Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:LMBR1-LINC01006 (FusionGDB2 ID:45736)

Fusion Gene Summary for LMBR1-LINC01006

Fusion gene summary

Fusion gene information	Fusion gene name: LMBR1-LINC01006
	Fusion gene ID: 45736
		Hgene	Tgene
	Gene symbol	LMBR1	LINC01006
	Gene ID	64327	100506380
	Gene name	limb development membrane protein 1	long intergenic non-protein coding RNA 1006
	Synonyms	ACHP\|C7orf2\|DIF14\|LSS\|PPD2\|THYP\|TPT\|ZRS	C7orf13\|MY040
	Cytomap	7q36.3	7q36.3
	Type of gene	protein-coding	ncRNA
	Description	limb region 1 protein homologdifferentiation-related gene 14 proteinlimb region 1 homolog	-
	Modification date	20200313	20200313
	UniProtAcc	Q8WVP7	Q8NI28
	Ensembl transtripts involved in fusion gene	ENST00000353442, ENST00000354505, ENST00000359422, ENST00000540390, ENST00000430825,	ENST00000447933,
Fusion gene scores	* DoF score	14 X 11 X 12=1848	5 X 6 X 3=90
	# samples	20	6
	** MAII score	log2(20/1848*10)=-3.20789285164133 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(6/90*10)=-0.584962500721156 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: LMBR1 [Title/Abstract] AND LINC01006 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	LMBR1(156549087)-LINC01006(156265405), # samples:2
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner

Gene

GO ID

GO term

PubMed ID

Fusion gene breakpoints across LMBR1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across LINC01006 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	BLCA	TCGA-DK-AA76	LMBR1	chr7	156549087	-	LINC01006	chr7	156265405	-
ChimerDB4	BRCA	TCGA-AC-A6IX-01A	LMBR1	chr7	156589083	-	LINC01006	chr7	156265405	-
ChimerDB4	BRCA	TCGA-AC-A6IX-01A	LMBR1	chr7	156589083	-	LINC01006	chr7	156398458	-
ChimerDB4	STAD	TCGA-BR-7716-01A	LMBR1	chr7	156549087	-	LINC01006	chr7	156265405	-

Top

Fusion Gene ORF analysis for LMBR1-LINC01006

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-5UTR	ENST00000353442	ENST00000447933	LMBR1	chr7	156549087	-	LINC01006	chr7	156265405	-
5CDS-5UTR	ENST00000353442	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156265405	-
5CDS-5UTR	ENST00000354505	ENST00000447933	LMBR1	chr7	156549087	-	LINC01006	chr7	156265405	-
5CDS-5UTR	ENST00000354505	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156265405	-
5CDS-5UTR	ENST00000359422	ENST00000447933	LMBR1	chr7	156549087	-	LINC01006	chr7	156265405	-
5CDS-5UTR	ENST00000540390	ENST00000447933	LMBR1	chr7	156549087	-	LINC01006	chr7	156265405	-
5CDS-5UTR	ENST00000540390	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156265405	-
5UTR-3CDS	ENST00000359422	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156398458	-
5UTR-5UTR	ENST00000359422	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156265405	-
In-frame	ENST00000353442	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156398458	-
In-frame	ENST00000354505	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156398458	-
In-frame	ENST00000540390	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156398458	-
intron-3CDS	ENST00000430825	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156398458	-
intron-5UTR	ENST00000430825	ENST00000447933	LMBR1	chr7	156549087	-	LINC01006	chr7	156265405	-
intron-5UTR	ENST00000430825	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156265405	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000353442	LMBR1	chr7	156589083	-	ENST00000447933	LINC01006	chr7	156398458	-	1426	660	237	770	177
ENST00000354505	LMBR1	chr7	156589083	-	ENST00000447933	LINC01006	chr7	156398458	-	1343	577	154	687	177
ENST00000540390	LMBR1	chr7	156589083	-	ENST00000447933	LINC01006	chr7	156398458	-	1302	536	104	646	180

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000353442	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156398458	-	0.033432625	0.96656734
ENST00000354505	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156398458	-	0.027108544	0.9728915
ENST00000540390	ENST00000447933	LMBR1	chr7	156589083	-	LINC01006	chr7	156398458	-	0.040401466	0.95959854

Top

Fusion Genomic Features for LMBR1-LINC01006

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for LMBR1-LINC01006

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:156549087/chr7:156265405)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
LMBR1 Q8WVP7	LINC01006 Q8NI28
FUNCTION: Putative membrane receptor.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

1_19

141

491.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

41_62

141

491.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

84_110

141

491.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

1_19

141

532.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

41_62

141

532.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

84_110

141

532.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

111_131

141

491.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

20_40

141

491.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

63_83

141

491.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

111_131

141

532.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

20_40

141

532.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

63_83

141

532.0

Transmembrane

Helical

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

250_287

141

491.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

250_287

141

532.0

Coiled coil

Ontology_term=ECO:0000255

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

132_151

141

491.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

173_187

141

491.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

209_291

141

491.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

313_339

141

491.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

361_383

141

491.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

405_426

141

491.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

448_490

141

491.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

132_151

141

532.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

173_187

141

532.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

209_291

141

532.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

313_339

141

532.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

361_383

141

532.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

405_426

141

532.0

Topological domain

Extracellular

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

448_490

141

532.0

Topological domain

Cytoplasmic

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

152_172

141

491.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

188_208

141

491.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

292_312

141

491.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

340_360

141

491.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

384_404

141

491.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000353442

427_447

141

491.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

152_172

141

532.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

188_208

141

532.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

292_312

141

532.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

340_360

141

532.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

384_404

141

532.0

Transmembrane

Helical

Hgene

LMBR1

chr7:156589083

chr7:156398458

ENST00000354505

427_447

141

532.0

Transmembrane

Helical

Top

Fusion Gene Sequence for LMBR1-LINC01006

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>45736_45736_1_LMBR1-LINC01006_LMBR1_chr7_156589083_ENST00000353442_LINC01006_chr7_156398458_ENST00000447933_length(transcript)=1426nt_BP=660nt
GCCCCGCCCCCGCCCCGCCCCCGACTGCGCGGCGCCCGCCCTCCCTTAGTCAGAGCTGCTCGTCTGAGGCTGCTGAGGCGACGGCCGGTG
TCGTGGTCGCGGTACCTGTTCCAACACGGCTCGCGGGCCCGTGCCGGCTCCGGTCCCCGGCGCGGCTGTCCGAGCCCCTGCGGCGGGCGG
ACGATGGTGTGGCGGAGCACGCGGACGCGGGCGGCGCGGCGGCGGGCATGAAGGAGGATGGAAGGGCAGGACGAGGTGTCGGCGCGGGAG
CAGCACTTCCACAGCCAAGTGCGGGAGTCCACGATATGTTTCCTTCTTTTTGCCATTCTCTACGTTGTTTCCTACTTCATCATCACAAGA
TACAAGAGAAAATCAGATGAACAAGAAGATGAAGATGCCATCGTCAACAGGATTTCGTTGTTTTTGAGCACGTTCACTCTCGCAGTGTCA
GCTGGGGCTGTTTTGCTTTTACCCTTCTCAATCATCAGCAATGAAATCCTGCTTTCTTTTCCTCAGAACTACTATATTCAGTGGCTAAAT
GGCTCCCTGATTCATGGTTTGTGGAATCTTGCTTCCCTTTTTTCCAACCTTTGTTTATTTGTATTGATGCCCTTTGCCTTTTTCTTTCTG
GAATCAGAAGGCTTTGCTGGCCTGAAAAAGGCCCTCCTGGTGAGATCCCATCACGTCCCCTGGCCTCCAGTGTCATCTGCTCTGCATGAT
ATCTCCAGGGGGACCTCTCTGCTGGGCTCCAGGCCGCATGGCTGTGGGTGACCAGCATCATGTCCCACCGGGTCCCCTGCAGTCCCAGTG
CACCTGCCTGCTCATCCAGGGACCTGTCCTCACTGCCTGCTGCCTGCACTGTGTGGAAGGACAGAGGCTAAACGACGAAGCCTCGAGCTC
TGGTCTCATGGAAATGGCAGCCTGCCCACCACCCACGCTTGCCCAGCCTTTCTTCACGCAGGAAGAATATTTCTCAGCCCTCCGTTCTCA
AGACAGATGAGTGCTTTAGAAAGAGGACTCTGCAGCGGTGAGGAGGATGGAATGACAGGCAAAGCACGCAGGACCAGGAGATGGCTTCGT
TCCCTCAATCACTCATCCAAAGACGTTTAATGAGCACCTATTGTGTGTCAGGCATTGTACCGGGCAATGGGGATATCGTAGTCAGTAATA
AGTGAGGAGAGATGAGTTCATTTGTGAGAGGCTCTGACCAGTGGAATCAGAGGAAGGGAGTTCCCCTGGGTGGGCCAGGTTCAAAGACAT
TTTGGAAGTAGAATCTGCAGAACATGATGATCTTTTGGAAACAGGGCAGGGACGTGAATGAGCACGTAATGTCCCCATGGGTTTGTCTTT

>45736_45736_1_LMBR1-LINC01006_LMBR1_chr7_156589083_ENST00000353442_LINC01006_chr7_156398458_ENST00000447933_length(amino acids)=177AA_BP=0
MEGQDEVSAREQHFHSQVRESTICFLLFAILYVVSYFIITRYKRKSDEQEDEDAIVNRISLFLSTFTLAVSAGAVLLLPFSIISNEILLS

--------------------------------------------------------------
>45736_45736_2_LMBR1-LINC01006_LMBR1_chr7_156589083_ENST00000354505_LINC01006_chr7_156398458_ENST00000447933_length(transcript)=1343nt_BP=577nt
GCCGGTGTCGTGGTCGCGGTACCTGTTCCAACACGGCTCGCGGGCCCGTGCCGGCTCCGGTCCCCGGCGCGGCTGTCCGAGCCCCTGCGG
CGGGCGGACGATGGTGTGGCGGAGCACGCGGACGCGGGCGGCGCGGCGGCGGGCATGAAGGAGGATGGAAGGGCAGGACGAGGTGTCGGC
GCGGGAGCAGCACTTCCACAGCCAAGTGCGGGAGTCCACGATATGTTTCCTTCTTTTTGCCATTCTCTACGTTGTTTCCTACTTCATCAT
CACAAGATACAAGAGAAAATCAGATGAACAAGAAGATGAAGATGCCATCGTCAACAGGATTTCGTTGTTTTTGAGCACGTTCACTCTCGC
AGTGTCAGCTGGGGCTGTTTTGCTTTTACCCTTCTCAATCATCAGCAATGAAATCCTGCTTTCTTTTCCTCAGAACTACTATATTCAGTG
GCTAAATGGCTCCCTGATTCATGGTTTGTGGAATCTTGCTTCCCTTTTTTCCAACCTTTGTTTATTTGTATTGATGCCCTTTGCCTTTTT
CTTTCTGGAATCAGAAGGCTTTGCTGGCCTGAAAAAGGCCCTCCTGGTGAGATCCCATCACGTCCCCTGGCCTCCAGTGTCATCTGCTCT
GCATGATATCTCCAGGGGGACCTCTCTGCTGGGCTCCAGGCCGCATGGCTGTGGGTGACCAGCATCATGTCCCACCGGGTCCCCTGCAGT
CCCAGTGCACCTGCCTGCTCATCCAGGGACCTGTCCTCACTGCCTGCTGCCTGCACTGTGTGGAAGGACAGAGGCTAAACGACGAAGCCT
CGAGCTCTGGTCTCATGGAAATGGCAGCCTGCCCACCACCCACGCTTGCCCAGCCTTTCTTCACGCAGGAAGAATATTTCTCAGCCCTCC
GTTCTCAAGACAGATGAGTGCTTTAGAAAGAGGACTCTGCAGCGGTGAGGAGGATGGAATGACAGGCAAAGCACGCAGGACCAGGAGATG
GCTTCGTTCCCTCAATCACTCATCCAAAGACGTTTAATGAGCACCTATTGTGTGTCAGGCATTGTACCGGGCAATGGGGATATCGTAGTC
AGTAATAAGTGAGGAGAGATGAGTTCATTTGTGAGAGGCTCTGACCAGTGGAATCAGAGGAAGGGAGTTCCCCTGGGTGGGCCAGGTTCA
AAGACATTTTGGAAGTAGAATCTGCAGAACATGATGATCTTTTGGAAACAGGGCAGGGACGTGAATGAGCACGTAATGTCCCCATGGGTT

>45736_45736_2_LMBR1-LINC01006_LMBR1_chr7_156589083_ENST00000354505_LINC01006_chr7_156398458_ENST00000447933_length(amino acids)=177AA_BP=0
MEGQDEVSAREQHFHSQVRESTICFLLFAILYVVSYFIITRYKRKSDEQEDEDAIVNRISLFLSTFTLAVSAGAVLLLPFSIISNEILLS

--------------------------------------------------------------
>45736_45736_3_LMBR1-LINC01006_LMBR1_chr7_156589083_ENST00000540390_LINC01006_chr7_156398458_ENST00000447933_length(transcript)=1302nt_BP=536nt
AGAGCTGCTCGTCTGAGGCTGCTGAGGCGACGGCCGGTGTCGTGGTCGCGGTACCTGTTCCAACACGGCTCGCGGGCCCGTGCCGGCTCC
GGTCCCCGGCGCGGCTGTCCGAGCCCCTGCGGCGGGCGGACGATGGTGTGGCGGAGCACGCGGACGCGGGCGGCGCGGCGGCGGGCATGA
AGGAGGATGGAAGGGCAGGACGAGGTGTCGGCGCGGGAGCAGCACTTCCACAGCCAAGTGCGGGAGTCCACGATGAACAAGAAGATGAAG
ATGCCATCGTCAACAGGATTTCGTTGTTTTTGAGCACGTTCACTCTCGCAGTGTCAGCTGGGGCTGTTTTGCTTTTACCCTTCTCAATCA
TCAGCAATGAAATCCTGCTTTCTTTTCCTCAGAACTACTATATTCAGTGGCTAAATGGCTCCCTGATTCATGGTTTGTGGAATCTTGCTT
CCCTTTTTTCCAACCTTTGTTTATTTGTATTGATGCCCTTTGCCTTTTTCTTTCTGGAATCAGAAGGCTTTGCTGGCCTGAAAAAGGCCC
TCCTGGTGAGATCCCATCACGTCCCCTGGCCTCCAGTGTCATCTGCTCTGCATGATATCTCCAGGGGGACCTCTCTGCTGGGCTCCAGGC
CGCATGGCTGTGGGTGACCAGCATCATGTCCCACCGGGTCCCCTGCAGTCCCAGTGCACCTGCCTGCTCATCCAGGGACCTGTCCTCACT
GCCTGCTGCCTGCACTGTGTGGAAGGACAGAGGCTAAACGACGAAGCCTCGAGCTCTGGTCTCATGGAAATGGCAGCCTGCCCACCACCC
ACGCTTGCCCAGCCTTTCTTCACGCAGGAAGAATATTTCTCAGCCCTCCGTTCTCAAGACAGATGAGTGCTTTAGAAAGAGGACTCTGCA
GCGGTGAGGAGGATGGAATGACAGGCAAAGCACGCAGGACCAGGAGATGGCTTCGTTCCCTCAATCACTCATCCAAAGACGTTTAATGAG
CACCTATTGTGTGTCAGGCATTGTACCGGGCAATGGGGATATCGTAGTCAGTAATAAGTGAGGAGAGATGAGTTCATTTGTGAGAGGCTC
TGACCAGTGGAATCAGAGGAAGGGAGTTCCCCTGGGTGGGCCAGGTTCAAAGACATTTTGGAAGTAGAATCTGCAGAACATGATGATCTT
TTGGAAACAGGGCAGGGACGTGAATGAGCACGTAATGTCCCCATGGGTTTGTCTTTCCGAAGGTTTAAAATCCTCAAGAATAAGGAACAT

>45736_45736_3_LMBR1-LINC01006_LMBR1_chr7_156589083_ENST00000540390_LINC01006_chr7_156398458_ENST00000447933_length(amino acids)=180AA_BP=1
MSEPLRRADDGVAEHADAGGAAAGMKEDGRAGRGVGAGAALPQPSAGVHDEQEDEDAIVNRISLFLSTFTLAVSAGAVLLLPFSIISNEI
LLSFPQNYYIQWLNGSLIHGLWNLASLFSNLCLFVLMPFAFFFLESEGFAGLKKALLVRSHHVPWPPVSSALHDISRGTSLLGSRPHGCG

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for LMBR1-LINC01006

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for LMBR1-LINC01006

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for LMBR1-LINC01006

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source