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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANKS1B-CRY1 (FusionGDB2 ID:4803)

Fusion Gene Summary for ANKS1B-CRY1

check button Fusion gene summary
Fusion gene informationFusion gene name: ANKS1B-CRY1
Fusion gene ID: 4803
HgeneTgene
Gene symbol

ANKS1B

CRY1

Gene ID

56899

1407

Gene nameankyrin repeat and sterile alpha motif domain containing 1Bcryptochrome circadian regulator 1
SynonymsAIDA|AIDA-1|ANKS2|EB-1|EB1|cajalin-2DSPD|PHLL1
Cytomap

12q23.1

12q23.3

Type of geneprotein-codingprotein-coding
Descriptionankyrin repeat and sterile alpha motif domain-containing protein 1BE2a-Pbx1-associated proteinamyloid-beta precursor protein intracellular domain associated protein 1cajalin 2cryptochrome-1cryptochrome 1 (photolyase-like)cryptochrome circadian clock 1
Modification date2020031320200313
UniProtAcc.

Q16526

Ensembl transtripts involved in fusion geneENST00000329257, ENST00000332712, 
ENST00000546568, ENST00000546960, 
ENST00000547010, ENST00000547446, 
ENST00000547776, ENST00000549025, 
ENST00000549493, ENST00000549558, 
ENST00000550693, ENST00000333732, 
ENST00000341752, ENST00000550833, 
ENST00000550633, ENST00000008527, 
Fusion gene scores* DoF score19 X 19 X 6=21663 X 4 X 4=48
# samples 214
** MAII scorelog2(21/2166*10)=-3.3665720099422
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(4/48*10)=-0.263034405833794
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANKS1B [Title/Abstract] AND CRY1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANKS1B(99446934)-CRY1(107399026), # samples:1
Anticipated loss of major functional domain due to fusion event.ANKS1B-CRY1 seems lost the major protein functional domain in Hgene partner, which is a essential gene due to the frame-shifted ORF.
ANKS1B-CRY1 seems lost the major protein functional domain in Tgene partner, which is a IUPHAR drug target due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneCRY1

GO:0000122

negative regulation of transcription by RNA polymerase II

12397359|14672706|15147242

TgeneCRY1

GO:0045892

negative regulation of transcription, DNA-templated

12397359|23133559


check buttonFusion gene breakpoints across ANKS1B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across CRY1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerKB3..ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
ChiTaRS5.0N/AAK131279ANKS1Bchr12

99446934

-CRY1chr12

107399026

-


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Fusion Gene ORF analysis for ANKS1B-CRY1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000329257ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000332712ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000546568ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000546960ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000547010ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000547446ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000547776ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000549025ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000549493ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000549558ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
5CDS-intronENST00000550693ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
Frame-shiftENST00000549025ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000329257ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000332712ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000546568ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000546960ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000547010ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000547446ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000547776ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000549493ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000549558ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
In-frameENST00000550693ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
intron-3CDSENST00000333732ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
intron-3CDSENST00000341752ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
intron-3CDSENST00000550833ENST00000008527ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
intron-intronENST00000329257ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000329257ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000332712ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000332712ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000333732ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000333732ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000333732ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
intron-intronENST00000341752ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000341752ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000341752ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-
intron-intronENST00000546568ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000546568ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000546960ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000546960ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000547010ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000547010ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000547446ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000547446ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000547776ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000547776ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000549025ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000549025ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000549493ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000549493ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000549558ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000549558ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000550693ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000550693ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000550833ENST00000008527ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000550833ENST00000550633ANKS1Bchr12

98072807

-CRY1chr12

105909274

-
intron-intronENST00000550833ENST00000550633ANKS1Bchr12

99446934

-CRY1chr12

107399026

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000547776ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-49102778042711423
ENST00000329257ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-49102778042711423
ENST00000547010ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-3938180618932991036
ENST00000549558ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-28427102182203661
ENST00000550693ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-28427102182203661
ENST00000549493ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-28607282362221661
ENST00000547446ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-2612480871973628
ENST00000546568ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-258845601949649
ENST00000332712ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-258845601949649
ENST00000546960ANKS1Bchr1299446934-ENST00000008527CRY1chr12107399026-258845601949649

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000547776ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0003964210.99960357
ENST00000329257ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0003964210.99960357
ENST00000547010ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0003042880.9996958
ENST00000549558ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0013412130.9986588
ENST00000550693ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0013412130.9986588
ENST00000549493ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0013502030.9986498
ENST00000547446ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0010711760.99892884
ENST00000546568ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0011829680.9988171
ENST00000332712ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0011829680.9988171
ENST00000546960ENST00000008527ANKS1Bchr1299446934-CRY1chr12107399026-0.0011829680.9988171

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Fusion Genomic Features for ANKS1B-CRY1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for ANKS1B-CRY1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:99446934/chr12:107399026)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.CRY1

Q16526

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.FUNCTION: Transcriptional repressor which forms a core component of the circadian clock. The circadian clock, an internal time-keeping system, regulates various physiological processes through the generation of approximately 24 hour circadian rhythms in gene expression, which are translated into rhythms in metabolism and behavior. It is derived from the Latin roots 'circa' (about) and 'diem' (day) and acts as an important regulator of a wide array of physiological functions including metabolism, sleep, body temperature, blood pressure, endocrine, immune, cardiovascular, and renal function. Consists of two major components: the central clock, residing in the suprachiasmatic nucleus (SCN) of the brain, and the peripheral clocks that are present in nearly every tissue and organ system. Both the central and peripheral clocks can be reset by environmental cues, also known as Zeitgebers (German for 'timegivers'). The predominant Zeitgeber for the central clock is light, which is sensed by retina and signals directly to the SCN. The central clock entrains the peripheral clocks through neuronal and hormonal signals, body temperature and feeding-related cues, aligning all clocks with the external light/dark cycle. Circadian rhythms allow an organism to achieve temporal homeostasis with its environment at the molecular level by regulating gene expression to create a peak of protein expression once every 24 hours to control when a particular physiological process is most active with respect to the solar day. Transcription and translation of core clock components (CLOCK, NPAS2, ARNTL/BMAL1, ARNTL2/BMAL2, PER1, PER2, PER3, CRY1 and CRY2) plays a critical role in rhythm generation, whereas delays imposed by post-translational modifications (PTMs) are important for determining the period (tau) of the rhythms (tau refers to the period of a rhythm and is the length, in time, of one complete cycle). A diurnal rhythm is synchronized with the day/night cycle, while the ultradian and infradian rhythms have a period shorter and longer than 24 hours, respectively. Disruptions in the circadian rhythms contribute to the pathology of cardiovascular diseases, cancer, metabolic syndromes and aging. A transcription/translation feedback loop (TTFL) forms the core of the molecular circadian clock mechanism. Transcription factors, CLOCK or NPAS2 and ARNTL/BMAL1 or ARNTL2/BMAL2, form the positive limb of the feedback loop, act in the form of a heterodimer and activate the transcription of core clock genes and clock-controlled genes (involved in key metabolic processes), harboring E-box elements (5'-CACGTG-3') within their promoters. The core clock genes: PER1/2/3 and CRY1/2 which are transcriptional repressors form the negative limb of the feedback loop and interact with the CLOCK|NPAS2-ARNTL/BMAL1|ARNTL2/BMAL2 heterodimer inhibiting its activity and thereby negatively regulating their own expression. This heterodimer also activates nuclear receptors NR1D1/2 and RORA/B/G, which form a second feedback loop and which activate and repress ARNTL/BMAL1 transcription, respectively. CRY1 and CRY2 have redundant functions but also differential and selective contributions at least in defining the pace of the SCN circadian clock and its circadian transcriptional outputs. More potent transcriptional repressor in cerebellum and liver than CRY2, though more effective in lengthening the period of the SCN oscillator. On its side, CRY2 seems to play a critical role in tuning SCN circadian period by opposing the action of CRY1. With CRY2, is dispensable for circadian rhythm generation but necessary for the development of intercellular networks for rhythm synchrony. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. Interacts with CLOCK-ARNTL/BMAL1 independently of PER proteins and is found at CLOCK-ARNTL/BMAL1-bound sites, suggesting that CRY may act as a molecular gatekeeper to maintain CLOCK-ARNTL/BMAL1 in a poised and repressed state until the proper time for transcriptional activation. Represses the CLOCK-ARNTL/BMAL1 induced transcription of BHLHE40/DEC1. Represses the CLOCK-ARNTL/BMAL1 induced transcription of ATF4, MTA1, KLF10 and NAMPT (By similarity). May repress circadian target genes expression in collaboration with HDAC1 and HDAC2 through histone deacetylation. Mediates the clock-control activation of ATR and modulates ATR-mediated DNA damage checkpoint. In liver, mediates circadian regulation of cAMP signaling and gluconeogenesis by binding to membrane-coupled G proteins and blocking glucagon-mediated increases in intracellular cAMP concentrations and CREB1 phosphorylation. Inhibits hepatic gluconeogenesis by decreasing nuclear FOXO1 levels that downregulates gluconeogenic gene expression (By similarity). Besides its role in the maintenance of the circadian clock, is also involved in the regulation of other processes. Represses glucocorticoid receptor NR3C1/GR-induced transcriptional activity by binding to glucocorticoid response elements (GREs). Plays a key role in glucose and lipid metabolism modulation, in part, through the transcriptional regulation of genes involved in these pathways, such as LEP or ACSL4 (By similarity). Represses PPARD and its target genes in the skeletal muscle and limits exercise capacity (By similarity). Plays an essential role in the generation of circadian rhythms in the retina (By similarity). Represses the transcriptional activity of NR1I2 (By similarity). {ECO:0000250|UniProtKB:P97784, ECO:0000269|PubMed:10531061, ECO:0000269|PubMed:14672706, ECO:0000269|PubMed:22170608, ECO:0000269|PubMed:23133559, ECO:0000269|PubMed:28388406}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-1726810_8769261249.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-3112_31152427.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-31158_87152427.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-31191_120152427.0RepeatNote=ANK 3
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-3122_31152461.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-31258_87152461.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-31291_120152461.0RepeatNote=ANK 3
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-1018127_156502765.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-1018160_189502765.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-1018193_222502765.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-1018225_254502765.0RepeatNote=ANK 7
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-10182_31502765.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-101858_87502765.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-101891_120502765.0RepeatNote=ANK 3
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-4122_31121395.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-41258_87121395.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-41291_120121395.0RepeatNote=ANK 3
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-1726127_1569261249.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-1726160_1899261249.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-1726193_2229261249.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-1726225_2549261249.0RepeatNote=ANK 7
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-17262_319261249.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-172658_879261249.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-172691_1209261249.0RepeatNote=ANK 3
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-4122_3195358.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-41258_8795358.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-3132_31152511.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-31358_87152511.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-31391_120152511.0RepeatNote=ANK 3
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-3112_31152415.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-31158_87152415.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-31191_120152415.0RepeatNote=ANK 3
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-3122_31152451.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-31258_87152451.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-31291_120152451.0RepeatNote=ANK 3
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113151_15689456.0MotifLIR 3
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113255_26089456.0MotifLIR 4
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113271_27689456.0MotifLIR 5
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113285_29089456.0MotifLIR 6
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113335_33989456.0MotifLIR 7
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113379_38489456.0MotifLIR 8
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113395_40089456.0MotifLIR 9
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113411_41689456.0MotifLIR 10
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113430_43589456.0MotifLIR 11
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113486_49189456.0MotifLIR 12
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113492_49789456.0MotifLIR 13
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113387_38989456.0Nucleotide bindingFAD
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113371_47089456.0RegionRequired for inhibition of CLOCK-ARNTL/BMAL1-mediated transcription

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-1101056_12130255.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-110810_8760255.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-110884_9490255.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-3111056_1213152427.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-311810_876152427.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-311884_949152427.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-3121056_1213152461.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-312810_876152461.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-312884_949152461.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-10181056_1213502765.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-1018810_876502765.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-1018884_949502765.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-4121056_1213121395.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-412810_876121395.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-412884_949121395.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-17261056_12139261249.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-1726884_9499261249.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-4121056_121395358.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-412810_87695358.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-412884_94995358.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-3131056_1213152511.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-313810_876152511.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-313884_949152511.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-3111056_1213152415.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-311810_876152415.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-311884_949152415.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-3121056_1213152451.0DomainPID
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-312810_876152451.0DomainSAM 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-312884_949152451.0DomainSAM 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-110935_9380255.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-311935_938152427.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-312935_938152461.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547010-1018935_938502765.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-412935_938121395.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547776-1726935_9389261249.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-412935_93895358.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-313935_938152511.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-311935_938152415.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-312935_938152451.0MotifNuclear localization signal
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-110127_1560255.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-110160_1890255.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-110193_2220255.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-110225_2540255.0RepeatNote=ANK 7
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-1102_310255.0RepeatNote=ANK 1
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-11058_870255.0RepeatNote=ANK 2
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000341752-11091_1200255.0RepeatNote=ANK 3
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-311127_156152427.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-311160_189152427.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-311193_222152427.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546568-311225_254152427.0RepeatNote=ANK 7
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-312127_156152461.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-312160_189152461.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-312193_222152461.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000546960-312225_254152461.0RepeatNote=ANK 7
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-412127_156121395.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-412160_189121395.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-412193_222121395.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000547446-412225_254121395.0RepeatNote=ANK 7
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-412127_15695358.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-412160_18995358.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-412193_22295358.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-412225_25495358.0RepeatNote=ANK 7
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549025-41291_12095358.0RepeatNote=ANK 3
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-313127_156152511.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-313160_189152511.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-313193_222152511.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549493-313225_254152511.0RepeatNote=ANK 7
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-311127_156152415.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-311160_189152415.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-311193_222152415.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000549558-311225_254152415.0RepeatNote=ANK 7
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-312127_156152451.0RepeatNote=ANK 4
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-312160_189152451.0RepeatNote=ANK 5
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-312193_222152451.0RepeatNote=ANK 6
HgeneANKS1Bchr12:99446934chr12:107399026ENST00000550693-312225_254152451.0RepeatNote=ANK 7
TgeneCRY1chr12:99446934chr12:107399026ENST000000085271133_13289456.0DomainNote=Photolyase/cryptochrome alpha/beta
TgeneCRY1chr12:99446934chr12:107399026ENST0000000852711350_5489456.0MotifLIR 1
TgeneCRY1chr12:99446934chr12:107399026ENST0000000852711382_8789456.0MotifLIR 2


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Fusion Gene Sequence for ANKS1B-CRY1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4803_4803_1_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000329257_CRY1_chr12_107399026_ENST00000008527_length(transcript)=4910nt_BP=2778nt
ATGGGGAAGGACCAGGAGCTGCTGGAAGCTGCTCGCACTGGAAATGTGGCTCTGGTGGAGAAACTCCTGTCTGGCAGGAAAGGAGGGATC
CTGGGCGGTGGATCCGGACCCCTGCCCCTGTCTAATCTGCTAAGCATCTGGCGAGGCCCCAATGTGAACTGCACAGACAGTTCGGGTTAC
ACTGCTTTACACCACGCAGCCTTAAATGGACATAAGGACATAGTTCTCAAACTACTTCAGTATGAGGCATCAACAAATGTAGCAGACAAC
AAAGGGTATTTTCCTATTCACCTGGCTGCCTGGAAAGGAGATGTGGAAATTGTGAAGATTCTTATTCATCATGGACCATCACATTCCAGG
GTCAATGAACAGAACAATGAAAATGAAACTGCCCTACACTGTGCAGCTCAATATGGACACTCAGAAGTAGTTGCTGTTCTCCTAGAAGAG
CTCACTGACCCGACAATTAGAAATAGCAAGCTGGAAACACCTTTGGACTTGGCGGCACTCTACGGACGGCTTAGAGTGGTAAAAATGATC
ATCAGTGCACATCCTAACTTAATGAGCTGCAACACTCGCAAGCACACGCCACTTCACCTTGCTGCGCGCAATGGCCACAAAGCAGTCGTG
CAGGTGCTGCTGGAGGCAGGAATGGATGTGAGCTGTCAAACAGAAAAGGGGAGTGCACTTCATGAAGCAGCTTTGTTTGGAAAGGTGGAT
GTTGTACGAGTTCTGTTAGAAACAGGAATTGATGCCAACATAAAGGATAGCTTAGGTAGAACTGTCTTGGACATTCTGAAAGAACATCCA
TCTCAGAAATCTCTCCAGATTGCAACACTCTTACAAGAGTATTTAGAAGGCGTGGGAAGATCTACAGTCCTCGAAGAGCCTGTACAGGAA
GATGCAACACAAGAAACACACATTTCATCTCCTGTTGAGTCTCCTTCCCAAAAGACCAAAAGTGAAACCGTCACTGGAGAATTATCAAAA
CTCTTGGATGAAATAAAACTCTGTCAAGAAAAGGATTATTCGTTTGAAGACTTGTGCCACACAATATCAGACCACTACTTAGATAATTTG
AGCAAGATTTCAGAGGAAGAACTTGGGAAAAATGGAAGCCAGAGTGTAAGAACCTCATCTACAATCAATTTGTCACCAGGAGAAGTGGAA
GAAGAGGATGATGATGAAAATACGTGTGGGCCATCAGGACTTTGGGAAGCATTAACTCCGTGTAATGGATGTAGGAACCTTGGCTTCCCC
ATGCTTGCCCAGGAGTCCTATCCAAAGAAGAGAAATTACACTATGGAAATTGTACCATCTGCTTCTCTGGATACATTTCCTTCAGAAAAT
GAGAACTTTCTGTGTGATCTCATGGACACAGCTGTTACAAAGAAACCTTGCTCCTTAGAAATTGCAAGGGCACCTTCCCCAAGAACTGAT
AATGCCTCTGAGGTAGCAGTTACTACTCCAGGAACTAGTAACCATAGAAACAGCTCAACAGGCCCAACACCTGATTGTTCACCTCCATCC
CCTGATACTGCCCTCAAAAATATTGTAAAAGTCATTCGACCCCAGCCTAAACAGCGAACATCCATTGTGTCTTCTCTGGATTTTCACCGA
ATGAATCACAACCAAGAATATTTTGAAATCAACACATCTACAGGGTGCACAAGCTTTACTGCCAGTCCTCCTGCTAGTCCACCCACCTCT
TCTGTGGGAACCACAGAAGTCAAGAATGAGGGAACTAACCATACAGATGACCTCTCCCGACAGGATGACAATGATCCCCCAAAAGAATAT
GATCCTGGGCAATTTGCAGGCCTGCTCCATGGATCCTCTCCAGCCTGTGAGTCCCCTGAAAATCCATTTCATCTCTATGGGAAAAGAGAA
CAATGTGAAAAAGGACAAGATGAAGTCAGTTTGGCAAACAGTCCTTTGCCTTTCAAGCAGTCTCCAATAGAAAATAACTCAGAACCTTTG
GTAAAGAAAATTAAACCCAAAGTGGTCAGTAGAACAATTTTTCACAAAAAAAGCAACCAACTCGAAAACCATACCATTGTTGGCACAAGA
TCAACCAGGAGTGGATCTCGGAATGGGGACCAGTGGGTTATGAACGCAGGGGGATTTGTGGAGAGAGCCTGTACTCTGGGGAGAATAAGG
TCATTGCCTAAAGCCTTGATCGACATGCATTTGTCAAAAAGTGTCTCTAAATCTGATTCTGATCTCATTGCCTATCCTTCCAATGAGAAA
ACATCAAGAGTTAACTGGAGTGAATCTTCCACTGCTGAACACAGTTCTAAAGGGAATTCTGAAAGAACACCATCCTTCACATCGGAATGG
GAAGAAATTGACAAAATAATGAGTTCCATAGATGTTGGAATCAACAACGAACTTAAAGAGATGAATGGTGAGACCACAAGACCCAGATGC
CCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAGTACGAGAACCACCTGATGGCTAATGGATTTGACAATGTGCAG
TTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGAATCCTTAATTCTGGGCACAGACAAAGAATTCTACAGGCAATC
CAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCCACCTCTGTAGCTGAGTGGCTGGATTCCATTGAACTGGGCGAC
TACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTGAAAAAAATCTGGGAGGTTGAACTTATTAATGAATGGAACATT
ACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGAGACGCAGCTATTAAGAAACTGGCAACTGAAGCTGGAGTAGAA
GTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATAGAACTCAATGGTGGACAACCGCCTCTAACTTATAAAAGATTC
CAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACAATTACTTCAGAAGTGATAGAAAAGTGCACAACTCCTCTGTCT
GATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGTTTTGATACAGATGGCTTATCCTCTGCAGTGTGGCCAGGTGGA
GAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCTTGGGTGGCAAATTTTGAAAGACCTCGAATGAATGCGAATTCT
CTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGTTTGTCATGTCGACTGTTTTACTTCAAACTAACAGATCTCTAC
AAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAACTGTTATGGCGTGAATTTTTCTATACAGCAGCAACAAATAAT
CCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCTTGGGATAAAAATCCTGAGGCTTTAGCCAAATGGGCGGAAGGC
CGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAGGAGGGTTGGATTCATCATCTAGCCAGGCATGCAGTTGCTTGC
TTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAGGTATTTGAAGAATTATTGCTTGATGCAGATTGGAGCATAAAT
GCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTTTTTCACTGCTATTGCCCTGTTGGTTTTGGTAGGAGAACAGAT
CCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTCCCTGCAAAATATATCTATGATCCCTGGAATGCACCAGAAGGT
ATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCAATGGTGAACCATGCTGAGGCAAGCCGTTTGAATATCGAAAGG
ATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTTCTGGCATCAGTACCTTCTAATCCTAATGGGAATGGAGGCTTC
ATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGTTGCTCTCAAGGGAGTGGTATTTTACACTATGCTCATGGCGAC
AGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACTGGTCTCAGTGGTGGGAAACGTCCTAGTCAGGAAGAGGACACA
CAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACATTCAGGAGGAATACTGTTGCAGCTGAAATTGGTGGGGAGTTC
AATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAGCAGTTACATATTGAAATATGTTGTTTCTAATGACATTTCTGT
GGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGTATATAAAGAACTTGGCAAGAGAATTTGCTTAATGTAAATATA
AACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTTCATGTATGGTAAAGTTAAAATGACAAATTGATATTCTGATAT
AAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACTTTCTTAAAAGACGTTAAAATTTTAGGACAGAATTTTCTTGAT
GTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAATGTGCGTAATCCAAATTGGTATTGTAGCCTCTGTTAACACAGA
CAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTGTGGAAGTATCATGTGTTAAGTTCTCTGTCTCTGTTTCTTTGT

>4803_4803_1_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000329257_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=1423AA_BP=926
MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADN
KGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
ISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP
SQKSLQIATLLQEYLEGVGRSTVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHTISDHYLDNL
SKISEEELGKNGSQSVRTSSTINLSPGEVEEEDDDENTCGPSGLWEALTPCNGCRNLGFPMLAQESYPKKRNYTMEIVPSASLDTFPSEN
ENFLCDLMDTAVTKKPCSLEIARAPSPRTDNASEVAVTTPGTSNHRNSSTGPTPDCSPPSPDTALKNIVKVIRPQPKQRTSIVSSLDFHR
MNHNQEYFEINTSTGCTSFTASPPASPPTSSVGTTEVKNEGTNHTDDLSRQDDNDPPKEYDPGQFAGLLHGSSPACESPENPFHLYGKRE
QCEKGQDEVSLANSPLPFKQSPIENNSEPLVKKIKPKVVSRTIFHKKSNQLENHTIVGTRSTRSGSRNGDQWVMNAGGFVERACTLGRIR
SLPKALIDMHLSKSVSKSDSDLIAYPSNEKTSRVNWSESSTAEHSSKGNSERTPSFTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRC
PVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGD
YTKAFLINGYTSMDLLKKIWEVELINEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRF
QTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANS
LLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEG
RTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTD
PNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGF

--------------------------------------------------------------
>4803_4803_2_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000332712_CRY1_chr12_107399026_ENST00000008527_length(transcript)=2588nt_BP=456nt
ATGATGTGGCAATGCCACCTCTCAGCCCAGGACTACCGCTATTACCCCGTGGACGGCTACTCCCTGCTTAAACGCTTCCCTCTTCATCCT
CTTACAGGACCCAGATGCCCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAGTACGAGAACCACCTGATGGCTAAT
GGATTTGACAATGTGCAGTTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGAATCCTTAATTCTGGGCACAGACAA
AGAATTCTACAGGCAATCCAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCCACCTCTGTAGCTGAGTGGCTGGAT
TCCATTGAACTGGGCGACTACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTGAAAAAAATCTGGGAGGTTGAACTT
ATTAATGAATGGAACATTACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGAGACGCAGCTATTAAGAAACTGGCA
ACTGAAGCTGGAGTAGAAGTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATAGAACTCAATGGTGGACAACCGCCT
CTAACTTATAAAAGATTCCAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACAATTACTTCAGAAGTGATAGAAAAG
TGCACAACTCCTCTGTCTGATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGTTTTGATACAGATGGCTTATCCTCT
GCAGTGTGGCCAGGTGGAGAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCTTGGGTGGCAAATTTTGAAAGACCT
CGAATGAATGCGAATTCTCTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGTTTGTCATGTCGACTGTTTTACTTC
AAACTAACAGATCTCTACAAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAACTGTTATGGCGTGAATTTTTCTAT
ACAGCAGCAACAAATAATCCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCTTGGGATAAAAATCCTGAGGCTTTA
GCCAAATGGGCGGAAGGCCGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAGGAGGGTTGGATTCATCATCTAGCC
AGGCATGCAGTTGCTTGCTTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAGGTATTTGAAGAATTATTGCTTGAT
GCAGATTGGAGCATAAATGCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTTTTTCACTGCTATTGCCCTGTTGGT
TTTGGTAGGAGAACAGATCCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTCCCTGCAAAATATATCTATGATCCC
TGGAATGCACCAGAAGGTATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCAATGGTGAACCATGCTGAGGCAAGC
CGTTTGAATATCGAAAGGATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTTCTGGCATCAGTACCTTCTAATCCT
AATGGGAATGGAGGCTTCATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGTTGCTCTCAAGGGAGTGGTATTTTA
CACTATGCTCATGGCGACAGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACTGGTCTCAGTGGTGGGAAACGTCCT
AGTCAGGAAGAGGACACACAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACATTCAGGAGGAATACTGTTGCAGCT
GAAATTGGTGGGGAGTTCAATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAGCAGTTACATATTGAAATATGTTGT
TTCTAATGACATTTCTGTGGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGTATATAAAGAACTTGGCAAGAGAAT
TTGCTTAATGTAAATATAAACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTTCATGTATGGTAAAGTTAAAATGAC
AAATTGATATTCTGATATAAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACTTTCTTAAAAGACGTTAAAATTTTA
GGACAGAATTTTCTTGATGTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAATGTGCGTAATCCAAATTGGTATTGT
AGCCTCTGTTAACACAGACAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTGTGGAAGTATCATGTGTTAAGTTCT

>4803_4803_2_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000332712_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=649AA_BP=152
MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQ
RILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINEWNITKLSIEYDSEPFGKERDAAIKKLA
TEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSS
AVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFY
TAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLD
ADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEAS
RLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLLKQGRSSMGTGLSGGKRP

--------------------------------------------------------------
>4803_4803_3_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000546568_CRY1_chr12_107399026_ENST00000008527_length(transcript)=2588nt_BP=456nt
ATGATGTGGCAATGCCACCTCTCAGCCCAGGACTACCGCTATTACCCCGTGGACGGCTACTCCCTGCTTAAACGCTTCCCTCTTCATCCT
CTTACAGGACCCAGATGCCCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAGTACGAGAACCACCTGATGGCTAAT
GGATTTGACAATGTGCAGTTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGAATCCTTAATTCTGGGCACAGACAA
AGAATTCTACAGGCAATCCAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCCACCTCTGTAGCTGAGTGGCTGGAT
TCCATTGAACTGGGCGACTACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTGAAAAAAATCTGGGAGGTTGAACTT
ATTAATGAATGGAACATTACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGAGACGCAGCTATTAAGAAACTGGCA
ACTGAAGCTGGAGTAGAAGTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATAGAACTCAATGGTGGACAACCGCCT
CTAACTTATAAAAGATTCCAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACAATTACTTCAGAAGTGATAGAAAAG
TGCACAACTCCTCTGTCTGATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGTTTTGATACAGATGGCTTATCCTCT
GCAGTGTGGCCAGGTGGAGAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCTTGGGTGGCAAATTTTGAAAGACCT
CGAATGAATGCGAATTCTCTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGTTTGTCATGTCGACTGTTTTACTTC
AAACTAACAGATCTCTACAAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAACTGTTATGGCGTGAATTTTTCTAT
ACAGCAGCAACAAATAATCCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCTTGGGATAAAAATCCTGAGGCTTTA
GCCAAATGGGCGGAAGGCCGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAGGAGGGTTGGATTCATCATCTAGCC
AGGCATGCAGTTGCTTGCTTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAGGTATTTGAAGAATTATTGCTTGAT
GCAGATTGGAGCATAAATGCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTTTTTCACTGCTATTGCCCTGTTGGT
TTTGGTAGGAGAACAGATCCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTCCCTGCAAAATATATCTATGATCCC
TGGAATGCACCAGAAGGTATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCAATGGTGAACCATGCTGAGGCAAGC
CGTTTGAATATCGAAAGGATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTTCTGGCATCAGTACCTTCTAATCCT
AATGGGAATGGAGGCTTCATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGTTGCTCTCAAGGGAGTGGTATTTTA
CACTATGCTCATGGCGACAGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACTGGTCTCAGTGGTGGGAAACGTCCT
AGTCAGGAAGAGGACACACAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACATTCAGGAGGAATACTGTTGCAGCT
GAAATTGGTGGGGAGTTCAATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAGCAGTTACATATTGAAATATGTTGT
TTCTAATGACATTTCTGTGGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGTATATAAAGAACTTGGCAAGAGAAT
TTGCTTAATGTAAATATAAACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTTCATGTATGGTAAAGTTAAAATGAC
AAATTGATATTCTGATATAAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACTTTCTTAAAAGACGTTAAAATTTTA
GGACAGAATTTTCTTGATGTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAATGTGCGTAATCCAAATTGGTATTGT
AGCCTCTGTTAACACAGACAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTGTGGAAGTATCATGTGTTAAGTTCT

>4803_4803_3_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000546568_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=649AA_BP=152
MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQ
RILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINEWNITKLSIEYDSEPFGKERDAAIKKLA
TEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSS
AVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFY
TAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLD
ADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEAS
RLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLLKQGRSSMGTGLSGGKRP

--------------------------------------------------------------
>4803_4803_4_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000546960_CRY1_chr12_107399026_ENST00000008527_length(transcript)=2588nt_BP=456nt
ATGATGTGGCAATGCCACCTCTCAGCCCAGGACTACCGCTATTACCCCGTGGACGGCTACTCCCTGCTTAAACGCTTCCCTCTTCATCCT
CTTACAGGACCCAGATGCCCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAGTACGAGAACCACCTGATGGCTAAT
GGATTTGACAATGTGCAGTTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGAATCCTTAATTCTGGGCACAGACAA
AGAATTCTACAGGCAATCCAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCCACCTCTGTAGCTGAGTGGCTGGAT
TCCATTGAACTGGGCGACTACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTGAAAAAAATCTGGGAGGTTGAACTT
ATTAATGAATGGAACATTACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGAGACGCAGCTATTAAGAAACTGGCA
ACTGAAGCTGGAGTAGAAGTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATAGAACTCAATGGTGGACAACCGCCT
CTAACTTATAAAAGATTCCAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACAATTACTTCAGAAGTGATAGAAAAG
TGCACAACTCCTCTGTCTGATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGTTTTGATACAGATGGCTTATCCTCT
GCAGTGTGGCCAGGTGGAGAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCTTGGGTGGCAAATTTTGAAAGACCT
CGAATGAATGCGAATTCTCTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGTTTGTCATGTCGACTGTTTTACTTC
AAACTAACAGATCTCTACAAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAACTGTTATGGCGTGAATTTTTCTAT
ACAGCAGCAACAAATAATCCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCTTGGGATAAAAATCCTGAGGCTTTA
GCCAAATGGGCGGAAGGCCGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAGGAGGGTTGGATTCATCATCTAGCC
AGGCATGCAGTTGCTTGCTTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAGGTATTTGAAGAATTATTGCTTGAT
GCAGATTGGAGCATAAATGCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTTTTTCACTGCTATTGCCCTGTTGGT
TTTGGTAGGAGAACAGATCCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTCCCTGCAAAATATATCTATGATCCC
TGGAATGCACCAGAAGGTATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCAATGGTGAACCATGCTGAGGCAAGC
CGTTTGAATATCGAAAGGATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTTCTGGCATCAGTACCTTCTAATCCT
AATGGGAATGGAGGCTTCATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGTTGCTCTCAAGGGAGTGGTATTTTA
CACTATGCTCATGGCGACAGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACTGGTCTCAGTGGTGGGAAACGTCCT
AGTCAGGAAGAGGACACACAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACATTCAGGAGGAATACTGTTGCAGCT
GAAATTGGTGGGGAGTTCAATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAGCAGTTACATATTGAAATATGTTGT
TTCTAATGACATTTCTGTGGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGTATATAAAGAACTTGGCAAGAGAAT
TTGCTTAATGTAAATATAAACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTTCATGTATGGTAAAGTTAAAATGAC
AAATTGATATTCTGATATAAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACTTTCTTAAAAGACGTTAAAATTTTA
GGACAGAATTTTCTTGATGTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAATGTGCGTAATCCAAATTGGTATTGT
AGCCTCTGTTAACACAGACAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTGTGGAAGTATCATGTGTTAAGTTCT

>4803_4803_4_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000546960_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=649AA_BP=152
MMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQ
RILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINEWNITKLSIEYDSEPFGKERDAAIKKLA
TEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSS
AVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFY
TAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLD
ADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEAS
RLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLLKQGRSSMGTGLSGGKRP

--------------------------------------------------------------
>4803_4803_5_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000547010_CRY1_chr12_107399026_ENST00000008527_length(transcript)=3938nt_BP=1806nt
GGCAAGGACTCTGTGGGGGAGTCGGTGAGAGACTATGGGGAAGGACCAGGAGCTGCTGGAAGCTGCTCGCACTGGAAATGTGGCTCTGGT
GGAGAAACTCCTGTCTGGCAGGAAAGGAGGGATCCTGGGCGGTGGATCCGGACCCCTGCCCCTGTCTAATCTGCTAAGAGAACCTCATCT
ACAATCAATTTGTCACCAGGAGAAGTGGAAGAAGAGGATGATGATGAAAATACGTGTGGGCCATCAGGACTTTGGGAAGCATTAACTCCG
TGTAATGGATGTAGGAACCTTGGCTTCCCCATGCTTGCCCAGGAGTCCTATCCAAAGAAGAGAAATTACACTATGGAAATTGTACCATCT
GCTTCTCTGGATACATTTCCTTCAGAAAATGAGAACTTTCTGTGTGATCTCATGGACACAGCTGTTACAAAGAAACCTTGCTCCTTAGAA
ATTGCAAGGGCACCTTCCCCAAGAACTGATAATGCCTCTGAGGTAGCAGTTACTACTCCAGGAACTAGTAACCATAGAAACAGCTCAACA
GGCCCAACACCTGATTGTTCACCTCCATCCCCTGATACTGCCCTCAAAAATATTGTAAAAGTCATTCGACCCCAGCCTAAACAGCGAACA
TCCATTGTGTCTTCTCTGGATTTTCACCGAATGAATCACAACCAAGAATATTTTGAAATCAACACATCTACAGGGTGCACAAGCTTTACT
GCCAGTCCTCCTGCTAGTCCACCCACCTCTTCTGTGGGAACCACAGAAGTCAAGAATGAGGGAACTAACCATACAGATGACCTCTCCCGA
CAGGATGACAATGATCCCCCAAAAGAATATGATCCTGGGCAATTTGCAGGCCTGCTCCATGGATCCTCTCCAGCCTGTGAGTCCCCTGAA
AATCCATTTCATCTCTATGGGAAAAGAGAACAATGTGAAAAAGGACAAGATGAAGTCAGTTTGGCAAACAGTCCTTTGCCTTTCAAGCAG
TCTCCAATAGAAAATAACTCAGAACCTTTGGTAAAGAAAATTAAACCCAAAGTGGTCAGTAGAACAATTTTTCACAAAAAAAGCAACCAA
CTCGAAAACCATACCATTGTTGGCACAAGATCAACCAGGAGTGGATCTCGGAATGGGGACCAGTGGGTTATGAACGCAGGGGGATTTGTG
GAGAGAGCCTGTACTCTGGGGAGAATAAGGTCATTGCCTAAAGCCTTGATCGACATGCATTTGTCAAAAAGTGTCTCTAAATCTGATTCT
GATCTCATTGCCTATCCTTCCAATGAGAAAACATCAAGAGTTAACTGGAGTGAATCTTCCACTGCTGAACACAGTTCTAAAGGGAATTCT
GAAAGAACACCATCCTTCACATCGGAATGGGAAGAAATTGACAAAATAATGAGTTCCATAGATGTTGGAATCAACAACGAACTTAAAGAG
ATGAATGGACCCAGATGCCCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAGTACGAGAACCACCTGATGGCTAAT
GGATTTGACAATGTGCAGTTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGAATCCTTAATTCTGGGCACAGACAA
AGAATTCTACAGGCAATCCAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCCACCTCTGTAGCTGAGTGGCTGGAT
TCCATTGAACTGGGCGACTACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTGAAAAAAATCTGGGAGGTTGAACTT
ATTAATGAATGGAACATTACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGAGACGCAGCTATTAAGAAACTGGCA
ACTGAAGCTGGAGTAGAAGTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATAGAACTCAATGGTGGACAACCGCCT
CTAACTTATAAAAGATTCCAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACAATTACTTCAGAAGTGATAGAAAAG
TGCACAACTCCTCTGTCTGATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGTTTTGATACAGATGGCTTATCCTCT
GCAGTGTGGCCAGGTGGAGAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCTTGGGTGGCAAATTTTGAAAGACCT
CGAATGAATGCGAATTCTCTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGTTTGTCATGTCGACTGTTTTACTTC
AAACTAACAGATCTCTACAAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAACTGTTATGGCGTGAATTTTTCTAT
ACAGCAGCAACAAATAATCCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCTTGGGATAAAAATCCTGAGGCTTTA
GCCAAATGGGCGGAAGGCCGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAGGAGGGTTGGATTCATCATCTAGCC
AGGCATGCAGTTGCTTGCTTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAGGTATTTGAAGAATTATTGCTTGAT
GCAGATTGGAGCATAAATGCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTTTTTCACTGCTATTGCCCTGTTGGT
TTTGGTAGGAGAACAGATCCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTCCCTGCAAAATATATCTATGATCCC
TGGAATGCACCAGAAGGTATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCAATGGTGAACCATGCTGAGGCAAGC
CGTTTGAATATCGAAAGGATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTTCTGGCATCAGTACCTTCTAATCCT
AATGGGAATGGAGGCTTCATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGTTGCTCTCAAGGGAGTGGTATTTTA
CACTATGCTCATGGCGACAGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACTGGTCTCAGTGGTGGGAAACGTCCT
AGTCAGGAAGAGGACACACAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACATTCAGGAGGAATACTGTTGCAGCT
GAAATTGGTGGGGAGTTCAATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAGCAGTTACATATTGAAATATGTTGT
TTCTAATGACATTTCTGTGGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGTATATAAAGAACTTGGCAAGAGAAT
TTGCTTAATGTAAATATAAACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTTCATGTATGGTAAAGTTAAAATGAC
AAATTGATATTCTGATATAAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACTTTCTTAAAAGACGTTAAAATTTTA
GGACAGAATTTTCTTGATGTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAATGTGCGTAATCCAAATTGGTATTGT
AGCCTCTGTTAACACAGACAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTGTGGAAGTATCATGTGTTAAGTTCT

>4803_4803_5_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000547010_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=1036AA_BP=539
MSPGEVEEEDDDENTCGPSGLWEALTPCNGCRNLGFPMLAQESYPKKRNYTMEIVPSASLDTFPSENENFLCDLMDTAVTKKPCSLEIAR
APSPRTDNASEVAVTTPGTSNHRNSSTGPTPDCSPPSPDTALKNIVKVIRPQPKQRTSIVSSLDFHRMNHNQEYFEINTSTGCTSFTASP
PASPPTSSVGTTEVKNEGTNHTDDLSRQDDNDPPKEYDPGQFAGLLHGSSPACESPENPFHLYGKREQCEKGQDEVSLANSPLPFKQSPI
ENNSEPLVKKIKPKVVSRTIFHKKSNQLENHTIVGTRSTRSGSRNGDQWVMNAGGFVERACTLGRIRSLPKALIDMHLSKSVSKSDSDLI
AYPSNEKTSRVNWSESSTAEHSSKGNSERTPSFTSEWEEIDKIMSSIDVGINNELKEMNGPRCPVQTVGQWLESIGLPQYENHLMANGFD
NVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINE
WNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTT
PLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLT
DLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHA
VACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNA
PEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYA

--------------------------------------------------------------
>4803_4803_6_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000547446_CRY1_chr12_107399026_ENST00000008527_length(transcript)=2612nt_BP=480nt
GTAACGTATAACCAGTATGAAGATTCAATTCAGATTTAAGCACTTTGGTTTGCTTTTGAATCTTGCTATTTTCTGCATTTGTTTTGACTG
CTCTCATCATTCAAGATTGACGCTTGGATGGGACCCAGATGCCCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAG
TACGAGAACCACCTGATGGCTAATGGATTTGACAATGTGCAGTTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGA
ATCCTTAATTCTGGGCACAGACAAAGAATTCTACAGGCAATCCAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCC
ACCTCTGTAGCTGAGTGGCTGGATTCCATTGAACTGGGCGACTACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTG
AAAAAAATCTGGGAGGTTGAACTTATTAATGAATGGAACATTACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGA
GACGCAGCTATTAAGAAACTGGCAACTGAAGCTGGAGTAGAAGTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATA
GAACTCAATGGTGGACAACCGCCTCTAACTTATAAAAGATTCCAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACA
ATTACTTCAGAAGTGATAGAAAAGTGCACAACTCCTCTGTCTGATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGT
TTTGATACAGATGGCTTATCCTCTGCAGTGTGGCCAGGTGGAGAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCT
TGGGTGGCAAATTTTGAAAGACCTCGAATGAATGCGAATTCTCTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGT
TTGTCATGTCGACTGTTTTACTTCAAACTAACAGATCTCTACAAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAA
CTGTTATGGCGTGAATTTTTCTATACAGCAGCAACAAATAATCCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCT
TGGGATAAAAATCCTGAGGCTTTAGCCAAATGGGCGGAAGGCCGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAG
GAGGGTTGGATTCATCATCTAGCCAGGCATGCAGTTGCTTGCTTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAG
GTATTTGAAGAATTATTGCTTGATGCAGATTGGAGCATAAATGCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTT
TTTCACTGCTATTGCCCTGTTGGTTTTGGTAGGAGAACAGATCCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTC
CCTGCAAAATATATCTATGATCCCTGGAATGCACCAGAAGGTATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCA
ATGGTGAACCATGCTGAGGCAAGCCGTTTGAATATCGAAAGGATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTT
CTGGCATCAGTACCTTCTAATCCTAATGGGAATGGAGGCTTCATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGT
TGCTCTCAAGGGAGTGGTATTTTACACTATGCTCATGGCGACAGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACT
GGTCTCAGTGGTGGGAAACGTCCTAGTCAGGAAGAGGACACACAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACA
TTCAGGAGGAATACTGTTGCAGCTGAAATTGGTGGGGAGTTCAATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAG
CAGTTACATATTGAAATATGTTGTTTCTAATGACATTTCTGTGGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGT
ATATAAAGAACTTGGCAAGAGAATTTGCTTAATGTAAATATAAACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTT
CATGTATGGTAAAGTTAAAATGACAAATTGATATTCTGATATAAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACT
TTCTTAAAAGACGTTAAAATTTTAGGACAGAATTTTCTTGATGTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAAT
GTGCGTAATCCAAATTGGTATTGTAGCCTCTGTTAACACAGACAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTG
TGGAAGTATCATGTGTTAAGTTCTCTGTCTCTGTTTCTTTGTTCATTTATTACTAAAATGAACTTGTTATTAAAGTATATGCAAATATGA

>4803_4803_6_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000547446_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=628AA_BP=131
MLSSFKIDAWMGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYH
PTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKI
IELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERK
AWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQI
PWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQ
FFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLG

--------------------------------------------------------------
>4803_4803_7_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000547776_CRY1_chr12_107399026_ENST00000008527_length(transcript)=4910nt_BP=2778nt
ATGGGGAAGGACCAGGAGCTGCTGGAAGCTGCTCGCACTGGAAATGTGGCTCTGGTGGAGAAACTCCTGTCTGGCAGGAAAGGAGGGATC
CTGGGCGGTGGATCCGGACCCCTGCCCCTGTCTAATCTGCTAAGCATCTGGCGAGGCCCCAATGTGAACTGCACAGACAGTTCGGGTTAC
ACTGCTTTACACCACGCAGCCTTAAATGGACATAAGGACATAGTTCTCAAACTACTTCAGTATGAGGCATCAACAAATGTAGCAGACAAC
AAAGGGTATTTTCCTATTCACCTGGCTGCCTGGAAAGGAGATGTGGAAATTGTGAAGATTCTTATTCATCATGGACCATCACATTCCAGG
GTCAATGAACAGAACAATGAAAATGAAACTGCCCTACACTGTGCAGCTCAATATGGACACTCAGAAGTAGTTGCTGTTCTCCTAGAAGAG
CTCACTGACCCGACAATTAGAAATAGCAAGCTGGAAACACCTTTGGACTTGGCGGCACTCTACGGACGGCTTAGAGTGGTAAAAATGATC
ATCAGTGCACATCCTAACTTAATGAGCTGCAACACTCGCAAGCACACGCCACTTCACCTTGCTGCGCGCAATGGCCACAAAGCAGTCGTG
CAGGTGCTGCTGGAGGCAGGAATGGATGTGAGCTGTCAAACAGAAAAGGGGAGTGCACTTCATGAAGCAGCTTTGTTTGGAAAGGTGGAT
GTTGTACGAGTTCTGTTAGAAACAGGAATTGATGCCAACATAAAGGATAGCTTAGGTAGAACTGTCTTGGACATTCTGAAAGAACATCCA
TCTCAGAAATCTCTCCAGATTGCAACACTCTTACAAGAGTATTTAGAAGGCGTGGGAAGATCTACAGTCCTCGAAGAGCCTGTACAGGAA
GATGCAACACAAGAAACACACATTTCATCTCCTGTTGAGTCTCCTTCCCAAAAGACCAAAAGTGAAACCGTCACTGGAGAATTATCAAAA
CTCTTGGATGAAATAAAACTCTGTCAAGAAAAGGATTATTCGTTTGAAGACTTGTGCCACACAATATCAGACCACTACTTAGATAATTTG
AGCAAGATTTCAGAGGAAGAACTTGGGAAAAATGGAAGCCAGAGTGTAAGAACCTCATCTACAATCAATTTGTCACCAGGAGAAGTGGAA
GAAGAGGATGATGATGAAAATACGTGTGGGCCATCAGGACTTTGGGAAGCATTAACTCCGTGTAATGGATGTAGGAACCTTGGCTTCCCC
ATGCTTGCCCAGGAGTCCTATCCAAAGAAGAGAAATTACACTATGGAAATTGTACCATCTGCTTCTCTGGATACATTTCCTTCAGAAAAT
GAGAACTTTCTGTGTGATCTCATGGACACAGCTGTTACAAAGAAACCTTGCTCCTTAGAAATTGCAAGGGCACCTTCCCCAAGAACTGAT
AATGCCTCTGAGGTAGCAGTTACTACTCCAGGAACTAGTAACCATAGAAACAGCTCAACAGGCCCAACACCTGATTGTTCACCTCCATCC
CCTGATACTGCCCTCAAAAATATTGTAAAAGTCATTCGACCCCAGCCTAAACAGCGAACATCCATTGTGTCTTCTCTGGATTTTCACCGA
ATGAATCACAACCAAGAATATTTTGAAATCAACACATCTACAGGGTGCACAAGCTTTACTGCCAGTCCTCCTGCTAGTCCACCCACCTCT
TCTGTGGGAACCACAGAAGTCAAGAATGAGGGAACTAACCATACAGATGACCTCTCCCGACAGGATGACAATGATCCCCCAAAAGAATAT
GATCCTGGGCAATTTGCAGGCCTGCTCCATGGATCCTCTCCAGCCTGTGAGTCCCCTGAAAATCCATTTCATCTCTATGGGAAAAGAGAA
CAATGTGAAAAAGGACAAGATGAAGTCAGTTTGGCAAACAGTCCTTTGCCTTTCAAGCAGTCTCCAATAGAAAATAACTCAGAACCTTTG
GTAAAGAAAATTAAACCCAAAGTGGTCAGTAGAACAATTTTTCACAAAAAAAGCAACCAACTCGAAAACCATACCATTGTTGGCACAAGA
TCAACCAGGAGTGGATCTCGGAATGGGGACCAGTGGGTTATGAACGCAGGGGGATTTGTGGAGAGAGCCTGTACTCTGGGGAGAATAAGG
TCATTGCCTAAAGCCTTGATCGACATGCATTTGTCAAAAAGTGTCTCTAAATCTGATTCTGATCTCATTGCCTATCCTTCCAATGAGAAA
ACATCAAGAGTTAACTGGAGTGAATCTTCCACTGCTGAACACAGTTCTAAAGGGAATTCTGAAAGAACACCATCCTTCACATCGGAATGG
GAAGAAATTGACAAAATAATGAGTTCCATAGATGTTGGAATCAACAACGAACTTAAAGAGATGAATGGTGAGACCACAAGACCCAGATGC
CCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAGTACGAGAACCACCTGATGGCTAATGGATTTGACAATGTGCAG
TTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGAATCCTTAATTCTGGGCACAGACAAAGAATTCTACAGGCAATC
CAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCCACCTCTGTAGCTGAGTGGCTGGATTCCATTGAACTGGGCGAC
TACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTGAAAAAAATCTGGGAGGTTGAACTTATTAATGAATGGAACATT
ACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGAGACGCAGCTATTAAGAAACTGGCAACTGAAGCTGGAGTAGAA
GTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATAGAACTCAATGGTGGACAACCGCCTCTAACTTATAAAAGATTC
CAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACAATTACTTCAGAAGTGATAGAAAAGTGCACAACTCCTCTGTCT
GATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGTTTTGATACAGATGGCTTATCCTCTGCAGTGTGGCCAGGTGGA
GAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCTTGGGTGGCAAATTTTGAAAGACCTCGAATGAATGCGAATTCT
CTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGTTTGTCATGTCGACTGTTTTACTTCAAACTAACAGATCTCTAC
AAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAACTGTTATGGCGTGAATTTTTCTATACAGCAGCAACAAATAAT
CCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCTTGGGATAAAAATCCTGAGGCTTTAGCCAAATGGGCGGAAGGC
CGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAGGAGGGTTGGATTCATCATCTAGCCAGGCATGCAGTTGCTTGC
TTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAGGTATTTGAAGAATTATTGCTTGATGCAGATTGGAGCATAAAT
GCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTTTTTCACTGCTATTGCCCTGTTGGTTTTGGTAGGAGAACAGAT
CCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTCCCTGCAAAATATATCTATGATCCCTGGAATGCACCAGAAGGT
ATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCAATGGTGAACCATGCTGAGGCAAGCCGTTTGAATATCGAAAGG
ATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTTCTGGCATCAGTACCTTCTAATCCTAATGGGAATGGAGGCTTC
ATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGTTGCTCTCAAGGGAGTGGTATTTTACACTATGCTCATGGCGAC
AGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACTGGTCTCAGTGGTGGGAAACGTCCTAGTCAGGAAGAGGACACA
CAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACATTCAGGAGGAATACTGTTGCAGCTGAAATTGGTGGGGAGTTC
AATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAGCAGTTACATATTGAAATATGTTGTTTCTAATGACATTTCTGT
GGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGTATATAAAGAACTTGGCAAGAGAATTTGCTTAATGTAAATATA
AACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTTCATGTATGGTAAAGTTAAAATGACAAATTGATATTCTGATAT
AAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACTTTCTTAAAAGACGTTAAAATTTTAGGACAGAATTTTCTTGAT
GTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAATGTGCGTAATCCAAATTGGTATTGTAGCCTCTGTTAACACAGA
CAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTGTGGAAGTATCATGTGTTAAGTTCTCTGTCTCTGTTTCTTTGT

>4803_4803_7_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000547776_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=1423AA_BP=926
MGKDQELLEAARTGNVALVEKLLSGRKGGILGGGSGPLPLSNLLSIWRGPNVNCTDSSGYTALHHAALNGHKDIVLKLLQYEASTNVADN
KGYFPIHLAAWKGDVEIVKILIHHGPSHSRVNEQNNENETALHCAAQYGHSEVVAVLLEELTDPTIRNSKLETPLDLAALYGRLRVVKMI
ISAHPNLMSCNTRKHTPLHLAARNGHKAVVQVLLEAGMDVSCQTEKGSALHEAALFGKVDVVRVLLETGIDANIKDSLGRTVLDILKEHP
SQKSLQIATLLQEYLEGVGRSTVLEEPVQEDATQETHISSPVESPSQKTKSETVTGELSKLLDEIKLCQEKDYSFEDLCHTISDHYLDNL
SKISEEELGKNGSQSVRTSSTINLSPGEVEEEDDDENTCGPSGLWEALTPCNGCRNLGFPMLAQESYPKKRNYTMEIVPSASLDTFPSEN
ENFLCDLMDTAVTKKPCSLEIARAPSPRTDNASEVAVTTPGTSNHRNSSTGPTPDCSPPSPDTALKNIVKVIRPQPKQRTSIVSSLDFHR
MNHNQEYFEINTSTGCTSFTASPPASPPTSSVGTTEVKNEGTNHTDDLSRQDDNDPPKEYDPGQFAGLLHGSSPACESPENPFHLYGKRE
QCEKGQDEVSLANSPLPFKQSPIENNSEPLVKKIKPKVVSRTIFHKKSNQLENHTIVGTRSTRSGSRNGDQWVMNAGGFVERACTLGRIR
SLPKALIDMHLSKSVSKSDSDLIAYPSNEKTSRVNWSESSTAEHSSKGNSERTPSFTSEWEEIDKIMSSIDVGINNELKEMNGETTRPRC
PVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDLLEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGD
YTKAFLINGYTSMDLLKKIWEVELINEWNITKLSIEYDSEPFGKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRF
QTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSLEELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANS
LLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLSLYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEG
RTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWEEGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTD
PNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVNYPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGF

--------------------------------------------------------------
>4803_4803_8_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000549493_CRY1_chr12_107399026_ENST00000008527_length(transcript)=2860nt_BP=728nt
ATTGCTCATTGTGGAGTACTCCAACAATCACATAGAACGCAGACCAGCCCAAGCTGACAGCTTGATATGCCTTCTTCTGCTGCCTGGTTT
TGGGGGCTGTATGACGTACTGGTCGGTAGTAAAGATTAATATGTAAGAAATGTGGAGCTAGGATCAAGTCATACTCCACAGCCTGCCTGG
CAAACTATGTTTTACTTCTGACTTTGCTCTCTCGCTGAGAACATTAATCTGTCAAGCTGGCGGGCTCCTTTGATAGCAACTTTCCCAGGG
GCATGATGTGGCAATGCCACCTCTCAGCCCAGGACTACCGCTATTACCCCGTGGACGGCTACTCCCTGCTTAAACGCTTCCCTCTTCATC
CTCTTACAGGACCCAGATGCCCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAGTACGAGAACCACCTGATGGCTA
ATGGATTTGACAATGTGCAGTTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGAATCCTTAATTCTGGGCACAGAC
AAAGAATTCTACAGGCAATCCAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCCACCTCTGTAGCTGAGTGGCTGG
ATTCCATTGAACTGGGCGACTACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTGAAAAAAATCTGGGAGGTTGAAC
TTATTAATGAATGGAACATTACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGAGACGCAGCTATTAAGAAACTGG
CAACTGAAGCTGGAGTAGAAGTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATAGAACTCAATGGTGGACAACCGC
CTCTAACTTATAAAAGATTCCAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACAATTACTTCAGAAGTGATAGAAA
AGTGCACAACTCCTCTGTCTGATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGTTTTGATACAGATGGCTTATCCT
CTGCAGTGTGGCCAGGTGGAGAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCTTGGGTGGCAAATTTTGAAAGAC
CTCGAATGAATGCGAATTCTCTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGTTTGTCATGTCGACTGTTTTACT
TCAAACTAACAGATCTCTACAAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAACTGTTATGGCGTGAATTTTTCT
ATACAGCAGCAACAAATAATCCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCTTGGGATAAAAATCCTGAGGCTT
TAGCCAAATGGGCGGAAGGCCGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAGGAGGGTTGGATTCATCATCTAG
CCAGGCATGCAGTTGCTTGCTTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAGGTATTTGAAGAATTATTGCTTG
ATGCAGATTGGAGCATAAATGCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTTTTTCACTGCTATTGCCCTGTTG
GTTTTGGTAGGAGAACAGATCCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTCCCTGCAAAATATATCTATGATC
CCTGGAATGCACCAGAAGGTATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCAATGGTGAACCATGCTGAGGCAA
GCCGTTTGAATATCGAAAGGATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTTCTGGCATCAGTACCTTCTAATC
CTAATGGGAATGGAGGCTTCATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGTTGCTCTCAAGGGAGTGGTATTT
TACACTATGCTCATGGCGACAGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACTGGTCTCAGTGGTGGGAAACGTC
CTAGTCAGGAAGAGGACACACAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACATTCAGGAGGAATACTGTTGCAG
CTGAAATTGGTGGGGAGTTCAATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAGCAGTTACATATTGAAATATGTT
GTTTCTAATGACATTTCTGTGGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGTATATAAAGAACTTGGCAAGAGA
ATTTGCTTAATGTAAATATAAACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTTCATGTATGGTAAAGTTAAAATG
ACAAATTGATATTCTGATATAAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACTTTCTTAAAAGACGTTAAAATTT
TAGGACAGAATTTTCTTGATGTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAATGTGCGTAATCCAAATTGGTATT
GTAGCCTCTGTTAACACAGACAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTGTGGAAGTATCATGTGTTAAGTT

>4803_4803_8_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000549493_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=661AA_BP=164
MAGSFDSNFPRGMMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDL
LEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINEWNITKLSIEYDSEPF
GKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSL
EELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLS
LYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWE
EGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVN
YPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLLKQGRS

--------------------------------------------------------------
>4803_4803_9_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000549558_CRY1_chr12_107399026_ENST00000008527_length(transcript)=2842nt_BP=710nt
CTCCAACAATCACATAGAACGCAGACCAGCCCAAGCTGACAGCTTGATATGCCTTCTTCTGCTGCCTGGTTTTGGGGGCTGTATGACGTA
CTGGTCGGTAGTAAAGATTAATATGTAAGAAATGTGGAGCTAGGATCAAGTCATACTCCACAGCCTGCCTGGCAAACTATGTTTTACTTC
TGACTTTGCTCTCTCGCTGAGAACATTAATCTGTCAAGCTGGCGGGCTCCTTTGATAGCAACTTTCCCAGGGGCATGATGTGGCAATGCC
ACCTCTCAGCCCAGGACTACCGCTATTACCCCGTGGACGGCTACTCCCTGCTTAAACGCTTCCCTCTTCATCCTCTTACAGGACCCAGAT
GCCCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAGTACGAGAACCACCTGATGGCTAATGGATTTGACAATGTGC
AGTTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGAATCCTTAATTCTGGGCACAGACAAAGAATTCTACAGGCAA
TCCAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCCACCTCTGTAGCTGAGTGGCTGGATTCCATTGAACTGGGCG
ACTACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTGAAAAAAATCTGGGAGGTTGAACTTATTAATGAATGGAACA
TTACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGAGACGCAGCTATTAAGAAACTGGCAACTGAAGCTGGAGTAG
AAGTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATAGAACTCAATGGTGGACAACCGCCTCTAACTTATAAAAGAT
TCCAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACAATTACTTCAGAAGTGATAGAAAAGTGCACAACTCCTCTGT
CTGATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGTTTTGATACAGATGGCTTATCCTCTGCAGTGTGGCCAGGTG
GAGAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCTTGGGTGGCAAATTTTGAAAGACCTCGAATGAATGCGAATT
CTCTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGTTTGTCATGTCGACTGTTTTACTTCAAACTAACAGATCTCT
ACAAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAACTGTTATGGCGTGAATTTTTCTATACAGCAGCAACAAATA
ATCCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCTTGGGATAAAAATCCTGAGGCTTTAGCCAAATGGGCGGAAG
GCCGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAGGAGGGTTGGATTCATCATCTAGCCAGGCATGCAGTTGCTT
GCTTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAGGTATTTGAAGAATTATTGCTTGATGCAGATTGGAGCATAA
ATGCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTTTTTCACTGCTATTGCCCTGTTGGTTTTGGTAGGAGAACAG
ATCCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTCCCTGCAAAATATATCTATGATCCCTGGAATGCACCAGAAG
GTATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCAATGGTGAACCATGCTGAGGCAAGCCGTTTGAATATCGAAA
GGATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTTCTGGCATCAGTACCTTCTAATCCTAATGGGAATGGAGGCT
TCATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGTTGCTCTCAAGGGAGTGGTATTTTACACTATGCTCATGGCG
ACAGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACTGGTCTCAGTGGTGGGAAACGTCCTAGTCAGGAAGAGGACA
CACAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACATTCAGGAGGAATACTGTTGCAGCTGAAATTGGTGGGGAGT
TCAATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAGCAGTTACATATTGAAATATGTTGTTTCTAATGACATTTCT
GTGGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGTATATAAAGAACTTGGCAAGAGAATTTGCTTAATGTAAATA
TAAACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTTCATGTATGGTAAAGTTAAAATGACAAATTGATATTCTGAT
ATAAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACTTTCTTAAAAGACGTTAAAATTTTAGGACAGAATTTTCTTG
ATGTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAATGTGCGTAATCCAAATTGGTATTGTAGCCTCTGTTAACACA
GACAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTGTGGAAGTATCATGTGTTAAGTTCTCTGTCTCTGTTTCTTT

>4803_4803_9_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000549558_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=661AA_BP=164
MAGSFDSNFPRGMMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDL
LEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINEWNITKLSIEYDSEPF
GKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSL
EELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLS
LYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWE
EGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVN
YPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLLKQGRS

--------------------------------------------------------------
>4803_4803_10_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000550693_CRY1_chr12_107399026_ENST00000008527_length(transcript)=2842nt_BP=710nt
CTCCAACAATCACATAGAACGCAGACCAGCCCAAGCTGACAGCTTGATATGCCTTCTTCTGCTGCCTGGTTTTGGGGGCTGTATGACGTA
CTGGTCGGTAGTAAAGATTAATATGTAAGAAATGTGGAGCTAGGATCAAGTCATACTCCACAGCCTGCCTGGCAAACTATGTTTTACTTC
TGACTTTGCTCTCTCGCTGAGAACATTAATCTGTCAAGCTGGCGGGCTCCTTTGATAGCAACTTTCCCAGGGGCATGATGTGGCAATGCC
ACCTCTCAGCCCAGGACTACCGCTATTACCCCGTGGACGGCTACTCCCTGCTTAAACGCTTCCCTCTTCATCCTCTTACAGGACCCAGAT
GCCCTGTCCAAACAGTGGGACAATGGTTGGAAAGCATTGGGCTACCTCAGTACGAGAACCACCTGATGGCTAATGGATTTGACAATGTGC
AGTTTATGGGAAGCAATGTTATGGAAGATCAGGATTTGTTGGAAATTGGAATCCTTAATTCTGGGCACAGACAAAGAATTCTACAGGCAA
TCCAGCTCCTTCCAAAGATGAGACCCATTGGGCATGATGGCTACCATCCCACCTCTGTAGCTGAGTGGCTGGATTCCATTGAACTGGGCG
ACTACACCAAAGCCTTTCTAATTAATGGCTACACTTCGATGGACCTGTTGAAAAAAATCTGGGAGGTTGAACTTATTAATGAATGGAACA
TTACTAAACTTTCAATTGAGTATGATTCTGAGCCCTTTGGAAAGGAACGAGACGCAGCTATTAAGAAACTGGCAACTGAAGCTGGAGTAG
AAGTCATTGTAAGAATTTCACATACATTATATGACCTAGACAAGATCATAGAACTCAATGGTGGACAACCGCCTCTAACTTATAAAAGAT
TCCAGACTCTCATCAGCAAAATGGAACCACTAGAGATACCAGTAGAGACAATTACTTCAGAAGTGATAGAAAAGTGCACAACTCCTCTGT
CTGATGACCATGATGAGAAATATGGAGTCCCTTCACTGGAAGAGCTAGGTTTTGATACAGATGGCTTATCCTCTGCAGTGTGGCCAGGTG
GAGAAACTGAAGCACTTACTCGTTTGGAAAGGCATTTGGAAAGAAAAGCTTGGGTGGCAAATTTTGAAAGACCTCGAATGAATGCGAATT
CTCTGCTTGCAAGCCCTACTGGACTTAGTCCTTATCTCCGATTTGGTTGTTTGTCATGTCGACTGTTTTACTTCAAACTAACAGATCTCT
ACAAAAAGGTAAAGAAGAACAGTTCCCCTCCCCTTTCCCTTTATGGGCAACTGTTATGGCGTGAATTTTTCTATACAGCAGCAACAAATA
ATCCACGCTTTGATAAAATGGAAGGAAACCCTATCTGTGTTCAGATTCCTTGGGATAAAAATCCTGAGGCTTTAGCCAAATGGGCGGAAG
GCCGGACAGGCTTTCCATGGATTGATGCCATCATGACACAGCTTCGTCAGGAGGGTTGGATTCATCATCTAGCCAGGCATGCAGTTGCTT
GCTTCCTGACACGAGGGGACCTGTGGATTAGTTGGGAAGAAGGAATGAAGGTATTTGAAGAATTATTGCTTGATGCAGATTGGAGCATAA
ATGCTGGAAGTTGGATGTGGCTGTCTTGTAGTTCCTTTTTTCAACAGTTTTTTCACTGCTATTGCCCTGTTGGTTTTGGTAGGAGAACAG
ATCCCAATGGAGACTATATCAGGCGTTATTTGCCTGTCCTAAGAGGCTTCCCTGCAAAATATATCTATGATCCCTGGAATGCACCAGAAG
GTATCCAAAAGGTAGCCAAATGTTTGATAGGAGTTAATTATCCTAAACCAATGGTGAACCATGCTGAGGCAAGCCGTTTGAATATCGAAA
GGATGAAACAGATCTATCAGCAGCTTTCACGATATAGAGGACTAGGTCTTCTGGCATCAGTACCTTCTAATCCTAATGGGAATGGAGGCT
TCATGGGATATTCTGCAGAAAATATCCCAGGTTGTAGCAGCAGTGGAAGTTGCTCTCAAGGGAGTGGTATTTTACACTATGCTCATGGCG
ACAGTCAGCAAACTCACCTGTTGAAGCAAGGAAGAAGCTCCATGGGCACTGGTCTCAGTGGTGGGAAACGTCCTAGTCAGGAAGAGGACA
CACAGAGTATTGGTCCTAAAGTCCAGAGACAGAGCACTAATTAGAAAACATTCAGGAGGAATACTGTTGCAGCTGAAATTGGTGGGGAGT
TCAATACTTTTCAATTAAGTTATTTAAAAATATTCTTCATTGATGGAAAGCAGTTACATATTGAAATATGTTGTTTCTAATGACATTTCT
GTGGTTTTTAACTTTTTAATGAATTTCACAGAGGACAATTGGTAATTTGTATATAAAGAACTTGGCAAGAGAATTTGCTTAATGTAAATA
TAAACAGTCACAATTAGTATAGACCCATCGATATATTTTTGATAATTTTTCATGTATGGTAAAGTTAAAATGACAAATTGATATTCTGAT
ATAAAACTCAAAGTTTTGAAGTCAGTGGGAAAAAAGGAGGTTTTTAGACTTTCTTAAAAGACGTTAAAATTTTAGGACAGAATTTTCTTG
ATGTTGTTTGATCTAACTTTGCACTCTTTGATAATAATGTTTTAGATAATGTGCGTAATCCAAATTGGTATTGTAGCCTCTGTTAACACA
GACAGTATATGTTTTAAACTTTGATGTAAACCTTTTTAGACCCAAACTTGTGGAAGTATCATGTGTTAAGTTCTCTGTCTCTGTTTCTTT

>4803_4803_10_ANKS1B-CRY1_ANKS1B_chr12_99446934_ENST00000550693_CRY1_chr12_107399026_ENST00000008527_length(amino acids)=661AA_BP=164
MAGSFDSNFPRGMMWQCHLSAQDYRYYPVDGYSLLKRFPLHPLTGPRCPVQTVGQWLESIGLPQYENHLMANGFDNVQFMGSNVMEDQDL
LEIGILNSGHRQRILQAIQLLPKMRPIGHDGYHPTSVAEWLDSIELGDYTKAFLINGYTSMDLLKKIWEVELINEWNITKLSIEYDSEPF
GKERDAAIKKLATEAGVEVIVRISHTLYDLDKIIELNGGQPPLTYKRFQTLISKMEPLEIPVETITSEVIEKCTTPLSDDHDEKYGVPSL
EELGFDTDGLSSAVWPGGETEALTRLERHLERKAWVANFERPRMNANSLLASPTGLSPYLRFGCLSCRLFYFKLTDLYKKVKKNSSPPLS
LYGQLLWREFFYTAATNNPRFDKMEGNPICVQIPWDKNPEALAKWAEGRTGFPWIDAIMTQLRQEGWIHHLARHAVACFLTRGDLWISWE
EGMKVFEELLLDADWSINAGSWMWLSCSSFFQQFFHCYCPVGFGRRTDPNGDYIRRYLPVLRGFPAKYIYDPWNAPEGIQKVAKCLIGVN
YPKPMVNHAEASRLNIERMKQIYQQLSRYRGLGLLASVPSNPNGNGGFMGYSAENIPGCSSSGSCSQGSGILHYAHGDSQQTHLLKQGRS

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Fusion Gene PPI Analysis for ANKS1B-CRY1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
TgeneCRY1chr12:99446934chr12:107399026ENST00000008527113471_49389.0456.0TIMELESS


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANKS1B-CRY1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANKS1B-CRY1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource