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	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:LMNA-PPP1R18 (FusionGDB2 ID:45794)

Fusion Gene Summary for LMNA-PPP1R18

Fusion gene summary

Fusion gene information	Fusion gene name: LMNA-PPP1R18
	Fusion gene ID: 45794
		Hgene	Tgene
	Gene symbol	LMNA	PPP1R18
	Gene ID	4000	170954
	Gene name	lamin A/C	protein phosphatase 1 regulatory subunit 18
	Synonyms	CDCD1\|CDDC\|CMD1A\|CMT2B1\|EMD2\|FPL\|FPLD\|FPLD2\|HGPS\|IDC\|LDP1\|LFP\|LGMD1B\|LMN1\|LMNC\|LMNL1\|MADA\|PRO1	HKMT1098\|KIAA1949
	Cytomap	1q22	6p21.33
	Type of gene	protein-coding	protein-coding
	Description	lamin70 kDa laminepididymis secretory sperm binding proteinlamin A/C-like 1mandibuloacral dysplasia type Aprelamin-A/Crenal carcinoma antigen NY-REN-32	phostensinprotein phosphatase 1 F-actin cytoskeleton targeting subunit
	Modification date	20200329	20200313
	UniProtAcc	P02545	Q6NYC8
	Ensembl transtripts involved in fusion gene	ENST00000347559, ENST00000361308, ENST00000368297, ENST00000368299, ENST00000368300, ENST00000368301, ENST00000392353, ENST00000448611, ENST00000473598, ENST00000496738,	ENST00000274853, ENST00000399199, ENST00000488324, ENST00000383573, ENST00000400554, ENST00000412189, ENST00000435006, ENST00000435929, ENST00000437121, ENST00000438815, ENST00000438945, ENST00000443517, ENST00000444206, ENST00000449705, ENST00000451544, ENST00000455935, ENST00000465704, ENST00000472334, ENST00000487859, ENST00000491628, ENST00000492746, ENST00000493833, ENST00000498031, ENST00000548255, ENST00000550073, ENST00000551034, ENST00000551049, ENST00000551784, ENST00000552716,
Fusion gene scores	* DoF score	16 X 16 X 9=2304	7 X 8 X 5=280
	# samples	21	9
	** MAII score	log2(21/2304*10)=-3.45567948377619 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0	log2(9/280*10)=-1.63742992061529 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0
Context	PubMed: LMNA [Title/Abstract] AND PPP1R18 [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	LMNA(156076614)-PPP1R18(30647166), # samples:1
Anticipated loss of major functional domain due to fusion event.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	LMNA	GO:0090343	positive regulation of cell aging	20458013

Fusion gene breakpoints across LMNA (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across PPP1R18 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-CD-8531-01A	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-

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Fusion Gene ORF analysis for LMNA-PPP1R18

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
intron-5UTR	ENST00000347559	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000347559	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000347559	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000361308	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000361308	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000361308	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368297	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368297	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368297	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368299	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368299	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368299	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368300	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368300	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368300	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368301	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368301	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000368301	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000392353	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000392353	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000392353	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000448611	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000448611	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000448611	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000473598	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000473598	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000473598	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000496738	ENST00000274853	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000496738	ENST00000399199	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-5UTR	ENST00000496738	ENST00000488324	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000347559	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000361308	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368297	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368299	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368300	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000368301	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000392353	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000448611	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000473598	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000383573	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000400554	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000412189	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000435006	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000435929	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000437121	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000438815	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000438945	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000443517	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000444206	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000449705	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000451544	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000455935	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000465704	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000472334	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000487859	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000491628	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000492746	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000493833	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000498031	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000548255	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000550073	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000551034	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000551049	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000551784	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-
intron-intron	ENST00000496738	ENST00000552716	LMNA	chr1	156076614	+	PPP1R18	chr6	30647166	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

Seq length
(transcript)

BP loci
(transcript)

Predicted start
(transcript)

Predicted stop
(transcript)

Seq length
(amino acids)

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst

Tenst

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

No-coding score

Coding score

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Fusion Genomic Features for LMNA-PPP1R18

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LMNA-PPP1R18

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/:156076614/:30647166)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
LMNA P02545	PPP1R18 Q6NYC8
FUNCTION: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin A and C are present in equal amounts in the lamina of mammals. Recruited by DNA repair proteins XRCC4 and IFFO1 to the DNA double-strand breaks (DSBs) to prevent chromosome translocation by immobilizing broken DNA ends (PubMed:31548606). Plays an important role in nuclear assembly, chromatin organization, nuclear membrane and telomere dynamics. Required for normal development of peripheral nervous system and skeletal muscle and for muscle satellite cell proliferation (PubMed:10080180, PubMed:22431096, PubMed:10814726, PubMed:11799477, PubMed:18551513). Required for osteoblastogenesis and bone formation (PubMed:12075506, PubMed:15317753, PubMed:18611980). Also prevents fat infiltration of muscle and bone marrow, helping to maintain the volume and strength of skeletal muscle and bone (PubMed:10587585). Required for cardiac homeostasis (PubMed:10580070, PubMed:12927431, PubMed:18611980, PubMed:23666920). {ECO:0000269\|PubMed:10080180, ECO:0000269\|PubMed:10580070, ECO:0000269\|PubMed:10587585, ECO:0000269\|PubMed:10814726, ECO:0000269\|PubMed:11799477, ECO:0000269\|PubMed:12075506, ECO:0000269\|PubMed:12927431, ECO:0000269\|PubMed:15317753, ECO:0000269\|PubMed:18551513, ECO:0000269\|PubMed:18611980, ECO:0000269\|PubMed:22431096, ECO:0000269\|PubMed:23666920, ECO:0000269\|PubMed:31548606}.; FUNCTION: Prelamin-A/C can accelerate smooth muscle cell senescence. It acts to disrupt mitosis and induce DNA damage in vascular smooth muscle cells (VSMCs), leading to mitotic failure, genomic instability, and premature senescence.	FUNCTION: [Isoform 1]: May target protein phosphatase 1 to F-actin cytoskeleton. {ECO:0000269\|PubMed:24434620}.; FUNCTION: [Isoform 4]: May target protein phosphatase 1 to F-actin cytoskeleton. {ECO:0000269\|PubMed:17374523}.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

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Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

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Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

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Fusion Gene Sequence for LMNA-PPP1R18

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

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Fusion Gene PPI Analysis for LMNA-PPP1R18

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

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Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

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Related Drugs for LMNA-PPP1R18

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

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Related Diseases for LMNA-PPP1R18

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source