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Center for Computational Systems Medicine
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Fusion Gene Summary

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Fusion Gene ORF analysis

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Fusion Genomic Features

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Fusion Protein Features

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Fusion Gene Sequence

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Fusion Gene PPI analysis

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Related Drugs

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Related Diseases

Fusion gene:ANP32B-PRKG1 (FusionGDB2 ID:4972)

Fusion Gene Summary for ANP32B-PRKG1

check button Fusion gene summary
Fusion gene informationFusion gene name: ANP32B-PRKG1
Fusion gene ID: 4972
HgeneTgene
Gene symbol

ANP32B

PRKG1

Gene ID

10541

5592

Gene nameacidic nuclear phosphoprotein 32 family member Bprotein kinase cGMP-dependent 1
SynonymsAPRIL|PHAPI2|SSP29AAT8|PKG|PKG1|PRKG1B|PRKGR1B|cGK|cGK 1|cGK1|cGKI|cGKI-BETA|cGKI-alpha
Cytomap

9q22.33

10q11.23-q21.1

Type of geneprotein-codingprotein-coding
Descriptionacidic leucine-rich nuclear phosphoprotein 32 family member Bacidic (leucine-rich) nuclear phosphoprotein 32 family, member Bacidic protein rich in leucinesputative HLA-DR-associated protein I-2silver-stainable protein SSP29cGMP-dependent protein kinase 1protein kinase, cGMP-dependent, regulatory, type I, betaprotein kinase, cGMP-dependent, type I
Modification date2020031320200322
UniProtAcc

Q92688

.
Ensembl transtripts involved in fusion geneENST00000339399, ENST00000473205, 
ENST00000373975, ENST00000373980, 
ENST00000373985, ENST00000401604, 
Fusion gene scores* DoF score12 X 13 X 4=62414 X 13 X 6=1092
# samples 1314
** MAII scorelog2(13/624*10)=-2.26303440583379
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0		log2(14/1092*10)=-2.96347412397489
possibly effective Gene in Pan-Cancer Fusion Genes (peGinPCFGs).
DoF>8 and MAII<0
Context

PubMed: ANP32B [Title/Abstract] AND PRKG1 [Title/Abstract] AND fusion [Title/Abstract]

Most frequent breakpointANP32B(100745891)-PRKG1(53814244), # samples:1
Anticipated loss of major functional domain due to fusion event.
* DoF score (Degree of Frequency) = # partners X # break points X # cancer types
** MAII score (Major Active Isofusion Index) = log2(# samples/DoF score*10)

check button Gene ontology of each fusion partner gene with evidence of Inferred from Direct Assay (IDA) from Entrez
PartnerGeneGO IDGO termPubMed ID
HgeneANP32B

GO:0006334

nucleosome assembly

20538007

HgeneANP32B

GO:0045596

negative regulation of cell differentiation

22705300

TgenePRKG1

GO:0006468

protein phosphorylation

15905169

TgenePRKG1

GO:1904706

negative regulation of vascular smooth muscle cell proliferation

25447536

TgenePRKG1

GO:1904753

negative regulation of vascular associated smooth muscle cell migration

25447536


check buttonFusion gene breakpoints across ANP32B (5'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check buttonFusion gene breakpoints across PRKG1 (3'-gene)
* Click on the image to open the UCSC genome browser with custom track showing this image in a new window.
all structure

check button Fusion gene information from two resources (ChiTars 5.0 and ChimerDB 4.0)
* All genome coordinats were lifted-over on hg19.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
SourceDiseaseSampleHgeneHchrHbpHstrandTgeneTchrTbpTstrand
ChimerDB4OVTCGA-13-0720-01AANP32Bchr9

100745891

+PRKG1chr10

53814244

+


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Fusion Gene ORF analysis for ANP32B-PRKG1

check button Open reading frame (ORF) analsis of fusion genes based on Ensembl gene isoform structure.
* Click on the break point to see the gene structure around the break point region using the UCSC Genome Browser.
ORFHenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrand
5CDS-5UTRENST00000339399ENST00000373975ANP32Bchr9

100745891

+PRKG1chr10

53814244

+
In-frameENST00000339399ENST00000373980ANP32Bchr9

100745891

+PRKG1chr10

53814244

+
In-frameENST00000339399ENST00000373985ANP32Bchr9

100745891

+PRKG1chr10

53814244

+
In-frameENST00000339399ENST00000401604ANP32Bchr9

100745891

+PRKG1chr10

53814244

+
intron-3CDSENST00000473205ENST00000373980ANP32Bchr9

100745891

+PRKG1chr10

53814244

+
intron-3CDSENST00000473205ENST00000373985ANP32Bchr9

100745891

+PRKG1chr10

53814244

+
intron-3CDSENST00000473205ENST00000401604ANP32Bchr9

100745891

+PRKG1chr10

53814244

+
intron-5UTRENST00000473205ENST00000373975ANP32Bchr9

100745891

+PRKG1chr10

53814244

+

check buttonORFfinder result based on the fusion transcript sequence of in-frame fusion genes.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandSeq length
(transcript)		BP loci
(transcript)		Predicted start
(transcript)		Predicted stop
(transcript)		Seq length
(amino acids)
ENST00000339399ANP32Bchr9100745891+ENST00000401604PRKG1chr1053814244+3162249421547501
ENST00000339399ANP32Bchr9100745891+ENST00000373985PRKG1chr1053814244+5998249421547501
ENST00000339399ANP32Bchr9100745891+ENST00000373980PRKG1chr1053814244+5998249421547501

check buttonDeepORF prediction of the coding potential based on the fusion transcript sequence of in-frame fusion genes. DeepORF is a coding potential classifier based on convolutional neural network by comparing the real Ribo-seq data. If the no-coding score < 0.5 and coding score > 0.5, then the in-frame fusion transcript is predicted as being likely translated.
HenstTenstHgeneHchrHbpHstrandTgeneTchrTbpTstrandNo-coding scoreCoding score
ENST00000339399ENST00000401604ANP32Bchr9100745891+PRKG1chr1053814244+0.0004307130.99956924
ENST00000339399ENST00000373985ANP32Bchr9100745891+PRKG1chr1053814244+0.0001407330.9998592
ENST00000339399ENST00000373980ANP32Bchr9100745891+PRKG1chr1053814244+0.0001407330.9998592

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Fusion Genomic Features for ANP32B-PRKG1


check buttonFusionAI prediction of the potential fusion gene breakpoint based on the pre-mature RNA sequence context (+/- 5kb of individual partner genes, total 20kb length sequence). FusionAI is a fusion gene breakpoint classifier based on convolutional neural network by comparing the fusion positive and negative sequence context of ~ 20K fusion gene data. From here, we can have the relative potentency of the 20K genomic sequence how individual sequnce will be likely used as the gene fusion breakpoints.
HgeneHchrHbpHstrandTgeneTchrTbpTstrand1-pp (fusion gene breakpoint)
ANP32Bchr9100745891+PRKG1chr1053814243+0.882157740.11784227
ANP32Bchr9100745891+PRKG1chr1053814243+0.882157740.11784227

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions. We integrated a total of 44 different types of human genomic feature loci information across five big categories including virus integration sites, repeats, structural variants, chromatin states, and gene expression regulation. More details are in help page.
genomic feature

check buttonDistribution of 44 human genomic features loci across 20kb length fusion breakpoint regions that are ovelapped with the top 1% feature importance score regions. More details are in help page.
genomic feature of top 1%

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Fusion Protein Features for ANP32B-PRKG1


check button Four levels of functional features of fusion genes
Go to FGviewer search page for the most frequent breakpoint (https://ccsmweb.uth.edu/FGviewer/chr9:100745891/chr10:53814244)
- FGviewer provides the online visualization of the retention search of the protein functional features across DNA, RNA, protein, and pathological levels.
- How to search
1. Put your fusion gene symbol.
2. Press the tab key until there will be shown the breakpoint information filled.
4. Go down and press 'Search' tab twice.
4. Go down to have the hyperlink of the search result.
5. Click the hyperlink.
6. See the FGviewer result for your fusion gene.
FGviewer

check buttonMain function of each fusion partner protein. (from UniProt)
HgeneTgene
ANP32B

Q92688

.
FUNCTION: Multifunctional protein that is involved in the regulation of many processes including cell proliferation, apoptosis, cell cycle progression or transcription (PubMed:20015864, PubMed:18039846). Regulates the proliferation of neuronal stem cells, differentiation of leukemic cells and progression from G1 to S phase of the cell cycle. As negative regulator of caspase-3-dependent apoptosis, may act as an antagonist of ANP32A in regulating tissue homeostasis (PubMed:20015864). Exhibits histone chaperone properties, able to recruit histones to certain promoters, thus regulating the transcription of specific genes (PubMed:20538007, PubMed:18039846). Plays also an essential role in the nucleocytoplasmic transport of specific mRNAs via the uncommon nuclear mRNA export receptor XPO1/CRM1 (PubMed:17178712). Participates in the regulation of adequate adaptive immune responses by acting on mRNA expression and cell proliferation (By similarity). {ECO:0000250|UniProtKB:Q9EST5, ECO:0000269|PubMed:17178712, ECO:0000269|PubMed:18039846, ECO:0000269|PubMed:20015864, ECO:0000269|PubMed:20538007}.; FUNCTION: (Microbial infection) Plays an essential role in influenza A and B viral genome replication (PubMed:33045004, PubMed:31217244). Plays also a role in foamy virus mRNA export from the nucleus to the cytoplasm (PubMed:21159877). {ECO:0000269|PubMed:21159877, ECO:0000269|PubMed:31217244, ECO:0000269|PubMed:33045004}.FUNCTION: Transcriptional activator which is required for calcium-dependent dendritic growth and branching in cortical neurons. Recruits CREB-binding protein (CREBBP) to nuclear bodies. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an activator complex. In resting neurons, transcription of the c-FOS promoter is inhibited by BRG1-dependent recruitment of a phospho-RB1-HDAC1 repressor complex. Upon calcium influx, RB1 is dephosphorylated by calcineurin, which leads to release of the repressor complex. At the same time, there is increased recruitment of CREBBP to the promoter by a CREST-dependent mechanism, which leads to transcriptional activation. The CREST-BRG1 complex also binds to the NR2B promoter, and activity-dependent induction of NR2B expression involves a release of HDAC1 and recruitment of CREBBP (By similarity). {ECO:0000250}.

check buttonRetention analysis result of each fusion partner protein across 39 protein features of UniProt such as six molecule processing features, 13 region features, four site features, six amino acid modification features, two natural variation features, five experimental info features, and 3 secondary structure features. Here, because of limited space for viewing, we only show the protein feature retention information belong to the 13 regional features. All retention annotation result can be downloaded at

download page


* Minus value of BPloci means that the break pointn is located before the CDS.
- In-frame and retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
TgenePRKG1chr9:100745891chr10:53814244ENST00000373980418360_619254687.0DomainProtein kinase
TgenePRKG1chr9:100745891chr10:53814244ENST00000373980418620_671254687.0DomainAGC-kinase C-terminal
TgenePRKG1chr9:100745891chr10:53814244ENST00000401604418360_619239672.0DomainProtein kinase
TgenePRKG1chr9:100745891chr10:53814244ENST00000401604418620_671239672.0DomainAGC-kinase C-terminal
TgenePRKG1chr9:100745891chr10:53814244ENST00000373980418291_294254687.0Nucleotide binding3'%2C5'-cGMP 2
TgenePRKG1chr9:100745891chr10:53814244ENST00000373980418301_302254687.0Nucleotide binding3'%2C5'-cGMP 2
TgenePRKG1chr9:100745891chr10:53814244ENST00000373980418366_374254687.0Nucleotide bindingATP
TgenePRKG1chr9:100745891chr10:53814244ENST00000401604418291_294239672.0Nucleotide binding3'%2C5'-cGMP 2
TgenePRKG1chr9:100745891chr10:53814244ENST00000401604418301_302239672.0Nucleotide binding3'%2C5'-cGMP 2
TgenePRKG1chr9:100745891chr10:53814244ENST00000401604418366_374239672.0Nucleotide bindingATP

- In-frame and not-retained protein feature among the 13 regional features.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenProtein featureProtein feature note
HgeneANP32Bchr9:100745891chr10:53814244ENST00000339399+17146_25118252.0Compositional biasNote=Asp/Glu-rich (highly acidic)
HgeneANP32Bchr9:100745891chr10:53814244ENST00000339399+17123_16118252.0DomainNote=LRRCT
HgeneANP32Bchr9:100745891chr10:53814244ENST00000339399+17239_24218252.0MotifNuclear localization signal
HgeneANP32Bchr9:100745891chr10:53814244ENST00000339399+1716_4018252.0RepeatLRR 1
HgeneANP32Bchr9:100745891chr10:53814244ENST00000339399+1743_6418252.0RepeatLRR 2
HgeneANP32Bchr9:100745891chr10:53814244ENST00000339399+1765_8418252.0RepeatLRR 3
HgeneANP32Bchr9:100745891chr10:53814244ENST00000339399+1789_11018252.0RepeatLRR 4
TgenePRKG1chr9:100745891chr10:53814244ENST000003739804182_59254687.0Coiled coilOntology_term=ECO:0000269
TgenePRKG1chr9:100745891chr10:53814244ENST000004016044182_59239672.0Coiled coilOntology_term=ECO:0000269
TgenePRKG1chr9:100745891chr10:53814244ENST00000373980418167_170254687.0Nucleotide binding3'%2C5'-cGMP 1
TgenePRKG1chr9:100745891chr10:53814244ENST00000373980418177_178254687.0Nucleotide binding3'%2C5'-cGMP 1
TgenePRKG1chr9:100745891chr10:53814244ENST00000401604418167_170239672.0Nucleotide binding3'%2C5'-cGMP 1
TgenePRKG1chr9:100745891chr10:53814244ENST00000401604418177_178239672.0Nucleotide binding3'%2C5'-cGMP 1
TgenePRKG1chr9:100745891chr10:53814244ENST00000373980418103_220254687.0RegionNote=cGMP-binding%2C high affinity
TgenePRKG1chr9:100745891chr10:53814244ENST00000373980418221_341254687.0RegionNote=cGMP-binding%2C low affinity
TgenePRKG1chr9:100745891chr10:53814244ENST000003739804182_102254687.0RegionNote=Required for dimerization
TgenePRKG1chr9:100745891chr10:53814244ENST0000037398041850_75254687.0RegionAutoinhibitory domain
TgenePRKG1chr9:100745891chr10:53814244ENST000003739804189_44254687.0RegionNote=Leucine-zipper
TgenePRKG1chr9:100745891chr10:53814244ENST00000401604418103_220239672.0RegionNote=cGMP-binding%2C high affinity
TgenePRKG1chr9:100745891chr10:53814244ENST00000401604418221_341239672.0RegionNote=cGMP-binding%2C low affinity
TgenePRKG1chr9:100745891chr10:53814244ENST000004016044182_102239672.0RegionNote=Required for dimerization
TgenePRKG1chr9:100745891chr10:53814244ENST0000040160441850_75239672.0RegionAutoinhibitory domain
TgenePRKG1chr9:100745891chr10:53814244ENST000004016044189_44239672.0RegionNote=Leucine-zipper


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Fusion Gene Sequence for ANP32B-PRKG1


check button For in-frame fusion transcripts, we provide the fusion transcript sequences and fusion amino acid sequences. To have fusion amino acid sequence, we ran ORFfinder and chose the longest ORF among the all predicted ones.
>4972_4972_1_ANP32B-PRKG1_ANP32B_chr9_100745891_ENST00000339399_PRKG1_chr10_53814244_ENST00000373980_length(transcript)=5998nt_BP=249nt
CTCCGCTCCCGTGAGTAACTTGGCTCCGGGGGCTCCGCTCGCCTGCCCGCACGCCGCCCGCCACCCAGGACCGCGCCGCCGGCCTCCGCC
GCTAGCAAACCCTTCCGACGGCCCTCGCTGCGCAAGCCGGGACGCCTCTCCCCCCTCCGCCCCCGCCGCGGAAAGTTAAGTTTGAAGAGG
GGGGAAGAGGGGAACATGGACATGAAGAGGAGGATCCACCTGGAGCTGAGGAACCGGACCCCGGCAGCTACCCACTATGAAAATGGAGAA
TATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCTTTATCATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAA
GACCCAGTCTTTCTTAGAACTTTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTGAGAACAGCAAACGTAATT
GCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAGACTCTTTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATAT
GAAGATGCAGAAGCTAAAGCAAAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTCAACATCATTGATACCCTT
GGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGTTGAAAAGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCAC
ATTGTGGACACAAGACAGCAGGAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTTCATAGTGAGACTGTACAGA
ACATTTAAGGACAGCAAATATTTGTATATGTTGATGGAAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTT
GAAGATTCTACAACCAGATTTTACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATCATTTACAGGGACCTCAAG
CCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCAAACTGGTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGG
ACTTTTTGTGGGACTCCAGAGTATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGACTACTGGTCACTGGGAATC
CTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCTCAGGCCCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATG
ATAGAATTTCCAAAGAAGATTGCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATCAGAAAGATTAGGGAATTTG
AAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGTTTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATA
ATACCAAGTGTTGCATCACCCACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACCACCTGATGACAACTCAGGA
TGGGATATAGACTTCTAATGTATTTCTCTTACCTGCTTCTGCCTTGCTGAAGACAGCTTTTTCTGAGACACAGCTGCCAGCAAACCTGAG
GGAAAGAGAGAAGATTAGTGCTCGGGGTCACCATGATGCCTTTGATCGATGCTGCTCCAGTAACTACAGTGGCATTAGGACTTACCGCTT
AGATGACAATAGTGCTCTTTACATGTTTTCTGTTTGAACCTAAAATAGCAGTTGACATGGTGGTCCTGAAGCAAAGCCTTTCACCAGTAA
AAGATGTTTTCTATTGTTGCAATGACCTTGCTTTGCTCTGATTATAATTTGAAAGACTGTAGGAAACACTTCAATGTAGTATAAGAGTCT
GTACCTTGCTGGAATATTCAAGAAGATGAAAGAATAATATATTGGGTACAATAGATTACTATGGTACAGAAACTGGGCTATTCCCTTTCT
TCAAGTGAAGGCTGTGGGATCTATTACTGCAGGCCGGTGTATATACCATACAAAAGAGGACCACACATCTGTTGGTCACAGAGTTCATGT
CACACCAGTGCTAGAAGTTTCATGATTTTATTTCCCAGCAGTGCTGATGACAAGACTGAATGTTACCTTTTCTTTCTGACAGATTTTAAA
AATTGATATGATAAAAGCACAACTGCTATAGATTCTGCTGAGACCTCTCATAGTAGGTATATATGAGTTTTCACAGAAGACTGAAAAATA
ATGCATGATATTTGTTTGTTTTTTTTGATAAATTGGCATGACAGAGTGGGGAAAAAAAGCAATTCACAAAACCATTTCATATTTTTTAAA
ATATTGTGCTTAAAGATGGTCCTGGAAGTAAATGACTAGCAGCCAATTGGTTTTACTTAACATACCCTCAAACTGAGGCTTAAAGTATTC
CCTTTTATAAAAATAAATGCTTGGGGTAGGGTGGAGTGGGGAGGGATTAAAACCCATCCAAAAAATAAATAAAAACTATATAGGTGCTAT
GTATATCTTTCATCTGTAAATGTCAGTGTCTGAACAGACAACACAAATTCAAATCATTATACGTGTAGCCAGAAACTCAAGCATTTTCAC
TAAAGTTATTAAACCAAACTCCTGTCCAATTTCACTTATACAACATAGTCAGTCTAGAGTTGAGAGACAAAGGTAATTATAAACCTATTT
GAACTAGCTTCTTGTCTTAGGCCTGAACCAAAAAACAACAAACAAACAAAAAACAAGAATGAAAAACAGAAATAAAAGAAGTAGAAAAGA
CAAAGAAAGAAAGCCCAAAGTCAAAGTTGTTAATATTTACAGGTTTACCAGATCTGGAACATTACTTATTTGAGGTCAGAGAACAAAACA
AGAACCTGGCCAGGTGTTGATTACCTTTTAGTGAATAAGCTGAGTCCATATACTTGTCTAACTAAGAAAGCAGTACAGAGGAAAACAGGA
ACCTGATTTTTTTAAAATAAATTTTAAATAAAATAGAATTACTACAATTCTGCAATTTCATACTACCTAAAAAAGACTAGATTTGAAAAT
GTCAAGCTGATTTACTTTATTCACATGGAGAAAAGAATCCACAAATTAAACTGAGTCCTTCACTGGCATGCCAGTTGACTATTATTAGCT
GTCATAAGTAACTCAGCCATTTGGAAGCATTTCCTGGACAAAATTACATTATACCTGTGAAGAAAAATATAGAAGCTTTCAAGCTGTCAT
TCTGTTTTGGCCCTGTGTGAATTTGGTATATTAAATTGACGCTTGCTTTTTTTTTCAGTAGAGTTTTCTTTTTAATCAATCAAACGCCTA
CATTTCTGGAAGAAAAAGTCCAATTAGATCATTACACCTTAACTAAGAAGGCAAATCTTATAAATTTTGCTTGAATTGTTCTTACTCAAA
ACTACCTTAGAATATGGTATCTTATGAAAATATAATATTCTTAAAATTTTGGAGGATAAAATGAAAAGGGTATAAACTTCAATTAGAACT
TTAATCCTAAAATATTGTTATTCTTGTATTTTTGGAGTTTTCCGTCCCTTACAATTTCTCCAAATTGGTCTATTCCCCAAGATATCCACT
GTTTTCTACAGATTTTAGAATATAAAATTAAACATATCAACCTAAAATCTAGCTATGAATGTTATTTCAAGAGTTTTATATTTTTAATTG
GCTTTTTAAAAATATGTAATTCCAATATTATAGTGAATGTTCAGTAACTTTTGTTGAAAGATAATGTGGTTTAGGCTTGCTAAAGAAAGG
CTTGCTAGAATACTAAATTTACCTTGTTATTTGGAAAGAGAATCTGCTCCTATAACGTTTTAAAAATCCCCAAAGTCCCAGAGATTAGCA
CTTGCTATGGATTTTGGAACTATGGTTCAAGTCTAAGACAACCAATATGAATAAGTTCAATGGAGAAGGAAGAAGTAGCATTCAGCACAA
GAAACTGTAGATTGTTTCTCCCACTTGTTACTGCATCTTTGTTCATTTCACCCATAGCATTGCATTTGATGTCTGAAGTAATTACCACAA
AATAAAGGTAAACTACATCTTCCAAGATGTACCAACAGAAAACATTCGTCTAATTTTGTCAACATTGAATTTTTAGGATTTAAATCTTGT
CTTAATGAAGACTCTAGGGCTAAAATTCATGGTCAGTTCCATAAAATGCATCTCACTTTATTTCTGAATTTTTCACAACCCCTCTATTTT
CTTACATTAAAGAACATCTGGATAAGTTAGAATAGTGCCAACTTGTTTGATTTGTTATATGATTTTCTTGTTAATGTGTTGAGTATGGGA
AATAAGGGCTTTCTGTGTGTCTTGACTCACAGGAAAACTGAAACTGCCAAGGGAAGCAACATTAAAACAACTGGGATAGATTGAATACAT
TTGAAAAAATAATTTCTGGAAAAACGCTATACATGCTTTTTATGTTTATATCTTCTTTCTTATTAAGACATGAATCAGATCCATGTGGCA
TTCAAAACAAATTTATTTTGGTTATATTCTTTACAAGTCATAATTTTTACCTAAAATTGTGGAATATGCATGTGAATTACACATGTGTAG
TAATAAACTCAACTATTGAATTTTTCCTGTTTCATTTCTAAATGACTGAACTGATGGTAAACAAATTTAATGAAGTCAGCTACCATGTTG
AAAATAAGGATATTAGAACTGATTTCATACAATAGAGGTGATCTGTGCATTATCCATAACAACGTTTTCTTTCACTATAGGACCACAGAC
AAATATTTATGTAAATAGGTATTTTTGTGTGATATTTTGTGGTACATATAACTTTTTTTAGTGTTTCACAGCATTATTATTTCATTTTAT
TTGTATTGAATAATGTTTTTAGGTCCAAGTAGACTTGAATTAATGTCATAATTGTCAGTATTATTGAAAATTATGTCAACTGTACTGTTA
TTCATCTGTCCCATAGTTTAGAACATGACCTGGCTATCTGGCATTGTTGCAAGTGCCTTAAATTCATGGCATCCTATTAAAAAAACAAAT
TTGGTGTTATGCTGCATGACAAAGACAAACACACCTCAAAATGTTGTCCTTTCTTAGCTTGCTGCGTTTTACAGTTCTTTCTGCTAACAA
TTTATAAGCCTTTATTATATAATATTGATGAATTACAGAAATGATGAAGTTGTTCTCTTATTTCTGTTAAATGTACCAGAGCTGTGTATC
TGTTAATGAGATACAGCGTCATTTCTGTGAAATGTATAAATGTATGTGCAGGTCAAATTAATATATGACATTCTATCAGTCTGTATACAG
GTATTCCTGTTTTGCTAAGCTGTGCAGATTCTGTAAAAATAAATTAGTGCAGTCAAGTTCTAACATATCTCATTTTATAGACTCCATTGA
CAATGGTCCAACCGAAAAGAAAAATTGGAAATGACTGCTAACCAGACCTCGTTATGAAACCAATGATGAAAAAGTCACTTGGTGCACCTC
TCAACAAAACAGGATGCTTTTTCCGAGTTCTTGTATATGCAAATCATTTACGAGGCAAGTTTTCAACAGACCTAGAAAGCAAAACATTGA
AAGTGTGTTGTTAGCCCTCCTCTCTGCCCCTGAATCAACAGACAGAGCTCTGGGACCTTGGCAATGACTCAGAGGTTGGGGCTTTCTGAG
TAAAGGGACATTTCTTTAAGCATCATCTATCAAATTTATTTCAATGTATGATGTTTTTACAACTGGTCAGTTCTTTTGTATTCTTACAGC
TATGGTTATTTGATTGTCCTCTTACAATTTGTTCTACATGAAAGAGTTCTTTGTTAGTCAGAATGCAACAAACTGTCATCAAATGGTCAT
TGACCACTTGCACTCTTTTGATGTAGATTAAAAACTTTTTCATAAATTTACCTGCTTTGATTTGCTCTGTATTTTTCCTGCAGCTGTAAT

>4972_4972_1_ANP32B-PRKG1_ANP32B_chr9_100745891_ENST00000339399_PRKG1_chr10_53814244_ENST00000373980_length(amino acids)=501AA_BP=69
MPARRPPPRTAPPASAASKPFRRPSLRKPGRLSPLRPRRGKLSLKRGEEGNMDMKRRIHLELRNRTPAATHYENGEYIIRQGARGDTFFI
ISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAA
FFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEA
CLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEII
LNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFE

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>4972_4972_2_ANP32B-PRKG1_ANP32B_chr9_100745891_ENST00000339399_PRKG1_chr10_53814244_ENST00000373985_length(transcript)=5998nt_BP=249nt
CTCCGCTCCCGTGAGTAACTTGGCTCCGGGGGCTCCGCTCGCCTGCCCGCACGCCGCCCGCCACCCAGGACCGCGCCGCCGGCCTCCGCC
GCTAGCAAACCCTTCCGACGGCCCTCGCTGCGCAAGCCGGGACGCCTCTCCCCCCTCCGCCCCCGCCGCGGAAAGTTAAGTTTGAAGAGG
GGGGAAGAGGGGAACATGGACATGAAGAGGAGGATCCACCTGGAGCTGAGGAACCGGACCCCGGCAGCTACCCACTATGAAAATGGAGAA
TATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCTTTATCATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAA
GACCCAGTCTTTCTTAGAACTTTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTGAGAACAGCAAACGTAATT
GCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAGACTCTTTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATAT
GAAGATGCAGAAGCTAAAGCAAAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTCAACATCATTGATACCCTT
GGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGTTGAAAAGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCAC
ATTGTGGACACAAGACAGCAGGAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTTCATAGTGAGACTGTACAGA
ACATTTAAGGACAGCAAATATTTGTATATGTTGATGGAAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTT
GAAGATTCTACAACCAGATTTTACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATCATTTACAGGGACCTCAAG
CCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCAAACTGGTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGG
ACTTTTTGTGGGACTCCAGAGTATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGACTACTGGTCACTGGGAATC
CTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCTCAGGCCCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATG
ATAGAATTTCCAAAGAAGATTGCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATCAGAAAGATTAGGGAATTTG
AAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGTTTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATA
ATACCAAGTGTTGCATCACCCACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACCACCTGATGACAACTCAGGA
TGGGATATAGACTTCTAATGTATTTCTCTTACCTGCTTCTGCCTTGCTGAAGACAGCTTTTTCTGAGACACAGCTGCCAGCAAACCTGAG
GGAAAGAGAGAAGATTAGTGCTCGGGGTCACCATGATGCCTTTGATCGATGCTGCTCCAGTAACTACAGTGGCATTAGGACTTACCGCTT
AGATGACAATAGTGCTCTTTACATGTTTTCTGTTTGAACCTAAAATAGCAGTTGACATGGTGGTCCTGAAGCAAAGCCTTTCACCAGTAA
AAGATGTTTTCTATTGTTGCAATGACCTTGCTTTGCTCTGATTATAATTTGAAAGACTGTAGGAAACACTTCAATGTAGTATAAGAGTCT
GTACCTTGCTGGAATATTCAAGAAGATGAAAGAATAATATATTGGGTACAATAGATTACTATGGTACAGAAACTGGGCTATTCCCTTTCT
TCAAGTGAAGGCTGTGGGATCTATTACTGCAGGCCGGTGTATATACCATACAAAAGAGGACCACACATCTGTTGGTCACAGAGTTCATGT
CACACCAGTGCTAGAAGTTTCATGATTTTATTTCCCAGCAGTGCTGATGACAAGACTGAATGTTACCTTTTCTTTCTGACAGATTTTAAA
AATTGATATGATAAAAGCACAACTGCTATAGATTCTGCTGAGACCTCTCATAGTAGGTATATATGAGTTTTCACAGAAGACTGAAAAATA
ATGCATGATATTTGTTTGTTTTTTTTGATAAATTGGCATGACAGAGTGGGGAAAAAAAGCAATTCACAAAACCATTTCATATTTTTTAAA
ATATTGTGCTTAAAGATGGTCCTGGAAGTAAATGACTAGCAGCCAATTGGTTTTACTTAACATACCCTCAAACTGAGGCTTAAAGTATTC
CCTTTTATAAAAATAAATGCTTGGGGTAGGGTGGAGTGGGGAGGGATTAAAACCCATCCAAAAAATAAATAAAAACTATATAGGTGCTAT
GTATATCTTTCATCTGTAAATGTCAGTGTCTGAACAGACAACACAAATTCAAATCATTATACGTGTAGCCAGAAACTCAAGCATTTTCAC
TAAAGTTATTAAACCAAACTCCTGTCCAATTTCACTTATACAACATAGTCAGTCTAGAGTTGAGAGACAAAGGTAATTATAAACCTATTT
GAACTAGCTTCTTGTCTTAGGCCTGAACCAAAAAACAACAAACAAACAAAAAACAAGAATGAAAAACAGAAATAAAAGAAGTAGAAAAGA
CAAAGAAAGAAAGCCCAAAGTCAAAGTTGTTAATATTTACAGGTTTACCAGATCTGGAACATTACTTATTTGAGGTCAGAGAACAAAACA
AGAACCTGGCCAGGTGTTGATTACCTTTTAGTGAATAAGCTGAGTCCATATACTTGTCTAACTAAGAAAGCAGTACAGAGGAAAACAGGA
ACCTGATTTTTTTAAAATAAATTTTAAATAAAATAGAATTACTACAATTCTGCAATTTCATACTACCTAAAAAAGACTAGATTTGAAAAT
GTCAAGCTGATTTACTTTATTCACATGGAGAAAAGAATCCACAAATTAAACTGAGTCCTTCACTGGCATGCCAGTTGACTATTATTAGCT
GTCATAAGTAACTCAGCCATTTGGAAGCATTTCCTGGACAAAATTACATTATACCTGTGAAGAAAAATATAGAAGCTTTCAAGCTGTCAT
TCTGTTTTGGCCCTGTGTGAATTTGGTATATTAAATTGACGCTTGCTTTTTTTTTCAGTAGAGTTTTCTTTTTAATCAATCAAACGCCTA
CATTTCTGGAAGAAAAAGTCCAATTAGATCATTACACCTTAACTAAGAAGGCAAATCTTATAAATTTTGCTTGAATTGTTCTTACTCAAA
ACTACCTTAGAATATGGTATCTTATGAAAATATAATATTCTTAAAATTTTGGAGGATAAAATGAAAAGGGTATAAACTTCAATTAGAACT
TTAATCCTAAAATATTGTTATTCTTGTATTTTTGGAGTTTTCCGTCCCTTACAATTTCTCCAAATTGGTCTATTCCCCAAGATATCCACT
GTTTTCTACAGATTTTAGAATATAAAATTAAACATATCAACCTAAAATCTAGCTATGAATGTTATTTCAAGAGTTTTATATTTTTAATTG
GCTTTTTAAAAATATGTAATTCCAATATTATAGTGAATGTTCAGTAACTTTTGTTGAAAGATAATGTGGTTTAGGCTTGCTAAAGAAAGG
CTTGCTAGAATACTAAATTTACCTTGTTATTTGGAAAGAGAATCTGCTCCTATAACGTTTTAAAAATCCCCAAAGTCCCAGAGATTAGCA
CTTGCTATGGATTTTGGAACTATGGTTCAAGTCTAAGACAACCAATATGAATAAGTTCAATGGAGAAGGAAGAAGTAGCATTCAGCACAA
GAAACTGTAGATTGTTTCTCCCACTTGTTACTGCATCTTTGTTCATTTCACCCATAGCATTGCATTTGATGTCTGAAGTAATTACCACAA
AATAAAGGTAAACTACATCTTCCAAGATGTACCAACAGAAAACATTCGTCTAATTTTGTCAACATTGAATTTTTAGGATTTAAATCTTGT
CTTAATGAAGACTCTAGGGCTAAAATTCATGGTCAGTTCCATAAAATGCATCTCACTTTATTTCTGAATTTTTCACAACCCCTCTATTTT
CTTACATTAAAGAACATCTGGATAAGTTAGAATAGTGCCAACTTGTTTGATTTGTTATATGATTTTCTTGTTAATGTGTTGAGTATGGGA
AATAAGGGCTTTCTGTGTGTCTTGACTCACAGGAAAACTGAAACTGCCAAGGGAAGCAACATTAAAACAACTGGGATAGATTGAATACAT
TTGAAAAAATAATTTCTGGAAAAACGCTATACATGCTTTTTATGTTTATATCTTCTTTCTTATTAAGACATGAATCAGATCCATGTGGCA
TTCAAAACAAATTTATTTTGGTTATATTCTTTACAAGTCATAATTTTTACCTAAAATTGTGGAATATGCATGTGAATTACACATGTGTAG
TAATAAACTCAACTATTGAATTTTTCCTGTTTCATTTCTAAATGACTGAACTGATGGTAAACAAATTTAATGAAGTCAGCTACCATGTTG
AAAATAAGGATATTAGAACTGATTTCATACAATAGAGGTGATCTGTGCATTATCCATAACAACGTTTTCTTTCACTATAGGACCACAGAC
AAATATTTATGTAAATAGGTATTTTTGTGTGATATTTTGTGGTACATATAACTTTTTTTAGTGTTTCACAGCATTATTATTTCATTTTAT
TTGTATTGAATAATGTTTTTAGGTCCAAGTAGACTTGAATTAATGTCATAATTGTCAGTATTATTGAAAATTATGTCAACTGTACTGTTA
TTCATCTGTCCCATAGTTTAGAACATGACCTGGCTATCTGGCATTGTTGCAAGTGCCTTAAATTCATGGCATCCTATTAAAAAAACAAAT
TTGGTGTTATGCTGCATGACAAAGACAAACACACCTCAAAATGTTGTCCTTTCTTAGCTTGCTGCGTTTTACAGTTCTTTCTGCTAACAA
TTTATAAGCCTTTATTATATAATATTGATGAATTACAGAAATGATGAAGTTGTTCTCTTATTTCTGTTAAATGTACCAGAGCTGTGTATC
TGTTAATGAGATACAGCGTCATTTCTGTGAAATGTATAAATGTATGTGCAGGTCAAATTAATATATGACATTCTATCAGTCTGTATACAG
GTATTCCTGTTTTGCTAAGCTGTGCAGATTCTGTAAAAATAAATTAGTGCAGTCAAGTTCTAACATATCTCATTTTATAGACTCCATTGA
CAATGGTCCAACCGAAAAGAAAAATTGGAAATGACTGCTAACCAGACCTCGTTATGAAACCAATGATGAAAAAGTCACTTGGTGCACCTC
TCAACAAAACAGGATGCTTTTTCCGAGTTCTTGTATATGCAAATCATTTACGAGGCAAGTTTTCAACAGACCTAGAAAGCAAAACATTGA
AAGTGTGTTGTTAGCCCTCCTCTCTGCCCCTGAATCAACAGACAGAGCTCTGGGACCTTGGCAATGACTCAGAGGTTGGGGCTTTCTGAG
TAAAGGGACATTTCTTTAAGCATCATCTATCAAATTTATTTCAATGTATGATGTTTTTACAACTGGTCAGTTCTTTTGTATTCTTACAGC
TATGGTTATTTGATTGTCCTCTTACAATTTGTTCTACATGAAAGAGTTCTTTGTTAGTCAGAATGCAACAAACTGTCATCAAATGGTCAT
TGACCACTTGCACTCTTTTGATGTAGATTAAAAACTTTTTCATAAATTTACCTGCTTTGATTTGCTCTGTATTTTTCCTGCAGCTGTAAT

>4972_4972_2_ANP32B-PRKG1_ANP32B_chr9_100745891_ENST00000339399_PRKG1_chr10_53814244_ENST00000373985_length(amino acids)=501AA_BP=69
MPARRPPPRTAPPASAASKPFRRPSLRKPGRLSPLRPRRGKLSLKRGEEGNMDMKRRIHLELRNRTPAATHYENGEYIIRQGARGDTFFI
ISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAA
FFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEA
CLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEII
LNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFE

--------------------------------------------------------------
>4972_4972_3_ANP32B-PRKG1_ANP32B_chr9_100745891_ENST00000339399_PRKG1_chr10_53814244_ENST00000401604_length(transcript)=3162nt_BP=249nt
CTCCGCTCCCGTGAGTAACTTGGCTCCGGGGGCTCCGCTCGCCTGCCCGCACGCCGCCCGCCACCCAGGACCGCGCCGCCGGCCTCCGCC
GCTAGCAAACCCTTCCGACGGCCCTCGCTGCGCAAGCCGGGACGCCTCTCCCCCCTCCGCCCCCGCCGCGGAAAGTTAAGTTTGAAGAGG
GGGGAAGAGGGGAACATGGACATGAAGAGGAGGATCCACCTGGAGCTGAGGAACCGGACCCCGGCAGCTACCCACTATGAAAATGGAGAA
TATATTATCAGGCAAGGTGCAAGAGGGGACACCTTCTTTATCATCAGCAAAGGAACGGTAAATGTCACTCGTGAAGACTCACCGAGTGAA
GACCCAGTCTTTCTTAGAACTTTAGGAAAAGGAGACTGGTTTGGAGAGAAAGCCTTGCAGGGGGAAGATGTGAGAACAGCAAACGTAATT
GCTGCAGAAGCTGTAACCTGCCTTGTGATTGACAGAGACTCTTTTAAACATTTGATTGGAGGGCTGGATGATGTTTCTAATAAAGCATAT
GAAGATGCAGAAGCTAAAGCAAAATATGAAGCTGAAGCGGCTTTCTTCGCCAACCTGAAGCTGTCTGATTTCAACATCATTGATACCCTT
GGAGTTGGAGGTTTCGGACGAGTAGAACTGGTCCAGTTGAAAAGTGAAGAATCCAAAACGTTTGCAATGAAGATTCTCAAGAAACGTCAC
ATTGTGGACACAAGACAGCAGGAGCACATCCGCTCAGAGAAGCAGATCATGCAGGGGGCTCATTCCGATTTCATAGTGAGACTGTACAGA
ACATTTAAGGACAGCAAATATTTGTATATGTTGATGGAAGCTTGTCTAGGTGGAGAGCTCTGGACCATTCTCAGGGATAGAGGTTCGTTT
GAAGATTCTACAACCAGATTTTACACAGCATGTGTGGTAGAAGCTTTTGCCTATCTGCATTCCAAAGGAATCATTTACAGGGACCTCAAG
CCAGAAAATCTCATCCTAGATCACCGAGGTTATGCCAAACTGGTTGATTTTGGCTTTGCAAAGAAAATAGGATTTGGAAAGAAAACATGG
ACTTTTTGTGGGACTCCAGAGTATGTAGCCCCAGAGATCATCCTGAACAAAGGCCATGACATTTCAGCCGACTACTGGTCACTGGGAATC
CTAATGTATGAACTCCTGACTGGCAGCCCACCTTTCTCAGGCCCAGATCCTATGAAAACCTATAACATCATATTGAGGGGGATTGACATG
ATAGAATTTCCAAAGAAGATTGCCAAAAATGCTGCTAATTTAATTAAAAAACTATGCAGGGACAATCCATCAGAAAGATTAGGGAATTTG
AAAAATGGAGTAAAAGACATTCAAAAGCACAAATGGTTTGAGGGCTTTAACTGGGAAGGCTTAAGAAAAGGTACCTTGACACCTCCTATA
ATACCAAGTGTTGCATCACCCACAGACACAAGTAATTTTGACAGTTTCCCTGAGGACAACGATGAACCACCACCTGATGACAACTCAGGA
TGGGATATAGACTTCTAATGTATTTCTCTTACCTGCTTCTGCCTTGCTGAAGACAGCTTTTTCTGAGACACAGCTGCCAGCAAACCTGAG
GGAAAGAGAGAAGATTAGTGCTCGGGGTCACCATGATGCCTTTGATCGATGCTGCTCCAGTAACTACAGTGGCATTAGGACTTACCGCTT
AGATGACAATAGTGCTCTTTACATGTTTTCTGTTTGAACCTAAAATAGCAGTTGACATGGTGGTCCTGAAGCAAAGCCTTTCACCAGTAA
AAGATGTTTTCTATTGTTGCAATGACCTTGCTTTGCTCTGATTATAATTTGAAAGACTGTAGGAAACACTTCAATGTAGTATAAGAGTCT
GTACCTTGCTGGAATATTCAAGAAGATGAAAGAATAATATATTGGGTACAATAGATTACTATGGTACAGAAACTGGGCTATTCCCTTTCT
TCAAGTGAAGGCTGTGGGATCTATTACTGCAGGCCGGTGTATATACCATACAAAAGAGGACCACACATCTGTTGGTCACAGAGTTCATGT
CACACCAGTGCTAGAAGTTTCATGATTTTATTTCCCAGCAGTGCTGATGACAAGACTGAATGTTACCTTTTCTTTCTGACAGATTTTAAA
AATTGATATGATAAAAGCACAACTGCTATAGATTCTGCTGAGACCTCTCATAGTAGGTATATATGAGTTTTCACAGAAGACTGAAAAATA
ATGCATGATATTTGTTTGTTTTTTTTGATAAATTGGCATGACAGAGTGGGGAAAAAAAGCAATTCACAAAACCATTTCATATTTTTTAAA
ATATTGTGCTTAAAGATGGTCCTGGAAGTAAATGACTAGCAGCCAATTGGTTTTACTTAACATACCCTCAAACTGAGGCTTAAAGTATTC
CCTTTTATAAAAATAAATGCTTGGGGTAGGGTGGAGTGGGGAGGGATTAAAACCCATCCAAAAAATAAATAAAAACTATATAGGTGCTAT
GTATATCTTTCATCTGTAAATGTCAGTGTCTGAACAGACAACACAAATTCAAATCATTATACGTGTAGCCAGAAACTCAAGCATTTTCAC
TAAAGTTATTAAACCAAACTCCTGTCCAATTTCACTTATACAACATAGTCAGTCTAGAGTTGAGAGACAAAGGTAATTATAAACCTATTT
GAACTAGCTTCTTGTCTTAGGCCTGAACCAAAAAACAACAAACAAACAAAAAACAAGAATGAAAAACAGAAATAAAAGAAGTAGAAAAGA
CAAAGAAAGAAAGCCCAAAGTCAAAGTTGTTAATATTTACAGGTTTACCAGATCTGGAACATTACTTATTTGAGGTCAGAGAACAAAACA
AGAACCTGGCCAGGTGTTGATTACCTTTTAGTGAATAAGCTGAGTCCATATACTTGTCTAACTAAGAAAGCAGTACAGAGGAAAACAGGA
ACCTGATTTTTTTAAAATAAATTTTAAATAAAATAGAATTACTACAATTCTGCAATTTCATACTACCTAAAAAAGACTAGATTTGAAAAT
GTCAAGCTGATTTACTTTATTCACATGGAGAAAAGAATCCACAAATTAAACTGAGTCCTTCACTGGCATGCCAGTTGACTATTATTAGCT

>4972_4972_3_ANP32B-PRKG1_ANP32B_chr9_100745891_ENST00000339399_PRKG1_chr10_53814244_ENST00000401604_length(amino acids)=501AA_BP=69
MPARRPPPRTAPPASAASKPFRRPSLRKPGRLSPLRPRRGKLSLKRGEEGNMDMKRRIHLELRNRTPAATHYENGEYIIRQGARGDTFFI
ISKGTVNVTREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYEDAEAKAKYEAEAA
FFANLKLSDFNIIDTLGVGGFGRVELVQLKSEESKTFAMKILKKRHIVDTRQQEHIRSEKQIMQGAHSDFIVRLYRTFKDSKYLYMLMEA
CLGGELWTILRDRGSFEDSTTRFYTACVVEAFAYLHSKGIIYRDLKPENLILDHRGYAKLVDFGFAKKIGFGKKTWTFCGTPEYVAPEII
LNKGHDISADYWSLGILMYELLTGSPPFSGPDPMKTYNIILRGIDMIEFPKKIAKNAANLIKKLCRDNPSERLGNLKNGVKDIQKHKWFE

--------------------------------------------------------------

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Fusion Gene PPI Analysis for ANP32B-PRKG1


check button Go to ChiPPI (Chimeric Protein-Protein interactions) to see the chimeric PPI interaction in

ChiPPI page.


check button Protein-protein interactors with each fusion partner protein in wild-type (BIOGRID-3.4.160)
HgeneHgene's interactorsTgeneTgene's interactors


check button - Retained PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenStill interaction with


check button - Lost PPIs in in-frame fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


check button - Retained PPIs, but lost function due to frame-shift fusion.
PartnerGeneHbpTbpENSTStrandBPexonTotalExonProtein feature loci*BPlociTotalLenInteraction lost with


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Related Drugs for ANP32B-PRKG1


check button Drugs targeting genes involved in this fusion gene.
(DrugBank Version 5.1.8 2021-05-08)
PartnerGeneUniProtAccDrugBank IDDrug nameDrug activityDrug typeDrug status

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Related Diseases for ANP32B-PRKG1


check button Diseases associated with fusion partners.
(DisGeNet 4.0)
PartnerGeneDisease IDDisease name# pubmedsSource