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 | Fusion Gene Summary |
| Fusion Gene ORF analysis |
| Fusion Genomic Features |
| Fusion Protein Features |
| Fusion Gene Sequence |
| Fusion Gene PPI analysis |
| Related Drugs |
| Related Diseases |
Fusion gene:LRBA-CASP12 (FusionGDB2 ID:49603) |
Fusion Gene Summary for LRBA-CASP12 |
 Fusion gene summary |
| Fusion gene information | Fusion gene name: LRBA-CASP12 | Fusion gene ID: 49603 | Hgene | Tgene | Gene symbol | LRBA | CASP12 | Gene ID | 987 | 100506742 |
| Gene name | LPS responsive beige-like anchor protein | caspase 12 (gene/pseudogene) | |
| Synonyms | BGL|CDC4L|CVID8|LAB300|LBA | CASP-12|CASP12P1 | |
| Cytomap | 4q31.3 | 11q22.3 | |
| Type of gene | protein-coding | protein-coding | |
| Description | lipopolysaccharide-responsive and beige-like anchor proteinCDC4-like proteinLPS-responsive vesicle trafficking, beach and anchor containingvesicle trafficking, beach and anchor containing | inactive caspase-12caspase 12 pseudogene 1 | |
| Modification date | 20200320 | 20200322 | |
| UniProtAcc | P50851 | . | |
| Ensembl transtripts involved in fusion gene | ENST00000357115, ENST00000507224, ENST00000510413, ENST00000535741, ENST00000503716, | ENST00000375726, ENST00000433738, ENST00000446862, ENST00000447913, ENST00000448103, ENST00000494737, ENST00000508062, ENST00000441710, ENST00000422698, | |
| Fusion gene scores | * DoF score | 31 X 32 X 15=14880 | 2 X 2 X 2=8 |
| # samples | 41 | 2 | |
| ** MAII score | log2(41/14880*10)=-5.18160680648995 possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs). DoF>8 and MAII<0 | log2(2/8*10)=1.32192809488736 | |
| Context | PubMed: LRBA [Title/Abstract] AND CASP12 [Title/Abstract] AND fusion [Title/Abstract] | ||
| Most frequent breakpoint | LRBA(151604703)-CASP12(104768195), # samples:3 | ||
| Anticipated loss of major functional domain due to fusion event. | |||
| * DoF score (Degree of Frequency) = # partners X # break points X # cancer types ** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10) |
| Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez |
| Partner | Gene | GO ID | GO term | PubMed ID |
| Fusion gene breakpoints across LRBA (5'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene breakpoints across CASP12 (3'-gene) * Click on the image to open the UCSC genome browser with custom track showing this image in a new window. |
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| Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0) * All genome coordinats were lifted-over on hg19. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| Source | Disease | Sample | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| ChimerDB4 | BRCA | TCGA-A8-A07L-01A | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
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Fusion Gene ORF analysis for LRBA-CASP12 |
| Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure. * Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser. |
| ORF | Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand |
| 5CDS-intron | ENST00000357115 | ENST00000375726 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000357115 | ENST00000433738 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000357115 | ENST00000446862 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000357115 | ENST00000447913 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000357115 | ENST00000448103 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000357115 | ENST00000494737 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000357115 | ENST00000508062 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000507224 | ENST00000375726 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000507224 | ENST00000433738 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000507224 | ENST00000446862 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000507224 | ENST00000447913 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000507224 | ENST00000448103 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000507224 | ENST00000494737 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000507224 | ENST00000508062 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000510413 | ENST00000375726 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000510413 | ENST00000433738 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000510413 | ENST00000446862 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000510413 | ENST00000447913 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000510413 | ENST00000448103 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000510413 | ENST00000494737 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000510413 | ENST00000508062 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000535741 | ENST00000375726 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000535741 | ENST00000433738 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000535741 | ENST00000446862 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000535741 | ENST00000447913 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000535741 | ENST00000448103 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000535741 | ENST00000494737 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| 5CDS-intron | ENST00000535741 | ENST00000508062 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| Frame-shift | ENST00000357115 | ENST00000441710 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| Frame-shift | ENST00000507224 | ENST00000422698 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| Frame-shift | ENST00000510413 | ENST00000422698 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| Frame-shift | ENST00000535741 | ENST00000441710 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| In-frame | ENST00000357115 | ENST00000422698 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| In-frame | ENST00000507224 | ENST00000441710 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| In-frame | ENST00000510413 | ENST00000441710 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| In-frame | ENST00000535741 | ENST00000422698 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| intron-3CDS | ENST00000503716 | ENST00000422698 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| intron-3CDS | ENST00000503716 | ENST00000441710 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| intron-intron | ENST00000503716 | ENST00000375726 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| intron-intron | ENST00000503716 | ENST00000433738 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| intron-intron | ENST00000503716 | ENST00000446862 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| intron-intron | ENST00000503716 | ENST00000447913 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| intron-intron | ENST00000503716 | ENST00000448103 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| intron-intron | ENST00000503716 | ENST00000494737 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| intron-intron | ENST00000503716 | ENST00000508062 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - |
| ORFfinder result based on the fusion transcript sequence of in-frame fusion genes. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | Seq length (transcript) | BP loci (transcript) | Predicted start (transcript) | Predicted stop (transcript) | Seq length (amino acids) |
| ENST00000535741 | LRBA | chr4 | 151604703 | - | ENST00000422698 | CASP12 | chr11 | 104768195 | - | 7820 | 6395 | 474 | 6398 | 1974 |
| ENST00000510413 | LRBA | chr4 | 151604703 | - | ENST00000441710 | CASP12 | chr11 | 104768195 | - | 7111 | 6206 | 285 | 6209 | 1974 |
| ENST00000357115 | LRBA | chr4 | 151604703 | - | ENST00000422698 | CASP12 | chr11 | 104768195 | - | 7590 | 6165 | 244 | 6168 | 1974 |
| ENST00000507224 | LRBA | chr4 | 151604703 | - | ENST00000441710 | CASP12 | chr11 | 104768195 | - | 7121 | 6216 | 295 | 6219 | 1974 |
| DeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated. |
| Henst | Tenst | Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | No-coding score | Coding score |
| ENST00000535741 | ENST00000422698 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - | 0.002046625 | 0.9979533 |
| ENST00000510413 | ENST00000441710 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - | 0.002038 | 0.997962 |
| ENST00000357115 | ENST00000422698 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - | 0.001413532 | 0.99858654 |
| ENST00000507224 | ENST00000441710 | LRBA | chr4 | 151604703 | - | CASP12 | chr11 | 104768195 | - | 0.002069877 | 0.99793017 |
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Fusion Genomic Features for LRBA-CASP12 |
| FusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints. |
| Hgene | Hchr | Hbp | Hstrand | Tgene | Tchr | Tbp | Tstrand | 1-p | p (fusion gene breakpoint) |
| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page. |
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| Distribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page. |
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Fusion Protein Features for LRBA-CASP12 |
| Four levels of functional features of fusion genes Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr4:151604703/chr11:104768195) - FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels. - How to search 1. Put your fusion gene symbol. 2. Press the tab key until there will be shown the breakpoint information filled. 4. Go down and press 'Search' tab twice. 4. Go down to have the hyperlink of the search result. 5. Click the hyperlink. 6. See the FGviewer result for your fusion gene. |
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| Main function of each fusion partner protein. (from UniProt) |
| Hgene | Tgene |
| LRBA | . |
| FUNCTION: May be involved in coupling signal transduction and vesicle trafficking to enable polarized secretion and/or membrane deposition of immune effector molecules. {ECO:0000250}. | FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}. |
| Retention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at * Minus value of BPloci means that the break pointn is located before the CDS. |
| - In-frame and retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 1006_1053 | 1973 | 2864.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 1006_1053 | 1973 | 2852.0 | Coiled coil | Ontology_term=ECO:0000255 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 1301_1343 | 1973 | 2864.0 | Repeat | Note=WD 1 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 1301_1343 | 1973 | 2852.0 | Repeat | Note=WD 1 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 1531_1548 | 1973 | 2864.0 | Transmembrane | Helical |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 1531_1548 | 1973 | 2852.0 | Transmembrane | Helical |
| Tgene | CASP12 | chr4:151604703 | chr11:104768195 | ENST00000375726 | 0 | 7 | 1_92 | 2 | 342.0 | Domain | CARD | |
| Tgene | CASP12 | chr4:151604703 | chr11:104768195 | ENST00000422698 | 0 | 8 | 1_92 | 2 | 417.6666666666667 | Domain | CARD | |
| Tgene | CASP12 | chr4:151604703 | chr11:104768195 | ENST00000508062 | 0 | 6 | 1_92 | 0 | 258.0 | Domain | CARD |
| - In-frame and not-retained protein feature among the 13 regional features. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Protein feature | Protein feature note |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 1990_1994 | 1973 | 2864.0 | Compositional bias | Note=Poly-Arg |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 1990_1994 | 1973 | 2852.0 | Compositional bias | Note=Poly-Arg |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 2073_2181 | 1973 | 2864.0 | Domain | BEACH-type PH |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 2200_2489 | 1973 | 2864.0 | Domain | BEACH |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 2073_2181 | 1973 | 2852.0 | Domain | BEACH-type PH |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 2200_2489 | 1973 | 2852.0 | Domain | BEACH |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 2591_2633 | 1973 | 2864.0 | Repeat | Note=WD 2 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 2636_2679 | 1973 | 2864.0 | Repeat | Note=WD 3 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 2695_2735 | 1973 | 2864.0 | Repeat | Note=WD 4 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 2777_2816 | 1973 | 2864.0 | Repeat | Note=WD 5 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000357115 | - | 37 | 58 | 2819_2858 | 1973 | 2864.0 | Repeat | Note=WD 6 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 2591_2633 | 1973 | 2852.0 | Repeat | Note=WD 2 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 2636_2679 | 1973 | 2852.0 | Repeat | Note=WD 3 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 2695_2735 | 1973 | 2852.0 | Repeat | Note=WD 4 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 2777_2816 | 1973 | 2852.0 | Repeat | Note=WD 5 |
| Hgene | LRBA | chr4:151604703 | chr11:104768195 | ENST00000510413 | - | 37 | 57 | 2819_2858 | 1973 | 2852.0 | Repeat | Note=WD 6 |
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Fusion Gene Sequence for LRBA-CASP12 |
| For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones. |
| >49603_49603_1_LRBA-CASP12_LRBA_chr4_151604703_ENST00000357115_CASP12_chr11_104768195_ENST00000422698_length(transcript)=7590nt_BP=6165nt AGGGAAACTTGGAGGCTGCGACCAGGGTTTGGCGTTGTTGTCAGCCTCGGGGAGAGAGATTGGACAAATATTCTCCAAGAGGAGGAGGGC GACGCCAAGGACTTTCCACATCAACTGCTTTGGGGTATCTCCACAAGTTGGAAGAGGGACCCTTTCGTTTTGCATTGCGTGTGTTGTGCT CATTACCAGTGCAGCGACTGCCGTCCCAGGGTGACTCTGAGTTGTCCTTTATCGTGAGCTAGCAATGGCTAGCGAAGACAATCGTGTCCC TTCCCCGCCACCAACAGGTGATGACGGGGGAGGTGGAGGGAGAGAAGAAACCCCTACTGAAGGGGGTGCATTGTCTCTGAAACCAGGGCT CCCCATCAGGGGCATCAGAATGAAATTTGCCGTGTTGACCGGTTTGGTTGAAGTTGGAGAAGTATCCAATAGGGATATTGTAGAAACTGT CTTTAACCTGTTGGTAGGAGGACAGTTTGATCTGGAAATGAATTTCATTATCCAAGAAGGTGAGAGTATTAACTGCATGGTGGACCTACT GGAAAAATGTGACATTACGTGCCAAGCAGAAGTCTGGAGCATGTTTACAGCCATTCTGAAGAAAAGCATACGGAATCTTCAAGTCTGCAC TGAAGTAGGCCTTGTTGAAAAAGTGCTTGGGAAAATTGAAAAAGTTGACAATATGATAGCAGATCTTTTGGTTGACATGTTGGGAGTGCT GGCTAGCTATAATTTGACAGTTCGCGAGCTAAAGCTTTTCTTCAGTAAACTTCAAGGAGATAAAGGACGATGGCCTCCACATGCTGGGAA GTTGCTGTCTGTGTTAAAGCATATGCCTCAGAAGTATGGTCCTGATGCCTTTTTTAACTTTCCAGGAAAGAGTGCTGCAGCTATTGCATT ACCTCCTATAGCCAAATGGCCATACCAGAATGGTTTTACATTTCATACATGGCTTAGAATGGATCCTGTAAATAACATCAATGTAGATAA GGATAAACCATATTTGTATTGTTTCAGAACCAGCAAAGGTCTTGGCTATTCTGCTCATTTTGTTGGAGGCTGTTTGATTGTAACATCAAT AAAGTCAAAAGGAAAAGGCTTTCAACACTGTGTGAAATTTGATTTCAAGCCACAAAAGTGGTATATGGTTACCATAGTACACATCTATAA CCGATGGAAGAATAGTGAACTTCGATGTTATGTGAATGGTGAGCTGGCTTCCTATGGAGAGATAACATGGTTTGTCAACACTAGCGATAC CTTTGACAAATGTTTCCTGGGCTCATCAGAAACAGCAGATGCTAATAGAGTATTCTGTGGTCAGATGACTGCAGTTTACCTTTTCAGTGA AGCTCTAAATGCAGCTCAGATATTTGCTATTTATCAGTTGGGCCTGGGATACAAGGGTACATTTAAATTCAAAGCAGAAAGCGACCTTTT CCTTGCTGAGCATCACAAACTTTTATTGTACGATGGGAAACTCTCTAGTGCCATTGCATTCACGTACAATCCACGGGCTACAGATGCCCA GCTTTGTCTTGAATCATCTCCTAAGGACAACCCTTCAATTTTTGTTCATTCACCACATGCACTCATGCTCCAGGATGTAAAGGCAGTTTT AACACATTCCATCCAAAGTGCAATGCATTCAATTGGAGGAGTACAAGTACTATTTCCACTTTTTGCACAGTTGGATTACAGGCAATATTT GTCTGATGAGATTGATTTGACTATATGTTCAACCTTGCTGGCCTTTATCATGGAATTGTTGAAGAACTCAATTGCTATGCAGGAACAGAT GCTTGCCTGTAAGGGCTTCTTGGTAATAGGATATAGCCTTGAAAAGTCTTCCAAATCTCATGTTAGCAGAGCAGTACTTGAACTTTGCCT TGCATTTTCAAAATATCTGAGTAATCTGCAGAATGGGATGCCCCTGCTCAAGCAATTGTGTGATCACGTTCTTCTTAATCCTGCCATATG GATTCATACCCCAGCCAAGGTTCAACTGATGCTCTATACTTATCTGTCCACGGAATTCATTGGTACAGTCAACATATATAACACCATTCG GAGAGTTGGAACAGTGCTTCTCATCATGCACACGCTGAAGTACTACTACTGGGCAGTGAATCCTCAGGATCGAAGTGGTATCACCCCAAA AGGATTAGATGGACCGCGACCTAATCAAAAAGAAATGCTTTCTCTACGAGCATTCTTGTTGATGTTCATTAAGCAATTAGTGATGAAGGA TTCTGGAGTAAAGGAAGATGAATTACAGGCCATTCTTAATTACCTACTGACTATGCATGAGGATGACAATCTAATGGATGTCCTACAGCT GCTTGTTGCATTAATGTCAGAACACCCTAACTCTATGATTCCTGCTTTTGACCAAAGGAATGGGTTACGTGTTATCTACAAACTTCTGGC ATCGAAAAGTGAAGGAATCAGGGTACAAGCTCTTAAGGCAATGGGTTATTTTTTAAAACATCTGGCCCCAAAGAGGAAAGCAGAAGTCAT GCTTGGACATGGATTGTTTTCATTGCTAGCTGAAAGGCTCATGCTTCAGACAAATTTAATCACAATGACCACATATAATGTGCTGTTTGA GATTCTTATAGAACAGATTGGTACTCAGGTGATACATAAACAGCATCCAGATCCTGATTCTTCAGTGAAGATACAAAACCCTCAGATACT AAAAGTAATTGCGACCCTACTTCGAAATTCTCCCCAGTGCCCAGAGAGCATGGAGGTTCGCAGAGCCTTTCTTTCTGACATGATTAAACT TTTTAATAACAGTAGAGAAAACAGGAGGAGCTTGCTACAATGCTCTGTGTGGCAAGAATGGATGCTTTCTCTCTGCTATTTTAATCCTAA GAATTCAGATGAGCAAAAGATAACAGAAATGGTATACGCCATATTCAGAATCCTGCTTTACCATGCAGTCAAATATGAGTGGGGTGGCTG GCGTGTATGGGTAGACACTTTATCAATCACTCATTCAAAGGTCACTTTTGAAATACACAAAGAAAACCTTGCCAATATATTTAGGGAACA GCAAGGAAAAGTTGATGAAGAAATAGGGCTGTGTTCTTCAACTTCAGTTCAAGCAGCCTCTGGCATTAGAAGGGATATTAATGTTTCAGT AGGATCCCAGCAACCAGATACGAAGGATTCTCCTGTCTGTCCTCATTTCACCACAAATGGTAATGAAAATTCAAGTATAGAGAAGACAAG TTCACTAGAATCTGCATCTAATATTGAACTGCAAACTACTAATACATCTTATGAAGAAATGAAAGCTGAGCAAGAAAATCAGGAGTTACC AGATGAAGGCACTTTGGAAGAAACACTGACAAATGAGACAAGGAATGCAGATGATTTAGAAGTATCTTCTGACATAATAGAAGCTGTGGC TATTTCCTCTAATTCTTTTATAACAACTGGCAAAGATTCAATGACTGTCAGTGAAGTAACTGCTTCTATAAGTTCTCCTTCAGAAGAGGA TGCCTCAGAGATGCCAGAATTCTTGGATAAATCTATAGTAGAGGAAGAGGAAGATGATGATTATGTGGAACTGAAAGTAGAAGGCAGTCC TACTGAGGAAGCTAATCTACCCACAGAGCTCCAAGATAACAGTTTGTCTCCAGCTGCATCTGAAGCCGGTGAAAAACTGGACATGTTTGG TAATGATGACAAATTAATATTTCAAGAAGGAAAACCTGTTACTGAAAAGCAAACTGATACTGAAACTCAAGATTCTAAAGATTCTGGAAT TCAGACTATGACAGCATCAGGGTCTTCAGCTATGTCACCAGAAACTACTGTTTCCCAAATAGCTGTAGAATCAGACCTTGGTCAGATGCT GGAGGAAGGGAAGAAAGCAACTAACCTCACTAGAGAAACCAAATTAATTAATGATTGTCATGGTAGTGTCTCTGAGGCTTCTTCTGAGCA AAAGATTGCGAAGTTGGATGTTTCCAATGTTGCTACAGATACTGAGAGGCTGGAGTTGAAGGCCAGTCCCAACGTGGAAGCACCTCAACC TCATCGACATGTGCTTGAGATATCAAGGCAACATGAGCAGCCAGGGCAAGGAATAGCACCAGATGCAGTTAATGGACAAAGGAGGGATTC CAGATCTACTGTGTTTCGTATTCCTGAGTTCAACTGGTCTCAGATGCATCAACGTTTGCTCACTGATCTATTATTTTCAATAGAAACAGA TATACAGATGTGGAGAAGCCATTCAACAAAGACAGTTATGGACTTCGTGAATAGCAGTGATAATGTCATCTTTGTACACAACACAATTCA TCTCATCTCTCAAGTGATGGACAATATGGTCATGGCTTGTGGGGGTATACTGCCATTGCTTTCAGCTGCTACATCGGCTACACATGAACT GGAAAATATTGAACCTACTCAAGGCCTTTCAATAGAAGCCTCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATT TGCAAGTTCTCTTGGCTTTACTGAAATTGAAGCTGAAAAAAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGTTTGTGC AGTCGCAGTAAGGAATTGCTTGGAGTGTCAACAGCATTCACAACTGAAAACTAGGGGAGATAAAGCCTTGAAACCAATGCATAGCCTTAT TCCTTTAGGGAAATCTGCAGCGAAGAGCCCAGTGGACATTGTGACTGGCGGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGA CATGGATATTAATCGGCTTAGGGCAGTTGTTTTCAGAGACATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTT TATCTCTGTTCTTATGGTCTCCAAGTACAGAGACATTTTGGAACCCCAAAATGAAAGGCATAGCCAGTCATGTACAGAAACTGGCAGTGA AAATGAGAATGTATCACTCTCTGAAATCACACCAGCAGCATTCAGCACTTTAACTACGGCATCAGTGGAAGAATCTGAAAGCACATCATC TGCTCGAAGGAGGGACTCAGGCATTGGGGAAGAAACAGCCACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGG TGTCAGTGCAGGCCCAGATGCAATCAGCGAGGTGCTATCTACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAAAAATGATAGAGG AAATGACTTGGACACTAAGGCTACACCGTCAGTTTCAGTTTCAAAAAACGTCAATGTGAAAGACATTCTCCGAAGCTTGGTTAACATACC AGCAGATGGAGTCACAGTGGATCCTGCCCTTCTGCCACCAGCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTT CAGATCTTTTGACAGAAGTGTCATTGTTGCAGCAAAAAAGTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACCTACCAATGCTGT CAGTGTGGTTTCCTCAGTAGATTCAGCCCAAGCCTCAGATATGGGAGGAGAATCACCAGGCAGTAGATCATCTAATGCAAAATTGCCCTC AGTTCCAACAGTTGATTCAGTTTCACAAGATCCGGTTTCAAATATGAGTATTACAGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCC TCTCCTTCGTGAGATTTTTGTGGATTTTGCACCTTTTCTTTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAAC AAGTCTGGTTTGCATGAAGTCGAGTAGTTCAGTTGTGGAATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTCTATTCAGAAGAA TGCAGGCCTTGCTTTTATCGAACTTGTCAATGAAGGAAGGTTGCTTAGCCAGACAATGAAGGATCATCTAGTAAGAGTAGCAAATGAAGC TGAATTTATCCTGAGCAGGCAGAGAGCAGAAGATATTCACAGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACG AGAAGATGAGAAGATGTGTGATCATTTGATAAGAGCAGCAAAATATCGTGACCACGTGACAGCAACTCAACTAATCCAGAAAATTATCAA CATTCTCACAGACAAGCATGGAGCCTGGGGAAATTCTGCAGTGAGATGAGAAACCATCCAACGGTGTTCTGGTCCACATGGTGAAGTTGC TGATCAAGACCTTTCTAGATGGCATTTTTGATGATTTGATGGAAAATAATGTATTAAATACAGATGAGATACACCTTATAGGAAAATGTC TAAAGTTTGTGGTGAGCAATGCTGAAAACCTGGTTGATGATATCACTGAGACAGCTCAAACTGCAGGCAAAATATTTAGGGAACACCTGT GGAATTCCAAAAAACAGCTGAGTTCAGATATATCCAGTGATGGAGAAAGAGAGGCGAACATGCCTGGCCTCAACATCCGCAACAAAGAAT TCAACTATCTTCATAATCGAAATGGTTCTGAACTTGACCTTTTGGGGATGCGAGATCTACTTGAAAACCTTGGATACTCAGTGGTTATAA AAGAGAATCTCACAGCTCAGGAAATGGAAACAGCACTAAGGCAGTTTGCTGCTCACCCAGAGCACCAGTCCTCAGACAGCACATTCCTGG TGTTTATGTCACATAGCATCCTGAATGGAATCTGTGGGACCAAGCACTGGGATCAAGAGCCAGATGTTCTTCACGATGACACCATCTTTG AAATTTTCAACAACCGTAACTGCCAGAGTCTGAAAGACAAACCCAAGGTCATCATCATGCAAGCCTGCCGAGGCAATGGTGCTGGGATTG TTTGGTTCACCACTGACAGTGGAAAAGCCGGTGCAGATACTCATGGTCGGCTCTTGCAAGGTAACATCTGTAATGATGCTGTTACAAAGG CTCATGTGGAAAAGGACTTCATTGCTTTCAAATCTTCCACACCACATAATGTTTCTTGGAGACATGAAACAAATGGCTCTGTCTTCATTT CCCAAATTATCTACTACTTCAGAGAGTATTCTTGGAGTCATCATCTAGAGGAAATTTTTCAAAAGGTTCAACATTCATTTGAGACCCCAA ATATACTGACCCAGCTGCCCACCATTGAAAGACTATCCATGACACGATATTTCTATCTCTTTCCTGGGAATTAAAACTCATAAGAAGCAA CTCAGGAAAATGAAGGCATTATGGTGTCTATGAATCTGCTATTAGAAAAGGTCAATTTTTGATTAAGAATATTTTTATACCAAACTGCTC AGCTGTCCACCTTTTCAAATACCAGGCTAAAATCAATCTCATATTTTTGCTAAATTAATGCTTAATAAATTTTTATTATAAAATTGTGCT TGTTTTCTAATTTTGTCATAAATTAAGTCATGCTTATAGGAGAAAAAATTAAGTATTAAAAATCATAAAAAATGAAGAAATAATCATCAT CAACCTTTTTAAAACTATTCATAAAAACTCAAGTTTTTTATATAGCTTATTTATTTTGTATATCCAATTTTGTGTGCTTTTATTATATTG >49603_49603_1_LRBA-CASP12_LRBA_chr4_151604703_ENST00000357115_CASP12_chr11_104768195_ENST00000422698_length(amino acids)=1974AA_BP= MASEDNRVPSPPPTGDDGGGGGREETPTEGGALSLKPGLPIRGIRMKFAVLTGLVEVGEVSNRDIVETVFNLLVGGQFDLEMNFIIQEGE SINCMVDLLEKCDITCQAEVWSMFTAILKKSIRNLQVCTEVGLVEKVLGKIEKVDNMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDK GRWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIALPPIAKWPYQNGFTFHTWLRMDPVNNINVDKDKPYLYCFRTSKGLGYSAHFV GGCLIVTSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIYNRWKNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSETADANRVFCGQ MTAVYLFSEALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEHHKLLLYDGKLSSAIAFTYNPRATDAQLCLESSPKDNPSIFVHSPHAL MLQDVKAVLTHSIQSAMHSIGGVQVLFPLFAQLDYRQYLSDEIDLTICSTLLAFIMELLKNSIAMQEQMLACKGFLVIGYSLEKSSKSHV SRAVLELCLAFSKYLSNLQNGMPLLKQLCDHVLLNPAIWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWAVNP QDRSGITPKGLDGPRPNQKEMLSLRAFLLMFIKQLVMKDSGVKEDELQAILNYLLTMHEDDNLMDVLQLLVALMSEHPNSMIPAFDQRNG LRVIYKLLASKSEGIRVQALKAMGYFLKHLAPKRKAEVMLGHGLFSLLAERLMLQTNLITMTTYNVLFEILIEQIGTQVIHKQHPDPDSS VKIQNPQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLSLCYFNPKNSDEQKITEMVYAIFRILLYH AVKYEWGGWRVWVDTLSITHSKVTFEIHKENLANIFREQQGKVDEEIGLCSSTSVQAASGIRRDINVSVGSQQPDTKDSPVCPHFTTNGN ENSSIEKTSSLESASNIELQTTNTSYEEMKAEQENQELPDEGTLEETLTNETRNADDLEVSSDIIEAVAISSNSFITTGKDSMTVSEVTA SISSPSEEDASEMPEFLDKSIVEEEEDDDYVELKVEGSPTEEANLPTELQDNSLSPAASEAGEKLDMFGNDDKLIFQEGKPVTEKQTDTE TQDSKDSGIQTMTASGSSAMSPETTVSQIAVESDLGQMLEEGKKATNLTRETKLINDCHGSVSEASSEQKIAKLDVSNVATDTERLELKA SPNVEAPQPHRHVLEISRQHEQPGQGIAPDAVNGQRRDSRSTVFRIPEFNWSQMHQRLLTDLLFSIETDIQMWRSHSTKTVMDFVNSSDN VIFVHNTIHLISQVMDNMVMACGGILPLLSAATSATHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKSMSSGGIL RQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSLIPLGKSAAKSPVDIVTGGISPVRDLDRLLQDMDINRLRAVVFRDIEDSKQAQ FLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGSENENVSLSEITPAAFSTLTTASVEESESTSSARRRDSGIGEETATGLGSHVE VTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATPSVSVSKNVNVKDILRSLVNIPADGVTVDPALLPPACLGALGD LSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPGSRSSNAKLPSVPTVDSVSQDPVSNMSITERL EHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKD -------------------------------------------------------------- >49603_49603_2_LRBA-CASP12_LRBA_chr4_151604703_ENST00000507224_CASP12_chr11_104768195_ENST00000441710_length(transcript)=7121nt_BP=6216nt CCTGCCCTGGATCTCCGCCGCCACCTCGGTCTCGCTGCTCCTGGGCGGGGGGTGAGGACGAGTCCGGAGTATCTGGGGTTTGGCGTTGTT GTCAGCCTCGGGGAGAGAGATTGGACAAATATTCTCCAAGAGGAGGAGGGCGACGCCAAGGACTTTCCACATCAACTGCTTTGGGGTATC TCCACAAGTTGGAAGAGGGACCCTTTCGTTTTGCATTGCGTGTGTTGTGCTCATTACCAGTGCAGCGACTGCCGTCCCAGGGTGACTCTG AGTTGTCCTTTATCGTGAGCTAGCAATGGCTAGCGAAGACAATCGTGTCCCTTCCCCGCCACCAACAGGTGATGACGGGGGAGGTGGAGG GAGAGAAGAAACCCCTACTGAAGGGGGTGCATTGTCTCTGAAACCAGGGCTCCCCATCAGGGGCATCAGAATGAAATTTGCCGTGTTGAC CGGTTTGGTTGAAGTTGGAGAAGTATCCAATAGGGATATTGTAGAAACTGTCTTTAACCTGTTGGTAGGAGGACAGTTTGATCTGGAAAT GAATTTCATTATCCAAGAAGGTGAGAGTATTAACTGCATGGTGGACCTACTGGAAAAATGTGACATTACGTGCCAAGCAGAAGTCTGGAG CATGTTTACAGCCATTCTGAAGAAAAGCATACGGAATCTTCAAGTCTGCACTGAAGTAGGCCTTGTTGAAAAAGTGCTTGGGAAAATTGA AAAAGTTGACAATATGATAGCAGATCTTTTGGTTGACATGTTGGGAGTGCTGGCTAGCTATAATTTGACAGTTCGCGAGCTAAAGCTTTT CTTCAGTAAACTTCAAGGAGATAAAGGACGATGGCCTCCACATGCTGGGAAGTTGCTGTCTGTGTTAAAGCATATGCCTCAGAAGTATGG TCCTGATGCCTTTTTTAACTTTCCAGGAAAGAGTGCTGCAGCTATTGCATTACCTCCTATAGCCAAATGGCCATACCAGAATGGTTTTAC ATTTCATACATGGCTTAGAATGGATCCTGTAAATAACATCAATGTAGATAAGGATAAACCATATTTGTATTGTTTCAGAACCAGCAAAGG TCTTGGCTATTCTGCTCATTTTGTTGGAGGCTGTTTGATTGTAACATCAATAAAGTCAAAAGGAAAAGGCTTTCAACACTGTGTGAAATT TGATTTCAAGCCACAAAAGTGGTATATGGTTACCATAGTACACATCTATAACCGATGGAAGAATAGTGAACTTCGATGTTATGTGAATGG TGAGCTGGCTTCCTATGGAGAGATAACATGGTTTGTCAACACTAGCGATACCTTTGACAAATGTTTCCTGGGCTCATCAGAAACAGCAGA TGCTAATAGAGTATTCTGTGGTCAGATGACTGCAGTTTACCTTTTCAGTGAAGCTCTAAATGCAGCTCAGATATTTGCTATTTATCAGTT GGGCCTGGGATACAAGGGTACATTTAAATTCAAAGCAGAAAGCGACCTTTTCCTTGCTGAGCATCACAAACTTTTATTGTACGATGGGAA ACTCTCTAGTGCCATTGCATTCACGTACAATCCACGGGCTACAGATGCCCAGCTTTGTCTTGAATCATCTCCTAAGGACAACCCTTCAAT TTTTGTTCATTCACCACATGCACTCATGCTCCAGGATGTAAAGGCAGTTTTAACACATTCCATCCAAAGTGCAATGCATTCAATTGGAGG AGTACAAGTACTATTTCCACTTTTTGCACAGTTGGATTACAGGCAATATTTGTCTGATGAGATTGATTTGACTATATGTTCAACCTTGCT GGCCTTTATCATGGAATTGTTGAAGAACTCAATTGCTATGCAGGAACAGATGCTTGCCTGTAAGGGCTTCTTGGTAATAGGATATAGCCT TGAAAAGTCTTCCAAATCTCATGTTAGCAGAGCAGTACTTGAACTTTGCCTTGCATTTTCAAAATATCTGAGTAATCTGCAGAATGGGAT GCCCCTGCTCAAGCAATTGTGTGATCACGTTCTTCTTAATCCTGCCATATGGATTCATACCCCAGCCAAGGTTCAACTGATGCTCTATAC TTATCTGTCCACGGAATTCATTGGTACAGTCAACATATATAACACCATTCGGAGAGTTGGAACAGTGCTTCTCATCATGCACACGCTGAA GTACTACTACTGGGCAGTGAATCCTCAGGATCGAAGTGGTATCACCCCAAAAGGATTAGATGGACCGCGACCTAATCAAAAAGAAATGCT TTCTCTACGAGCATTCTTGTTGATGTTCATTAAGCAATTAGTGATGAAGGATTCTGGAGTAAAGGAAGATGAATTACAGGCCATTCTTAA TTACCTACTGACTATGCATGAGGATGACAATCTAATGGATGTCCTACAGCTGCTTGTTGCATTAATGTCAGAACACCCTAACTCTATGAT TCCTGCTTTTGACCAAAGGAATGGGTTACGTGTTATCTACAAACTTCTGGCATCGAAAAGTGAAGGAATCAGGGTACAAGCTCTTAAGGC AATGGGTTATTTTTTAAAACATCTGGCCCCAAAGAGGAAAGCAGAAGTCATGCTTGGACATGGATTGTTTTCATTGCTAGCTGAAAGGCT CATGCTTCAGACAAATTTAATCACAATGACCACATATAATGTGCTGTTTGAGATTCTTATAGAACAGATTGGTACTCAGGTGATACATAA ACAGCATCCAGATCCTGATTCTTCAGTGAAGATACAAAACCCTCAGATACTAAAAGTAATTGCGACCCTACTTCGAAATTCTCCCCAGTG CCCAGAGAGCATGGAGGTTCGCAGAGCCTTTCTTTCTGACATGATTAAACTTTTTAATAACAGTAGAGAAAACAGGAGGAGCTTGCTACA ATGCTCTGTGTGGCAAGAATGGATGCTTTCTCTCTGCTATTTTAATCCTAAGAATTCAGATGAGCAAAAGATAACAGAAATGGTATACGC CATATTCAGAATCCTGCTTTACCATGCAGTCAAATATGAGTGGGGTGGCTGGCGTGTATGGGTAGACACTTTATCAATCACTCATTCAAA GGTCACTTTTGAAATACACAAAGAAAACCTTGCCAATATATTTAGGGAACAGCAAGGAAAAGTTGATGAAGAAATAGGGCTGTGTTCTTC AACTTCAGTTCAAGCAGCCTCTGGCATTAGAAGGGATATTAATGTTTCAGTAGGATCCCAGCAACCAGATACGAAGGATTCTCCTGTCTG TCCTCATTTCACCACAAATGGTAATGAAAATTCAAGTATAGAGAAGACAAGTTCACTAGAATCTGCATCTAATATTGAACTGCAAACTAC TAATACATCTTATGAAGAAATGAAAGCTGAGCAAGAAAATCAGGAGTTACCAGATGAAGGCACTTTGGAAGAAACACTGACAAATGAGAC AAGGAATGCAGATGATTTAGAAGTATCTTCTGACATAATAGAAGCTGTGGCTATTTCCTCTAATTCTTTTATAACAACTGGCAAAGATTC AATGACTGTCAGTGAAGTAACTGCTTCTATAAGTTCTCCTTCAGAAGAGGATGCCTCAGAGATGCCAGAATTCTTGGATAAATCTATAGT AGAGGAAGAGGAAGATGATGATTATGTGGAACTGAAAGTAGAAGGCAGTCCTACTGAGGAAGCTAATCTACCCACAGAGCTCCAAGATAA CAGTTTGTCTCCAGCTGCATCTGAAGCCGGTGAAAAACTGGACATGTTTGGTAATGATGACAAATTAATATTTCAAGAAGGAAAACCTGT TACTGAAAAGCAAACTGATACTGAAACTCAAGATTCTAAAGATTCTGGAATTCAGACTATGACAGCATCAGGGTCTTCAGCTATGTCACC AGAAACTACTGTTTCCCAAATAGCTGTAGAATCAGACCTTGGTCAGATGCTGGAGGAAGGGAAGAAAGCAACTAACCTCACTAGAGAAAC CAAATTAATTAATGATTGTCATGGTAGTGTCTCTGAGGCTTCTTCTGAGCAAAAGATTGCGAAGTTGGATGTTTCCAATGTTGCTACAGA TACTGAGAGGCTGGAGTTGAAGGCCAGTCCCAACGTGGAAGCACCTCAACCTCATCGACATGTGCTTGAGATATCAAGGCAACATGAGCA GCCAGGGCAAGGAATAGCACCAGATGCAGTTAATGGACAAAGGAGGGATTCCAGATCTACTGTGTTTCGTATTCCTGAGTTCAACTGGTC TCAGATGCATCAACGTTTGCTCACTGATCTATTATTTTCAATAGAAACAGATATACAGATGTGGAGAAGCCATTCAACAAAGACAGTTAT GGACTTCGTGAATAGCAGTGATAATGTCATCTTTGTACACAACACAATTCATCTCATCTCTCAAGTGATGGACAATATGGTCATGGCTTG TGGGGGTATACTGCCATTGCTTTCAGCTGCTACATCGGCTACACATGAACTGGAAAATATTGAACCTACTCAAGGCCTTTCAATAGAAGC CTCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATTTGCAAGTTCTCTTGGCTTTACTGAAATTGAAGCTGAAAA AAGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGTTTGTGCAGTCGCAGTAAGGAATTGCTTGGAGTGTCAACAGCATTC ACAACTGAAAACTAGGGGAGATAAAGCCTTGAAACCAATGCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGAAGAGCCCAGTGGACAT TGTGACTGGCGGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGACATGGATATTAATCGGCTTAGGGCAGTTGTTTTCAGAGA CATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTTTATCTCTGTTCTTATGGTCTCCAAGTACAGAGACATTTT GGAACCCCAAAATGAAAGGCATAGCCAGTCATGTACAGAAACTGGCAGTGAAAATGAGAATGTATCACTCTCTGAAATCACACCAGCAGC ATTCAGCACTTTAACTACGGCATCAGTGGAAGAATCTGAAAGCACATCATCTGCTCGAAGGAGGGACTCAGGCATTGGGGAAGAAACAGC CACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGGTGTCAGTGCAGGCCCAGATGCAATCAGCGAGGTGCTATC TACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAAAAATGATAGAGGAAATGACTTGGACACTAAGGCTACACCGTCAGTTTCAGT TTCAAAAAACGTCAATGTGAAAGACATTCTCCGAAGCTTGGTTAACATACCAGCAGATGGAGTCACAGTGGATCCTGCCCTTCTGCCACC AGCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCATTGTTGCAGCAAAAAA GTCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACCTACCAATGCTGTCAGTGTGGTTTCCTCAGTAGATTCAGCCCAAGCCTCAGA TATGGGAGGAGAATCACCAGGCAGTAGATCATCTAATGCAAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTTCACAAGATCCGGTTTC AAATATGAGTATTACAGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGGATTTTGCACCTTTTCT TTCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAACAAGTCTGGTTTGCATGAAGTCGAGTAGTTCAGTTGTGGA ATTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTCTATTCAGAAGAATGCAGGCCTTGCTTTTATCGAACTTGTCAATGAAGGAAG GTTGCTTAGCCAGACAATGAAGGATCATCTAGTAAGAGTAGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGAGAGCAGAAGATATTCA CAGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACGAGAAGATGAGAAGATGTGTGATCATTTGATAAGAGCAGC AAAATATCGTGACCACGTGACAGCAACTCAACTAATCCAGAAAATTATCAACATTCTCACAGACAAGCATGGAGCCTGGGGAAATTCTGC AGTGAGATGAGAAACCATCCAACGGTGTTCTGGTCCACATGGTGAAGTTGCTGATCAAGACCTTTCTAGATGGCATTTTTGATGATTTGA TGGAAAATAATGTATTAAATACAGATGAGATACACCTTATAGGAAAATGTCTAAAGTTTGTGGTGAGCAATGCTGAAAACCTGGTTGATG ATATCACTGAGACAGCTCAAACTGCAGGCAAAATATTTAGGGAACACCTGTGGAATTCCAAAAAACAGCTGAGTTCAGATATATCCAGTG ATGGAGAAAGAGAGGCGAACATGCCTGGCCTCAACATCCGCAACAAAGAATTCAACTATCTTCATAATCGAAATGGTTCTGAACTTGACC TTTTGGGGATGCGAGATCTACTTGAAAACCTTGGATACTCAGTGGTTATAAAAGAGAATCTCACAGCTCAGGAAATGGAAACAGCACTAA GGCAGTTTGCTGCTCACCCAGAGCACCAGTCCTCAGACAGCACATTCCTGGTGTTTATGTCACATAGCATCCTGAATGGAATCTGTGGGA CCAAGCACTGGGATCAAGAGCCAGATGTTCTTCACGATGACACCATCTTTGAAATTTTCAACAACCGTAACTGCCAGAGTCTGAAAGACA AACCCAAGATGGTGCTGGGATTGTTTGGTTCACCACTGACAGTGGAAAAGCCGGTGCAGATACTCATGGTCGGCTCTTGCAAGGTAACAT CTGTAATGATGCTGTTACAAAGGCTCATGTGGAAAAGGACTTCATTGCTTTCAAATCTTCCACACCACGTTCAACATTCATTTGAGACCC CAAATATACTGACCCAGCTGCCCACCATTGAAAGACTATCCATGACACGATATTTCTATCTCTTTCCTGGGAATTAAAACTCATAAGAAG >49603_49603_2_LRBA-CASP12_LRBA_chr4_151604703_ENST00000507224_CASP12_chr11_104768195_ENST00000441710_length(amino acids)=1974AA_BP= MASEDNRVPSPPPTGDDGGGGGREETPTEGGALSLKPGLPIRGIRMKFAVLTGLVEVGEVSNRDIVETVFNLLVGGQFDLEMNFIIQEGE SINCMVDLLEKCDITCQAEVWSMFTAILKKSIRNLQVCTEVGLVEKVLGKIEKVDNMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDK GRWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIALPPIAKWPYQNGFTFHTWLRMDPVNNINVDKDKPYLYCFRTSKGLGYSAHFV GGCLIVTSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIYNRWKNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSETADANRVFCGQ MTAVYLFSEALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEHHKLLLYDGKLSSAIAFTYNPRATDAQLCLESSPKDNPSIFVHSPHAL MLQDVKAVLTHSIQSAMHSIGGVQVLFPLFAQLDYRQYLSDEIDLTICSTLLAFIMELLKNSIAMQEQMLACKGFLVIGYSLEKSSKSHV SRAVLELCLAFSKYLSNLQNGMPLLKQLCDHVLLNPAIWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWAVNP QDRSGITPKGLDGPRPNQKEMLSLRAFLLMFIKQLVMKDSGVKEDELQAILNYLLTMHEDDNLMDVLQLLVALMSEHPNSMIPAFDQRNG LRVIYKLLASKSEGIRVQALKAMGYFLKHLAPKRKAEVMLGHGLFSLLAERLMLQTNLITMTTYNVLFEILIEQIGTQVIHKQHPDPDSS VKIQNPQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLSLCYFNPKNSDEQKITEMVYAIFRILLYH AVKYEWGGWRVWVDTLSITHSKVTFEIHKENLANIFREQQGKVDEEIGLCSSTSVQAASGIRRDINVSVGSQQPDTKDSPVCPHFTTNGN ENSSIEKTSSLESASNIELQTTNTSYEEMKAEQENQELPDEGTLEETLTNETRNADDLEVSSDIIEAVAISSNSFITTGKDSMTVSEVTA SISSPSEEDASEMPEFLDKSIVEEEEDDDYVELKVEGSPTEEANLPTELQDNSLSPAASEAGEKLDMFGNDDKLIFQEGKPVTEKQTDTE TQDSKDSGIQTMTASGSSAMSPETTVSQIAVESDLGQMLEEGKKATNLTRETKLINDCHGSVSEASSEQKIAKLDVSNVATDTERLELKA SPNVEAPQPHRHVLEISRQHEQPGQGIAPDAVNGQRRDSRSTVFRIPEFNWSQMHQRLLTDLLFSIETDIQMWRSHSTKTVMDFVNSSDN VIFVHNTIHLISQVMDNMVMACGGILPLLSAATSATHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKSMSSGGIL RQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSLIPLGKSAAKSPVDIVTGGISPVRDLDRLLQDMDINRLRAVVFRDIEDSKQAQ FLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGSENENVSLSEITPAAFSTLTTASVEESESTSSARRRDSGIGEETATGLGSHVE VTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATPSVSVSKNVNVKDILRSLVNIPADGVTVDPALLPPACLGALGD LSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPGSRSSNAKLPSVPTVDSVSQDPVSNMSITERL EHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKD -------------------------------------------------------------- >49603_49603_3_LRBA-CASP12_LRBA_chr4_151604703_ENST00000510413_CASP12_chr11_104768195_ENST00000441710_length(transcript)=7111nt_BP=6206nt ATCTCCGCCGCCACCTCGGTCTCGCTGCTCCTGGGCGGGGGGTGAGGACGAGTCCGGAGTATCTGGGGTTTGGCGTTGTTGTCAGCCTCG GGGAGAGAGATTGGACAAATATTCTCCAAGAGGAGGAGGGCGACGCCAAGGACTTTCCACATCAACTGCTTTGGGGTATCTCCACAAGTT GGAAGAGGGACCCTTTCGTTTTGCATTGCGTGTGTTGTGCTCATTACCAGTGCAGCGACTGCCGTCCCAGGGTGACTCTGAGTTGTCCTT TATCGTGAGCTAGCAATGGCTAGCGAAGACAATCGTGTCCCTTCCCCGCCACCAACAGGTGATGACGGGGGAGGTGGAGGGAGAGAAGAA ACCCCTACTGAAGGGGGTGCATTGTCTCTGAAACCAGGGCTCCCCATCAGGGGCATCAGAATGAAATTTGCCGTGTTGACCGGTTTGGTT GAAGTTGGAGAAGTATCCAATAGGGATATTGTAGAAACTGTCTTTAACCTGTTGGTAGGAGGACAGTTTGATCTGGAAATGAATTTCATT ATCCAAGAAGGTGAGAGTATTAACTGCATGGTGGACCTACTGGAAAAATGTGACATTACGTGCCAAGCAGAAGTCTGGAGCATGTTTACA GCCATTCTGAAGAAAAGCATACGGAATCTTCAAGTCTGCACTGAAGTAGGCCTTGTTGAAAAAGTGCTTGGGAAAATTGAAAAAGTTGAC AATATGATAGCAGATCTTTTGGTTGACATGTTGGGAGTGCTGGCTAGCTATAATTTGACAGTTCGCGAGCTAAAGCTTTTCTTCAGTAAA CTTCAAGGAGATAAAGGACGATGGCCTCCACATGCTGGGAAGTTGCTGTCTGTGTTAAAGCATATGCCTCAGAAGTATGGTCCTGATGCC TTTTTTAACTTTCCAGGAAAGAGTGCTGCAGCTATTGCATTACCTCCTATAGCCAAATGGCCATACCAGAATGGTTTTACATTTCATACA TGGCTTAGAATGGATCCTGTAAATAACATCAATGTAGATAAGGATAAACCATATTTGTATTGTTTCAGAACCAGCAAAGGTCTTGGCTAT TCTGCTCATTTTGTTGGAGGCTGTTTGATTGTAACATCAATAAAGTCAAAAGGAAAAGGCTTTCAACACTGTGTGAAATTTGATTTCAAG CCACAAAAGTGGTATATGGTTACCATAGTACACATCTATAACCGATGGAAGAATAGTGAACTTCGATGTTATGTGAATGGTGAGCTGGCT TCCTATGGAGAGATAACATGGTTTGTCAACACTAGCGATACCTTTGACAAATGTTTCCTGGGCTCATCAGAAACAGCAGATGCTAATAGA GTATTCTGTGGTCAGATGACTGCAGTTTACCTTTTCAGTGAAGCTCTAAATGCAGCTCAGATATTTGCTATTTATCAGTTGGGCCTGGGA TACAAGGGTACATTTAAATTCAAAGCAGAAAGCGACCTTTTCCTTGCTGAGCATCACAAACTTTTATTGTACGATGGGAAACTCTCTAGT GCCATTGCATTCACGTACAATCCACGGGCTACAGATGCCCAGCTTTGTCTTGAATCATCTCCTAAGGACAACCCTTCAATTTTTGTTCAT TCACCACATGCACTCATGCTCCAGGATGTAAAGGCAGTTTTAACACATTCCATCCAAAGTGCAATGCATTCAATTGGAGGAGTACAAGTA CTATTTCCACTTTTTGCACAGTTGGATTACAGGCAATATTTGTCTGATGAGATTGATTTGACTATATGTTCAACCTTGCTGGCCTTTATC ATGGAATTGTTGAAGAACTCAATTGCTATGCAGGAACAGATGCTTGCCTGTAAGGGCTTCTTGGTAATAGGATATAGCCTTGAAAAGTCT TCCAAATCTCATGTTAGCAGAGCAGTACTTGAACTTTGCCTTGCATTTTCAAAATATCTGAGTAATCTGCAGAATGGGATGCCCCTGCTC AAGCAATTGTGTGATCACGTTCTTCTTAATCCTGCCATATGGATTCATACCCCAGCCAAGGTTCAACTGATGCTCTATACTTATCTGTCC ACGGAATTCATTGGTACAGTCAACATATATAACACCATTCGGAGAGTTGGAACAGTGCTTCTCATCATGCACACGCTGAAGTACTACTAC TGGGCAGTGAATCCTCAGGATCGAAGTGGTATCACCCCAAAAGGATTAGATGGACCGCGACCTAATCAAAAAGAAATGCTTTCTCTACGA GCATTCTTGTTGATGTTCATTAAGCAATTAGTGATGAAGGATTCTGGAGTAAAGGAAGATGAATTACAGGCCATTCTTAATTACCTACTG ACTATGCATGAGGATGACAATCTAATGGATGTCCTACAGCTGCTTGTTGCATTAATGTCAGAACACCCTAACTCTATGATTCCTGCTTTT GACCAAAGGAATGGGTTACGTGTTATCTACAAACTTCTGGCATCGAAAAGTGAAGGAATCAGGGTACAAGCTCTTAAGGCAATGGGTTAT TTTTTAAAACATCTGGCCCCAAAGAGGAAAGCAGAAGTCATGCTTGGACATGGATTGTTTTCATTGCTAGCTGAAAGGCTCATGCTTCAG ACAAATTTAATCACAATGACCACATATAATGTGCTGTTTGAGATTCTTATAGAACAGATTGGTACTCAGGTGATACATAAACAGCATCCA GATCCTGATTCTTCAGTGAAGATACAAAACCCTCAGATACTAAAAGTAATTGCGACCCTACTTCGAAATTCTCCCCAGTGCCCAGAGAGC ATGGAGGTTCGCAGAGCCTTTCTTTCTGACATGATTAAACTTTTTAATAACAGTAGAGAAAACAGGAGGAGCTTGCTACAATGCTCTGTG TGGCAAGAATGGATGCTTTCTCTCTGCTATTTTAATCCTAAGAATTCAGATGAGCAAAAGATAACAGAAATGGTATACGCCATATTCAGA ATCCTGCTTTACCATGCAGTCAAATATGAGTGGGGTGGCTGGCGTGTATGGGTAGACACTTTATCAATCACTCATTCAAAGGTCACTTTT GAAATACACAAAGAAAACCTTGCCAATATATTTAGGGAACAGCAAGGAAAAGTTGATGAAGAAATAGGGCTGTGTTCTTCAACTTCAGTT CAAGCAGCCTCTGGCATTAGAAGGGATATTAATGTTTCAGTAGGATCCCAGCAACCAGATACGAAGGATTCTCCTGTCTGTCCTCATTTC ACCACAAATGGTAATGAAAATTCAAGTATAGAGAAGACAAGTTCACTAGAATCTGCATCTAATATTGAACTGCAAACTACTAATACATCT TATGAAGAAATGAAAGCTGAGCAAGAAAATCAGGAGTTACCAGATGAAGGCACTTTGGAAGAAACACTGACAAATGAGACAAGGAATGCA GATGATTTAGAAGTATCTTCTGACATAATAGAAGCTGTGGCTATTTCCTCTAATTCTTTTATAACAACTGGCAAAGATTCAATGACTGTC AGTGAAGTAACTGCTTCTATAAGTTCTCCTTCAGAAGAGGATGCCTCAGAGATGCCAGAATTCTTGGATAAATCTATAGTAGAGGAAGAG GAAGATGATGATTATGTGGAACTGAAAGTAGAAGGCAGTCCTACTGAGGAAGCTAATCTACCCACAGAGCTCCAAGATAACAGTTTGTCT CCAGCTGCATCTGAAGCCGGTGAAAAACTGGACATGTTTGGTAATGATGACAAATTAATATTTCAAGAAGGAAAACCTGTTACTGAAAAG CAAACTGATACTGAAACTCAAGATTCTAAAGATTCTGGAATTCAGACTATGACAGCATCAGGGTCTTCAGCTATGTCACCAGAAACTACT GTTTCCCAAATAGCTGTAGAATCAGACCTTGGTCAGATGCTGGAGGAAGGGAAGAAAGCAACTAACCTCACTAGAGAAACCAAATTAATT AATGATTGTCATGGTAGTGTCTCTGAGGCTTCTTCTGAGCAAAAGATTGCGAAGTTGGATGTTTCCAATGTTGCTACAGATACTGAGAGG CTGGAGTTGAAGGCCAGTCCCAACGTGGAAGCACCTCAACCTCATCGACATGTGCTTGAGATATCAAGGCAACATGAGCAGCCAGGGCAA GGAATAGCACCAGATGCAGTTAATGGACAAAGGAGGGATTCCAGATCTACTGTGTTTCGTATTCCTGAGTTCAACTGGTCTCAGATGCAT CAACGTTTGCTCACTGATCTATTATTTTCAATAGAAACAGATATACAGATGTGGAGAAGCCATTCAACAAAGACAGTTATGGACTTCGTG AATAGCAGTGATAATGTCATCTTTGTACACAACACAATTCATCTCATCTCTCAAGTGATGGACAATATGGTCATGGCTTGTGGGGGTATA CTGCCATTGCTTTCAGCTGCTACATCGGCTACACATGAACTGGAAAATATTGAACCTACTCAAGGCCTTTCAATAGAAGCCTCTGTGACA TTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATTTGCAAGTTCTCTTGGCTTTACTGAAATTGAAGCTGAAAAAAGTATGTCA TCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGTTTGTGCAGTCGCAGTAAGGAATTGCTTGGAGTGTCAACAGCATTCACAACTGAAA ACTAGGGGAGATAAAGCCTTGAAACCAATGCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGAAGAGCCCAGTGGACATTGTGACTGGC GGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGACATGGATATTAATCGGCTTAGGGCAGTTGTTTTCAGAGACATAGAGGAT AGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTTTATCTCTGTTCTTATGGTCTCCAAGTACAGAGACATTTTGGAACCCCAA AATGAAAGGCATAGCCAGTCATGTACAGAAACTGGCAGTGAAAATGAGAATGTATCACTCTCTGAAATCACACCAGCAGCATTCAGCACT TTAACTACGGCATCAGTGGAAGAATCTGAAAGCACATCATCTGCTCGAAGGAGGGACTCAGGCATTGGGGAAGAAACAGCCACTGGTTTA GGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGGTGTCAGTGCAGGCCCAGATGCAATCAGCGAGGTGCTATCTACTCTTTCT TTAGAAGTCAATAAGTCTCCGGAAACCAAAAATGATAGAGGAAATGACTTGGACACTAAGGCTACACCGTCAGTTTCAGTTTCAAAAAAC GTCAATGTGAAAGACATTCTCCGAAGCTTGGTTAACATACCAGCAGATGGAGTCACAGTGGATCCTGCCCTTCTGCCACCAGCCTGCCTT GGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCATTGTTGCAGCAAAAAAGTCAGCAGTC TCACCTTCCACCTTTAATACAAGCATACCTACCAATGCTGTCAGTGTGGTTTCCTCAGTAGATTCAGCCCAAGCCTCAGATATGGGAGGA GAATCACCAGGCAGTAGATCATCTAATGCAAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTTCACAAGATCCGGTTTCAAATATGAGT ATTACAGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGGATTTTGCACCTTTTCTTTCTCGGACA CTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAACAAGTCTGGTTTGCATGAAGTCGAGTAGTTCAGTTGTGGAATTGGTTATG CTACTGTGTTCTCAGGAGTGGCAAAATTCTATTCAGAAGAATGCAGGCCTTGCTTTTATCGAACTTGTCAATGAAGGAAGGTTGCTTAGC CAGACAATGAAGGATCATCTAGTAAGAGTAGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGAGAGCAGAAGATATTCACAGACATGCG GAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACGAGAAGATGAGAAGATGTGTGATCATTTGATAAGAGCAGCAAAATATCGT GACCACGTGACAGCAACTCAACTAATCCAGAAAATTATCAACATTCTCACAGACAAGCATGGAGCCTGGGGAAATTCTGCAGTGAGATGA GAAACCATCCAACGGTGTTCTGGTCCACATGGTGAAGTTGCTGATCAAGACCTTTCTAGATGGCATTTTTGATGATTTGATGGAAAATAA TGTATTAAATACAGATGAGATACACCTTATAGGAAAATGTCTAAAGTTTGTGGTGAGCAATGCTGAAAACCTGGTTGATGATATCACTGA GACAGCTCAAACTGCAGGCAAAATATTTAGGGAACACCTGTGGAATTCCAAAAAACAGCTGAGTTCAGATATATCCAGTGATGGAGAAAG AGAGGCGAACATGCCTGGCCTCAACATCCGCAACAAAGAATTCAACTATCTTCATAATCGAAATGGTTCTGAACTTGACCTTTTGGGGAT GCGAGATCTACTTGAAAACCTTGGATACTCAGTGGTTATAAAAGAGAATCTCACAGCTCAGGAAATGGAAACAGCACTAAGGCAGTTTGC TGCTCACCCAGAGCACCAGTCCTCAGACAGCACATTCCTGGTGTTTATGTCACATAGCATCCTGAATGGAATCTGTGGGACCAAGCACTG GGATCAAGAGCCAGATGTTCTTCACGATGACACCATCTTTGAAATTTTCAACAACCGTAACTGCCAGAGTCTGAAAGACAAACCCAAGAT GGTGCTGGGATTGTTTGGTTCACCACTGACAGTGGAAAAGCCGGTGCAGATACTCATGGTCGGCTCTTGCAAGGTAACATCTGTAATGAT GCTGTTACAAAGGCTCATGTGGAAAAGGACTTCATTGCTTTCAAATCTTCCACACCACGTTCAACATTCATTTGAGACCCCAAATATACT GACCCAGCTGCCCACCATTGAAAGACTATCCATGACACGATATTTCTATCTCTTTCCTGGGAATTAAAACTCATAAGAAGCAACTCAGGT >49603_49603_3_LRBA-CASP12_LRBA_chr4_151604703_ENST00000510413_CASP12_chr11_104768195_ENST00000441710_length(amino acids)=1974AA_BP= MASEDNRVPSPPPTGDDGGGGGREETPTEGGALSLKPGLPIRGIRMKFAVLTGLVEVGEVSNRDIVETVFNLLVGGQFDLEMNFIIQEGE SINCMVDLLEKCDITCQAEVWSMFTAILKKSIRNLQVCTEVGLVEKVLGKIEKVDNMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDK GRWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIALPPIAKWPYQNGFTFHTWLRMDPVNNINVDKDKPYLYCFRTSKGLGYSAHFV GGCLIVTSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIYNRWKNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSETADANRVFCGQ MTAVYLFSEALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEHHKLLLYDGKLSSAIAFTYNPRATDAQLCLESSPKDNPSIFVHSPHAL MLQDVKAVLTHSIQSAMHSIGGVQVLFPLFAQLDYRQYLSDEIDLTICSTLLAFIMELLKNSIAMQEQMLACKGFLVIGYSLEKSSKSHV SRAVLELCLAFSKYLSNLQNGMPLLKQLCDHVLLNPAIWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWAVNP QDRSGITPKGLDGPRPNQKEMLSLRAFLLMFIKQLVMKDSGVKEDELQAILNYLLTMHEDDNLMDVLQLLVALMSEHPNSMIPAFDQRNG LRVIYKLLASKSEGIRVQALKAMGYFLKHLAPKRKAEVMLGHGLFSLLAERLMLQTNLITMTTYNVLFEILIEQIGTQVIHKQHPDPDSS VKIQNPQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLSLCYFNPKNSDEQKITEMVYAIFRILLYH AVKYEWGGWRVWVDTLSITHSKVTFEIHKENLANIFREQQGKVDEEIGLCSSTSVQAASGIRRDINVSVGSQQPDTKDSPVCPHFTTNGN ENSSIEKTSSLESASNIELQTTNTSYEEMKAEQENQELPDEGTLEETLTNETRNADDLEVSSDIIEAVAISSNSFITTGKDSMTVSEVTA SISSPSEEDASEMPEFLDKSIVEEEEDDDYVELKVEGSPTEEANLPTELQDNSLSPAASEAGEKLDMFGNDDKLIFQEGKPVTEKQTDTE TQDSKDSGIQTMTASGSSAMSPETTVSQIAVESDLGQMLEEGKKATNLTRETKLINDCHGSVSEASSEQKIAKLDVSNVATDTERLELKA SPNVEAPQPHRHVLEISRQHEQPGQGIAPDAVNGQRRDSRSTVFRIPEFNWSQMHQRLLTDLLFSIETDIQMWRSHSTKTVMDFVNSSDN VIFVHNTIHLISQVMDNMVMACGGILPLLSAATSATHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKSMSSGGIL RQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSLIPLGKSAAKSPVDIVTGGISPVRDLDRLLQDMDINRLRAVVFRDIEDSKQAQ FLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGSENENVSLSEITPAAFSTLTTASVEESESTSSARRRDSGIGEETATGLGSHVE VTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATPSVSVSKNVNVKDILRSLVNIPADGVTVDPALLPPACLGALGD LSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPGSRSSNAKLPSVPTVDSVSQDPVSNMSITERL EHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKD -------------------------------------------------------------- >49603_49603_4_LRBA-CASP12_LRBA_chr4_151604703_ENST00000535741_CASP12_chr11_104768195_ENST00000422698_length(transcript)=7820nt_BP=6395nt AGCACTCGGCGCTGTCATGGCGGCCGGGAGCAGCTTCAGTGGGCACACGACAGCCGCGCGACCCGTGGCGGGGCGAGCTGTGGCAGTAGC ATCCTCACCACTCGCAGCAGCCTCAGCCGCGGCGCCCGTAGCGCCAGCAGCGGCTGCTTTTGCAAAGGCTGAGCGCAGGGGCGGGGCGGG CCAGGAAGCCATGGAGTTCTGTGCAGCCGCGGACTCCCGGGGAGCGGACTAGGGAAACTTGGAGGCTGCGACCAGGGTTTGGCGTTGTTG TCAGCCTCGGGGAGAGAGATTGGACAAATATTCTCCAAGAGGAGGAGGGCGACGCCAAGGACTTTCCACATCAACTGCTTTGGGGTATCT CCACAAGTTGGAAGAGGGACCCTTTCGTTTTGCATTGCGTGTGTTGTGCTCATTACCAGTGCAGCGACTGCCGTCCCAGGGTGACTCTGA GTTGTCCTTTATCGTGAGCTAGCAATGGCTAGCGAAGACAATCGTGTCCCTTCCCCGCCACCAACAGGTGATGACGGGGGAGGTGGAGGG AGAGAAGAAACCCCTACTGAAGGGGGTGCATTGTCTCTGAAACCAGGGCTCCCCATCAGGGGCATCAGAATGAAATTTGCCGTGTTGACC GGTTTGGTTGAAGTTGGAGAAGTATCCAATAGGGATATTGTAGAAACTGTCTTTAACCTGTTGGTAGGAGGACAGTTTGATCTGGAAATG AATTTCATTATCCAAGAAGGTGAGAGTATTAACTGCATGGTGGACCTACTGGAAAAATGTGACATTACGTGCCAAGCAGAAGTCTGGAGC ATGTTTACAGCCATTCTGAAGAAAAGCATACGGAATCTTCAAGTCTGCACTGAAGTAGGCCTTGTTGAAAAAGTGCTTGGGAAAATTGAA AAAGTTGACAATATGATAGCAGATCTTTTGGTTGACATGTTGGGAGTGCTGGCTAGCTATAATTTGACAGTTCGCGAGCTAAAGCTTTTC TTCAGTAAACTTCAAGGAGATAAAGGACGATGGCCTCCACATGCTGGGAAGTTGCTGTCTGTGTTAAAGCATATGCCTCAGAAGTATGGT CCTGATGCCTTTTTTAACTTTCCAGGAAAGAGTGCTGCAGCTATTGCATTACCTCCTATAGCCAAATGGCCATACCAGAATGGTTTTACA TTTCATACATGGCTTAGAATGGATCCTGTAAATAACATCAATGTAGATAAGGATAAACCATATTTGTATTGTTTCAGAACCAGCAAAGGT CTTGGCTATTCTGCTCATTTTGTTGGAGGCTGTTTGATTGTAACATCAATAAAGTCAAAAGGAAAAGGCTTTCAACACTGTGTGAAATTT GATTTCAAGCCACAAAAGTGGTATATGGTTACCATAGTACACATCTATAACCGATGGAAGAATAGTGAACTTCGATGTTATGTGAATGGT GAGCTGGCTTCCTATGGAGAGATAACATGGTTTGTCAACACTAGCGATACCTTTGACAAATGTTTCCTGGGCTCATCAGAAACAGCAGAT GCTAATAGAGTATTCTGTGGTCAGATGACTGCAGTTTACCTTTTCAGTGAAGCTCTAAATGCAGCTCAGATATTTGCTATTTATCAGTTG GGCCTGGGATACAAGGGTACATTTAAATTCAAAGCAGAAAGCGACCTTTTCCTTGCTGAGCATCACAAACTTTTATTGTACGATGGGAAA CTCTCTAGTGCCATTGCATTCACGTACAATCCACGGGCTACAGATGCCCAGCTTTGTCTTGAATCATCTCCTAAGGACAACCCTTCAATT TTTGTTCATTCACCACATGCACTCATGCTCCAGGATGTAAAGGCAGTTTTAACACATTCCATCCAAAGTGCAATGCATTCAATTGGAGGA GTACAAGTACTATTTCCACTTTTTGCACAGTTGGATTACAGGCAATATTTGTCTGATGAGATTGATTTGACTATATGTTCAACCTTGCTG GCCTTTATCATGGAATTGTTGAAGAACTCAATTGCTATGCAGGAACAGATGCTTGCCTGTAAGGGCTTCTTGGTAATAGGATATAGCCTT GAAAAGTCTTCCAAATCTCATGTTAGCAGAGCAGTACTTGAACTTTGCCTTGCATTTTCAAAATATCTGAGTAATCTGCAGAATGGGATG CCCCTGCTCAAGCAATTGTGTGATCACGTTCTTCTTAATCCTGCCATATGGATTCATACCCCAGCCAAGGTTCAACTGATGCTCTATACT TATCTGTCCACGGAATTCATTGGTACAGTCAACATATATAACACCATTCGGAGAGTTGGAACAGTGCTTCTCATCATGCACACGCTGAAG TACTACTACTGGGCAGTGAATCCTCAGGATCGAAGTGGTATCACCCCAAAAGGATTAGATGGACCGCGACCTAATCAAAAAGAAATGCTT TCTCTACGAGCATTCTTGTTGATGTTCATTAAGCAATTAGTGATGAAGGATTCTGGAGTAAAGGAAGATGAATTACAGGCCATTCTTAAT TACCTACTGACTATGCATGAGGATGACAATCTAATGGATGTCCTACAGCTGCTTGTTGCATTAATGTCAGAACACCCTAACTCTATGATT CCTGCTTTTGACCAAAGGAATGGGTTACGTGTTATCTACAAACTTCTGGCATCGAAAAGTGAAGGAATCAGGGTACAAGCTCTTAAGGCA ATGGGTTATTTTTTAAAACATCTGGCCCCAAAGAGGAAAGCAGAAGTCATGCTTGGACATGGATTGTTTTCATTGCTAGCTGAAAGGCTC ATGCTTCAGACAAATTTAATCACAATGACCACATATAATGTGCTGTTTGAGATTCTTATAGAACAGATTGGTACTCAGGTGATACATAAA CAGCATCCAGATCCTGATTCTTCAGTGAAGATACAAAACCCTCAGATACTAAAAGTAATTGCGACCCTACTTCGAAATTCTCCCCAGTGC CCAGAGAGCATGGAGGTTCGCAGAGCCTTTCTTTCTGACATGATTAAACTTTTTAATAACAGTAGAGAAAACAGGAGGAGCTTGCTACAA TGCTCTGTGTGGCAAGAATGGATGCTTTCTCTCTGCTATTTTAATCCTAAGAATTCAGATGAGCAAAAGATAACAGAAATGGTATACGCC ATATTCAGAATCCTGCTTTACCATGCAGTCAAATATGAGTGGGGTGGCTGGCGTGTATGGGTAGACACTTTATCAATCACTCATTCAAAG GTCACTTTTGAAATACACAAAGAAAACCTTGCCAATATATTTAGGGAACAGCAAGGAAAAGTTGATGAAGAAATAGGGCTGTGTTCTTCA ACTTCAGTTCAAGCAGCCTCTGGCATTAGAAGGGATATTAATGTTTCAGTAGGATCCCAGCAACCAGATACGAAGGATTCTCCTGTCTGT CCTCATTTCACCACAAATGGTAATGAAAATTCAAGTATAGAGAAGACAAGTTCACTAGAATCTGCATCTAATATTGAACTGCAAACTACT AATACATCTTATGAAGAAATGAAAGCTGAGCAAGAAAATCAGGAGTTACCAGATGAAGGCACTTTGGAAGAAACACTGACAAATGAGACA AGGAATGCAGATGATTTAGAAGTATCTTCTGACATAATAGAAGCTGTGGCTATTTCCTCTAATTCTTTTATAACAACTGGCAAAGATTCA ATGACTGTCAGTGAAGTAACTGCTTCTATAAGTTCTCCTTCAGAAGAGGATGCCTCAGAGATGCCAGAATTCTTGGATAAATCTATAGTA GAGGAAGAGGAAGATGATGATTATGTGGAACTGAAAGTAGAAGGCAGTCCTACTGAGGAAGCTAATCTACCCACAGAGCTCCAAGATAAC AGTTTGTCTCCAGCTGCATCTGAAGCCGGTGAAAAACTGGACATGTTTGGTAATGATGACAAATTAATATTTCAAGAAGGAAAACCTGTT ACTGAAAAGCAAACTGATACTGAAACTCAAGATTCTAAAGATTCTGGAATTCAGACTATGACAGCATCAGGGTCTTCAGCTATGTCACCA GAAACTACTGTTTCCCAAATAGCTGTAGAATCAGACCTTGGTCAGATGCTGGAGGAAGGGAAGAAAGCAACTAACCTCACTAGAGAAACC AAATTAATTAATGATTGTCATGGTAGTGTCTCTGAGGCTTCTTCTGAGCAAAAGATTGCGAAGTTGGATGTTTCCAATGTTGCTACAGAT ACTGAGAGGCTGGAGTTGAAGGCCAGTCCCAACGTGGAAGCACCTCAACCTCATCGACATGTGCTTGAGATATCAAGGCAACATGAGCAG CCAGGGCAAGGAATAGCACCAGATGCAGTTAATGGACAAAGGAGGGATTCCAGATCTACTGTGTTTCGTATTCCTGAGTTCAACTGGTCT CAGATGCATCAACGTTTGCTCACTGATCTATTATTTTCAATAGAAACAGATATACAGATGTGGAGAAGCCATTCAACAAAGACAGTTATG GACTTCGTGAATAGCAGTGATAATGTCATCTTTGTACACAACACAATTCATCTCATCTCTCAAGTGATGGACAATATGGTCATGGCTTGT GGGGGTATACTGCCATTGCTTTCAGCTGCTACATCGGCTACACATGAACTGGAAAATATTGAACCTACTCAAGGCCTTTCAATAGAAGCC TCTGTGACATTTTTGCAGAGGCTAATTAGCCTTGTGGATGTGCTTATATTTGCAAGTTCTCTTGGCTTTACTGAAATTGAAGCTGAAAAA AGTATGTCATCTGGAGGAATTTTGCGGCAGTGTCTCCGACTAGTTTGTGCAGTCGCAGTAAGGAATTGCTTGGAGTGTCAACAGCATTCA CAACTGAAAACTAGGGGAGATAAAGCCTTGAAACCAATGCATAGCCTTATTCCTTTAGGGAAATCTGCAGCGAAGAGCCCAGTGGACATT GTGACTGGCGGTATATCTCCAGTAAGAGATCTTGACAGGCTTCTACAGGACATGGATATTAATCGGCTTAGGGCAGTTGTTTTCAGAGAC ATAGAGGATAGCAAACAAGCTCAATTTTTAGCCTTGGCAGTAGTATACTTTATCTCTGTTCTTATGGTCTCCAAGTACAGAGACATTTTG GAACCCCAAAATGAAAGGCATAGCCAGTCATGTACAGAAACTGGCAGTGAAAATGAGAATGTATCACTCTCTGAAATCACACCAGCAGCA TTCAGCACTTTAACTACGGCATCAGTGGAAGAATCTGAAAGCACATCATCTGCTCGAAGGAGGGACTCAGGCATTGGGGAAGAAACAGCC ACTGGTTTAGGAAGCCATGTGGAAGTAACTCCTCACACAGCACCTCCTGGTGTCAGTGCAGGCCCAGATGCAATCAGCGAGGTGCTATCT ACTCTTTCTTTAGAAGTCAATAAGTCTCCGGAAACCAAAAATGATAGAGGAAATGACTTGGACACTAAGGCTACACCGTCAGTTTCAGTT TCAAAAAACGTCAATGTGAAAGACATTCTCCGAAGCTTGGTTAACATACCAGCAGATGGAGTCACAGTGGATCCTGCCCTTCTGCCACCA GCCTGCCTTGGAGCCCTTGGTGATCTATCTGTGGAACAACCCGTGCAGTTCAGATCTTTTGACAGAAGTGTCATTGTTGCAGCAAAAAAG TCAGCAGTCTCACCTTCCACCTTTAATACAAGCATACCTACCAATGCTGTCAGTGTGGTTTCCTCAGTAGATTCAGCCCAAGCCTCAGAT ATGGGAGGAGAATCACCAGGCAGTAGATCATCTAATGCAAAATTGCCCTCAGTTCCAACAGTTGATTCAGTTTCACAAGATCCGGTTTCA AATATGAGTATTACAGAGAGGCTTGAACACGCTTTGGAAAAGGCAGCTCCTCTCCTTCGTGAGATTTTTGTGGATTTTGCACCTTTTCTT TCTCGGACACTTTTGGGTAGCCATGGACAAGAACTGCTTATAGAAGGAACAAGTCTGGTTTGCATGAAGTCGAGTAGTTCAGTTGTGGAA TTGGTTATGCTACTGTGTTCTCAGGAGTGGCAAAATTCTATTCAGAAGAATGCAGGCCTTGCTTTTATCGAACTTGTCAATGAAGGAAGG TTGCTTAGCCAGACAATGAAGGATCATCTAGTAAGAGTAGCAAATGAAGCTGAATTTATCCTGAGCAGGCAGAGAGCAGAAGATATTCAC AGACATGCGGAATTTGAGTCACTGTGTGCCCAGTATTCTGCAGACAAACGAGAAGATGAGAAGATGTGTGATCATTTGATAAGAGCAGCA AAATATCGTGACCACGTGACAGCAACTCAACTAATCCAGAAAATTATCAACATTCTCACAGACAAGCATGGAGCCTGGGGAAATTCTGCA GTGAGATGAGAAACCATCCAACGGTGTTCTGGTCCACATGGTGAAGTTGCTGATCAAGACCTTTCTAGATGGCATTTTTGATGATTTGAT GGAAAATAATGTATTAAATACAGATGAGATACACCTTATAGGAAAATGTCTAAAGTTTGTGGTGAGCAATGCTGAAAACCTGGTTGATGA TATCACTGAGACAGCTCAAACTGCAGGCAAAATATTTAGGGAACACCTGTGGAATTCCAAAAAACAGCTGAGTTCAGATATATCCAGTGA TGGAGAAAGAGAGGCGAACATGCCTGGCCTCAACATCCGCAACAAAGAATTCAACTATCTTCATAATCGAAATGGTTCTGAACTTGACCT TTTGGGGATGCGAGATCTACTTGAAAACCTTGGATACTCAGTGGTTATAAAAGAGAATCTCACAGCTCAGGAAATGGAAACAGCACTAAG GCAGTTTGCTGCTCACCCAGAGCACCAGTCCTCAGACAGCACATTCCTGGTGTTTATGTCACATAGCATCCTGAATGGAATCTGTGGGAC CAAGCACTGGGATCAAGAGCCAGATGTTCTTCACGATGACACCATCTTTGAAATTTTCAACAACCGTAACTGCCAGAGTCTGAAAGACAA ACCCAAGGTCATCATCATGCAAGCCTGCCGAGGCAATGGTGCTGGGATTGTTTGGTTCACCACTGACAGTGGAAAAGCCGGTGCAGATAC TCATGGTCGGCTCTTGCAAGGTAACATCTGTAATGATGCTGTTACAAAGGCTCATGTGGAAAAGGACTTCATTGCTTTCAAATCTTCCAC ACCACATAATGTTTCTTGGAGACATGAAACAAATGGCTCTGTCTTCATTTCCCAAATTATCTACTACTTCAGAGAGTATTCTTGGAGTCA TCATCTAGAGGAAATTTTTCAAAAGGTTCAACATTCATTTGAGACCCCAAATATACTGACCCAGCTGCCCACCATTGAAAGACTATCCAT GACACGATATTTCTATCTCTTTCCTGGGAATTAAAACTCATAAGAAGCAACTCAGGAAAATGAAGGCATTATGGTGTCTATGAATCTGCT ATTAGAAAAGGTCAATTTTTGATTAAGAATATTTTTATACCAAACTGCTCAGCTGTCCACCTTTTCAAATACCAGGCTAAAATCAATCTC ATATTTTTGCTAAATTAATGCTTAATAAATTTTTATTATAAAATTGTGCTTGTTTTCTAATTTTGTCATAAATTAAGTCATGCTTATAGG AGAAAAAATTAAGTATTAAAAATCATAAAAAATGAAGAAATAATCATCATCAACCTTTTTAAAACTATTCATAAAAACTCAAGTTTTTTA >49603_49603_4_LRBA-CASP12_LRBA_chr4_151604703_ENST00000535741_CASP12_chr11_104768195_ENST00000422698_length(amino acids)=1974AA_BP= MASEDNRVPSPPPTGDDGGGGGREETPTEGGALSLKPGLPIRGIRMKFAVLTGLVEVGEVSNRDIVETVFNLLVGGQFDLEMNFIIQEGE SINCMVDLLEKCDITCQAEVWSMFTAILKKSIRNLQVCTEVGLVEKVLGKIEKVDNMIADLLVDMLGVLASYNLTVRELKLFFSKLQGDK GRWPPHAGKLLSVLKHMPQKYGPDAFFNFPGKSAAAIALPPIAKWPYQNGFTFHTWLRMDPVNNINVDKDKPYLYCFRTSKGLGYSAHFV GGCLIVTSIKSKGKGFQHCVKFDFKPQKWYMVTIVHIYNRWKNSELRCYVNGELASYGEITWFVNTSDTFDKCFLGSSETADANRVFCGQ MTAVYLFSEALNAAQIFAIYQLGLGYKGTFKFKAESDLFLAEHHKLLLYDGKLSSAIAFTYNPRATDAQLCLESSPKDNPSIFVHSPHAL MLQDVKAVLTHSIQSAMHSIGGVQVLFPLFAQLDYRQYLSDEIDLTICSTLLAFIMELLKNSIAMQEQMLACKGFLVIGYSLEKSSKSHV SRAVLELCLAFSKYLSNLQNGMPLLKQLCDHVLLNPAIWIHTPAKVQLMLYTYLSTEFIGTVNIYNTIRRVGTVLLIMHTLKYYYWAVNP QDRSGITPKGLDGPRPNQKEMLSLRAFLLMFIKQLVMKDSGVKEDELQAILNYLLTMHEDDNLMDVLQLLVALMSEHPNSMIPAFDQRNG LRVIYKLLASKSEGIRVQALKAMGYFLKHLAPKRKAEVMLGHGLFSLLAERLMLQTNLITMTTYNVLFEILIEQIGTQVIHKQHPDPDSS VKIQNPQILKVIATLLRNSPQCPESMEVRRAFLSDMIKLFNNSRENRRSLLQCSVWQEWMLSLCYFNPKNSDEQKITEMVYAIFRILLYH AVKYEWGGWRVWVDTLSITHSKVTFEIHKENLANIFREQQGKVDEEIGLCSSTSVQAASGIRRDINVSVGSQQPDTKDSPVCPHFTTNGN ENSSIEKTSSLESASNIELQTTNTSYEEMKAEQENQELPDEGTLEETLTNETRNADDLEVSSDIIEAVAISSNSFITTGKDSMTVSEVTA SISSPSEEDASEMPEFLDKSIVEEEEDDDYVELKVEGSPTEEANLPTELQDNSLSPAASEAGEKLDMFGNDDKLIFQEGKPVTEKQTDTE TQDSKDSGIQTMTASGSSAMSPETTVSQIAVESDLGQMLEEGKKATNLTRETKLINDCHGSVSEASSEQKIAKLDVSNVATDTERLELKA SPNVEAPQPHRHVLEISRQHEQPGQGIAPDAVNGQRRDSRSTVFRIPEFNWSQMHQRLLTDLLFSIETDIQMWRSHSTKTVMDFVNSSDN VIFVHNTIHLISQVMDNMVMACGGILPLLSAATSATHELENIEPTQGLSIEASVTFLQRLISLVDVLIFASSLGFTEIEAEKSMSSGGIL RQCLRLVCAVAVRNCLECQQHSQLKTRGDKALKPMHSLIPLGKSAAKSPVDIVTGGISPVRDLDRLLQDMDINRLRAVVFRDIEDSKQAQ FLALAVVYFISVLMVSKYRDILEPQNERHSQSCTETGSENENVSLSEITPAAFSTLTTASVEESESTSSARRRDSGIGEETATGLGSHVE VTPHTAPPGVSAGPDAISEVLSTLSLEVNKSPETKNDRGNDLDTKATPSVSVSKNVNVKDILRSLVNIPADGVTVDPALLPPACLGALGD LSVEQPVQFRSFDRSVIVAAKKSAVSPSTFNTSIPTNAVSVVSSVDSAQASDMGGESPGSRSSNAKLPSVPTVDSVSQDPVSNMSITERL EHALEKAAPLLREIFVDFAPFLSRTLLGSHGQELLIEGTSLVCMKSSSSVVELVMLLCSQEWQNSIQKNAGLAFIELVNEGRLLSQTMKD -------------------------------------------------------------- |
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Fusion Gene PPI Analysis for LRBA-CASP12 |
| Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in |
| Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160) |
| Hgene | Hgene's interactors | Tgene | Tgene's interactors |
| - Retained PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Still interaction with |
| - Lost PPIs in in-frame fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
| - Retained PPIs, but lost function due to frame-shift fusion. |
| Partner | Gene | Hbp | Tbp | ENST | Strand | BPexon | TotalExon | Protein feature loci | *BPloci | TotalLen | Interaction lost with |
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Related Drugs for LRBA-CASP12 |
| Drugs targeting genes involved in this fusion gene. (DrugBank Version 5.1.8 2021-05-08) |
| Partner | Gene | UniProtAcc | DrugBank ID | Drug name | Drug activity | Drug type | Drug status |
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Related Diseases for LRBA-CASP12 |
| Diseases associated with fusion partners. (DisGeNet 4.0) |
| Partner | Gene | Disease ID | Disease name | # pubmeds | Source |
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