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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANO2-BICD1 (FusionGDB2 ID:4869)

Fusion Gene Summary for ANO2-BICD1

check button Fusion gene summary
Fusion gene informationFusion gene name: ANO2-BICD1
Fusion gene ID: 4869
HgeneTgene
Gene symbol

ANO2

BICD1

Gene ID

57101

636

Gene nameanoctamin 2BICD cargo adaptor 1
SynonymsC12orf3|TMEM16BBICD|bic-D 1
Cytomap

12p13.31

12p11.21

Type of geneprotein-codingprotein-coding
Descriptionanoctamin-2anoctamin 2, calcium activated chloride channeltransmembrane protein 16B (eight membrane-spanning domains)protein bicaudal D homolog 1bicaudal D homolog 1cytoskeleton-like bicaudal D protein homolog 1
Modification date2020032920200313
UniProtAcc

Q9NQ90

Q96G01

Ensembl transtripts involved in fusion geneENST00000327087, ENST00000356134, 
ENST00000546188, ENST00000538154, 
ENST00000550207, ENST00000551086, 
ENST00000551848, ENST00000281474, 
ENST00000548411, 
Fusion gene scores* DoF score8 X 9 X 6=43213 X 12 X 6=936
# samples 914
** MAII scorelog2(9/432*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/936*10)=-2.74108170263844
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANO2 [Title/Abstract] AND BICD1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANO2(6030206)-BICD1(32446928), # samples:2
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
TgeneBICD1

GO:0033365

protein localization to organelle

12447383|20089649


check buttonFusion gene breakpoints across ANO2 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BICD1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4BLCATCGA-FD-A6TC-01AANO2chr12

6030206

-BICD1chr12

32446928

+


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Fusion Gene ORF analysis for ANO2-BICD1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-intronENST00000327087ENST00000550207ANO2chr12

6030206

-BICD1chr12

32446928

+
5CDS-intronENST00000327087ENST00000551086ANO2chr12

6030206

-BICD1chr12

32446928

+
5CDS-intronENST00000327087ENST00000551848ANO2chr12

6030206

-BICD1chr12

32446928

+
5CDS-intronENST00000356134ENST00000550207ANO2chr12

6030206

-BICD1chr12

32446928

+
5CDS-intronENST00000356134ENST00000551086ANO2chr12

6030206

-BICD1chr12

32446928

+
5CDS-intronENST00000356134ENST00000551848ANO2chr12

6030206

-BICD1chr12

32446928

+
5CDS-intronENST00000546188ENST00000550207ANO2chr12

6030206

-BICD1chr12

32446928

+
5CDS-intronENST00000546188ENST00000551086ANO2chr12

6030206

-BICD1chr12

32446928

+
5CDS-intronENST00000546188ENST00000551848ANO2chr12

6030206

-BICD1chr12

32446928

+
In-frameENST00000327087ENST00000281474ANO2chr12

6030206

-BICD1chr12

32446928

+
In-frameENST00000327087ENST00000548411ANO2chr12

6030206

-BICD1chr12

32446928

+
In-frameENST00000356134ENST00000281474ANO2chr12

6030206

-BICD1chr12

32446928

+
In-frameENST00000356134ENST00000548411ANO2chr12

6030206

-BICD1chr12

32446928

+
In-frameENST00000546188ENST00000281474ANO2chr12

6030206

-BICD1chr12

32446928

+
In-frameENST00000546188ENST00000548411ANO2chr12

6030206

-BICD1chr12

32446928

+
intron-3CDSENST00000538154ENST00000281474ANO2chr12

6030206

-BICD1chr12

32446928

+
intron-3CDSENST00000538154ENST00000548411ANO2chr12

6030206

-BICD1chr12

32446928

+
intron-intronENST00000538154ENST00000550207ANO2chr12

6030206

-BICD1chr12

32446928

+
intron-intronENST00000538154ENST00000551086ANO2chr12

6030206

-BICD1chr12

32446928

+
intron-intronENST00000538154ENST00000551848ANO2chr12

6030206

-BICD1chr12

32446928

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000327087ANO2chr126030206-ENST00000548411BICD1chr1232446928+8798594722675867
ENST00000327087ANO2chr126030206-ENST00000281474BICD1chr1232446928+33465947230951007
ENST00000546188ANO2chr126030206-ENST00000548411BICD1chr1232446928+8798594722675867
ENST00000546188ANO2chr126030206-ENST00000281474BICD1chr1232446928+33465947230951007
ENST00000356134ANO2chr126030206-ENST00000548411BICD1chr1232446928+8798594722675867
ENST00000356134ANO2chr126030206-ENST00000281474BICD1chr1232446928+33465947230951007

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000327087ENST00000548411ANO2chr126030206-BICD1chr1232446928+0.0001925180.99980754
ENST00000327087ENST00000281474ANO2chr126030206-BICD1chr1232446928+0.0031847580.99681526
ENST00000546188ENST00000548411ANO2chr126030206-BICD1chr1232446928+0.0001925180.99980754
ENST00000546188ENST00000281474ANO2chr126030206-BICD1chr1232446928+0.0031847580.99681526
ENST00000356134ENST00000548411ANO2chr126030206-BICD1chr1232446928+0.0001925180.99980754
ENST00000356134ENST00000281474ANO2chr126030206-BICD1chr1232446928+0.0031847580.99681526

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Fusion Genomic Features for ANO2-BICD1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANO2chr126030205-BICD1chr1232446927+1.61E-121
ANO2chr126030205-BICD1chr1232446927+1.61E-121

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANO2-BICD1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:6030206/chr12:32446928)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANO2

Q9NQ90

BICD1

Q96G01

FUNCTION: Calcium-activated chloride channel (CaCC) which may play a role in olfactory signal transduction. Odorant molecules bind to odor-sensing receptors (OSRs), leading to an increase in calcium entry that activates CaCC current which amplifies the depolarization of the OSR cells, ANO2 seems to be the underlying chloride channel involved in this process. May mediate light perception amplification in retina. {ECO:0000269|PubMed:19474308, ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:21890523, ECO:0000269|PubMed:21984732}.FUNCTION: Regulates coat complex coatomer protein I (COPI)-independent Golgi-endoplasmic reticulum transport by recruiting the dynein-dynactin motor complex.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgeneBICD1chr12:6030206chr12:32446928ENST00000281474110319_496142976.0Coiled coilOntology_term=ECO:0000255
TgeneBICD1chr12:6030206chr12:32446928ENST00000281474110663_803142976.0Coiled coilOntology_term=ECO:0000255
TgeneBICD1chr12:6030206chr12:32446928ENST0000054841119319_4961422736.0Coiled coilOntology_term=ECO:0000255
TgeneBICD1chr12:6030206chr12:32446928ENST0000054841119663_8031422736.0Coiled coilOntology_term=ECO:0000255
TgeneBICD1chr12:6030206chr12:32446928ENST00000551848011_265094.0Coiled coilOntology_term=ECO:0000255
TgeneBICD1chr12:6030206chr12:32446928ENST0000055184801319_496094.0Coiled coilOntology_term=ECO:0000255
TgeneBICD1chr12:6030206chr12:32446928ENST0000055184801663_803094.0Coiled coilOntology_term=ECO:0000255

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-3261001_1003174999.0MotifNote=DLG4 binding (PDZ)
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-3271001_10031741000.0MotifNote=DLG4 binding (PDZ)
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-3261_365174999.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326387_434174999.0Topological domainExtracellular
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326456_538174999.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326560_582174999.0Topological domainExtracellular
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326604_623174999.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326645_748174999.0Topological domainExtracellular
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326770_801174999.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326823_907174999.0Topological domainExtracellular
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326929_1003174999.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-3271_3651741000.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327387_4341741000.0Topological domainExtracellular
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327456_5381741000.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327560_5821741000.0Topological domainExtracellular
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327604_6231741000.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327645_7481741000.0Topological domainExtracellular
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327770_8011741000.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327823_9071741000.0Topological domainExtracellular
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327929_10031741000.0Topological domainCytoplasmic
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326366_386174999.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326435_455174999.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326539_559174999.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326583_603174999.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326624_644174999.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326749_769174999.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326802_822174999.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000327087-326908_928174999.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327366_3861741000.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327435_4551741000.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327539_5591741000.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327583_6031741000.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327624_6441741000.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327749_7691741000.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327802_8221741000.0TransmembraneHelical
HgeneANO2chr12:6030206chr12:32446928ENST00000356134-327908_9281741000.0TransmembraneHelical
TgeneBICD1chr12:6030206chr12:32446928ENST000002814741101_265142976.0Coiled coilOntology_term=ECO:0000255
TgeneBICD1chr12:6030206chr12:32446928ENST00000548411191_2651422736.0Coiled coilOntology_term=ECO:0000255


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Fusion Gene Sequence for ANO2-BICD1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4869_4869_1_ANO2-BICD1_ANO2_chr12_6030206_ENST00000327087_BICD1_chr12_32446928_ENST00000281474_length(transcript)=3346nt_BP=594nt
CCAGGCTCCTTCTCTATAAAGTGGGATCTATCATGACCAGCCTACCTTATCAATATAGGAGAGAAAATCTTCATGCCTGAAGATATACCC
CTGCTCCCTGGCTCCCCACGCCGGCTGAGCCCTCAGGCAGGGTCCAGAGGGGGCCAGGGCCCCAAACATGGACAGCAGTGTCTCAAGATG
CCAGGTCCCCGGGCCCCAGGTCTGCAGGGCGGTTCCAACAGAGATCCTGGCCAGCCCTGCGGTGGAGAGAGCACCCGCAGCAGCTCTGTC
ATCAACAACTATCTGGATGCCAATGAGCCTGTGTCCTTGGAGGCCCGTCTTAGCCGCATGCACTTCCATGACAGTCAGAGGAAGGTCGAC
TATGTACTTGCCTACCACTACCGGAAACGCGGGGTGCACCTGGCCCAAGGCTTCCCTGGCCACTCGCTGGCTATCGTCTCCAATGGGGAG
ACAGGCAAGGAGCCTCATGCTGGGGGCCCAGGTGACATTGAGCTGGGACCGCTCGATGCCCTGGAGGAGGAGAGGAAGGAGCAGCGGGAG
GAATTTGAGCACAATCTGATGGAGGCTGGACTGGAGCTTGAGAAGGACTTGGAGAACAATGAGATGGTGGAGCTACAGAGAATACGGATG
AAGGATGAAATCCGAGAATATAAGTTCCGGGAGGCACGGCTCCTTCAGGACTATACTGAATTGGAAGAAGAAAATATCACATTGCAGAAA
CTAGTGTCCACGTTGAAGCAGAACCAGGTTGAATACGAAGGCTTAAAGCATGAGATTAAGCGATTTGAGGAGGAGACGGTACTGCTGAAC
AGCCAGCTGGAAGATGCCATCCGATTGAAAGAGATTGCTGAGCACCAACTGGAAGAAGCCCTCGAGACTTTAAAAAATGAAAGAGAGCAA
AAGAACAACCTGCGGAAGGAGCTCTCCCAGTATATCAGCCTCAATGATAACCATATCAGCATCTCAGTAGATGGACTCAAATTTGCCGAG
GATGGGAGTGAACCAAACAATGATGACAAAATGAACGGTCATATCCATGGGCCTCTTGTGAAACTGAATGGAGACTATCGGACTCCCACC
TTAAGGAAAGGAGAGTCTCTGAACCCTGTCTCTGACTTATTCAGTGAGCTGAACATTTCAGAAATACAGAAGTTGAAGCAGCAGCTTATG
CAGGTAGAGCGGGAAAAGGCCATTCTTTTGGCCAACCTACAGGAGTCACAGACACAGCTGGAACACACCAAGGGGGCACTGACGGAGCAG
CATGAGCGGGTGCACCGGCTCACAGAGCACGTCAATGCCATGAGGGGCCTGCAAAGCAGCAAGGAGCTCAAGGCTGAGCTGGACGGGGAG
AAGGGCCGGGACTCAGGGGAGGAGGCCCATGACTATGAGGTGGACATCAATGGTTTAGAGATCCTTGAATGCAAATACAGGGTGGCAGTA
ACTGAGGTGATTGATCTGAAAGCTGAAATTAAGGCCTTAAAGGAGAAATATAATAAATCTGTAGAAAACTACACTGATGAGAAGGCCAAG
TATGAGAGTAAAATCCAGATGTATGATGAGCAGGTGACAAGCCTTGAGAAGACCACCAAGGAGAGTGGTGAGAAGATGGCCCACATGGAG
AAGGAGTTGCAAAAGATGACCAGCATAGCCAACGAAAATCACAGTACCCTTAATACGGCCCAGGATGAGTTAGTGACATTCAGTGAGGAG
TTAGCTCAGCTTTACCACCATGTGTGTCTATGTAATAATGAAACTCCCAACAGGGTCATGCTGGATTACTATAGGCAGAGCAGAGTCACC
CGCAGTGGCAGCCTGAAAGGGCCCGATGATCCCAGAGGACTTTTGTCCCCACGATTAGCCAGGCGGGGTGTGTCATCCCCGGTAGAAACA
AGGACCTCATCTGAACCAGTTGCAAAAGAAAGCACAGAGGCCAGCAAAGAACCAAGTCCAACTAAGACCCCCACAATCTCTCCTGTTATT
ACTGCCCCACCGTCATCTCCAGTATTGGATACAAGTGACATCCGCAAAGAGCCAATGAATATCTACAACCTTAATGCCATAATCCGGGAC
CAAATCAAGCATCTGCAGAAAGCTGTGGACCGGTCCTTGCAACTGTCTCGTCAAAGAGCAGCGGCTCGGGAGCTAGCCCCCATGATTGAT
AAAGACAAGGAAGCCTTAATGGAAGAGATCCTCAAGCTAAAGTCCCTGCTGAGCACCAAACGGGAGCAGATCGCCACATTGAGGGCGGTG
TTGAAAGCCAACAAGCAGACAGCTGAGGTGGCGCTAGCTAATCTCAAGAACAAATATGAAAATGAAAAAGCAATGGTGACTGAAACCATG
ACGAAGCTTAGAAATGAACTGAAGGCTTTGAAAGAAGATGCTGCAACCTTCTCATCCCTGAGAGCAATGTTTGCAACAAGATGTGATGAA
TATGTCACCCAGTTGGATGAGATGCAGAGACAGTTAGCAGCTGCAGAGGATGAGAAGAAGACTCTGAACACTTTGTTACGAATGGCTATC
CAGCAAAAACTCGCCCTGACCCAGAGGCTGGAGGACTTAGAGTTTGACCATGAGCAGTCCCGACGCAGCAAAGGCAAACTTGGAAAGAGC
AAGATCGGCAGCCCTAAAGTAAGTGGGGAGGCATCAGTCACCGTGCCCACCATAGACACTTACCTCCTGCATAGTCAGGGCCCACAGACA
CCCAACATTCGGGTCAGCAGTGGCACTCAGAGGAAAAGACAATTTTCACCTTCCCTTTGTGATCAGAGCCGTCCCAGGACTTCAGGGGCT
TCCTACCTACAGAATTTATTAAGAGTTCCCCCTGATCCCACCTCCACAGAATCATTTCTTCTGAAGGGCCCCCCTTCCATGAGTGAATTC
ATCCAAGGGCACCGGCTCAGCAAGGAAAAAAGGTTAACCGTGGCTCCACCAGATTGTCAGCAGCCTGCTGCCTCCGTACCGCCACAGTGC
TCACAACTAGCCGGGAGGCAAGACTGCCCAACTGTCAGTCCTGACACAGCTCTCCCTGAGGAGCAGCCACATTCCAGCTCCCAGTGCGCC
CCTCTCCACTGTCTCTCCAAGCCTCCTCACCCCTAGTCTTCATCTCCTGTGGACGAACATCTGGGGTGGAAGTTTTGTAGCCACACACAG
GATACTGCCCAAGATCCAGCGGGTGTTTTCTTCTCGGTTGTTAGATGTACAATTGGATTAATGTCCATCGTTTTGGAAGACGAGAGAAAG
TTGAGAAGAACACGAAGCACAGACCCTGATGTGATAAAACATTTTGTGGTTTCTCTGAGTCACAGATAAACTTCTGCCATCAAATGGCTA

>4869_4869_1_ANO2-BICD1_ANO2_chr12_6030206_ENST00000327087_BICD1_chr12_32446928_ENST00000281474_length(amino acids)=1007AA_BP=174
MPEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGESTRSSSVINNYLDANEPVSLEARLSRMHFHD
SQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENNEMVE
LQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETL
KNEREQKNNLRKELSQYISLNDNHISISVDGLKFAEDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLRKGESLNPVSDLFSELNISEIQK
LKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKAELDGEKGRDSGEEAHDYEVDINGLEILEC
KYRVAVTEVIDLKAEIKALKEKYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQDEL
VTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVETRTSSEPVAKESTEASKEPSPTKTP
TISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQI
ATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNT
LLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSGEASVTVPTIDTYLLHSQGPQTPNIRVSSGTQRKRQFSPSLCDQSR
PRTSGASYLQNLLRVPPDPTSTESFLLKGPPSMSEFIQGHRLSKEKRLTVAPPDCQQPAASVPPQCSQLAGRQDCPTVSPDTALPEEQPH

--------------------------------------------------------------
>4869_4869_2_ANO2-BICD1_ANO2_chr12_6030206_ENST00000327087_BICD1_chr12_32446928_ENST00000548411_length(transcript)=8798nt_BP=594nt
CCAGGCTCCTTCTCTATAAAGTGGGATCTATCATGACCAGCCTACCTTATCAATATAGGAGAGAAAATCTTCATGCCTGAAGATATACCC
CTGCTCCCTGGCTCCCCACGCCGGCTGAGCCCTCAGGCAGGGTCCAGAGGGGGCCAGGGCCCCAAACATGGACAGCAGTGTCTCAAGATG
CCAGGTCCCCGGGCCCCAGGTCTGCAGGGCGGTTCCAACAGAGATCCTGGCCAGCCCTGCGGTGGAGAGAGCACCCGCAGCAGCTCTGTC
ATCAACAACTATCTGGATGCCAATGAGCCTGTGTCCTTGGAGGCCCGTCTTAGCCGCATGCACTTCCATGACAGTCAGAGGAAGGTCGAC
TATGTACTTGCCTACCACTACCGGAAACGCGGGGTGCACCTGGCCCAAGGCTTCCCTGGCCACTCGCTGGCTATCGTCTCCAATGGGGAG
ACAGGCAAGGAGCCTCATGCTGGGGGCCCAGGTGACATTGAGCTGGGACCGCTCGATGCCCTGGAGGAGGAGAGGAAGGAGCAGCGGGAG
GAATTTGAGCACAATCTGATGGAGGCTGGACTGGAGCTTGAGAAGGACTTGGAGAACAATGAGATGGTGGAGCTACAGAGAATACGGATG
AAGGATGAAATCCGAGAATATAAGTTCCGGGAGGCACGGCTCCTTCAGGACTATACTGAATTGGAAGAAGAAAATATCACATTGCAGAAA
CTAGTGTCCACGTTGAAGCAGAACCAGGTTGAATACGAAGGCTTAAAGCATGAGATTAAGCGATTTGAGGAGGAGACGGTACTGCTGAAC
AGCCAGCTGGAAGATGCCATCCGATTGAAAGAGATTGCTGAGCACCAACTGGAAGAAGCCCTCGAGACTTTAAAAAATGAAAGAGAGCAA
AAGAACAACCTGCGGAAGGAGCTCTCCCAGTATATCAGCCTCAATGATAACCATATCAGCATCTCAGTAGATGGACTCAAATTTGCCGAG
GATGGGAGTGAACCAAACAATGATGACAAAATGAACGGTCATATCCATGGGCCTCTTGTGAAACTGAATGGAGACTATCGGACTCCCACC
TTAAGGAAAGGAGAGTCTCTGAACCCTGTCTCTGACTTATTCAGTGAGCTGAACATTTCAGAAATACAGAAGTTGAAGCAGCAGCTTATG
CAGGTAGAGCGGGAAAAGGCCATTCTTTTGGCCAACCTACAGGAGTCACAGACACAGCTGGAACACACCAAGGGGGCACTGACGGAGCAG
CATGAGCGGGTGCACCGGCTCACAGAGCACGTCAATGCCATGAGGGGCCTGCAAAGCAGCAAGGAGCTCAAGGCTGAGCTGGACGGGGAG
AAGGGCCGGGACTCAGGGGAGGAGGCCCATGACTATGAGGTGGACATCAATGGTTTAGAGATCCTTGAATGCAAATACAGGGTGGCAGTA
ACTGAGGTGATTGATCTGAAAGCTGAAATTAAGGCCTTAAAGGAGAAATATAATAAATCTGTAGAAAACTACACTGATGAGAAGGCCAAG
TATGAGAGTAAAATCCAGATGTATGATGAGCAGGTGACAAGCCTTGAGAAGACCACCAAGGAGAGTGGTGAGAAGATGGCCCACATGGAG
AAGGAGTTGCAAAAGATGACCAGCATAGCCAACGAAAATCACAGTACCCTTAATACGGCCCAGGATGAGTTAGTGACATTCAGTGAGGAG
TTAGCTCAGCTTTACCACCATGTGTGTCTATGTAATAATGAAACTCCCAACAGGGTCATGCTGGATTACTATAGGCAGAGCAGAGTCACC
CGCAGTGGCAGCCTGAAAGGGCCCGATGATCCCAGAGGACTTTTGTCCCCACGATTAGCCAGGCGGGGTGTGTCATCCCCGGTAGAAACA
AGGACCTCATCTGAACCAGTTGCAAAAGAAAGCACAGAGGCCAGCAAAGAACCAAGTCCAACTAAGACCCCCACAATCTCTCCTGTTATT
ACTGCCCCACCGTCATCTCCAGTATTGGATACAAGTGACATCCGCAAAGAGCCAATGAATATCTACAACCTTAATGCCATAATCCGGGAC
CAAATCAAGCATCTGCAGAAAGCTGTGGACCGGTCCTTGCAACTGTCTCGTCAAAGAGCAGCGGCTCGGGAGCTAGCCCCCATGATTGAT
AAAGACAAGGAAGCCTTAATGGAAGAGATCCTCAAGCTAAAGTCCCTGCTGAGCACCAAACGGGAGCAGATCGCCACATTGAGGGCGGTG
TTGAAAGCCAACAAGCAGACAGCTGAGGTGGCGCTAGCTAATCTCAAGAACAAATATGAAAATGAAAAAGCAATGGTGACTGAAACCATG
ACGAAGCTTAGAAATGAACTGAAGGCTTTGAAAGAAGATGCTGCAACCTTCTCATCCCTGAGAGCAATGTTTGCAACAAGATGTGATGAA
TATGTCACCCAGTTGGATGAGATGCAGAGACAGTTAGCAGCTGCAGAGGATGAGAAGAAGACTCTGAACACTTTGTTACGAATGGCTATC
CAGCAAAAACTCGCCCTGACCCAGAGGCTGGAGGACTTAGAGTTTGACCATGAGCAGTCCCGACGCAGCAAAGGCAAACTTGGAAAGAGC
AAGATCGGCAGCCCTAAAATTGTCAGCAGCCTGCTGCCTCCGTACCGCCACAGTGCTCACAACTAGCCGGGAGGCAAGACTGCCCAACTG
TCAGTCCTGACACAGCTCTCCCTGAGGAGCAGCCACATTCCAGCTCCCAGTGCGCCCCTCTCCACTGTCTCTCCAAGCCTCCTCACCCCT
AGTCTTCATCTCCTGTGGACGAACATCTGGGGTGGAAGTTTTGTAGCCACACACAGGATACTGCCCAAGATCCAGCGGGTGTTTTCTTCT
CGGTTGTTAGATGTACAATTGGATTAATGTCCATCGTTTTGGAAGACGAGAGAAAGTTGAGAAGAACACGAAGCACAGACCCTGATGTGA
TAAAACATTTTGTGGTTTCTCTGAGTCACAGATAAACTTCTGCCATCAAATGGCTACAGTTCATTTAAATTTAAAAAAAAGAAAAAAGAA
ACAGAAAACGTGTCTCAGATGGCTGGCTTTACCTCGATAGCATAAGAGAGACCTAAGACATGTAAAATACGTATATTGCAGTATCATCTT
TCCTCACACTCCAAATTCAGCTAGGGAAGTTGATTCCAATATGTTTGTCATTGATATTTATTTTGTACTTTATTTGCTACATGATTTATG
TCTATACAAATAATTTCTCTGAGGTGAATTTAATTCATTTATTTTCAAATAAGCATAATTTGCTCAATTAAGTATGAGTTTGAATTTAGT
TTGAAATCTGGAATTGGCCAGACTGTGGTCATTTTTCTTGCACAAAATGATAAATGAGGTGCATCAGAATGTTAACAATAACTGTATTTT
GCTGCTACGCTGGTATTGTTTAGGCACTTACTTTCTAATCAGTAGCTCATTAACTGCTGGGTTTTGTTTTTGTATTTTTAACTAGAGTTC
TTCACTGGACATTACTAAGTAAATCTAAGAAAGAGACTAAGTTATGATTTATTGACTTATTCAAGTTTTGATGGCATCTTTACTTTTATT
TTTTCATTGCAGTTGAGTAGATGTACTGGTGCTGCTCCTTTGTATGTGTGTATGTGTGTGATAACGTTAAAGAAGGCTCAATAACTTGAA
GGGAAAAAAATGGTGTGTTTATTTAATGACCAGAATTTTTTTTACTTCTCCCAAAATCAGGGTCCTACTGAGTCTTTCCTGATAAAAGGT
ATCAAGTACAAATGGGAAAATATATACATATATAGATGTAAGATAGCCTTTAATTAATTAATTTACCCAGAGAGTGTTCAAAGTTTGATT
AAAATTGTATGTTTTGTTGTTGTTAGTTTTTTTCATAACGAATCTTCCTTGCCAAAAAAACAATAGATAATAAACCTTAGCTCATTGTCT
ACTTTTGACAAACACTCAGGTGCCTACAAACATTCTATTATCTTGAGATAATACATGTTCCTGGTTAATTTACAGATTCTGCTGGGTAAC
TTTTATGACTTGATTTAAGGCAGTGGATTTTCATAGCAAAATTTATTTTGCACATAATCTGACAAACAAGGAAAACAGCTAACTGAGCTG
AAAGGTCTAACACTCTCGGGCTCCTTAACCATCAAGTGCTGCCCACACAATTGCTCCTAGCCCTGATTCCTTGTCTTTGTCAGGTAGCCT
TAACTTATTTAAAACCATAAGGGTTTGACCTTTTCATATAAAGACATCTGTAACTTCTCTTCAAAACAAAAATGACCCTCACTGTTAACA
CAAAGGACAGTTACCAGTGTAGGGCACTGAGAAAGGAGATCCAGGAGCCACTCAGCTTATTGAGCGGACATGGGTGGCACAGAAATGGAG
TGGTCCATCAGAGACCAAATGGTAAGTCGTAAAGCACATTGCAGGAGCTTTCGTTAGTCATACGCCTATTAAGTAGTGGTCGCTATTACC
AAAGCAACCAGGACGTTTTGTGTTCTTTATATGAGTGCTATTTTCCACAGTGTCATTTATTATGCAACGTGGAGTAAAGAGTTGAAATCT
TCACCAAAATAAGGGTTCAGGTTAAAGTACAGAAACAGAAACAAAACGATTCGACATGAAGTTCCCAACCATAGCAGCCTAACCTTCTGC
TCTTTTCTACCTGCATGGCCTTGCTGTTCCTAAACATTGTCTTCATTTCACTGGCGTTGTATCTGCCTAGTACCAGTATTAGTGAGACTG
TGGATTTTATCAGAGTTCAATGAAAGAAAGCTTACCCCTGCCCTCACTTTGTGTTTTTTATTTTTCCCCCTTTCTCAAGCACCACGTATT
TGGACCTGAGAAGTGGCATAGCTGCTAAGTTGACTTTTAATAAAAAACTGTTTGTGCCTGAGGGAAATATATGCCTTTTTAAAAAGTACC
TCAGAACATGTTCGTAGATCGTCTCATCGGTTTTGTTTGGTGGGACTGGGAGTTCAGCAGGAAGTATTGTCTGTGTGTGATGACGGGGCA
GTATTGCCAGTCGGCAATGTTGTATTTGCATTCTTTATCCCTAACTCTGAATCTAGGACTCCATGAAAAGCCGGGTCACCCACAAAACAT
TTCTTCCAATACAAAGTGTATTATTACGTCTATTATAAACTAGTTTCATTTCAGTTATTTATCTTCATAGAGTGGGAAAGTCTTTTTCTG
AAATACTAATTCTATGAAAATAATAATTTTAGTGAATCTTTGCCAAGAAGTTATAGAAACTTGGAAATAAATTTCTCATTTTCAGCACAA
AATTAAGTGATAGTCCCTAAGCAGTAAGAGAGAATACCATGTATTTACACTGTGGCATCATTTAGTATAGTTTACACTGAGCCATATTTA
TTTATAGGCATTTAAAGTGAATCAGTATGTGTAGTGTTGATAAAAATCAGTATCTGTAAAGATAACATCAGGAATTCAAAAGGAAATTGA
AAAGGGGCAGAACTAGTGAGAACCAAAAAGAATGAACTCCAGTAAGACTAATTGAAGACATACTTGGAGAGGAAAAATAAACAGCAGAAA
TGCACTAAAAAATACTGGCTAATTATTGCAAACAGAGTGAGCAAAGATTAATGCTAACTAGTAAAAGTAGTTAGCAAAGTAAACAGGTAG
TTTTTTAAAAGTAAGCACAATTACAATATTGAATAGTATGGAGAAATGCTTTTCTCCTGAGGATTTTCCTTAATCAAAAAATAAGAAGAA
GCAATAAATTGTCTTTGGCCTGAGTGCTGAGTGGCATAAATAAAGGAGCTTGGCTTAATCTTTCTGGTCCACACATAATCCATTAGATCC
CATTCATATATCCAACTCTGGATTCTAATAAAATAATTTGGAGAACTTTGAGAAAAAGGAAAACTGTTAAATAAGAAAAGACCTATTTAG
AAATTATACTTTAGTCTAACGAAGAGGAGGTACAATAGTAGTCTTCAAGAAAAGAATATTTAACAAATGATAGATATCAGCTATAGATAT
TGTTACTAAGTCTAGAATAAAAAAGGCTTCAGTGTGAAGGATGTATAGTAACTCTAGGAAAGAGATTTTTAACACTGGGAAATTAACGTG
GAAATTGATAATCATAAAGAATATTTGTTTTGTAAAAATTGAATATCATTGGTGGTCTAGTAAGTATTAAGTGGCAAGATAGGAGAATGC
ATTTCAGTTCTGGGAGCTCATAATCCTGTGATTCTTTTATTTTAAGTTTTAAAATACATTAAAATTTTACTGGTTAATCATAAAATATTT
TATATTTGAAAATAGGATGGCAATCTTTATTTTTCCAAGATATTTGTTGGAAAAAAATGATCGTTGGTATTATTTTTTCTTTCAGCTATA
TTCCATGGTATCTTTAAAATTGTTCAGAATATAGGACTTTTACTAAAAAAATTCAATTGTCAGAGTCTAAAAAAACAATGTCCTCAGGAA
TACTTCAGAAATAGAAGGTATGCAATCCCTTAGTGGGGGGCAAACACATTTCAGATTTCGTCTTTATTTAAAAGGATCTTCAGTCTACAA
CATTTGCTTTTTTCGTGCTTTGGAAAATATCCTTGTGCAGATAAGTTCTTCTGTTTGAAACAAGCATGAAACATTGGTCCAATAACCTAA
GAATGTGGAGATTTCTTGATATTCTGTATTAATTAAAGTTCTCTACATGTCTCAAATGGAGATCACAAAACATGAAAAGGAAGAAATGAA
ATATCTTTTCTTCTGGGATGAGTGTCAATTTTAATGTATAATTGTCATAATCAATCAGCCAAAAGTTACAATCTGTCCCTCAGAGACATT
GGGGGAAGCTGATGGATTTCCAGTAAGGAACTGTGGTGGGTTCAAACTCAGGCTGCCACAAATACATTGATATGGTAGGTAGGAAGTAGG
ACTAAATTTGAAAGAAACTTATGGGATAAAGTTCACAATTTTAAAAAGGTTGCCCTCCAGTTTTTTTGTTTGTTTATAAACTAGAGTGAT
TTTTAAGTAACCCTTATATTTAAGGCTGCAAAAAATGTACAAGAGTATGTTTTCAAGTAAAGGGAACATAATTCTTCAAAAAGCTGTTGA
ACTGGAGTTATGATAGGTTATGACAGAGAGCATGATCAGTGCTGATACTGACAAGTACTTTTTTACCTTAAAATCAACTTCTATGGAACT
ACAAGATCAATCTAGCTCCCGAGTGACATTTTCCATTGTCTGTAATAATGCCCTCGGATGAGTTGTGTCTAAAATTAAGTTCATCTTTAT
TTATATGCGAACTTAACTGCCATAGTCCCTAATGTATTGCGTTTGTAACCTGATCGTATTATGTTTACAGCTGAAAGATTTCATCTAGAC
ATGTCTTTCGTCCTTATTATTCAAAGTGTAATTGAAAGAGATATTTAGTATTAAGACATGTTCCCCAATTGAGAATTTTCCAGAATATTC
TACTTAAGAAGAAGAAGAGCAATTAACTGCCTTTAGTGTAAGGGCGAGAGTGCATAGAAATATGCAATGTAAAATGTTTGCATGAATTAT
TTCACATCATGTAAGCTTTCCCATATTCATAAGATGAACACTATAGAAGTCTCATTTCTCTGTGATCTTCTGTCCATTAGGAAAGTAAGG
AGATTGTTATCTATATCTAGTCTCCTTTCCATATTGAACTGCATGGCTCTAATCCTCAGTGTATTTTTATCCCTTCTCGAGTTATTTAAA
ATTTGCCCTATTTAAGCTGAAGCCTGGATAAACTGCTGAGCCAGATTATTCCTGTGATTGGAGTTTAATTGCTGTAGAACACTTGTTGAG
AACACATTTTTTACTTTTTTTCTTTCAGAATTATTCCTCAATCATTGTTCTCTAATGAAAACACCGAGAAGTAAATCTGGTGCTTCTTAG
TGTAAATATGTTTTTCTTTTTAAAAAGTCATTTTAAAACAAAGATGAGAGAACTATAAAGTAAGGGGAAATATCATTTTATTTAAAAATA
ATTATTCAATGATAGATAATGGAGATACAGAATGACTCATTGGGTTCATAGGTATGATTTGTGCAGCCAGTCTTAGAGGAAATACATCAT
TTTAACATTATTCCCACAAAATGTTAAAGCTCAATGGTTTGACTATGAGAGTCAAACAATTACTATTTGAAAATCTCTTATGACATTTTT
ATAATCTACTCTGTTTTTATTTGCATGATTATGCTTATGTGATGAACCATCCATGATTCTGATATTGTATTTCTTTCCAGTATTAACATG
TGTATTGTGTGGCCAACTCTGATTTGTACACCGTATTATTGTTGTAATGATTCAACTGTTCCTACATTTAATTGCAGTTTAATTATTATG
CCTTTTGGGGTTAAATGATGTGAAGTGTTTCCACCTACTGATAAATACCATATGAAAACACGACTAAAAGACTGATTTAAGAAACTTGTT
ATTTTTAAAAATATGAATTTCAAAAGAAATGTTCTCAAAGACACATGCATTTATTTTAAATTCAAAAAATTCTTATGAATTTATTATTGC
TTGTACTTTAACTTTTTTTATTGTAGACAATCCTAAGTGAATAATGTCTCATGGGAGAACACATGATATGTGCTTGTATTTGTGTAATCT
GATCATGCACTCAATGGTTGGAAAAGGCACTCCAGTGCTAAGAAAATAACCAGAAGCCAATATATCGATTCTTATATCTCGGTTTATGTT

>4869_4869_2_ANO2-BICD1_ANO2_chr12_6030206_ENST00000327087_BICD1_chr12_32446928_ENST00000548411_length(amino acids)=867AA_BP=174
MPEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGESTRSSSVINNYLDANEPVSLEARLSRMHFHD
SQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENNEMVE
LQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETL
KNEREQKNNLRKELSQYISLNDNHISISVDGLKFAEDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLRKGESLNPVSDLFSELNISEIQK
LKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKAELDGEKGRDSGEEAHDYEVDINGLEILEC
KYRVAVTEVIDLKAEIKALKEKYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQDEL
VTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVETRTSSEPVAKESTEASKEPSPTKTP
TISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQI
ATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNT

--------------------------------------------------------------
>4869_4869_3_ANO2-BICD1_ANO2_chr12_6030206_ENST00000356134_BICD1_chr12_32446928_ENST00000281474_length(transcript)=3346nt_BP=594nt
CCAGGCTCCTTCTCTATAAAGTGGGATCTATCATGACCAGCCTACCTTATCAATATAGGAGAGAAAATCTTCATGCCTGAAGATATACCC
CTGCTCCCTGGCTCCCCACGCCGGCTGAGCCCTCAGGCAGGGTCCAGAGGGGGCCAGGGCCCCAAACATGGACAGCAGTGTCTCAAGATG
CCAGGTCCCCGGGCCCCAGGTCTGCAGGGCGGTTCCAACAGAGATCCTGGCCAGCCCTGCGGTGGAGAGAGCACCCGCAGCAGCTCTGTC
ATCAACAACTATCTGGATGCCAATGAGCCTGTGTCCTTGGAGGCCCGTCTTAGCCGCATGCACTTCCATGACAGTCAGAGGAAGGTCGAC
TATGTACTTGCCTACCACTACCGGAAACGCGGGGTGCACCTGGCCCAAGGCTTCCCTGGCCACTCGCTGGCTATCGTCTCCAATGGGGAG
ACAGGCAAGGAGCCTCATGCTGGGGGCCCAGGTGACATTGAGCTGGGACCGCTCGATGCCCTGGAGGAGGAGAGGAAGGAGCAGCGGGAG
GAATTTGAGCACAATCTGATGGAGGCTGGACTGGAGCTTGAGAAGGACTTGGAGAACAATGAGATGGTGGAGCTACAGAGAATACGGATG
AAGGATGAAATCCGAGAATATAAGTTCCGGGAGGCACGGCTCCTTCAGGACTATACTGAATTGGAAGAAGAAAATATCACATTGCAGAAA
CTAGTGTCCACGTTGAAGCAGAACCAGGTTGAATACGAAGGCTTAAAGCATGAGATTAAGCGATTTGAGGAGGAGACGGTACTGCTGAAC
AGCCAGCTGGAAGATGCCATCCGATTGAAAGAGATTGCTGAGCACCAACTGGAAGAAGCCCTCGAGACTTTAAAAAATGAAAGAGAGCAA
AAGAACAACCTGCGGAAGGAGCTCTCCCAGTATATCAGCCTCAATGATAACCATATCAGCATCTCAGTAGATGGACTCAAATTTGCCGAG
GATGGGAGTGAACCAAACAATGATGACAAAATGAACGGTCATATCCATGGGCCTCTTGTGAAACTGAATGGAGACTATCGGACTCCCACC
TTAAGGAAAGGAGAGTCTCTGAACCCTGTCTCTGACTTATTCAGTGAGCTGAACATTTCAGAAATACAGAAGTTGAAGCAGCAGCTTATG
CAGGTAGAGCGGGAAAAGGCCATTCTTTTGGCCAACCTACAGGAGTCACAGACACAGCTGGAACACACCAAGGGGGCACTGACGGAGCAG
CATGAGCGGGTGCACCGGCTCACAGAGCACGTCAATGCCATGAGGGGCCTGCAAAGCAGCAAGGAGCTCAAGGCTGAGCTGGACGGGGAG
AAGGGCCGGGACTCAGGGGAGGAGGCCCATGACTATGAGGTGGACATCAATGGTTTAGAGATCCTTGAATGCAAATACAGGGTGGCAGTA
ACTGAGGTGATTGATCTGAAAGCTGAAATTAAGGCCTTAAAGGAGAAATATAATAAATCTGTAGAAAACTACACTGATGAGAAGGCCAAG
TATGAGAGTAAAATCCAGATGTATGATGAGCAGGTGACAAGCCTTGAGAAGACCACCAAGGAGAGTGGTGAGAAGATGGCCCACATGGAG
AAGGAGTTGCAAAAGATGACCAGCATAGCCAACGAAAATCACAGTACCCTTAATACGGCCCAGGATGAGTTAGTGACATTCAGTGAGGAG
TTAGCTCAGCTTTACCACCATGTGTGTCTATGTAATAATGAAACTCCCAACAGGGTCATGCTGGATTACTATAGGCAGAGCAGAGTCACC
CGCAGTGGCAGCCTGAAAGGGCCCGATGATCCCAGAGGACTTTTGTCCCCACGATTAGCCAGGCGGGGTGTGTCATCCCCGGTAGAAACA
AGGACCTCATCTGAACCAGTTGCAAAAGAAAGCACAGAGGCCAGCAAAGAACCAAGTCCAACTAAGACCCCCACAATCTCTCCTGTTATT
ACTGCCCCACCGTCATCTCCAGTATTGGATACAAGTGACATCCGCAAAGAGCCAATGAATATCTACAACCTTAATGCCATAATCCGGGAC
CAAATCAAGCATCTGCAGAAAGCTGTGGACCGGTCCTTGCAACTGTCTCGTCAAAGAGCAGCGGCTCGGGAGCTAGCCCCCATGATTGAT
AAAGACAAGGAAGCCTTAATGGAAGAGATCCTCAAGCTAAAGTCCCTGCTGAGCACCAAACGGGAGCAGATCGCCACATTGAGGGCGGTG
TTGAAAGCCAACAAGCAGACAGCTGAGGTGGCGCTAGCTAATCTCAAGAACAAATATGAAAATGAAAAAGCAATGGTGACTGAAACCATG
ACGAAGCTTAGAAATGAACTGAAGGCTTTGAAAGAAGATGCTGCAACCTTCTCATCCCTGAGAGCAATGTTTGCAACAAGATGTGATGAA
TATGTCACCCAGTTGGATGAGATGCAGAGACAGTTAGCAGCTGCAGAGGATGAGAAGAAGACTCTGAACACTTTGTTACGAATGGCTATC
CAGCAAAAACTCGCCCTGACCCAGAGGCTGGAGGACTTAGAGTTTGACCATGAGCAGTCCCGACGCAGCAAAGGCAAACTTGGAAAGAGC
AAGATCGGCAGCCCTAAAGTAAGTGGGGAGGCATCAGTCACCGTGCCCACCATAGACACTTACCTCCTGCATAGTCAGGGCCCACAGACA
CCCAACATTCGGGTCAGCAGTGGCACTCAGAGGAAAAGACAATTTTCACCTTCCCTTTGTGATCAGAGCCGTCCCAGGACTTCAGGGGCT
TCCTACCTACAGAATTTATTAAGAGTTCCCCCTGATCCCACCTCCACAGAATCATTTCTTCTGAAGGGCCCCCCTTCCATGAGTGAATTC
ATCCAAGGGCACCGGCTCAGCAAGGAAAAAAGGTTAACCGTGGCTCCACCAGATTGTCAGCAGCCTGCTGCCTCCGTACCGCCACAGTGC
TCACAACTAGCCGGGAGGCAAGACTGCCCAACTGTCAGTCCTGACACAGCTCTCCCTGAGGAGCAGCCACATTCCAGCTCCCAGTGCGCC
CCTCTCCACTGTCTCTCCAAGCCTCCTCACCCCTAGTCTTCATCTCCTGTGGACGAACATCTGGGGTGGAAGTTTTGTAGCCACACACAG
GATACTGCCCAAGATCCAGCGGGTGTTTTCTTCTCGGTTGTTAGATGTACAATTGGATTAATGTCCATCGTTTTGGAAGACGAGAGAAAG
TTGAGAAGAACACGAAGCACAGACCCTGATGTGATAAAACATTTTGTGGTTTCTCTGAGTCACAGATAAACTTCTGCCATCAAATGGCTA

>4869_4869_3_ANO2-BICD1_ANO2_chr12_6030206_ENST00000356134_BICD1_chr12_32446928_ENST00000281474_length(amino acids)=1007AA_BP=174
MPEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGESTRSSSVINNYLDANEPVSLEARLSRMHFHD
SQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENNEMVE
LQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETL
KNEREQKNNLRKELSQYISLNDNHISISVDGLKFAEDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLRKGESLNPVSDLFSELNISEIQK
LKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKAELDGEKGRDSGEEAHDYEVDINGLEILEC
KYRVAVTEVIDLKAEIKALKEKYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQDEL
VTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVETRTSSEPVAKESTEASKEPSPTKTP
TISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQI
ATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNT
LLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSGEASVTVPTIDTYLLHSQGPQTPNIRVSSGTQRKRQFSPSLCDQSR
PRTSGASYLQNLLRVPPDPTSTESFLLKGPPSMSEFIQGHRLSKEKRLTVAPPDCQQPAASVPPQCSQLAGRQDCPTVSPDTALPEEQPH

--------------------------------------------------------------
>4869_4869_4_ANO2-BICD1_ANO2_chr12_6030206_ENST00000356134_BICD1_chr12_32446928_ENST00000548411_length(transcript)=8798nt_BP=594nt
CCAGGCTCCTTCTCTATAAAGTGGGATCTATCATGACCAGCCTACCTTATCAATATAGGAGAGAAAATCTTCATGCCTGAAGATATACCC
CTGCTCCCTGGCTCCCCACGCCGGCTGAGCCCTCAGGCAGGGTCCAGAGGGGGCCAGGGCCCCAAACATGGACAGCAGTGTCTCAAGATG
CCAGGTCCCCGGGCCCCAGGTCTGCAGGGCGGTTCCAACAGAGATCCTGGCCAGCCCTGCGGTGGAGAGAGCACCCGCAGCAGCTCTGTC
ATCAACAACTATCTGGATGCCAATGAGCCTGTGTCCTTGGAGGCCCGTCTTAGCCGCATGCACTTCCATGACAGTCAGAGGAAGGTCGAC
TATGTACTTGCCTACCACTACCGGAAACGCGGGGTGCACCTGGCCCAAGGCTTCCCTGGCCACTCGCTGGCTATCGTCTCCAATGGGGAG
ACAGGCAAGGAGCCTCATGCTGGGGGCCCAGGTGACATTGAGCTGGGACCGCTCGATGCCCTGGAGGAGGAGAGGAAGGAGCAGCGGGAG
GAATTTGAGCACAATCTGATGGAGGCTGGACTGGAGCTTGAGAAGGACTTGGAGAACAATGAGATGGTGGAGCTACAGAGAATACGGATG
AAGGATGAAATCCGAGAATATAAGTTCCGGGAGGCACGGCTCCTTCAGGACTATACTGAATTGGAAGAAGAAAATATCACATTGCAGAAA
CTAGTGTCCACGTTGAAGCAGAACCAGGTTGAATACGAAGGCTTAAAGCATGAGATTAAGCGATTTGAGGAGGAGACGGTACTGCTGAAC
AGCCAGCTGGAAGATGCCATCCGATTGAAAGAGATTGCTGAGCACCAACTGGAAGAAGCCCTCGAGACTTTAAAAAATGAAAGAGAGCAA
AAGAACAACCTGCGGAAGGAGCTCTCCCAGTATATCAGCCTCAATGATAACCATATCAGCATCTCAGTAGATGGACTCAAATTTGCCGAG
GATGGGAGTGAACCAAACAATGATGACAAAATGAACGGTCATATCCATGGGCCTCTTGTGAAACTGAATGGAGACTATCGGACTCCCACC
TTAAGGAAAGGAGAGTCTCTGAACCCTGTCTCTGACTTATTCAGTGAGCTGAACATTTCAGAAATACAGAAGTTGAAGCAGCAGCTTATG
CAGGTAGAGCGGGAAAAGGCCATTCTTTTGGCCAACCTACAGGAGTCACAGACACAGCTGGAACACACCAAGGGGGCACTGACGGAGCAG
CATGAGCGGGTGCACCGGCTCACAGAGCACGTCAATGCCATGAGGGGCCTGCAAAGCAGCAAGGAGCTCAAGGCTGAGCTGGACGGGGAG
AAGGGCCGGGACTCAGGGGAGGAGGCCCATGACTATGAGGTGGACATCAATGGTTTAGAGATCCTTGAATGCAAATACAGGGTGGCAGTA
ACTGAGGTGATTGATCTGAAAGCTGAAATTAAGGCCTTAAAGGAGAAATATAATAAATCTGTAGAAAACTACACTGATGAGAAGGCCAAG
TATGAGAGTAAAATCCAGATGTATGATGAGCAGGTGACAAGCCTTGAGAAGACCACCAAGGAGAGTGGTGAGAAGATGGCCCACATGGAG
AAGGAGTTGCAAAAGATGACCAGCATAGCCAACGAAAATCACAGTACCCTTAATACGGCCCAGGATGAGTTAGTGACATTCAGTGAGGAG
TTAGCTCAGCTTTACCACCATGTGTGTCTATGTAATAATGAAACTCCCAACAGGGTCATGCTGGATTACTATAGGCAGAGCAGAGTCACC
CGCAGTGGCAGCCTGAAAGGGCCCGATGATCCCAGAGGACTTTTGTCCCCACGATTAGCCAGGCGGGGTGTGTCATCCCCGGTAGAAACA
AGGACCTCATCTGAACCAGTTGCAAAAGAAAGCACAGAGGCCAGCAAAGAACCAAGTCCAACTAAGACCCCCACAATCTCTCCTGTTATT
ACTGCCCCACCGTCATCTCCAGTATTGGATACAAGTGACATCCGCAAAGAGCCAATGAATATCTACAACCTTAATGCCATAATCCGGGAC
CAAATCAAGCATCTGCAGAAAGCTGTGGACCGGTCCTTGCAACTGTCTCGTCAAAGAGCAGCGGCTCGGGAGCTAGCCCCCATGATTGAT
AAAGACAAGGAAGCCTTAATGGAAGAGATCCTCAAGCTAAAGTCCCTGCTGAGCACCAAACGGGAGCAGATCGCCACATTGAGGGCGGTG
TTGAAAGCCAACAAGCAGACAGCTGAGGTGGCGCTAGCTAATCTCAAGAACAAATATGAAAATGAAAAAGCAATGGTGACTGAAACCATG
ACGAAGCTTAGAAATGAACTGAAGGCTTTGAAAGAAGATGCTGCAACCTTCTCATCCCTGAGAGCAATGTTTGCAACAAGATGTGATGAA
TATGTCACCCAGTTGGATGAGATGCAGAGACAGTTAGCAGCTGCAGAGGATGAGAAGAAGACTCTGAACACTTTGTTACGAATGGCTATC
CAGCAAAAACTCGCCCTGACCCAGAGGCTGGAGGACTTAGAGTTTGACCATGAGCAGTCCCGACGCAGCAAAGGCAAACTTGGAAAGAGC
AAGATCGGCAGCCCTAAAATTGTCAGCAGCCTGCTGCCTCCGTACCGCCACAGTGCTCACAACTAGCCGGGAGGCAAGACTGCCCAACTG
TCAGTCCTGACACAGCTCTCCCTGAGGAGCAGCCACATTCCAGCTCCCAGTGCGCCCCTCTCCACTGTCTCTCCAAGCCTCCTCACCCCT
AGTCTTCATCTCCTGTGGACGAACATCTGGGGTGGAAGTTTTGTAGCCACACACAGGATACTGCCCAAGATCCAGCGGGTGTTTTCTTCT
CGGTTGTTAGATGTACAATTGGATTAATGTCCATCGTTTTGGAAGACGAGAGAAAGTTGAGAAGAACACGAAGCACAGACCCTGATGTGA
TAAAACATTTTGTGGTTTCTCTGAGTCACAGATAAACTTCTGCCATCAAATGGCTACAGTTCATTTAAATTTAAAAAAAAGAAAAAAGAA
ACAGAAAACGTGTCTCAGATGGCTGGCTTTACCTCGATAGCATAAGAGAGACCTAAGACATGTAAAATACGTATATTGCAGTATCATCTT
TCCTCACACTCCAAATTCAGCTAGGGAAGTTGATTCCAATATGTTTGTCATTGATATTTATTTTGTACTTTATTTGCTACATGATTTATG
TCTATACAAATAATTTCTCTGAGGTGAATTTAATTCATTTATTTTCAAATAAGCATAATTTGCTCAATTAAGTATGAGTTTGAATTTAGT
TTGAAATCTGGAATTGGCCAGACTGTGGTCATTTTTCTTGCACAAAATGATAAATGAGGTGCATCAGAATGTTAACAATAACTGTATTTT
GCTGCTACGCTGGTATTGTTTAGGCACTTACTTTCTAATCAGTAGCTCATTAACTGCTGGGTTTTGTTTTTGTATTTTTAACTAGAGTTC
TTCACTGGACATTACTAAGTAAATCTAAGAAAGAGACTAAGTTATGATTTATTGACTTATTCAAGTTTTGATGGCATCTTTACTTTTATT
TTTTCATTGCAGTTGAGTAGATGTACTGGTGCTGCTCCTTTGTATGTGTGTATGTGTGTGATAACGTTAAAGAAGGCTCAATAACTTGAA
GGGAAAAAAATGGTGTGTTTATTTAATGACCAGAATTTTTTTTACTTCTCCCAAAATCAGGGTCCTACTGAGTCTTTCCTGATAAAAGGT
ATCAAGTACAAATGGGAAAATATATACATATATAGATGTAAGATAGCCTTTAATTAATTAATTTACCCAGAGAGTGTTCAAAGTTTGATT
AAAATTGTATGTTTTGTTGTTGTTAGTTTTTTTCATAACGAATCTTCCTTGCCAAAAAAACAATAGATAATAAACCTTAGCTCATTGTCT
ACTTTTGACAAACACTCAGGTGCCTACAAACATTCTATTATCTTGAGATAATACATGTTCCTGGTTAATTTACAGATTCTGCTGGGTAAC
TTTTATGACTTGATTTAAGGCAGTGGATTTTCATAGCAAAATTTATTTTGCACATAATCTGACAAACAAGGAAAACAGCTAACTGAGCTG
AAAGGTCTAACACTCTCGGGCTCCTTAACCATCAAGTGCTGCCCACACAATTGCTCCTAGCCCTGATTCCTTGTCTTTGTCAGGTAGCCT
TAACTTATTTAAAACCATAAGGGTTTGACCTTTTCATATAAAGACATCTGTAACTTCTCTTCAAAACAAAAATGACCCTCACTGTTAACA
CAAAGGACAGTTACCAGTGTAGGGCACTGAGAAAGGAGATCCAGGAGCCACTCAGCTTATTGAGCGGACATGGGTGGCACAGAAATGGAG
TGGTCCATCAGAGACCAAATGGTAAGTCGTAAAGCACATTGCAGGAGCTTTCGTTAGTCATACGCCTATTAAGTAGTGGTCGCTATTACC
AAAGCAACCAGGACGTTTTGTGTTCTTTATATGAGTGCTATTTTCCACAGTGTCATTTATTATGCAACGTGGAGTAAAGAGTTGAAATCT
TCACCAAAATAAGGGTTCAGGTTAAAGTACAGAAACAGAAACAAAACGATTCGACATGAAGTTCCCAACCATAGCAGCCTAACCTTCTGC
TCTTTTCTACCTGCATGGCCTTGCTGTTCCTAAACATTGTCTTCATTTCACTGGCGTTGTATCTGCCTAGTACCAGTATTAGTGAGACTG
TGGATTTTATCAGAGTTCAATGAAAGAAAGCTTACCCCTGCCCTCACTTTGTGTTTTTTATTTTTCCCCCTTTCTCAAGCACCACGTATT
TGGACCTGAGAAGTGGCATAGCTGCTAAGTTGACTTTTAATAAAAAACTGTTTGTGCCTGAGGGAAATATATGCCTTTTTAAAAAGTACC
TCAGAACATGTTCGTAGATCGTCTCATCGGTTTTGTTTGGTGGGACTGGGAGTTCAGCAGGAAGTATTGTCTGTGTGTGATGACGGGGCA
GTATTGCCAGTCGGCAATGTTGTATTTGCATTCTTTATCCCTAACTCTGAATCTAGGACTCCATGAAAAGCCGGGTCACCCACAAAACAT
TTCTTCCAATACAAAGTGTATTATTACGTCTATTATAAACTAGTTTCATTTCAGTTATTTATCTTCATAGAGTGGGAAAGTCTTTTTCTG
AAATACTAATTCTATGAAAATAATAATTTTAGTGAATCTTTGCCAAGAAGTTATAGAAACTTGGAAATAAATTTCTCATTTTCAGCACAA
AATTAAGTGATAGTCCCTAAGCAGTAAGAGAGAATACCATGTATTTACACTGTGGCATCATTTAGTATAGTTTACACTGAGCCATATTTA
TTTATAGGCATTTAAAGTGAATCAGTATGTGTAGTGTTGATAAAAATCAGTATCTGTAAAGATAACATCAGGAATTCAAAAGGAAATTGA
AAAGGGGCAGAACTAGTGAGAACCAAAAAGAATGAACTCCAGTAAGACTAATTGAAGACATACTTGGAGAGGAAAAATAAACAGCAGAAA
TGCACTAAAAAATACTGGCTAATTATTGCAAACAGAGTGAGCAAAGATTAATGCTAACTAGTAAAAGTAGTTAGCAAAGTAAACAGGTAG
TTTTTTAAAAGTAAGCACAATTACAATATTGAATAGTATGGAGAAATGCTTTTCTCCTGAGGATTTTCCTTAATCAAAAAATAAGAAGAA
GCAATAAATTGTCTTTGGCCTGAGTGCTGAGTGGCATAAATAAAGGAGCTTGGCTTAATCTTTCTGGTCCACACATAATCCATTAGATCC
CATTCATATATCCAACTCTGGATTCTAATAAAATAATTTGGAGAACTTTGAGAAAAAGGAAAACTGTTAAATAAGAAAAGACCTATTTAG
AAATTATACTTTAGTCTAACGAAGAGGAGGTACAATAGTAGTCTTCAAGAAAAGAATATTTAACAAATGATAGATATCAGCTATAGATAT
TGTTACTAAGTCTAGAATAAAAAAGGCTTCAGTGTGAAGGATGTATAGTAACTCTAGGAAAGAGATTTTTAACACTGGGAAATTAACGTG
GAAATTGATAATCATAAAGAATATTTGTTTTGTAAAAATTGAATATCATTGGTGGTCTAGTAAGTATTAAGTGGCAAGATAGGAGAATGC
ATTTCAGTTCTGGGAGCTCATAATCCTGTGATTCTTTTATTTTAAGTTTTAAAATACATTAAAATTTTACTGGTTAATCATAAAATATTT
TATATTTGAAAATAGGATGGCAATCTTTATTTTTCCAAGATATTTGTTGGAAAAAAATGATCGTTGGTATTATTTTTTCTTTCAGCTATA
TTCCATGGTATCTTTAAAATTGTTCAGAATATAGGACTTTTACTAAAAAAATTCAATTGTCAGAGTCTAAAAAAACAATGTCCTCAGGAA
TACTTCAGAAATAGAAGGTATGCAATCCCTTAGTGGGGGGCAAACACATTTCAGATTTCGTCTTTATTTAAAAGGATCTTCAGTCTACAA
CATTTGCTTTTTTCGTGCTTTGGAAAATATCCTTGTGCAGATAAGTTCTTCTGTTTGAAACAAGCATGAAACATTGGTCCAATAACCTAA
GAATGTGGAGATTTCTTGATATTCTGTATTAATTAAAGTTCTCTACATGTCTCAAATGGAGATCACAAAACATGAAAAGGAAGAAATGAA
ATATCTTTTCTTCTGGGATGAGTGTCAATTTTAATGTATAATTGTCATAATCAATCAGCCAAAAGTTACAATCTGTCCCTCAGAGACATT
GGGGGAAGCTGATGGATTTCCAGTAAGGAACTGTGGTGGGTTCAAACTCAGGCTGCCACAAATACATTGATATGGTAGGTAGGAAGTAGG
ACTAAATTTGAAAGAAACTTATGGGATAAAGTTCACAATTTTAAAAAGGTTGCCCTCCAGTTTTTTTGTTTGTTTATAAACTAGAGTGAT
TTTTAAGTAACCCTTATATTTAAGGCTGCAAAAAATGTACAAGAGTATGTTTTCAAGTAAAGGGAACATAATTCTTCAAAAAGCTGTTGA
ACTGGAGTTATGATAGGTTATGACAGAGAGCATGATCAGTGCTGATACTGACAAGTACTTTTTTACCTTAAAATCAACTTCTATGGAACT
ACAAGATCAATCTAGCTCCCGAGTGACATTTTCCATTGTCTGTAATAATGCCCTCGGATGAGTTGTGTCTAAAATTAAGTTCATCTTTAT
TTATATGCGAACTTAACTGCCATAGTCCCTAATGTATTGCGTTTGTAACCTGATCGTATTATGTTTACAGCTGAAAGATTTCATCTAGAC
ATGTCTTTCGTCCTTATTATTCAAAGTGTAATTGAAAGAGATATTTAGTATTAAGACATGTTCCCCAATTGAGAATTTTCCAGAATATTC
TACTTAAGAAGAAGAAGAGCAATTAACTGCCTTTAGTGTAAGGGCGAGAGTGCATAGAAATATGCAATGTAAAATGTTTGCATGAATTAT
TTCACATCATGTAAGCTTTCCCATATTCATAAGATGAACACTATAGAAGTCTCATTTCTCTGTGATCTTCTGTCCATTAGGAAAGTAAGG
AGATTGTTATCTATATCTAGTCTCCTTTCCATATTGAACTGCATGGCTCTAATCCTCAGTGTATTTTTATCCCTTCTCGAGTTATTTAAA
ATTTGCCCTATTTAAGCTGAAGCCTGGATAAACTGCTGAGCCAGATTATTCCTGTGATTGGAGTTTAATTGCTGTAGAACACTTGTTGAG
AACACATTTTTTACTTTTTTTCTTTCAGAATTATTCCTCAATCATTGTTCTCTAATGAAAACACCGAGAAGTAAATCTGGTGCTTCTTAG
TGTAAATATGTTTTTCTTTTTAAAAAGTCATTTTAAAACAAAGATGAGAGAACTATAAAGTAAGGGGAAATATCATTTTATTTAAAAATA
ATTATTCAATGATAGATAATGGAGATACAGAATGACTCATTGGGTTCATAGGTATGATTTGTGCAGCCAGTCTTAGAGGAAATACATCAT
TTTAACATTATTCCCACAAAATGTTAAAGCTCAATGGTTTGACTATGAGAGTCAAACAATTACTATTTGAAAATCTCTTATGACATTTTT
ATAATCTACTCTGTTTTTATTTGCATGATTATGCTTATGTGATGAACCATCCATGATTCTGATATTGTATTTCTTTCCAGTATTAACATG
TGTATTGTGTGGCCAACTCTGATTTGTACACCGTATTATTGTTGTAATGATTCAACTGTTCCTACATTTAATTGCAGTTTAATTATTATG
CCTTTTGGGGTTAAATGATGTGAAGTGTTTCCACCTACTGATAAATACCATATGAAAACACGACTAAAAGACTGATTTAAGAAACTTGTT
ATTTTTAAAAATATGAATTTCAAAAGAAATGTTCTCAAAGACACATGCATTTATTTTAAATTCAAAAAATTCTTATGAATTTATTATTGC
TTGTACTTTAACTTTTTTTATTGTAGACAATCCTAAGTGAATAATGTCTCATGGGAGAACACATGATATGTGCTTGTATTTGTGTAATCT
GATCATGCACTCAATGGTTGGAAAAGGCACTCCAGTGCTAAGAAAATAACCAGAAGCCAATATATCGATTCTTATATCTCGGTTTATGTT

>4869_4869_4_ANO2-BICD1_ANO2_chr12_6030206_ENST00000356134_BICD1_chr12_32446928_ENST00000548411_length(amino acids)=867AA_BP=174
MPEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGESTRSSSVINNYLDANEPVSLEARLSRMHFHD
SQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENNEMVE
LQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETL
KNEREQKNNLRKELSQYISLNDNHISISVDGLKFAEDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLRKGESLNPVSDLFSELNISEIQK
LKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKAELDGEKGRDSGEEAHDYEVDINGLEILEC
KYRVAVTEVIDLKAEIKALKEKYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQDEL
VTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVETRTSSEPVAKESTEASKEPSPTKTP
TISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQI
ATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNT

--------------------------------------------------------------
>4869_4869_5_ANO2-BICD1_ANO2_chr12_6030206_ENST00000546188_BICD1_chr12_32446928_ENST00000281474_length(transcript)=3346nt_BP=594nt
CCAGGCTCCTTCTCTATAAAGTGGGATCTATCATGACCAGCCTACCTTATCAATATAGGAGAGAAAATCTTCATGCCTGAAGATATACCC
CTGCTCCCTGGCTCCCCACGCCGGCTGAGCCCTCAGGCAGGGTCCAGAGGGGGCCAGGGCCCCAAACATGGACAGCAGTGTCTCAAGATG
CCAGGTCCCCGGGCCCCAGGTCTGCAGGGCGGTTCCAACAGAGATCCTGGCCAGCCCTGCGGTGGAGAGAGCACCCGCAGCAGCTCTGTC
ATCAACAACTATCTGGATGCCAATGAGCCTGTGTCCTTGGAGGCCCGTCTTAGCCGCATGCACTTCCATGACAGTCAGAGGAAGGTCGAC
TATGTACTTGCCTACCACTACCGGAAACGCGGGGTGCACCTGGCCCAAGGCTTCCCTGGCCACTCGCTGGCTATCGTCTCCAATGGGGAG
ACAGGCAAGGAGCCTCATGCTGGGGGCCCAGGTGACATTGAGCTGGGACCGCTCGATGCCCTGGAGGAGGAGAGGAAGGAGCAGCGGGAG
GAATTTGAGCACAATCTGATGGAGGCTGGACTGGAGCTTGAGAAGGACTTGGAGAACAATGAGATGGTGGAGCTACAGAGAATACGGATG
AAGGATGAAATCCGAGAATATAAGTTCCGGGAGGCACGGCTCCTTCAGGACTATACTGAATTGGAAGAAGAAAATATCACATTGCAGAAA
CTAGTGTCCACGTTGAAGCAGAACCAGGTTGAATACGAAGGCTTAAAGCATGAGATTAAGCGATTTGAGGAGGAGACGGTACTGCTGAAC
AGCCAGCTGGAAGATGCCATCCGATTGAAAGAGATTGCTGAGCACCAACTGGAAGAAGCCCTCGAGACTTTAAAAAATGAAAGAGAGCAA
AAGAACAACCTGCGGAAGGAGCTCTCCCAGTATATCAGCCTCAATGATAACCATATCAGCATCTCAGTAGATGGACTCAAATTTGCCGAG
GATGGGAGTGAACCAAACAATGATGACAAAATGAACGGTCATATCCATGGGCCTCTTGTGAAACTGAATGGAGACTATCGGACTCCCACC
TTAAGGAAAGGAGAGTCTCTGAACCCTGTCTCTGACTTATTCAGTGAGCTGAACATTTCAGAAATACAGAAGTTGAAGCAGCAGCTTATG
CAGGTAGAGCGGGAAAAGGCCATTCTTTTGGCCAACCTACAGGAGTCACAGACACAGCTGGAACACACCAAGGGGGCACTGACGGAGCAG
CATGAGCGGGTGCACCGGCTCACAGAGCACGTCAATGCCATGAGGGGCCTGCAAAGCAGCAAGGAGCTCAAGGCTGAGCTGGACGGGGAG
AAGGGCCGGGACTCAGGGGAGGAGGCCCATGACTATGAGGTGGACATCAATGGTTTAGAGATCCTTGAATGCAAATACAGGGTGGCAGTA
ACTGAGGTGATTGATCTGAAAGCTGAAATTAAGGCCTTAAAGGAGAAATATAATAAATCTGTAGAAAACTACACTGATGAGAAGGCCAAG
TATGAGAGTAAAATCCAGATGTATGATGAGCAGGTGACAAGCCTTGAGAAGACCACCAAGGAGAGTGGTGAGAAGATGGCCCACATGGAG
AAGGAGTTGCAAAAGATGACCAGCATAGCCAACGAAAATCACAGTACCCTTAATACGGCCCAGGATGAGTTAGTGACATTCAGTGAGGAG
TTAGCTCAGCTTTACCACCATGTGTGTCTATGTAATAATGAAACTCCCAACAGGGTCATGCTGGATTACTATAGGCAGAGCAGAGTCACC
CGCAGTGGCAGCCTGAAAGGGCCCGATGATCCCAGAGGACTTTTGTCCCCACGATTAGCCAGGCGGGGTGTGTCATCCCCGGTAGAAACA
AGGACCTCATCTGAACCAGTTGCAAAAGAAAGCACAGAGGCCAGCAAAGAACCAAGTCCAACTAAGACCCCCACAATCTCTCCTGTTATT
ACTGCCCCACCGTCATCTCCAGTATTGGATACAAGTGACATCCGCAAAGAGCCAATGAATATCTACAACCTTAATGCCATAATCCGGGAC
CAAATCAAGCATCTGCAGAAAGCTGTGGACCGGTCCTTGCAACTGTCTCGTCAAAGAGCAGCGGCTCGGGAGCTAGCCCCCATGATTGAT
AAAGACAAGGAAGCCTTAATGGAAGAGATCCTCAAGCTAAAGTCCCTGCTGAGCACCAAACGGGAGCAGATCGCCACATTGAGGGCGGTG
TTGAAAGCCAACAAGCAGACAGCTGAGGTGGCGCTAGCTAATCTCAAGAACAAATATGAAAATGAAAAAGCAATGGTGACTGAAACCATG
ACGAAGCTTAGAAATGAACTGAAGGCTTTGAAAGAAGATGCTGCAACCTTCTCATCCCTGAGAGCAATGTTTGCAACAAGATGTGATGAA
TATGTCACCCAGTTGGATGAGATGCAGAGACAGTTAGCAGCTGCAGAGGATGAGAAGAAGACTCTGAACACTTTGTTACGAATGGCTATC
CAGCAAAAACTCGCCCTGACCCAGAGGCTGGAGGACTTAGAGTTTGACCATGAGCAGTCCCGACGCAGCAAAGGCAAACTTGGAAAGAGC
AAGATCGGCAGCCCTAAAGTAAGTGGGGAGGCATCAGTCACCGTGCCCACCATAGACACTTACCTCCTGCATAGTCAGGGCCCACAGACA
CCCAACATTCGGGTCAGCAGTGGCACTCAGAGGAAAAGACAATTTTCACCTTCCCTTTGTGATCAGAGCCGTCCCAGGACTTCAGGGGCT
TCCTACCTACAGAATTTATTAAGAGTTCCCCCTGATCCCACCTCCACAGAATCATTTCTTCTGAAGGGCCCCCCTTCCATGAGTGAATTC
ATCCAAGGGCACCGGCTCAGCAAGGAAAAAAGGTTAACCGTGGCTCCACCAGATTGTCAGCAGCCTGCTGCCTCCGTACCGCCACAGTGC
TCACAACTAGCCGGGAGGCAAGACTGCCCAACTGTCAGTCCTGACACAGCTCTCCCTGAGGAGCAGCCACATTCCAGCTCCCAGTGCGCC
CCTCTCCACTGTCTCTCCAAGCCTCCTCACCCCTAGTCTTCATCTCCTGTGGACGAACATCTGGGGTGGAAGTTTTGTAGCCACACACAG
GATACTGCCCAAGATCCAGCGGGTGTTTTCTTCTCGGTTGTTAGATGTACAATTGGATTAATGTCCATCGTTTTGGAAGACGAGAGAAAG
TTGAGAAGAACACGAAGCACAGACCCTGATGTGATAAAACATTTTGTGGTTTCTCTGAGTCACAGATAAACTTCTGCCATCAAATGGCTA

>4869_4869_5_ANO2-BICD1_ANO2_chr12_6030206_ENST00000546188_BICD1_chr12_32446928_ENST00000281474_length(amino acids)=1007AA_BP=174
MPEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGESTRSSSVINNYLDANEPVSLEARLSRMHFHD
SQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENNEMVE
LQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETL
KNEREQKNNLRKELSQYISLNDNHISISVDGLKFAEDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLRKGESLNPVSDLFSELNISEIQK
LKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKAELDGEKGRDSGEEAHDYEVDINGLEILEC
KYRVAVTEVIDLKAEIKALKEKYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQDEL
VTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVETRTSSEPVAKESTEASKEPSPTKTP
TISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQI
ATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNT
LLRMAIQQKLALTQRLEDLEFDHEQSRRSKGKLGKSKIGSPKVSGEASVTVPTIDTYLLHSQGPQTPNIRVSSGTQRKRQFSPSLCDQSR
PRTSGASYLQNLLRVPPDPTSTESFLLKGPPSMSEFIQGHRLSKEKRLTVAPPDCQQPAASVPPQCSQLAGRQDCPTVSPDTALPEEQPH

--------------------------------------------------------------
>4869_4869_6_ANO2-BICD1_ANO2_chr12_6030206_ENST00000546188_BICD1_chr12_32446928_ENST00000548411_length(transcript)=8798nt_BP=594nt
CCAGGCTCCTTCTCTATAAAGTGGGATCTATCATGACCAGCCTACCTTATCAATATAGGAGAGAAAATCTTCATGCCTGAAGATATACCC
CTGCTCCCTGGCTCCCCACGCCGGCTGAGCCCTCAGGCAGGGTCCAGAGGGGGCCAGGGCCCCAAACATGGACAGCAGTGTCTCAAGATG
CCAGGTCCCCGGGCCCCAGGTCTGCAGGGCGGTTCCAACAGAGATCCTGGCCAGCCCTGCGGTGGAGAGAGCACCCGCAGCAGCTCTGTC
ATCAACAACTATCTGGATGCCAATGAGCCTGTGTCCTTGGAGGCCCGTCTTAGCCGCATGCACTTCCATGACAGTCAGAGGAAGGTCGAC
TATGTACTTGCCTACCACTACCGGAAACGCGGGGTGCACCTGGCCCAAGGCTTCCCTGGCCACTCGCTGGCTATCGTCTCCAATGGGGAG
ACAGGCAAGGAGCCTCATGCTGGGGGCCCAGGTGACATTGAGCTGGGACCGCTCGATGCCCTGGAGGAGGAGAGGAAGGAGCAGCGGGAG
GAATTTGAGCACAATCTGATGGAGGCTGGACTGGAGCTTGAGAAGGACTTGGAGAACAATGAGATGGTGGAGCTACAGAGAATACGGATG
AAGGATGAAATCCGAGAATATAAGTTCCGGGAGGCACGGCTCCTTCAGGACTATACTGAATTGGAAGAAGAAAATATCACATTGCAGAAA
CTAGTGTCCACGTTGAAGCAGAACCAGGTTGAATACGAAGGCTTAAAGCATGAGATTAAGCGATTTGAGGAGGAGACGGTACTGCTGAAC
AGCCAGCTGGAAGATGCCATCCGATTGAAAGAGATTGCTGAGCACCAACTGGAAGAAGCCCTCGAGACTTTAAAAAATGAAAGAGAGCAA
AAGAACAACCTGCGGAAGGAGCTCTCCCAGTATATCAGCCTCAATGATAACCATATCAGCATCTCAGTAGATGGACTCAAATTTGCCGAG
GATGGGAGTGAACCAAACAATGATGACAAAATGAACGGTCATATCCATGGGCCTCTTGTGAAACTGAATGGAGACTATCGGACTCCCACC
TTAAGGAAAGGAGAGTCTCTGAACCCTGTCTCTGACTTATTCAGTGAGCTGAACATTTCAGAAATACAGAAGTTGAAGCAGCAGCTTATG
CAGGTAGAGCGGGAAAAGGCCATTCTTTTGGCCAACCTACAGGAGTCACAGACACAGCTGGAACACACCAAGGGGGCACTGACGGAGCAG
CATGAGCGGGTGCACCGGCTCACAGAGCACGTCAATGCCATGAGGGGCCTGCAAAGCAGCAAGGAGCTCAAGGCTGAGCTGGACGGGGAG
AAGGGCCGGGACTCAGGGGAGGAGGCCCATGACTATGAGGTGGACATCAATGGTTTAGAGATCCTTGAATGCAAATACAGGGTGGCAGTA
ACTGAGGTGATTGATCTGAAAGCTGAAATTAAGGCCTTAAAGGAGAAATATAATAAATCTGTAGAAAACTACACTGATGAGAAGGCCAAG
TATGAGAGTAAAATCCAGATGTATGATGAGCAGGTGACAAGCCTTGAGAAGACCACCAAGGAGAGTGGTGAGAAGATGGCCCACATGGAG
AAGGAGTTGCAAAAGATGACCAGCATAGCCAACGAAAATCACAGTACCCTTAATACGGCCCAGGATGAGTTAGTGACATTCAGTGAGGAG
TTAGCTCAGCTTTACCACCATGTGTGTCTATGTAATAATGAAACTCCCAACAGGGTCATGCTGGATTACTATAGGCAGAGCAGAGTCACC
CGCAGTGGCAGCCTGAAAGGGCCCGATGATCCCAGAGGACTTTTGTCCCCACGATTAGCCAGGCGGGGTGTGTCATCCCCGGTAGAAACA
AGGACCTCATCTGAACCAGTTGCAAAAGAAAGCACAGAGGCCAGCAAAGAACCAAGTCCAACTAAGACCCCCACAATCTCTCCTGTTATT
ACTGCCCCACCGTCATCTCCAGTATTGGATACAAGTGACATCCGCAAAGAGCCAATGAATATCTACAACCTTAATGCCATAATCCGGGAC
CAAATCAAGCATCTGCAGAAAGCTGTGGACCGGTCCTTGCAACTGTCTCGTCAAAGAGCAGCGGCTCGGGAGCTAGCCCCCATGATTGAT
AAAGACAAGGAAGCCTTAATGGAAGAGATCCTCAAGCTAAAGTCCCTGCTGAGCACCAAACGGGAGCAGATCGCCACATTGAGGGCGGTG
TTGAAAGCCAACAAGCAGACAGCTGAGGTGGCGCTAGCTAATCTCAAGAACAAATATGAAAATGAAAAAGCAATGGTGACTGAAACCATG
ACGAAGCTTAGAAATGAACTGAAGGCTTTGAAAGAAGATGCTGCAACCTTCTCATCCCTGAGAGCAATGTTTGCAACAAGATGTGATGAA
TATGTCACCCAGTTGGATGAGATGCAGAGACAGTTAGCAGCTGCAGAGGATGAGAAGAAGACTCTGAACACTTTGTTACGAATGGCTATC
CAGCAAAAACTCGCCCTGACCCAGAGGCTGGAGGACTTAGAGTTTGACCATGAGCAGTCCCGACGCAGCAAAGGCAAACTTGGAAAGAGC
AAGATCGGCAGCCCTAAAATTGTCAGCAGCCTGCTGCCTCCGTACCGCCACAGTGCTCACAACTAGCCGGGAGGCAAGACTGCCCAACTG
TCAGTCCTGACACAGCTCTCCCTGAGGAGCAGCCACATTCCAGCTCCCAGTGCGCCCCTCTCCACTGTCTCTCCAAGCCTCCTCACCCCT
AGTCTTCATCTCCTGTGGACGAACATCTGGGGTGGAAGTTTTGTAGCCACACACAGGATACTGCCCAAGATCCAGCGGGTGTTTTCTTCT
CGGTTGTTAGATGTACAATTGGATTAATGTCCATCGTTTTGGAAGACGAGAGAAAGTTGAGAAGAACACGAAGCACAGACCCTGATGTGA
TAAAACATTTTGTGGTTTCTCTGAGTCACAGATAAACTTCTGCCATCAAATGGCTACAGTTCATTTAAATTTAAAAAAAAGAAAAAAGAA
ACAGAAAACGTGTCTCAGATGGCTGGCTTTACCTCGATAGCATAAGAGAGACCTAAGACATGTAAAATACGTATATTGCAGTATCATCTT
TCCTCACACTCCAAATTCAGCTAGGGAAGTTGATTCCAATATGTTTGTCATTGATATTTATTTTGTACTTTATTTGCTACATGATTTATG
TCTATACAAATAATTTCTCTGAGGTGAATTTAATTCATTTATTTTCAAATAAGCATAATTTGCTCAATTAAGTATGAGTTTGAATTTAGT
TTGAAATCTGGAATTGGCCAGACTGTGGTCATTTTTCTTGCACAAAATGATAAATGAGGTGCATCAGAATGTTAACAATAACTGTATTTT
GCTGCTACGCTGGTATTGTTTAGGCACTTACTTTCTAATCAGTAGCTCATTAACTGCTGGGTTTTGTTTTTGTATTTTTAACTAGAGTTC
TTCACTGGACATTACTAAGTAAATCTAAGAAAGAGACTAAGTTATGATTTATTGACTTATTCAAGTTTTGATGGCATCTTTACTTTTATT
TTTTCATTGCAGTTGAGTAGATGTACTGGTGCTGCTCCTTTGTATGTGTGTATGTGTGTGATAACGTTAAAGAAGGCTCAATAACTTGAA
GGGAAAAAAATGGTGTGTTTATTTAATGACCAGAATTTTTTTTACTTCTCCCAAAATCAGGGTCCTACTGAGTCTTTCCTGATAAAAGGT
ATCAAGTACAAATGGGAAAATATATACATATATAGATGTAAGATAGCCTTTAATTAATTAATTTACCCAGAGAGTGTTCAAAGTTTGATT
AAAATTGTATGTTTTGTTGTTGTTAGTTTTTTTCATAACGAATCTTCCTTGCCAAAAAAACAATAGATAATAAACCTTAGCTCATTGTCT
ACTTTTGACAAACACTCAGGTGCCTACAAACATTCTATTATCTTGAGATAATACATGTTCCTGGTTAATTTACAGATTCTGCTGGGTAAC
TTTTATGACTTGATTTAAGGCAGTGGATTTTCATAGCAAAATTTATTTTGCACATAATCTGACAAACAAGGAAAACAGCTAACTGAGCTG
AAAGGTCTAACACTCTCGGGCTCCTTAACCATCAAGTGCTGCCCACACAATTGCTCCTAGCCCTGATTCCTTGTCTTTGTCAGGTAGCCT
TAACTTATTTAAAACCATAAGGGTTTGACCTTTTCATATAAAGACATCTGTAACTTCTCTTCAAAACAAAAATGACCCTCACTGTTAACA
CAAAGGACAGTTACCAGTGTAGGGCACTGAGAAAGGAGATCCAGGAGCCACTCAGCTTATTGAGCGGACATGGGTGGCACAGAAATGGAG
TGGTCCATCAGAGACCAAATGGTAAGTCGTAAAGCACATTGCAGGAGCTTTCGTTAGTCATACGCCTATTAAGTAGTGGTCGCTATTACC
AAAGCAACCAGGACGTTTTGTGTTCTTTATATGAGTGCTATTTTCCACAGTGTCATTTATTATGCAACGTGGAGTAAAGAGTTGAAATCT
TCACCAAAATAAGGGTTCAGGTTAAAGTACAGAAACAGAAACAAAACGATTCGACATGAAGTTCCCAACCATAGCAGCCTAACCTTCTGC
TCTTTTCTACCTGCATGGCCTTGCTGTTCCTAAACATTGTCTTCATTTCACTGGCGTTGTATCTGCCTAGTACCAGTATTAGTGAGACTG
TGGATTTTATCAGAGTTCAATGAAAGAAAGCTTACCCCTGCCCTCACTTTGTGTTTTTTATTTTTCCCCCTTTCTCAAGCACCACGTATT
TGGACCTGAGAAGTGGCATAGCTGCTAAGTTGACTTTTAATAAAAAACTGTTTGTGCCTGAGGGAAATATATGCCTTTTTAAAAAGTACC
TCAGAACATGTTCGTAGATCGTCTCATCGGTTTTGTTTGGTGGGACTGGGAGTTCAGCAGGAAGTATTGTCTGTGTGTGATGACGGGGCA
GTATTGCCAGTCGGCAATGTTGTATTTGCATTCTTTATCCCTAACTCTGAATCTAGGACTCCATGAAAAGCCGGGTCACCCACAAAACAT
TTCTTCCAATACAAAGTGTATTATTACGTCTATTATAAACTAGTTTCATTTCAGTTATTTATCTTCATAGAGTGGGAAAGTCTTTTTCTG
AAATACTAATTCTATGAAAATAATAATTTTAGTGAATCTTTGCCAAGAAGTTATAGAAACTTGGAAATAAATTTCTCATTTTCAGCACAA
AATTAAGTGATAGTCCCTAAGCAGTAAGAGAGAATACCATGTATTTACACTGTGGCATCATTTAGTATAGTTTACACTGAGCCATATTTA
TTTATAGGCATTTAAAGTGAATCAGTATGTGTAGTGTTGATAAAAATCAGTATCTGTAAAGATAACATCAGGAATTCAAAAGGAAATTGA
AAAGGGGCAGAACTAGTGAGAACCAAAAAGAATGAACTCCAGTAAGACTAATTGAAGACATACTTGGAGAGGAAAAATAAACAGCAGAAA
TGCACTAAAAAATACTGGCTAATTATTGCAAACAGAGTGAGCAAAGATTAATGCTAACTAGTAAAAGTAGTTAGCAAAGTAAACAGGTAG
TTTTTTAAAAGTAAGCACAATTACAATATTGAATAGTATGGAGAAATGCTTTTCTCCTGAGGATTTTCCTTAATCAAAAAATAAGAAGAA
GCAATAAATTGTCTTTGGCCTGAGTGCTGAGTGGCATAAATAAAGGAGCTTGGCTTAATCTTTCTGGTCCACACATAATCCATTAGATCC
CATTCATATATCCAACTCTGGATTCTAATAAAATAATTTGGAGAACTTTGAGAAAAAGGAAAACTGTTAAATAAGAAAAGACCTATTTAG
AAATTATACTTTAGTCTAACGAAGAGGAGGTACAATAGTAGTCTTCAAGAAAAGAATATTTAACAAATGATAGATATCAGCTATAGATAT
TGTTACTAAGTCTAGAATAAAAAAGGCTTCAGTGTGAAGGATGTATAGTAACTCTAGGAAAGAGATTTTTAACACTGGGAAATTAACGTG
GAAATTGATAATCATAAAGAATATTTGTTTTGTAAAAATTGAATATCATTGGTGGTCTAGTAAGTATTAAGTGGCAAGATAGGAGAATGC
ATTTCAGTTCTGGGAGCTCATAATCCTGTGATTCTTTTATTTTAAGTTTTAAAATACATTAAAATTTTACTGGTTAATCATAAAATATTT
TATATTTGAAAATAGGATGGCAATCTTTATTTTTCCAAGATATTTGTTGGAAAAAAATGATCGTTGGTATTATTTTTTCTTTCAGCTATA
TTCCATGGTATCTTTAAAATTGTTCAGAATATAGGACTTTTACTAAAAAAATTCAATTGTCAGAGTCTAAAAAAACAATGTCCTCAGGAA
TACTTCAGAAATAGAAGGTATGCAATCCCTTAGTGGGGGGCAAACACATTTCAGATTTCGTCTTTATTTAAAAGGATCTTCAGTCTACAA
CATTTGCTTTTTTCGTGCTTTGGAAAATATCCTTGTGCAGATAAGTTCTTCTGTTTGAAACAAGCATGAAACATTGGTCCAATAACCTAA
GAATGTGGAGATTTCTTGATATTCTGTATTAATTAAAGTTCTCTACATGTCTCAAATGGAGATCACAAAACATGAAAAGGAAGAAATGAA
ATATCTTTTCTTCTGGGATGAGTGTCAATTTTAATGTATAATTGTCATAATCAATCAGCCAAAAGTTACAATCTGTCCCTCAGAGACATT
GGGGGAAGCTGATGGATTTCCAGTAAGGAACTGTGGTGGGTTCAAACTCAGGCTGCCACAAATACATTGATATGGTAGGTAGGAAGTAGG
ACTAAATTTGAAAGAAACTTATGGGATAAAGTTCACAATTTTAAAAAGGTTGCCCTCCAGTTTTTTTGTTTGTTTATAAACTAGAGTGAT
TTTTAAGTAACCCTTATATTTAAGGCTGCAAAAAATGTACAAGAGTATGTTTTCAAGTAAAGGGAACATAATTCTTCAAAAAGCTGTTGA
ACTGGAGTTATGATAGGTTATGACAGAGAGCATGATCAGTGCTGATACTGACAAGTACTTTTTTACCTTAAAATCAACTTCTATGGAACT
ACAAGATCAATCTAGCTCCCGAGTGACATTTTCCATTGTCTGTAATAATGCCCTCGGATGAGTTGTGTCTAAAATTAAGTTCATCTTTAT
TTATATGCGAACTTAACTGCCATAGTCCCTAATGTATTGCGTTTGTAACCTGATCGTATTATGTTTACAGCTGAAAGATTTCATCTAGAC
ATGTCTTTCGTCCTTATTATTCAAAGTGTAATTGAAAGAGATATTTAGTATTAAGACATGTTCCCCAATTGAGAATTTTCCAGAATATTC
TACTTAAGAAGAAGAAGAGCAATTAACTGCCTTTAGTGTAAGGGCGAGAGTGCATAGAAATATGCAATGTAAAATGTTTGCATGAATTAT
TTCACATCATGTAAGCTTTCCCATATTCATAAGATGAACACTATAGAAGTCTCATTTCTCTGTGATCTTCTGTCCATTAGGAAAGTAAGG
AGATTGTTATCTATATCTAGTCTCCTTTCCATATTGAACTGCATGGCTCTAATCCTCAGTGTATTTTTATCCCTTCTCGAGTTATTTAAA
ATTTGCCCTATTTAAGCTGAAGCCTGGATAAACTGCTGAGCCAGATTATTCCTGTGATTGGAGTTTAATTGCTGTAGAACACTTGTTGAG
AACACATTTTTTACTTTTTTTCTTTCAGAATTATTCCTCAATCATTGTTCTCTAATGAAAACACCGAGAAGTAAATCTGGTGCTTCTTAG
TGTAAATATGTTTTTCTTTTTAAAAAGTCATTTTAAAACAAAGATGAGAGAACTATAAAGTAAGGGGAAATATCATTTTATTTAAAAATA
ATTATTCAATGATAGATAATGGAGATACAGAATGACTCATTGGGTTCATAGGTATGATTTGTGCAGCCAGTCTTAGAGGAAATACATCAT
TTTAACATTATTCCCACAAAATGTTAAAGCTCAATGGTTTGACTATGAGAGTCAAACAATTACTATTTGAAAATCTCTTATGACATTTTT
ATAATCTACTCTGTTTTTATTTGCATGATTATGCTTATGTGATGAACCATCCATGATTCTGATATTGTATTTCTTTCCAGTATTAACATG
TGTATTGTGTGGCCAACTCTGATTTGTACACCGTATTATTGTTGTAATGATTCAACTGTTCCTACATTTAATTGCAGTTTAATTATTATG
CCTTTTGGGGTTAAATGATGTGAAGTGTTTCCACCTACTGATAAATACCATATGAAAACACGACTAAAAGACTGATTTAAGAAACTTGTT
ATTTTTAAAAATATGAATTTCAAAAGAAATGTTCTCAAAGACACATGCATTTATTTTAAATTCAAAAAATTCTTATGAATTTATTATTGC
TTGTACTTTAACTTTTTTTATTGTAGACAATCCTAAGTGAATAATGTCTCATGGGAGAACACATGATATGTGCTTGTATTTGTGTAATCT
GATCATGCACTCAATGGTTGGAAAAGGCACTCCAGTGCTAAGAAAATAACCAGAAGCCAATATATCGATTCTTATATCTCGGTTTATGTT

>4869_4869_6_ANO2-BICD1_ANO2_chr12_6030206_ENST00000546188_BICD1_chr12_32446928_ENST00000548411_length(amino acids)=867AA_BP=174
MPEDIPLLPGSPRRLSPQAGSRGGQGPKHGQQCLKMPGPRAPGLQGGSNRDPGQPCGGESTRSSSVINNYLDANEPVSLEARLSRMHFHD
SQRKVDYVLAYHYRKRGVHLAQGFPGHSLAIVSNGETGKEPHAGGPGDIELGPLDALEEERKEQREEFEHNLMEAGLELEKDLENNEMVE
LQRIRMKDEIREYKFREARLLQDYTELEEENITLQKLVSTLKQNQVEYEGLKHEIKRFEEETVLLNSQLEDAIRLKEIAEHQLEEALETL
KNEREQKNNLRKELSQYISLNDNHISISVDGLKFAEDGSEPNNDDKMNGHIHGPLVKLNGDYRTPTLRKGESLNPVSDLFSELNISEIQK
LKQQLMQVEREKAILLANLQESQTQLEHTKGALTEQHERVHRLTEHVNAMRGLQSSKELKAELDGEKGRDSGEEAHDYEVDINGLEILEC
KYRVAVTEVIDLKAEIKALKEKYNKSVENYTDEKAKYESKIQMYDEQVTSLEKTTKESGEKMAHMEKELQKMTSIANENHSTLNTAQDEL
VTFSEELAQLYHHVCLCNNETPNRVMLDYYRQSRVTRSGSLKGPDDPRGLLSPRLARRGVSSPVETRTSSEPVAKESTEASKEPSPTKTP
TISPVITAPPSSPVLDTSDIRKEPMNIYNLNAIIRDQIKHLQKAVDRSLQLSRQRAAARELAPMIDKDKEALMEEILKLKSLLSTKREQI
ATLRAVLKANKQTAEVALANLKNKYENEKAMVTETMTKLRNELKALKEDAATFSSLRAMFATRCDEYVTQLDEMQRQLAAAEDEKKTLNT

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Fusion Gene PPI Analysis for ANO2-BICD1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANO2-BICD1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANO2-BICD1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource