Home

Download

Statistics

Examples

Help

Contact

	Fusion Gene Summary
	Fusion Gene ORF analysis
	Fusion Genomic Features
	Fusion Protein Features
	Fusion Gene Sequence
	Fusion Gene PPI analysis
	Related Drugs
	Related Diseases

Fusion gene:LMTK3-DBP (FusionGDB2 ID:45852)

Fusion Gene Summary for LMTK3-DBP

Fusion gene summary

Fusion gene information	Fusion gene name: LMTK3-DBP
	Fusion gene ID: 45852
		Hgene	Tgene
	Gene symbol	LMTK3	DBP
	Gene ID	114783	3295
	Gene name	lemur tyrosine kinase 3	hydroxysteroid 17-beta dehydrogenase 4
	Synonyms	LMR3\|PPP1R101\|TYKLM3	DBP\|MFE-2\|MPF-2\|PRLTS1\|SDR8C1
	Cytomap	19q13.33	5q23.1
	Type of gene	protein-coding	protein-coding
	Description	serine/threonine-protein kinase LMTK3protein phosphatase 1, regulatory subunit 101	peroxisomal multifunctional enzyme type 217-beta-HSD 417-beta-HSD IV17-beta-hydroxysteroid dehydrogenase 417beta-estradiol dehydrogenase type IV3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydrataseD-3-hydroxyacyl-CoA dehydratase
	Modification date	20200313	20200327
	UniProtAcc	Q96Q04	Q10586
	Ensembl transtripts involved in fusion gene	ENST00000270238, ENST00000600059,	ENST00000601104, ENST00000593500, ENST00000222122, ENST00000599385,
Fusion gene scores	* DoF score	3 X 3 X 3=27	3 X 1 X 3=9
	# samples	3	3
	** MAII score	log2(3/27*10)=0.15200309344505 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0	log2(3/9*10)=1.73696559416621 effective Gene in Pan-Cancer Fusion Genes (eGinPCFGs). DoF>8 and MAII>0
Context	PubMed: LMTK3 [Title/Abstract] AND DBP [Title/Abstract] AND fusion [Title/Abstract]
Most frequent breakpoint	LMTK3(48994365)-DBP(49134309), # samples:3
Anticipated loss of major functional domain due to fusion event.	LMTK3-DBP seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF. LMTK3-DBP seems lost the major protein functional domain in Hgene partner, which is a IUPHAR drug target due to the frame-shifted ORF. LMTK3-DBP seems lost the major protein functional domain in Hgene partner, which is a kinase due to the frame-shifted ORF. LMTK3-DBP seems lost the major protein functional domain in Tgene partner, which is a transcription factor due to the frame-shifted ORF.

* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez

Partner	Gene	GO ID	GO term	PubMed ID
Hgene	LMTK3	GO:0010923	negative regulation of phosphatase activity	19389623
Tgene	DBP	GO:0006635	fatty acid beta-oxidation	10400999
Tgene	DBP	GO:0008209	androgen metabolic process	7487879
Tgene	DBP	GO:0008210	estrogen metabolic process	7487879
Tgene	DBP	GO:0036111	very long-chain fatty-acyl-CoA metabolic process	9482850
Tgene	DBP	GO:0036112	medium-chain fatty-acyl-CoA metabolic process	9089413

Fusion gene breakpoints across LMTK3 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene breakpoints across DBP (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.

Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

Source	Disease	Sample	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
ChimerDB4	STAD	TCGA-CD-8527-01A	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-

Top

Fusion Gene ORF analysis for LMTK3-DBP

Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.

ORF	Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand
5CDS-intron	ENST00000270238	ENST00000601104	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-
5CDS-intron	ENST00000600059	ENST00000601104	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-
Frame-shift	ENST00000270238	ENST00000593500	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-
Frame-shift	ENST00000600059	ENST00000593500	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-
In-frame	ENST00000270238	ENST00000222122	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-
In-frame	ENST00000270238	ENST00000599385	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-
In-frame	ENST00000600059	ENST00000222122	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-
In-frame	ENST00000600059	ENST00000599385	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-

ORFfinder result based on the fusion transcript sequence of in-frame fusion genes.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	Seq length (transcript)	BP loci (transcript)	Predicted start (transcript)	Predicted stop (transcript)	Seq length (amino acids)
ENST00000600059	LMTK3	chr19	48994365	-	ENST00000222122	DBP	chr19	49134309	-	5617	4594	3	4598	1531
ENST00000600059	LMTK3	chr19	48994365	-	ENST00000599385	DBP	chr19	49134309	-	4962	4594	3	4598	1531
ENST00000270238	LMTK3	chr19	48994365	-	ENST00000222122	DBP	chr19	49134309	-	5476	4453	0	4457	1485
ENST00000270238	LMTK3	chr19	48994365	-	ENST00000599385	DBP	chr19	49134309	-	4821	4453	0	4457	1485

DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.

Henst	Tenst	Hgene	Hchr	Hbp	Hstrand	Tgene	Tchr	Tbp	Tstrand	No-coding score	Coding score
ENST00000600059	ENST00000222122	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-	0.004140483	0.99585956
ENST00000600059	ENST00000599385	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-	0.004582542	0.9954175
ENST00000270238	ENST00000222122	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-	0.003343333	0.99665666
ENST00000270238	ENST00000599385	LMTK3	chr19	48994365	-	DBP	chr19	49134309	-	0.003674081	0.9963259

Top

Fusion Genomic Features for LMTK3-DBP

FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.

Hgene

Hchr

Hbp

Hstrand

Tgene

Tchr

Tbp

Tstrand

1-p

p (fusion gene breakpoint)

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.

Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

Top

Fusion Protein Features for LMTK3-DBP

Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr19:48994365/chr19:49134309)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.

Main function of each fusion partner protein. (from UniProt)

Hgene	Tgene
LMTK3 Q96Q04	DBP Q10586
FUNCTION: Protein kinase which phosphorylates ESR1 (in vitro) and protects it against proteasomal degradation. May also regulate ESR1 levels indirectly via a PKC-AKT-FOXO3 pathway where it decreases the activity of PKC and the phosphorylation of AKT, thereby increasing binding of transcriptional activator FOXO3 to the ESR1 promoter and increasing ESR1 transcription (PubMed:21602804). Involved in endocytic trafficking of N-methyl-D-aspartate receptors (NMDAR) in neurons (By similarity). {ECO:0000250\|UniProtKB:Q5XJV6, ECO:0000269\|PubMed:21602804}.	FUNCTION: This transcriptional activator recognizes and binds to the sequence 5'-RTTAYGTAAY-3' found in the promoter of genes such as albumin, CYP2A4 and CYP2A5. It is not essential for circadian rhythm generation, but modulates important clock output genes. May be a direct target for regulation by the circadian pacemaker component clock. May affect circadian period and sleep regulation.

Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at
download page

* Minus value of BPloci means that the break pointn is located before the CDS.

- In-frame and retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Hgene

LMTK3

chr19:48994365

chr19:49134309

ENST00000600059

416_1457

1455

1461.0

Compositional bias

Note=Pro-rich

Hgene

LMTK3

chr19:48994365

chr19:49134309

ENST00000600059

133_411

1455

1461.0

Domain

Protein kinase

Hgene

LMTK3

chr19:48994365

chr19:49134309

ENST00000600059

139_147

1455

1461.0

Nucleotide binding

ATP

Hgene

LMTK3

chr19:48994365

chr19:49134309

ENST00000600059

40_60

1455

1461.0

Transmembrane

Helical

Tgene

DBP

chr19:48994365

chr19:49134309

ENST00000222122

255_318

254

326.0

Domain

bZIP

Tgene

DBP

chr19:48994365

chr19:49134309

ENST00000222122

257_279

254

326.0

Region

Basic motif

Tgene

DBP

chr19:48994365

chr19:49134309

ENST00000222122

283_297

254

326.0

Region

Leucine-zipper

- In-frame and not-retained protein feature among the 13 regional features.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Protein feature

Protein feature note

Tgene

DBP

chr19:48994365

chr19:49134309

ENST00000222122

129_135

254

326.0

Compositional bias

Note=Poly-Pro

Tgene

DBP

chr19:48994365

chr19:49134309

ENST00000222122

188_239

254

326.0

Compositional bias

Note=Pro-rich (proline/acidic region (PAR))

Top

Fusion Gene Sequence for LMTK3-DBP

For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.

>45852_45852_1_LMTK3-DBP_LMTK3_chr19_48994365_ENST00000270238_DBP_chr19_49134309_ENST00000222122_length(transcript)=5476nt_BP=4453nt
ATGAGGCAAGTGCTGTGGTTGTGTAATGTCTGCGTAACCGCACGGGAAACCCGCCACCACCTCCACCTCCCTGCCATCCTCGACAAGATG
CCTGCCCCCGGCGCCCTCATCCTCCTTGCGGCCGTCTCCGCCTCCGGCTGCCTGGCGTCCCCGGCCCACCCCGATGGATTCGCCCTGGGC
CGGGCTCCTCTGGCTCCTCCCTACGCTGTGGTCCTCATTTCCTGCTCCGGCCTGCTGGCCTTCATCTTCCTCCTCCTCACCTGTCTGTGC
TGCAAACGGGGCGATGTCGGCTTCAAGGAATTTGAGAACCCTGAAGGGGAGGACTGCTCCGGGGAGTACACTCCCCCTGCGGAGGAGACC
TCCTCCTCACAGTCGCTGCCTGATGTCTACATTCTCCCGCTGGCTGAGGTCTCCCTGCCAATGCCTGCCCCGCAGCCTTCACACTCAGAC
ATGACCACCCCCCTGGGCCTTAGCCGGCAGCACCTGAGCTACCTGCAGGAGATTGGGAGTGGCTGGTTTGGGAAGGTGATCCTGGGAGAG
ATTTTCTCCGACTACACCCCCGCCCAGGTGGTGGTGAAGGAGCTCCGAGCCAGCGCGGGGCCCCTGGAGCAACGCAAGTTCATCTCGGAA
GCACAGCCGTACAGGAGCCTGCAGCACCCCAATGTCCTCCAGTGCCTGGGTCTGTGCGTGGAGACGCTGCCGTTTCTGCTGATTATGGAG
TTCTGTCAACTGGGGGACCTGAAGCGTTACCTCCGAGCCCAGCGGCCCCCCGAGGGCCTGTCCCCTGAGCTACCCCCTCGAGACCTGCGG
ACGCTGCAGAGGATGGGCCTGGAGATCGCCCGCGGGCTGGCGCACCTGCATTCCCACAACTACGTGCACAGCGACCTGGCCCTGCGCAAC
TGCCTGCTGACCTCTGACCTGACCGTGCGCATCGGAGACTACGGGCTGGCCCACAGCAACTACAAGGAGGACTACTACCTGACCCCAGAG
CGCCTGTGGATCCCACTGCGCTGGGCGGCGCCCGAGCTCCTCGGGGAGCTCCACGGGACCTTCATGGTGGTGGACCAGAGCCGCGAGAGC
AACATCTGGTCCCTGGGGGTGACCCTGTGGGAGCTGTTTGAGTTTGGGGCCCAGCCCTACCGCCACCTGTCAGACGAGGAGGTCCTCGCC
TTCGTGGTCCGCCAGCAGCATGTGAAGCTGGCCCGGCCGAGGCTCAAGCTGCCTTACGCGGACTACTGGTATGACATTCTTCAGTCCTGC
TGGCGGCCACCTGCCCAGCGCCCTTCAGCCTCTGATCTCCAATTGCAGCTCACCTACTTGCTCTCCGAGCGGCCTCCCCGGCCCCCACCG
CCGCCACCCCCACCCCGAGACGGTCCCTTCCCCTGGCCCTGGCCCCCTGCACACAGTGCGCCCCGCCCGGGGACCCTCTCCTCACCGTTC
CCCCTACTGGATGGCTTCCCTGGAGCCGACCCCGACGATGTGCTCACGGTCACCGAGAGTAGCCGCGGCCTCAACCTCGAGTGCCTGTGG
GAGAAGGCCCGGCGTGGGGCCGGCCGGGGTGGGGGGGCACCTGCCTGGCAGCCGGCGTCGGCCCCCCCGGCCCCCCACGCCAACCCCTCC
AACCCTTTCTACGAGGCGCTGTCCACGCCCAGCGTGCTGCCTGTCATCAGCGCCCGCAGCCCCTCCGTGAGCAGCGAGTACTACATCCGC
TTGGAGGAGCACGGCTCCCCTCCTGAGCCCCTCTTCCCCAACGACTGGGACCCCCTGGACCCAGGAGTGCCCGCCCCTCAGGCCCCCCAG
GCCCCCTCCGAGGTCCCCCAGCTGGTGTCCGAGACCTGGGCCTCCCCCCTCTTCCCTGCGCCCCGGCCCTTCCCAGCCCAGTCCTCAGCG
TCAGGCAGCTTCCTGCTGAGCGGCTGGGACCCCGAGGGCCGGGGCGCCGGGGAGACCCTGGCGGGAGACCCTGCCGAGGTCTTGGGGGAG
CGGGGGACCGCCCCGTGGGTGGAAGAAGAAGAGGAGGAGGAGGAGGGCAGCTCCCCAGGGGAAGACAGCAGCAGCCTTGGAGGTGGCCCA
AGCCGCCGGGGTCCCCTACCCTGTCCCCTGTGCAGCCGCGAGGGGGCCTGCTCCTGCCTGCCACTGGAGCGGGGGGACGCCGTAGCAGGC
TGGGGAGGCCACCCTGCTCTTGGCTGCCCCCACCCCCCCGAGGACGACTCCTCGCTGCGGGCAGAGCGGGGCTCCCTGGCCGACTTGCCC
ATGGCCCCCCCCGCCTCGGCCCCCCCCGAGTTTCTGGACCCCCTCATGGGGGCGGCGGCGCCCCAGTACCCCGGGCGGGGGCCACCTCCC
GCTCCCCCCCCCCCGCCGCCACCTCCTCGGGCCCCCGCGGACCCGGCCGCGTCCCCCGACCCCCCTTCGGCCGTGGCCAGTCCCGGTTCA
GGCCTCTCGTCGCCGGGCCCCAAGCCGGGGGACAGCGGCTACGAGACCGAGACCCCTTTTTCCCCAGAGGGAGCCTTCCCAGGTGGGGGG
GCGGCCGAGGAGGAAGGGGTCCCTCGGCCGCGGGCTCCCCCCGAGCCACCCGACCCAGGAGCGCCCCGGCCACCTCCAGACCCGGGTCCG
CTCCCACTCCCGGGGCCCCGGGAGAAGCCGACCTTCGTGGTTCAAGTGAGCACGGAACAGCTGCTGATGTCCCTGCGGGAGGATGTGACA
AGGAACCTCCTGGGGGAGAAGGGGGCGACAGCCCGGGAGACAGGACCCAGGAAGGCGGGGAGAGGCCCCGGGAACAGAGAGAAAGTCCCG
GGCCTGAACAGGGACCCGACAGTCCTGGGCAACGGGAAACAAGCCCCAAGCCTGAGCCTCCCAGTGAACGGGGTGACAGTGCTGGAGAAC
GGGGACCAGAGAGCCCCAGGCATCGAGGAGAAGGCGGCGGAGAATGGGGCCCTGGGGTCCCCCGAGAGAGAAGAGAAAGTGCTGGAGAAT
GGGGAGCTGACACCCCCAAGGAGGGAGGAGAAAGCGCTGGAGAATGGGGAGCTGAGGTCCCCAGAGGCCGGGGAGAAGGTGCTGGTGAAT
GGGGGCCTGACACCCCCAAAGAGCGAGGACAAGGTGTCAGAGAATGGGGGCCTGAGATTCCCCAGGAACACGGAGAGGCCACCAGAGACT
GGGCCTTGGAGAGCCCCAGGGCCCTGGGAGAAGACGCCCGAGAGTTGGGGTCCAGCCCCCACGATCGGGGAGCCAGCCCCAGAGACCTCT
CTGGAGAGAGCCCCTGCACCCAGCGCAGTGGTCTCCTCCCGGAACGGCGGGGAGACAGCCCCTGGCCCCCTTGGCCCAGCCCCCAAGAAC
GGGACGCTGGAACCCGGGACCGAGAGGAGAGCCCCCGAGACTGGGGGGGCGCCGAGAGCCCCAGGGGCTGGGAGGCTGGACCTCGGGAGT
GGGGGCCGAGCCCCAGTGGGCACGGGGACGGCCCCCGGCGGCGGCCCCGGAAGCGGCGTGGACGCAAAGGCCGGATGGGTAGACAACACG
AGGCCGCAGCCACCGCCGCCACCGCTGCCACCGCCACCGGAGGCACAGCCGAGGAGGCTGGAGCCAGCGCCCCCGAGAGCCAGGCCGGAG
GTGGCCCCCGAGGGAGAGCCCGGGGCCCCAGACAGCAGGGCCGGCGGAGACACGGCACTCAGCGGAGACGGGGACCCCCCCAAGCCCGAG
AGGAAGGGCCCCGAGATGCCACGACTATTCTTGGACTTGGGACCCCCTCAGGGGAACAGCGAGCAGATCAAAGCCAGGCTCTCCCGGCTC
TCGCTGGCGCTGCCGCCGCTCACGCTCACGCCATTCCCGGGGCCGGGCCCGCGGCGGCCCCCGTGGGAGGGCGCGGACGCCGGGGCGGCT
GGCGGGGAGGCCGGCGGGGCGGGAGCGCCGGGGCCGGCGGAGGAGGACGGGGAGGACGAGGACGAGGACGAGGAGGAGGACGAGGAGGCG
GCGGCGCCGGGCGCGGCGGCGGGGCCGCGGGGCCCCGGGAGGGCGCGAGCAGCCCCGGTGCCCGTCGTGGTGAGCAGCGCCGACGCGGAC
GCGGCCCGCCCGCTGCGGGGGCTGCTCAAGTCTCCGCGCGGGGCCGACGAGCCAGAGGACAGCGAGCTGGAGAGGAAGCGCAAGATGGTC
TCCTTCCACGGGGACGTGACCGTCTACCTCTTCGACCAGGAGACGCCAACCAACGAGCTGAGCGTCCAGGCCCCCCCCGAGGGGGACACG
GACCCGTCAACGCCTCCAGCGCCCCCGACACCTCCCCACCCCGCCACCCCCGGAGATGGGTTTCCCAGCAACGACAGCGGCTTTGGAGGC
AGTTTCGAGTGGGCGGAGGATTTCCCCCTCCTCCCCCCTCCAGGCCCCCCGCTGTGCTTCTCCCGCTTCTCCGTCTCGCCTGCGCTGGAG
ACCCCGGGGCCACCCGCCCGGGCCCCCGACGCCCGGCCCGCAGGATGAGAAATACTGGAGCCGGCGGTACAAGAACAACGAGGCAGCCAA
GCGGTCCCGTGACGCCCGGCGGCTCAAGGAGAACCAGATATCGGTGCGGGCGGCCTTCCTGGAGAAGGAGAACGCCCTGCTGCGGCAGGA
AGTTGTGGCCGTGCGCCAGGAGCTGTCCCACTACCGCGCCGTGCTGTCCCGATACCAGGCCCAGCACGGGGCCCTGTGAGGCTGCCCCAC
ATCCCCACCTGGCGGAGCTCTCCTCCGCCTTGCTGAGACTTACGCCCTGTTCCCTTCCTGCCCTGTGGCCCACGGGCCGGCCAGCTGGGT
GCCCCAGGGACGTGATAATGCAGATAAATACATTTATATTTTTAAGAAAAAGCGAGCCTCCCCCCTCCCTTGCGGGGGCGGGGAGGGTTC
TCTGTGTGTGTCCCCGGCACGTCAGGGACCCTATCCTCCCACCGCCTCCGTTAACACGATCCTGAATAAATCTTGAGAACCCCAGAGCCA
GCTGTTGTGGAAGAAGAGGGCAGCTCCCTGGCATACTGGCTGCAGCCCGTGGGCAGCTCCGGGCTGTCGTCCATAGAGGGCAGGCGCTGC
TGGAAGTGCTGGAGTCTGAGTCCTCCCGCGGGCTGTCGGATGGAGGAAGGGCAGAAGGTCTGAGAGGAATGAAGCGACTGCCTTTATTGC
ATAGACCTTTTCAATTGCTTTTTAGATTGGGGACGGAGGACGCGCATGAGACGAACAGGGGATATGAATTTCCCCGCCCCCACCCGCGGG
GAGAGGAACATTAGTGCAAATCCTAGCGCCGGCCCCGGGGAACCTGCCCCTCCTGGGCTGATTGGCCAGCTAAATGGAGGCACCGGAGTG
GATGGGGCGAGGCTGCGGGCCCTGACCGGCCGACTCACTGAGGCCTACCCCAGCCAGTACATTCCAGGTCCTGTCATTGGGCGACGCGTA

>45852_45852_1_LMTK3-DBP_LMTK3_chr19_48994365_ENST00000270238_DBP_chr19_49134309_ENST00000222122_length(amino acids)=1485AA_BP=773
MRQVLWLCNVCVTARETRHHLHLPAILDKMPAPGALILLAAVSASGCLASPAHPDGFALGRAPLAPPYAVVLISCSGLLAFIFLLLTCLC
CKRGDVGFKEFENPEGEDCSGEYTPPAEETSSSQSLPDVYILPLAEVSLPMPAPQPSHSDMTTPLGLSRQHLSYLQEIGSGWFGKVILGE
IFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPRDLR
TLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRES
NIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPP
PPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPS
NPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSA
SGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAG
WGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGS
GLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVT
RNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLEN
GELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETS
LERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNT
RPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRL
SLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADAD
AARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGG

--------------------------------------------------------------
>45852_45852_2_LMTK3-DBP_LMTK3_chr19_48994365_ENST00000270238_DBP_chr19_49134309_ENST00000599385_length(transcript)=4821nt_BP=4453nt
ATGAGGCAAGTGCTGTGGTTGTGTAATGTCTGCGTAACCGCACGGGAAACCCGCCACCACCTCCACCTCCCTGCCATCCTCGACAAGATG
CCTGCCCCCGGCGCCCTCATCCTCCTTGCGGCCGTCTCCGCCTCCGGCTGCCTGGCGTCCCCGGCCCACCCCGATGGATTCGCCCTGGGC
CGGGCTCCTCTGGCTCCTCCCTACGCTGTGGTCCTCATTTCCTGCTCCGGCCTGCTGGCCTTCATCTTCCTCCTCCTCACCTGTCTGTGC
TGCAAACGGGGCGATGTCGGCTTCAAGGAATTTGAGAACCCTGAAGGGGAGGACTGCTCCGGGGAGTACACTCCCCCTGCGGAGGAGACC
TCCTCCTCACAGTCGCTGCCTGATGTCTACATTCTCCCGCTGGCTGAGGTCTCCCTGCCAATGCCTGCCCCGCAGCCTTCACACTCAGAC
ATGACCACCCCCCTGGGCCTTAGCCGGCAGCACCTGAGCTACCTGCAGGAGATTGGGAGTGGCTGGTTTGGGAAGGTGATCCTGGGAGAG
ATTTTCTCCGACTACACCCCCGCCCAGGTGGTGGTGAAGGAGCTCCGAGCCAGCGCGGGGCCCCTGGAGCAACGCAAGTTCATCTCGGAA
GCACAGCCGTACAGGAGCCTGCAGCACCCCAATGTCCTCCAGTGCCTGGGTCTGTGCGTGGAGACGCTGCCGTTTCTGCTGATTATGGAG
TTCTGTCAACTGGGGGACCTGAAGCGTTACCTCCGAGCCCAGCGGCCCCCCGAGGGCCTGTCCCCTGAGCTACCCCCTCGAGACCTGCGG
ACGCTGCAGAGGATGGGCCTGGAGATCGCCCGCGGGCTGGCGCACCTGCATTCCCACAACTACGTGCACAGCGACCTGGCCCTGCGCAAC
TGCCTGCTGACCTCTGACCTGACCGTGCGCATCGGAGACTACGGGCTGGCCCACAGCAACTACAAGGAGGACTACTACCTGACCCCAGAG
CGCCTGTGGATCCCACTGCGCTGGGCGGCGCCCGAGCTCCTCGGGGAGCTCCACGGGACCTTCATGGTGGTGGACCAGAGCCGCGAGAGC
AACATCTGGTCCCTGGGGGTGACCCTGTGGGAGCTGTTTGAGTTTGGGGCCCAGCCCTACCGCCACCTGTCAGACGAGGAGGTCCTCGCC
TTCGTGGTCCGCCAGCAGCATGTGAAGCTGGCCCGGCCGAGGCTCAAGCTGCCTTACGCGGACTACTGGTATGACATTCTTCAGTCCTGC
TGGCGGCCACCTGCCCAGCGCCCTTCAGCCTCTGATCTCCAATTGCAGCTCACCTACTTGCTCTCCGAGCGGCCTCCCCGGCCCCCACCG
CCGCCACCCCCACCCCGAGACGGTCCCTTCCCCTGGCCCTGGCCCCCTGCACACAGTGCGCCCCGCCCGGGGACCCTCTCCTCACCGTTC
CCCCTACTGGATGGCTTCCCTGGAGCCGACCCCGACGATGTGCTCACGGTCACCGAGAGTAGCCGCGGCCTCAACCTCGAGTGCCTGTGG
GAGAAGGCCCGGCGTGGGGCCGGCCGGGGTGGGGGGGCACCTGCCTGGCAGCCGGCGTCGGCCCCCCCGGCCCCCCACGCCAACCCCTCC
AACCCTTTCTACGAGGCGCTGTCCACGCCCAGCGTGCTGCCTGTCATCAGCGCCCGCAGCCCCTCCGTGAGCAGCGAGTACTACATCCGC
TTGGAGGAGCACGGCTCCCCTCCTGAGCCCCTCTTCCCCAACGACTGGGACCCCCTGGACCCAGGAGTGCCCGCCCCTCAGGCCCCCCAG
GCCCCCTCCGAGGTCCCCCAGCTGGTGTCCGAGACCTGGGCCTCCCCCCTCTTCCCTGCGCCCCGGCCCTTCCCAGCCCAGTCCTCAGCG
TCAGGCAGCTTCCTGCTGAGCGGCTGGGACCCCGAGGGCCGGGGCGCCGGGGAGACCCTGGCGGGAGACCCTGCCGAGGTCTTGGGGGAG
CGGGGGACCGCCCCGTGGGTGGAAGAAGAAGAGGAGGAGGAGGAGGGCAGCTCCCCAGGGGAAGACAGCAGCAGCCTTGGAGGTGGCCCA
AGCCGCCGGGGTCCCCTACCCTGTCCCCTGTGCAGCCGCGAGGGGGCCTGCTCCTGCCTGCCACTGGAGCGGGGGGACGCCGTAGCAGGC
TGGGGAGGCCACCCTGCTCTTGGCTGCCCCCACCCCCCCGAGGACGACTCCTCGCTGCGGGCAGAGCGGGGCTCCCTGGCCGACTTGCCC
ATGGCCCCCCCCGCCTCGGCCCCCCCCGAGTTTCTGGACCCCCTCATGGGGGCGGCGGCGCCCCAGTACCCCGGGCGGGGGCCACCTCCC
GCTCCCCCCCCCCCGCCGCCACCTCCTCGGGCCCCCGCGGACCCGGCCGCGTCCCCCGACCCCCCTTCGGCCGTGGCCAGTCCCGGTTCA
GGCCTCTCGTCGCCGGGCCCCAAGCCGGGGGACAGCGGCTACGAGACCGAGACCCCTTTTTCCCCAGAGGGAGCCTTCCCAGGTGGGGGG
GCGGCCGAGGAGGAAGGGGTCCCTCGGCCGCGGGCTCCCCCCGAGCCACCCGACCCAGGAGCGCCCCGGCCACCTCCAGACCCGGGTCCG
CTCCCACTCCCGGGGCCCCGGGAGAAGCCGACCTTCGTGGTTCAAGTGAGCACGGAACAGCTGCTGATGTCCCTGCGGGAGGATGTGACA
AGGAACCTCCTGGGGGAGAAGGGGGCGACAGCCCGGGAGACAGGACCCAGGAAGGCGGGGAGAGGCCCCGGGAACAGAGAGAAAGTCCCG
GGCCTGAACAGGGACCCGACAGTCCTGGGCAACGGGAAACAAGCCCCAAGCCTGAGCCTCCCAGTGAACGGGGTGACAGTGCTGGAGAAC
GGGGACCAGAGAGCCCCAGGCATCGAGGAGAAGGCGGCGGAGAATGGGGCCCTGGGGTCCCCCGAGAGAGAAGAGAAAGTGCTGGAGAAT
GGGGAGCTGACACCCCCAAGGAGGGAGGAGAAAGCGCTGGAGAATGGGGAGCTGAGGTCCCCAGAGGCCGGGGAGAAGGTGCTGGTGAAT
GGGGGCCTGACACCCCCAAAGAGCGAGGACAAGGTGTCAGAGAATGGGGGCCTGAGATTCCCCAGGAACACGGAGAGGCCACCAGAGACT
GGGCCTTGGAGAGCCCCAGGGCCCTGGGAGAAGACGCCCGAGAGTTGGGGTCCAGCCCCCACGATCGGGGAGCCAGCCCCAGAGACCTCT
CTGGAGAGAGCCCCTGCACCCAGCGCAGTGGTCTCCTCCCGGAACGGCGGGGAGACAGCCCCTGGCCCCCTTGGCCCAGCCCCCAAGAAC
GGGACGCTGGAACCCGGGACCGAGAGGAGAGCCCCCGAGACTGGGGGGGCGCCGAGAGCCCCAGGGGCTGGGAGGCTGGACCTCGGGAGT
GGGGGCCGAGCCCCAGTGGGCACGGGGACGGCCCCCGGCGGCGGCCCCGGAAGCGGCGTGGACGCAAAGGCCGGATGGGTAGACAACACG
AGGCCGCAGCCACCGCCGCCACCGCTGCCACCGCCACCGGAGGCACAGCCGAGGAGGCTGGAGCCAGCGCCCCCGAGAGCCAGGCCGGAG
GTGGCCCCCGAGGGAGAGCCCGGGGCCCCAGACAGCAGGGCCGGCGGAGACACGGCACTCAGCGGAGACGGGGACCCCCCCAAGCCCGAG
AGGAAGGGCCCCGAGATGCCACGACTATTCTTGGACTTGGGACCCCCTCAGGGGAACAGCGAGCAGATCAAAGCCAGGCTCTCCCGGCTC
TCGCTGGCGCTGCCGCCGCTCACGCTCACGCCATTCCCGGGGCCGGGCCCGCGGCGGCCCCCGTGGGAGGGCGCGGACGCCGGGGCGGCT
GGCGGGGAGGCCGGCGGGGCGGGAGCGCCGGGGCCGGCGGAGGAGGACGGGGAGGACGAGGACGAGGACGAGGAGGAGGACGAGGAGGCG
GCGGCGCCGGGCGCGGCGGCGGGGCCGCGGGGCCCCGGGAGGGCGCGAGCAGCCCCGGTGCCCGTCGTGGTGAGCAGCGCCGACGCGGAC
GCGGCCCGCCCGCTGCGGGGGCTGCTCAAGTCTCCGCGCGGGGCCGACGAGCCAGAGGACAGCGAGCTGGAGAGGAAGCGCAAGATGGTC
TCCTTCCACGGGGACGTGACCGTCTACCTCTTCGACCAGGAGACGCCAACCAACGAGCTGAGCGTCCAGGCCCCCCCCGAGGGGGACACG
GACCCGTCAACGCCTCCAGCGCCCCCGACACCTCCCCACCCCGCCACCCCCGGAGATGGGTTTCCCAGCAACGACAGCGGCTTTGGAGGC
AGTTTCGAGTGGGCGGAGGATTTCCCCCTCCTCCCCCCTCCAGGCCCCCCGCTGTGCTTCTCCCGCTTCTCCGTCTCGCCTGCGCTGGAG
ACCCCGGGGCCACCCGCCCGGGCCCCCGACGCCCGGCCCGCAGGATGAGAAATACTGGAGCCGGCGGTACAAGAACAACGAGGCAGCCAA
GCGGTCCCGTGACGCCCGGCGGCTCAAGGAGAACCAGATATCGGTGCGGGCGGCCTTCCTGGAGAAGGAGAACGCCCTGCTGCGGCAGGA
AGTTGTGGCCGTGCGCCAGGAGCTGTCCCACTACCGCGCCGTGCTGTCCCGATACCAGGCCCAGCACGGGGCCCTGTGAGGCTGCCCCAC
ATCCCCACCTGGCGGAGCTCTCCTCCGCCTTGCTGAGACTTACGCCCTGTTCCCTTCCTGCCCTGTGGCCCACGGGCCGGCCAGCTGGGT

>45852_45852_2_LMTK3-DBP_LMTK3_chr19_48994365_ENST00000270238_DBP_chr19_49134309_ENST00000599385_length(amino acids)=1485AA_BP=773
MRQVLWLCNVCVTARETRHHLHLPAILDKMPAPGALILLAAVSASGCLASPAHPDGFALGRAPLAPPYAVVLISCSGLLAFIFLLLTCLC
CKRGDVGFKEFENPEGEDCSGEYTPPAEETSSSQSLPDVYILPLAEVSLPMPAPQPSHSDMTTPLGLSRQHLSYLQEIGSGWFGKVILGE
IFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQCLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPRDLR
TLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDYGLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRES
NIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPRLKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPP
PPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDVLTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPS
NPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPNDWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSA
SGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEEEGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAG
WGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDPLMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGS
GLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPPEPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVT
RNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQAPSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLEN
GELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSENGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETS
LERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPETGGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNT
RPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRAGGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRL
SLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAEEDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADAD
AARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQETPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGG

--------------------------------------------------------------
>45852_45852_3_LMTK3-DBP_LMTK3_chr19_48994365_ENST00000600059_DBP_chr19_49134309_ENST00000222122_length(transcript)=5617nt_BP=4594nt
CCTCTGTCCGCCTCTCCATCCCTTCATCCGTCTGTCCCTTCAAAGAGGGGGAGGGGGGTACCTGAGCCAGCAAGCAGCCCCTCCCTCCCC
CTGTCCTGCGTCTCCTGCCCCTCTCCTGGGCCGGGAGGAGGCCAGGGTCGCGCGGGTCCCCATGGCTGGGGGCTGAGGGCCCGCCCCCCC
CTCCTCCCCAGCCGCCACCACCTCCACCTCCCTGCCATCCTCGACAAGATGCCTGCCCCCGGCGCCCTCATCCTCCTTGCGGCCGTCTCC
GCCTCCGGCTGCCTGGCGTCCCCGGCCCACCCCGATGGATTCGCCCTGGGCCGGGCTCCTCTGGCTCCTCCCTACGCTGTGGTCCTCATT
TCCTGCTCCGGCCTGCTGGCCTTCATCTTCCTCCTCCTCACCTGTCTGTGCTGCAAACGGGGCGATGTCGGCTTCAAGGAATTTGAGAAC
CCTGAAGGGGAGGACTGCTCCGGGGAGTACACTCCCCCTGCGGAGGAGACCTCCTCCTCACAGTCGCTGCCTGATGTCTACATTCTCCCG
CTGGCTGAGGTCTCCCTGCCAATGCCTGCCCCGCAGCCTTCACACTCAGACATGACCACCCCCCTGGGCCTTAGCCGGCAGCACCTGAGC
TACCTGCAGGAGATTGGGAGTGGCTGGTTTGGGAAGGTGATCCTGGGAGAGATTTTCTCCGACTACACCCCCGCCCAGGTGGTGGTGAAG
GAGCTCCGAGCCAGCGCGGGGCCCCTGGAGCAACGCAAGTTCATCTCGGAAGCACAGCCGTACAGGAGCCTGCAGCACCCCAATGTCCTC
CAGTGCCTGGGTCTGTGCGTGGAGACGCTGCCGTTTCTGCTGATTATGGAGTTCTGTCAACTGGGGGACCTGAAGCGTTACCTCCGAGCC
CAGCGGCCCCCCGAGGGCCTGTCCCCTGAGCTACCCCCTCGAGACCTGCGGACGCTGCAGAGGATGGGCCTGGAGATCGCCCGCGGGCTG
GCGCACCTGCATTCCCACAACTACGTGCACAGCGACCTGGCCCTGCGCAACTGCCTGCTGACCTCTGACCTGACCGTGCGCATCGGAGAC
TACGGGCTGGCCCACAGCAACTACAAGGAGGACTACTACCTGACCCCAGAGCGCCTGTGGATCCCACTGCGCTGGGCGGCGCCCGAGCTC
CTCGGGGAGCTCCACGGGACCTTCATGGTGGTGGACCAGAGCCGCGAGAGCAACATCTGGTCCCTGGGGGTGACCCTGTGGGAGCTGTTT
GAGTTTGGGGCCCAGCCCTACCGCCACCTGTCAGACGAGGAGGTCCTCGCCTTCGTGGTCCGCCAGCAGCATGTGAAGCTGGCCCGGCCG
AGGCTCAAGCTGCCTTACGCGGACTACTGGTATGACATTCTTCAGTCCTGCTGGCGGCCACCTGCCCAGCGCCCTTCAGCCTCTGATCTC
CAATTGCAGCTCACCTACTTGCTCTCCGAGCGGCCTCCCCGGCCCCCACCGCCGCCACCCCCACCCCGAGACGGTCCCTTCCCCTGGCCC
TGGCCCCCTGCACACAGTGCGCCCCGCCCGGGGACCCTCTCCTCACCGTTCCCCCTACTGGATGGCTTCCCTGGAGCCGACCCCGACGAT
GTGCTCACGGTCACCGAGAGTAGCCGCGGCCTCAACCTCGAGTGCCTGTGGGAGAAGGCCCGGCGTGGGGCCGGCCGGGGTGGGGGGGCA
CCTGCCTGGCAGCCGGCGTCGGCCCCCCCGGCCCCCCACGCCAACCCCTCCAACCCTTTCTACGAGGCGCTGTCCACGCCCAGCGTGCTG
CCTGTCATCAGCGCCCGCAGCCCCTCCGTGAGCAGCGAGTACTACATCCGCTTGGAGGAGCACGGCTCCCCTCCTGAGCCCCTCTTCCCC
AACGACTGGGACCCCCTGGACCCAGGAGTGCCCGCCCCTCAGGCCCCCCAGGCCCCCTCCGAGGTCCCCCAGCTGGTGTCCGAGACCTGG
GCCTCCCCCCTCTTCCCTGCGCCCCGGCCCTTCCCAGCCCAGTCCTCAGCGTCAGGCAGCTTCCTGCTGAGCGGCTGGGACCCCGAGGGC
CGGGGCGCCGGGGAGACCCTGGCGGGAGACCCTGCCGAGGTCTTGGGGGAGCGGGGGACCGCCCCGTGGGTGGAAGAAGAAGAGGAGGAG
GAGGAGGGCAGCTCCCCAGGGGAAGACAGCAGCAGCCTTGGAGGTGGCCCAAGCCGCCGGGGTCCCCTACCCTGTCCCCTGTGCAGCCGC
GAGGGGGCCTGCTCCTGCCTGCCACTGGAGCGGGGGGACGCCGTAGCAGGCTGGGGAGGCCACCCTGCTCTTGGCTGCCCCCACCCCCCC
GAGGACGACTCCTCGCTGCGGGCAGAGCGGGGCTCCCTGGCCGACTTGCCCATGGCCCCCCCCGCCTCGGCCCCCCCCGAGTTTCTGGAC
CCCCTCATGGGGGCGGCGGCGCCCCAGTACCCCGGGCGGGGGCCACCTCCCGCTCCCCCCCCCCCGCCGCCACCTCCTCGGGCCCCCGCG
GACCCGGCCGCGTCCCCCGACCCCCCTTCGGCCGTGGCCAGTCCCGGTTCAGGCCTCTCGTCGCCGGGCCCCAAGCCGGGGGACAGCGGC
TACGAGACCGAGACCCCTTTTTCCCCAGAGGGAGCCTTCCCAGGTGGGGGGGCGGCCGAGGAGGAAGGGGTCCCTCGGCCGCGGGCTCCC
CCCGAGCCACCCGACCCAGGAGCGCCCCGGCCACCTCCAGACCCGGGTCCGCTCCCACTCCCGGGGCCCCGGGAGAAGCCGACCTTCGTG
GTTCAAGTGAGCACGGAACAGCTGCTGATGTCCCTGCGGGAGGATGTGACAAGGAACCTCCTGGGGGAGAAGGGGGCGACAGCCCGGGAG
ACAGGACCCAGGAAGGCGGGGAGAGGCCCCGGGAACAGAGAGAAAGTCCCGGGCCTGAACAGGGACCCGACAGTCCTGGGCAACGGGAAA
CAAGCCCCAAGCCTGAGCCTCCCAGTGAACGGGGTGACAGTGCTGGAGAACGGGGACCAGAGAGCCCCAGGCATCGAGGAGAAGGCGGCG
GAGAATGGGGCCCTGGGGTCCCCCGAGAGAGAAGAGAAAGTGCTGGAGAATGGGGAGCTGACACCCCCAAGGAGGGAGGAGAAAGCGCTG
GAGAATGGGGAGCTGAGGTCCCCAGAGGCCGGGGAGAAGGTGCTGGTGAATGGGGGCCTGACACCCCCAAAGAGCGAGGACAAGGTGTCA
GAGAATGGGGGCCTGAGATTCCCCAGGAACACGGAGAGGCCACCAGAGACTGGGCCTTGGAGAGCCCCAGGGCCCTGGGAGAAGACGCCC
GAGAGTTGGGGTCCAGCCCCCACGATCGGGGAGCCAGCCCCAGAGACCTCTCTGGAGAGAGCCCCTGCACCCAGCGCAGTGGTCTCCTCC
CGGAACGGCGGGGAGACAGCCCCTGGCCCCCTTGGCCCAGCCCCCAAGAACGGGACGCTGGAACCCGGGACCGAGAGGAGAGCCCCCGAG
ACTGGGGGGGCGCCGAGAGCCCCAGGGGCTGGGAGGCTGGACCTCGGGAGTGGGGGCCGAGCCCCAGTGGGCACGGGGACGGCCCCCGGC
GGCGGCCCCGGAAGCGGCGTGGACGCAAAGGCCGGATGGGTAGACAACACGAGGCCGCAGCCACCGCCGCCACCGCTGCCACCGCCACCG
GAGGCACAGCCGAGGAGGCTGGAGCCAGCGCCCCCGAGAGCCAGGCCGGAGGTGGCCCCCGAGGGAGAGCCCGGGGCCCCAGACAGCAGG
GCCGGCGGAGACACGGCACTCAGCGGAGACGGGGACCCCCCCAAGCCCGAGAGGAAGGGCCCCGAGATGCCACGACTATTCTTGGACTTG
GGACCCCCTCAGGGGAACAGCGAGCAGATCAAAGCCAGGCTCTCCCGGCTCTCGCTGGCGCTGCCGCCGCTCACGCTCACGCCATTCCCG
GGGCCGGGCCCGCGGCGGCCCCCGTGGGAGGGCGCGGACGCCGGGGCGGCTGGCGGGGAGGCCGGCGGGGCGGGAGCGCCGGGGCCGGCG
GAGGAGGACGGGGAGGACGAGGACGAGGACGAGGAGGAGGACGAGGAGGCGGCGGCGCCGGGCGCGGCGGCGGGGCCGCGGGGCCCCGGG
AGGGCGCGAGCAGCCCCGGTGCCCGTCGTGGTGAGCAGCGCCGACGCGGACGCGGCCCGCCCGCTGCGGGGGCTGCTCAAGTCTCCGCGC
GGGGCCGACGAGCCAGAGGACAGCGAGCTGGAGAGGAAGCGCAAGATGGTCTCCTTCCACGGGGACGTGACCGTCTACCTCTTCGACCAG
GAGACGCCAACCAACGAGCTGAGCGTCCAGGCCCCCCCCGAGGGGGACACGGACCCGTCAACGCCTCCAGCGCCCCCGACACCTCCCCAC
CCCGCCACCCCCGGAGATGGGTTTCCCAGCAACGACAGCGGCTTTGGAGGCAGTTTCGAGTGGGCGGAGGATTTCCCCCTCCTCCCCCCT
CCAGGCCCCCCGCTGTGCTTCTCCCGCTTCTCCGTCTCGCCTGCGCTGGAGACCCCGGGGCCACCCGCCCGGGCCCCCGACGCCCGGCCC
GCAGGATGAGAAATACTGGAGCCGGCGGTACAAGAACAACGAGGCAGCCAAGCGGTCCCGTGACGCCCGGCGGCTCAAGGAGAACCAGAT
ATCGGTGCGGGCGGCCTTCCTGGAGAAGGAGAACGCCCTGCTGCGGCAGGAAGTTGTGGCCGTGCGCCAGGAGCTGTCCCACTACCGCGC
CGTGCTGTCCCGATACCAGGCCCAGCACGGGGCCCTGTGAGGCTGCCCCACATCCCCACCTGGCGGAGCTCTCCTCCGCCTTGCTGAGAC
TTACGCCCTGTTCCCTTCCTGCCCTGTGGCCCACGGGCCGGCCAGCTGGGTGCCCCAGGGACGTGATAATGCAGATAAATACATTTATAT
TTTTAAGAAAAAGCGAGCCTCCCCCCTCCCTTGCGGGGGCGGGGAGGGTTCTCTGTGTGTGTCCCCGGCACGTCAGGGACCCTATCCTCC
CACCGCCTCCGTTAACACGATCCTGAATAAATCTTGAGAACCCCAGAGCCAGCTGTTGTGGAAGAAGAGGGCAGCTCCCTGGCATACTGG
CTGCAGCCCGTGGGCAGCTCCGGGCTGTCGTCCATAGAGGGCAGGCGCTGCTGGAAGTGCTGGAGTCTGAGTCCTCCCGCGGGCTGTCGG
ATGGAGGAAGGGCAGAAGGTCTGAGAGGAATGAAGCGACTGCCTTTATTGCATAGACCTTTTCAATTGCTTTTTAGATTGGGGACGGAGG
ACGCGCATGAGACGAACAGGGGATATGAATTTCCCCGCCCCCACCCGCGGGGAGAGGAACATTAGTGCAAATCCTAGCGCCGGCCCCGGG
GAACCTGCCCCTCCTGGGCTGATTGGCCAGCTAAATGGAGGCACCGGAGTGGATGGGGCGAGGCTGCGGGCCCTGACCGGCCGACTCACT
GAGGCCTACCCCAGCCAGTACATTCCAGGTCCTGTCATTGGGCGACGCGTAAAATAGACTCCGCCCTCAGCCATCCTGGCCGGGTAGGAG

>45852_45852_3_LMTK3-DBP_LMTK3_chr19_48994365_ENST00000600059_DBP_chr19_49134309_ENST00000222122_length(amino acids)=1531AA_BP=4
MSASPSLHPSVPSKRGRGVPEPASSPSLPLSCVSCPSPGPGGGQGRAGPHGWGLRARPPLLPSRHHLHLPAILDKMPAPGALILLAAVSA
SGCLASPAHPDGFALGRAPLAPPYAVVLISCSGLLAFIFLLLTCLCCKRGDVGFKEFENPEGEDCSGEYTPPAEETSSSQSLPDVYILPL
AEVSLPMPAPQPSHSDMTTPLGLSRQHLSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQ
CLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDY
GLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPR
LKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDV
LTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPN
DWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEE
EGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDP
LMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPP
EPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQ
APSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSE
NGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPET
GGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRA
GGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAE
EDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQE
TPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETPGPPARAPDARPA

--------------------------------------------------------------
>45852_45852_4_LMTK3-DBP_LMTK3_chr19_48994365_ENST00000600059_DBP_chr19_49134309_ENST00000599385_length(transcript)=4962nt_BP=4594nt
CCTCTGTCCGCCTCTCCATCCCTTCATCCGTCTGTCCCTTCAAAGAGGGGGAGGGGGGTACCTGAGCCAGCAAGCAGCCCCTCCCTCCCC
CTGTCCTGCGTCTCCTGCCCCTCTCCTGGGCCGGGAGGAGGCCAGGGTCGCGCGGGTCCCCATGGCTGGGGGCTGAGGGCCCGCCCCCCC
CTCCTCCCCAGCCGCCACCACCTCCACCTCCCTGCCATCCTCGACAAGATGCCTGCCCCCGGCGCCCTCATCCTCCTTGCGGCCGTCTCC
GCCTCCGGCTGCCTGGCGTCCCCGGCCCACCCCGATGGATTCGCCCTGGGCCGGGCTCCTCTGGCTCCTCCCTACGCTGTGGTCCTCATT
TCCTGCTCCGGCCTGCTGGCCTTCATCTTCCTCCTCCTCACCTGTCTGTGCTGCAAACGGGGCGATGTCGGCTTCAAGGAATTTGAGAAC
CCTGAAGGGGAGGACTGCTCCGGGGAGTACACTCCCCCTGCGGAGGAGACCTCCTCCTCACAGTCGCTGCCTGATGTCTACATTCTCCCG
CTGGCTGAGGTCTCCCTGCCAATGCCTGCCCCGCAGCCTTCACACTCAGACATGACCACCCCCCTGGGCCTTAGCCGGCAGCACCTGAGC
TACCTGCAGGAGATTGGGAGTGGCTGGTTTGGGAAGGTGATCCTGGGAGAGATTTTCTCCGACTACACCCCCGCCCAGGTGGTGGTGAAG
GAGCTCCGAGCCAGCGCGGGGCCCCTGGAGCAACGCAAGTTCATCTCGGAAGCACAGCCGTACAGGAGCCTGCAGCACCCCAATGTCCTC
CAGTGCCTGGGTCTGTGCGTGGAGACGCTGCCGTTTCTGCTGATTATGGAGTTCTGTCAACTGGGGGACCTGAAGCGTTACCTCCGAGCC
CAGCGGCCCCCCGAGGGCCTGTCCCCTGAGCTACCCCCTCGAGACCTGCGGACGCTGCAGAGGATGGGCCTGGAGATCGCCCGCGGGCTG
GCGCACCTGCATTCCCACAACTACGTGCACAGCGACCTGGCCCTGCGCAACTGCCTGCTGACCTCTGACCTGACCGTGCGCATCGGAGAC
TACGGGCTGGCCCACAGCAACTACAAGGAGGACTACTACCTGACCCCAGAGCGCCTGTGGATCCCACTGCGCTGGGCGGCGCCCGAGCTC
CTCGGGGAGCTCCACGGGACCTTCATGGTGGTGGACCAGAGCCGCGAGAGCAACATCTGGTCCCTGGGGGTGACCCTGTGGGAGCTGTTT
GAGTTTGGGGCCCAGCCCTACCGCCACCTGTCAGACGAGGAGGTCCTCGCCTTCGTGGTCCGCCAGCAGCATGTGAAGCTGGCCCGGCCG
AGGCTCAAGCTGCCTTACGCGGACTACTGGTATGACATTCTTCAGTCCTGCTGGCGGCCACCTGCCCAGCGCCCTTCAGCCTCTGATCTC
CAATTGCAGCTCACCTACTTGCTCTCCGAGCGGCCTCCCCGGCCCCCACCGCCGCCACCCCCACCCCGAGACGGTCCCTTCCCCTGGCCC
TGGCCCCCTGCACACAGTGCGCCCCGCCCGGGGACCCTCTCCTCACCGTTCCCCCTACTGGATGGCTTCCCTGGAGCCGACCCCGACGAT
GTGCTCACGGTCACCGAGAGTAGCCGCGGCCTCAACCTCGAGTGCCTGTGGGAGAAGGCCCGGCGTGGGGCCGGCCGGGGTGGGGGGGCA
CCTGCCTGGCAGCCGGCGTCGGCCCCCCCGGCCCCCCACGCCAACCCCTCCAACCCTTTCTACGAGGCGCTGTCCACGCCCAGCGTGCTG
CCTGTCATCAGCGCCCGCAGCCCCTCCGTGAGCAGCGAGTACTACATCCGCTTGGAGGAGCACGGCTCCCCTCCTGAGCCCCTCTTCCCC
AACGACTGGGACCCCCTGGACCCAGGAGTGCCCGCCCCTCAGGCCCCCCAGGCCCCCTCCGAGGTCCCCCAGCTGGTGTCCGAGACCTGG
GCCTCCCCCCTCTTCCCTGCGCCCCGGCCCTTCCCAGCCCAGTCCTCAGCGTCAGGCAGCTTCCTGCTGAGCGGCTGGGACCCCGAGGGC
CGGGGCGCCGGGGAGACCCTGGCGGGAGACCCTGCCGAGGTCTTGGGGGAGCGGGGGACCGCCCCGTGGGTGGAAGAAGAAGAGGAGGAG
GAGGAGGGCAGCTCCCCAGGGGAAGACAGCAGCAGCCTTGGAGGTGGCCCAAGCCGCCGGGGTCCCCTACCCTGTCCCCTGTGCAGCCGC
GAGGGGGCCTGCTCCTGCCTGCCACTGGAGCGGGGGGACGCCGTAGCAGGCTGGGGAGGCCACCCTGCTCTTGGCTGCCCCCACCCCCCC
GAGGACGACTCCTCGCTGCGGGCAGAGCGGGGCTCCCTGGCCGACTTGCCCATGGCCCCCCCCGCCTCGGCCCCCCCCGAGTTTCTGGAC
CCCCTCATGGGGGCGGCGGCGCCCCAGTACCCCGGGCGGGGGCCACCTCCCGCTCCCCCCCCCCCGCCGCCACCTCCTCGGGCCCCCGCG
GACCCGGCCGCGTCCCCCGACCCCCCTTCGGCCGTGGCCAGTCCCGGTTCAGGCCTCTCGTCGCCGGGCCCCAAGCCGGGGGACAGCGGC
TACGAGACCGAGACCCCTTTTTCCCCAGAGGGAGCCTTCCCAGGTGGGGGGGCGGCCGAGGAGGAAGGGGTCCCTCGGCCGCGGGCTCCC
CCCGAGCCACCCGACCCAGGAGCGCCCCGGCCACCTCCAGACCCGGGTCCGCTCCCACTCCCGGGGCCCCGGGAGAAGCCGACCTTCGTG
GTTCAAGTGAGCACGGAACAGCTGCTGATGTCCCTGCGGGAGGATGTGACAAGGAACCTCCTGGGGGAGAAGGGGGCGACAGCCCGGGAG
ACAGGACCCAGGAAGGCGGGGAGAGGCCCCGGGAACAGAGAGAAAGTCCCGGGCCTGAACAGGGACCCGACAGTCCTGGGCAACGGGAAA
CAAGCCCCAAGCCTGAGCCTCCCAGTGAACGGGGTGACAGTGCTGGAGAACGGGGACCAGAGAGCCCCAGGCATCGAGGAGAAGGCGGCG
GAGAATGGGGCCCTGGGGTCCCCCGAGAGAGAAGAGAAAGTGCTGGAGAATGGGGAGCTGACACCCCCAAGGAGGGAGGAGAAAGCGCTG
GAGAATGGGGAGCTGAGGTCCCCAGAGGCCGGGGAGAAGGTGCTGGTGAATGGGGGCCTGACACCCCCAAAGAGCGAGGACAAGGTGTCA
GAGAATGGGGGCCTGAGATTCCCCAGGAACACGGAGAGGCCACCAGAGACTGGGCCTTGGAGAGCCCCAGGGCCCTGGGAGAAGACGCCC
GAGAGTTGGGGTCCAGCCCCCACGATCGGGGAGCCAGCCCCAGAGACCTCTCTGGAGAGAGCCCCTGCACCCAGCGCAGTGGTCTCCTCC
CGGAACGGCGGGGAGACAGCCCCTGGCCCCCTTGGCCCAGCCCCCAAGAACGGGACGCTGGAACCCGGGACCGAGAGGAGAGCCCCCGAG
ACTGGGGGGGCGCCGAGAGCCCCAGGGGCTGGGAGGCTGGACCTCGGGAGTGGGGGCCGAGCCCCAGTGGGCACGGGGACGGCCCCCGGC
GGCGGCCCCGGAAGCGGCGTGGACGCAAAGGCCGGATGGGTAGACAACACGAGGCCGCAGCCACCGCCGCCACCGCTGCCACCGCCACCG
GAGGCACAGCCGAGGAGGCTGGAGCCAGCGCCCCCGAGAGCCAGGCCGGAGGTGGCCCCCGAGGGAGAGCCCGGGGCCCCAGACAGCAGG
GCCGGCGGAGACACGGCACTCAGCGGAGACGGGGACCCCCCCAAGCCCGAGAGGAAGGGCCCCGAGATGCCACGACTATTCTTGGACTTG
GGACCCCCTCAGGGGAACAGCGAGCAGATCAAAGCCAGGCTCTCCCGGCTCTCGCTGGCGCTGCCGCCGCTCACGCTCACGCCATTCCCG
GGGCCGGGCCCGCGGCGGCCCCCGTGGGAGGGCGCGGACGCCGGGGCGGCTGGCGGGGAGGCCGGCGGGGCGGGAGCGCCGGGGCCGGCG
GAGGAGGACGGGGAGGACGAGGACGAGGACGAGGAGGAGGACGAGGAGGCGGCGGCGCCGGGCGCGGCGGCGGGGCCGCGGGGCCCCGGG
AGGGCGCGAGCAGCCCCGGTGCCCGTCGTGGTGAGCAGCGCCGACGCGGACGCGGCCCGCCCGCTGCGGGGGCTGCTCAAGTCTCCGCGC
GGGGCCGACGAGCCAGAGGACAGCGAGCTGGAGAGGAAGCGCAAGATGGTCTCCTTCCACGGGGACGTGACCGTCTACCTCTTCGACCAG
GAGACGCCAACCAACGAGCTGAGCGTCCAGGCCCCCCCCGAGGGGGACACGGACCCGTCAACGCCTCCAGCGCCCCCGACACCTCCCCAC
CCCGCCACCCCCGGAGATGGGTTTCCCAGCAACGACAGCGGCTTTGGAGGCAGTTTCGAGTGGGCGGAGGATTTCCCCCTCCTCCCCCCT
CCAGGCCCCCCGCTGTGCTTCTCCCGCTTCTCCGTCTCGCCTGCGCTGGAGACCCCGGGGCCACCCGCCCGGGCCCCCGACGCCCGGCCC
GCAGGATGAGAAATACTGGAGCCGGCGGTACAAGAACAACGAGGCAGCCAAGCGGTCCCGTGACGCCCGGCGGCTCAAGGAGAACCAGAT
ATCGGTGCGGGCGGCCTTCCTGGAGAAGGAGAACGCCCTGCTGCGGCAGGAAGTTGTGGCCGTGCGCCAGGAGCTGTCCCACTACCGCGC
CGTGCTGTCCCGATACCAGGCCCAGCACGGGGCCCTGTGAGGCTGCCCCACATCCCCACCTGGCGGAGCTCTCCTCCGCCTTGCTGAGAC
TTACGCCCTGTTCCCTTCCTGCCCTGTGGCCCACGGGCCGGCCAGCTGGGTGCCCCAGGGACGTGATAATGCAGATAAATACATTTATAT

>45852_45852_4_LMTK3-DBP_LMTK3_chr19_48994365_ENST00000600059_DBP_chr19_49134309_ENST00000599385_length(amino acids)=1531AA_BP=4
MSASPSLHPSVPSKRGRGVPEPASSPSLPLSCVSCPSPGPGGGQGRAGPHGWGLRARPPLLPSRHHLHLPAILDKMPAPGALILLAAVSA
SGCLASPAHPDGFALGRAPLAPPYAVVLISCSGLLAFIFLLLTCLCCKRGDVGFKEFENPEGEDCSGEYTPPAEETSSSQSLPDVYILPL
AEVSLPMPAPQPSHSDMTTPLGLSRQHLSYLQEIGSGWFGKVILGEIFSDYTPAQVVVKELRASAGPLEQRKFISEAQPYRSLQHPNVLQ
CLGLCVETLPFLLIMEFCQLGDLKRYLRAQRPPEGLSPELPPRDLRTLQRMGLEIARGLAHLHSHNYVHSDLALRNCLLTSDLTVRIGDY
GLAHSNYKEDYYLTPERLWIPLRWAAPELLGELHGTFMVVDQSRESNIWSLGVTLWELFEFGAQPYRHLSDEEVLAFVVRQQHVKLARPR
LKLPYADYWYDILQSCWRPPAQRPSASDLQLQLTYLLSERPPRPPPPPPPPRDGPFPWPWPPAHSAPRPGTLSSPFPLLDGFPGADPDDV
LTVTESSRGLNLECLWEKARRGAGRGGGAPAWQPASAPPAPHANPSNPFYEALSTPSVLPVISARSPSVSSEYYIRLEEHGSPPEPLFPN
DWDPLDPGVPAPQAPQAPSEVPQLVSETWASPLFPAPRPFPAQSSASGSFLLSGWDPEGRGAGETLAGDPAEVLGERGTAPWVEEEEEEE
EGSSPGEDSSSLGGGPSRRGPLPCPLCSREGACSCLPLERGDAVAGWGGHPALGCPHPPEDDSSLRAERGSLADLPMAPPASAPPEFLDP
LMGAAAPQYPGRGPPPAPPPPPPPPRAPADPAASPDPPSAVASPGSGLSSPGPKPGDSGYETETPFSPEGAFPGGGAAEEEGVPRPRAPP
EPPDPGAPRPPPDPGPLPLPGPREKPTFVVQVSTEQLLMSLREDVTRNLLGEKGATARETGPRKAGRGPGNREKVPGLNRDPTVLGNGKQ
APSLSLPVNGVTVLENGDQRAPGIEEKAAENGALGSPEREEKVLENGELTPPRREEKALENGELRSPEAGEKVLVNGGLTPPKSEDKVSE
NGGLRFPRNTERPPETGPWRAPGPWEKTPESWGPAPTIGEPAPETSLERAPAPSAVVSSRNGGETAPGPLGPAPKNGTLEPGTERRAPET
GGAPRAPGAGRLDLGSGGRAPVGTGTAPGGGPGSGVDAKAGWVDNTRPQPPPPPLPPPPEAQPRRLEPAPPRARPEVAPEGEPGAPDSRA
GGDTALSGDGDPPKPERKGPEMPRLFLDLGPPQGNSEQIKARLSRLSLALPPLTLTPFPGPGPRRPPWEGADAGAAGGEAGGAGAPGPAE
EDGEDEDEDEEEDEEAAAPGAAAGPRGPGRARAAPVPVVVSSADADAARPLRGLLKSPRGADEPEDSELERKRKMVSFHGDVTVYLFDQE
TPTNELSVQAPPEGDTDPSTPPAPPTPPHPATPGDGFPSNDSGFGGSFEWAEDFPLLPPPGPPLCFSRFSVSPALETPGPPARAPDARPA

--------------------------------------------------------------

Top

Fusion Gene PPI Analysis for LMTK3-DBP

Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in
ChiPPI page.

Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)

Hgene

Hgene's interactors

Tgene

Tgene's interactors

- Retained PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Still interaction with

- Lost PPIs in in-frame fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

- Retained PPIs, but lost function due to frame-shift fusion.

Partner

Gene

Hbp

Tbp

ENST

Strand

BPexon

TotalExon

Protein feature loci

*BPloci

TotalLen

Interaction lost with

Top

Related Drugs for LMTK3-DBP

Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)

Partner

Gene

UniProtAcc

DrugBank ID

Drug name

Drug activity

Drug type

Drug status

Top

Related Diseases for LMTK3-DBP

Diseases associated with fusion partners.
(DisGeNet 4.0)

Partner

Gene

Disease ID

Disease name

# pubmeds

Source