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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:LRIG1-BDH1 (FusionGDB2 ID:49672)

Fusion Gene Summary for LRIG1-BDH1

check button Fusion gene summary
Fusion gene informationFusion gene name: LRIG1-BDH1
Fusion gene ID: 49672
HgeneTgene
Gene symbol

LRIG1

BDH1

Gene ID

26018

622

Gene nameleucine rich repeats and immunoglobulin like domains 13-hydroxybutyrate dehydrogenase 1
SynonymsLIG-1|LIG1BDH|SDR9C1
Cytomap

3p14.1

3q29

Type of geneprotein-codingprotein-coding
Descriptionleucine-rich repeats and immunoglobulin-like domains protein 1leucine-rich repeat protein LRIG1ortholog of mouse integral membrane glycoprotein LIG-1D-beta-hydroxybutyrate dehydrogenase, mitochondrial(R)-3-hydroxybutyrate dehydrogenase3-hydroxybutyrate dehydrogenase (heart, mitochondrial)3-hydroxybutyrate dehydrogenase, type 1epididymis secretory sperm binding proteinshort chain dehydrogenase/red
Modification date2020032020200313
UniProtAcc

Q96JA1

Q02338

Ensembl transtripts involved in fusion geneENST00000273261, ENST00000383703, 
ENST00000496559, 		ENST00000441275, 
ENST00000476764, ENST00000358186, 
ENST00000392378, ENST00000392379, 
Fusion gene scores* DoF score11 X 13 X 6=8588 X 8 X 8=512
# samples 1414
** MAII scorelog2(14/858*10)=-2.61555082055458
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/512*10)=-1.87071698305503
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: LRIG1 [Title/Abstract] AND BDH1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointLRIG1(66501983)-BDH1(197260432), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID

check buttonFusion gene breakpoints across LRIG1 (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across BDH1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4UCECTCGA-FI-A2CY-01ALRIG1chr3

66501983

-BDH1chr3

197260432

-


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Fusion Gene ORF analysis for LRIG1-BDH1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000273261ENST00000441275LRIG1chr3

66501983

-BDH1chr3

197260432

-
5CDS-5UTRENST00000383703ENST00000441275LRIG1chr3

66501983

-BDH1chr3

197260432

-
5CDS-intronENST00000273261ENST00000476764LRIG1chr3

66501983

-BDH1chr3

197260432

-
5CDS-intronENST00000383703ENST00000476764LRIG1chr3

66501983

-BDH1chr3

197260432

-
In-frameENST00000273261ENST00000358186LRIG1chr3

66501983

-BDH1chr3

197260432

-
In-frameENST00000273261ENST00000392378LRIG1chr3

66501983

-BDH1chr3

197260432

-
In-frameENST00000273261ENST00000392379LRIG1chr3

66501983

-BDH1chr3

197260432

-
In-frameENST00000383703ENST00000358186LRIG1chr3

66501983

-BDH1chr3

197260432

-
In-frameENST00000383703ENST00000392378LRIG1chr3

66501983

-BDH1chr3

197260432

-
In-frameENST00000383703ENST00000392379LRIG1chr3

66501983

-BDH1chr3

197260432

-
intron-3CDSENST00000496559ENST00000358186LRIG1chr3

66501983

-BDH1chr3

197260432

-
intron-3CDSENST00000496559ENST00000392378LRIG1chr3

66501983

-BDH1chr3

197260432

-
intron-3CDSENST00000496559ENST00000392379LRIG1chr3

66501983

-BDH1chr3

197260432

-
intron-5UTRENST00000496559ENST00000441275LRIG1chr3

66501983

-BDH1chr3

197260432

-
intron-intronENST00000496559ENST00000476764LRIG1chr3

66501983

-BDH1chr3

197260432

-

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000273261LRIG1chr366501983-ENST00000392379BDH1chr3197260432-39518901441838564
ENST00000273261LRIG1chr366501983-ENST00000392378BDH1chr3197260432-39518901441838564
ENST00000273261LRIG1chr366501983-ENST00000358186BDH1chr3197260432-39518901441838564
ENST00000383703LRIG1chr366501983-ENST00000392379BDH1chr3197260432-4030969101917635
ENST00000383703LRIG1chr366501983-ENST00000392378BDH1chr3197260432-4030969101917635
ENST00000383703LRIG1chr366501983-ENST00000358186BDH1chr3197260432-4030969101917635

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000273261ENST00000392379LRIG1chr366501983-BDH1chr3197260432-0.0030643220.9969357
ENST00000273261ENST00000392378LRIG1chr366501983-BDH1chr3197260432-0.0030643220.9969357
ENST00000273261ENST00000358186LRIG1chr366501983-BDH1chr3197260432-0.0030643220.9969357
ENST00000383703ENST00000392379LRIG1chr366501983-BDH1chr3197260432-0.003063890.9969361
ENST00000383703ENST00000392378LRIG1chr366501983-BDH1chr3197260432-0.003063890.9969361
ENST00000383703ENST00000358186LRIG1chr366501983-BDH1chr3197260432-0.003063890.9969361

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Fusion Genomic Features for LRIG1-BDH1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.

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Fusion Protein Features for LRIG1-BDH1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr3:66501983/chr3:197260432)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
LRIG1

Q96JA1

BDH1

Q02338

FUNCTION: Acts as a feedback negative regulator of signaling by receptor tyrosine kinases, through a mechanism that involves enhancement of receptor ubiquitination and accelerated intracellular degradation. {ECO:0000269|PubMed:15282549}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-31935_681211094.0DomainNote=LRRNT
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-32035_681211071.0DomainNote=LRRNT
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-31969_901211094.0RepeatNote=LRR 1
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-31993_1141211094.0RepeatNote=LRR 2
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-32069_901211071.0RepeatNote=LRR 1
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-32093_1141211071.0RepeatNote=LRR 2
TgeneBDH1chr3:66501983chr3:197260432ENST000003581861759_8327344.0Nucleotide bindingNAD
TgeneBDH1chr3:66501983chr3:197260432ENST000003923781759_8327344.0Nucleotide bindingNAD
TgeneBDH1chr3:66501983chr3:197260432ENST000003923792859_8327344.0Nucleotide bindingNAD

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319520_5241211094.0Compositional biasNote=Poly-Ser
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320520_5241211071.0Compositional biasNote=Poly-Ser
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319440_4911211094.0DomainNote=LRRCT
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319495_5941211094.0DomainNote=Ig-like C2-type 1
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319599_6881211094.0DomainNote=Ig-like C2-type 2
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319693_7791211094.0DomainNote=Ig-like C2-type 3
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320440_4911211071.0DomainNote=LRRCT
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320495_5941211071.0DomainNote=Ig-like C2-type 1
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320599_6881211071.0DomainNote=Ig-like C2-type 2
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320693_7791211071.0DomainNote=Ig-like C2-type 3
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319116_1371211094.0RepeatNote=LRR 3
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319140_1611211094.0RepeatNote=LRR 4
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319164_1851211094.0RepeatNote=LRR 5
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319189_2101211094.0RepeatNote=LRR 6
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319212_2331211094.0RepeatNote=LRR 7
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319236_2571211094.0RepeatNote=LRR 8
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319260_2811211094.0RepeatNote=LRR 9
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319284_3051211094.0RepeatNote=LRR 10
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319308_3291211094.0RepeatNote=LRR 11
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319332_3531211094.0RepeatNote=LRR 12
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319356_3781211094.0RepeatNote=LRR 13
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319383_4041211094.0RepeatNote=LRR 14
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319407_4281211094.0RepeatNote=LRR 15
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320116_1371211071.0RepeatNote=LRR 3
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320140_1611211071.0RepeatNote=LRR 4
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320164_1851211071.0RepeatNote=LRR 5
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320189_2101211071.0RepeatNote=LRR 6
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320212_2331211071.0RepeatNote=LRR 7
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320236_2571211071.0RepeatNote=LRR 8
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320260_2811211071.0RepeatNote=LRR 9
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320284_3051211071.0RepeatNote=LRR 10
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320308_3291211071.0RepeatNote=LRR 11
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320332_3531211071.0RepeatNote=LRR 12
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320356_3781211071.0RepeatNote=LRR 13
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320383_4041211071.0RepeatNote=LRR 14
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320407_4281211071.0RepeatNote=LRR 15
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-31935_7941211094.0Topological domainExtracellular
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319816_10931211094.0Topological domainCytoplasmic
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-32035_7941211071.0Topological domainExtracellular
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320816_10931211071.0Topological domainCytoplasmic
HgeneLRIG1chr3:66501983chr3:197260432ENST00000273261-319795_8151211094.0TransmembraneHelical
HgeneLRIG1chr3:66501983chr3:197260432ENST00000383703-320795_8151211071.0TransmembraneHelical


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Fusion Gene Sequence for LRIG1-BDH1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>49672_49672_1_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000273261_BDH1_chr3_197260432_ENST00000358186_length(transcript)=3951nt_BP=890nt
GCTCTCTGGCCGCGGCGTGGGGACAGCGAGGCGCACTGGGGCCTCCCAGCGCGGGGCCGGCCGCGCCGTCCAGCCCGAGGTCTACGGCTT
TGCGCTCCGAGCCCAGAGGAAGATGCCTGCCGGCACCGAGCTCGGGCTGCGGGGCTGAACGCCTGTCTTCCAGGCGCAGCGGCAGCACTG
CCCTCGGCCGGTGTCGGTAGCGGCACTCGGCGTGCCCCGGGCGGACGAAGAGCGCAGGCTGGGTACACCTTGCCCGAATCGGCGGAGTTC
GCAGCTAGCGCGGGCGGGCCGGCCGGCCCGGATGGGCGCGGGGTTTGCGGCCCCCGCCGGGTGCTCCGGAGCGGCCCGGGCACCGGGGGC
ACGCTGAGTGCCGGAGCCGCGGCCGCAGAGAGAACTTGGGGCGGGGGCCATGCCCCGGTGCGGAGTCTAGAGCCGAGCGGAGCGCCCCGC
GGGCCCGCCCGCGTCTGCGGCCGTTCGGGTCCTCACAGTCCCCGCGCCCGGAGTTCGCAGCGCGCTCCAGACAAGATGGCGCGGCCGGTC
CGGGGAGGGCTCGGGGCCCCGCGCCGCTCGCCTTGCCTTCTCCTTCTCTGGCTGCTTTTGCTTCGGCTGGAGCCGGTGACCGCCGCGGCC
GGCCCGCGGGCGCCCTGCGCGGCCGCCTGCACTTGCGCTGGGGACTCGCTGGACTGCGGTGGGCGCGGGCTGGCTGCGTTGCCCGGGGAC
CTGCCCTCCTGGACGCGGAGCCTAAACCTGAGTTACAACAAACTCTCTGAGATTGACCCTGCTGGTTTTGAGGACTTGCCGAACCTACAG
GAAGTGTACCTCAATAATAATGAGTTGACAGCGGTACCATCCCTGGGCGCTGCTTCATCACATGTCGTCTCTCTCTTTCTACGCCCACTA
TTGCTTGGTTCTACTTCCTTTATCCCGATTGGCCGTCGGACTTATGCCAGTGCGGCGGAGCCGGTTGGCAGCAAAGCTGTCCTGGTCACA
GGCTGTGACTCTGGATTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTCCTTGTGTTTGCTGGCTGCTTGATGAAGGACAAA
GGCCATGATGGGGTCAAGGAGCTGGACAGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAGCGAAGAGGTGGAG
AAAGTGGTGGAGATTGTCCGCTCGAGCCTGAAGGACCCTGAGAAAGGCATGTGGGGCCTCGTTAACAATGCCGGCATCTCAACGTTCGGG
GAGGTGGAGTTCACCAGCCTGGAGACCTACAAGCAGGTGGCAGAAGTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTCCCC
CTCATCCGAAGGGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCATGGCCAACCCGGCCCGCTCCCCGTACTGCATCACC
AAGTTCGGGGTAGAGGCTTTCTCGGACTGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGTCAGCGTGGTGGAGCCCGGCAACTTC
ATCGCTGCCACCAGCCTTTACAGCCCTGAGAGCATTCAGGCCATCGCCAAGAAGATGTGGGAGGAGCTGCCTGAGGTCGTGCGCAAGGAC
TACGGCAAGAAGTACTTTGATGAAAAGATCGCCAAGATGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCGATGCT
GTCACACACGCCCTGACCGCCACCACCCCCTACACCCGCTACCACCCCATGGACTACTACTGGTGGCTGCGAATGCAGATCATGACCCAC
TTGCCTGGAGCCATCTCCGACATGATCTACATCCGCTGAAGAGTCTCGCTGTGGCCTCTGTCAGGGATCCCTGGTGGAAGGGGAGGGGAG
GGAGGAACCCATATAGTCAACTCTTGATTATCCACGTGTGGATTATCCACCATGCCAGGAAGACCCATAACTGGTTTTAACACTAACTAG
AGGGAATGACTTCTTTGCATAGTGAGTGACTTGGGCCTTCACAAACAGGGTGTGGAGTGGCAGGCAGAGGCCTCTAAATCTCAGGGCAAA
CATGGTGAATCTATCTCTCCGGAGATAATTTCATACAGAGATTTTAAGAAAACATCTTTATATTAAAAACAGATCTCATTTGATCCTTAA
GCCAGTCTCATGAATGAAAAGGACAGGTTTTTTTCTTTTGTAAATGAAGCATTTGCAGCTTAAAGAGGATGCATGAAATAACCCTTTTAT
CGCTTATAAATAGTGCCAGTTATGTGTTCCTGCCACGGCTGTGGAAATACTTCACATTTGCATTCCAGGACTGTTTTGGATCCATTTGCC
CGAGAATCTTCTGACTAACTCTGTGTCCTCATCTGGGCAGCACACACCAAGTGCCCACTGGTACCTCTGCATGTCCATGGTGCTGTGTGA
CTGGCCAGCCAGCAGCCAGTGACTCAGAGCTGGCTGTATGGAGGGGGTGGGAATGTTTCTGGAGATTTTTGTTTTTCCAGACACAGTCTT
GCTCAGTCCCCTAGGCTGGAGTGCAATGGCACCATCTCCGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCGGTTCTCCTGCCTCAGCC
TTCCAAGTAGCTGGGGTTATAGGCACCCACCACCATGCCGGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCTAG
GCTGGTCCCGAACTCCCGACTTCAAGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGATTTTTACTTGAGATT
TTTCCATCCTCTTTTAGGACTCAGGATAGACTTGTGTGGAGGTGCTCTCTGGCTAAGGGGATAAGTTGTTACTGGTTTGGGTCTGCTTGG
TTTTGCCTTGGGTGGGGCCGGTGTCGATGGGGCAGGCTTGGCACGAGCAGTGGTGCCATGGCAGGGCACTGTGGCATCTCCCCTAGCAGT
GGATTTGGGGTCCCTGCTTGCCTCACGTGGTGCTTACACACATGTACACACACACACACACACACACACACACACACACCTTACACACAT
GTACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACCCCTGTTCTGCAGGGC
TTCAGCGTGGCCTTCATTCCCGCCTCGCCTCGGCCTCTTTTCAATTAAGAAGTGATGCCACTTGAGGCAGGGTCTGCATGATCACTTCTT
GGGTTTCAGTTTGAAAGCTGCCATCCCTGCGACTGCCCAGGGCCTGTATGTTGGGACCGAAGCCAAACACCACTGTCCTCCAGGGGGCTT
TCGGCCCGGGGCAGGGTCCCCAGTGCCCGCCTTCGAATCAGACTCCGCGTTTCCGCCTCTCCCTGGGCGGACCTGCCGCTAGAGGGCGCT
CCTCCTCCGCAGCCGGCGCCGGCCTCCAGCGCCCCAGACTCCCGCGCTGCCGCCCGAGCCTGAGGTTTCTCACGGCGTTCGGGATTCGCG
CTTCGGAAACCGGGAACAAAGAAGCAAGCAGCACCCTTCAGAAACAGTGTTCTCGCTCTCCTAGCAGCTGGCCCGGGCCCGGAGGCTGGT
GCCAGGAGAAGGCAGAAGAGCCCGGGCAGCCGGAGTGGGCTACGGGGTTCAGGCAGTGCCAAGGAAGAAGGGCCTCACAATGGGCAATTC
AGCTGCCTCCCGGGCCGTTGTCCCCGCTGTCTTCAAACAGGGGTCCCCTGTCCCAGCTGCCCCAGGAGGAGGGGGGGAGGCAGGCAGGGC
CGAAACCCTCCAGAGCCCAGAGGGGGACGCTTGGTGGCCGCTGCAGTTACATAACCATAGGATGCTTTTGTACCGTGGACCTTGTTCTAG

>49672_49672_1_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000273261_BDH1_chr3_197260432_ENST00000358186_length(amino acids)=564AA_BP=249
MNACLPGAAAALPSAGVGSGTRRAPGGRRAQAGYTLPESAEFAASAGGPAGPDGRGVCGPRRVLRSGPGTGGTLSAGAAAAERTWGGGHA
PVRSLEPSGAPRGPARVCGRSGPHSPRARSSQRAPDKMARPVRGGLGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLD
CGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLRPLLLGSTSFIPIGRRTYASA
AEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMW
GLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPL
GVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMD

--------------------------------------------------------------
>49672_49672_2_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000273261_BDH1_chr3_197260432_ENST00000392378_length(transcript)=3951nt_BP=890nt
GCTCTCTGGCCGCGGCGTGGGGACAGCGAGGCGCACTGGGGCCTCCCAGCGCGGGGCCGGCCGCGCCGTCCAGCCCGAGGTCTACGGCTT
TGCGCTCCGAGCCCAGAGGAAGATGCCTGCCGGCACCGAGCTCGGGCTGCGGGGCTGAACGCCTGTCTTCCAGGCGCAGCGGCAGCACTG
CCCTCGGCCGGTGTCGGTAGCGGCACTCGGCGTGCCCCGGGCGGACGAAGAGCGCAGGCTGGGTACACCTTGCCCGAATCGGCGGAGTTC
GCAGCTAGCGCGGGCGGGCCGGCCGGCCCGGATGGGCGCGGGGTTTGCGGCCCCCGCCGGGTGCTCCGGAGCGGCCCGGGCACCGGGGGC
ACGCTGAGTGCCGGAGCCGCGGCCGCAGAGAGAACTTGGGGCGGGGGCCATGCCCCGGTGCGGAGTCTAGAGCCGAGCGGAGCGCCCCGC
GGGCCCGCCCGCGTCTGCGGCCGTTCGGGTCCTCACAGTCCCCGCGCCCGGAGTTCGCAGCGCGCTCCAGACAAGATGGCGCGGCCGGTC
CGGGGAGGGCTCGGGGCCCCGCGCCGCTCGCCTTGCCTTCTCCTTCTCTGGCTGCTTTTGCTTCGGCTGGAGCCGGTGACCGCCGCGGCC
GGCCCGCGGGCGCCCTGCGCGGCCGCCTGCACTTGCGCTGGGGACTCGCTGGACTGCGGTGGGCGCGGGCTGGCTGCGTTGCCCGGGGAC
CTGCCCTCCTGGACGCGGAGCCTAAACCTGAGTTACAACAAACTCTCTGAGATTGACCCTGCTGGTTTTGAGGACTTGCCGAACCTACAG
GAAGTGTACCTCAATAATAATGAGTTGACAGCGGTACCATCCCTGGGCGCTGCTTCATCACATGTCGTCTCTCTCTTTCTACGCCCACTA
TTGCTTGGTTCTACTTCCTTTATCCCGATTGGCCGTCGGACTTATGCCAGTGCGGCGGAGCCGGTTGGCAGCAAAGCTGTCCTGGTCACA
GGCTGTGACTCTGGATTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTCCTTGTGTTTGCTGGCTGCTTGATGAAGGACAAA
GGCCATGATGGGGTCAAGGAGCTGGACAGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAGCGAAGAGGTGGAG
AAAGTGGTGGAGATTGTCCGCTCGAGCCTGAAGGACCCTGAGAAAGGCATGTGGGGCCTCGTTAACAATGCCGGCATCTCAACGTTCGGG
GAGGTGGAGTTCACCAGCCTGGAGACCTACAAGCAGGTGGCAGAAGTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTCCCC
CTCATCCGAAGGGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCATGGCCAACCCGGCCCGCTCCCCGTACTGCATCACC
AAGTTCGGGGTAGAGGCTTTCTCGGACTGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGTCAGCGTGGTGGAGCCCGGCAACTTC
ATCGCTGCCACCAGCCTTTACAGCCCTGAGAGCATTCAGGCCATCGCCAAGAAGATGTGGGAGGAGCTGCCTGAGGTCGTGCGCAAGGAC
TACGGCAAGAAGTACTTTGATGAAAAGATCGCCAAGATGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCGATGCT
GTCACACACGCCCTGACCGCCACCACCCCCTACACCCGCTACCACCCCATGGACTACTACTGGTGGCTGCGAATGCAGATCATGACCCAC
TTGCCTGGAGCCATCTCCGACATGATCTACATCCGCTGAAGAGTCTCGCTGTGGCCTCTGTCAGGGATCCCTGGTGGAAGGGGAGGGGAG
GGAGGAACCCATATAGTCAACTCTTGATTATCCACGTGTGGATTATCCACCATGCCAGGAAGACCCATAACTGGTTTTAACACTAACTAG
AGGGAATGACTTCTTTGCATAGTGAGTGACTTGGGCCTTCACAAACAGGGTGTGGAGTGGCAGGCAGAGGCCTCTAAATCTCAGGGCAAA
CATGGTGAATCTATCTCTCCGGAGATAATTTCATACAGAGATTTTAAGAAAACATCTTTATATTAAAAACAGATCTCATTTGATCCTTAA
GCCAGTCTCATGAATGAAAAGGACAGGTTTTTTTCTTTTGTAAATGAAGCATTTGCAGCTTAAAGAGGATGCATGAAATAACCCTTTTAT
CGCTTATAAATAGTGCCAGTTATGTGTTCCTGCCACGGCTGTGGAAATACTTCACATTTGCATTCCAGGACTGTTTTGGATCCATTTGCC
CGAGAATCTTCTGACTAACTCTGTGTCCTCATCTGGGCAGCACACACCAAGTGCCCACTGGTACCTCTGCATGTCCATGGTGCTGTGTGA
CTGGCCAGCCAGCAGCCAGTGACTCAGAGCTGGCTGTATGGAGGGGGTGGGAATGTTTCTGGAGATTTTTGTTTTTCCAGACACAGTCTT
GCTCAGTCCCCTAGGCTGGAGTGCAATGGCACCATCTCCGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCGGTTCTCCTGCCTCAGCC
TTCCAAGTAGCTGGGGTTATAGGCACCCACCACCATGCCGGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCTAG
GCTGGTCCCGAACTCCCGACTTCAAGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGATTTTTACTTGAGATT
TTTCCATCCTCTTTTAGGACTCAGGATAGACTTGTGTGGAGGTGCTCTCTGGCTAAGGGGATAAGTTGTTACTGGTTTGGGTCTGCTTGG
TTTTGCCTTGGGTGGGGCCGGTGTCGATGGGGCAGGCTTGGCACGAGCAGTGGTGCCATGGCAGGGCACTGTGGCATCTCCCCTAGCAGT
GGATTTGGGGTCCCTGCTTGCCTCACGTGGTGCTTACACACATGTACACACACACACACACACACACACACACACACACCTTACACACAT
GTACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACCCCTGTTCTGCAGGGC
TTCAGCGTGGCCTTCATTCCCGCCTCGCCTCGGCCTCTTTTCAATTAAGAAGTGATGCCACTTGAGGCAGGGTCTGCATGATCACTTCTT
GGGTTTCAGTTTGAAAGCTGCCATCCCTGCGACTGCCCAGGGCCTGTATGTTGGGACCGAAGCCAAACACCACTGTCCTCCAGGGGGCTT
TCGGCCCGGGGCAGGGTCCCCAGTGCCCGCCTTCGAATCAGACTCCGCGTTTCCGCCTCTCCCTGGGCGGACCTGCCGCTAGAGGGCGCT
CCTCCTCCGCAGCCGGCGCCGGCCTCCAGCGCCCCAGACTCCCGCGCTGCCGCCCGAGCCTGAGGTTTCTCACGGCGTTCGGGATTCGCG
CTTCGGAAACCGGGAACAAAGAAGCAAGCAGCACCCTTCAGAAACAGTGTTCTCGCTCTCCTAGCAGCTGGCCCGGGCCCGGAGGCTGGT
GCCAGGAGAAGGCAGAAGAGCCCGGGCAGCCGGAGTGGGCTACGGGGTTCAGGCAGTGCCAAGGAAGAAGGGCCTCACAATGGGCAATTC
AGCTGCCTCCCGGGCCGTTGTCCCCGCTGTCTTCAAACAGGGGTCCCCTGTCCCAGCTGCCCCAGGAGGAGGGGGGGAGGCAGGCAGGGC
CGAAACCCTCCAGAGCCCAGAGGGGGACGCTTGGTGGCCGCTGCAGTTACATAACCATAGGATGCTTTTGTACCGTGGACCTTGTTCTAG

>49672_49672_2_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000273261_BDH1_chr3_197260432_ENST00000392378_length(amino acids)=564AA_BP=249
MNACLPGAAAALPSAGVGSGTRRAPGGRRAQAGYTLPESAEFAASAGGPAGPDGRGVCGPRRVLRSGPGTGGTLSAGAAAAERTWGGGHA
PVRSLEPSGAPRGPARVCGRSGPHSPRARSSQRAPDKMARPVRGGLGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLD
CGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLRPLLLGSTSFIPIGRRTYASA
AEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMW
GLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPL
GVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMD

--------------------------------------------------------------
>49672_49672_3_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000273261_BDH1_chr3_197260432_ENST00000392379_length(transcript)=3951nt_BP=890nt
GCTCTCTGGCCGCGGCGTGGGGACAGCGAGGCGCACTGGGGCCTCCCAGCGCGGGGCCGGCCGCGCCGTCCAGCCCGAGGTCTACGGCTT
TGCGCTCCGAGCCCAGAGGAAGATGCCTGCCGGCACCGAGCTCGGGCTGCGGGGCTGAACGCCTGTCTTCCAGGCGCAGCGGCAGCACTG
CCCTCGGCCGGTGTCGGTAGCGGCACTCGGCGTGCCCCGGGCGGACGAAGAGCGCAGGCTGGGTACACCTTGCCCGAATCGGCGGAGTTC
GCAGCTAGCGCGGGCGGGCCGGCCGGCCCGGATGGGCGCGGGGTTTGCGGCCCCCGCCGGGTGCTCCGGAGCGGCCCGGGCACCGGGGGC
ACGCTGAGTGCCGGAGCCGCGGCCGCAGAGAGAACTTGGGGCGGGGGCCATGCCCCGGTGCGGAGTCTAGAGCCGAGCGGAGCGCCCCGC
GGGCCCGCCCGCGTCTGCGGCCGTTCGGGTCCTCACAGTCCCCGCGCCCGGAGTTCGCAGCGCGCTCCAGACAAGATGGCGCGGCCGGTC
CGGGGAGGGCTCGGGGCCCCGCGCCGCTCGCCTTGCCTTCTCCTTCTCTGGCTGCTTTTGCTTCGGCTGGAGCCGGTGACCGCCGCGGCC
GGCCCGCGGGCGCCCTGCGCGGCCGCCTGCACTTGCGCTGGGGACTCGCTGGACTGCGGTGGGCGCGGGCTGGCTGCGTTGCCCGGGGAC
CTGCCCTCCTGGACGCGGAGCCTAAACCTGAGTTACAACAAACTCTCTGAGATTGACCCTGCTGGTTTTGAGGACTTGCCGAACCTACAG
GAAGTGTACCTCAATAATAATGAGTTGACAGCGGTACCATCCCTGGGCGCTGCTTCATCACATGTCGTCTCTCTCTTTCTACGCCCACTA
TTGCTTGGTTCTACTTCCTTTATCCCGATTGGCCGTCGGACTTATGCCAGTGCGGCGGAGCCGGTTGGCAGCAAAGCTGTCCTGGTCACA
GGCTGTGACTCTGGATTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTCCTTGTGTTTGCTGGCTGCTTGATGAAGGACAAA
GGCCATGATGGGGTCAAGGAGCTGGACAGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAGCGAAGAGGTGGAG
AAAGTGGTGGAGATTGTCCGCTCGAGCCTGAAGGACCCTGAGAAAGGCATGTGGGGCCTCGTTAACAATGCCGGCATCTCAACGTTCGGG
GAGGTGGAGTTCACCAGCCTGGAGACCTACAAGCAGGTGGCAGAAGTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTCCCC
CTCATCCGAAGGGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCATGGCCAACCCGGCCCGCTCCCCGTACTGCATCACC
AAGTTCGGGGTAGAGGCTTTCTCGGACTGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGTCAGCGTGGTGGAGCCCGGCAACTTC
ATCGCTGCCACCAGCCTTTACAGCCCTGAGAGCATTCAGGCCATCGCCAAGAAGATGTGGGAGGAGCTGCCTGAGGTCGTGCGCAAGGAC
TACGGCAAGAAGTACTTTGATGAAAAGATCGCCAAGATGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCGATGCT
GTCACACACGCCCTGACCGCCACCACCCCCTACACCCGCTACCACCCCATGGACTACTACTGGTGGCTGCGAATGCAGATCATGACCCAC
TTGCCTGGAGCCATCTCCGACATGATCTACATCCGCTGAAGAGTCTCGCTGTGGCCTCTGTCAGGGATCCCTGGTGGAAGGGGAGGGGAG
GGAGGAACCCATATAGTCAACTCTTGATTATCCACGTGTGGATTATCCACCATGCCAGGAAGACCCATAACTGGTTTTAACACTAACTAG
AGGGAATGACTTCTTTGCATAGTGAGTGACTTGGGCCTTCACAAACAGGGTGTGGAGTGGCAGGCAGAGGCCTCTAAATCTCAGGGCAAA
CATGGTGAATCTATCTCTCCGGAGATAATTTCATACAGAGATTTTAAGAAAACATCTTTATATTAAAAACAGATCTCATTTGATCCTTAA
GCCAGTCTCATGAATGAAAAGGACAGGTTTTTTTCTTTTGTAAATGAAGCATTTGCAGCTTAAAGAGGATGCATGAAATAACCCTTTTAT
CGCTTATAAATAGTGCCAGTTATGTGTTCCTGCCACGGCTGTGGAAATACTTCACATTTGCATTCCAGGACTGTTTTGGATCCATTTGCC
CGAGAATCTTCTGACTAACTCTGTGTCCTCATCTGGGCAGCACACACCAAGTGCCCACTGGTACCTCTGCATGTCCATGGTGCTGTGTGA
CTGGCCAGCCAGCAGCCAGTGACTCAGAGCTGGCTGTATGGAGGGGGTGGGAATGTTTCTGGAGATTTTTGTTTTTCCAGACACAGTCTT
GCTCAGTCCCCTAGGCTGGAGTGCAATGGCACCATCTCCGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCGGTTCTCCTGCCTCAGCC
TTCCAAGTAGCTGGGGTTATAGGCACCCACCACCATGCCGGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCTAG
GCTGGTCCCGAACTCCCGACTTCAAGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGATTTTTACTTGAGATT
TTTCCATCCTCTTTTAGGACTCAGGATAGACTTGTGTGGAGGTGCTCTCTGGCTAAGGGGATAAGTTGTTACTGGTTTGGGTCTGCTTGG
TTTTGCCTTGGGTGGGGCCGGTGTCGATGGGGCAGGCTTGGCACGAGCAGTGGTGCCATGGCAGGGCACTGTGGCATCTCCCCTAGCAGT
GGATTTGGGGTCCCTGCTTGCCTCACGTGGTGCTTACACACATGTACACACACACACACACACACACACACACACACACCTTACACACAT
GTACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACCCCTGTTCTGCAGGGC
TTCAGCGTGGCCTTCATTCCCGCCTCGCCTCGGCCTCTTTTCAATTAAGAAGTGATGCCACTTGAGGCAGGGTCTGCATGATCACTTCTT
GGGTTTCAGTTTGAAAGCTGCCATCCCTGCGACTGCCCAGGGCCTGTATGTTGGGACCGAAGCCAAACACCACTGTCCTCCAGGGGGCTT
TCGGCCCGGGGCAGGGTCCCCAGTGCCCGCCTTCGAATCAGACTCCGCGTTTCCGCCTCTCCCTGGGCGGACCTGCCGCTAGAGGGCGCT
CCTCCTCCGCAGCCGGCGCCGGCCTCCAGCGCCCCAGACTCCCGCGCTGCCGCCCGAGCCTGAGGTTTCTCACGGCGTTCGGGATTCGCG
CTTCGGAAACCGGGAACAAAGAAGCAAGCAGCACCCTTCAGAAACAGTGTTCTCGCTCTCCTAGCAGCTGGCCCGGGCCCGGAGGCTGGT
GCCAGGAGAAGGCAGAAGAGCCCGGGCAGCCGGAGTGGGCTACGGGGTTCAGGCAGTGCCAAGGAAGAAGGGCCTCACAATGGGCAATTC
AGCTGCCTCCCGGGCCGTTGTCCCCGCTGTCTTCAAACAGGGGTCCCCTGTCCCAGCTGCCCCAGGAGGAGGGGGGGAGGCAGGCAGGGC
CGAAACCCTCCAGAGCCCAGAGGGGGACGCTTGGTGGCCGCTGCAGTTACATAACCATAGGATGCTTTTGTACCGTGGACCTTGTTCTAG

>49672_49672_3_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000273261_BDH1_chr3_197260432_ENST00000392379_length(amino acids)=564AA_BP=249
MNACLPGAAAALPSAGVGSGTRRAPGGRRAQAGYTLPESAEFAASAGGPAGPDGRGVCGPRRVLRSGPGTGGTLSAGAAAAERTWGGGHA
PVRSLEPSGAPRGPARVCGRSGPHSPRARSSQRAPDKMARPVRGGLGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLD
CGGRGLAALPGDLPSWTRSLNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLRPLLLGSTSFIPIGRRTYASA
AEPVGSKAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMW
GLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPL
GVKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMD

--------------------------------------------------------------
>49672_49672_4_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000383703_BDH1_chr3_197260432_ENST00000358186_length(transcript)=4030nt_BP=969nt
GATTGTTCGGCTGCGAGGTCGGCGGGACTCTTGCTGCGCGGAGGAGCCGTGCGGAACCCGAGGCTGCGCGCGCGCGCGCGCTCTCTGGCC
GCGGCGTGGGGACAGCGAGGCGCACTGGGGCCTCCCAGCGCGGGGCCGGCCGCGCCGTCCAGCCCGAGGTCTACGGCTTTGCGCTCCGAG
CCCAGAGGAAGATGCCTGCCGGCACCGAGCTCGGGCTGCGGGGCTGAACGCCTGTCTTCCAGGCGCAGCGGCAGCACTGCCCTCGGCCGG
TGTCGGTAGCGGCACTCGGCGTGCCCCGGGCGGACGAAGAGCGCAGGCTGGGTACACCTTGCCCGAATCGGCGGAGTTCGCAGCTAGCGC
GGGCGGGCCGGCCGGCCCGGATGGGCGCGGGGTTTGCGGCCCCCGCCGGGTGCTCCGGAGCGGCCCGGGCACCGGGGGCACGCTGAGTGC
CGGAGCCGCGGCCGCAGAGAGAACTTGGGGCGGGGGCCATGCCCCGGTGCGGAGTCTAGAGCCGAGCGGAGCGCCCCGCGGGCCCGCCCG
CGTCTGCGGCCGTTCGGGTCCTCACAGTCCCCGCGCCCGGAGTTCGCAGCGCGCTCCAGACAAGATGGCGCGGCCGGTCCGGGGAGGGCT
CGGGGCCCCGCGCCGCTCGCCTTGCCTTCTCCTTCTCTGGCTGCTTTTGCTTCGGCTGGAGCCGGTGACCGCCGCGGCCGGCCCGCGGGC
GCCCTGCGCGGCCGCCTGCACTTGCGCTGGGGACTCGCTGGACTGCGGTGGGCGCGGGCTGGCTGCGTTGCCCGGGGACCTGCCCTCCTG
GACGCGGAGCCTAAACCTGAGTTACAACAAACTCTCTGAGATTGACCCTGCTGGTTTTGAGGACTTGCCGAACCTACAGGAAGTGTACCT
CAATAATAATGAGTTGACAGCGGTACCATCCCTGGGCGCTGCTTCATCACATGTCGTCTCTCTCTTTCTACGCCCACTATTGCTTGGTTC
TACTTCCTTTATCCCGATTGGCCGTCGGACTTATGCCAGTGCGGCGGAGCCGGTTGGCAGCAAAGCTGTCCTGGTCACAGGCTGTGACTC
TGGATTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTCCTTGTGTTTGCTGGCTGCTTGATGAAGGACAAAGGCCATGATGG
GGTCAAGGAGCTGGACAGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAGCGAAGAGGTGGAGAAAGTGGTGGA
GATTGTCCGCTCGAGCCTGAAGGACCCTGAGAAAGGCATGTGGGGCCTCGTTAACAATGCCGGCATCTCAACGTTCGGGGAGGTGGAGTT
CACCAGCCTGGAGACCTACAAGCAGGTGGCAGAAGTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTCCCCCTCATCCGAAG
GGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCATGGCCAACCCGGCCCGCTCCCCGTACTGCATCACCAAGTTCGGGGT
AGAGGCTTTCTCGGACTGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGTCAGCGTGGTGGAGCCCGGCAACTTCATCGCTGCCAC
CAGCCTTTACAGCCCTGAGAGCATTCAGGCCATCGCCAAGAAGATGTGGGAGGAGCTGCCTGAGGTCGTGCGCAAGGACTACGGCAAGAA
GTACTTTGATGAAAAGATCGCCAAGATGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCGATGCTGTCACACACGC
CCTGACCGCCACCACCCCCTACACCCGCTACCACCCCATGGACTACTACTGGTGGCTGCGAATGCAGATCATGACCCACTTGCCTGGAGC
CATCTCCGACATGATCTACATCCGCTGAAGAGTCTCGCTGTGGCCTCTGTCAGGGATCCCTGGTGGAAGGGGAGGGGAGGGAGGAACCCA
TATAGTCAACTCTTGATTATCCACGTGTGGATTATCCACCATGCCAGGAAGACCCATAACTGGTTTTAACACTAACTAGAGGGAATGACT
TCTTTGCATAGTGAGTGACTTGGGCCTTCACAAACAGGGTGTGGAGTGGCAGGCAGAGGCCTCTAAATCTCAGGGCAAACATGGTGAATC
TATCTCTCCGGAGATAATTTCATACAGAGATTTTAAGAAAACATCTTTATATTAAAAACAGATCTCATTTGATCCTTAAGCCAGTCTCAT
GAATGAAAAGGACAGGTTTTTTTCTTTTGTAAATGAAGCATTTGCAGCTTAAAGAGGATGCATGAAATAACCCTTTTATCGCTTATAAAT
AGTGCCAGTTATGTGTTCCTGCCACGGCTGTGGAAATACTTCACATTTGCATTCCAGGACTGTTTTGGATCCATTTGCCCGAGAATCTTC
TGACTAACTCTGTGTCCTCATCTGGGCAGCACACACCAAGTGCCCACTGGTACCTCTGCATGTCCATGGTGCTGTGTGACTGGCCAGCCA
GCAGCCAGTGACTCAGAGCTGGCTGTATGGAGGGGGTGGGAATGTTTCTGGAGATTTTTGTTTTTCCAGACACAGTCTTGCTCAGTCCCC
TAGGCTGGAGTGCAATGGCACCATCTCCGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCGGTTCTCCTGCCTCAGCCTTCCAAGTAGC
TGGGGTTATAGGCACCCACCACCATGCCGGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCTAGGCTGGTCCCGA
ACTCCCGACTTCAAGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGATTTTTACTTGAGATTTTTCCATCCTC
TTTTAGGACTCAGGATAGACTTGTGTGGAGGTGCTCTCTGGCTAAGGGGATAAGTTGTTACTGGTTTGGGTCTGCTTGGTTTTGCCTTGG
GTGGGGCCGGTGTCGATGGGGCAGGCTTGGCACGAGCAGTGGTGCCATGGCAGGGCACTGTGGCATCTCCCCTAGCAGTGGATTTGGGGT
CCCTGCTTGCCTCACGTGGTGCTTACACACATGTACACACACACACACACACACACACACACACACACCTTACACACATGTACACACACA
CACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACCCCTGTTCTGCAGGGCTTCAGCGTGGC
CTTCATTCCCGCCTCGCCTCGGCCTCTTTTCAATTAAGAAGTGATGCCACTTGAGGCAGGGTCTGCATGATCACTTCTTGGGTTTCAGTT
TGAAAGCTGCCATCCCTGCGACTGCCCAGGGCCTGTATGTTGGGACCGAAGCCAAACACCACTGTCCTCCAGGGGGCTTTCGGCCCGGGG
CAGGGTCCCCAGTGCCCGCCTTCGAATCAGACTCCGCGTTTCCGCCTCTCCCTGGGCGGACCTGCCGCTAGAGGGCGCTCCTCCTCCGCA
GCCGGCGCCGGCCTCCAGCGCCCCAGACTCCCGCGCTGCCGCCCGAGCCTGAGGTTTCTCACGGCGTTCGGGATTCGCGCTTCGGAAACC
GGGAACAAAGAAGCAAGCAGCACCCTTCAGAAACAGTGTTCTCGCTCTCCTAGCAGCTGGCCCGGGCCCGGAGGCTGGTGCCAGGAGAAG
GCAGAAGAGCCCGGGCAGCCGGAGTGGGCTACGGGGTTCAGGCAGTGCCAAGGAAGAAGGGCCTCACAATGGGCAATTCAGCTGCCTCCC
GGGCCGTTGTCCCCGCTGTCTTCAAACAGGGGTCCCCTGTCCCAGCTGCCCCAGGAGGAGGGGGGGAGGCAGGCAGGGCCGAAACCCTCC
AGAGCCCAGAGGGGGACGCTTGGTGGCCGCTGCAGTTACATAACCATAGGATGCTTTTGTACCGTGGACCTTGTTCTAGCAGGATCCTTT

>49672_49672_4_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000383703_BDH1_chr3_197260432_ENST00000358186_length(amino acids)=635AA_BP=320
MRGRRDSCCAEEPCGTRGCARARALWPRRGDSEAHWGLPARGRPRRPARGLRLCAPSPEEDACRHRARAAGLNACLPGAAAALPSAGVGS
GTRRAPGGRRAQAGYTLPESAEFAASAGGPAGPDGRGVCGPRRVLRSGPGTGGTLSAGAAAAERTWGGGHAPVRSLEPSGAPRGPARVCG
RSGPHSPRARSSQRAPDKMARPVRGGLGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLDCGGRGLAALPGDLPSWTRS
LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFG
FSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSL
ETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLY
SPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISD

--------------------------------------------------------------
>49672_49672_5_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000383703_BDH1_chr3_197260432_ENST00000392378_length(transcript)=4030nt_BP=969nt
GATTGTTCGGCTGCGAGGTCGGCGGGACTCTTGCTGCGCGGAGGAGCCGTGCGGAACCCGAGGCTGCGCGCGCGCGCGCGCTCTCTGGCC
GCGGCGTGGGGACAGCGAGGCGCACTGGGGCCTCCCAGCGCGGGGCCGGCCGCGCCGTCCAGCCCGAGGTCTACGGCTTTGCGCTCCGAG
CCCAGAGGAAGATGCCTGCCGGCACCGAGCTCGGGCTGCGGGGCTGAACGCCTGTCTTCCAGGCGCAGCGGCAGCACTGCCCTCGGCCGG
TGTCGGTAGCGGCACTCGGCGTGCCCCGGGCGGACGAAGAGCGCAGGCTGGGTACACCTTGCCCGAATCGGCGGAGTTCGCAGCTAGCGC
GGGCGGGCCGGCCGGCCCGGATGGGCGCGGGGTTTGCGGCCCCCGCCGGGTGCTCCGGAGCGGCCCGGGCACCGGGGGCACGCTGAGTGC
CGGAGCCGCGGCCGCAGAGAGAACTTGGGGCGGGGGCCATGCCCCGGTGCGGAGTCTAGAGCCGAGCGGAGCGCCCCGCGGGCCCGCCCG
CGTCTGCGGCCGTTCGGGTCCTCACAGTCCCCGCGCCCGGAGTTCGCAGCGCGCTCCAGACAAGATGGCGCGGCCGGTCCGGGGAGGGCT
CGGGGCCCCGCGCCGCTCGCCTTGCCTTCTCCTTCTCTGGCTGCTTTTGCTTCGGCTGGAGCCGGTGACCGCCGCGGCCGGCCCGCGGGC
GCCCTGCGCGGCCGCCTGCACTTGCGCTGGGGACTCGCTGGACTGCGGTGGGCGCGGGCTGGCTGCGTTGCCCGGGGACCTGCCCTCCTG
GACGCGGAGCCTAAACCTGAGTTACAACAAACTCTCTGAGATTGACCCTGCTGGTTTTGAGGACTTGCCGAACCTACAGGAAGTGTACCT
CAATAATAATGAGTTGACAGCGGTACCATCCCTGGGCGCTGCTTCATCACATGTCGTCTCTCTCTTTCTACGCCCACTATTGCTTGGTTC
TACTTCCTTTATCCCGATTGGCCGTCGGACTTATGCCAGTGCGGCGGAGCCGGTTGGCAGCAAAGCTGTCCTGGTCACAGGCTGTGACTC
TGGATTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTCCTTGTGTTTGCTGGCTGCTTGATGAAGGACAAAGGCCATGATGG
GGTCAAGGAGCTGGACAGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAGCGAAGAGGTGGAGAAAGTGGTGGA
GATTGTCCGCTCGAGCCTGAAGGACCCTGAGAAAGGCATGTGGGGCCTCGTTAACAATGCCGGCATCTCAACGTTCGGGGAGGTGGAGTT
CACCAGCCTGGAGACCTACAAGCAGGTGGCAGAAGTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTCCCCCTCATCCGAAG
GGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCATGGCCAACCCGGCCCGCTCCCCGTACTGCATCACCAAGTTCGGGGT
AGAGGCTTTCTCGGACTGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGTCAGCGTGGTGGAGCCCGGCAACTTCATCGCTGCCAC
CAGCCTTTACAGCCCTGAGAGCATTCAGGCCATCGCCAAGAAGATGTGGGAGGAGCTGCCTGAGGTCGTGCGCAAGGACTACGGCAAGAA
GTACTTTGATGAAAAGATCGCCAAGATGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCGATGCTGTCACACACGC
CCTGACCGCCACCACCCCCTACACCCGCTACCACCCCATGGACTACTACTGGTGGCTGCGAATGCAGATCATGACCCACTTGCCTGGAGC
CATCTCCGACATGATCTACATCCGCTGAAGAGTCTCGCTGTGGCCTCTGTCAGGGATCCCTGGTGGAAGGGGAGGGGAGGGAGGAACCCA
TATAGTCAACTCTTGATTATCCACGTGTGGATTATCCACCATGCCAGGAAGACCCATAACTGGTTTTAACACTAACTAGAGGGAATGACT
TCTTTGCATAGTGAGTGACTTGGGCCTTCACAAACAGGGTGTGGAGTGGCAGGCAGAGGCCTCTAAATCTCAGGGCAAACATGGTGAATC
TATCTCTCCGGAGATAATTTCATACAGAGATTTTAAGAAAACATCTTTATATTAAAAACAGATCTCATTTGATCCTTAAGCCAGTCTCAT
GAATGAAAAGGACAGGTTTTTTTCTTTTGTAAATGAAGCATTTGCAGCTTAAAGAGGATGCATGAAATAACCCTTTTATCGCTTATAAAT
AGTGCCAGTTATGTGTTCCTGCCACGGCTGTGGAAATACTTCACATTTGCATTCCAGGACTGTTTTGGATCCATTTGCCCGAGAATCTTC
TGACTAACTCTGTGTCCTCATCTGGGCAGCACACACCAAGTGCCCACTGGTACCTCTGCATGTCCATGGTGCTGTGTGACTGGCCAGCCA
GCAGCCAGTGACTCAGAGCTGGCTGTATGGAGGGGGTGGGAATGTTTCTGGAGATTTTTGTTTTTCCAGACACAGTCTTGCTCAGTCCCC
TAGGCTGGAGTGCAATGGCACCATCTCCGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCGGTTCTCCTGCCTCAGCCTTCCAAGTAGC
TGGGGTTATAGGCACCCACCACCATGCCGGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCTAGGCTGGTCCCGA
ACTCCCGACTTCAAGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGATTTTTACTTGAGATTTTTCCATCCTC
TTTTAGGACTCAGGATAGACTTGTGTGGAGGTGCTCTCTGGCTAAGGGGATAAGTTGTTACTGGTTTGGGTCTGCTTGGTTTTGCCTTGG
GTGGGGCCGGTGTCGATGGGGCAGGCTTGGCACGAGCAGTGGTGCCATGGCAGGGCACTGTGGCATCTCCCCTAGCAGTGGATTTGGGGT
CCCTGCTTGCCTCACGTGGTGCTTACACACATGTACACACACACACACACACACACACACACACACACCTTACACACATGTACACACACA
CACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACCCCTGTTCTGCAGGGCTTCAGCGTGGC
CTTCATTCCCGCCTCGCCTCGGCCTCTTTTCAATTAAGAAGTGATGCCACTTGAGGCAGGGTCTGCATGATCACTTCTTGGGTTTCAGTT
TGAAAGCTGCCATCCCTGCGACTGCCCAGGGCCTGTATGTTGGGACCGAAGCCAAACACCACTGTCCTCCAGGGGGCTTTCGGCCCGGGG
CAGGGTCCCCAGTGCCCGCCTTCGAATCAGACTCCGCGTTTCCGCCTCTCCCTGGGCGGACCTGCCGCTAGAGGGCGCTCCTCCTCCGCA
GCCGGCGCCGGCCTCCAGCGCCCCAGACTCCCGCGCTGCCGCCCGAGCCTGAGGTTTCTCACGGCGTTCGGGATTCGCGCTTCGGAAACC
GGGAACAAAGAAGCAAGCAGCACCCTTCAGAAACAGTGTTCTCGCTCTCCTAGCAGCTGGCCCGGGCCCGGAGGCTGGTGCCAGGAGAAG
GCAGAAGAGCCCGGGCAGCCGGAGTGGGCTACGGGGTTCAGGCAGTGCCAAGGAAGAAGGGCCTCACAATGGGCAATTCAGCTGCCTCCC
GGGCCGTTGTCCCCGCTGTCTTCAAACAGGGGTCCCCTGTCCCAGCTGCCCCAGGAGGAGGGGGGGAGGCAGGCAGGGCCGAAACCCTCC
AGAGCCCAGAGGGGGACGCTTGGTGGCCGCTGCAGTTACATAACCATAGGATGCTTTTGTACCGTGGACCTTGTTCTAGCAGGATCCTTT

>49672_49672_5_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000383703_BDH1_chr3_197260432_ENST00000392378_length(amino acids)=635AA_BP=320
MRGRRDSCCAEEPCGTRGCARARALWPRRGDSEAHWGLPARGRPRRPARGLRLCAPSPEEDACRHRARAAGLNACLPGAAAALPSAGVGS
GTRRAPGGRRAQAGYTLPESAEFAASAGGPAGPDGRGVCGPRRVLRSGPGTGGTLSAGAAAAERTWGGGHAPVRSLEPSGAPRGPARVCG
RSGPHSPRARSSQRAPDKMARPVRGGLGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLDCGGRGLAALPGDLPSWTRS
LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFG
FSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSL
ETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLY
SPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISD

--------------------------------------------------------------
>49672_49672_6_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000383703_BDH1_chr3_197260432_ENST00000392379_length(transcript)=4030nt_BP=969nt
GATTGTTCGGCTGCGAGGTCGGCGGGACTCTTGCTGCGCGGAGGAGCCGTGCGGAACCCGAGGCTGCGCGCGCGCGCGCGCTCTCTGGCC
GCGGCGTGGGGACAGCGAGGCGCACTGGGGCCTCCCAGCGCGGGGCCGGCCGCGCCGTCCAGCCCGAGGTCTACGGCTTTGCGCTCCGAG
CCCAGAGGAAGATGCCTGCCGGCACCGAGCTCGGGCTGCGGGGCTGAACGCCTGTCTTCCAGGCGCAGCGGCAGCACTGCCCTCGGCCGG
TGTCGGTAGCGGCACTCGGCGTGCCCCGGGCGGACGAAGAGCGCAGGCTGGGTACACCTTGCCCGAATCGGCGGAGTTCGCAGCTAGCGC
GGGCGGGCCGGCCGGCCCGGATGGGCGCGGGGTTTGCGGCCCCCGCCGGGTGCTCCGGAGCGGCCCGGGCACCGGGGGCACGCTGAGTGC
CGGAGCCGCGGCCGCAGAGAGAACTTGGGGCGGGGGCCATGCCCCGGTGCGGAGTCTAGAGCCGAGCGGAGCGCCCCGCGGGCCCGCCCG
CGTCTGCGGCCGTTCGGGTCCTCACAGTCCCCGCGCCCGGAGTTCGCAGCGCGCTCCAGACAAGATGGCGCGGCCGGTCCGGGGAGGGCT
CGGGGCCCCGCGCCGCTCGCCTTGCCTTCTCCTTCTCTGGCTGCTTTTGCTTCGGCTGGAGCCGGTGACCGCCGCGGCCGGCCCGCGGGC
GCCCTGCGCGGCCGCCTGCACTTGCGCTGGGGACTCGCTGGACTGCGGTGGGCGCGGGCTGGCTGCGTTGCCCGGGGACCTGCCCTCCTG
GACGCGGAGCCTAAACCTGAGTTACAACAAACTCTCTGAGATTGACCCTGCTGGTTTTGAGGACTTGCCGAACCTACAGGAAGTGTACCT
CAATAATAATGAGTTGACAGCGGTACCATCCCTGGGCGCTGCTTCATCACATGTCGTCTCTCTCTTTCTACGCCCACTATTGCTTGGTTC
TACTTCCTTTATCCCGATTGGCCGTCGGACTTATGCCAGTGCGGCGGAGCCGGTTGGCAGCAAAGCTGTCCTGGTCACAGGCTGTGACTC
TGGATTTGGGTTCTCATTGGCCAAGCATCTGCATTCAAAAGGCTTCCTTGTGTTTGCTGGCTGCTTGATGAAGGACAAAGGCCATGATGG
GGTCAAGGAGCTGGACAGCCTAAACAGTGACCGATTGAGAACCGTCCAGCTCAATGTCTGCAGCAGCGAAGAGGTGGAGAAAGTGGTGGA
GATTGTCCGCTCGAGCCTGAAGGACCCTGAGAAAGGCATGTGGGGCCTCGTTAACAATGCCGGCATCTCAACGTTCGGGGAGGTGGAGTT
CACCAGCCTGGAGACCTACAAGCAGGTGGCAGAAGTGAACCTTTGGGGCACAGTGCGGATGACGAAATCCTTTCTCCCCCTCATCCGAAG
GGCCAAAGGCCGCGTCGTCAATATCAGCAGCATGCTGGGCCGCATGGCCAACCCGGCCCGCTCCCCGTACTGCATCACCAAGTTCGGGGT
AGAGGCTTTCTCGGACTGCCTGCGCTATGAGATGTACCCCCTGGGCGTGAAGGTCAGCGTGGTGGAGCCCGGCAACTTCATCGCTGCCAC
CAGCCTTTACAGCCCTGAGAGCATTCAGGCCATCGCCAAGAAGATGTGGGAGGAGCTGCCTGAGGTCGTGCGCAAGGACTACGGCAAGAA
GTACTTTGATGAAAAGATCGCCAAGATGGAGACCTACTGCAGCAGTGGCTCCACAGACACGTCCCCTGTCATCGATGCTGTCACACACGC
CCTGACCGCCACCACCCCCTACACCCGCTACCACCCCATGGACTACTACTGGTGGCTGCGAATGCAGATCATGACCCACTTGCCTGGAGC
CATCTCCGACATGATCTACATCCGCTGAAGAGTCTCGCTGTGGCCTCTGTCAGGGATCCCTGGTGGAAGGGGAGGGGAGGGAGGAACCCA
TATAGTCAACTCTTGATTATCCACGTGTGGATTATCCACCATGCCAGGAAGACCCATAACTGGTTTTAACACTAACTAGAGGGAATGACT
TCTTTGCATAGTGAGTGACTTGGGCCTTCACAAACAGGGTGTGGAGTGGCAGGCAGAGGCCTCTAAATCTCAGGGCAAACATGGTGAATC
TATCTCTCCGGAGATAATTTCATACAGAGATTTTAAGAAAACATCTTTATATTAAAAACAGATCTCATTTGATCCTTAAGCCAGTCTCAT
GAATGAAAAGGACAGGTTTTTTTCTTTTGTAAATGAAGCATTTGCAGCTTAAAGAGGATGCATGAAATAACCCTTTTATCGCTTATAAAT
AGTGCCAGTTATGTGTTCCTGCCACGGCTGTGGAAATACTTCACATTTGCATTCCAGGACTGTTTTGGATCCATTTGCCCGAGAATCTTC
TGACTAACTCTGTGTCCTCATCTGGGCAGCACACACCAAGTGCCCACTGGTACCTCTGCATGTCCATGGTGCTGTGTGACTGGCCAGCCA
GCAGCCAGTGACTCAGAGCTGGCTGTATGGAGGGGGTGGGAATGTTTCTGGAGATTTTTGTTTTTCCAGACACAGTCTTGCTCAGTCCCC
TAGGCTGGAGTGCAATGGCACCATCTCCGCTCACTGCAACCTCCGCCTCCCTGGTTCAAGCGGTTCTCCTGCCTCAGCCTTCCAAGTAGC
TGGGGTTATAGGCACCCACCACCATGCCGGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTCACCATGTTGGCTAGGCTGGTCCCGA
ACTCCCGACTTCAAGTGATCCGCCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGATTTTTACTTGAGATTTTTCCATCCTC
TTTTAGGACTCAGGATAGACTTGTGTGGAGGTGCTCTCTGGCTAAGGGGATAAGTTGTTACTGGTTTGGGTCTGCTTGGTTTTGCCTTGG
GTGGGGCCGGTGTCGATGGGGCAGGCTTGGCACGAGCAGTGGTGCCATGGCAGGGCACTGTGGCATCTCCCCTAGCAGTGGATTTGGGGT
CCCTGCTTGCCTCACGTGGTGCTTACACACATGTACACACACACACACACACACACACACACACACACCTTACACACATGTACACACACA
CACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACACCCCTGTTCTGCAGGGCTTCAGCGTGGC
CTTCATTCCCGCCTCGCCTCGGCCTCTTTTCAATTAAGAAGTGATGCCACTTGAGGCAGGGTCTGCATGATCACTTCTTGGGTTTCAGTT
TGAAAGCTGCCATCCCTGCGACTGCCCAGGGCCTGTATGTTGGGACCGAAGCCAAACACCACTGTCCTCCAGGGGGCTTTCGGCCCGGGG
CAGGGTCCCCAGTGCCCGCCTTCGAATCAGACTCCGCGTTTCCGCCTCTCCCTGGGCGGACCTGCCGCTAGAGGGCGCTCCTCCTCCGCA
GCCGGCGCCGGCCTCCAGCGCCCCAGACTCCCGCGCTGCCGCCCGAGCCTGAGGTTTCTCACGGCGTTCGGGATTCGCGCTTCGGAAACC
GGGAACAAAGAAGCAAGCAGCACCCTTCAGAAACAGTGTTCTCGCTCTCCTAGCAGCTGGCCCGGGCCCGGAGGCTGGTGCCAGGAGAAG
GCAGAAGAGCCCGGGCAGCCGGAGTGGGCTACGGGGTTCAGGCAGTGCCAAGGAAGAAGGGCCTCACAATGGGCAATTCAGCTGCCTCCC
GGGCCGTTGTCCCCGCTGTCTTCAAACAGGGGTCCCCTGTCCCAGCTGCCCCAGGAGGAGGGGGGGAGGCAGGCAGGGCCGAAACCCTCC
AGAGCCCAGAGGGGGACGCTTGGTGGCCGCTGCAGTTACATAACCATAGGATGCTTTTGTACCGTGGACCTTGTTCTAGCAGGATCCTTT

>49672_49672_6_LRIG1-BDH1_LRIG1_chr3_66501983_ENST00000383703_BDH1_chr3_197260432_ENST00000392379_length(amino acids)=635AA_BP=320
MRGRRDSCCAEEPCGTRGCARARALWPRRGDSEAHWGLPARGRPRRPARGLRLCAPSPEEDACRHRARAAGLNACLPGAAAALPSAGVGS
GTRRAPGGRRAQAGYTLPESAEFAASAGGPAGPDGRGVCGPRRVLRSGPGTGGTLSAGAAAAERTWGGGHAPVRSLEPSGAPRGPARVCG
RSGPHSPRARSSQRAPDKMARPVRGGLGAPRRSPCLLLLWLLLLRLEPVTAAAGPRAPCAAACTCAGDSLDCGGRGLAALPGDLPSWTRS
LNLSYNKLSEIDPAGFEDLPNLQEVYLNNNELTAVPSLGAASSHVVSLFLRPLLLGSTSFIPIGRRTYASAAEPVGSKAVLVTGCDSGFG
FSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSL
ETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPGNFIAATSLY
SPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAKMETYCSSGSTDTSPVIDAVTHALTATTPYTRYHPMDYYWWLRMQIMTHLPGAISD

--------------------------------------------------------------

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Fusion Gene PPI Analysis for LRIG1-BDH1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for LRIG1-BDH1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for LRIG1-BDH1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource