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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:ANO6-IAPP (FusionGDB2 ID:4901) |
Fusion Gene Summary for ANO6-IAPP |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: ANO6-IAPP | Fusion gene ID: 4901 | Hgene | Tgene | Gene symbol | ANO6 | IAPP | Gene ID | 196527 | 3375 |
| Gene name | anoctamin 6 | islet amyloid polypeptide | |
| Synonyms | BDPLT7|SCTS|TMEM16F | DAP|IAP | |
| Cytomap | 12q12 | 12p12.1 | |
| Type of gene | protein-coding | protein-coding | |
| Description | anoctamin-6SCAN channelsmall-conductance calcium-activated nonselective cation channeltransmembrane protein 16F | islet amyloid polypeptideIslet amyloid polypeptide (diabetes-associated peptide; amylin)amylindiabetes-associated peptideinsulinoma amyloid peptide | |
| Modification date | 20200313 | 20200315 | |
| UniProtAcc | Q4KMQ2 | P10997 | |
| Ensembl transtripts involved in fusion gene | ENST00000320560, ENST00000423947, ENST00000425752, ENST00000435642, ENST00000441606, ENST00000426898, | ENST00000240652, ENST00000539393, ENST00000542023, | |
| Fusion gene scores | * DoF score | 8 X 8 X 6=384 | 5 X 5 X 5=125 |
| # samples | 10 | 7 | |
| ** MAII score | log2(10/384*10)=-1.94110631094643 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(7/125*10)=-0.836501267717121 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | |
| Context | PubMed: ANO6 [Title/Abstract] AND IAPP [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | ANO6(45816845)-IAPP(21531171), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | ANO6-IAPP seems lost the major protein functional domain in Tgene partner, which is a essential gene due to the frame-shifted ORF. | ||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Hgene | ANO6 | GO:0006812 | cation transport | 22946059 |
| Fusion gene breakpoints across ANO6 (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across IAPP (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-E2-A1L8-01A | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| ChimerDB4 | BRCA | TCGA-E2-A1L8-01A | ANO6 | chr12 | 45816845 | - | IAPP | chr12 | 21531171 | + |
| ChimerDB4 | BRCA | TCGA-E2-A1L8-01A | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| ChimerDB4 | BRCA | TCGA-E2-A1L8 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
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Fusion Gene ORF analysis for ANO6-IAPP |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| Frame-shift | ENST00000320560 | ENST00000240652 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| Frame-shift | ENST00000320560 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| Frame-shift | ENST00000320560 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| Frame-shift | ENST00000423947 | ENST00000240652 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| Frame-shift | ENST00000423947 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| Frame-shift | ENST00000423947 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| Frame-shift | ENST00000425752 | ENST00000240652 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| Frame-shift | ENST00000425752 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| Frame-shift | ENST00000425752 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| Frame-shift | ENST00000435642 | ENST00000240652 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| Frame-shift | ENST00000435642 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| Frame-shift | ENST00000435642 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| Frame-shift | ENST00000441606 | ENST00000240652 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| Frame-shift | ENST00000441606 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| Frame-shift | ENST00000441606 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000320560 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000320560 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000320560 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000320560 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000320560 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000320560 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000423947 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000423947 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000423947 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000423947 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000423947 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000423947 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000425752 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000425752 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000425752 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000425752 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000425752 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000425752 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000435642 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000435642 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000435642 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000435642 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000435642 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000435642 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000441606 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000441606 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000441606 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000441606 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| In-frame | ENST00000441606 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| In-frame | ENST00000441606 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| intron-3CDS | ENST00000426898 | ENST00000240652 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| intron-3CDS | ENST00000426898 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| intron-3CDS | ENST00000426898 | ENST00000240652 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| intron-3CDS | ENST00000426898 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| intron-3CDS | ENST00000426898 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| intron-3CDS | ENST00000426898 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| intron-3CDS | ENST00000426898 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + |
| intron-3CDS | ENST00000426898 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + |
| intron-3CDS | ENST00000426898 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000425752 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531171 | + | 3087 | 2828 | 182 | 3037 | 951 |
| ENST00000425752 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531171 | + | 4570 | 2828 | 182 | 3037 | 951 |
| ENST00000423947 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531171 | + | 3085 | 2826 | 117 | 3035 | 972 |
| ENST00000423947 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531171 | + | 4568 | 2826 | 117 | 3035 | 972 |
| ENST00000435642 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531171 | + | 2977 | 2718 | 45 | 2927 | 960 |
| ENST00000435642 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531171 | + | 4460 | 2718 | 45 | 2927 | 960 |
| ENST00000320560 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531171 | + | 2987 | 2728 | 82 | 2937 | 951 |
| ENST00000320560 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531171 | + | 4470 | 2728 | 82 | 2937 | 951 |
| ENST00000441606 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531171 | + | 2967 | 2708 | 221 | 2917 | 898 |
| ENST00000441606 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531171 | + | 4450 | 2708 | 221 | 2917 | 898 |
| ENST00000425752 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 3087 | 2828 | 182 | 3037 | 951 |
| ENST00000425752 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4570 | 2828 | 182 | 3037 | 951 |
| ENST00000423947 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 3085 | 2826 | 117 | 3035 | 972 |
| ENST00000423947 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4568 | 2826 | 117 | 3035 | 972 |
| ENST00000435642 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 2977 | 2718 | 45 | 2927 | 960 |
| ENST00000435642 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4460 | 2718 | 45 | 2927 | 960 |
| ENST00000320560 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 2987 | 2728 | 82 | 2937 | 951 |
| ENST00000320560 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4470 | 2728 | 82 | 2937 | 951 |
| ENST00000441606 | ANO6 | chr12 | 45816845 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 2967 | 2708 | 221 | 2917 | 898 |
| ENST00000441606 | ANO6 | chr12 | 45816845 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4450 | 2708 | 221 | 2917 | 898 |
| ENST00000425752 | ANO6 | chr12 | 45816844 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 3087 | 2828 | 182 | 3037 | 951 |
| ENST00000425752 | ANO6 | chr12 | 45816844 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4570 | 2828 | 182 | 3037 | 951 |
| ENST00000423947 | ANO6 | chr12 | 45816844 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 3085 | 2826 | 117 | 3035 | 972 |
| ENST00000423947 | ANO6 | chr12 | 45816844 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4568 | 2826 | 117 | 3035 | 972 |
| ENST00000435642 | ANO6 | chr12 | 45816844 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 2977 | 2718 | 45 | 2927 | 960 |
| ENST00000435642 | ANO6 | chr12 | 45816844 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4460 | 2718 | 45 | 2927 | 960 |
| ENST00000320560 | ANO6 | chr12 | 45816844 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 2987 | 2728 | 82 | 2937 | 951 |
| ENST00000320560 | ANO6 | chr12 | 45816844 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4470 | 2728 | 82 | 2937 | 951 |
| ENST00000441606 | ANO6 | chr12 | 45816844 | + | ENST00000539393 | IAPP | chr12 | 21531170 | + | 2967 | 2708 | 221 | 2917 | 898 |
| ENST00000441606 | ANO6 | chr12 | 45816844 | + | ENST00000542023 | IAPP | chr12 | 21531170 | + | 4450 | 2708 | 221 | 2917 | 898 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000425752 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000505221 | 0.9994948 |
| ENST00000425752 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000181336 | 0.99981874 |
| ENST00000423947 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000345786 | 0.9996542 |
| ENST00000423947 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000119715 | 0.9998803 |
| ENST00000435642 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000490454 | 0.9995096 |
| ENST00000435642 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000174033 | 0.999826 |
| ENST00000320560 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000424523 | 0.99957544 |
| ENST00000320560 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000165026 | 0.9998349 |
| ENST00000441606 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000655959 | 0.99934405 |
| ENST00000441606 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531171 | + | 0.000350859 | 0.99964917 |
| ENST00000425752 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000505221 | 0.9994948 |
| ENST00000425752 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000181336 | 0.99981874 |
| ENST00000423947 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000345786 | 0.9996542 |
| ENST00000423947 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000119715 | 0.9998803 |
| ENST00000435642 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000490454 | 0.9995096 |
| ENST00000435642 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000174033 | 0.999826 |
| ENST00000320560 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000424523 | 0.99957544 |
| ENST00000320560 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000165026 | 0.9998349 |
| ENST00000441606 | ENST00000539393 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000655959 | 0.99934405 |
| ENST00000441606 | ENST00000542023 | ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.000350859 | 0.99964917 |
| ENST00000425752 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000505221 | 0.9994948 |
| ENST00000425752 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000181336 | 0.99981874 |
| ENST00000423947 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000345786 | 0.9996542 |
| ENST00000423947 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000119715 | 0.9998803 |
| ENST00000435642 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000490454 | 0.9995096 |
| ENST00000435642 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000174033 | 0.999826 |
| ENST00000320560 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000424523 | 0.99957544 |
| ENST00000320560 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000165026 | 0.9998349 |
| ENST00000441606 | ENST00000539393 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000655959 | 0.99934405 |
| ENST00000441606 | ENST00000542023 | ANO6 | chr12 | 45816844 | + | IAPP | chr12 | 21531170 | + | 0.000350859 | 0.99964917 |
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Fusion Genomic Features for ANO6-IAPP |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.26387757 | 0.7361224 |
| ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.26387757 | 0.7361224 |
| ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.26387757 | 0.7361224 |
| ANO6 | chr12 | 45816845 | + | IAPP | chr12 | 21531170 | + | 0.26387757 | 0.7361224 |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for ANO6-IAPP |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr12:45816845/chr12:21531171) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| ANO6 | IAPP |
| FUNCTION: Small-conductance calcium-activated nonselective cation (SCAN) channel which acts as a regulator of phospholipid scrambling in platelets and osteoblasts. Phospholipid scrambling results in surface exposure of phosphatidylserine which in platelets is essential to trigger the clotting system whereas in osteoblasts is essential for the deposition of hydroxyapatite during bone mineralization. Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Can generate outwardly rectifying chloride channel currents in airway epithelial cells and Jurkat T lymphocytes. {ECO:0000250|UniProtKB:Q6P9J9, ECO:0000269|PubMed:20056604, ECO:0000269|PubMed:21107324, ECO:0000269|PubMed:21908539, ECO:0000269|PubMed:22006324, ECO:0000269|PubMed:22946059}. | FUNCTION: Selectively inhibits insulin-stimulated glucose utilization and glycogen deposition in muscle, while not affecting adipocyte glucose metabolism. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 1_300 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 322_375 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 397_455 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 477_509 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 531_551 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 573_601 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 622_663 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 706_722 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 744_836 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 1_300 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 322_375 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 397_455 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 477_509 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 531_551 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 573_601 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 622_663 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 706_722 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 744_836 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 1_300 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 322_375 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 397_455 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 477_509 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 531_551 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 573_601 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 622_663 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 706_722 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 744_836 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 1_300 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 322_375 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 397_455 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 477_509 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 531_551 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 573_601 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 622_663 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 706_722 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 744_836 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 1_300 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 322_375 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 397_455 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 477_509 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 531_551 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 573_601 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 622_663 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 706_722 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 1_300 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 322_375 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 397_455 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 477_509 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 531_551 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 573_601 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 622_663 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 706_722 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 744_836 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 1_300 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 322_375 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 397_455 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 477_509 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 531_551 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 573_601 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 622_663 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 706_722 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 744_836 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 1_300 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 322_375 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 397_455 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 477_509 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 531_551 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 573_601 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 622_663 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 706_722 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 744_836 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 1_300 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 322_375 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 397_455 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 477_509 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 531_551 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 573_601 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 622_663 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 706_722 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 744_836 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 1_300 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 322_375 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 397_455 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 477_509 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 531_551 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 573_601 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 622_663 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 706_722 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 1_300 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 322_375 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 397_455 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 477_509 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 531_551 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 573_601 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 622_663 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 706_722 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 744_836 | 842 | 911.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 1_300 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 322_375 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 397_455 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 477_509 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 531_551 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 573_601 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 622_663 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 706_722 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 744_836 | 863 | 932.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 1_300 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 322_375 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 397_455 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 477_509 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 531_551 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 573_601 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 622_663 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 706_722 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 744_836 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 1_300 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 322_375 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 397_455 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 477_509 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 531_551 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 573_601 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 622_663 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 706_722 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 744_836 | 842 | 930.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 1_300 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 322_375 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 397_455 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 477_509 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 531_551 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 573_601 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 622_663 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 706_722 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 301_321 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 376_396 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 456_476 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 510_530 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 552_572 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 602_621 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 664_684 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 685_705 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 723_743 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 301_321 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 376_396 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 456_476 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 510_530 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 552_572 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 602_621 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 664_684 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 685_705 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 723_743 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 837_857 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 301_321 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 376_396 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 456_476 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 510_530 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 552_572 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 602_621 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 664_684 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 685_705 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 723_743 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 301_321 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 376_396 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 456_476 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 510_530 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 552_572 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 602_621 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 664_684 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 685_705 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 723_743 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 301_321 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 376_396 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 456_476 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 510_530 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 552_572 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 602_621 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 664_684 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 685_705 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 723_743 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 301_321 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 376_396 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 456_476 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 510_530 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 552_572 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 602_621 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 664_684 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 685_705 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 723_743 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 301_321 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 376_396 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 456_476 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 510_530 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 552_572 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 602_621 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 664_684 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 685_705 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 723_743 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 837_857 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 301_321 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 376_396 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 456_476 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 510_530 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 552_572 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 602_621 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 664_684 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 685_705 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 723_743 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 301_321 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 376_396 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 456_476 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 510_530 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 552_572 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 602_621 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 664_684 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 685_705 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 723_743 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 301_321 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 376_396 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 456_476 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 510_530 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 552_572 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 602_621 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 664_684 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 685_705 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 723_743 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 301_321 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 376_396 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 456_476 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 510_530 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 552_572 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 602_621 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 664_684 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 685_705 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 723_743 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 301_321 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 376_396 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 456_476 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 510_530 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 552_572 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 602_621 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 664_684 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 685_705 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 723_743 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 837_857 | 863 | 932.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 301_321 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 376_396 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 456_476 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 510_530 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 552_572 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 602_621 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 664_684 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 685_705 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 723_743 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 301_321 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 376_396 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 456_476 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 510_530 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 552_572 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 602_621 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 664_684 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 685_705 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 723_743 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 301_321 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 376_396 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 456_476 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 510_530 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 552_572 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 602_621 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 664_684 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 685_705 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 723_743 | 824 | 893.0 | Transmembrane | Helical |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 858_910 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 858_910 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 858_910 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 858_910 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 744_836 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 858_910 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 858_910 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000423947 | + | 20 | 21 | 858_910 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 858_910 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 858_910 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 744_836 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 858_910 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 858_910 | 842 | 911.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000423947 | + | 20 | 21 | 858_910 | 863 | 932.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 858_910 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 858_910 | 842 | 930.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 744_836 | 824 | 893.0 | Topological domain | Extracellular |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 858_910 | 824 | 893.0 | Topological domain | Cytoplasmic |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 837_857 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 837_857 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 837_857 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816844 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 837_857 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000320560 | + | 19 | 20 | 837_857 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000425752 | + | 19 | 20 | 837_857 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000435642 | + | 20 | 21 | 837_857 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531170 | ENST00000441606 | + | 19 | 20 | 837_857 | 824 | 893.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000320560 | + | 19 | 20 | 837_857 | 842 | 911.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000425752 | + | 19 | 20 | 837_857 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000435642 | + | 20 | 21 | 837_857 | 842 | 930.0 | Transmembrane | Helical |
| Hgene | ANO6 | chr12:45816845 | chr12:21531171 | ENST00000441606 | + | 19 | 20 | 837_857 | 824 | 893.0 | Transmembrane | Helical |
Top |
Fusion Gene Sequence for ANO6-IAPP |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >4901_4901_1_ANO6-IAPP_ANO6_chr12_45816844_ENST00000320560_IAPP_chr12_21531170_ENST00000539393_length(transcript)=2987nt_BP=2728nt GAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCC AAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTC GGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATAT CGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATT TAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGAC CAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAAC AAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAA ATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAG CATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTT CAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAA CAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAA TGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGA GAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGG ATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAG GCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGT ATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACA GCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTT TACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGAT CATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGAC TCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTAT GATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTA CTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGA AGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGA AGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTA CCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTC TTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCT GGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCAT AGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGA AGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCA TACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGC CAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATT TTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGG TTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTAT >4901_4901_1_ANO6-IAPP_ANO6_chr12_45816844_ENST00000320560_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_2_ANO6-IAPP_ANO6_chr12_45816844_ENST00000320560_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4470nt_BP=2728nt GAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCC AAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTC GGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATAT CGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATT TAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGAC CAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAAC AAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAA ATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAG CATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTT CAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAA CAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAA TGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGA GAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGG ATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAG GCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGT ATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACA GCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTT TACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGAT CATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGAC TCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTAT GATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTA CTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGA AGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGA AGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTA CCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTC TTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCT GGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCAT AGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGA AGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCA TACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGC CAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATT TTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGG TTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTAT AATTTAACAGTGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTCAAAAGATT GTTTTATATGTAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTATTTTAAAA CATAAGAACGTCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTAAATTGTAA ACAGCTAATAATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGA GGCCGAGGCAGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTA GCCGGGGGTGGTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAGGTTGCAGT GAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTGTAAGTACC CCTGATAAGCAAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTGTTTTAAAA ACAAAGAAATAAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAGGCTATTTA AAAGTATAAAACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTTATTTTGTT TAAGTGGCTTTCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAATTAAAAGA CCACAGACTTCTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGTATATGATA CACTTTTTTTGATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTTTCCCTGAC TTTGAGTTAGGTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCAACTTGTAC TTTTAAAAAAATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCCCTTTATGA AGTGTGCCTTAGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGAAATATATT >4901_4901_2_ANO6-IAPP_ANO6_chr12_45816844_ENST00000320560_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_3_ANO6-IAPP_ANO6_chr12_45816844_ENST00000423947_IAPP_chr12_21531170_ENST00000539393_length(transcript)=3085nt_BP=2826nt GGGCATGCTCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTC CCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTC TGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAA ATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGGTGATGTTCCTGCCTCCAGGAGGCCTTTTCTGACTCCTCATACTCACCTCCCA TCCAGCCTGGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTT GAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGA AAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTA GAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATG CACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTA GACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGAT GCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTT GGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGC TGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATAC TATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTT CTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAG TGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTC TTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTT GAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGC ATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTT ATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAA TACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTG GCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTC AACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATAC AGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAAC ATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAA CAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTT GTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTT AGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCC ATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTAC ACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTG GGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTG ATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCT GGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGC AGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATT >4901_4901_3_ANO6-IAPP_ANO6_chr12_45816844_ENST00000423947_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=972AA_BP=903 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIGDVPASRRPFLTPHTHLPSSLVLENLG QTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDD KLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRS RIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYF AWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWV TLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLS VFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYI AFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMG KLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDM IPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFII -------------------------------------------------------------- >4901_4901_4_ANO6-IAPP_ANO6_chr12_45816844_ENST00000423947_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4568nt_BP=2826nt GGGCATGCTCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTC CCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTC TGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAA ATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGGTGATGTTCCTGCCTCCAGGAGGCCTTTTCTGACTCCTCATACTCACCTCCCA TCCAGCCTGGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTT GAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGA AAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTA GAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATG CACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTA GACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGAT GCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTT GGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGC TGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATAC TATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTT CTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAG TGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTC TTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTT GAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGC ATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTT ATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAA TACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTG GCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTC AACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATAC AGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAAC ATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAA CAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTT GTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTT AGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCC ATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTAC ACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTG GGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTG ATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCT GGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGC AGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATT TCCTGTATAATTTAACAGTGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTC AAAAGATTGTTTTATATGTAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTA TTTTAAAACATAAGAACGTCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTA AATTGTAAACAGCTAATAATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCA CTTTGGGAGGCCGAGGCAGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATAC AAAAATTAGCCGGGGGTGGTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAG GTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTG TAAGTACCCCTGATAAGCAAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTG TTTTAAAAACAAAGAAATAAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAG GCTATTTAAAAGTATAAAACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTT ATTTTGTTTAAGTGGCTTTCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAA TTAAAAGACCACAGACTTCTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGT ATATGATACACTTTTTTTGATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTT TCCCTGACTTTGAGTTAGGTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCA ACTTGTACTTTTAAAAAAATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCC CTTTATGAAGTGTGCCTTAGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGA >4901_4901_4_ANO6-IAPP_ANO6_chr12_45816844_ENST00000423947_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=972AA_BP=903 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIGDVPASRRPFLTPHTHLPSSLVLENLG QTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDD KLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRS RIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYF AWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWV TLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLS VFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYI AFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMG KLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDM IPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFII -------------------------------------------------------------- >4901_4901_5_ANO6-IAPP_ANO6_chr12_45816844_ENST00000425752_IAPP_chr12_21531170_ENST00000539393_length(transcript)=3087nt_BP=2828nt CTTCTGCGCGCCTCGTAAAACCGGGGAAGTTCAATCATTCCGCAGCGAGCCGCGGCGGCCGCACTGGGCATGCTCAGTCTCCGGGCTCCG CTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGC CCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCG CGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACG ATGGGGATATCGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGT TTGAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCA GAAAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGT TAGAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAA TGCACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTG TAGACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAG ATGCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGT TTGGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCA GCTGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAAT ACTATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCT TTCTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTC AGTGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGG TCTTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTG TTGAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAAC GCATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAG TTATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGA AATACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAG TGGCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTG TCAACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAAT ACAGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATA ACATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGG AACAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTAT TTGTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGT TTAGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATG CCATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCT ACACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACC TGGGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATG TGATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGC CTGGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAAT GCAGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGA >4901_4901_5_ANO6-IAPP_ANO6_chr12_45816844_ENST00000425752_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_6_ANO6-IAPP_ANO6_chr12_45816844_ENST00000425752_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4570nt_BP=2828nt CTTCTGCGCGCCTCGTAAAACCGGGGAAGTTCAATCATTCCGCAGCGAGCCGCGGCGGCCGCACTGGGCATGCTCAGTCTCCGGGCTCCG CTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGC CCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCG CGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACG ATGGGGATATCGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGT TTGAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCA GAAAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGT TAGAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAA TGCACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTG TAGACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAG ATGCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGT TTGGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCA GCTGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAAT ACTATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCT TTCTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTC AGTGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGG TCTTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTG TTGAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAAC GCATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAG TTATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGA AATACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAG TGGCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTG TCAACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAAT ACAGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATA ACATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGG AACAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTAT TTGTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGT TTAGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATG CCATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCT ACACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACC TGGGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATG TGATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGC CTGGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAAT GCAGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGA TTTCCTGTATAATTTAACAGTGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTC TCAAAAGATTGTTTTATATGTAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTG TATTTTAAAACATAAGAACGTCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGG TAAATTGTAAACAGCTAATAATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAG CACTTTGGGAGGCCGAGGCAGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAAT ACAAAAATTAGCCGGGGGTGGTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGG AGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAAT TGTAAGTACCCCTGATAAGCAAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGC TGTTTTAAAAACAAAGAAATAAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAG AGGCTATTTAAAAGTATAAAACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCAT TTATTTTGTTTAAGTGGCTTTCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTC AATTAAAAGACCACAGACTTCTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTAT GTATATGATACACTTTTTTTGATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCT TTTCCCTGACTTTGAGTTAGGTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACT CAACTTGTACTTTTAAAAAAATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTT CCCTTTATGAAGTGTGCCTTAGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGG >4901_4901_6_ANO6-IAPP_ANO6_chr12_45816844_ENST00000425752_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_7_ANO6-IAPP_ANO6_chr12_45816844_ENST00000435642_IAPP_chr12_21531170_ENST00000539393_length(transcript)=2977nt_BP=2718nt TCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGC TGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCT TCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGTGTTGGAA AACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAA CCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAG GGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTA TTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTG AAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAG CCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCC ACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTA AACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTAC CTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGA ATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAAT CAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCA TTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGA GTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAA CAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGG GGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTAT AGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACA GCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAAC TTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGC TTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGAC CCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTG CCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAG CCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTG GCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAG AAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACG TCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATC AACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGC AGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCT TTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCA TTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAG AGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTATAATTTAACAG >4901_4901_7_ANO6-IAPP_ANO6_chr12_45816844_ENST00000435642_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=960AA_BP=891 MGSGRWVPRLGFPRRWLGSAAPEPKRHTPRGPRSAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLES QHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWE VLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKY QVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLL AAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQA ELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKN INGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPG DPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMI IQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSV PPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQ -------------------------------------------------------------- >4901_4901_8_ANO6-IAPP_ANO6_chr12_45816844_ENST00000435642_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4460nt_BP=2718nt TCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGC TGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCT TCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGTGTTGGAA AACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAA CCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAG GGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTA TTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTG AAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAG CCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCC ACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTA AACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTAC CTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGA ATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAAT CAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCA TTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGA GTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAA CAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGG GGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTAT AGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACA GCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAAC TTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGC TTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGAC CCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTG CCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAG CCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTG GCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAG AAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACG TCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATC AACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGC AGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCT TTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCA TTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAG AGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTATAATTTAACAG TGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTCAAAAGATTGTTTTATATG TAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTATTTTAAAACATAAGAACG TCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTAAATTGTAAACAGCTAATA ATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCA GGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGGGTG GTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGAT TGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTGTAAGTACCCCTGATAAGC AAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTGTTTTAAAAACAAAGAAAT AAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAGGCTATTTAAAAGTATAAA ACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTTATTTTGTTTAAGTGGCTT TCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAATTAAAAGACCACAGACTT CTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGTATATGATACACTTTTTTT GATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTTTCCCTGACTTTGAGTTAG GTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCAACTTGTACTTTTAAAAAA ATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCCCTTTATGAAGTGTGCCTT AGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGAAATATATTTATAATAAAT >4901_4901_8_ANO6-IAPP_ANO6_chr12_45816844_ENST00000435642_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=960AA_BP=891 MGSGRWVPRLGFPRRWLGSAAPEPKRHTPRGPRSAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLES QHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWE VLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKY QVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLL AAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQA ELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKN INGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPG DPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMI IQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSV PPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQ -------------------------------------------------------------- >4901_4901_9_ANO6-IAPP_ANO6_chr12_45816844_ENST00000441606_IAPP_chr12_21531170_ENST00000539393_length(transcript)=2967nt_BP=2708nt TTGGGGCAGAGGAGGCTTGTAGGAATAGGGGAAGAGTTCATAAGCAGAGCTGAAACAACACCAAACATGGAAATGTTACAAGGTGGAGAA ATTGTGCTTACTGAAACTCTTCTCAGAAATATTGCTGTTTGTGGATGATAGAAATCTTCAGAGTTGTCACTTAAGGTAGAGGTAGGAGGG TAAGAAGCGTCAAGGACTCACCGAATTGTCCATTCCCCCTTTTGTTCTGCTGTGGAATGTTTTGTGCTGCTGTGTTGGAAAACCTTGGAC AGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAACCTGACTCCC TCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAGGGTACAAATG AAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTATTGGATGACA AGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTGAAACCCAATG ATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAGCCAGAGCAAG AGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCCACCAGAAGCC GCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTAAACTCTGGGA TCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTACCTTCTGTACA GAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGAATCTACTTTG CTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAATCAAGATAACT GTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCATTCTGGAAAC TCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGAGTATGGGTTA CCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAACAAGCCCGAC CAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGGGGAAAATGTA TACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTATAGGCTCTCGG TGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACAGCCACGTCCA TCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAACTTCGAACTCC CAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGCTTCTACATAG CATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGACCCAGGTGGCT GTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTGCCCTGGATCA TGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAGCCTATGGGCA AACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTGGCCCCTCTGT TGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAGAAAGCCCAAG ACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACGTCGGACATGA TCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATCAACAACACTC TCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGCAGGTATCGTG ATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCTTTTATCATTG TCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCATTCCAGCAAC AACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAGAGAGCCACTG >4901_4901_9_ANO6-IAPP_ANO6_chr12_45816844_ENST00000441606_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=898AA_BP=829 MFCCGMFCAAVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNL ICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMND FYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQP LDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIF DSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWI LLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMK MFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSE KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAI LAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH -------------------------------------------------------------- >4901_4901_10_ANO6-IAPP_ANO6_chr12_45816844_ENST00000441606_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4450nt_BP=2708nt TTGGGGCAGAGGAGGCTTGTAGGAATAGGGGAAGAGTTCATAAGCAGAGCTGAAACAACACCAAACATGGAAATGTTACAAGGTGGAGAA ATTGTGCTTACTGAAACTCTTCTCAGAAATATTGCTGTTTGTGGATGATAGAAATCTTCAGAGTTGTCACTTAAGGTAGAGGTAGGAGGG TAAGAAGCGTCAAGGACTCACCGAATTGTCCATTCCCCCTTTTGTTCTGCTGTGGAATGTTTTGTGCTGCTGTGTTGGAAAACCTTGGAC AGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAACCTGACTCCC TCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAGGGTACAAATG AAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTATTGGATGACA AGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTGAAACCCAATG ATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAGCCAGAGCAAG AGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCCACCAGAAGCC GCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTAAACTCTGGGA TCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTACCTTCTGTACA GAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGAATCTACTTTG CTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAATCAAGATAACT GTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCATTCTGGAAAC TCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGAGTATGGGTTA CCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAACAAGCCCGAC CAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGGGGAAAATGTA TACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTATAGGCTCTCGG TGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACAGCCACGTCCA TCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAACTTCGAACTCC CAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGCTTCTACATAG CATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGACCCAGGTGGCT GTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTGCCCTGGATCA TGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAGCCTATGGGCA AACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTGGCCCCTCTGT TGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAGAAAGCCCAAG ACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACGTCGGACATGA TCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATCAACAACACTC TCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGCAGGTATCGTG ATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCTTTTATCATTG TCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCATTCCAGCAAC AACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAGAGAGCCACTG AATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTATAATTTAACAGTGCCCTTTTC ATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTCAAAAGATTGTTTTATATGTAGTACTAAC TAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTATTTTAAAACATAAGAACGTCATTTTGGG ACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTAAATTGTAAACAGCTAATAATGAAGTTAT TCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCAC AAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGGGTGGTGACATGTG CCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCACCACTG CACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTGTAAGTACCCCTGATAAGCAAATTAGTAA TTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTGTTTTAAAAACAAAGAAATAAAATCCTGC TCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAGGCTATTTAAAAGTATAAAACTGCTTTGT ATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTTATTTTGTTTAAGTGGCTTTCAGCAAACC TCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAATTAAAAGACCACAGACTTCTGGAAACTC TTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGTATATGATACACTTTTTTTGATAGCAGCT GCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTTTCCCTGACTTTGAGTTAGGTAGCTTTGG AAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCAACTTGTACTTTTAAAAAAATAGAAAAAA TAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCCCTTTATGAAGTGTGCCTTAGGTTACCAA ATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGAAATATATTTATAATAAATTCTATGTCAT >4901_4901_10_ANO6-IAPP_ANO6_chr12_45816844_ENST00000441606_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=898AA_BP=829 MFCCGMFCAAVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNL ICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMND FYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQP LDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIF DSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWI LLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMK MFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSE KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAI LAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH -------------------------------------------------------------- >4901_4901_11_ANO6-IAPP_ANO6_chr12_45816845_ENST00000320560_IAPP_chr12_21531170_ENST00000539393_length(transcript)=2987nt_BP=2728nt GAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCC AAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTC GGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATAT CGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATT TAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGAC CAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAAC AAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAA ATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAG CATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTT CAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAA CAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAA TGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGA GAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGG ATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAG GCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGT ATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACA GCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTT TACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGAT CATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGAC TCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTAT GATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTA CTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGA AGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGA AGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTA CCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTC TTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCT GGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCAT AGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGA AGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCA TACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGC CAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATT TTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGG TTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTAT >4901_4901_11_ANO6-IAPP_ANO6_chr12_45816845_ENST00000320560_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_12_ANO6-IAPP_ANO6_chr12_45816845_ENST00000320560_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4470nt_BP=2728nt GAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCC AAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTC GGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATAT CGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATT TAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGAC CAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAAC AAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAA ATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAG CATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTT CAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAA CAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAA TGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGA GAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGG ATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAG GCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGT ATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACA GCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTT TACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGAT CATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGAC TCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTAT GATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTA CTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGA AGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGA AGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTA CCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTC TTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCT GGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCAT AGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGA AGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCA TACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGC CAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATT TTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGG TTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTAT AATTTAACAGTGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTCAAAAGATT GTTTTATATGTAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTATTTTAAAA CATAAGAACGTCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTAAATTGTAA ACAGCTAATAATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGA GGCCGAGGCAGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTA GCCGGGGGTGGTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAGGTTGCAGT GAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTGTAAGTACC CCTGATAAGCAAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTGTTTTAAAA ACAAAGAAATAAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAGGCTATTTA AAAGTATAAAACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTTATTTTGTT TAAGTGGCTTTCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAATTAAAAGA CCACAGACTTCTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGTATATGATA CACTTTTTTTGATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTTTCCCTGAC TTTGAGTTAGGTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCAACTTGTAC TTTTAAAAAAATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCCCTTTATGA AGTGTGCCTTAGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGAAATATATT >4901_4901_12_ANO6-IAPP_ANO6_chr12_45816845_ENST00000320560_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_13_ANO6-IAPP_ANO6_chr12_45816845_ENST00000320560_IAPP_chr12_21531171_ENST00000539393_length(transcript)=2987nt_BP=2728nt GAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCC AAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTC GGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATAT CGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATT TAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGAC CAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAAC AAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAA ATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAG CATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTT CAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAA CAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAA TGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGA GAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGG ATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAG GCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGT ATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACA GCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTT TACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGAT CATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGAC TCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTAT GATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTA CTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGA AGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGA AGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTA CCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTC TTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCT GGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCAT AGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGA AGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCA TACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGC CAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATT TTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGG TTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTAT >4901_4901_13_ANO6-IAPP_ANO6_chr12_45816845_ENST00000320560_IAPP_chr12_21531171_ENST00000539393_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_14_ANO6-IAPP_ANO6_chr12_45816845_ENST00000320560_IAPP_chr12_21531171_ENST00000542023_length(transcript)=4470nt_BP=2728nt GAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCC AAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTC GGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATAT CGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATT TAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGAC CAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAAC AAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAA ATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAG CATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTT CAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAA CAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAA TGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGA GAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGG ATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAG GCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGT ATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACA GCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTT TACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGAT CATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGAC TCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTAT GATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTA CTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGA AGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGA AGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTA CCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTC TTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCT GGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCAT AGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGA AGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCA TACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGC CAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATT TTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGG TTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTAT AATTTAACAGTGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTCAAAAGATT GTTTTATATGTAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTATTTTAAAA CATAAGAACGTCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTAAATTGTAA ACAGCTAATAATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGA GGCCGAGGCAGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTA GCCGGGGGTGGTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAGGTTGCAGT GAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTGTAAGTACC CCTGATAAGCAAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTGTTTTAAAA ACAAAGAAATAAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAGGCTATTTA AAAGTATAAAACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTTATTTTGTT TAAGTGGCTTTCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAATTAAAAGA CCACAGACTTCTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGTATATGATA CACTTTTTTTGATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTTTCCCTGAC TTTGAGTTAGGTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCAACTTGTAC TTTTAAAAAAATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCCCTTTATGA AGTGTGCCTTAGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGAAATATATT >4901_4901_14_ANO6-IAPP_ANO6_chr12_45816845_ENST00000320560_IAPP_chr12_21531171_ENST00000542023_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_15_ANO6-IAPP_ANO6_chr12_45816845_ENST00000423947_IAPP_chr12_21531170_ENST00000539393_length(transcript)=3085nt_BP=2826nt GGGCATGCTCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTC CCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTC TGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAA ATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGGTGATGTTCCTGCCTCCAGGAGGCCTTTTCTGACTCCTCATACTCACCTCCCA TCCAGCCTGGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTT GAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGA AAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTA GAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATG CACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTA GACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGAT GCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTT GGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGC TGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATAC TATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTT CTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAG TGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTC TTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTT GAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGC ATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTT ATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAA TACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTG GCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTC AACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATAC AGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAAC ATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAA CAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTT GTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTT AGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCC ATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTAC ACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTG GGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTG ATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCT GGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGC AGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATT >4901_4901_15_ANO6-IAPP_ANO6_chr12_45816845_ENST00000423947_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=972AA_BP=903 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIGDVPASRRPFLTPHTHLPSSLVLENLG QTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDD KLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRS RIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYF AWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWV TLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLS VFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYI AFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMG KLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDM IPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFII -------------------------------------------------------------- >4901_4901_16_ANO6-IAPP_ANO6_chr12_45816845_ENST00000423947_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4568nt_BP=2826nt GGGCATGCTCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTC CCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTC TGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAA ATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGGTGATGTTCCTGCCTCCAGGAGGCCTTTTCTGACTCCTCATACTCACCTCCCA TCCAGCCTGGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTT GAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGA AAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTA GAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATG CACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTA GACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGAT GCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTT GGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGC TGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATAC TATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTT CTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAG TGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTC TTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTT GAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGC ATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTT ATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAA TACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTG GCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTC AACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATAC AGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAAC ATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAA CAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTT GTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTT AGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCC ATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTAC ACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTG GGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTG ATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCT GGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGC AGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATT TCCTGTATAATTTAACAGTGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTC AAAAGATTGTTTTATATGTAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTA TTTTAAAACATAAGAACGTCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTA AATTGTAAACAGCTAATAATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCA CTTTGGGAGGCCGAGGCAGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATAC AAAAATTAGCCGGGGGTGGTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAG GTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTG TAAGTACCCCTGATAAGCAAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTG TTTTAAAAACAAAGAAATAAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAG GCTATTTAAAAGTATAAAACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTT ATTTTGTTTAAGTGGCTTTCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAA TTAAAAGACCACAGACTTCTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGT ATATGATACACTTTTTTTGATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTT TCCCTGACTTTGAGTTAGGTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCA ACTTGTACTTTTAAAAAAATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCC CTTTATGAAGTGTGCCTTAGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGA >4901_4901_16_ANO6-IAPP_ANO6_chr12_45816845_ENST00000423947_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=972AA_BP=903 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIGDVPASRRPFLTPHTHLPSSLVLENLG QTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDD KLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRS RIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYF AWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWV TLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLS VFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYI AFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMG KLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDM IPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFII -------------------------------------------------------------- >4901_4901_17_ANO6-IAPP_ANO6_chr12_45816845_ENST00000423947_IAPP_chr12_21531171_ENST00000539393_length(transcript)=3085nt_BP=2826nt GGGCATGCTCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTC CCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTC TGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAA ATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGGTGATGTTCCTGCCTCCAGGAGGCCTTTTCTGACTCCTCATACTCACCTCCCA TCCAGCCTGGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTT GAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGA AAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTA GAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATG CACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTA GACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGAT GCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTT GGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGC TGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATAC TATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTT CTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAG TGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTC TTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTT GAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGC ATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTT ATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAA TACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTG GCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTC AACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATAC AGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAAC ATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAA CAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTT GTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTT AGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCC ATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTAC ACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTG GGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTG ATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCT GGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGC AGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATT >4901_4901_17_ANO6-IAPP_ANO6_chr12_45816845_ENST00000423947_IAPP_chr12_21531171_ENST00000539393_length(amino acids)=972AA_BP=903 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIGDVPASRRPFLTPHTHLPSSLVLENLG QTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDD KLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRS RIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYF AWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWV TLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLS VFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYI AFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMG KLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDM IPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFII -------------------------------------------------------------- >4901_4901_18_ANO6-IAPP_ANO6_chr12_45816845_ENST00000423947_IAPP_chr12_21531171_ENST00000542023_length(transcript)=4568nt_BP=2826nt GGGCATGCTCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTC CCCGGCGCTGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTC TGGAACCCGGGAGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAA ATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGGTGATGTTCCTGCCTCCAGGAGGCCTTTTCTGACTCCTCATACTCACCTCCCA TCCAGCCTGGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTT GAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGA AAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTA GAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATG CACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTA GACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGAT GCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTT GGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGC TGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATAC TATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTT CTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAG TGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTC TTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTT GAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGC ATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTT ATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAA TACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTG GCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTC AACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATAC AGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAAC ATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAA CAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTT GTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTT AGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCC ATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTAC ACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTG GGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTG ATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCT GGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGC AGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATT TCCTGTATAATTTAACAGTGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTC AAAAGATTGTTTTATATGTAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTA TTTTAAAACATAAGAACGTCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTA AATTGTAAACAGCTAATAATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCA CTTTGGGAGGCCGAGGCAGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATAC AAAAATTAGCCGGGGGTGGTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAG GTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTG TAAGTACCCCTGATAAGCAAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTG TTTTAAAAACAAAGAAATAAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAG GCTATTTAAAAGTATAAAACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTT ATTTTGTTTAAGTGGCTTTCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAA TTAAAAGACCACAGACTTCTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGT ATATGATACACTTTTTTTGATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTT TCCCTGACTTTGAGTTAGGTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCA ACTTGTACTTTTAAAAAAATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCC CTTTATGAAGTGTGCCTTAGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGA >4901_4901_18_ANO6-IAPP_ANO6_chr12_45816845_ENST00000423947_IAPP_chr12_21531171_ENST00000542023_length(amino acids)=972AA_BP=903 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIGDVPASRRPFLTPHTHLPSSLVLENLG QTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDD KLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRS RIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYF AWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWV TLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLS VFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYI AFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMG KLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDM IPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFII -------------------------------------------------------------- >4901_4901_19_ANO6-IAPP_ANO6_chr12_45816845_ENST00000425752_IAPP_chr12_21531170_ENST00000539393_length(transcript)=3087nt_BP=2828nt CTTCTGCGCGCCTCGTAAAACCGGGGAAGTTCAATCATTCCGCAGCGAGCCGCGGCGGCCGCACTGGGCATGCTCAGTCTCCGGGCTCCG CTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGC CCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCG CGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACG ATGGGGATATCGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGT TTGAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCA GAAAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGT TAGAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAA TGCACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTG TAGACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAG ATGCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGT TTGGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCA GCTGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAAT ACTATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCT TTCTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTC AGTGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGG TCTTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTG TTGAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAAC GCATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAG TTATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGA AATACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAG TGGCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTG TCAACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAAT ACAGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATA ACATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGG AACAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTAT TTGTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGT TTAGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATG CCATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCT ACACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACC TGGGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATG TGATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGC CTGGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAAT GCAGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGA >4901_4901_19_ANO6-IAPP_ANO6_chr12_45816845_ENST00000425752_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_20_ANO6-IAPP_ANO6_chr12_45816845_ENST00000425752_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4570nt_BP=2828nt CTTCTGCGCGCCTCGTAAAACCGGGGAAGTTCAATCATTCCGCAGCGAGCCGCGGCGGCCGCACTGGGCATGCTCAGTCTCCGGGCTCCG CTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGC CCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCG CGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACG ATGGGGATATCGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGT TTGAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCA GAAAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGT TAGAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAA TGCACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTG TAGACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAG ATGCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGT TTGGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCA GCTGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAAT ACTATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCT TTCTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTC AGTGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGG TCTTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTG TTGAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAAC GCATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAG TTATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGA AATACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAG TGGCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTG TCAACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAAT ACAGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATA ACATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGG AACAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTAT TTGTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGT TTAGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATG CCATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCT ACACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACC TGGGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATG TGATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGC CTGGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAAT GCAGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGA TTTCCTGTATAATTTAACAGTGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTC TCAAAAGATTGTTTTATATGTAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTG TATTTTAAAACATAAGAACGTCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGG TAAATTGTAAACAGCTAATAATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAG CACTTTGGGAGGCCGAGGCAGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAAT ACAAAAATTAGCCGGGGGTGGTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGG AGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAAT TGTAAGTACCCCTGATAAGCAAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGC TGTTTTAAAAACAAAGAAATAAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAG AGGCTATTTAAAAGTATAAAACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCAT TTATTTTGTTTAAGTGGCTTTCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTC AATTAAAAGACCACAGACTTCTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTAT GTATATGATACACTTTTTTTGATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCT TTTCCCTGACTTTGAGTTAGGTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACT CAACTTGTACTTTTAAAAAAATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTT CCCTTTATGAAGTGTGCCTTAGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGG >4901_4901_20_ANO6-IAPP_ANO6_chr12_45816845_ENST00000425752_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_21_ANO6-IAPP_ANO6_chr12_45816845_ENST00000425752_IAPP_chr12_21531171_ENST00000539393_length(transcript)=3087nt_BP=2828nt CTTCTGCGCGCCTCGTAAAACCGGGGAAGTTCAATCATTCCGCAGCGAGCCGCGGCGGCCGCACTGGGCATGCTCAGTCTCCGGGCTCCG CTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGC CCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCG CGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACG ATGGGGATATCGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGT TTGAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCA GAAAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGT TAGAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAA TGCACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTG TAGACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAG ATGCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGT TTGGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCA GCTGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAAT ACTATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCT TTCTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTC AGTGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGG TCTTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTG TTGAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAAC GCATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAG TTATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGA AATACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAG TGGCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTG TCAACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAAT ACAGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATA ACATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGG AACAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTAT TTGTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGT TTAGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATG CCATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCT ACACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACC TGGGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATG TGATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGC CTGGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAAT GCAGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGA >4901_4901_21_ANO6-IAPP_ANO6_chr12_45816845_ENST00000425752_IAPP_chr12_21531171_ENST00000539393_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_22_ANO6-IAPP_ANO6_chr12_45816845_ENST00000425752_IAPP_chr12_21531171_ENST00000542023_length(transcript)=4570nt_BP=2828nt CTTCTGCGCGCCTCGTAAAACCGGGGAAGTTCAATCATTCCGCAGCGAGCCGCGGCGGCCGCACTGGGCATGCTCAGTCTCCGGGCTCCG CTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGCTGGCTGGGCTCAGCGGC CCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGGCCCCTGGGAGAGCCGCGCCGTTCTGGAACCCGGGAGCCCCCAACTTCG CGCCAAGTTCGGAGCCGCCTTCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACG ATGGGGATATCGTGTTGGAAAACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGT TTGAAGAATTTAATGGAAAACCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCA GAAAAGAGACCAATAAAAAGGGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGT TAGAAGCAACAAGATCAGTATTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAA TGCACATCAAATTGCCTCTGAAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTG TAGACGAAAGCATCATCAAGCCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAG ATGCTTTCTTCAATCCAGCCACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGT TTGGGATCAACAGACTTGTAAACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCA GCTGCCCTAATGAACGGTACCTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAAT ACTATGGAGAGAAGATTGGAATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCT TTCTCTATGGATATCTTAATCAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTC AGTGTGATAGGCTTTGTCCATTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGG TCTTTGCAGTATTTATGGGAGTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTG TTGAGTTACAGCAGGAAGAACAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAAC GCATTCCCTTTACTGCCTGGGGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAG TTATTGGGATCATTGTCTATAGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGA AATACCTGACTCCACAGACAGCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAG TGGCAATTATGATTACTAACTTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTG TCAACTACTACTCTTCATGCTTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAAT ACAGAAATGAAGAGTGTGACCCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATA ACATACAAGAAGTATTATTGCCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGG AACAGGACTACCATCTGCAGCCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTAT TTGTGGCCTCTTTTCCACTGGCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGT TTAGACGCCTGGTACCAGAGAAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATG CCATGATCATAGCTTTCACGTCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCT ACACCATGGAAGGGTACATCAACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACC TGGGTAACCATACCACATGCAGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATG TGATTGCAGCCAAGCTGGCTTTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGC CTGGCAAATTTTTTAGTTCATTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAAT GCAGTAGAGGTTTTAAAGAGAGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGA TTTCCTGTATAATTTAACAGTGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTC TCAAAAGATTGTTTTATATGTAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTG TATTTTAAAACATAAGAACGTCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGG TAAATTGTAAACAGCTAATAATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAG CACTTTGGGAGGCCGAGGCAGGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAAT ACAAAAATTAGCCGGGGGTGGTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGG AGGTTGCAGTGAGCCGAGATTGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAAT TGTAAGTACCCCTGATAAGCAAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGC TGTTTTAAAAACAAAGAAATAAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAG AGGCTATTTAAAAGTATAAAACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCAT TTATTTTGTTTAAGTGGCTTTCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTC AATTAAAAGACCACAGACTTCTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTAT GTATATGATACACTTTTTTTGATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCT TTTCCCTGACTTTGAGTTAGGTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACT CAACTTGTACTTTTAAAAAAATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTT CCCTTTATGAAGTGTGCCTTAGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGG >4901_4901_22_ANO6-IAPP_ANO6_chr12_45816845_ENST00000425752_IAPP_chr12_21531171_ENST00000542023_length(amino acids)=951AA_BP=882 MSPSDTRPAVPDPAPGRAAPFWNPGAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLESQHDFRTPEF EEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIM HIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKF GINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACF LYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTV ELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQK YLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKY RNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLF VASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSY TMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQHCHMCNAAP -------------------------------------------------------------- >4901_4901_23_ANO6-IAPP_ANO6_chr12_45816845_ENST00000435642_IAPP_chr12_21531170_ENST00000539393_length(transcript)=2977nt_BP=2718nt TCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGC TGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCT TCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGTGTTGGAA AACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAA CCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAG GGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTA TTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTG AAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAG CCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCC ACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTA AACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTAC CTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGA ATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAAT CAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCA TTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGA GTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAA CAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGG GGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTAT AGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACA GCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAAC TTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGC TTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGAC CCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTG CCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAG CCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTG GCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAG AAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACG TCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATC AACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGC AGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCT TTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCA TTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAG AGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTATAATTTAACAG >4901_4901_23_ANO6-IAPP_ANO6_chr12_45816845_ENST00000435642_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=960AA_BP=891 MGSGRWVPRLGFPRRWLGSAAPEPKRHTPRGPRSAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLES QHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWE VLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKY QVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLL AAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQA ELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKN INGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPG DPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMI IQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSV PPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQ -------------------------------------------------------------- >4901_4901_24_ANO6-IAPP_ANO6_chr12_45816845_ENST00000435642_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4460nt_BP=2718nt TCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGC TGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCT TCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGTGTTGGAA AACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAA CCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAG GGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTA TTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTG AAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAG CCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCC ACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTA AACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTAC CTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGA ATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAAT CAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCA TTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGA GTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAA CAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGG GGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTAT AGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACA GCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAAC TTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGC TTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGAC CCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTG CCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAG CCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTG GCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAG AAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACG TCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATC AACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGC AGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCT TTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCA TTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAG AGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTATAATTTAACAG TGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTCAAAAGATTGTTTTATATG TAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTATTTTAAAACATAAGAACG TCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTAAATTGTAAACAGCTAATA ATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCA GGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGGGTG GTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGAT TGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTGTAAGTACCCCTGATAAGC AAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTGTTTTAAAAACAAAGAAAT AAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAGGCTATTTAAAAGTATAAA ACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTTATTTTGTTTAAGTGGCTT TCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAATTAAAAGACCACAGACTT CTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGTATATGATACACTTTTTTT GATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTTTCCCTGACTTTGAGTTAG GTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCAACTTGTACTTTTAAAAAA ATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCCCTTTATGAAGTGTGCCTT AGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGAAATATATTTATAATAAAT >4901_4901_24_ANO6-IAPP_ANO6_chr12_45816845_ENST00000435642_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=960AA_BP=891 MGSGRWVPRLGFPRRWLGSAAPEPKRHTPRGPRSAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLES QHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWE VLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKY QVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLL AAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQA ELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKN INGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPG DPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMI IQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSV PPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQ -------------------------------------------------------------- >4901_4901_25_ANO6-IAPP_ANO6_chr12_45816845_ENST00000435642_IAPP_chr12_21531171_ENST00000539393_length(transcript)=2977nt_BP=2718nt TCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGC TGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCT TCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGTGTTGGAA AACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAA CCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAG GGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTA TTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTG AAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAG CCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCC ACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTA AACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTAC CTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGA ATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAAT CAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCA TTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGA GTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAA CAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGG GGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTAT AGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACA GCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAAC TTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGC TTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGAC CCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTG CCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAG CCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTG GCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAG AAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACG TCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATC AACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGC AGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCT TTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCA TTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAG AGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTATAATTTAACAG >4901_4901_25_ANO6-IAPP_ANO6_chr12_45816845_ENST00000435642_IAPP_chr12_21531171_ENST00000539393_length(amino acids)=960AA_BP=891 MGSGRWVPRLGFPRRWLGSAAPEPKRHTPRGPRSAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLES QHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWE VLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKY QVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLL AAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQA ELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKN INGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPG DPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMI IQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSV PPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQ -------------------------------------------------------------- >4901_4901_26_ANO6-IAPP_ANO6_chr12_45816845_ENST00000435642_IAPP_chr12_21531171_ENST00000542023_length(transcript)=4460nt_BP=2718nt TCAGTCTCCGGGCTCCGCTCGGCAGGCGAGAGGCGTCCTCCGGCTCTGGGCTCCGGTCGGTGGGTGCCTCGGCTCGGCTTTCCCCGGCGC TGGCTGGGCTCAGCGGCCCCTGAGCCCAAGCGACACACGCCCCGCGGTCCCCGATCCGCCCCCAACTTCGCGCCAAGTTCGGAGCCGCCT TCTGAGGGAGACATGAAAAAGATGAGCAGGAATGTTTTGCTACAAATGGAGGAGGAGGAGGACGACGACGATGGGGATATCGTGTTGGAA AACCTTGGACAGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAA CCTGACTCCCTCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAG GGTACAAATGAAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTA TTGGATGACAAGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTG AAACCCAATGATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAG CCAGAGCAAGAGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCC ACCAGAAGCCGCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTA AACTCTGGGATCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTAC CTTCTGTACAGAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGA ATCTACTTTGCTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAAT CAAGATAACTGTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCA TTCTGGAAACTCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGA GTATGGGTTACCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAA CAAGCCCGACCAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGG GGAAAATGTATACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTAT AGGCTCTCGGTGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACA GCCACGTCCATCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAAC TTCGAACTCCCAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGC TTCTACATAGCATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGAC CCAGGTGGCTGTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTG CCCTGGATCATGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAG CCTATGGGCAAACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTG GCCCCTCTGTTGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAG AAAGCCCAAGACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACG TCGGACATGATCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATC AACAACACTCTCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGC AGGTATCGTGATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCT TTTATCATTGTCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCA TTCCAGCAACAACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAG AGAGCCACTGAATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTATAATTTAACAG TGCCCTTTTCATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTCAAAAGATTGTTTTATATG TAGTACTAACTAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTATTTTAAAACATAAGAACG TCATTTTGGGACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTAAATTGTAAACAGCTAATA ATGAAGTTATTCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCA GGCAGATCACAAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGGGTG GTGACATGTGCCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGAT TGCACCACTGCACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTGTAAGTACCCCTGATAAGC AAATTAGTAATTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTGTTTTAAAAACAAAGAAAT AAAATCCTGCTCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAGGCTATTTAAAAGTATAAA ACTGCTTTGTATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTTATTTTGTTTAAGTGGCTT TCAGCAAACCTCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAATTAAAAGACCACAGACTT CTGGAAACTCTTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGTATATGATACACTTTTTTT GATAGCAGCTGCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTTTCCCTGACTTTGAGTTAG GTAGCTTTGGAAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCAACTTGTACTTTTAAAAAA ATAGAAAAAATAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCCCTTTATGAAGTGTGCCTT AGGTTACCAAATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGAAATATATTTATAATAAAT >4901_4901_26_ANO6-IAPP_ANO6_chr12_45816845_ENST00000435642_IAPP_chr12_21531171_ENST00000542023_length(amino acids)=960AA_BP=891 MGSGRWVPRLGFPRRWLGSAAPEPKRHTPRGPRSAPNFAPSSEPPSEGDMKKMSRNVLLQMEEEEDDDDGDIVLENLGQTIVPDLGSLES QHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNLICHGLQLEATRSVLDDKLVFVKVHAPWE VLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMNDFYIVDRDAFFNPATRSRIVYFILSRVKY QVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQPLDLIRKYYGEKIGIYFAWLGYYTQMLLL AAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIFDSFGTLVFAVFMGVWVTLFLEFWKRRQA ELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWILLIIASVIGIIVYRLSVFIVFSAKLPKN INGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMKMFLFQFVNYYSSCFYIAFFKGKFVGYPG DPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSEKITPRWEQDYHLQPMGKLGLFYEYLEMI IQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAILAVVTNAMIIAFTSDMIPRLVYYWSFSV PPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKHNIYYWHVIAAKLAFIIVMESSGGKAEMQ -------------------------------------------------------------- >4901_4901_27_ANO6-IAPP_ANO6_chr12_45816845_ENST00000441606_IAPP_chr12_21531170_ENST00000539393_length(transcript)=2967nt_BP=2708nt TTGGGGCAGAGGAGGCTTGTAGGAATAGGGGAAGAGTTCATAAGCAGAGCTGAAACAACACCAAACATGGAAATGTTACAAGGTGGAGAA ATTGTGCTTACTGAAACTCTTCTCAGAAATATTGCTGTTTGTGGATGATAGAAATCTTCAGAGTTGTCACTTAAGGTAGAGGTAGGAGGG TAAGAAGCGTCAAGGACTCACCGAATTGTCCATTCCCCCTTTTGTTCTGCTGTGGAATGTTTTGTGCTGCTGTGTTGGAAAACCTTGGAC AGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAACCTGACTCCC TCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAGGGTACAAATG AAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTATTGGATGACA AGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTGAAACCCAATG ATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAGCCAGAGCAAG AGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCCACCAGAAGCC GCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTAAACTCTGGGA TCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTACCTTCTGTACA GAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGAATCTACTTTG CTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAATCAAGATAACT GTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCATTCTGGAAAC TCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGAGTATGGGTTA CCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAACAAGCCCGAC CAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGGGGAAAATGTA TACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTATAGGCTCTCGG TGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACAGCCACGTCCA TCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAACTTCGAACTCC CAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGCTTCTACATAG CATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGACCCAGGTGGCT GTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTGCCCTGGATCA TGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAGCCTATGGGCA AACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTGGCCCCTCTGT TGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAGAAAGCCCAAG ACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACGTCGGACATGA TCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATCAACAACACTC TCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGCAGGTATCGTG ATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCTTTTATCATTG TCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCATTCCAGCAAC AACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAGAGAGCCACTG >4901_4901_27_ANO6-IAPP_ANO6_chr12_45816845_ENST00000441606_IAPP_chr12_21531170_ENST00000539393_length(amino acids)=898AA_BP=829 MFCCGMFCAAVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNL ICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMND FYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQP LDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIF DSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWI LLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMK MFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSE KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAI LAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH -------------------------------------------------------------- >4901_4901_28_ANO6-IAPP_ANO6_chr12_45816845_ENST00000441606_IAPP_chr12_21531170_ENST00000542023_length(transcript)=4450nt_BP=2708nt TTGGGGCAGAGGAGGCTTGTAGGAATAGGGGAAGAGTTCATAAGCAGAGCTGAAACAACACCAAACATGGAAATGTTACAAGGTGGAGAA ATTGTGCTTACTGAAACTCTTCTCAGAAATATTGCTGTTTGTGGATGATAGAAATCTTCAGAGTTGTCACTTAAGGTAGAGGTAGGAGGG TAAGAAGCGTCAAGGACTCACCGAATTGTCCATTCCCCCTTTTGTTCTGCTGTGGAATGTTTTGTGCTGCTGTGTTGGAAAACCTTGGAC AGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAACCTGACTCCC TCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAGGGTACAAATG AAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTATTGGATGACA AGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTGAAACCCAATG ATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAGCCAGAGCAAG AGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCCACCAGAAGCC GCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTAAACTCTGGGA TCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTACCTTCTGTACA GAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGAATCTACTTTG CTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAATCAAGATAACT GTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCATTCTGGAAAC TCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGAGTATGGGTTA CCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAACAAGCCCGAC CAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGGGGAAAATGTA TACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTATAGGCTCTCGG TGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACAGCCACGTCCA TCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAACTTCGAACTCC CAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGCTTCTACATAG CATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGACCCAGGTGGCT GTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTGCCCTGGATCA TGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAGCCTATGGGCA AACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTGGCCCCTCTGT TGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAGAAAGCCCAAG ACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACGTCGGACATGA TCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATCAACAACACTC TCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGCAGGTATCGTG ATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCTTTTATCATTG TCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCATTCCAGCAAC AACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAGAGAGCCACTG AATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTATAATTTAACAGTGCCCTTTTC ATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTCAAAAGATTGTTTTATATGTAGTACTAAC TAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTATTTTAAAACATAAGAACGTCATTTTGGG ACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTAAATTGTAAACAGCTAATAATGAAGTTAT TCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCAC AAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGGGTGGTGACATGTG CCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCACCACTG CACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTGTAAGTACCCCTGATAAGCAAATTAGTAA TTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTGTTTTAAAAACAAAGAAATAAAATCCTGC TCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAGGCTATTTAAAAGTATAAAACTGCTTTGT ATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTTATTTTGTTTAAGTGGCTTTCAGCAAACC TCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAATTAAAAGACCACAGACTTCTGGAAACTC TTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGTATATGATACACTTTTTTTGATAGCAGCT GCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTTTCCCTGACTTTGAGTTAGGTAGCTTTGG AAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCAACTTGTACTTTTAAAAAAATAGAAAAAA TAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCCCTTTATGAAGTGTGCCTTAGGTTACCAA ATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGAAATATATTTATAATAAATTCTATGTCAT >4901_4901_28_ANO6-IAPP_ANO6_chr12_45816845_ENST00000441606_IAPP_chr12_21531170_ENST00000542023_length(amino acids)=898AA_BP=829 MFCCGMFCAAVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNL ICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMND FYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQP LDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIF DSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWI LLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMK MFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSE KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAI LAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH -------------------------------------------------------------- >4901_4901_29_ANO6-IAPP_ANO6_chr12_45816845_ENST00000441606_IAPP_chr12_21531171_ENST00000539393_length(transcript)=2967nt_BP=2708nt TTGGGGCAGAGGAGGCTTGTAGGAATAGGGGAAGAGTTCATAAGCAGAGCTGAAACAACACCAAACATGGAAATGTTACAAGGTGGAGAA ATTGTGCTTACTGAAACTCTTCTCAGAAATATTGCTGTTTGTGGATGATAGAAATCTTCAGAGTTGTCACTTAAGGTAGAGGTAGGAGGG TAAGAAGCGTCAAGGACTCACCGAATTGTCCATTCCCCCTTTTGTTCTGCTGTGGAATGTTTTGTGCTGCTGTGTTGGAAAACCTTGGAC AGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAACCTGACTCCC TCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAGGGTACAAATG AAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTATTGGATGACA AGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTGAAACCCAATG ATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAGCCAGAGCAAG AGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCCACCAGAAGCC GCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTAAACTCTGGGA TCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTACCTTCTGTACA GAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGAATCTACTTTG CTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAATCAAGATAACT GTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCATTCTGGAAAC TCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGAGTATGGGTTA CCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAACAAGCCCGAC CAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGGGGAAAATGTA TACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTATAGGCTCTCGG TGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACAGCCACGTCCA TCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAACTTCGAACTCC CAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGCTTCTACATAG CATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGACCCAGGTGGCT GTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTGCCCTGGATCA TGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAGCCTATGGGCA AACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTGGCCCCTCTGT TGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAGAAAGCCCAAG ACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACGTCGGACATGA TCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATCAACAACACTC TCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGCAGGTATCGTG ATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCTTTTATCATTG TCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCATTCCAGCAAC AACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAGAGAGCCACTG >4901_4901_29_ANO6-IAPP_ANO6_chr12_45816845_ENST00000441606_IAPP_chr12_21531171_ENST00000539393_length(amino acids)=898AA_BP=829 MFCCGMFCAAVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNL ICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMND FYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQP LDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIF DSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWI LLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMK MFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSE KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAI LAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH -------------------------------------------------------------- >4901_4901_30_ANO6-IAPP_ANO6_chr12_45816845_ENST00000441606_IAPP_chr12_21531171_ENST00000542023_length(transcript)=4450nt_BP=2708nt TTGGGGCAGAGGAGGCTTGTAGGAATAGGGGAAGAGTTCATAAGCAGAGCTGAAACAACACCAAACATGGAAATGTTACAAGGTGGAGAA ATTGTGCTTACTGAAACTCTTCTCAGAAATATTGCTGTTTGTGGATGATAGAAATCTTCAGAGTTGTCACTTAAGGTAGAGGTAGGAGGG TAAGAAGCGTCAAGGACTCACCGAATTGTCCATTCCCCCTTTTGTTCTGCTGTGGAATGTTTTGTGCTGCTGTGTTGGAAAACCTTGGAC AGACAATTGTCCCCGATTTGGGATCACTGGAAAGTCAGCATGATTTTCGAACCCCGGAGTTTGAAGAATTTAATGGAAAACCTGACTCCC TCTTTTTTAATGATGGCCAGCGAAGAATTGACTTTGTTCTAGTATATGAGGATGAAAGCAGAAAAGAGACCAATAAAAAGGGTACAAATG AAAAACAAAGGAGGAAAAGACAAGCATACGAATCTAACCTTATCTGTCATGGCCTGCAGTTAGAAGCAACAAGATCAGTATTGGATGACA AGCTTGTATTTGTAAAAGTACACGCACCATGGGAGGTGTTATGTACGTATGCTGAGATAATGCACATCAAATTGCCTCTGAAACCCAATG ATCTGAAAAACCGGTCCTCAGCCTTTGGTACACTCAACTGGTTTACCAAAGTCCTCAGTGTAGACGAAAGCATCATCAAGCCAGAGCAAG AGTTTTTCACTGCCCCATTTGAGAAGAACCGGATGAATGATTTTTACATAGTTGATAGAGATGCTTTCTTCAATCCAGCCACCAGAAGCC GCATTGTTTACTTCATCCTCTCTCGGGTCAAGTATCAAGTGATAAACAATGTTAGCAAGTTTGGGATCAACAGACTTGTAAACTCTGGGA TCTACAAGGCAGCTTTCCCACTCCATGATTGCAAATTCCGCCGTCAGTCAGAGGATCCCAGCTGCCCTAATGAACGGTACCTTCTGTACA GAGAATGGGCTCATCCTCGAAGCATATACAAAAAGCAGCCCTTGGATCTTATCAGGAAATACTATGGAGAGAAGATTGGAATCTACTTTG CTTGGCTGGGCTATTACACTCAGATGCTTCTCCTGGCCGCAGTTGTAGGAGTGGCTTGCTTTCTCTATGGATATCTTAATCAAGATAACT GTACATGGAGCAAAGAAGTTTGTCATCCTGATATTGGTGGCAAGATCATAATGTGTCCTCAGTGTGATAGGCTTTGTCCATTCTGGAAAC TCAATATTACTTGCGAGTCCTCAAAGAAATTGTGCATCTTCGACAGTTTTGGAACCCTGGTCTTTGCAGTATTTATGGGAGTATGGGTTA CCTTGTTTTTGGAGTTTTGGAAGCGACGCCAGGCAGAACTTGAGTATGAATGGGATACTGTTGAGTTACAGCAGGAAGAACAAGCCCGAC CAGAATACGAAGCACGATGTACTCACGTAGTGATAAATGAGATTACTCAGGAAGAAGAACGCATTCCCTTTACTGCCTGGGGAAAATGTA TACGGATAACCCTCTGTGCCAGTGCTGTCTTTTTCTGGATCCTATTGATCATCGCTTCAGTTATTGGGATCATTGTCTATAGGCTCTCGG TGTTCATTGTATTTTCTGCAAAACTTCCCAAGAACATTAATGGAACAGACCCAATCCAGAAATACCTGACTCCACAGACAGCCACGTCCA TCACGGCCTCCATCATCAGCTTTATAATTATCATGATTCTGAACACCATATATGAAAAAGTGGCAATTATGATTACTAACTTCGAACTCC CAAGGACCCAGACTGATTATGAGAACAGCCTCACCATGAAGATGTTCTTATTCCAGTTTGTCAACTACTACTCTTCATGCTTCTACATAG CATTCTTTAAGGGCAAATTTGTAGGCTATCCAGGAGACCCAGTTTATTGGTTGGGAAAATACAGAAATGAAGAGTGTGACCCAGGTGGCT GTCTTCTTGAACTGACAACTCAGCTGACAATAATCATGGGAGGAAAAGCAATCTGGAATAACATACAAGAAGTATTATTGCCCTGGATCA TGAATCTAATTGGGCGATTTCACAGAGTTTCTGGATCAGAAAAGATAACCCCACGATGGGAACAGGACTACCATCTGCAGCCTATGGGCA AACTGGGATTATTTTATGAATATCTTGAAATGATTATTCAGTTTGGGTTCGTCACCTTATTTGTGGCCTCTTTTCCACTGGCCCCTCTGT TGGCTCTCGTGAACAATATATTGGAAATAAGAGTGGACGCATGGAAACTGACCACCCAGTTTAGACGCCTGGTACCAGAGAAAGCCCAAG ACATTGGAGCATGGCAGCCCATCATGCAAGGAATAGCAATTCTGGCTGTGGTGACCAATGCCATGATCATAGCTTTCACGTCGGACATGA TCCCCCGCCTAGTGTACTACTGGTCCTTCTCCGTCCCTCCCTACGGGGACCACACTTCCTACACCATGGAAGGGTACATCAACAACACTC TCTCCATCTTCAAAGTCGCAGACTTCAAAAACAAAAGCAAGGGAAACCCGTACTCTGACCTGGGTAACCATACCACATGCAGGTATCGTG ATTTCCGATACCCACCTGGACACCCCCAGGAGTATAAACACAACATCTACTATTGGCATGTGATTGCAGCCAAGCTGGCTTTTATCATTG TCATGGAGTCATCAGGTGGAAAAGCGGAAATGCAACACTGCCACATGTGCAACGCAGCGCCTGGCAAATTTTTTAGTTCATTCCAGCAAC AACTTTGGTGCCATTCTCTCATCTACCAACGTGGGATCCAATACATATGGCAAGAGGAATGCAGTAGAGGTTTTAAAGAGAGAGCCACTG AATTACTTGCCCCTTTAGAGGACAATGTAACTCTATAGTTATTGTTTTATGTTCTAGTGATTTCCTGTATAATTTAACAGTGCCCTTTTC ATCTCCAGTGTGAATATATGGTCTGTGTGTCTGATGTTTGTTGCTAGGACATATACCTTCTCAAAAGATTGTTTTATATGTAGTACTAAC TAAGGTCCCATAATAAAAAGATAGTATCTTTTAAAATGAAATGTTTTTGCTATAGATTTGTATTTTAAAACATAAGAACGTCATTTTGGG ACCTATATCTCAGTGGCACAGGTTTAAGAACGAAGGAGAAAAAGGTAGTTTGAACCTTGGTAAATTGTAAACAGCTAATAATGAAGTTAT TCTTGACATGAGAAAATCAGTAATTGGACCAGGCGCGGTGGCTCTTGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCAC AAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCCGGGGGTGGTGACATGTG CCTGTAATCCCAGCTACTCAGGAGGCTAAGGCAGGAGAATCGCTTAAACCCAGGAGGCGGAGGTTGCAGTGAGCCGAGATTGCACCACTG CACTCCAGCCTGGGTGGCAGAGTGAGACTCGTCTCAAAAAAAAGAAAGAAAATTAGTAATTGTAAGTACCCCTGATAAGCAAATTAGTAA TTGTCAATACCCCTGTTAAGCAATTCCTTTTTGCAGTATATTTCTGAAATGACAGAATGCTGTTTTAAAAACAAAGAAATAAAATCCTGC TCCTGACTCGGTCAAAATATTTTTTAAAGTCTATTGTTTGTTGTGCTTGCTGGTACTAAGAGGCTATTTAAAAGTATAAAACTGCTTTGT ATCCATGAGGGTTTCATTGTGTGTTAGCAGCAGTGAGCTTCTATTAAATGTATATGTCATTTATTTTGTTTAAGTGGCTTTCAGCAAACC TCAGTCATATTCTTATGCAGGGTATTGCGAAACAACTTGTGTTCTATTAATCGTGTCTTCAATTAAAAGACCACAGACTTCTGGAAACTC TTTGCTGTATAAGAATTATTTCTTTTGTTTAACAAATTAGACATTTCTGGCAGAGGTTATGTATATGATACACTTTTTTTGATAGCAGCT GCAATGTTGGACAGAAGATGAAATGCTTTGCTTTGAGTCAGATTCTTATGAATATCTGCTTTTCCCTGACTTTGAGTTAGGTAGCTTTGG AAGTAGCATTAATTCAGATAAACTGCCATCATGCTGCGTTATGCCATTTCTAAAGACACTCAACTTGTACTTTTAAAAAAATAGAAAAAA TAAGCATTTCAATCTAAGTGGAAATTTGACTCATTGACTTACATTTCTAAGTTAAAATTTCCCTTTATGAAGTGTGCCTTAGGTTACCAA ATTGTAGAGGCTTTCGTTGGTGGTGGTAAGTGGTAGCGGTAGTGAGTGTATAGAGGCAGGGAAATATATTTATAATAAATTCTATGTCAT >4901_4901_30_ANO6-IAPP_ANO6_chr12_45816845_ENST00000441606_IAPP_chr12_21531171_ENST00000542023_length(amino acids)=898AA_BP=829 MFCCGMFCAAVLENLGQTIVPDLGSLESQHDFRTPEFEEFNGKPDSLFFNDGQRRIDFVLVYEDESRKETNKKGTNEKQRRKRQAYESNL ICHGLQLEATRSVLDDKLVFVKVHAPWEVLCTYAEIMHIKLPLKPNDLKNRSSAFGTLNWFTKVLSVDESIIKPEQEFFTAPFEKNRMND FYIVDRDAFFNPATRSRIVYFILSRVKYQVINNVSKFGINRLVNSGIYKAAFPLHDCKFRRQSEDPSCPNERYLLYREWAHPRSIYKKQP LDLIRKYYGEKIGIYFAWLGYYTQMLLLAAVVGVACFLYGYLNQDNCTWSKEVCHPDIGGKIIMCPQCDRLCPFWKLNITCESSKKLCIF DSFGTLVFAVFMGVWVTLFLEFWKRRQAELEYEWDTVELQQEEQARPEYEARCTHVVINEITQEEERIPFTAWGKCIRITLCASAVFFWI LLIIASVIGIIVYRLSVFIVFSAKLPKNINGTDPIQKYLTPQTATSITASIISFIIIMILNTIYEKVAIMITNFELPRTQTDYENSLTMK MFLFQFVNYYSSCFYIAFFKGKFVGYPGDPVYWLGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEVLLPWIMNLIGRFHRVSGSE KITPRWEQDYHLQPMGKLGLFYEYLEMIIQFGFVTLFVASFPLAPLLALVNNILEIRVDAWKLTTQFRRLVPEKAQDIGAWQPIMQGIAI LAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGDHTSYTMEGYINNTLSIFKVADFKNKSKGNPYSDLGNHTTCRYRDFRYPPGHPQEYKH -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for ANO6-IAPP |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for ANO6-IAPP |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for ANO6-IAPP |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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