTG
AAAAAAGGTTAGCGGGTACATTTTTTCCCCCTCAAGAAAAACTGAAGTGTTGTCTACCTTCTCATGAGAAAATCACCACCACAATAAAAC
TCAAAACCTCAGGGATGAATACTTTGATAACTGGATTCATATTCTTACTAACTCTAACCCACAAATATGGGTGCCCCTCAAACTATAAAA
CTGCAGGCAGAAGACTATGAGAAATTCATTCATGAATCACAGTAGCGCTTGGCAATCTACTCAAACATTACCCAAATTTCTGTGCATGCT
TAAATTAACAATGCAGATGTGTTAAAGATCACTTCATAAATATCAAACACAAAACTTGGTGAACAATTTGAAAGACCTAAAAATTAATGG
TATATATTCTTATTGCTCCATAACCACATGAACATAACCGAACAATATTCTGGAGATGTAGCAATGGAGAGGTGCTGTTCACTCTCTGTT
TACGATGCGGTTTTCGTGGAGTGTGGGTTATGCAAGACCTTGAGTATACTGTACTAATTAAGCACTTTTGCTCATTCTAGAATTATTTAC
CATCTCTTCCCCCACTTTACTGGCATCACTTTTTCCTTGTGGGACAATGTCAACTGATTTCTGCAGTTTGCATTGGTAATCATTAACAAT
AGGCACAGACTTTCATTACAAGATGTGCTCCCCTTATAAGTGCTGGGATGGCCCATTTTTATTCTCTTGTTTAGGAGCTGCTCTGAGATT
GTTTTATTCCTAATAGTCCAATTTATCATAAGTTGATGAGAGTACTTATTTCTCTCATGTACCAAGGAAAATTCACAGAAAAAAGCATAT
AGAAGTATAGTGTGTCGTTAGAGCACTGACTCCACGTTATACCAAACTGCACACGCATAAAACGTAATGTCAGTTACTGGACTTGGACTG
TCCCACTCCATCAGAACACCTAGTAACCTGAACTAATCACAACCAGGCTGCAGTCAGCAAGGGTCCTGGTAGCCCCAGTAGCTATAAATG
AAACTGTCTTCCCTCTCCATGTAGTCCCATACTTAATGAGCTTTTTGTATTACATATTATAACCCATATACAACCAGATTAATGACACCT
GTACAGGGGCCAGTTCTGTTCTCTCATCACCCTTCCCTTCTATAGAGCAATGCTCAAAAAATGCATTTTAGAAAATGATTTTGTTTTTCA
TAATGCACCATATTGGGGCACAGGATGTGTATATTTCATATACCAATTGTCTACAGATATGTAATAACACCTACCTAAAGCACATATTTT
AAGAAGGTAACTGGTGACCCAAAGACATACTGGGACAGAACATTACAGAGATAACTGTGTTATCCATCCTCTTAAAATCAATCAAAGTGA
GGATCATGAAGCCAAGTTGATAAAGCTTCATAAAACAGTACTAAAAAGGAACTATCCAGAATTATAGCACTAATTATCCATGTATTGTAG
GCAAAGAGCTTATCTGTCAGCACATCCTAAATGTGGGTGGATCACTGCAGCAGTACTGCAGCTAGAACAGCTGAGTTAATTACGCCATGT
ATTTACTTTCTATGCACAACCACATACAGATGATGTCTGTGAACATTTCCCCATCCTGCACTAGTTACCCGTTCTATGAAGCTGAGAGAT
TTTCCTGATTTAAAGTGCCCCTTCATGTATAGCAATGAAGTGTCAGTCAAGCAATTCTAACTTCAGCCAACTGGGGAAAAACAAACACAA
AAGCCTTATAGATACACCAAACATTCTGGTGATTTTTCTCAACCAGAAATAGCACATTCTACATCTATTCCTTAGTTATATAATACACAA
CATGCACGAATAGGCTACACATGGACAGACACTTATAAATACCTTCTAAATAAGTGATTAGAAGTTTTTGGTCCAATCCACATGATATAG
AAATCTTAAGAGACAACACACATCCCCTTCTATGCCTCTTCCACCCAAAATACAGAACACCCATTTTCAGATTAGGAGAGAAAAGGAATA
AATAGAATAACTCTCAGCTCTCTCTCTATATACACATACACATACATATATGTATACATATATACACACACTGTACAGCTGTGTGTACAT
GCACGTGTACACACACACATACACATATAGCTGGACACTACCTGAATAACATCATACCAGGAGGCTCTGAACACCTGAATTCACAGATGA
TCAGGTGAGCTGATTGTAGCAGTGATTACAGATATCATGAAAATAAAGTCCTATGGTGGCTACCAGTCTCTGGAGAGCTTGGTGTTCTGG
TCTCTTTTGGGGGGAGCAGGAGGGGGTCCTCTCCGCAACGTTGCATAGCCTGATATATGACTGCCTCCGTAACCAGCCTTCTGTTGATCA
GACAGCAGTTCAGGGGGTGGTGGAGGCAATGCCATATCATCCATGGTGGCTGTTGGTTCTGCTCTGGACATGCGGGAGGAGAGTGAGCCG
TGCCGAGTGATGGACTTTCGTTGCAGTGTCCTGTTGAGGTCAGCCAGGAATCCAGGCTGGACACTAAGGCTGGATTTGGGAGAGGTGGGC
ACTTGTGGCACAACTGTGGCCATTGTTGGCTGCTCAGAAATCTCAGCTTGAGTGAGGCGGGTGCTATCATTCCGTTTGGGTCGTGTGGGT
GGAGGGGCCTTCTTCACTGACATTTTAGACCATTGTTGTGGTTGAGGATTAACGACTGCCACTTTTGGAGAGGTGTTTCCCGAGAAAACT
GCTGGAATCTCAATGGGGGGCAGAGGAAGCTCTGTTTCAGGTGGAGGGGGTGGAAAATCAGAATCGGATGGAGGAGAAGGAAATTCCACC
ACGGAGTCCTTTCCACGCCCACTCAGAACAGGGGCTTTTGCTGACACACACCCTTGTTGGAGAACTCCAGGAAGGTTGACTCCAGAAAGA
TTGAGTTTTCCAGGCTTGGGGGGTGCTGCAGGAGGTGGTAGGGTCTCCTTGCTGGGAGACCCTGATTCTGCTGGCGGTGTAAACTTGCTG
ACTAGACTGTCCACCGAGGGTCTCTTGGGCTCGGGGTGCTCTGCACCACTGCTGGATTTAATGCTGGAGTTGCGCTGTGGGGTTGGGGGT
GGTTTCTTTCCCCCAGGGCTGGACGTCTTACTGGTCTTTTTGCCTGGAGATCCACTTTTGTCAGGGGTAGGAGAAGCTGTGGGTGGAGGT
GGTGGTGGTGGGGCTGGGACAGGTGATGGGGGTGGAGGAGGAAACACCAGGCTGCTTTCAGGAGGGGGAGGAGGGAAGTCCGGAGAAGGG
ACTGGGATGGAGCTGGGCTGCCACTTGGGCTTTGCTTTTACTGCAGGAGGGGACTGTGGAGCTACATTTGCTGGGACAGGCTTTAAGGGC
TGAGATTCCATGGCAGGGGGAGTTGGAGGGGGTGGAAACTGGCTGGCTATCTGCTTCACGACCGAGGGCACCGGTGACAGTGGAGAGGGA
GGGGGTTTTGCACAGAAGCTCTGTTGCTTGGGTAATGTTGGCGGGGGTACTGGAACAGGAGGGGTAGGGGGAGAGGGTGGAATGTAAGAA
GCAGGGAAAGCTGGCTGCTTTTTTGCTGGGGGCACTGGAGGAGTAGGTGTGGGTGGTGCAGCTTGAGTCACAACAGGTGCCACAGTCTTG
GTGCTGGTTGGTGCGGGGATGGTCACAAGGGGTTTTGGGGGAGCTTGGGGAGGGAGGGGTGCAGGGATAGGAGGAGGTGGGGGGGGTGTT
GGGGGAGCCACCTGAGTAATATGCTGAACTTGATGGATCTTCAGTGGAGGAGGCGGGGCACTGAACTGTGGAAGGGATGGGGCACACGGT
GCAGGCTTTAGCTGGGCCATGGCAGAGCCTGGGGTTGGGGGTGGAGGAGGGGGAGGGGGTGGTGGAACAACTCCATTGGGGGGTACCAGG
ATCTGAGGCTTCACTGACTGTGACTGCATCACTGGGGGTGTTGGCGGCTTAAACAGGGCCCCTGAATGCTGAGACGCATTCTGTAGCCGT
GTTATTGTGCTGTACTTGACGAACATTGGGGCTGCTGAGCCTGCAGAAGGTGCAGACTGGCTGGGGAGTGGGGGAGGAGGGGGTGGTGGA
GGGGGTGGTGGAGGAGGAGGTGGGGGTGGCGGAGGAGGTAGAGGTGGTGAAGGCTGTGAAGCAGTGTAGGGGGTGACTATCTTAGGTTGC
GGGGATAAAGGGGGCACAAGTGAAGTGTAGGGCCGATTCATAGACTCCATTCTGGCCTAAAAGGAGTATAAAAAGGGAGTGGGAGAGAGA
AAAACACAACAAACAAAACAGTTACAGAGGTAAGCTTTGATTGTGTAAAACTAAAAAGCAGGGAGTCTGGGACATGCATGAAAAGGATGC
AGAAGTTGGTGGTGATCATAAAGATGGACAATGTCAGGAAGGCTAAAATCTGATTGTGCGGGCAAGAAGGAAACAGAAAACTTGTTTTAC
CCCACAGTAAAATAGCTAGACCATCTAACAATCTAGGAAAAATGTCCGGCTGCAAAAGCTGTTTGAATGGTGACAGGATGCATGACTTCT
GACCTTGGCTGTATGACTTTGACACAGCCTGCCCTACATGGAACCCTCTGTGGCGGTCCTCTGAGCACTGGACTTCCAAGGGGAGATGTG
ATGGCTCCAGTTTACCTTTCAGTCCATGACTGCATCCACATCAAGCAGATGCTATAACTGGGTTTAGGAGGGCTTCCTGGTGGAATGAGG
ATGGCTTTTTGATGCTAGTAAGCTGACACAGGAGAGTATGAGAATGTTGAGCAGGCGTGCACAGTCACACAGGAATGAATAAGCTTGACA
CACACACTCGTGTTGGTGTGAGACAATTGCATCCAACATGCACAGAAGTCCAGCAATGCAGGTAAAGGGGGGACATTCTTTACATTTGTT
TTACTGGAAAATACATAAAGAAATGCTTTGTAAACATTATAGCAAAAGACTGTAAAAATATCATACAGAAAAAGCCAGAAGAAATTAAGA
GGAAGCTCTGGAAGGCTAGAATAAAGAAAATGTATCAAGAAATGGCAGCTAGCATTTGCCAACAACCAACCCATCTGGGTAGCTGAAATG
ATCACATCTGGTAGTTTATTTCGTGGAGCTAATCATGCACGATGGTGGTTCAGGTACTTTGAAAAGAGGAAAGGAAGGACCCTTGTTTTA
AAAACTTTAGGTACATCTTTTAGGCTCTTTGAACAAACTTTGAGGATCCAAGATAAACCATTTGTTTTCAATTTTGAATGACATCGAGAA
TGCATGGGTTAGTGAACTAGAAGGCTCATTATAGGGCTGAATTCTAATAGCCATCCGGACATTCACATGTTTCTTTTAAAATTACACAAA
AAGATTAGTCTGTGAGATTGGGATACAGGCGTCACCGAGGTTAATGTGTTTCCAGAGAACAACCCCTGACCTTAACTTGACCCTGTCTTG
GCTGCTTCAGGGGCGCAGGCCTTAGCTGTGCTGGCCTTCTCATTTGGCACCTGAGACTGAGGTAACAGGAGAAGAAATACAGAGTGATCA
AGCCTTAAAGCATTACTGCTGACAGCAGGGTTCCTACTCTTCTGAAACTCTGTGCAATAACGGACTTTGCTGCTTAATCACAGAACATTT
TGGGTCTGTGATTTTGTTTTCCTTGGCCTTACACATAACTAGGTTCTATAACTTAAAATGCACACGGATCTCACCATTAGTAATTTGGTA
AGGCAAAGGGGTTTTTCTTTAGCCATCCGAATTCTGTAAACCAACTTCTTTAGTACATTTTTAAAATACTAGCTCCATCCAAATTGATTA
AATGGGGGAAGGGAGAGAGAAATTATTTCTTAAAAGTTTGAGTCTCTAATAAGGGAGTTAAACTCAGTGTTTTGAGAATTTAGATCGTTA
GAACCAATTCTCAAATGCTCATTTCTGAAGGAAAGGGCTTCAGCCCCACATGGTGCTACTAAGGCCTTCTCTTCCCTGCGGGAGCCCAGT
TAGTGAACCACATATACGAATGAAGGAATAAAAGGAAAAATGTCCATTTATTCTCATTCGTGAATGTACCTGTATAAGTGATTCAGACCA
AAAGCACCCCCCACCAAAAAATTAAATAAATAAATAAAAACAATTATTAGTAAAAATAAAATAGTTGAGCCCAGGGTGCCACTGGTTCCT
CAATGATGGAGTGACCTCTTGCATATTGAAATGGTGACTACAGCCAGGACACATCCTTGCCTACACAACTACAGATGATGTCTGATAGAA
GGCCATGATGTCTTTCAAATGAACTGAAGAACCTCTCTATTTTCCTAATTATAGTCTTGCAATAACTATACTCATCCTTCAGTCTCACTG
CACAATATACTATGCAAGGCTCAGGAATCCAAAACTTTTAAGGGAAATGATTTTAATTTAGTCTTCCACATAAAGTATAATTTGAAAAAA
TTCATCAATGCCCAAAGAAATGGCAAAAGCATTAAAAAAAAAAAAGGTAAGGAATGAGTCTGAATAAATTAACCAATAAAGAAATAACTG
GACTGAATATGGTGGCTCATGCCTGTAATCCCAGGACTTTGGAAAGCCGAGGCAGGAGGATCGCTTGAGGCCAGGAGTTCGAGACCAGCC
CAGGCAAAATAGCCAGACCTTGTCTCTACCAAAAAATAAAAAACTAGCCAGGCATGGTGGTGTGCACCTGTAGTCCCAACTACTCAGGCA
ACTACTCGGGAGGCTGAGGTGAGCAAGCAGGCTGAGGTGGGAGGATCATTTGAGCCCAGGAGGCTTAAGTGAGCCCTGATAACACCACTG
CATTCCAGCCTGGGTGACGGGAAAGGGAGAGGGAGAGGGAGAGGAGGGGATGGGGAGAAGGAAGGAAAGGAAGGGAAGGAAGGGAGAGAA
GGAAGGGGAGGGAGGGAGGGAAGTGAGGGGAGGGAGGAAAGGAGGGAAGGAAGGAAGAAAAGAATAAAAAAGAAGAGAAAAAAAGAGAGA
GAGAGGCTGGGCACGGTGGCTCTCGCCTGTAATCCCAGCACTCTGGGAGGCTGAGGCAGGTGGATCTCGAAGTCAAGAGGTTGAAACCAT
CCTAGACAACAGGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTAGCATGTGCCTATAATCCCAGCTACTCGGG
AGGCTGAGGCAGGAGAATCGTTTGAACCCGGGAGGCGAAGGCTGCAGTGAGCTGAGATCACGCCACTGCACTCCAGCCTGGCGACAGACT
GACACTCTGTCAAAAAAAAAAAAAAAAAAAAAGGAAGAAGAAAAAAAGACAGGAAAGAAGAGAGAGAACTGTAAACAGCTTCTCTAGAAT
TTAGGGCATTTGCAATAGATGGTGTTTTGCCATCCAAACTGCTTAAAGGTGGAAAGGAAGAAATTGTTATTTCTTAAAAATCTGAGCCAC
TGATGAAAGAATTAAACTGCCAGTTTTTTTTGTTTTTTTGAGATTTTAAGTCATTAGAGCCAATTTGTAAAATACTCATTTCCAAGGGGA
AGTCAAATCAACAGGTCTCTCTGAACTGTCTTTACCCACTACAATTAGGAAGATTGAAAATTAATAAAGGAGACTGAAATAAGGCCAAAT
AAGATCCCCGATAAAGACATAAGAGAGCAACAATTTAAACCCAAAAGAATACCACAGAATTTTCAATGTAAATTAAAACGAAGCTGTTAC
CTTGCTGGACTCTTCCAACTGAGTGCCTCGTTTCCAGGCTTCAGAGAATACGGAGCTCACAATGCTCTGGGAACGGACGTGTCCTGCTGG
CTGGGTGTCAGAAACTCCGCTATCAGACTGATTGGAGTGGTTTGACTGAGACTCTGTTTAAAATAGTTTTTTAAACATAGGTTTAAAAGA
GTCAGTATTCTGACAATATTCATATGTATGTCTAGTTAGATCTTTTACACAAGGTCAAGTGCTGTGTACAACAGCACCAAGTTATTTTAC
TCATTTCATCATAAACACAGCCAGTATTTTCTACTAGAAAACTTCCCTTACCTTGGAATTAAGAAATCTCAGATTAGTGTTAAATATTTC
ACCATGAGAGACTGATAATTATAATAAATGATTCACATAACATTATTGGTATCCTGACACCCAGTCTTGCATGAAATCAACTCTAAACAA
TAAAAGAATTAATGAACCATCAGTAGAGGAGTCTCTCAATCATGTCTGCATTACATTGAGAATCAGCCTTTTTAATACCCCTGCCTTAAG
GTCACGCCAGAATTGTAACTTAGGAATTCGGATCTATACACAATGATTATTTCCTTTTTTCTAGCAATGAGCAATACTTAGAATTTGACC
CTCTAGTGCGAAGTGTGTTTCCTAGGGATTTAGGTATTGGACCCATAGGGTGGCAGCTGTGCTGTATCCTGGCCTGTCAGCAAGGCACAA
AAAAGTTTTGAAAGGAGTGGGGCCTGGTGGGAATGGCTGTGAGCATACAGTGTCTCTTTGCCGCCTGAGCAAGGAGGCTGAGGTGGGAGG
ATCATTTGAGCCCAGGAGAGTTAAGTGAGCTATGATAACACCACTGCATTCCAGCCTGGGTGATGGGAGAGGAAGGAAGGAAAAGGAAGG
GGAACCATGTTCTGGAAGGGTTGTTGGTTGGTTTTTTTTCCCCATTTTAATAAATATTTTCTTAGAATAGTTTTAAGATATCTACATATT
AGATATTTGAATATTAGAACAGTTTTAGCACAGAATTCCTACATACCCGGCATCCAGTTTACCCATTTAGCAATATGTTTGGTTTTAAAG
AAATTCTCCTTTGGGGAAAAAGTGTCCTCTTTTAATTTTATTCCCTTTTCCCCATTATTAACATGTTACATTACTATACTACATTTGTCA
CAACTAAGGAAATGTCCTGCTACTATTAACTACGCTCCACACTTTATTTGGATTTCACTAGTTTTTCCCTCATGTGCCTTTTCTGATCCA
GGACACCACGTCACAGTTAGTCATCATGTCTCCTATAACGGCTTCTCAGAATTTCCTGTTTTTGATGACTTAGACAGTTTTGAGGAATAG
TGGTCAGGTATCTTGTAGACTGTCTCTCAGTTTTGGTTTGTCTGATGCTTTTTCTCTTGATTAGTCTGTTTATGGAACTTGGGGAGGAAG
ATCATAGAGGAAAAAAGCCATTCTCACACACTATGTCAAAGGTCCCTATAACCAATGTGACTTAGATACTGACCTTGACCACATGGTTGT
GGCAGTGTTTGTCAGGTTTCTCCACTGTGAAGTTACCCCTAATCCCCGTTCCATAATCACTGGAAGCAAGTCACTAAGCACAGTCCACAC
TTGAGGACTTAGGTAAGCTCTACTTCCTTCAGGACAAAGTGTCTTCATAAATCATTTAGAAATCTACACAGGACAGTTCTCTCCTCTTCC
CCATTTATTTATTCAATGATTTATTTACATCAGTATAAACTCATGGATATTTATGTCCATGGGTTACAATCCTATACTATATTACTTATT
GTATTGCTCAAATTGTTCCAGCTTTGACCTTTGGAGCTCTTTCAGACTGGCTCCTCTGTGTATCCCTTTGACATATTCTCATCTTGTGTT
TTGTGAGACAGGGTCTCGTTCTGTTGCACAAGCTGGAGCACAGTGGTGTGATTATAGCTCACTGCAGCCTTGAACTTTTGGGCTCAAGCA
ATCCTCCTGCCTCAGCCTCCTGAGTTGCTAGGACTATGTGTACTACTAAGTCTGGCTAATTTAAAAAAAAAAAAAAAAAAAAGTTGTGGA
GATGGGGTCTTGCTGTGCTGCCCAGGCTGGTTTTGAACTACTGGGCTCACGTGATCCCTTAACCTAGGCCTCCCAAAGCATTGGCATTAC
AGGCGTCAGCCACTGTGCCTGGCCCTACTGTCGTTTTTTAAGCATTCCCTTACTTTCTGGCATTACAAGATGCTCTAGGCTCATCTTGTA
TATATTCTCTGCTGCAGCCCTATAATTTGCCATTTCTTTGAGAGCCTTGGTTTTCTTTTCTTTCTTTTTTTTTTTTTTTTTTGAAGAATG
GTATTAGAAACCATGATCTATTTAAGCAGCATCCTTGGCCAAAATTTAATAAAACGAAAAAACAAAAAGAAACCTCTATGATCTAGGGAC
TGGGTATTCTCATTGTTCCTGGGGTATCACTGCTTCTAGTCCTCAGTGGACAGCACTAGGAAATGTATGTGTATATACACATTCTAAATT
TGTTTTTACTTAATAGAGATGAAATAGAGTCATGCAGCTTTTAAATATACTACTAAAGTTATTATTTCTTTCATCACATCCAATGCAAAA
ATTTAAAAATTCTGCTTTTAGATGACATGGATCTCATTCATGAAACATTTTGAATTGAAAGAAGATTTATGTTAAGATGTAATCATAGCA
TGCACTTGTTTAAAGGATATAGGAATCTGAAGGAGTGCAGCTTCTTCATGGTTTCTGAGTACAAAGATTCTTTCCAAGTAATGTTTTATC
CCAAATTATGCATTAACAGTGTCCAGCAGTATGTATGTTTTGAATAAATTTTATAAATATAAATAAGTGACCAAGAATATGGCCCAGGTG
ACCAAAGCCCTGGACAAGGCCCTGAGCACCATGGACCTGCAGAAGGTCTCCTCAGTGATGGACAGGTTCGAGCAGCAGGTGCAGAACCTG
GACGTCCATACATCGGTGATGGAGGACTCCATGAGCTCGGCCACCACCCTGACCACGCCGCAGGAGCAGGTGGACAGCCTCATCATGCAG
ATCGCCGAGGAGAATGGCCTGGAGGTGCTGGACCAGCTCAGCCAGCTGCCCGAGGGCGCCTCTGCCGTGGGCGAGAGCTCTGTGCGCAGC
CAGGAGGACCAGCTGTCACGGAGGTTGGCCGCCTTGAGGAACTAGCCGTGCCCCGCCGGTGTGCACCGCCTCTGCCCCGTGATGTGCTGG
AAGGCTCCTGTCCTCTCCCCACCGCGTCTTGCCTTTGTGCTGACCCCGCGGGGCTGCGGCCGGCAGCCACTCTGCGTCTCTCACCTGCCA
GGCCTGCGTGGCCTTAGGGTTGTTCCTGTTCTTTTAGGTTGGGCGGTGGGTCTGTGTCCTGGTGTTGAGTTTCTGCAAATTTCTGGGGGT
GATTTCTGTGACTCTGGGCCCACAGCGGGGAGGCCAAGAGGGGCCCTGTGGACTTTCACCCAGCACTGTGGGGGCCTTCAGACTCTGGGG
CAGCAGACATGCTGCTTCCCATCAGCCAGAGGGGGTCAGGGCTGCCCTGTTGCCAAACAACTCCCTGAGGCCTCTCCGCACCACCTCAGC
GGGCAGGAGGTCCCACCATGTGGACAGACATAGCCCAAGGAGGCACCACAGGTCTATGTGTGCTGGGGGATGTCAGGTGCCACCCAACGC
TGTCCTGGTGGTATTTACAATGACATCCTCCTCCTCCATCACTCCAGGGGTGGTGTCTCGGCCGCCCCTACCAGCTGGCTGAGCCCCCTG
GCCTCCTGCGCTCCCTCACTTCCCTCAGTTCCCAAAGCTGCCCAGTCCATGGGGACAGAACCGTCACTCAGATCCACATTCAAGTGTGCC
CACCCTGCAGTCTTCATCCTCACTCAGCTGCTGCCTCTGGAGGTGCCTTTGGCCACATGTGCTGTGCTGTTTGTCTCCTCGACAGGGAGC
CTGTCCACCAGCAGGCTGCGGTCCCAGCGGGTGCGTCTGCAGCTCCTCCCCTTGGGCAGCCTGGTTCTCCCGGAGGACCTTTCCTTGGGG
CCCTGCTTCATGACGATGCTGCCTGTGTCACCCTCTACCATCTGTAAACAACTGGGTGCCTTCCCCGACCACACCCCAATGCCTTCCCAG
CTTGGAAGCCAAGGCAGCTGATGAAGGGAGCTCAGGAGAGCCGTCTTCAGCTGGGCTGGGGTTGGGGCTGCTGTGAGGAAAACCTGCCAT
TGTGGCCCTGGAGAGTCACCAGCAGCTCTTGGGAAGGACTTGCTGGGAGGCTGAGAGAGGCTTTGGGCACAGCCTGCTGTCTTTTCCATT
TCCTAAAGTTTACTTCATTGTCTTGAGGCTTCCAGGTTTTGTTTTTGTTTTTGCCAAAGTAGAAAAGGCAGGTGGTGGGCGGCTGGCAGG
GAGTGCGGGTCCCCGCCCCTCTTCAGTCCTGCCCTCCCCTCCTCAGTCCTGCCCACCCCGTGCAGCCCATGCTGAGGCTGCAGTGGTGTC
GTGGGTGTTACGTGCAGGAACGTGGAGACCCTGACGTGGGCTCACTGCGTTTGGTTTTCTTTTCAGAACTTGGGAGCCCCCAGGGAGGGG
CTAGTGTTGGTAGGTCCTAGACGTGGTTCCCTCCAGCCTCCCCAAAATCAACCCTGGTGTTGAGAGAACGTCCTTCTGTCCATCGTGGGT
AACAGCCTTGGGGAGGGTGCAGAGCTCTGCAGAGCCATGGGCCAGGTGGGGCTGCCTCAGTCCTGTCCCCTTGGGCACTGAGGAGAGGGG

>456_456_7_ABI2-CHMP1A_ABI2_chr2_204291992_ENST00000295851_CHMP1A_chr16_89713739_ENST00000253475_length(amino acids)=656AA_BP=36
MESMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALF
KPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLP
PQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQ
IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSG
SPGKKTSKTSSPGGKKPPPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQG
CVSAKAPVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLT
QAEISEQPTMATVVPQVPTSPKSSLSVQPGFLADLNRTLQRKSITRHGSLSSRMSRAEPTATMDDMALPPPPPELLSDQQKAGYGGSHIS

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ABI2-CHMP1A


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ABI2-CHMP1A


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ABI2-CHMP1A


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource