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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANLN-EEPD1 (FusionGDB2 ID:4833)

Fusion Gene Summary for ANLN-EEPD1

check button Fusion gene summary
Fusion gene informationFusion gene name: ANLN-EEPD1
Fusion gene ID: 4833
HgeneTgene
Gene symbol

ANLN

EEPD1

Gene ID

54443

80820

Gene nameanillin actin binding proteinendonuclease/exonuclease/phosphatase family domain containing 1
SynonymsFSGS8|Scraps|scraHSPC107
Cytomap

7p14.2

7p14.2

Type of geneprotein-codingprotein-coding
Descriptionanillinendonuclease/exonuclease/phosphatase family domain-containing protein 1
Modification date2020031320200313
UniProtAcc.

Q7L9B9

Ensembl transtripts involved in fusion geneENST00000265748, ENST00000396068, 
ENST00000495714, 		ENST00000242108, 
ENST00000534978, 
Fusion gene scores* DoF score6 X 8 X 7=3366 X 7 X 5=210
# samples 109
** MAII scorelog2(10/336*10)=-1.74846123300404
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(9/210*10)=-1.22239242133645
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANLN [Title/Abstract] AND EEPD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANLN(36459088)-EEPD1(36320723), # samples:2
ANLN(36436028)-EEPD1(36336602), # samples:2
EEPD1(36327386)-ANLN(36435875), # samples:1
Anticipated loss of major functional domain due to fusion event.EEPD1-ANLN seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANLN

GO:0000281

mitotic cytokinesis

10931866


check buttonFusion gene breakpoints across ANLN (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across EEPD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4LUADTCGA-44-6778-01AANLNchr7

36436028

-EEPD1chr7

36336602

+
ChimerDB4LUADTCGA-44-6778-01AANLNchr7

36436028

+EEPD1chr7

36336602

+
ChimerDB4LUADTCGA-44-6778ANLNchr7

36436028

+EEPD1chr7

36336601

+
ChimerDB4OVTCGA-24-2023-01AANLNchr7

36459088

+EEPD1chr7

36320724

+
ChimerDB4OVTCGA-24-2023ANLNchr7

36459088

+EEPD1chr7

36320723

+
ChimerDB4READTCGA-AG-A036ANLNchr7

36459088

+EEPD1chr7

36320723

+


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Fusion Gene ORF analysis for ANLN-EEPD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
In-frameENST00000265748ENST00000242108ANLNchr7

36436028

+EEPD1chr7

36336602

+
In-frameENST00000265748ENST00000242108ANLNchr7

36436028

+EEPD1chr7

36336601

+
In-frameENST00000265748ENST00000242108ANLNchr7

36459088

+EEPD1chr7

36320724

+
In-frameENST00000265748ENST00000242108ANLNchr7

36459088

+EEPD1chr7

36320723

+
In-frameENST00000265748ENST00000534978ANLNchr7

36436028

+EEPD1chr7

36336602

+
In-frameENST00000265748ENST00000534978ANLNchr7

36436028

+EEPD1chr7

36336601

+
In-frameENST00000265748ENST00000534978ANLNchr7

36459088

+EEPD1chr7

36320724

+
In-frameENST00000265748ENST00000534978ANLNchr7

36459088

+EEPD1chr7

36320723

+
In-frameENST00000396068ENST00000242108ANLNchr7

36436028

+EEPD1chr7

36336602

+
In-frameENST00000396068ENST00000242108ANLNchr7

36436028

+EEPD1chr7

36336601

+
In-frameENST00000396068ENST00000242108ANLNchr7

36459088

+EEPD1chr7

36320724

+
In-frameENST00000396068ENST00000242108ANLNchr7

36459088

+EEPD1chr7

36320723

+
In-frameENST00000396068ENST00000534978ANLNchr7

36436028

+EEPD1chr7

36336602

+
In-frameENST00000396068ENST00000534978ANLNchr7

36436028

+EEPD1chr7

36336601

+
In-frameENST00000396068ENST00000534978ANLNchr7

36459088

+EEPD1chr7

36320724

+
In-frameENST00000396068ENST00000534978ANLNchr7

36459088

+EEPD1chr7

36320723

+
intron-3CDSENST00000495714ENST00000242108ANLNchr7

36436028

+EEPD1chr7

36336602

+
intron-3CDSENST00000495714ENST00000242108ANLNchr7

36436028

+EEPD1chr7

36336601

+
intron-3CDSENST00000495714ENST00000242108ANLNchr7

36459088

+EEPD1chr7

36320724

+
intron-3CDSENST00000495714ENST00000242108ANLNchr7

36459088

+EEPD1chr7

36320723

+
intron-3CDSENST00000495714ENST00000534978ANLNchr7

36436028

+EEPD1chr7

36336602

+
intron-3CDSENST00000495714ENST00000534978ANLNchr7

36436028

+EEPD1chr7

36336601

+
intron-3CDSENST00000495714ENST00000534978ANLNchr7

36459088

+EEPD1chr7

36320724

+
intron-3CDSENST00000495714ENST00000534978ANLNchr7

36459088

+EEPD1chr7

36320723

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000265748ANLNchr736459088+ENST00000242108EEPD1chr736320723+520720902212869882
ENST00000265748ANLNchr736459088+ENST00000534978EEPD1chr736320723+338920902212869882
ENST00000396068ANLNchr736459088+ENST00000242108EEPD1chr736320723+508119642062743845
ENST00000396068ANLNchr736459088+ENST00000534978EEPD1chr736320723+326319642062743845
ENST00000265748ANLNchr736459088+ENST00000242108EEPD1chr736320724+520720902212869882
ENST00000265748ANLNchr736459088+ENST00000534978EEPD1chr736320724+338920902212869882
ENST00000396068ANLNchr736459088+ENST00000242108EEPD1chr736320724+508119642062743845
ENST00000396068ANLNchr736459088+ENST00000534978EEPD1chr736320724+326319642062743845

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000265748ENST00000242108ANLNchr736459088+EEPD1chr736320723+0.0015223560.99847764
ENST00000265748ENST00000534978ANLNchr736459088+EEPD1chr736320723+0.0031162280.9968837
ENST00000396068ENST00000242108ANLNchr736459088+EEPD1chr736320723+0.0020778280.99792224
ENST00000396068ENST00000534978ANLNchr736459088+EEPD1chr736320723+0.0044576260.99554235
ENST00000265748ENST00000242108ANLNchr736459088+EEPD1chr736320724+0.0015223560.99847764
ENST00000265748ENST00000534978ANLNchr736459088+EEPD1chr736320724+0.0031162280.9968837
ENST00000396068ENST00000242108ANLNchr736459088+EEPD1chr736320724+0.0020778280.99792224
ENST00000396068ENST00000534978ANLNchr736459088+EEPD1chr736320724+0.0044576260.99554235

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Fusion Genomic Features for ANLN-EEPD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANLNchr736459088+EEPD1chr736320723+1.13E-070.9999999
ANLNchr736459088+EEPD1chr736320723+1.13E-070.9999999
ANLNchr736436028+EEPD1chr736336601+4.29E-121
ANLNchr736436028+EEPD1chr736336601+4.29E-121
ANLNchr736459088+EEPD1chr736320723+1.13E-070.9999999
ANLNchr736459088+EEPD1chr736320723+1.13E-070.9999999
ANLNchr736436028+EEPD1chr736336601+4.29E-121
ANLNchr736436028+EEPD1chr736336601+4.29E-121

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANLN-EEPD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr7:36459088/chr7:36320723)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
.EEPD1

Q7L9B9

FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANLNchr7:36459088chr7:36320723ENST00000265748+1024569_6046231125.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36459088chr7:36320724ENST00000265748+1024569_6046231125.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36436028chr7:36336601ENST00000265748+2241_45571125.0RegionNote=Required for ubiquitination
HgeneANLNchr7:36436028chr7:36336601ENST00000396068+2231_45571088.0RegionNote=Required for ubiquitination
HgeneANLNchr7:36436028chr7:36336602ENST00000265748+2241_45571125.0RegionNote=Required for ubiquitination
HgeneANLNchr7:36436028chr7:36336602ENST00000396068+2231_45571088.0RegionNote=Required for ubiquitination
HgeneANLNchr7:36459088chr7:36320723ENST00000265748+10241_2306231125.0RegionNote=Nuclear localization
HgeneANLNchr7:36459088chr7:36320723ENST00000265748+10241_456231125.0RegionNote=Required for ubiquitination
HgeneANLNchr7:36459088chr7:36320723ENST00000396068+9231_2305861088.0RegionNote=Nuclear localization
HgeneANLNchr7:36459088chr7:36320723ENST00000396068+9231_455861088.0RegionNote=Required for ubiquitination
HgeneANLNchr7:36459088chr7:36320724ENST00000265748+10241_2306231125.0RegionNote=Nuclear localization
HgeneANLNchr7:36459088chr7:36320724ENST00000265748+10241_456231125.0RegionNote=Required for ubiquitination
HgeneANLNchr7:36459088chr7:36320724ENST00000396068+9231_2305861088.0RegionNote=Nuclear localization
HgeneANLNchr7:36459088chr7:36320724ENST00000396068+9231_455861088.0RegionNote=Required for ubiquitination

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANLNchr7:36436028chr7:36336601ENST00000265748+224569_604571125.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36436028chr7:36336601ENST00000396068+223569_604571088.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36436028chr7:36336602ENST00000265748+224569_604571125.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36436028chr7:36336602ENST00000396068+223569_604571088.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36459088chr7:36320723ENST00000396068+923569_6045861088.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36459088chr7:36320724ENST00000396068+923569_6045861088.0Coiled coilOntology_term=ECO:0000255
HgeneANLNchr7:36436028chr7:36336601ENST00000265748+224983_1107571125.0DomainPH
HgeneANLNchr7:36436028chr7:36336601ENST00000396068+223983_1107571088.0DomainPH
HgeneANLNchr7:36436028chr7:36336602ENST00000265748+224983_1107571125.0DomainPH
HgeneANLNchr7:36436028chr7:36336602ENST00000396068+223983_1107571088.0DomainPH
HgeneANLNchr7:36459088chr7:36320723ENST00000265748+1024983_11076231125.0DomainPH
HgeneANLNchr7:36459088chr7:36320723ENST00000396068+923983_11075861088.0DomainPH
HgeneANLNchr7:36459088chr7:36320724ENST00000265748+1024983_11076231125.0DomainPH
HgeneANLNchr7:36459088chr7:36320724ENST00000396068+923983_11075861088.0DomainPH
HgeneANLNchr7:36436028chr7:36336601ENST00000265748+2241_230571125.0RegionNote=Nuclear localization
HgeneANLNchr7:36436028chr7:36336601ENST00000265748+224730_1124571125.0RegionNote=Localization to the cleavage furrow
HgeneANLNchr7:36436028chr7:36336601ENST00000396068+2231_230571088.0RegionNote=Nuclear localization
HgeneANLNchr7:36436028chr7:36336601ENST00000396068+223730_1124571088.0RegionNote=Localization to the cleavage furrow
HgeneANLNchr7:36436028chr7:36336602ENST00000265748+2241_230571125.0RegionNote=Nuclear localization
HgeneANLNchr7:36436028chr7:36336602ENST00000265748+224730_1124571125.0RegionNote=Localization to the cleavage furrow
HgeneANLNchr7:36436028chr7:36336602ENST00000396068+2231_230571088.0RegionNote=Nuclear localization
HgeneANLNchr7:36436028chr7:36336602ENST00000396068+223730_1124571088.0RegionNote=Localization to the cleavage furrow
HgeneANLNchr7:36459088chr7:36320723ENST00000265748+1024730_11246231125.0RegionNote=Localization to the cleavage furrow
HgeneANLNchr7:36459088chr7:36320723ENST00000396068+923730_11245861088.0RegionNote=Localization to the cleavage furrow
HgeneANLNchr7:36459088chr7:36320724ENST00000265748+1024730_11246231125.0RegionNote=Localization to the cleavage furrow
HgeneANLNchr7:36459088chr7:36320724ENST00000396068+923730_11245861088.0RegionNote=Localization to the cleavage furrow
TgeneEEPD1chr7:36436028chr7:36336601ENST000002421085838_67438570.0DomainNote=HhH
TgeneEEPD1chr7:36436028chr7:36336601ENST000005349786938_67438570.0DomainNote=HhH
TgeneEEPD1chr7:36436028chr7:36336602ENST000002421085838_67438570.0DomainNote=HhH
TgeneEEPD1chr7:36436028chr7:36336602ENST000005349786938_67438570.0DomainNote=HhH
TgeneEEPD1chr7:36459088chr7:36320723ENST000002421082838_67310570.0DomainNote=HhH
TgeneEEPD1chr7:36459088chr7:36320723ENST000005349783938_67310570.0DomainNote=HhH
TgeneEEPD1chr7:36459088chr7:36320724ENST000002421082838_67310570.0DomainNote=HhH
TgeneEEPD1chr7:36459088chr7:36320724ENST000005349783938_67310570.0DomainNote=HhH


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Fusion Gene Sequence for ANLN-EEPD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4833_4833_1_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000265748_EEPD1_chr7_36320723_ENST00000242108_length(transcript)=5207nt_BP=2090nt
AGCGCGCATGCTCGCGGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAG
CTGGTTGTGGGAGAGTTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTG
AACCACCGTTTCCATCGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAG
AGAATCTTCAGAGAAAAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAG
CAAGTAACCAGCAGCCCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAG
TAGAAGTTTCTAACTTGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGC
CACAAGCAGCAGATACCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAA
CTGCAGCCTCCTCAGTTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGATGACATTCCTG
AAAGCTCACTCTTCTCACCAATGCCATCAGAGGAAAAGGCTGCTTCCCCTCCCAGACCTCTGCTTTCAAATGCCTCGGCAACTCCAGTTG
GCAGAAGGGGCCGTCTGGCCAATCTTGCTGCAACTATTTGCTCCTGGGAAGATGATGTAAATCACTCATTTGCAAAACAAAACAGTGTAC
AAGAACAGCCTGGTACCGCTTGTTTATCCAAATTTTCCTCTGCAAGTGGAGCATCTGCTAGGATCAATAGCAGCAGTGTTAAGCAGGAAG
CTACATTCTGTTCCCAAAGGGATGGCGATGCCTCTTTGAATAAAGCCCTATCCTCAAGTGCTGATGATGCGTCTTTGGTTAATGCCTCAA
TTTCCAGCTCTGTGAAAGCTACTTCTCCAGTGAAATCTACTACATCTATCACTGATGCTAAAAGTTGTGAGGGACAAAATCCTGAGCTAC
TTCCAAAAACTCCTATTAGTCCTCTGAAAACGGGGGTATCGAAACCAATTGTGAAGTCAACTTTATCCCAGACAGTTCCATCCAAGGGAG
AATTAAGTAGAGAAATTTGTCTGCAATCTCAATCTAAAGACAAATCTACGACACCAGGAGGAACAGGAATTAAGCCTTTCCTGGAACGCT
TTGGAGAGCGTTGTCAAGAACATAGCAAAGAAAGTCCAGCTCGTAGCACACCCCACAGAACCCCCATTATTACTCCAAATACAAAGGCCA
TCCAAGAAAGATTATTCAAGCAAGACACATCTTCATCTACTACCCATTTAGCACAACAGCTCAAGCAGGAACGTCAAAAAGAACTAGCAT
GTCTTCGTGGCCGATTTGACAAGGGCAATATATGGAGTGCAGAAAAAGGCGGAAACTCAAAAAGCAAACAACTAGAAACCAAACAGGAAA
CTCACTGTCAGAGCACTCCCCTCAAAAAACACCAAGGTGTTTCAAAAACTCAGTCACTTCCAGTAACAGAAAAGGTGACCGAAAACCAGA
TACCAGCCAAAAATTCTAGTACAGAACCTAAAGGTTTCACTGAATGCGAAATGACGAAATCTAGCCCTTTGAAAATAACATTGTTTTTAG
AAGAGGACAAATCCTTAAAAGTAACATCAGACCCAAAGGTTGAGCAGAAAATTGAAGTGATACGTGAAATTGAGATGAGTGTGGATGATG
ATGATATCAATAGTTCGAAAGTAATTAATGACCTCTTCAGTGATGTCCTAGAGGAAGGTGAACTAGATATGGAGAAGAGCCAAGAGGAGA
TGGATCAAGCATTAGCAGAAAGCAGCGAAGAACAGGAAGATGCACTGAATATCTCCTCAATGTCTTTACTTGCACCATTGGCACAAACAG
TTGGTGTGGTAAGTCCAGAGTTCTGCACGGAGCTAAACCAGCCGACCCTGCCCAACATCCGCAAGTGGAAGGGGCCCCGGGGATGCTGGA
AGGCTGTTGTTGCTGAGAAGCCCTCGAGTCAGCTCCAGAAGGGAGCTGGGTATGCAGGATTCCTATGGGACGCGGCTGCCGGCATGGAGC
TGAGAGACGCGGGTTCACAGGAGAGCTCGCCAAGCAACGGGCACGGGAAGCTGGCGGGCCCCAGCCCATACCTCGGGAGGTTCAAGGTGG
GAAGTCACGACCTGACCCTTGTTAACCTTCACCTGGCAGCCCTGACCCTCCTGGGGAGCGAGAATCCCAGCAAGAATCACAGTGATGGCC
ACCGGTTGGCGAGCTTTGCACAGACCCTACAGGAAACCCTGAAAGGAGAAAAGGATGTCATTATCTTAGGGGATTTTGGCCAAGGGCCAG
ACAGCAATGACTATGATATCCTGAGGAAAGAAAAGTTCCACCACCTGATCCCCGCGCACACCTTCACCAACATCAGCACCAAGAACCCTC
AAGGCTCGAAGTCTCTGGACAACATCTGGATCAGTAAAAGCTTAAAGAAGGTTTTCACAGGTCACTGGGCTGTGGTGAGAGAAGGCCTCA
CGAACCCTTGGATTCCGGATAACTGGTCTTGGGGCGGGGTGGCTTCTGAACACTGCCCAGTGCTAGCCGAGTTCTACACTGAAAAGGACT
GGAGCAAGAAGGATGCCCCTCGGAACGGCAGCGGGGTGGCCTTGGAGCGAAGTGAAGCCAACATCAAGCACGAGCGATGATGACACCAAA
TCCATGTGTCCACCCTGGGACCCAGGAGGGCACAGCCAAGGAATGAGCCCTGTGGGGTGACGCTTCAGGGCAGAGCTGCCTTTTAATTTT
TATTCTCAGAGCATCAGCACTTGAGGCCTTGCCCCACGCCTTCTCTGTGGACCATTCAGGACCTCCAGTGGGGGTGGCGTGCCAGGCGCG
TACCCCACCAGGTGGGCAAAGCAGAAACCTGCGGGGAGCGGAGACGCCTTTTATCTCTGGATGCCACAGACCTGAGCAGCATTGGGCTGG
CTGTCCGCTGCTGACTGGATGGCAGCACAAAGACAATATGAGCAGAGGGAGGAGAAGAAGGGGTGCTCAGGCTGCGGGCCACAGTCCAGC
AGCGCCAGAAGCACTCATTTCTGACCACCAGGCTATGACGTTCCTGCTGCGCATTACAGAAAGCTTTTAACTGTGATCAGGCACTCTGCT
CAGATACATTGAGTGGCGATTTTTAGTTTTGTTTTGAAAAAATAAACAGATTAACCTGCCTCGCTGCAGTGAGAGCATGGGACAAGTCCG
CCACAGCCCTCCCCCGCCCCCTTCCCCCGCCCCCCAACGCGCAGTGTGTATTTGCACCACGGCAGGTGCCTCTGTGTGGAGCTAGGGTCA
AGCCCTGAGCAGCTTCACTTCCCCTGCGCCTTTTATGTCCCCACCTTGAGGCCTTGCAGAGGCGCCTCTCAAGGCCCCATCAGCTCGCCG
GGACCTCTGTGAAGCCTCTCTGTCATCTCCCCTTCCCAGCCCCTCCTTCATCCCCTGCCTCCTTCACCAGCCTGGCTTTTGCCTGGAGCA
CTATTTGTTTAGTTCTCTTTGCAGGACAAGAATTCTCTCAGGGTGGTATCACCTCCTCCCTCCTCCCCACTCACTCCAGTTTTTAGCCCG
GAGCCTCCTGTGGTTGACTATCAGGAATGTGTGCTGTGTCAGGATACATAGGAAGTTGACCTCGGGGTATCATGGAGAGTGTCCCTCCTA
GTGGCTGGAGGTAGGGACAGTTGGTTGTGGGGCTGGAGAGAGGTTGTGGGGAGGAAGCGAGGATGCGTGCCTGCCACTAGGCATCTGCAT
CCCCGAGCCCAAGCCAGGAGGGATTTCCCTTAGGCAACACCATCCCAGGGAGATCTGCCACAATTTGCGTTTCACAGCTGAAGACGCTGA
GGCTTAGAGAGCTCGACCTCCTCAAGGTCACACCACTGGGTAAATAGAGGGATGCAGACTCAGGTTTTGCTATGTGCTCACATTTCAACT
TTATGCTTAACATGAATGGAAAAATATGAAAGTAAATAGTGAAAAGGTAAGTTATGAGCTTAGATTACCTAGATTATTCCAGTATCCCAT
GGAAGCTGAGGACTTATTCCGCTTTCCACACCGAACACTAAATGTGGACCAGTATCAAGAACCCTCCTGTCCCCACGCAGTGTAAACCCA
GTGGCTTCTCTGACCTGGAGCTGATGGGCCGTGAAGGGGGCCTATTTTTCTCCAAAGGCCATCCTTTTGGGGCCACCTGGCTCCAAGAAG
CATCGCTGGTCTTGGGGACGGGAAGGGAACCCTCTTCCAGGAGCTCTAAGGGTACTTGGGAATCAATTGTGTCCATTCTGAGGTCTCTCC
AGTGGGAGGGCGGCAGCTCCTGTCCCTGGGTTCAGGCTGTGCTTCTGGAAGCATCGAAATGGGATGTCTGAGCCTTGAGGAAAAGCAGCA
GGGTTAGCATTAAAGTCAAGAGGGGCAGCTCAGGATGCTACCAGGGAGCACATCGTTTCTGGTGCCTCATCTAAAGGTGAAACCTCCCCT
ACATTCACCAGCCGGATGTCCCAAATCCCTTTAGCCAGATTGCTTTTTGCAACCAAAGCTGTGGACAGAAAAGCCTCCTTAAGTGAGCTG
AGGGGACAGGAAATCCAATCAGATGACCTTTGTGTTCGTAATCGGGCTTGAGCCAGAGGCTGGGGAGCTGAGTCCCAGCCAAACCTCACT
GGCCCTTTTGCTTTTCACGCCCAGGGCTCAGTGGCCCAGGAAGTGTGCTGGGCAGCCTGTTCTTACTCCAGCTCAACCCATTGGGTGTTG
GCTGTTTTTGGTTTTAGTTGTTGTTTTGTATTTTGTTGTTTTAATTAATAGGCTTTATTTGTAAGAGCAGTTTTATGTTTACAGAAAAAT
TAGGCACAAAGGGATTCCCATATCCCTCCTCTTCTTTGCATATTTCCCCCTCTAATTAGCATGTTGCATTAGCATGGCACTTTGTTACAA

>4833_4833_1_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000265748_EEPD1_chr7_36320723_ENST00000242108_length(amino acids)=882AA_BP=623
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA
ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLN
KALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD
KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSA
EKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKV
EQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPEFCTELNQ
PTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAA
LTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKS

--------------------------------------------------------------
>4833_4833_2_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000265748_EEPD1_chr7_36320723_ENST00000534978_length(transcript)=3389nt_BP=2090nt
AGCGCGCATGCTCGCGGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAG
CTGGTTGTGGGAGAGTTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTG
AACCACCGTTTCCATCGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAG
AGAATCTTCAGAGAAAAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAG
CAAGTAACCAGCAGCCCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAG
TAGAAGTTTCTAACTTGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGC
CACAAGCAGCAGATACCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAA
CTGCAGCCTCCTCAGTTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGATGACATTCCTG
AAAGCTCACTCTTCTCACCAATGCCATCAGAGGAAAAGGCTGCTTCCCCTCCCAGACCTCTGCTTTCAAATGCCTCGGCAACTCCAGTTG
GCAGAAGGGGCCGTCTGGCCAATCTTGCTGCAACTATTTGCTCCTGGGAAGATGATGTAAATCACTCATTTGCAAAACAAAACAGTGTAC
AAGAACAGCCTGGTACCGCTTGTTTATCCAAATTTTCCTCTGCAAGTGGAGCATCTGCTAGGATCAATAGCAGCAGTGTTAAGCAGGAAG
CTACATTCTGTTCCCAAAGGGATGGCGATGCCTCTTTGAATAAAGCCCTATCCTCAAGTGCTGATGATGCGTCTTTGGTTAATGCCTCAA
TTTCCAGCTCTGTGAAAGCTACTTCTCCAGTGAAATCTACTACATCTATCACTGATGCTAAAAGTTGTGAGGGACAAAATCCTGAGCTAC
TTCCAAAAACTCCTATTAGTCCTCTGAAAACGGGGGTATCGAAACCAATTGTGAAGTCAACTTTATCCCAGACAGTTCCATCCAAGGGAG
AATTAAGTAGAGAAATTTGTCTGCAATCTCAATCTAAAGACAAATCTACGACACCAGGAGGAACAGGAATTAAGCCTTTCCTGGAACGCT
TTGGAGAGCGTTGTCAAGAACATAGCAAAGAAAGTCCAGCTCGTAGCACACCCCACAGAACCCCCATTATTACTCCAAATACAAAGGCCA
TCCAAGAAAGATTATTCAAGCAAGACACATCTTCATCTACTACCCATTTAGCACAACAGCTCAAGCAGGAACGTCAAAAAGAACTAGCAT
GTCTTCGTGGCCGATTTGACAAGGGCAATATATGGAGTGCAGAAAAAGGCGGAAACTCAAAAAGCAAACAACTAGAAACCAAACAGGAAA
CTCACTGTCAGAGCACTCCCCTCAAAAAACACCAAGGTGTTTCAAAAACTCAGTCACTTCCAGTAACAGAAAAGGTGACCGAAAACCAGA
TACCAGCCAAAAATTCTAGTACAGAACCTAAAGGTTTCACTGAATGCGAAATGACGAAATCTAGCCCTTTGAAAATAACATTGTTTTTAG
AAGAGGACAAATCCTTAAAAGTAACATCAGACCCAAAGGTTGAGCAGAAAATTGAAGTGATACGTGAAATTGAGATGAGTGTGGATGATG
ATGATATCAATAGTTCGAAAGTAATTAATGACCTCTTCAGTGATGTCCTAGAGGAAGGTGAACTAGATATGGAGAAGAGCCAAGAGGAGA
TGGATCAAGCATTAGCAGAAAGCAGCGAAGAACAGGAAGATGCACTGAATATCTCCTCAATGTCTTTACTTGCACCATTGGCACAAACAG
TTGGTGTGGTAAGTCCAGAGTTCTGCACGGAGCTAAACCAGCCGACCCTGCCCAACATCCGCAAGTGGAAGGGGCCCCGGGGATGCTGGA
AGGCTGTTGTTGCTGAGAAGCCCTCGAGTCAGCTCCAGAAGGGAGCTGGGTATGCAGGATTCCTATGGGACGCGGCTGCCGGCATGGAGC
TGAGAGACGCGGGTTCACAGGAGAGCTCGCCAAGCAACGGGCACGGGAAGCTGGCGGGCCCCAGCCCATACCTCGGGAGGTTCAAGGTGG
GAAGTCACGACCTGACCCTTGTTAACCTTCACCTGGCAGCCCTGACCCTCCTGGGGAGCGAGAATCCCAGCAAGAATCACAGTGATGGCC
ACCGGTTGGCGAGCTTTGCACAGACCCTACAGGAAACCCTGAAAGGAGAAAAGGATGTCATTATCTTAGGGGATTTTGGCCAAGGGCCAG
ACAGCAATGACTATGATATCCTGAGGAAAGAAAAGTTCCACCACCTGATCCCCGCGCACACCTTCACCAACATCAGCACCAAGAACCCTC
AAGGCTCGAAGTCTCTGGACAACATCTGGATCAGTAAAAGCTTAAAGAAGGTTTTCACAGGTCACTGGGCTGTGGTGAGAGAAGGCCTCA
CGAACCCTTGGATTCCGGATAACTGGTCTTGGGGCGGGGTGGCTTCTGAACACTGCCCAGTGCTAGCCGAGTTCTACACTGAAAAGGACT
GGAGCAAGAAGGATGCCCCTCGGAACGGCAGCGGGGTGGCCTTGGAGCGAAGTGAAGCCAACATCAAGCACGAGCGATGATGACACCAAA
TCCATGTGTCCACCCTGGGACCCAGGAGGGCACAGCCAAGGAATGAGCCCTGTGGGGTGACGCTTCAGGGCAGAGCTGCCTTTTAATTTT
TATTCTCAGAGCATCAGCACTTGAGGCCTTGCCCCACGCCTTCTCTGTGGACCATTCAGGACCTCCAGTGGGGGTGGCGTGCCAGGCGCG
TACCCCACCAGGTGGGCAAAGCAGAAACCTGCGGGGAGCGGAGACGCCTTTTATCTCTGGATGCCACAGACCTGAGCAGCATTGGGCTGG
CTGTCCGCTGCTGACTGGATGGCAGCACAAAGACAATATGAGCAGAGGGAGGAGAAGAAGGGGTGCTCAGGCTGCGGGCCACAGTCCAGC
AGCGCCAGAAGCACTCATTTCTGACCACCAGGCTATGACGTTCCTGCTGCGCATTACAGAAAGCTTTTAACTGTGATCAGGCACTCTGCT

>4833_4833_2_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000265748_EEPD1_chr7_36320723_ENST00000534978_length(amino acids)=882AA_BP=623
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA
ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLN
KALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD
KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSA
EKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKV
EQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPEFCTELNQ
PTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAA
LTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKS

--------------------------------------------------------------
>4833_4833_3_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000265748_EEPD1_chr7_36320724_ENST00000242108_length(transcript)=5207nt_BP=2090nt
AGCGCGCATGCTCGCGGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAG
CTGGTTGTGGGAGAGTTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTG
AACCACCGTTTCCATCGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAG
AGAATCTTCAGAGAAAAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAG
CAAGTAACCAGCAGCCCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAG
TAGAAGTTTCTAACTTGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGC
CACAAGCAGCAGATACCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAA
CTGCAGCCTCCTCAGTTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGATGACATTCCTG
AAAGCTCACTCTTCTCACCAATGCCATCAGAGGAAAAGGCTGCTTCCCCTCCCAGACCTCTGCTTTCAAATGCCTCGGCAACTCCAGTTG
GCAGAAGGGGCCGTCTGGCCAATCTTGCTGCAACTATTTGCTCCTGGGAAGATGATGTAAATCACTCATTTGCAAAACAAAACAGTGTAC
AAGAACAGCCTGGTACCGCTTGTTTATCCAAATTTTCCTCTGCAAGTGGAGCATCTGCTAGGATCAATAGCAGCAGTGTTAAGCAGGAAG
CTACATTCTGTTCCCAAAGGGATGGCGATGCCTCTTTGAATAAAGCCCTATCCTCAAGTGCTGATGATGCGTCTTTGGTTAATGCCTCAA
TTTCCAGCTCTGTGAAAGCTACTTCTCCAGTGAAATCTACTACATCTATCACTGATGCTAAAAGTTGTGAGGGACAAAATCCTGAGCTAC
TTCCAAAAACTCCTATTAGTCCTCTGAAAACGGGGGTATCGAAACCAATTGTGAAGTCAACTTTATCCCAGACAGTTCCATCCAAGGGAG
AATTAAGTAGAGAAATTTGTCTGCAATCTCAATCTAAAGACAAATCTACGACACCAGGAGGAACAGGAATTAAGCCTTTCCTGGAACGCT
TTGGAGAGCGTTGTCAAGAACATAGCAAAGAAAGTCCAGCTCGTAGCACACCCCACAGAACCCCCATTATTACTCCAAATACAAAGGCCA
TCCAAGAAAGATTATTCAAGCAAGACACATCTTCATCTACTACCCATTTAGCACAACAGCTCAAGCAGGAACGTCAAAAAGAACTAGCAT
GTCTTCGTGGCCGATTTGACAAGGGCAATATATGGAGTGCAGAAAAAGGCGGAAACTCAAAAAGCAAACAACTAGAAACCAAACAGGAAA
CTCACTGTCAGAGCACTCCCCTCAAAAAACACCAAGGTGTTTCAAAAACTCAGTCACTTCCAGTAACAGAAAAGGTGACCGAAAACCAGA
TACCAGCCAAAAATTCTAGTACAGAACCTAAAGGTTTCACTGAATGCGAAATGACGAAATCTAGCCCTTTGAAAATAACATTGTTTTTAG
AAGAGGACAAATCCTTAAAAGTAACATCAGACCCAAAGGTTGAGCAGAAAATTGAAGTGATACGTGAAATTGAGATGAGTGTGGATGATG
ATGATATCAATAGTTCGAAAGTAATTAATGACCTCTTCAGTGATGTCCTAGAGGAAGGTGAACTAGATATGGAGAAGAGCCAAGAGGAGA
TGGATCAAGCATTAGCAGAAAGCAGCGAAGAACAGGAAGATGCACTGAATATCTCCTCAATGTCTTTACTTGCACCATTGGCACAAACAG
TTGGTGTGGTAAGTCCAGAGTTCTGCACGGAGCTAAACCAGCCGACCCTGCCCAACATCCGCAAGTGGAAGGGGCCCCGGGGATGCTGGA
AGGCTGTTGTTGCTGAGAAGCCCTCGAGTCAGCTCCAGAAGGGAGCTGGGTATGCAGGATTCCTATGGGACGCGGCTGCCGGCATGGAGC
TGAGAGACGCGGGTTCACAGGAGAGCTCGCCAAGCAACGGGCACGGGAAGCTGGCGGGCCCCAGCCCATACCTCGGGAGGTTCAAGGTGG
GAAGTCACGACCTGACCCTTGTTAACCTTCACCTGGCAGCCCTGACCCTCCTGGGGAGCGAGAATCCCAGCAAGAATCACAGTGATGGCC
ACCGGTTGGCGAGCTTTGCACAGACCCTACAGGAAACCCTGAAAGGAGAAAAGGATGTCATTATCTTAGGGGATTTTGGCCAAGGGCCAG
ACAGCAATGACTATGATATCCTGAGGAAAGAAAAGTTCCACCACCTGATCCCCGCGCACACCTTCACCAACATCAGCACCAAGAACCCTC
AAGGCTCGAAGTCTCTGGACAACATCTGGATCAGTAAAAGCTTAAAGAAGGTTTTCACAGGTCACTGGGCTGTGGTGAGAGAAGGCCTCA
CGAACCCTTGGATTCCGGATAACTGGTCTTGGGGCGGGGTGGCTTCTGAACACTGCCCAGTGCTAGCCGAGTTCTACACTGAAAAGGACT
GGAGCAAGAAGGATGCCCCTCGGAACGGCAGCGGGGTGGCCTTGGAGCGAAGTGAAGCCAACATCAAGCACGAGCGATGATGACACCAAA
TCCATGTGTCCACCCTGGGACCCAGGAGGGCACAGCCAAGGAATGAGCCCTGTGGGGTGACGCTTCAGGGCAGAGCTGCCTTTTAATTTT
TATTCTCAGAGCATCAGCACTTGAGGCCTTGCCCCACGCCTTCTCTGTGGACCATTCAGGACCTCCAGTGGGGGTGGCGTGCCAGGCGCG
TACCCCACCAGGTGGGCAAAGCAGAAACCTGCGGGGAGCGGAGACGCCTTTTATCTCTGGATGCCACAGACCTGAGCAGCATTGGGCTGG
CTGTCCGCTGCTGACTGGATGGCAGCACAAAGACAATATGAGCAGAGGGAGGAGAAGAAGGGGTGCTCAGGCTGCGGGCCACAGTCCAGC
AGCGCCAGAAGCACTCATTTCTGACCACCAGGCTATGACGTTCCTGCTGCGCATTACAGAAAGCTTTTAACTGTGATCAGGCACTCTGCT
CAGATACATTGAGTGGCGATTTTTAGTTTTGTTTTGAAAAAATAAACAGATTAACCTGCCTCGCTGCAGTGAGAGCATGGGACAAGTCCG
CCACAGCCCTCCCCCGCCCCCTTCCCCCGCCCCCCAACGCGCAGTGTGTATTTGCACCACGGCAGGTGCCTCTGTGTGGAGCTAGGGTCA
AGCCCTGAGCAGCTTCACTTCCCCTGCGCCTTTTATGTCCCCACCTTGAGGCCTTGCAGAGGCGCCTCTCAAGGCCCCATCAGCTCGCCG
GGACCTCTGTGAAGCCTCTCTGTCATCTCCCCTTCCCAGCCCCTCCTTCATCCCCTGCCTCCTTCACCAGCCTGGCTTTTGCCTGGAGCA
CTATTTGTTTAGTTCTCTTTGCAGGACAAGAATTCTCTCAGGGTGGTATCACCTCCTCCCTCCTCCCCACTCACTCCAGTTTTTAGCCCG
GAGCCTCCTGTGGTTGACTATCAGGAATGTGTGCTGTGTCAGGATACATAGGAAGTTGACCTCGGGGTATCATGGAGAGTGTCCCTCCTA
GTGGCTGGAGGTAGGGACAGTTGGTTGTGGGGCTGGAGAGAGGTTGTGGGGAGGAAGCGAGGATGCGTGCCTGCCACTAGGCATCTGCAT
CCCCGAGCCCAAGCCAGGAGGGATTTCCCTTAGGCAACACCATCCCAGGGAGATCTGCCACAATTTGCGTTTCACAGCTGAAGACGCTGA
GGCTTAGAGAGCTCGACCTCCTCAAGGTCACACCACTGGGTAAATAGAGGGATGCAGACTCAGGTTTTGCTATGTGCTCACATTTCAACT
TTATGCTTAACATGAATGGAAAAATATGAAAGTAAATAGTGAAAAGGTAAGTTATGAGCTTAGATTACCTAGATTATTCCAGTATCCCAT
GGAAGCTGAGGACTTATTCCGCTTTCCACACCGAACACTAAATGTGGACCAGTATCAAGAACCCTCCTGTCCCCACGCAGTGTAAACCCA
GTGGCTTCTCTGACCTGGAGCTGATGGGCCGTGAAGGGGGCCTATTTTTCTCCAAAGGCCATCCTTTTGGGGCCACCTGGCTCCAAGAAG
CATCGCTGGTCTTGGGGACGGGAAGGGAACCCTCTTCCAGGAGCTCTAAGGGTACTTGGGAATCAATTGTGTCCATTCTGAGGTCTCTCC
AGTGGGAGGGCGGCAGCTCCTGTCCCTGGGTTCAGGCTGTGCTTCTGGAAGCATCGAAATGGGATGTCTGAGCCTTGAGGAAAAGCAGCA
GGGTTAGCATTAAAGTCAAGAGGGGCAGCTCAGGATGCTACCAGGGAGCACATCGTTTCTGGTGCCTCATCTAAAGGTGAAACCTCCCCT
ACATTCACCAGCCGGATGTCCCAAATCCCTTTAGCCAGATTGCTTTTTGCAACCAAAGCTGTGGACAGAAAAGCCTCCTTAAGTGAGCTG
AGGGGACAGGAAATCCAATCAGATGACCTTTGTGTTCGTAATCGGGCTTGAGCCAGAGGCTGGGGAGCTGAGTCCCAGCCAAACCTCACT
GGCCCTTTTGCTTTTCACGCCCAGGGCTCAGTGGCCCAGGAAGTGTGCTGGGCAGCCTGTTCTTACTCCAGCTCAACCCATTGGGTGTTG
GCTGTTTTTGGTTTTAGTTGTTGTTTTGTATTTTGTTGTTTTAATTAATAGGCTTTATTTGTAAGAGCAGTTTTATGTTTACAGAAAAAT
TAGGCACAAAGGGATTCCCATATCCCTCCTCTTCTTTGCATATTTCCCCCTCTAATTAGCATGTTGCATTAGCATGGCACTTTGTTACAA

>4833_4833_3_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000265748_EEPD1_chr7_36320724_ENST00000242108_length(amino acids)=882AA_BP=623
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA
ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLN
KALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD
KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSA
EKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKV
EQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPEFCTELNQ
PTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAA
LTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKS

--------------------------------------------------------------
>4833_4833_4_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000265748_EEPD1_chr7_36320724_ENST00000534978_length(transcript)=3389nt_BP=2090nt
AGCGCGCATGCTCGCGGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAG
CTGGTTGTGGGAGAGTTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTG
AACCACCGTTTCCATCGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAG
AGAATCTTCAGAGAAAAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAG
CAAGTAACCAGCAGCCCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAG
TAGAAGTTTCTAACTTGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGC
CACAAGCAGCAGATACCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAA
CTGCAGCCTCCTCAGTTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGATGACATTCCTG
AAAGCTCACTCTTCTCACCAATGCCATCAGAGGAAAAGGCTGCTTCCCCTCCCAGACCTCTGCTTTCAAATGCCTCGGCAACTCCAGTTG
GCAGAAGGGGCCGTCTGGCCAATCTTGCTGCAACTATTTGCTCCTGGGAAGATGATGTAAATCACTCATTTGCAAAACAAAACAGTGTAC
AAGAACAGCCTGGTACCGCTTGTTTATCCAAATTTTCCTCTGCAAGTGGAGCATCTGCTAGGATCAATAGCAGCAGTGTTAAGCAGGAAG
CTACATTCTGTTCCCAAAGGGATGGCGATGCCTCTTTGAATAAAGCCCTATCCTCAAGTGCTGATGATGCGTCTTTGGTTAATGCCTCAA
TTTCCAGCTCTGTGAAAGCTACTTCTCCAGTGAAATCTACTACATCTATCACTGATGCTAAAAGTTGTGAGGGACAAAATCCTGAGCTAC
TTCCAAAAACTCCTATTAGTCCTCTGAAAACGGGGGTATCGAAACCAATTGTGAAGTCAACTTTATCCCAGACAGTTCCATCCAAGGGAG
AATTAAGTAGAGAAATTTGTCTGCAATCTCAATCTAAAGACAAATCTACGACACCAGGAGGAACAGGAATTAAGCCTTTCCTGGAACGCT
TTGGAGAGCGTTGTCAAGAACATAGCAAAGAAAGTCCAGCTCGTAGCACACCCCACAGAACCCCCATTATTACTCCAAATACAAAGGCCA
TCCAAGAAAGATTATTCAAGCAAGACACATCTTCATCTACTACCCATTTAGCACAACAGCTCAAGCAGGAACGTCAAAAAGAACTAGCAT
GTCTTCGTGGCCGATTTGACAAGGGCAATATATGGAGTGCAGAAAAAGGCGGAAACTCAAAAAGCAAACAACTAGAAACCAAACAGGAAA
CTCACTGTCAGAGCACTCCCCTCAAAAAACACCAAGGTGTTTCAAAAACTCAGTCACTTCCAGTAACAGAAAAGGTGACCGAAAACCAGA
TACCAGCCAAAAATTCTAGTACAGAACCTAAAGGTTTCACTGAATGCGAAATGACGAAATCTAGCCCTTTGAAAATAACATTGTTTTTAG
AAGAGGACAAATCCTTAAAAGTAACATCAGACCCAAAGGTTGAGCAGAAAATTGAAGTGATACGTGAAATTGAGATGAGTGTGGATGATG
ATGATATCAATAGTTCGAAAGTAATTAATGACCTCTTCAGTGATGTCCTAGAGGAAGGTGAACTAGATATGGAGAAGAGCCAAGAGGAGA
TGGATCAAGCATTAGCAGAAAGCAGCGAAGAACAGGAAGATGCACTGAATATCTCCTCAATGTCTTTACTTGCACCATTGGCACAAACAG
TTGGTGTGGTAAGTCCAGAGTTCTGCACGGAGCTAAACCAGCCGACCCTGCCCAACATCCGCAAGTGGAAGGGGCCCCGGGGATGCTGGA
AGGCTGTTGTTGCTGAGAAGCCCTCGAGTCAGCTCCAGAAGGGAGCTGGGTATGCAGGATTCCTATGGGACGCGGCTGCCGGCATGGAGC
TGAGAGACGCGGGTTCACAGGAGAGCTCGCCAAGCAACGGGCACGGGAAGCTGGCGGGCCCCAGCCCATACCTCGGGAGGTTCAAGGTGG
GAAGTCACGACCTGACCCTTGTTAACCTTCACCTGGCAGCCCTGACCCTCCTGGGGAGCGAGAATCCCAGCAAGAATCACAGTGATGGCC
ACCGGTTGGCGAGCTTTGCACAGACCCTACAGGAAACCCTGAAAGGAGAAAAGGATGTCATTATCTTAGGGGATTTTGGCCAAGGGCCAG
ACAGCAATGACTATGATATCCTGAGGAAAGAAAAGTTCCACCACCTGATCCCCGCGCACACCTTCACCAACATCAGCACCAAGAACCCTC
AAGGCTCGAAGTCTCTGGACAACATCTGGATCAGTAAAAGCTTAAAGAAGGTTTTCACAGGTCACTGGGCTGTGGTGAGAGAAGGCCTCA
CGAACCCTTGGATTCCGGATAACTGGTCTTGGGGCGGGGTGGCTTCTGAACACTGCCCAGTGCTAGCCGAGTTCTACACTGAAAAGGACT
GGAGCAAGAAGGATGCCCCTCGGAACGGCAGCGGGGTGGCCTTGGAGCGAAGTGAAGCCAACATCAAGCACGAGCGATGATGACACCAAA
TCCATGTGTCCACCCTGGGACCCAGGAGGGCACAGCCAAGGAATGAGCCCTGTGGGGTGACGCTTCAGGGCAGAGCTGCCTTTTAATTTT
TATTCTCAGAGCATCAGCACTTGAGGCCTTGCCCCACGCCTTCTCTGTGGACCATTCAGGACCTCCAGTGGGGGTGGCGTGCCAGGCGCG
TACCCCACCAGGTGGGCAAAGCAGAAACCTGCGGGGAGCGGAGACGCCTTTTATCTCTGGATGCCACAGACCTGAGCAGCATTGGGCTGG
CTGTCCGCTGCTGACTGGATGGCAGCACAAAGACAATATGAGCAGAGGGAGGAGAAGAAGGGGTGCTCAGGCTGCGGGCCACAGTCCAGC
AGCGCCAGAAGCACTCATTTCTGACCACCAGGCTATGACGTTCCTGCTGCGCATTACAGAAAGCTTTTAACTGTGATCAGGCACTCTGCT

>4833_4833_4_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000265748_EEPD1_chr7_36320724_ENST00000534978_length(amino acids)=882AA_BP=623
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA
ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLN
KALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD
KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSA
EKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSSPLKITLFLEEDKSLKVTSDPKV
EQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEGELDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPEFCTELNQ
PTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGFLWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAA
LTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVIILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKS

--------------------------------------------------------------
>4833_4833_5_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000396068_EEPD1_chr7_36320723_ENST00000242108_length(transcript)=5081nt_BP=1964nt
GGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAGCTGGTTGTGGGAGAG
TTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTGAACCACCGTTTCCAT
CGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAGAGAATCTTCAGAGAA
AAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAGCAAGTAACCAGCAGC
CCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAGTAGAAGTTTCTAACT
TGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGCCACAAGCAGCAGATA
CCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAACTGCAGCCTCCTCAG
TTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGATGACATTCCTGAAAGCTCACTCTTCT
CACCAATGCCATCAGAGGAAAAGGCTGCTTCCCCTCCCAGACCTCTGCTTTCAAATGCCTCGGCAACTCCAGTTGGCAGAAGGGGCCGTC
TGGCCAATCTTGCTGCAACTATTTGCTCCTGGGAAGATGATGTAAATCACTCATTTGCAAAACAAAACAGTGTACAAGAACAGCCTGGTA
CCGCTTGTTTATCCAAATTTTCCTCTGCAAGTGGAGCATCTGCTAGGATCAATAGCAGCAGTGTTAAGCAGGAAGCTACATTCTGTTCCC
AAAGGGATGGCGATGCCTCTTTGAATAAAGCCCTATCCTCAAGTGCTGATGATGCGTCTTTGGTTAATGCCTCAATTTCCAGCTCTGTGA
AAGCTACTTCTCCAGTGAAATCTACTACATCTATCACTGATGCTAAAAGTTGTGAGGGACAAAATCCTGAGCTACTTCCAAAAACTCCTA
TTAGTCCTCTGAAAACGGGGGTATCGAAACCAATTGTGAAGTCAACTTTATCCCAGACAGTTCCATCCAAGGGAGAATTAAGTAGAGAAA
TTTGTCTGCAATCTCAATCTAAAGACAAATCTACGACACCAGGAGGAACAGGAATTAAGCCTTTCCTGGAACGCTTTGGAGAGCGTTGTC
AAGAACATAGCAAAGAAAGTCCAGCTCGTAGCACACCCCACAGAACCCCCATTATTACTCCAAATACAAAGGCCATCCAAGAAAGATTAT
TCAAGCAAGACACATCTTCATCTACTACCCATTTAGCACAACAGCTCAAGCAGGAACGTCAAAAAGAACTAGCATGTCTTCGTGGCCGAT
TTGACAAGGGCAATATATGGAGTGCAGAAAAAGGCGGAAACTCAAAAAGCAAACAACTAGAAACCAAACAGGAAACTCACTGTCAGAGCA
CTCCCCTCAAAAAACACCAAGGTGTTTCAAAAACTCAGTCACTTCCAGTAACAGAAAAGGTGACCGAAAACCAGATACCAGCCAAAAATT
CTAGTACAGAACCTAAAGAAGTGATACGTGAAATTGAGATGAGTGTGGATGATGATGATATCAATAGTTCGAAAGTAATTAATGACCTCT
TCAGTGATGTCCTAGAGGAAGGTGAACTAGATATGGAGAAGAGCCAAGAGGAGATGGATCAAGCATTAGCAGAAAGCAGCGAAGAACAGG
AAGATGCACTGAATATCTCCTCAATGTCTTTACTTGCACCATTGGCACAAACAGTTGGTGTGGTAAGTCCAGAGTTCTGCACGGAGCTAA
ACCAGCCGACCCTGCCCAACATCCGCAAGTGGAAGGGGCCCCGGGGATGCTGGAAGGCTGTTGTTGCTGAGAAGCCCTCGAGTCAGCTCC
AGAAGGGAGCTGGGTATGCAGGATTCCTATGGGACGCGGCTGCCGGCATGGAGCTGAGAGACGCGGGTTCACAGGAGAGCTCGCCAAGCA
ACGGGCACGGGAAGCTGGCGGGCCCCAGCCCATACCTCGGGAGGTTCAAGGTGGGAAGTCACGACCTGACCCTTGTTAACCTTCACCTGG
CAGCCCTGACCCTCCTGGGGAGCGAGAATCCCAGCAAGAATCACAGTGATGGCCACCGGTTGGCGAGCTTTGCACAGACCCTACAGGAAA
CCCTGAAAGGAGAAAAGGATGTCATTATCTTAGGGGATTTTGGCCAAGGGCCAGACAGCAATGACTATGATATCCTGAGGAAAGAAAAGT
TCCACCACCTGATCCCCGCGCACACCTTCACCAACATCAGCACCAAGAACCCTCAAGGCTCGAAGTCTCTGGACAACATCTGGATCAGTA
AAAGCTTAAAGAAGGTTTTCACAGGTCACTGGGCTGTGGTGAGAGAAGGCCTCACGAACCCTTGGATTCCGGATAACTGGTCTTGGGGCG
GGGTGGCTTCTGAACACTGCCCAGTGCTAGCCGAGTTCTACACTGAAAAGGACTGGAGCAAGAAGGATGCCCCTCGGAACGGCAGCGGGG
TGGCCTTGGAGCGAAGTGAAGCCAACATCAAGCACGAGCGATGATGACACCAAATCCATGTGTCCACCCTGGGACCCAGGAGGGCACAGC
CAAGGAATGAGCCCTGTGGGGTGACGCTTCAGGGCAGAGCTGCCTTTTAATTTTTATTCTCAGAGCATCAGCACTTGAGGCCTTGCCCCA
CGCCTTCTCTGTGGACCATTCAGGACCTCCAGTGGGGGTGGCGTGCCAGGCGCGTACCCCACCAGGTGGGCAAAGCAGAAACCTGCGGGG
AGCGGAGACGCCTTTTATCTCTGGATGCCACAGACCTGAGCAGCATTGGGCTGGCTGTCCGCTGCTGACTGGATGGCAGCACAAAGACAA
TATGAGCAGAGGGAGGAGAAGAAGGGGTGCTCAGGCTGCGGGCCACAGTCCAGCAGCGCCAGAAGCACTCATTTCTGACCACCAGGCTAT
GACGTTCCTGCTGCGCATTACAGAAAGCTTTTAACTGTGATCAGGCACTCTGCTCAGATACATTGAGTGGCGATTTTTAGTTTTGTTTTG
AAAAAATAAACAGATTAACCTGCCTCGCTGCAGTGAGAGCATGGGACAAGTCCGCCACAGCCCTCCCCCGCCCCCTTCCCCCGCCCCCCA
ACGCGCAGTGTGTATTTGCACCACGGCAGGTGCCTCTGTGTGGAGCTAGGGTCAAGCCCTGAGCAGCTTCACTTCCCCTGCGCCTTTTAT
GTCCCCACCTTGAGGCCTTGCAGAGGCGCCTCTCAAGGCCCCATCAGCTCGCCGGGACCTCTGTGAAGCCTCTCTGTCATCTCCCCTTCC
CAGCCCCTCCTTCATCCCCTGCCTCCTTCACCAGCCTGGCTTTTGCCTGGAGCACTATTTGTTTAGTTCTCTTTGCAGGACAAGAATTCT
CTCAGGGTGGTATCACCTCCTCCCTCCTCCCCACTCACTCCAGTTTTTAGCCCGGAGCCTCCTGTGGTTGACTATCAGGAATGTGTGCTG
TGTCAGGATACATAGGAAGTTGACCTCGGGGTATCATGGAGAGTGTCCCTCCTAGTGGCTGGAGGTAGGGACAGTTGGTTGTGGGGCTGG
AGAGAGGTTGTGGGGAGGAAGCGAGGATGCGTGCCTGCCACTAGGCATCTGCATCCCCGAGCCCAAGCCAGGAGGGATTTCCCTTAGGCA
ACACCATCCCAGGGAGATCTGCCACAATTTGCGTTTCACAGCTGAAGACGCTGAGGCTTAGAGAGCTCGACCTCCTCAAGGTCACACCAC
TGGGTAAATAGAGGGATGCAGACTCAGGTTTTGCTATGTGCTCACATTTCAACTTTATGCTTAACATGAATGGAAAAATATGAAAGTAAA
TAGTGAAAAGGTAAGTTATGAGCTTAGATTACCTAGATTATTCCAGTATCCCATGGAAGCTGAGGACTTATTCCGCTTTCCACACCGAAC
ACTAAATGTGGACCAGTATCAAGAACCCTCCTGTCCCCACGCAGTGTAAACCCAGTGGCTTCTCTGACCTGGAGCTGATGGGCCGTGAAG
GGGGCCTATTTTTCTCCAAAGGCCATCCTTTTGGGGCCACCTGGCTCCAAGAAGCATCGCTGGTCTTGGGGACGGGAAGGGAACCCTCTT
CCAGGAGCTCTAAGGGTACTTGGGAATCAATTGTGTCCATTCTGAGGTCTCTCCAGTGGGAGGGCGGCAGCTCCTGTCCCTGGGTTCAGG
CTGTGCTTCTGGAAGCATCGAAATGGGATGTCTGAGCCTTGAGGAAAAGCAGCAGGGTTAGCATTAAAGTCAAGAGGGGCAGCTCAGGAT
GCTACCAGGGAGCACATCGTTTCTGGTGCCTCATCTAAAGGTGAAACCTCCCCTACATTCACCAGCCGGATGTCCCAAATCCCTTTAGCC
AGATTGCTTTTTGCAACCAAAGCTGTGGACAGAAAAGCCTCCTTAAGTGAGCTGAGGGGACAGGAAATCCAATCAGATGACCTTTGTGTT
CGTAATCGGGCTTGAGCCAGAGGCTGGGGAGCTGAGTCCCAGCCAAACCTCACTGGCCCTTTTGCTTTTCACGCCCAGGGCTCAGTGGCC
CAGGAAGTGTGCTGGGCAGCCTGTTCTTACTCCAGCTCAACCCATTGGGTGTTGGCTGTTTTTGGTTTTAGTTGTTGTTTTGTATTTTGT
TGTTTTAATTAATAGGCTTTATTTGTAAGAGCAGTTTTATGTTTACAGAAAAATTAGGCACAAAGGGATTCCCATATCCCTCCTCTTCTT
TGCATATTTCCCCCTCTAATTAGCATGTTGCATTAGCATGGCACTTTGTTACAACTGATGAACTTGTATTCATTATTAGCTACAGTGTTC

>4833_4833_5_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000396068_EEPD1_chr7_36320723_ENST00000242108_length(amino acids)=845AA_BP=586
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA
ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLN
KALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD
KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSA
EKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKEVIREIEMSVDDDDINSSKVINDLFSDVLEEGE
LDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPEFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGF
LWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVI
ILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPV

--------------------------------------------------------------
>4833_4833_6_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000396068_EEPD1_chr7_36320723_ENST00000534978_length(transcript)=3263nt_BP=1964nt
GGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAGCTGGTTGTGGGAGAG
TTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTGAACCACCGTTTCCAT
CGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAGAGAATCTTCAGAGAA
AAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAGCAAGTAACCAGCAGC
CCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAGTAGAAGTTTCTAACT
TGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGCCACAAGCAGCAGATA
CCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAACTGCAGCCTCCTCAG
TTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGATGACATTCCTGAAAGCTCACTCTTCT
CACCAATGCCATCAGAGGAAAAGGCTGCTTCCCCTCCCAGACCTCTGCTTTCAAATGCCTCGGCAACTCCAGTTGGCAGAAGGGGCCGTC
TGGCCAATCTTGCTGCAACTATTTGCTCCTGGGAAGATGATGTAAATCACTCATTTGCAAAACAAAACAGTGTACAAGAACAGCCTGGTA
CCGCTTGTTTATCCAAATTTTCCTCTGCAAGTGGAGCATCTGCTAGGATCAATAGCAGCAGTGTTAAGCAGGAAGCTACATTCTGTTCCC
AAAGGGATGGCGATGCCTCTTTGAATAAAGCCCTATCCTCAAGTGCTGATGATGCGTCTTTGGTTAATGCCTCAATTTCCAGCTCTGTGA
AAGCTACTTCTCCAGTGAAATCTACTACATCTATCACTGATGCTAAAAGTTGTGAGGGACAAAATCCTGAGCTACTTCCAAAAACTCCTA
TTAGTCCTCTGAAAACGGGGGTATCGAAACCAATTGTGAAGTCAACTTTATCCCAGACAGTTCCATCCAAGGGAGAATTAAGTAGAGAAA
TTTGTCTGCAATCTCAATCTAAAGACAAATCTACGACACCAGGAGGAACAGGAATTAAGCCTTTCCTGGAACGCTTTGGAGAGCGTTGTC
AAGAACATAGCAAAGAAAGTCCAGCTCGTAGCACACCCCACAGAACCCCCATTATTACTCCAAATACAAAGGCCATCCAAGAAAGATTAT
TCAAGCAAGACACATCTTCATCTACTACCCATTTAGCACAACAGCTCAAGCAGGAACGTCAAAAAGAACTAGCATGTCTTCGTGGCCGAT
TTGACAAGGGCAATATATGGAGTGCAGAAAAAGGCGGAAACTCAAAAAGCAAACAACTAGAAACCAAACAGGAAACTCACTGTCAGAGCA
CTCCCCTCAAAAAACACCAAGGTGTTTCAAAAACTCAGTCACTTCCAGTAACAGAAAAGGTGACCGAAAACCAGATACCAGCCAAAAATT
CTAGTACAGAACCTAAAGAAGTGATACGTGAAATTGAGATGAGTGTGGATGATGATGATATCAATAGTTCGAAAGTAATTAATGACCTCT
TCAGTGATGTCCTAGAGGAAGGTGAACTAGATATGGAGAAGAGCCAAGAGGAGATGGATCAAGCATTAGCAGAAAGCAGCGAAGAACAGG
AAGATGCACTGAATATCTCCTCAATGTCTTTACTTGCACCATTGGCACAAACAGTTGGTGTGGTAAGTCCAGAGTTCTGCACGGAGCTAA
ACCAGCCGACCCTGCCCAACATCCGCAAGTGGAAGGGGCCCCGGGGATGCTGGAAGGCTGTTGTTGCTGAGAAGCCCTCGAGTCAGCTCC
AGAAGGGAGCTGGGTATGCAGGATTCCTATGGGACGCGGCTGCCGGCATGGAGCTGAGAGACGCGGGTTCACAGGAGAGCTCGCCAAGCA
ACGGGCACGGGAAGCTGGCGGGCCCCAGCCCATACCTCGGGAGGTTCAAGGTGGGAAGTCACGACCTGACCCTTGTTAACCTTCACCTGG
CAGCCCTGACCCTCCTGGGGAGCGAGAATCCCAGCAAGAATCACAGTGATGGCCACCGGTTGGCGAGCTTTGCACAGACCCTACAGGAAA
CCCTGAAAGGAGAAAAGGATGTCATTATCTTAGGGGATTTTGGCCAAGGGCCAGACAGCAATGACTATGATATCCTGAGGAAAGAAAAGT
TCCACCACCTGATCCCCGCGCACACCTTCACCAACATCAGCACCAAGAACCCTCAAGGCTCGAAGTCTCTGGACAACATCTGGATCAGTA
AAAGCTTAAAGAAGGTTTTCACAGGTCACTGGGCTGTGGTGAGAGAAGGCCTCACGAACCCTTGGATTCCGGATAACTGGTCTTGGGGCG
GGGTGGCTTCTGAACACTGCCCAGTGCTAGCCGAGTTCTACACTGAAAAGGACTGGAGCAAGAAGGATGCCCCTCGGAACGGCAGCGGGG
TGGCCTTGGAGCGAAGTGAAGCCAACATCAAGCACGAGCGATGATGACACCAAATCCATGTGTCCACCCTGGGACCCAGGAGGGCACAGC
CAAGGAATGAGCCCTGTGGGGTGACGCTTCAGGGCAGAGCTGCCTTTTAATTTTTATTCTCAGAGCATCAGCACTTGAGGCCTTGCCCCA
CGCCTTCTCTGTGGACCATTCAGGACCTCCAGTGGGGGTGGCGTGCCAGGCGCGTACCCCACCAGGTGGGCAAAGCAGAAACCTGCGGGG
AGCGGAGACGCCTTTTATCTCTGGATGCCACAGACCTGAGCAGCATTGGGCTGGCTGTCCGCTGCTGACTGGATGGCAGCACAAAGACAA
TATGAGCAGAGGGAGGAGAAGAAGGGGTGCTCAGGCTGCGGGCCACAGTCCAGCAGCGCCAGAAGCACTCATTTCTGACCACCAGGCTAT
GACGTTCCTGCTGCGCATTACAGAAAGCTTTTAACTGTGATCAGGCACTCTGCTCAGATACATTGAGTGGCGATTTTTAGTTTTGTTTTG

>4833_4833_6_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000396068_EEPD1_chr7_36320723_ENST00000534978_length(amino acids)=845AA_BP=586
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA
ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLN
KALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD
KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSA
EKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKEVIREIEMSVDDDDINSSKVINDLFSDVLEEGE
LDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPEFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGF
LWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVI
ILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPV

--------------------------------------------------------------
>4833_4833_7_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000396068_EEPD1_chr7_36320724_ENST00000242108_length(transcript)=5081nt_BP=1964nt
GGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAGCTGGTTGTGGGAGAG
TTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTGAACCACCGTTTCCAT
CGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAGAGAATCTTCAGAGAA
AAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAGCAAGTAACCAGCAGC
CCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAGTAGAAGTTTCTAACT
TGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGCCACAAGCAGCAGATA
CCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAACTGCAGCCTCCTCAG
TTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGATGACATTCCTGAAAGCTCACTCTTCT
CACCAATGCCATCAGAGGAAAAGGCTGCTTCCCCTCCCAGACCTCTGCTTTCAAATGCCTCGGCAACTCCAGTTGGCAGAAGGGGCCGTC
TGGCCAATCTTGCTGCAACTATTTGCTCCTGGGAAGATGATGTAAATCACTCATTTGCAAAACAAAACAGTGTACAAGAACAGCCTGGTA
CCGCTTGTTTATCCAAATTTTCCTCTGCAAGTGGAGCATCTGCTAGGATCAATAGCAGCAGTGTTAAGCAGGAAGCTACATTCTGTTCCC
AAAGGGATGGCGATGCCTCTTTGAATAAAGCCCTATCCTCAAGTGCTGATGATGCGTCTTTGGTTAATGCCTCAATTTCCAGCTCTGTGA
AAGCTACTTCTCCAGTGAAATCTACTACATCTATCACTGATGCTAAAAGTTGTGAGGGACAAAATCCTGAGCTACTTCCAAAAACTCCTA
TTAGTCCTCTGAAAACGGGGGTATCGAAACCAATTGTGAAGTCAACTTTATCCCAGACAGTTCCATCCAAGGGAGAATTAAGTAGAGAAA
TTTGTCTGCAATCTCAATCTAAAGACAAATCTACGACACCAGGAGGAACAGGAATTAAGCCTTTCCTGGAACGCTTTGGAGAGCGTTGTC
AAGAACATAGCAAAGAAAGTCCAGCTCGTAGCACACCCCACAGAACCCCCATTATTACTCCAAATACAAAGGCCATCCAAGAAAGATTAT
TCAAGCAAGACACATCTTCATCTACTACCCATTTAGCACAACAGCTCAAGCAGGAACGTCAAAAAGAACTAGCATGTCTTCGTGGCCGAT
TTGACAAGGGCAATATATGGAGTGCAGAAAAAGGCGGAAACTCAAAAAGCAAACAACTAGAAACCAAACAGGAAACTCACTGTCAGAGCA
CTCCCCTCAAAAAACACCAAGGTGTTTCAAAAACTCAGTCACTTCCAGTAACAGAAAAGGTGACCGAAAACCAGATACCAGCCAAAAATT
CTAGTACAGAACCTAAAGAAGTGATACGTGAAATTGAGATGAGTGTGGATGATGATGATATCAATAGTTCGAAAGTAATTAATGACCTCT
TCAGTGATGTCCTAGAGGAAGGTGAACTAGATATGGAGAAGAGCCAAGAGGAGATGGATCAAGCATTAGCAGAAAGCAGCGAAGAACAGG
AAGATGCACTGAATATCTCCTCAATGTCTTTACTTGCACCATTGGCACAAACAGTTGGTGTGGTAAGTCCAGAGTTCTGCACGGAGCTAA
ACCAGCCGACCCTGCCCAACATCCGCAAGTGGAAGGGGCCCCGGGGATGCTGGAAGGCTGTTGTTGCTGAGAAGCCCTCGAGTCAGCTCC
AGAAGGGAGCTGGGTATGCAGGATTCCTATGGGACGCGGCTGCCGGCATGGAGCTGAGAGACGCGGGTTCACAGGAGAGCTCGCCAAGCA
ACGGGCACGGGAAGCTGGCGGGCCCCAGCCCATACCTCGGGAGGTTCAAGGTGGGAAGTCACGACCTGACCCTTGTTAACCTTCACCTGG
CAGCCCTGACCCTCCTGGGGAGCGAGAATCCCAGCAAGAATCACAGTGATGGCCACCGGTTGGCGAGCTTTGCACAGACCCTACAGGAAA
CCCTGAAAGGAGAAAAGGATGTCATTATCTTAGGGGATTTTGGCCAAGGGCCAGACAGCAATGACTATGATATCCTGAGGAAAGAAAAGT
TCCACCACCTGATCCCCGCGCACACCTTCACCAACATCAGCACCAAGAACCCTCAAGGCTCGAAGTCTCTGGACAACATCTGGATCAGTA
AAAGCTTAAAGAAGGTTTTCACAGGTCACTGGGCTGTGGTGAGAGAAGGCCTCACGAACCCTTGGATTCCGGATAACTGGTCTTGGGGCG
GGGTGGCTTCTGAACACTGCCCAGTGCTAGCCGAGTTCTACACTGAAAAGGACTGGAGCAAGAAGGATGCCCCTCGGAACGGCAGCGGGG
TGGCCTTGGAGCGAAGTGAAGCCAACATCAAGCACGAGCGATGATGACACCAAATCCATGTGTCCACCCTGGGACCCAGGAGGGCACAGC
CAAGGAATGAGCCCTGTGGGGTGACGCTTCAGGGCAGAGCTGCCTTTTAATTTTTATTCTCAGAGCATCAGCACTTGAGGCCTTGCCCCA
CGCCTTCTCTGTGGACCATTCAGGACCTCCAGTGGGGGTGGCGTGCCAGGCGCGTACCCCACCAGGTGGGCAAAGCAGAAACCTGCGGGG
AGCGGAGACGCCTTTTATCTCTGGATGCCACAGACCTGAGCAGCATTGGGCTGGCTGTCCGCTGCTGACTGGATGGCAGCACAAAGACAA
TATGAGCAGAGGGAGGAGAAGAAGGGGTGCTCAGGCTGCGGGCCACAGTCCAGCAGCGCCAGAAGCACTCATTTCTGACCACCAGGCTAT
GACGTTCCTGCTGCGCATTACAGAAAGCTTTTAACTGTGATCAGGCACTCTGCTCAGATACATTGAGTGGCGATTTTTAGTTTTGTTTTG
AAAAAATAAACAGATTAACCTGCCTCGCTGCAGTGAGAGCATGGGACAAGTCCGCCACAGCCCTCCCCCGCCCCCTTCCCCCGCCCCCCA
ACGCGCAGTGTGTATTTGCACCACGGCAGGTGCCTCTGTGTGGAGCTAGGGTCAAGCCCTGAGCAGCTTCACTTCCCCTGCGCCTTTTAT
GTCCCCACCTTGAGGCCTTGCAGAGGCGCCTCTCAAGGCCCCATCAGCTCGCCGGGACCTCTGTGAAGCCTCTCTGTCATCTCCCCTTCC
CAGCCCCTCCTTCATCCCCTGCCTCCTTCACCAGCCTGGCTTTTGCCTGGAGCACTATTTGTTTAGTTCTCTTTGCAGGACAAGAATTCT
CTCAGGGTGGTATCACCTCCTCCCTCCTCCCCACTCACTCCAGTTTTTAGCCCGGAGCCTCCTGTGGTTGACTATCAGGAATGTGTGCTG
TGTCAGGATACATAGGAAGTTGACCTCGGGGTATCATGGAGAGTGTCCCTCCTAGTGGCTGGAGGTAGGGACAGTTGGTTGTGGGGCTGG
AGAGAGGTTGTGGGGAGGAAGCGAGGATGCGTGCCTGCCACTAGGCATCTGCATCCCCGAGCCCAAGCCAGGAGGGATTTCCCTTAGGCA
ACACCATCCCAGGGAGATCTGCCACAATTTGCGTTTCACAGCTGAAGACGCTGAGGCTTAGAGAGCTCGACCTCCTCAAGGTCACACCAC
TGGGTAAATAGAGGGATGCAGACTCAGGTTTTGCTATGTGCTCACATTTCAACTTTATGCTTAACATGAATGGAAAAATATGAAAGTAAA
TAGTGAAAAGGTAAGTTATGAGCTTAGATTACCTAGATTATTCCAGTATCCCATGGAAGCTGAGGACTTATTCCGCTTTCCACACCGAAC
ACTAAATGTGGACCAGTATCAAGAACCCTCCTGTCCCCACGCAGTGTAAACCCAGTGGCTTCTCTGACCTGGAGCTGATGGGCCGTGAAG
GGGGCCTATTTTTCTCCAAAGGCCATCCTTTTGGGGCCACCTGGCTCCAAGAAGCATCGCTGGTCTTGGGGACGGGAAGGGAACCCTCTT
CCAGGAGCTCTAAGGGTACTTGGGAATCAATTGTGTCCATTCTGAGGTCTCTCCAGTGGGAGGGCGGCAGCTCCTGTCCCTGGGTTCAGG
CTGTGCTTCTGGAAGCATCGAAATGGGATGTCTGAGCCTTGAGGAAAAGCAGCAGGGTTAGCATTAAAGTCAAGAGGGGCAGCTCAGGAT
GCTACCAGGGAGCACATCGTTTCTGGTGCCTCATCTAAAGGTGAAACCTCCCCTACATTCACCAGCCGGATGTCCCAAATCCCTTTAGCC
AGATTGCTTTTTGCAACCAAAGCTGTGGACAGAAAAGCCTCCTTAAGTGAGCTGAGGGGACAGGAAATCCAATCAGATGACCTTTGTGTT
CGTAATCGGGCTTGAGCCAGAGGCTGGGGAGCTGAGTCCCAGCCAAACCTCACTGGCCCTTTTGCTTTTCACGCCCAGGGCTCAGTGGCC
CAGGAAGTGTGCTGGGCAGCCTGTTCTTACTCCAGCTCAACCCATTGGGTGTTGGCTGTTTTTGGTTTTAGTTGTTGTTTTGTATTTTGT
TGTTTTAATTAATAGGCTTTATTTGTAAGAGCAGTTTTATGTTTACAGAAAAATTAGGCACAAAGGGATTCCCATATCCCTCCTCTTCTT
TGCATATTTCCCCCTCTAATTAGCATGTTGCATTAGCATGGCACTTTGTTACAACTGATGAACTTGTATTCATTATTAGCTACAGTGTTC

>4833_4833_7_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000396068_EEPD1_chr7_36320724_ENST00000242108_length(amino acids)=845AA_BP=586
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA
ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLN
KALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD
KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSA
EKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKEVIREIEMSVDDDDINSSKVINDLFSDVLEEGE
LDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPEFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGF
LWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVI
ILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPV

--------------------------------------------------------------
>4833_4833_8_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000396068_EEPD1_chr7_36320724_ENST00000534978_length(transcript)=3263nt_BP=1964nt
GGCTCGGCGCTGAAATTCAAATTTGAACGGCTGCAGAGGCCGAGTCCGTCACTGGAAGCCGAGAGGAGAGGACAGCTGGTTGTGGGAGAG
TTCCCCCGCCTCAGACTCCTGGTTTTTTCCAGGAGACACACTGAGCTGAGACTCACTTTTCTCTTCCTGAATTTGAACCACCGTTTCCAT
CGTCTCGTAGTCCGACGCCTGGGGCGATGGATCCGTTTACGGAGAAACTGCTGGAGCGAACCCGTGCCAGGCGAGAGAATCTTCAGAGAA
AAATGGCTGAGAGGCCCACAGCAGCTCCAAGGTCTATGACTCATGCTAAGCGAGCTAGACAGCCACTTTCAGAAGCAAGTAACCAGCAGC
CCCTCTCTGGTGGTGAAGAGAAATCTTGTACAAAACCATCGCCATCAAAAAAACGCTGTTCTGACAACACTGAAGTAGAAGTTTCTAACT
TGGAAAATAAACAACCAGTTGAGTCGACATCTGCAAAATCTTGTTCTCCAAGTCCTGTGTCTCCTCAGGTGCAGCCACAAGCAGCAGATA
CCATCAGTGATTCTGTTGCTGTCCCGGCATCACTGCTGGGCATGAGGAGAGGGCTGAACTCAAGATTGGAAGCAACTGCAGCCTCCTCAG
TTAAAACACGTATGCAAAAACTTGCAGAGCAACGGCGCCGTTGGGATAATGATGATATGACAGATGACATTCCTGAAAGCTCACTCTTCT
CACCAATGCCATCAGAGGAAAAGGCTGCTTCCCCTCCCAGACCTCTGCTTTCAAATGCCTCGGCAACTCCAGTTGGCAGAAGGGGCCGTC
TGGCCAATCTTGCTGCAACTATTTGCTCCTGGGAAGATGATGTAAATCACTCATTTGCAAAACAAAACAGTGTACAAGAACAGCCTGGTA
CCGCTTGTTTATCCAAATTTTCCTCTGCAAGTGGAGCATCTGCTAGGATCAATAGCAGCAGTGTTAAGCAGGAAGCTACATTCTGTTCCC
AAAGGGATGGCGATGCCTCTTTGAATAAAGCCCTATCCTCAAGTGCTGATGATGCGTCTTTGGTTAATGCCTCAATTTCCAGCTCTGTGA
AAGCTACTTCTCCAGTGAAATCTACTACATCTATCACTGATGCTAAAAGTTGTGAGGGACAAAATCCTGAGCTACTTCCAAAAACTCCTA
TTAGTCCTCTGAAAACGGGGGTATCGAAACCAATTGTGAAGTCAACTTTATCCCAGACAGTTCCATCCAAGGGAGAATTAAGTAGAGAAA
TTTGTCTGCAATCTCAATCTAAAGACAAATCTACGACACCAGGAGGAACAGGAATTAAGCCTTTCCTGGAACGCTTTGGAGAGCGTTGTC
AAGAACATAGCAAAGAAAGTCCAGCTCGTAGCACACCCCACAGAACCCCCATTATTACTCCAAATACAAAGGCCATCCAAGAAAGATTAT
TCAAGCAAGACACATCTTCATCTACTACCCATTTAGCACAACAGCTCAAGCAGGAACGTCAAAAAGAACTAGCATGTCTTCGTGGCCGAT
TTGACAAGGGCAATATATGGAGTGCAGAAAAAGGCGGAAACTCAAAAAGCAAACAACTAGAAACCAAACAGGAAACTCACTGTCAGAGCA
CTCCCCTCAAAAAACACCAAGGTGTTTCAAAAACTCAGTCACTTCCAGTAACAGAAAAGGTGACCGAAAACCAGATACCAGCCAAAAATT
CTAGTACAGAACCTAAAGAAGTGATACGTGAAATTGAGATGAGTGTGGATGATGATGATATCAATAGTTCGAAAGTAATTAATGACCTCT
TCAGTGATGTCCTAGAGGAAGGTGAACTAGATATGGAGAAGAGCCAAGAGGAGATGGATCAAGCATTAGCAGAAAGCAGCGAAGAACAGG
AAGATGCACTGAATATCTCCTCAATGTCTTTACTTGCACCATTGGCACAAACAGTTGGTGTGGTAAGTCCAGAGTTCTGCACGGAGCTAA
ACCAGCCGACCCTGCCCAACATCCGCAAGTGGAAGGGGCCCCGGGGATGCTGGAAGGCTGTTGTTGCTGAGAAGCCCTCGAGTCAGCTCC
AGAAGGGAGCTGGGTATGCAGGATTCCTATGGGACGCGGCTGCCGGCATGGAGCTGAGAGACGCGGGTTCACAGGAGAGCTCGCCAAGCA
ACGGGCACGGGAAGCTGGCGGGCCCCAGCCCATACCTCGGGAGGTTCAAGGTGGGAAGTCACGACCTGACCCTTGTTAACCTTCACCTGG
CAGCCCTGACCCTCCTGGGGAGCGAGAATCCCAGCAAGAATCACAGTGATGGCCACCGGTTGGCGAGCTTTGCACAGACCCTACAGGAAA
CCCTGAAAGGAGAAAAGGATGTCATTATCTTAGGGGATTTTGGCCAAGGGCCAGACAGCAATGACTATGATATCCTGAGGAAAGAAAAGT
TCCACCACCTGATCCCCGCGCACACCTTCACCAACATCAGCACCAAGAACCCTCAAGGCTCGAAGTCTCTGGACAACATCTGGATCAGTA
AAAGCTTAAAGAAGGTTTTCACAGGTCACTGGGCTGTGGTGAGAGAAGGCCTCACGAACCCTTGGATTCCGGATAACTGGTCTTGGGGCG
GGGTGGCTTCTGAACACTGCCCAGTGCTAGCCGAGTTCTACACTGAAAAGGACTGGAGCAAGAAGGATGCCCCTCGGAACGGCAGCGGGG
TGGCCTTGGAGCGAAGTGAAGCCAACATCAAGCACGAGCGATGATGACACCAAATCCATGTGTCCACCCTGGGACCCAGGAGGGCACAGC
CAAGGAATGAGCCCTGTGGGGTGACGCTTCAGGGCAGAGCTGCCTTTTAATTTTTATTCTCAGAGCATCAGCACTTGAGGCCTTGCCCCA
CGCCTTCTCTGTGGACCATTCAGGACCTCCAGTGGGGGTGGCGTGCCAGGCGCGTACCCCACCAGGTGGGCAAAGCAGAAACCTGCGGGG
AGCGGAGACGCCTTTTATCTCTGGATGCCACAGACCTGAGCAGCATTGGGCTGGCTGTCCGCTGCTGACTGGATGGCAGCACAAAGACAA
TATGAGCAGAGGGAGGAGAAGAAGGGGTGCTCAGGCTGCGGGCCACAGTCCAGCAGCGCCAGAAGCACTCATTTCTGACCACCAGGCTAT
GACGTTCCTGCTGCGCATTACAGAAAGCTTTTAACTGTGATCAGGCACTCTGCTCAGATACATTGAGTGGCGATTTTTAGTTTTGTTTTG

>4833_4833_8_ANLN-EEPD1_ANLN_chr7_36459088_ENST00000396068_EEPD1_chr7_36320724_ENST00000534978_length(amino acids)=845AA_BP=586
MDPFTEKLLERTRARRENLQRKMAERPTAAPRSMTHAKRARQPLSEASNQQPLSGGEEKSCTKPSPSKKRCSDNTEVEVSNLENKQPVES
TSAKSCSPSPVSPQVQPQAADTISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLFSPMPSEEKA
ASPPRPLLSNASATPVGRRGRLANLAATICSWEDDVNHSFAKQNSVQEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLN
KALSSSADDASLVNASISSSVKATSPVKSTTSITDAKSCEGQNPELLPKTPISPLKTGVSKPIVKSTLSQTVPSKGELSREICLQSQSKD
KSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTPIITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSA
EKGGNSKSKQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKEVIREIEMSVDDDDINSSKVINDLFSDVLEEGE
LDMEKSQEEMDQALAESSEEQEDALNISSMSLLAPLAQTVGVVSPEFCTELNQPTLPNIRKWKGPRGCWKAVVAEKPSSQLQKGAGYAGF
LWDAAAGMELRDAGSQESSPSNGHGKLAGPSPYLGRFKVGSHDLTLVNLHLAALTLLGSENPSKNHSDGHRLASFAQTLQETLKGEKDVI
ILGDFGQGPDSNDYDILRKEKFHHLIPAHTFTNISTKNPQGSKSLDNIWISKSLKKVFTGHWAVVREGLTNPWIPDNWSWGGVASEHCPV

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ANLN-EEPD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with
HgeneANLNchr7:36459088chr7:36320723ENST00000265748+10241_155623.01125.0CD2AP
HgeneANLNchr7:36459088chr7:36320723ENST00000396068+9231_155586.01088.0CD2AP
HgeneANLNchr7:36459088chr7:36320724ENST00000265748+10241_155623.01125.0CD2AP
HgeneANLNchr7:36459088chr7:36320724ENST00000396068+9231_155586.01088.0CD2AP


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with
HgeneANLNchr7:36436028chr7:36336601ENST00000265748+2241_15557.3333333333333361125.0CD2AP
HgeneANLNchr7:36436028chr7:36336601ENST00000396068+2231_15557.3333333333333361088.0CD2AP
HgeneANLNchr7:36436028chr7:36336602ENST00000265748+2241_15557.3333333333333361125.0CD2AP
HgeneANLNchr7:36436028chr7:36336602ENST00000396068+2231_15557.3333333333333361088.0CD2AP
HgeneANLNchr7:36436028chr7:36336601ENST00000265748+224231_67657.3333333333333361125.0F-actin
HgeneANLNchr7:36436028chr7:36336601ENST00000396068+223231_67657.3333333333333361088.0F-actin
HgeneANLNchr7:36436028chr7:36336602ENST00000265748+224231_67657.3333333333333361125.0F-actin
HgeneANLNchr7:36436028chr7:36336602ENST00000396068+223231_67657.3333333333333361088.0F-actin
HgeneANLNchr7:36459088chr7:36320723ENST00000265748+1024231_676623.01125.0F-actin
HgeneANLNchr7:36459088chr7:36320723ENST00000396068+923231_676586.01088.0F-actin
HgeneANLNchr7:36459088chr7:36320724ENST00000265748+1024231_676623.01125.0F-actin
HgeneANLNchr7:36459088chr7:36320724ENST00000396068+923231_676586.01088.0F-actin


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANLN-EEPD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANLN-EEPD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource